Holistic Health Articles and Research Related to Herbal Medicines, Foods and Phytochemicals

Wednesday, 17 January 2018

Alternative Therapy: Yoga in Reduced Blood Glucose Levels in Gestational Diabetes and Improved Pregnancy Outcome

Kyle J. Norton

Yoga intervention may have a profound and positive impact in reduced risk and treatment on blood sugar levels among pregnant women, the Prince of Songkla University study suggested.

Yoga, the ancient technique for harmonized external and internal body well beings, through breath control, meditation, bodily movement and gesture..... has been best known for people in Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

In a randomized controlled trial carried out to measure the capillary fasting plasma glucose, 2-h postprandial blood glucose, and hemoglobin A1c, among pregnant women with GDM, after accounting to other co founders, researchers indicated that fasting plasma glucose and 2-h postprandial blood glucose significantly reduced and glycosylated hemoglobin (HbA1c), accepted as an indicator for evaluation of the glucose control in diabetes mellitus (DM) patients also decreased substantially.

In deed, yoga mindfulness program created a self consciousness between body and mind, by bring back the presence and dealing the event positive way. In pregnant women the exercise induced attention of eating control such as when the stomach is full and what portion is needed. The breathing exercises relaxed the central nervous system, thus ameliorating stress expression in stimulated production of hormone epinephrine which is found to associate to blood sugar levels by converting glycogen from glucose stored in muscle cells and liver.

Prolonged stress may induce failure of the adrenal gland leading to over production of stress hormone in induction of abnormal high blood glucose.

Dr. Youngwanichsetha S, the led researcher said, "Mindfulness eating and yoga exercise had health benefits on glycemic control in pregnant women with GDM".

Additionally, in the support of the above differentiation, researchers at the SVYASA University conducted a study of 68 high-risk pregnant women recruited from two maternity hospitals in Bengaluru, India and randomized into yoga and control groups. with the yoga group (n=30) received standard care plus one-hour yoga sessions, three times a week, from the 12th to the 28th week of gestation and control group (n=38) received standard care plus conventional antenatal exercises (walking) in the same period, researchers found that yoga group expressed a significantly fewer pregnancy induced gestational diabetes (GDM) and cases in compared to control and induced less complications in yoga group, including small for gestational age (SGA) babies and newborns with low APGAR scores.

Truly, breathing and meditation practice in yoga were found to induce a strong implication of relaxation and oxygenation to the pancreas, thus increasing the pancreas function in regulation of blood glucose through insulin secretion.

Some yoga instructors also suggested that mindfulness in yoga lesson also improved blood sugar levels by bring back the natural state of self conscientiousness of present experience of more aware of hunger and satiety cues, and emotional impact on hunger, particularly enhanced more positive relationship and feeling to food.

After examining other risk factors, the study concluded, yoga only can reduced risk of unfavorable complications, including gestational diabetes mellitus in this group of women but also demonstrated significantly improvement of pregnancy outcome.

More importantly, in the searching of the data base from PubMed, eight studies (10 reports) satisfied the criteria included in the final analysis, researcher postulated that yoga intervention not only reduced risk of gestational diabetes mellitus, also improved pregnancy related complications, such as hypertension, and intrauterine growth restriction, particularly, decrease in perceived stress levels.

Taking altogether, Yoga therapy not only reduced risk of gestational diabetes mellitus in healthy women and improved glucose levels in women with gestational diabetes mellitus but also enhanced pregnancy outcome.

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) The effects of mindfulness eating and yoga exercise on blood sugar levels of pregnant women with gestational diabetes mellitus by Youngwanichsetha S1, Phumdoung S2, Ingkathawornwong T3.(PubMed)
(2) The effects of yoga in prevention of pregnancy complications in high-risk pregnancies: a randomized controlled trial by Rakhshani A1, Nagarathna R, Mhaskar R, Mhaskar A, Thomas A, Gunasheela S.(PubMed)

Herbal Therapy: Green Tea in Ameliorated Risk and Prevented Onset of Intestinal Ischemia

Kyle J. Norton

Green tea may have a therapeutic and positive effect in reduced risk and treatment of intestinal ischemia, some scientists suggested.

Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world. However, as yin in nature herbal medicine or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory.

Intestinal ischemia is a serious medical condition characterized by reduced blood flow to the

intestines.

In the evaluated 3 groups of male rats ramdonly assigned to Group I (ischemia-reperfusion,I/R) underwent I/R of the intestine (30 min of ischemia followed by 1 h of reperfusion). Group II (green tea + I/R) was given green tea for 2 wk before inducing I/R. Group III (control) with sham I/R, researchers found that injection of green tea group showed an impressive restoration of intestinal mucosa in compared to ischemia-reperfusion (I/R) group.

In observation of cellular antioxidant profile (superoxide dismutase and catalase), green tea group expressed a significant improvement of antioxidants similarly to those of group III and in compared to group II.

The expressions of cellular proliferation markers (proliferating cell nuclear antigen and Ki-67) in regulated intestinal cell division and proliferation were also increased by green tea application..

The above illustration indicated that long term intake of green tea injection may exhibit a strong protection against the intestinal mucosa from injury.

Further differentiation of the effect of Quercetin, the bioactive substance of tea against experimental ischemia- reperfusion (IR) injury of the small intestine in rats, found that quercetin administrated intraperitoneally 30min before 1h ischemia of superior mesenteric artery with following reperfusion periods lasting 1, 4 and 24h significant decreases cyclooxygenase-2 (COX-2) enzyme in the epithelial lining of the intestinal villi in expression of normal cell apoptosis only during 24h of reperfusion in a late phase of IR injury in comparison with the control group.

According to the observation of the morphology of COX-2 positive cells, COX-2 positivity was found particularly in goblet cells with function in secreted the main component of mucus.of the intestinal villi epithelium and enteroendocrine cells found in the wall of the gut that secrete hormones that regulate glucose levels, food intake, and stomach emptying respectively, in the glandular epithelium in the group I mice in compared to significantly lesser levels in green tea group.

Dr. Tóth Š, the lead authors at the joint study said," quercetin application attenuated mucosal damage from IR injury by inhibiting neutrophil infiltration which was demonstrated by a lower number of myeloperoxidase positive cells in the lamina propria".

In other similar study with male specific pathogen-free (SPF) Charles River Wistar rats were used in the experiment with quercetin administered intraperitoneally 30min before 1h ischemia of superior mesenteric artery with following 24h lasting reperfusion period., researchers at the joint study lead by the Pavol Jozef Safarik University, also indicated that application of quercetin increases the production of anti inflammatory cytokine IL10 observed by analysis of the blood sample and jejunal tissue and in the number of CD68-positive cells in the lamina propria mucosae (p<0.001) in initiation of production of new blood vessels growth and inflammatory mytokines in compared to control group.

Dr. Curgali K, the lead authors, after taking into account of other con-founders, said, "the preventive application of quercetin before induction of jejunal IRI stimulates faster jejunal mucosa restoration and it seems to have immunomodulatory and anti-inflammatory effects" and "CD68-positive macrophages could have crucial role in this process since they work as both growth factor and cytokine producers".

Taken together, green tea with abundant bioactive phytochemicals such as quercetin may be considered as a functional food in reduced risk and prevented onset of intestinal ischemia. People with high risk in development of intestinal ischemia may consider to add 1 or 2 cups of green tea into their daily diet.

