* Black Bean, The Potent Legume Which Inhibits Early Onset and Progression of Chronic Diseases

By Kyle J. Norton


Compared to herbal medicine, food therapy even takes longer to ease symptoms, depending to stages of the treatment which directly address the cause of disease.

Intake black bean regularly may have a potential effect in attenuated risk and treatment of chronic diseases.

Chronic diseases are medical conditions that last at least 3 months. In all cases, according to conventional medicine, the diseases cannot heal themselves, be prevented by vaccines injection nor cured by medication.

Most common chronic diseases in the Western world include cancers, arthritis, heart attacks, and stroke. Ans most common types of cancer are breast and colon cancer, diabetes, epilepsy and seizures,..... and obesity.

According to statistic, almost one out of every two U.S. adults having at least one of six chronic illnesses. In other words, chronic conditions affect over 107 million people.

The Public Health and Chronic Disease wrote, " Seven out of 10 deaths among Americans each year are from chronic diseases. Heart disease, cancer, and stroke account for more than 50% of all yearly deaths" and "Diabetes is the leading cause of kidney failure, non-injury lower-limb amputations, and blindness among 20 to 74-year-olds".

In 2008, chronic diseases cost over  $147 billion annually in the US. and costs by $218 billion per year and reduce the economic impact of disease by $1.1 trillion annually.

As of today, health care coverage costs for people with a chronic condition average $6,032 annually, that is five times higher than for those without such a condition, the Partnership to Fight Chronic Diseases suggested.

The statistician of the World Health Organization (WHO) stated, chronic diseases
* are the leading cause of death worldwide.
* Ischemic heart disease alone was responsible for about 9.43 million deaths in 2016.
* However, all cardiovascular diseases together cause over 17.8 million deaths annually worldwide followed by cancers.

If you experience some chronic conditions that do not heal over 3 months, please check with your doctor to rule out the possibility.

The causes of chronic diseases are depended to a specific condition, however, some researchers suggested that a small set of common risk factors may be responsible for most of the main chronic diseases, including unhealthy diet and lifestyle, physical inactivity;.... and smoking

Others indicated that chronic diseases may also be initiated by some intermediate risk factors such as blood pressure, high blood cholesterol,.........., overweight and obesity.

Black bean is a small roughly ovoid legume with glossy black shells, genus Phaseolus, belongings to the family Fabaceae,  first cultivated in South America.

The beans can be bought in most grocery stores all around the year in dried and canned forms.

According to the University of Colorado Colorado Springs, the efficacy of legume in reduced chronic illness risk may be attributed to antioxidant phytochemical activities and other responses that influence the classification to types of diseases such as diabetes, CVD and cancer.

Dr. Hutchins AM, the lead scientist said, "Consumption of Phaseolus vulgaris bean species such as black beans,,,,,,,,,, may be beneficial in the prevention and treatment of chronic diseases. In particular, conditions that are promoted by increased glycaemic stress (hyperglycemia and hyperinsulinemia) including diabetes, CVD and cancer seem to be reduced in individuals who eat more of these beans"(1).

In protein and four synthesized pure peptides isolated Mexican black and Brazilian Carioca bean, researchers showed that application of purified peptides has a potential and therapeutic effect to serve as antidiabetic and antihypertensive agents in an animal model, regardless of their antioxidant capacity(2).

In details(2),
* Carioca Perola bean digested proteins processed the highest antioxidant capacity.

* Both beans and their peptides are potent against dipeptidyl peptidase-IV (DPP-IV) which is associated to the onset of diabetes and Angiotensin-converting enzyme (ACE) that is associated to cancer risk.
In fact, according to the Universidad Complutense de Madrid, types of carbohydrates found in black bean may be associated with a low glycemic response, low serum cholesterol levels, and a decrease of colon cancer risk factors as well as other forms of in chronic diseases such as diabetes type II and cardiovascular diseases.

Dr. Serrano J, the lead author, after taking into accounts of other co and confounder wrote, " These physiological effects in the treatment of chronic diseases may be related to colonic fermentation end products (propionic and butyric acids) (found in black beans)"(3).

Furthermore, black beans also contain several "antinutritional" compounds (enzymatic inhibitors, haemaglutenins, saponins and phytic acid(3), which may have potential effects by acting as an antioxidant against early onset and progression of chronic diseases.

Collectively, black bean reduced risk and treatment of chronic illness are the results of improved antioxidant status and other mechanisms, including reduction of glucose, triglycerides, total cholesterol, lower levels of LDL and Raised HDL as well as protecting pancreatic ß-cells, ...

