Food therapy: Coffee and Coffee Caffeine In Attenuated Risk and Symptoms of Hepatic Steatosis

By Kyle J. Norton

Good news for coffee lovers, intake of coffee and coffee caffeine daily and regularly showed a significant impact in reduced risk and symptoms of hepatic steatosis incidence, a renowned institute study suggested.

Coffee, a popular and social beverage all over the world, particular in the West, is a drink made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.

Hepatic steatosis. a fatty liver disease caused by excessively accumulated amounts of triglycerides and other fats inside liver cells due several factors alcoholism, malnutrition, pregnancy, or drug therapy.

In the analyzed 1024 Japanese male workers in diagnosed of hepatic steatosis based on ultrasonography, participants divided coffee and green tea consumption into the following three categories: non-drinker; 1-2 cups/day and ⩾3 cups/day, after adjusting to other risk factors, researchers filed the following results
1. Out of 1024 patients, 25.9% were diagnosed with hepatic steatosis.
2. Patients drinking >3 cups of coffee/day displayed a significantly lower risk of hepatic steatosis in compared to non coffee drinker group.
3. Coffee intake reduced expression of lepitin, a protein produced by fatty tissue and believed to regulate fat storage in the body of moderate-severe hepatic steatosis groups.

Base on these results, researchers of the joint study lead by the Fukuoka University, insisted that coffee and coffee caffeine not only reduced risk of prevalence of hepatic steatosis but also improved liver function through decrease level of leptin in fat accumulation.

More importantly, in the study of aged C57 BL/6 NCr mice divided into three groups: controls that were not given coffee (n = 9), a group that received 0.1% caffeinated coffee (n = 9), and a group that received 0.1% decaffeinated coffee (n = 9) for 17 wk until mice reached the age of 24 months, researcher files the following reports
1. Regular and decaffeinated coffee consumption display a decreased plasma-free fatty acid levels and increased hepatic adenosine triphosphate content, an indication of reduced risk of hepatic steatosis
2. Coffee and coffee caffeine also reduced expression of protein content, responsible in fat acculation in the liver.
3. Coffee consumption in these aged population demonstrated a positive effect on behavioral energy and lipid metabolism as well.

More interestingly, Dr. Salomone F, the lead researcher at the joint study lead by the Azienda Sanitaria Provinciale di Catania, in the investigated coffee phytochemicals effect in reduced risk of liver diseases said, "in experimental models of fibrosis, caffeine was shown to inhibit hepaticstellate cell activation by blocking adenosine receptors, and emerging evidence indicated that caffeine may also favorably impact angiogenesis and hepatic hemodynamics" and " chlorogenic acids, potent phenolic antioxidants, suppress liver fibrogenesis and carcinogenesis by reducing oxidative stress and counteract steatogenesis through the modulation of glucose and lipid homeostasis in the liver".

Taking together, there is no doubt that coffee and coffee caffeine would have a significant and therapeutic effect in attenuated risk and complication of hepatic steatosis, through expression in reduced fat accumulation and lipid per oxidation in liver.

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Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Coffee but not green tea consumption is associated with prevalence and severity of hepatic steatosis: the impact on leptin level by Imatoh T1, Kamimura S2, Miyazaki M3.(PubMed)
(2) Coffee consumption in aged mice increases energy production and decreases hepatic mTOR levels byTakahashi K1, Yanai S2, Shimokado K3, Ishigami A4.(PubMed)

Food Therapy: Dried Peas and Beans In Reduced Risk and Treatment of Colon Cancer

Kyle J. Norton

Dietary factors can influence cancers formation and growth, intake of dried peas may have a potential effect in reduced risk of colon cancer, a recent study suggested

Dried pea is a small but nutritionally mighty member of the legume family, genus Pisum belongings to the family Fabaceae with healthy source of proteins, fibers, vitamins and minerals.

Colon cancer is a condition characterized by cell growth disorderly and irregularly in the tissues of colon.

In a case-control designed study of 186 men and women with a mean of 58 years of age revealed that consumption of legumes such as dried beans, split peas, or lentils daily and regularly was inversely associated with reduced risk of colon cancer, after adjusting all potential confounding variables.

The relative risk odd ratio of colon cancer occurrence in these subjects was ameliorated substantially in compared to control.

Researchers also indicated that risk colon cancer decrease may be attributed to legumes dietary fiber together with enormous presences of phytochemical compounds.

Dr. Agurs-Collins T, the led author said, "Nurses working with African-Americans should encourage consumption of these foods to decrease this risk".