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA For Women

Sources
(1) Protective effects of green tea on intestinal ischemia-reperfusion injury by Abdeen SM1, Mathew TC, Dashti HM, Asfar S.(PubMed)
(2) Quercetin attenuates the ischemia reperfusion induced COX-2 and MPO expression in the small intestine mucosa by Tóth Š1, Jonecová Z1, Čurgali K1, Maretta M2, Šoltés J1, Švaňa M1, Kalpadikis T1, Caprnda M3, Adamek M4, Rodrigo L5, Kruzliak P6.(PubMed)
(3) Quercetin protects jejunal mucosa from experimental intestinal ischemia reperfusion injury by activation of CD68 positive cells by Curgali K1, Toth S1, Jonecova Z1, Maretta M2, Kalpakidis T1, Petriskova I1, Kusnier M1, Soltes J1, Svana M1, Caprnda M3, Delev D4, Rodrigo L5, Mechirova E1, Kruzliak P6.(PubMed)

Tuesday, 16 January 2018

Herbal Therapy: Green tea In Modulated Fat Metabolism

Kyle J. Norton

Green tea may have a therapeutic and positive effect in reduced abnormal fat metabolism, some scientists suggested.

Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world. However, as yin in nature herbal medicine or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory.

Fat metabolism is a biological process converted lipid intake to energy for the body needs through breaking down fat into glycerol and fatty acids before being absorbed by the intestines.

In the evaulation of the mechanisms of actions of EGCG on bile acid homeostasis and lipid metabolism of green tea bioactive polyphenol (-)-epigallocatechin-3-gallate (EGCG), researchers conducted a study included male C57BL/6J mice fed with a low-fat diet, a high-fat western-style diet or a high-fat western-style diet containing 0.32% green tea bioactive polyphenol (-)-epigallocatechin-3-gallate (EGCG), found that at 17 weeks of experiment, mice group fed with EGCG exhibits a strong effect in reduced body weight gain, mesenteric fat mass, serum cholesterol and severity of fatty liver.

Additional analysis indicated that green tea reduced expression above parameters was a result of significantly elevated the mRNA levels of cholesterol 7α-hydroxylase initiated by cholesterol in inhibition of bile acid synthesis in cholesterol metabolism, thus attenuated absorption of lipid.

Injection of green tea EGCG also increased the level of HMG-CoA reductase in inhibited cholesterol synthesis, biliary lipid secretion, and elevated blood cholesterol through activation of low-density lipoprotein receptors which play an important role of limiting step in lipid synthesis.

Moreover, green tea EGCG also elevated scavenger receptor class B type 1 (SRB1) with functions as a receptor for high-density lipoprotein in meditating the uptake of HDL-derived cholesterol and cholesteryl ester in the liver as well as modulating and regulating certain pathways and networks involved cellular lipids in biological systems.

Dr. Huang J, the lead scientist in the joint study at the State University of New Jersey, said, "The intestinal bile acid content was significantly decreased by EGCG, while fecal excretion of bile acids, cholesterol and total lipids were increased" and "EGCG decreases bile acid reabsorption, results in lower intestinal bile acid levels, which further decreased the absorption of lipids".

Further differentiation of the green tea effect to examine the on lipid levels associated with obesity in C57BL/6J mice fed a normal diet (ND), HFD and HFD with GT for 12 weeks, group with green tea extract and HFD expression a significant alternation of levels of several lipid metabolites observed by the partial least squares discriminant analysis score plot.

Mice group fed with high fat diet demonstrated decreased levels of lysophospholipids (LPLs) (lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine) which show a negative correlation with triglyceride hydrolysis and increased fat absorption in compared to normal diet group. These alternations were not found in mice group fed with HFD plus green tea.

Alternation of lysophospholipid was associated to substantial impact on lysophospholipid metabolism, in contribution of the onset or progression of obesity.

The restoration of lysophospholipids (LPLs) by green tea extract caused by long term high fat diet may be an indication of how green tea reduced expression of inflammation, insulin resistance, and fatty liver disease in obesity.

Interestingly, in the observation of injection of green tea extract in the regulation of hepatic fat metabolism in 36 male chickens fed GTPs at a daily dose of 0, 80 or 160 mg/kg of body weight for 4 weeks, researchers at the joint study lead by the Anhui Agricultural University, suggested that oral administration of green tea polyphenols (GTPs) significantly improves lipid metabolism through reduced hepatic lipid content and abdominal fat mass and abdominal fat mass accumulation which were correlated to onset and progression of over weight and obesity.