Taking together, there is no doubt that black bean may be used as functional foods in attenuated risk and treatment of chronic disease, through antioxidant, anti-inflammatory, antiproliferative cardioprotective..... activities.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Phaseolus beans: impact on glycaemic response and chronic disease risk in human subjects by Hutchins AM1, Winham DM, Thompson SV.(PubMed)
(2) Characterization of peptides from common bean protein isolates and their potential to inhibit markers of type-2 diabetes, hypertension and oxidative stress by Mojica L1,2, Luna-Vital DA1,3, González de Mejía E1.(PubMed)
(3) [Role of black bean Phaseolus vulgaris on the nutritional status of Guatemalan population].
[Article in Spanish]by Serrano J1, Goñi I.(PubMed)

Green Tea, The Beverage That Suppresses Osteoarthritis

By Kyle J. Norton, Master of Nutrition


Regular drinking of green tea may have a positive effect in suppressed conditions that causes osteoarthritis, some study by respectable institute suggested.

Osteoarthritis (OA), is a form of arthritis characterized by aging progression of wear and tear on a joint, affecting over 25 million people in the United States alone.

Osteoarthritis is the single most common cause of disability in older adults. The disease even with today medical and  technological invention remains a serious health crisis in US and a global epidemic, too.

The 2010 Global Burden of Disease Study reports, according to the World health Organization (WHO), in assessments of world wide 6.8% musculoskeletal disorders population, 10% to 15% of all adults aged over 60 have some degrees of OA, with prevalence higher among women than men(4)..

Continuously, the WHO wrote, "The prevalence of OA is increasing due to population ageing and an increase in related factors such as obesity. According to the United Nations, by 2050 people aged over 60 will account for more than 20% of the world’s population" and  "by 2050, 130 million people will suffer from OA worldwide, of whom 40 million will be severely disabled by the disease.6 Costs associated with OA include costs for adaptive aids and devices, medicines, surgery, and time off at work"(4)

Some researchers suggested that the prevalence of OA will be increased substantially, if the organization is taking into account of increased obesity risk of Asian population, due to over 30 years of economic prosperity that influence many people who have made a lot of money to replace  traditional Asian diet with  American diet that is high on carbohydrate and saturated fat and trans fat.

Symptoms of osteoarthritis are associated to aching pain, stiffness, or difficulty moving the joint  that may develop in one or more joints. The pain usually gets worse in change of weather at night and in the advanced of the diseases, the pain can occur even at rest.

If you experience all of above symptoms, you may have osteoarthritis.

Gene inherited from parent, extreme over weight, previous joints injure, over use and patients with bone and joint disorders are most common causes and risk of factors of the disease.

Moreover, abnormal biomechanics, age-related sarcopenia and increased bone turnover may also contribute to the development of OA.

Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world.

In a randomized open-label active-controlled clinical trial of 50 adults with osteoarthritis of knee allocated to receive the green tea extract (in dosage form of tablet) plus diclofenac tablet as "intervention group"; or: diclofenac tablet alone as "control group" for a period of four weeks, researchers at the joint study lead by the Fasa University of Medical Sciences found that combination treated group exerted a significant improvement of physical function in compared to control(1).

Green tea extract and diclofenac tablet treatment group also expressed a progress in pain reduction during knee joint physical function in adults with osteoarthritis as in control group(1).

Dr. Hashempur MH, at the end of experiment period said, " ...green tea extract might well be considered as an adjunctive treatment both for control of pain and for the betterment of knee joint physical function in adults with osteoarthritis".

Additionally, in the compared the effect of curcuminoids extract, hydrolyzed collagen and green tea extract, in chondrocytes culture cells, researchers found that combination of all components score a enormous expression of reduced production of pro inflammatory cytokines through various mechanisms, including ameliorated free radical elucidation(2).

In human chondrocytes (cells that secreted the matrix of cartilage) and in the absence of interleukin 1β, combination with hydrolyzed collagen and green tea extract significantly inhibited matrix metalloproteinase-3 production which has a direct impact in denatured type I collagen(collagen fibers)(2).

Furthermore, in the presence of proinflammatory cytokine interleukin 1β, the combined application was significantly more efficient in inhibited interleukin-1β stimulated matrix metalloproteinase-3 expression than any individual extract.

Interleukin 1β, a protein is an important mediator of the immune systematic inflammatory response in acute phase of infection through its function as a proinflammatory cytokine to protect our body against foreign organism invasion(2).

Most importantly, all other factors that have contributed to the onset of osteoarthritis such as chondrocytes, nitric oxide, interleukin-6 were also inhibited by the combined injection, according to the record reported by Dr. Comblain F, the lead scientist(2).

In the support of the above differentiation, the study in the investigation of a posttraumatic osteoarthritis (OA) mouse model tested with EGCG against progression of OA and relieve OA-associated pain, researchers suggested that EGCG-treated mice promoted cartilage production against Safranin O, staining of the knee joint cartilage loss and cartilage erosion in compared to control group with no treatment(3).