Other, in the study of the same subject suggested that by modifying diet and lifestyle habits, adenomatous polyps and 25-35% of colon adenoma risk could be avoidable. As consumption of legumes at least 3 times/wk reduced the risk of colon cancer by 33% after adjusting for meat intake.

Furthermore, the research result also postulated that high frequency of consumption of cooked green vegetables, dried fruit, legumes, and brown rice was associated with a decreased risk of colorectal polyps.

Interestingly, in the investigated effect of consumption of standard diets supplemented with freeze-dried vegetables (peas, spinach, sprouts and broccoli) and carotenoids (all-trans beta-carotene and palm oil carotenoid extract) on surrogate end-point markers for colorectal cancer in an azoxymethane-induced rat model, researchers at the Unilever Research Vlaardingen, illustrated that
peas, spinach, sprouts and a mix of all vegetables diet expressed a significantly reduced the number of foci with >2 aberrant crypts/focus by 37, 26, 23 and 26%, particularly in the pea and spinach intervention groups.

After adjusting to other risk factors, researchers filed the following reports
1. Peas, spinach, sprouts and a mix of all vegetables diet was beneficial effects in reduced risk of colorectal carcinogenesis
2. Consumption of several types of vegetables inhibits early onset of colorectal carcinogenesis
3. and suggest that the vegetable-induced effect is more pronounced in advanced lesions.

Taking altogether,  dried peas may be used as therapeutic ingredients in reduced risk and treatment of colon cancer and diseases related to colon abnormalities.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Legume intake and reduced colorectal adenoma risk in African-Americans by Agurs-Collins T1, Smoot D, Afful J, Makambi K, Adams-Campbell LL(PubMed)
(2) Foods and food groups associated with the incidence of colorectal polyps: the Adventist Health Study by Tantamango YM1, Knutsen SF, Beeson WL, Fraser G, Sabate J.(PubMed)
(3) Effect of vegetable and carotenoid consumption on aberrant crypt multiplicity, a surrogate end-point marker for colorectal cancer in azoxymethane-induced rats by Rijken PJ1, Timmer WG, van de Kooij AJ, van Benschop IM, Wiseman SA, Meijers M, Tijburg LB.(PubMed)

Food Therapy: Coffee In Reduced risk of Acute Pancreatitis

By Kyle J. Norton


Intake of coffee and coffee caffeine daily and regularly may have a potential positively in reduced risk and treatment of pancreatitis, a Swede study suggested.

Coffee, a popular and social beverage all over the world, particular in the West, is a drink made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.

Pancreatitis is the inflammation of the pancreas. In most cases, the disease will go away without notice but  in serve cases, it may cause some complications.

In the examine data obtained from two prospective cohorts, the Cohort of Swedish Men and the Swedish Mammography Cohort, including 76 731 men and women (born 1914-1952) with assessment at baseline with a FFQ, and followed up between 1998 and 2012 via linkage to national health registries, researchers filed the following important results
1.During 1 035 881 person-years of total follow-up, there were 383 cases (246 in men and 137 in women) of incident non-gallstone-related acute pancreatitis out of 76 731 particioants.
2. Coffee intake regardless amounts was not associated to risk of non-gallstone-related acute pancreatitis.

The findings demonstrated only non risk of pancreatitis prevalence in coffee consumption without giving further detail of other aspects.

Further discussion of coffee intake in risk of pancreatitis, researchers at the joint study led by the University of Southern California described that dietary form an essential role in prevent or exhibition of pancreatitis. but coffee was one the beverage with protective effect in ameliorated risk of acute pancreatitis,

In the Multiethnic Cohort (age at baseline, 45-75 y) study with cases of pancreatitis identified using hospitalization claim files from 1993 through 2012 and categorized as having gallstone-related acute pancreatitis (AP) (n = 1210), AP not related to gallstones (n = 1222), or recurrent AP or suspected chronic pancreatitis (n = 378), out of many dietary products used in the study, coffee consumption scored a outstanding effect in reduced incidence of acute pancreatitis.

Further to support the efficacy of coffee in attenuated risk of AP, researchers at the Kaiser Permanente Medical Center, filed the below report after study of 129,000 prepaid health plan members with supplied data about demographics and habits in 1978-85 and 439 persons in this group subsequently hospitalized for pancreatitis,
1. Coffee intake showed a moderated effect in reduced risk of acute pancreatitis,
2. The relative risk of per cup per day coffee intake was 0.85 in compared to baseline
3. Risk of AP reduced linearly for numbers of cup intake daily
4. In compared to female with the additional factors, risk of AP was higher in male participants group.