Additionally, the application also expressed a strong effect in the phosphorylation levels of AMP-activated protein kinase α (AMPKα) which play an important role in skeletal muscle fatty acid utilization and in regulating growth and reprogramming metabolism, and Acetyl-CoA carboxylase 1 (ACACA) in modulation of fat cell cycle stages and cytokinesis, thus reducing fat synthesis and production of pro inflammatory cytokines.

More importantly, green tea polyphenol also altered the mRNA levels and enzymatic activities in suppressed expression of enzymes involved PUFA in the liver in stimulated lipid synthesis and fat oxidation.

Taken together, green tea containing high amount of bioactive polyphenols, such as catechins may be considered as a functional food to reduce onset and progression of over weight and obesity. However, intake of green tea extract should be taken with care as acute liver toxicity has been reported in some cases.

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA For Women

Sources
(1) Green Tea Polyphenol EGCG Alleviates Metabolic Abnormality and Fatty Liver by Decreasing Bile Acid and Lipid Absorption in Mice by Huang J1,2, Feng S1,3, Liu A1, Dai Z1,4, Wang H1, Reuhl K5, Lu W6, Yang CS1,2.(PubMed)
(2) Effect of green tea on hepatic lipid metabolism in mice fed a high-fat diet by Nam M1, Choi MS2, Choi JY2, Kim N3, Kim MS3, Jung S1, Kim J1, Ryu DH4, Hwang GS5.(PubMed)
(3) Green tea polyphenols alter lipid metabolism in the livers of broiler chickens through increased phosphorylation of AMP-activated protein kinase by Huang J1,2, Zhou Y1, Wan B1, Wang Q1, Wan X1,2.(PubMed)
(4) Increase in serum and bile cholesterol and HMG-CoA reductase by lovastatin in rats by Yamauchi S1, Linscheer WG, Beach DH.(PubMed)

Alternative Therapy: Yoga Intervention in Reduced Pregnancy Discomforts in All Aspects

Kyle J. Norton

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By Ancient African Red Tea Recipe & Its Fat Melting Powers

Yoga intervention may have a profound and therapeutic effect in reduced pregnancy discomfort, epidemiological studies suggested.

People who participated in yoga class are likely to experience less or lower levels of anxiety, a renowned study suggested.

Yoga, the ancient practical technique for harmonized external and internal body well beings, through breath control, meditation, bodily movement and gesture..... has been best known for people in Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

In the study of target population primigravidas at 26-28 weeks of gestation (no high-risk pregnancies) who had not engaged in regular exercise or yoga for at least one year to evaluate the acute effect of yoga therapy in risk of pregnancy discomforts with 88 individuals; 43 in the control group and 45 in took part in the prenatal yoga program with duration of the prenatal yoga program of 12-14 weeks, and at least three sessions per week, researchers found that women in the prenatal yoga program group expressed a significantly fewer pregnancy discomforts in compared to the control group at the at 38-40 weeks of gestation, particularly, in the outcome and self-efficacy expectancy during the active stage of labor and second stage of labor.

In deed, pregnancy physical discomfort such as morning sickness fatigue, breast tenderness, constipation,...... and psychological discomforts such as “Rollercoaster” emotions, anxiety, depression are either results of hormone change and increased stress levels during pregnancy.

Yoga as an integrated form of exercise with slow breathing method and mediation ameliorated stress expression by created a self consciousness between body and mind, relaxed the central nervous system in reducing psychological discomforts and dealing the physical discomforts in the positive way.

Further more, maternal yoga practice also reduced stress in induction of anxiety, worries and fear at 38-40 weeks of gestation and during the active stage of labor and second stage of labor through mind and body relaxation in bring back the presence of expectant motherhood in a naturally conscious way.

Some researchers also suggested that maternal yoga participation such as postures and stretch not only alleviates anxiety around labor but also increases strength in the legs to prepare for the date of labor.

Dr. Yi-Chin Sun, the led author said, "the provision of booklets and videos on yoga during pregnancy may contribute to a reduction in pregnancy discomforts and improved childbirth self-efficacy" and can be used by health-care professionals as an evidence-based intervention.