Cartilage of treated mice also displayed a significant reduction of gene in regulated degeneration of connective tissue and pathways that involve promotional of tissues inflammation(3).

Additionally, pain score of treated mice also exhibited a significant enhancement in compared control group(3).

Taking together, there is no doubt that green tea process a therapeutic and integrated form of treatment by suppressing the conditions that cause symptoms of pain and physical disability and onset of  osteoarthritis.

However, further data collection on large example size and multi centers studies performed with human consumption of the whole food during the course of the disease will be necessary to complete the picture of green tea anti osteoarthritis possibilities.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1)Green tea (Camellia sinensis) for patients with knee osteoarthritis: A randomized open-label active-controlled clinical trial by Hashempur MH1, Sadrneshin S2, Mosavat SH3, Ashraf A4.(PubMed)
(2) Curcuminoids extract, hydrolyzed collagen and green tea extract synergically inhibit inflammatory and catabolic mediator's synthesis by normal bovine and osteoarthritic human chondrocytes in monolayer by Comblain F1, Sanchez C1, Lesponne I2, Balligand M3, Serisier S2, Henrotin Y4.(PubMed)
(3) Green tea polyphenol treatment is chondroprotective, anti-inflammatory and palliative in a mouse post-traumatic osteoarthritis model by Leong DJ, Choudhury M, Hanstein R, Hirsh DM, Kim SJ, Majeska RJ, Schaffler MB, Hardin JA, Spray DC, Goldring MB, Cobelli NJ, Sun HB.(PubMed)
(4) 6.12 Osteoarthritis By WHO

Butcher's Broom, the Functional Herb that May Cure Hemorrhoids

By Kyle J. Norton, Master of Nutrition


Herbal Butcher's broom may be used as a therapeutic treatment to cure hemorrhoids, some scientists suggested.

Hemorrhoids, also called piles are a common condition characterized by swollen veins in the anus and lower rectum.

The causes of hemorrhoids are unknown.

However, some researchers suggested that straining during bowel movements, a prolonged period of sitting due to the occupation that induces increased pressure on these veins are associated with the early onset of the condition.

In women, a pregnancy that causes pressure on the anus and swollen veins and lower rectum veins may also increase the risk of hemorrhoids.

According to statistic, a quarter of adults population in the US have hemorrhoids developed at some points in their lives.

Most patients with hemorrhoids do not experience any symptoms. But in some infectious cases, hemorrhoids may induce symptoms of itching, discomfort, and bleeding.

Please be aware that some internal hemorrhoids can grow so large that they stick out of the anus. Prolapsed hemorrhoids, most of the time may require surgery to heal.

If you experience some of the above symptoms, please see your doctor to rule out the possibility of digestive problems.

Hemorrhoids that burst may cause serve to bleed. The loss of a large amount of blood due to rupturing hemorrhoids can be life-threatening.

Some researchers suggested that stool softeners over-the-counter remedies and conventional anti-inflammatory ointments may be used to provide short-term local discomforts. and eating more fibers, drinking more water and preventing straining may also help to relieve hemorrhoids' symptoms.

Change of diet, lifestyle changes, and use of other transnational treatment such as hydrotherapy that require a high degree of patient compliance may also be helpful.

Conventional medical and surgical treatment may be needed, depending on the severity of the condition, please check with your doctors for more information.


Butcher's broom is a low evergreen shrub, a species of Ruscus aculeatus, belongings to the family Asparagaceae, native to Eurasia.

The herb has been used in herbal medicine to treat inflammation, peripheral vascular disease, hemorrhoids, bronchial asthma, varicose veins,.......and hypotension.


The Phyto ingredients
It contains rutin, sitosterol, sparteine, spirostanol saponins, steroidal sapogenins, sterols, stigmasterol, sulfated steroidal saponins, sweet broom, tetracosanoic acid, triterpenes, triterpines, tyramine, etc.

According to the Thorne Research, in compared to surgery that often is associated to certain risks, after non-surgical approach fails, that can lead a patient to postpone evaluation until aggressive intervention is necessary, oral dietary supplementation of butcher’s broom is an attractive and effective addition to the traditional treatment of hemorrhoids and varicose veins(1).

Dr. MacKay D, after taking to account co and confounders said, "Several botanical extracts(including those of butcher’s broom have been shown to improve microcirculation, capillary flow, and vascular tone, and to strengthen the connective tissue of the perivascular amorphous substrate"(1).

Etiologically, due to the relation of varicose and hemorrhoids, because both are manifestations of the study of a pelvic venous disease that has been treated effectively by application of Centella asiatica, researchers lead by Dr. Morgan suggested that Centella asiatica increases peripheral circulation, in hemorrhoids patients(2).