Taking together, there is no doubt that coffee consumption may have a profound effect in reduced risk of acute pancreatitis probably through phytochemicals in coffee antioxidant and anti inflammatory activities. But further study are needed to confirm this findings.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) A prospective cohort study on the association between coffee drinking and risk of non-gallstone-related acute pancreatitis by Oskarsson V1, Sadr-Azodi O2, Orsini N1, Wolk A1.(PubMed)
(2) Dietary Factors Reduce Risk of Acute Pancreatitis in a Large Multiethnic Cohort by Setiawan VW1, Pandol SJ2, Porcel J3, Wei PC4, Wilkens LR5, Le Marchand L5, Pike MC6, Monroe KR4.(PubMed)

Food Therapy: Dried peas Water Soluble Fibers in Attenuated Risk of Hypercholesterolemia

Kyle J. Norton


Water soluble fibers found in dried peas may have potential effects in reduced risk of hypercholesterolemia, a joint universities study suggested.


Dried pea is a small but nutritionally mighty member of the legume family, genus Pisum belongings to the family Fabaceae with healthy source of proteins, fibers, vitamins and minerals.

Hypercholesterolemia is a condition characterized by abnormal high of total cholesterol in the blood stream.

According to study led by the University of California, dietary soluble fibers intake found in dried peas and other sources has been associated with health benefits in reduced lipid levels and other ailments.

In the review studies of literature published and related to the hypocholesterolemic effects of dietary soluble fibers and fiber-rich foods, researchers showed that
1. Daily consumption of water-soluble, viscous-forming fibers can reduce total and low-density lipoprotein cholesterol levels by about 5-10 %;
2. Observation of effect of dietary water soluble also expressed some minimal changes high-density lipoprotein cholesterol or triglyceride levels.
3. Types of soluble fiber and phytochemicals presented in the food also exerted different effects in cholesterol-lowering activities with medium to high molecular weight fibers were more effective.

Furthermore, in the 68 hyperlipidemic adults consumed a test (high-fiber) and a control low-fat (25% of energy), low-cholesterol (<150 mg/d) diet for 1 mo each, randomized crossover study with high-fiber diet included 4 servings/d of foods containing beta-glucan or psyllium that delivered 8 g/d more soluble fiber than in the control diet, researchers showed that high fibers dietary group expressed a reduced total cholestero, total:HDL cholesterol, LDL:HDL cholesterol and apolipoprotein B:A-I  in compared to control.

Also in comparison of both diets, there were no significant differences in palatability or gastrointestinal symptoms.

Dr. Jenkins DJ, the led author said, "The reduction in serum lipid risk factors for cardiovascular disease supports the FDA's approval of a health claim for a dietary fiber intake of 4 servings/d. Although relatively small in terms of patient treatment, the reduction in cardiovascular disease risk is likely to be significant on a population basis".

Finally, according to the University of Naples, the study of the effect of diet in lipid and glucose levels of diabetics indicated the following and interesting results

1. Dietary fiber has the ability to retard food digestion and nutrient absorption and certainly has an important influence on lipid and carbohydrate metabolism
2. Dietary also has a profound effect in influence of the accessibility of nutrients by digestive enzymes, thus delaying digestion and absorption.
Therefore,
3. the consumption of legumes, vegetables, and fruits--rich in water-soluble fiber--should be particularly encouraged i healthy and diabetics.

Dr. Riccardi G, the led author concluded " a diet low in cholesterol and saturated fat should be recommended to all diabetic patients to prevent cardiovascular disease. A balanced increase in consumption of fiber-rich foods and unsaturated fat is the most rational way to replace foods rich in saturated fat and cholesterol in the diabetic diet".

The collect information, dries peas with abundant water fibers may be considered as a functional food in reduced risk of hypercholesterolemia, one of major risk factor of cardiovascular disease.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Lipid Lowering with Soluble Dietary Fiber by Surampudi P1, Enkhmaa B1, Anuurad E1, Berglund L2,3.(PubMed)
(2) Soluble fiber intake at a dose approved by the US Food and Drug Administration for a claim of health benefits: serum lipid risk factors for cardiovascular disease assessed in a randomized controlled crossover trial by Jenkins DJ1, Kendall CW, Vuksan V, Vidgen E, Parker T, Faulkner D, Mehling CC, Garsetti M, Testolin G, Cunnane SC, Ryan MA, Corey PN.(PubMed)
(3) Effects of dietary fiber and carbohydrate on glucose and lipoprotein metabolism in diabetic patients by Riccardi G1, Rivellese AA.(PubMed)

Food Therapy: Coffee as Antioxidants

By Kyle J. Norton

Coffee may be used as functional food in improved antioxidant status in reduced risk of oxidative stress, irregular cells growth and reactive oxygen species causes of various types of disease, a joint study by renowned university study suggested.