Interestingly, with an aim to improve Pregnancy discomfort and outcome, researchers at the joint study led by the St. John's Medical College and Hospital, Bangalore conducted a study to assess yoga therapy (YT) module on maternal stress level in high risk pregnancy of sixty-eight pregnant women (38 in the control group with standard antenatal care and 30 in the YT group) with 27.2 (5.2) years of mean age from the outpatient services of medical college and hospital in Bangalore, South India, opinionated that by the observation of the Perceived stress scale (PSS), yoga intervention group demonstrated a significantly fewer pregnancy discomforts at the second follow-up (28th week of pregnancy) compared to the control group who experienced an increased stress level.

Some women at the 28th weeks of gestation may experience certain psychological symptoms such as anxiety, insomnia, emotional distress,... and physical symptoms of constipation, continued weight gain, heartburn, swelling in limbs, backaches and leg cramps,.....ension

In psychological symptoms, physical postures, breathing, relaxation, and meditation have shown to calm the nervous tension in bring back the self consciousness and increased the women the ability in maintaining positive feelings or in regulating stress feelings, thus attenuating the symptoms of anxiety, insomnia, emotional distress,... and dealing the physical symptoms in profound manner.

Dr. CS Deshpande, the led author, after considering other risk factors said, "YT module can decrease the stress level during high-risk pregnancy complications" and "practicing YT during high-risk pregnancy is not only a cost-effective option but also a feasible and safe option".

In the support of the above differentiation, the Eastern Virginia Medical School launched a study by searching the literature published online of PubMed database from January 1970 to January 2011, out of many studies reviewed, five prospective observational studies (n = 575) and three randomized clinical trials (RCTs; n = 298) met the criteria and guideline selected, researchers after analysis each study individually, suggested that all nonrandomized trials indicated a significant reduction of pregnancy symptoms and complications particularly in pregnancy discomforts and all randomized trials suggested that participated yoga during pregnancy can significantly lower pain and discomfort (p < 0.05) and perceived stress (p = 0.001) and improve quality of life in physical domains

Taking altogether, yoga practicing during pregnancy may be considered as an integrated from of exercise combined with standard care treatment in reduced pregnancy discomforts, especially in high risk women.

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299

Sources
1. Effects of a prenatal yoga programme on the discomforts of pregnancy and maternal childbirth self-efficacy in Taiwan by Sun YC1, Hung YC, Chang Y, Kuo SC.(PubMed)
(2) Yoga for high-risk pregnancy: a randomized controlled trial by Deshpande CS1, Rakhshani A, Nagarathna R, Ganpat TS, Kurpad A, Maskar R, Nagendra HR, Sudheer DC, Abbas R, Raghuram N, Anura K, Rita M, Ramarao N.(PubMed)
(3) Yoga during pregnancy: a review by Babbar S1, Parks-Savage AC, Chauhan SP.(PubMed)

Monday, 15 January 2018

Herbal Therapy: Green Tea In Ameliorated Risk, Progression and Treatment of Liver Fibrosis

Kyle J. Norton

Green tea may have a therapeutic and positive effect in reduced risk and treatment of Liver Fibrosis, some scientists suggested.

Green tea containingmore amount of antioxidants than any drink or food with the same volume, is the leaves of Camellia sinensis, undergone minimal oxidation during processing, originated from China.

Liver fibrosis is a liver disease with excessive accumulation of scar tissue as a result of inflammation and liver cell death

According to Fibro Test, approximately, the prevalence of advanced fibrosis was 2.8% in a general population aged 40 years or older.

According to the application of a novel bio-nano particle named 'Chitosan nano-encapsulated green tea extract' at the ultrastructural level on 25 adult rats induced liver toxicity by injection of carbon-tetrachloride and ethanol doses for 3 weeks, rats treated with novel substance expressed a significant reduction of nearly 25% of the sub-cellular area infected with hepatic fibrosis.