 Dr. Bharat Gami said, " Ruscus aculeatus is famous for the treatment in internal hemorrhoids and the pregnancy-related problem of CVI & hemorrhoids. Extract of these plants is effective in increasing venous tone because of its anti-inflammatory and astringent properties, which is attributed to saponin glycoside" and". At the beginning of hemorrhoids, it can be completely cured by botanicals. In addition to that changes in lifestyle, diet habit, and intake of an appropriate dose of proper botanicals gives intervene in the pathogenesis to decrease vascular integrity and help in hemorrhoids cure"(2).

Also, according to the research article in Page 608 Alternative Medicine Review ◆ Volume 6, Number 6, butcher’s broom was tested to have a significant effect on patients with hemorrhoids in an open trial, as 75 percent of participating physicians rated butcher’s broom’s efficacy as good or excellent(3).

Furthermore, application of the herbal medicine also is found to be effective in preventing time-consuming, painful, and expensive complications of hemorrhoids, such as anal discomfort, soiling and bleeding present in the acute phase(3).

The information finding indicated that herbal Butcher's broom may be as effective as conventional medicine and surgery in curing hemorrhoids with no or little side effects.

However, intake of herbal medicine and herbal extracts should only be prescribed by related field specialist in the prevention of acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Hemorrhoids and varicose veins: a review of treatment options by MacKay D.(PubMed)
(2) BOTANICALS AN ALTERNATIVE TREATMENT APPROACH FOR HEMORRHOIDS – A REVIEW by Dr. Bharat Gami
(3) Alternative Medicine Review Ruscus aculeatus (Butcher’s Broom)

* Herbal Emodin, The Bioactive Ingredient That Treats Herpes Simplex Virus Infection

By Kyle J. Norton

Herbal Cascara Sagrada containing major bioactive compound Emodin may be considered as a functional herb that inhibits diseases caused by infection of Herpes simplex virus, some scientists found.

Herpes simplex virus 1 and 2, the 2 members of the herpersvirus family, also are best known as human herpesvirus 1 and 2.

The classification of the virus are based on their likelihood to cause infection. According WHO(5), in expression of conventional medicine, there is no cure of the diseases and both HSV-1 and HSV-2 infections are lifelong.

* HSV-1 is mainly transmitted by oral-to-oral contact such as oral herpes.

* HSV-2 is a sexually transmitted infection.

However, both HSV-1 and HSV-2 can cause genital herpes.

According to statistic, approximately 3.7 billion people under age 50 (67%) are infected by HSV-1 and  417 million people aged 15-49 (11%) are infected by HSV-2 globally. 

Some patients infected by the virus do not experience any symptoms, however, some may affect by symptoms of painful blisters or ulcers at the site of infection.

The virus are very contagious in the presence of symptoms but they can also transmitt to other from virus carriers who experience no symptoms at all. 

Some researchers suggested that risk of HIV infection is strongly associated to patients who are infected by with HSV-2 with or without symptoms.

The study of risk factors of HSV-1 and 2  

* (HSV-1) By the University of Bielefeld includes coitus experience, oral lesion, seropositivity and a higher level of perceived stress. And according to the returned questionnaire from participants, most lifestyle, gender or age are not risk factors with drinking alcohol was found to be a protective factor(3). 

* (HSV-2) By the University of Washington, include, seropositivity (include female gender), race (black), history of sexually transmitted infections, increasing numbers of sexual partners, sexual contact with commercial sex workers and low socio-economic status or level of education. 

Particularly, age is considered as a related risk factors as it, likely reflects the cumulative number of sex partners, age of initiation of sexual activity, and duration of sexual activity as well as chronice nature of HSV-2 infection"(4). 

Conventional medicine used for treatment of herpes simplex virus may be effective but inducing serious side effects of nausea, diarrhea, vomiting, digestive discomforts, headache, dizziness. fatigue,....  joint and muscle aches. In serious case, the medicine may cause visual changes.

Cascara sagrada is a species of buckthorn, genus Rhamnus, belongings to the family Rhamnaceae, native to western North America.

The herbal medicine bark has been used in traditional medicine for gastrointestinal support, thought its laxative and natural cleansing,

The chemical ingredients
Beside the main compound of anthraquinones, otyher compounds include anthraquinone glycosides, (emodin, frangulin, iso-emodin, aloe-emodin, and chrysophanol), rhein, aloin, malic acid, tannic acid, cascarosides A, B, C, and D,...... and hydroxy anthracene derivatives (HAD).