Antioxidant is types of chemical compound inhibited the free radicals to protect the body against oxidative damage.
Coffee, a popular and social beverage all over the world, particular in the West, is a drink made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.

According to University of British Columbia, Coffee expressed numerous capacity in free radical scavenger in balancing hydrogen and electrons, acted as metal ion pro-oxidant chelators and triggered antioxidant gene expression and protected against gastrointestinal oxidative stress......

In vitro, according to cell-free and cell-based assays, coffee intake demonstrated antioxidant capacity through its bioactive constituents. And in cellular levels, coffee components exhibited antioxidant activity to specific genomic events through antioxidant function in both animal and human.

Furthermore, the Antioxidant Capacity of Coffee study suggested that coffee intake showed a potential effect in reduced free radical damage against artery-clogging atherosclerosis and health problems like vision loss, cancer or chronic diseases, through bioactive phytochemicals in expression of antioxidants.

Lower  antioxidant status also displayed a cellular damage especially in people with a low consumption of vegetables...and coffee.

Interestingly, in the evaluated polyphenol content and antioxidant capacity of widely consumed beverages such as chamomile tea, yerba mate, a coffee blend (65% roasted:35% green), and coffee-like substitutes, researchers at the Institute of Food Science found that coffee showed an average polyphenol recovery of 78%. after gastrointestinal digestion,  in vitro.

In compared to Yerba mate, coffee demonstrated a similar phenolic composition, but more stable polyphenols displayment..

Dr.Baeza G, the lead auhtor said, " Regular consumption of the studied beverages provides considerable amounts of antioxidants which are relatively stable after simulated digestion, and thus have the potential to prevent oxidative stress-related disorder".

The finding evidences suggested that coffee may be considered as a functional food in increased antioxidant profile, through bioactive constituents activities against diseases caused by over expression reactive oxygen species(RSO).

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Antioxidant property of coffee components: assessment of methods that define mechanisms of action by Liang N1, Kitts DD2.(PubMed)
(2) Investigating the Antioxidant Capacity of Coffee! by [No authors listed](PubMed)
(3) Polyphenol content, in vitro bioaccesibility and antioxidant capacity of widely consumed beverages by Baeza G1, Sarriá B1, Bravo L1, Mateos R1.(PubMed)

Food Therapy: Dried Peas Water Soluble Fibers in Reduced Risk of Cardiovascular Disease

Kyle J. Norton


Dried peas water soluble fibers may be used as functional food in reduced risk of cardiovascular disease, the recent study suggested.

According to the recommendation by FDA, consumption o fdietary fibers, beta-glucan (0.75 g/serving) and psyllium (1.78 g/serving) found in legume and other sources 4 servings/d may have a substantial effect in reduced cardiovascular disease risk.

Dried pea is a small but nutritionally mighty member of the legume family, genus Pisum belongings to the family Fabaceae with healthy source of proteins, fibers including beta-glucan and psyllium, vitamins and minerals.

In the study of 68 hyperlipidemic adults consumed a test (high-fiber) and a control low-fat (25% of energy), low-cholesterol (<150 mg/d) diet for 1 mo each in a randomized crossover study with high-fiber diet included 4 servings/d of foods containing beta-glucan or psyllium that delivered 8 g/d more soluble fiber than did similar with unsupplemented foods in the control diet, researchers after adjusting to other risk factors showed that risk of cardiovascular disease reduced significantly through lower all aspects of bad cholesterol and increased levels of HDL cholesterol.

Dr. Jenkins DJ, the led author said, "Although relatively small in terms of patient treatment, the reduction in cardiovascular disease risk is likely to be significant on a population basis".

Interestingly, in the review of Cochrane Central Register of Controlled Trials (CENTRAL) in The Cochrane Library, Ovid MEDLINE (1946 to January 2015), Ovid EMBASE (1947 to January 2015) and Science Citation Index Expanded (1970 to January 2015) as well as two clinical trial registers in January 2015, 23 RCTs (1513 participants randomised to examine the effect of dietary water fibre in cholesterol in induced CVD risk
1. There were no motility risk during the caused of study
2. Intake of water soluble fibers showed a significant effect on total cholesterol levels (17 trials (20 comparisons), and LDL cholesterol levels (mean difference -0.14 mmol/L, 95% CI -0.22 to -0.06)
3. Increased water fiber intake showed a small but statistically significant decrease rather than increase in HDL levels
4. There was insignificant effect on triglyceride levels
5 10 trials with 661 participants randomised reported a significant effect of increased fibre consumption on diastolic blood pressure but statistical significance in reduction of systolic blood pressure
6. Dietary water fibers injected demonstrated a mild to moderate gastrointestinal side-effects in compared to the control groups.