The efficacy of Chitosan nano-encapsulated green tea extract in decreased liver fibroids was attributed to the antioxidant activity in inhibited the expression of the injected chemicals in induction over production of reactive oxygen species (ROS) in chain reaction to elevated oxidative stress in initiation of liver cell apoptosis.

Observed by scanning electron microscopy, oral administration of novel bio-nano particle also exerted a strong free radical scavengers effect in protected against changes of cell surface structure and surrounding area between the hepatocytes, thus ameliorated risk of collagen deposit to cause liver fibroids.

Moreover, in carbon tetrachloride CCL4 induced fibrotic liver tissues in rat models, treatment of Green Tea Extract (GTE) encapsulated into Chitosan Nanoparties (CS-NPs) revealed that collagen fibers of 250 to 300 nm widths found in the fibrotic liver samples of control group with no treatment were cleared in green tea treatment group.

The effectiveness of GTE is reduced expression of collagen fibers in the liver a was found to correlate to the antioxidant expression in reduced CCL4 in induction of over production of free radicals in precipitated liver tissue damage.

Interestingly, in the evaluation of the protective effect of green tea extract (GT) on hepatic fibrosis in vitro and in vivo in dimethylnitrosamine (DMN)-induced rats, researchers at the Korea University, indicated that application of GT inhibited activated HSC-T6, a rat hepatic stellate cell line which is considered as the major cell type involved in liver fibrosis.

The application also attenuated the collagen deposition which are elevated and acted as a biomaker for progression of liver fibrosis, particularly, in expression of collagen type 1 formation of scar tissue in response to liver damage, found in the early event in the development of hepatic fibrosis, confirmed both by liver histology and by quantitative measurement of hepatic hydroxyproline content.

Dr. Kim HK, the lead author said, "green tea administration can effectively improve liver fibrosis caused by DMN, and may be used as a therapeutic option and preventive measure against hepatic fibrosis".

Taken together, green tea with abundant bioactive polyphenols may have a therapeutic and pharmaceutical effect in reduced risk, progression and treatment of liver fibroid caused by forming of scars as a result of liver damage through antioxidant activity.

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN

Sources
(1) Effect of Green Tea Extract Encapsulated Into Chitosan Nanoparticles on Hepatic FibrosisCollagen Fibers Assessed by Atomic Force Microscopy in Rat Hepatic Fibrosis Model by Safer AM, Hanafy NA, Bharali DJ, Cui H, Mousa SA.(PubMed)
(2) Quantification of the Healing Effect in Hepatic Fibrosis Induced by Chitosan Nano-Encapsulated Green Tea in Rat Model by Safer AM, Sen A, Hanafy NA, Mousa SA.(PubMed)
(3) Antifibrotic effects of green tea on in vitro and in vivo models of liver fibrosis by Kim HK1, Yang TH, Cho HY.(PubMed)

15 Health Benefits of Lentils

Kyle J. Norton

Lentil, type of pulse and tiny legume that can be cooked quickly and rich in protein and fiber is a bushy annual plant of genus Lens to the Fabaceae family, native to Middle East.

Lentils (Lens)

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Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Herbal Therapy: Herbal Catnip in Ameliorated Risk and Treatment of Lung Cancer

Kyle J. Norton

Catnip may have a potential and substantial effect in reduced risk and treatment of lung cancer, some scientists suggested.

Catnip is also known as catswort, or catmint, a plant of Nepeta, belonging to the family of Lamiaceae, native to Europe and Asia, use in herbal medicine as insect repellant and to treat digestive disorders, children restlessness and nervousness, fevers, cold and flu, skin irritations stimulate sweating, promote menstruation, etc..

Ingredients
Terpenoid nepetalactone, α-Pinene, β-Pinene, Cyclohexen-1-yl-methyl ketone, Triplal, Thymol, Nepetalactone, Nepetalactone, etc..

Lung cancer is medical condition characterized by irregular cell growth in the issues of lung. At the later stage, the cancerous cell may invade other healthy tissues and organs a distance away from the original site.

According to statistic, In 2015, approximately 26,600 Canadians will be diagnosed with lung cancer and 20,900 will die of it.