Emodin, the major component found in many herbs including ascara Sagrada, in the study against HSV infection exerted a significant effect in inhibited the replication of HSV-1 and HSV-2 in cell culture at the concentration of 50 μg/ml with antiviral index of 2.07 and 3.53, respectively(1).
In animal model, treatment of emodin increased the survival rate of HSV-infected mice, prolonged survival time(1).

After additional analysis of the experiment Dr. Xiong HR, the lead author suggested, injection of emodin expressed a higher efficacy in eliminated the virus from brain, heart, liver and ganglion, in compared to the viral controls.

According to the differentiation of the China Medical University, application of emodin not only demonstrated a strong apoptotic activity in HSV cell cycle arrest, but also reduced the plaque formation with an EC(50) of 21.5+/-4.4 muM(2).

Virus plaque formation according to plaque reduction assay is a measurement of  plaque that the spread of progeny viruses released by individually infected cells is restricted to neighboring cells(7).

The Immunohistochemical staining using the anti-nucleocapsid protein antibody also demonstrated that emodin inhibited HSV infection through induced the accumulation of viral nucleocapsids (which refer to the protein coat (capsid) and the nucleic acid) in the nucleus in a dose-dependent manner(2).

More over, emodin also inhibited the yields of HSV-1 via the suppression of a novel target, UL12, a HSV-1 gene which plays an important role in processing viral DNA intermediates for survival by promoting production.

The findings suggested that herbal Cascara Sagrada process anti herpes simplex virus potential through cell cycle arrest and disrupted viral DNA which promotes reduplication.

However, further data collection on large example size and multi centers studies performed with human consumption of the whole food during the course of the disease will be necessary to complete the picture of Cascara Sagrada anti Herpes simplex virus possibilities.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
References
(1) The effect of emodin, an anthraquinone derivative extracted from the roots of Rheum tanguticum, against herpes simplex virus in vitro and in vivo by Xiong HR, Luo J, Hou W, Xiao H, Yang ZQ.(PubMed)
(2) Emodin is a novel alkaline nuclease inhibitor that suppresses herpes simplex virus type 1 yields in cell cultures by Hsiang CY, Ho TY.(PubMed)
(3) Herpes simplex virus type 2 transmission: risk factors and virus shedding by Wald A(PubMed)
(4) Risk factors of herpes simplex type 1 (HSV-1) infection and lifestyle factors associated with HSV-1 manifestations by Stock C1, Guillén-Grima F, de Mendoza JH, Marin-Fernandez B, Aguinaga-Ontoso I, Krämer A(PubMed)
(5) Herpes simplex virus, Key Fact by WHO
(6) Now playing: Viral plaque formation by Virology Blog

* Caffeinated Coffee, The Liver Protective and Anti Non Alcoholic Liver Disease Beverage

By Kyle J. Norton

Habitual caffeinated coffee intake may have a potential of curing Non Alcoholic Liver Disease, some scientists found.

Non-alcohol fatty liver disease (NAFLD) is a chronic medical condition of fatty liver caused by excessive fat deposited (steatosis) in the liver other than over consumption of alcohol.

The disease is a common liver disorder found in most developed countries, probably due to over consumption of carbohydrates which are considered as a major stimulus for hepatic de novo lipogenesis (DNL), the esterification of plasma free fatty acids, such as American diet.

According to clinical assessment conducted by the joint study lead by the Global Clinical Research, " Hepatic de novo lipogenesis(DNL), the synthesis of new fatty acids from non-lipid sources, is thought to play a pivotal role in the development of NAFLD"(4).

In compared to lipids that were defined as soluble substances in organic solvents, including the various types of fatty acids, eicosanoids, fatty alcohols, fatty aldehydes, ...... and hydrocarbons, fatty acids from non-lipid sources are men make substances that do not rely on organic solvents, but use other chemicals to separate the lipids from the rest of the food, including butter milk fat, beef fat (tallow, suet), chicken fa,t cream pork fat, (lard),... and stick margarine

Dr. Paglialunga S. the lead author suggested as of today, there is no NAFLD-specific therapeutic agent available. However, pharmaceutical drugs aimed at reducing hepatic fat accretion may prove to be a powerful ally in the treatment and management of this disease(4).

Some researchers also said, a chronic metabolic derangement referred as steatosis are directly associated to patients with obesity and type 2 diabetes(4).

According to the statistic, approximately, 80 millions of US adults suffer from Non-alcoholic fatty liver disease (NAFLD) in which 30% to 40% of those patients show no visible signs and symptoms.

However, most patient with Non Alcoholic Liver Disease may experience signs and symptoms of abdominal swelling, enlarged blood vessels just beneath the skin's surface, spleen, red palms,.... and jaundice as a result of liver advanced scarring (steatohepatitis and cirrhosis).

If you have some of above symptoms, please see your doctor right the way to rule out the possibility.