Dr. Hartley L, the led author after adjusting to other risk factors suggested. "The pooled analyses for CVD risk factors suggest reductions in total cholesterol and LDL cholesterol with increased fibre intake, and reductions in diastolic blood pressure" and "ll analyses need to be viewed with caution given the risks of bias observed for total cholesteroland the statistical heterogeneity observed for systolic blood pressure".

Taking altogether, there is no doubt that water soluble fibers found in dried peas and other sources may have a intrinsic effect in reduced risk cardiovascular disease in healthy and diabetics population through attenuating hypertension and hypercholesterolemia.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Soluble fiber intake at a dose approved by the US Food and Drug Administration for a claim of health benefits: serum lipid risk factors for cardiovascular disease assessed in a randomized controlled crossover trial by Jenkins DJ1, Kendall CW, Vuksan V, Vidgen E, Parker T, Faulkner D, Mehling CC, Garsetti M, Testolin G, Cunnane SC, Ryan MA, Corey PN.(PubMed)
(2) Dietary fibre for the primary prevention of cardiovascular disease by Hartley L1, May MD, Loveman E, Colquitt JL, Rees K.(PubMed)

Food Therapy: Maternal Coffee Caffeine intake in Risk of Infant Spina Bifida

By Kyle J. Norton


In compared to herbal medicine, food therapy even takes longer to ease symptoms, depending to stages of the treatment which directly address to the cause of disease.

Epidemiological studies do not agreed that coffee and coffee caffeine are associated to risk of birth defect of spina bifida.

Spina bifida is a congenitally physical abnormality characterized by incomplete closing of the backbone membranes around the spinal cord.

Coffee, second to green tea, is a popular and beverage all over the world, particular in the West,  made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.

According to the Slone Epidemiology Center at Boston University, in the study of caffeine consumption by women during the first month of pregnancy. Between 1988-2012, caffeine intake (<1, 1, and ≥2 cups/day) were not likely associated with increased risk of Spina bifida.

The researchers also suggested that other factors such as inadequate folic acid, recommended at 400 μg/day in the first month of pregnancy may also affect the outcome of the study assessed by the returned questionnaire of mothers with child Spina bifida.

Other, in the study of 133 case mothers and 273 control women providing information on periconceptional risk factors, using data from a case-control interview study carried out at the G. Gaslini Children's Hospital, Genoa, from 2000 to 2008, researchers found that there are numbers of mechanism involved in the expression of infant Spina bifida. High caffeine intake and lack of folate supplementation at any time of pregnancy may have some risks  in induced SB, but disturbed folate/homocysteine metabolism would be a main factor.

In animal studies, caffeine was considered as a reduced risk factor in exhibitedly significant effect in incidence of Spina bifida.

But in human observation study, caffeine consumption, during the year before pregnancy for 768 mothers of infants with NTDs and 4143 mothers of infants without birth defects between 1997 to 2002, was associated to increased risk of birth defect of SB.

Dr. Schmidt RJ, the lead author said, "Positive associations were observed between spina bifida and total caffeine consumption (OR 1.4; 95% CI: 1.1-1.9)" and "Additional studies should confirm whether women who consume caffeine are at increased risk for pregnancies complicated by NTDs".

The information findings suggested that caffeine intake may associate to some risks in the developed  fetus spina bifida, but the results were only come from observation studies, therefore, a human trial with large number size are necessary to clarify these contradictions.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half

Author biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Risk of spina bifida and maternal cigarette, alcohol, and coffee use during the first month of pregnancy by Benedum CM1, Yazdy MM, Mitchell AA, Werler MM.(PubMed)
(2) Maternal periconceptional factors affect the risk of spina bifida-affected pregnancies: an Italian case-control study by De Marco P1, Merello E, Calevo MG, Mascelli S, Pastorino D, Crocetti L, De Biasio P, Piatelli G, Cama A, Capra V.(PubMed)
(3) Maternal caffeine consumption and risk of neural tube defects by Schmidt RJ1, Romitti PA, Burns TL, Browne ML, Druschel CM, Olney RS; National Birth Defects Prevention Study.(PubMed)