According to the investigation of the anti cancer effect of extracts isolated from catnip containing sub-fractions (ND-1-ND-15) of ND using human lung cancer cells (A-549) experiment, the selected sub-fractions of the chloroform extract demonstrated a significantly activity in reduced the cell viability of A-549 cells, through alternated the cancer cell structures and arrangement in a concentration-dependent manner.

In classification of the effect of each individual sub fraction researchers found that ND-10 fraction induces the greatest cytotoxicity in lowest dose in compared to other fractions with ND-1 does not cause any cytotoxicity even at higher concentrations.

In compared to other cancer cell lines, human lung cancer cells (A-549) was found to be more sensitive to the application of the extracts.

Further differentiation of the Nepeta cataria L. anti-cancer treatment effect recorded in the Chinese Pharmacopoeia of version 2015 and belongs to one of the Traditional Chinese medicine (TCM). Microfluidic chip technology, researchers at the joint study lead by the Liaoning University of Traditional Chinese Medicine conducted a study based on total flavonoid extracted from Nepeta cataria L. (TFS) on risk of human lung cancer cell line A549 using the microfluidic device and Flow Cytometry assays, suggested that the bioactive chemicals exert a significant activity in inhibited cancer cell proliferation and tumor progession and invasion through mRNA expression of MicroRNA-126 (miR-126) which plays an important role involved in post-transcriptional regulation of gene expression in inhibition of human cancer progression, regulating apoptosis of cancer cells.

Additionally, the anti lung cancer expression was attributed to ameliorate the vascular endothelial growth factor (VEGF), a potent angiogenic factor with function to trigger development of new blood vessel to supply nutrients and oxygen to ignite cancer cell proliferation and inhibited the expression of the PI3K signalling pathway which is correlated to the cancer aggression and invasive malignancy.

Researchers also indicated that according to the Flow Cytometry assay, the phytochemicals also exhibit the expression of PTEN (phosphatase and tensin homologue deleted on chromosome 10) PTEN gene in initiated tumor suppressible activity through expression PI3K-AKT pathway in induced cell cycle arrest or apoptosis in human cancer cells

Dr. Jiaxin Fan, the lead author, after taking into account of other confounders said, " Taking all these results into consideration we can draw a conclusion that TFS may be used as a novel therapeutic agent for NSCLC in the near future".

The information findings postulated that herbal catnip with abundant bioactive compounds may be considered as a function food in reduced risk and treatment of human lung cancer, depending to further differentiation.

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA FOR WOMEN

Sources
(1) Anticancer Activity of Chloroform Extract and Sub-fractions of Nepeta deflersiana on Human Breast and Lung Cancer Cells: An In vitro Cytotoxicity Assessment by Al-Oqail MM1, Al-Sheddi ES1, Siddiqui MA2, Musarrat J2, Al-Khedhairy AA2, Farshori NN1.(PubMed)
(2) Mechanism of modulation through PI3K-AKT pathway about Nepeta cataria L.’s extract in non-small cell lung cancer by Jiaxin Fan,#1 Yongrui Bao,#1,2,3,4 Xiansheng Meng,1,2,3,4 Shuai Wang,1,2,3,4 Tianjiao Li,1,2,3,4 Xin Chang,1 Guanlin Yang,1 and Tao Bo4(PMC)

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Wednesday, 17 January 2018

Alternative Therapy: Yoga in Reduced Blood Glucose Levels in Gestational Diabetes and Improved Pregnancy Outcome

Herbal Therapy: Green Tea in Ameliorated Risk and Prevented Onset of Intestinal Ischemia

Tuesday, 16 January 2018

Herbal Therapy: Green tea In Modulated Fat Metabolism

Alternative Therapy: Yoga Intervention in Reduced Pregnancy Discomforts in All Aspects

Monday, 15 January 2018

Herbal Therapy: Green Tea In Ameliorated Risk, Progression and Treatment of Liver Fibrosis

15 Health Benefits of Lentils

Herbal Therapy: Herbal Catnip in Ameliorated Risk and Treatment of Lung Cancer