Coffee, second to green tea, is a popular and social beverage all over the world, particular in the West, made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.

According to a retrospective cross-sectional study on patients with non-alcoholic fatty liver disease (NAFLD), hepatitis C virus (HCV), and hepatitis B virus (HBV) infection to determine the effects of coffee intake on a non-invasive marker of liver fibrosis, coffee intake of 2 or more cups per day demonstrated a significant reduced liver symptom of stiffness, after adjustment for age, gender, smoking, alcohol consumption, in compared to other subgroups.

Additionally, in the review of epidemiological and clinical evidence by the Zhejiang University, researcher suggested coffee intake may have a profoundly reduced severity and risk of non-alcoholic fatty liver disease (NAFLD) prevalence.

In fact, the effect of coffee in attenuated risk of non-alcoholic fatty liver disease (NAFLD) incidence may be also involved other chemical constituents other than caffeine.

Dr. Chen S, the lead researchers suggested that said, "Several possible mechanisms underlying coffee's hepatoprotective effects in NAFLD include antioxidative, anti-inflammatory, and antifibrotic effects".


Interestingly, the review of literature published in database of Medline and Embase up to March 2015, showed that coffee and coffee caffeine intake have a strong impact in protect liver against complications of fibrosis incidence.

Information collected indicated that coffee and coffee caffeine intake have an enormous demonstration in ameliorated risk and symptoms of Non alcoholic liver disease, but some researchers suggested that other components may also play an important role in enhancement of these results.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Coffee Intake Is Associated with a Lower Liver Stiffness in Patients with Non-Alcoholic Fatty Liver Disease, Hepatitis C, and Hepatitis B by Hodge A1,2, Lim S3, Goh E4, Wong O5, Marsh P6, Knight V7, Sievert W8,9, de Courten B10.(PubMed)
(2) Coffee and non-alcoholic fatty liver disease: brewing evidence for hepatoprotection? by Chen S1, Teoh NC, Chitturi S, Farrell GC.(PubMed)
(3) Coffee and tea consumption in relation with non-alcoholic fatty liver and metabolic syndrome: A systematic review and meta-analysis of observational studies by Marventano S1, Salomone F2, Godos J3, Pluchinotta F4, Del Rio D5, Mistretta A1, Grosso G6.(PubMed)
(4) Clinical assessment of hepatic de novo lipogenesis in non-alcoholic fatty liver disease by Sabina Paglialunga1 and Clayton A. Dehn(PubMed)

* Chamomile Tea, The Herbal Tea That Works Better Than Sleeping Pills, With No Side Effects, Scientists Said

By Kyle J. Norton, Master of Nutrition

Intake of chamomile may have a strong and positive effect in prevented and treated insomnia, some scientists suggested.

Insomnia is a chronic sleep disorder characterized by difficulty of falling sleep and/or staying asleep. The condition affects most of the population of older adults due to hormones change that are associated to aging.

Most adults have experienced insomnia sometimes in their life. According to statistic, more than 30% of the population suffers from insomnia, one in three people suffer from some form of insomnia during their lifetime and women suffer from insomnia more often than men.

Some researchers suggested that psychiatric and medical conditions, unhealthy sleep habits,and in healthy diet and life style, particularly in use of substances, and/or certain biological factors are major causes of insomnia onset.

Some women in certain stages of menstrual  cycle also suffer from this type of sleep disorder, due to the body inability to cope with sudden change of hormone production. Needless to say,  insomnia that is caused by menstrual pain. According to the National Sleep Foundation poll, 33% of women said, their sleep is disturbed during their menstrual cycles.

In Australia, according to statistic produced by Virtual Medical Center, "Almost 90% of Australians suffer from a sleeping disorder, with 30% experiencing a severe sleeping disorder" and  "There are over 70 different defined sleep disorders which result in reduced sleep quantity or reduced sleep quality"(4).

Poor sleep quality in patients who suffer from insomnia may induce symptoms of fatigue, irritability, decreased memory and concentration,..... and malaise.

These results truly have a strongly negative impact on quality of life and work life, resulting in decreasing productivity and increasing absenteeism.

Use of sleep pill to treat insomnia may be effective, however, according to the Additive Center, "The dangerous effects of sleep medications range from seizures to depressed breathing. Some people also experience allergic reactions from sleeping pills that can cause difficulty breathing, chest pain, nausea and swelling" and "Though rare, people who use sleeping pills may even develop parasomnias. Parasomnias are defined as sleep disorders that include behaviors like sleep-walking, sleep-eating, sleep-sex, sleep-driving and other potentially dangerous sleep-related activities"(5).

Chamomile is also known as camomile, common name of many species daisy-like plants in the family Asteraceae.

The herb has been used in traditional medicine as antispasmodic and anti-inflammatory constituents and to treat menstrual cramps and sleep disorders, reduce cramping and spastic pain in the bowels, relieve excessive gas,..... and bloating in the intestine.

Ingredients
Guaianolides matricarin and achillin, acetoxyachillin and leucodin (= desacetoxymatricarin), corresponding C-11 stereoisomers(a),(Z)-2-β-d-glucopyranosyloxy-4-methoxycinnamic acid (cis-GMCA), chlorogenic acid, (E)-2-β-d-glucopyranosyloxy-4-methoxycinnamic acid (trans-GMCA), quercetagetin-7-O-β-d-glucopyranoside, luteolin-7-O-β-d-glucoside, apigenin-7-O-β-d-glucoside, chamaemeloside, apigenin 7-O-(6″-O-acetyl-β-d-glucopyranoside), apigenin] and one polyacetylene (tonghaosu)(b).

Chamomile, is one of most popular herb used for sleep disorders in herbal medicine. 

According to the Dr. Srivastava JK and research team at the Case Western Reserve University, in the investigation of The dried flowers of chamomile containing many terpenoids and flavonoids that may contribute to its medicinal properties, found that, injection in form of herbal tea, consumed more than one million cups per day worldwide, may have a significant impact in treatment of insomnia(1).

In the concerns of chamomile's (Matricaria recutita) efficacy and safety for treating chronic primary insomnia, scientists at the University of Michigan conducted an experiment of 34 patients aged 18-65 years with DSM-IV primary insomnia for ≥ 6-months, showed that application of 270 mg of chamomile twice daily or placebo for 28-days exerts a modest benefits of daytime functioning and mixed benefits on sleep diary(2).

Dr. Zick SM, the lead author at the end of the evaluation, said, "Chamomile did show modest advantage on daytime functioning, although these did not reach statistical significance. Effect sizes were generally small to moderate (Cohen's d ≤ 0.20 to < 0.60) with sleep latency, night time awakenings, and Fatigue Severity Scale (FSS), having moderate effect sizes in favor of chamomile"(2).

  The efficacy of chamomile in treatment of insomnia may also be attributed to the anxiolytic or sedative properties in improvement of sleep, according to the study of traditionally endowed with anxiolytic or sedative properties,(3).

However, Dr. Wheatley D suggested, " it's slow onset of effect (2-3 weeks) renders it unsuitable for short-term use (i.e. 'jet-lag'), but it does have profound beneficial effects on sleep architecture (augments deep sleep) that may make it particularly suitable for long-term use and for the elderly"(3).

The findings suggested that chamomile may be used as functional food to improve insomnia due to the procession of anxiolytic or sedative properties.


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Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
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Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
References
(a) Guaianolides and volatile compounds in chamomile tea by Tschiggerl C1, Bucar F.(PubMed)
(b) Quantitative determination of phenolic compounds by UHPLC-UV-MS and use of partial least-square discriminant analysis to differentiate chemo-types of Chamomile/Chrysanthemum flower heads by Avula B1, Wang YH, Wang M, Avonto C, Zhao J, Smillie TJ, Rua D, Khan IA.(PubMed)
(1a) Anxiety disorder(Canadian mental health association)
(1) Chamomile: A herbal medicine of the past with bright future by Srivastava JK1, Shankar E, Gupta S.(PubMed)
(2) Preliminary examination of the efficacy and safety of a standardized chamomile extract for chronic primary insomnia: a randomized placebo-controlled pilot study by Zick SM1, Wright BD, Sen A, Arnedt JT.(PubMed)
(3) Medicinal plants for insomnia: a review of their pharmacology, efficacy and tolerability. by Wheatley D.(PubMed)
(4) Insomnia by Virtual Medical Center
(5) Signs of Sleeping Pill Abuse by the Additive Center

* Avocado, The Prominent Fruit That Arrests Prostate Cancer Cells Cycle Division

By Kyle J. Norton, Master of Nutrition

Scientists may have  found a popular fruit that has a profound and positive effect in prevention and treatment of prostate cancer, some studies suggested.

Prostate cancer is a medical and chronic disease characterized by cells growth disorderly and uncontrollably in the tissue of prostate gland. At the later stage, cancerous cells may travel a distance away from the prostate gland to infect other healthy tissue and organs.

According to statistic in US, 1 in 9 men will be diagnosed with prostate cancer during his lifetime. Approximately, 6 cases out of 10 diagnosed with the condition are men aged 65 or older.

In 2017, 21,300 men in Canada were diagnosed with prostate cancer which represents 21% of all new cancer cases in men. And 4,100 men died from the disease(4).

Although Inherited mutations such as BRCA1 and BRCA2 that cause abnormal cell growth in the prostate gland are considered a major cause of prostate cancer, Acquired gene mutations such as over production of androgens (male hormones) gene that promote prostate cell growth also contribute to prostate cancer risk in some men.

However, over years of studies also suggested that  increases of age, ethnic group, family history, obesity, environment chemical,.... and unhealthy diet are also have a strong implication in induction to the onset of prostate cancer. 

Due to the slow progression of the disease, most patients do not experience any symptoms until the advance stage. Most common symptoms including blood in urine (hematuria), burning or pain during urination, difficulty urinating, decreased flow or velocity of urine stream, ......more frequent urges to urinate at night. 

In some cases, patients may also be loss of bladder control. 

If you experience some of above symptoms, please check with your doctor immediately to rule out the possibility.

Avocados are a commercially valuable fruit cultivated in tropical climates throughout the world.

The fruit has a green-skinned, pear-shaped fruit that ripens after harvesting, native to the Caribbean, Mexico, South America and Central America, belonging to the flowering plant family Lauraceae.


Chemical constituents
The fruit contains campesterol, high amounts of β-sitosterol; fatty acids (approximately 60% monounsaturated, 20% saturated, and 20% unsaturated); high amounts of glutathione (27.7 mg/100 g); approximately 2% protein; 6–9% carbohydrates and sugars (glucose, fructose, d-mannoheptulose, a taloheptulose, and an alloheptulose); two bitter substances (1-acetoxy-2,4-dihydroxyheptadeca-16-ene and 1,2,4-trihydroxyheptadeca-16-ene); carnitine; proanthocyanidins; persenones A and B(a).

According to the Case-control study of 209 men 40-80 years old with newly diagnosed, histologically confirmed prostate cancer and 226 cancer-free men attending the same urology clinics conducted by the University of the West Indie, intake of dietary MUFA from whole fruit of avocado are associated to reduced risk and treatment of prostate cancer(1).

Dr. Jackson MD, the lead scientist said, "Whole-blood and dietary MUFA reduced the risk of prostate cancer. The association may be related to avocado intakes. High blood linolenic acid was directly related to prostate cancer" and " Dietary intakes of other fats were not associated with PCa"(1).

The University of California study showed that the anti prostate cancer effects of avocado are not attributed to a single ingredient such as carotenoids (zeaxanthin, alpha-carotene, and beta-carotene), lutein but the interaction of all ingredients in the whole fruit in combination with other det-derived phytochemicals(2).

The study suggested, intake of avocado stimulated the increase production of increase in p27 protein which involves function as tumor suppressor in controlling the cell cycle progression, in incubated PC-3 cells(2)

Avocado induced PC- 3 cancer cell death through cells apoptosis through G(2)/M cell cycle arrest the study continued(2).

In the evaluation of the anti cancers effect of avocado conducted by the Purdue University study also showed a positive effect of the whole fruit in inhibition of six human tumor cell lines in culture, including human prostate adenocarcinoma (PC-3) cells(3).

The newly isolated Compounds 3 form of avocado containing g 1,2,4-triol moiety and a long aliphatic chain that terminates as either an alkane, alkene, or alkyne, respectively, exerted a strongest activity against PC-3 in comparable to adriamycin, an anti-cancer conventional medicine(3).

Furthermore, when tested against yellow fever mosquito larva, the 3 form avocado also was more effective than rotenone, a natural botanical insecticide(3).

Therefore, men who are at high risk of prostate cancer may want to add a portion of avocado into their daily diet for preventive measure.

Taken altogether, avocado with abundant carotenoids (zeaxanthin, alpha-carotene, and beta-carotene), lutein may be considered as functional food for prevention and treatment of prostate cancer.

However, additional large sample size and multi center clinical trials with human consumption during the course of the disease are necessary to re confirm avocado anti prostate cancer possibility.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
References
(a) Leung's Encyclopedia of Natural Ingredients:Chemical Composition of Avocado
(1) Associations of whole-blood fatty acids and dietary intakes with prostate cancer in Jamaica by Jackson MD1, Walker SP, Simpson-Smith CM, Lindsay CM, Smith G, McFarlane-Anderson N, Bennett FI, Coard KC, Aiken WD, Tulloch T, Paul TJ, Wan RL.(PubMed)
(2) Inhibition of prostate cancer cell growth by an avocado extract: role of lipid-soluble bioactive substances. by Lu QY1, Arteaga JR, Zhang Q, Huerta S, Go VL, Heber D.(PubMed)
(3) Cytotoxic and insecticidal constituents of the unripe fruit of Perseaamericana by Oberlies NH1, Rogers LL, Martin JM, McLaughlin JL.(PubMed)
(4) Prostate cancer statistics, Canadian Cancer Society
12. Avocado and Skin health
13. Avocado and Cadiovascular diseases