Herbal Therapy: Chaste tree berry, a Functional Herb for Ameliorated Risk and Treatment of Gastric Cancer

Kyle J. Norton


The use of plants for healing purposes has been predated long before the existence of  modern medicine. Herbal plants have formed a fundamental source for conventional medicine in discovery of single ingredient medication, including aspirin (from willow bark), quinine (from cinchona bark), and morphine (from the opium poppy)......

The study conducted by respectable institution suggested that Chaste tree berry may have a potential effect in reduced risk and treatment of gastric/stomach cancer.

Gastric cancer is a condition of abnormal growth of the mucus-producing cells of the inside lining of the stomach. Adenocarcinoma is the most common type of gastric cancer.

Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of year as anaphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.

According to the Tokyo University of Pharmacy and Life Science, ethanol extract of the dried ripe fruit of Vitex agnus-castus (Vitex) displayed a strong cytotoxic activity against human gastric cancer cell through induction of apoptosis.

The efficacy of anti gastric cancer of the extract is a result of antioxidant activity in reduced progression of oxidative stress which can be detected through

using 2',7'-dichlorofluorescin-diacetate.

Dr.Ohyama K, the lead author said, " Our results demonstrate that intracellular oxidative stress and mitochondrial membrane damage is responsible for Vitex-induced apoptosis, which may be mediated by a diminution of reduced type glutathione within the cell".

Furthermore, in the support of the above differentiation, other study conducted by the same institution, suggested that Vitex extracted expressed the similar effect against human gastric signet ring carcinoma cell line, KATO-III, through separating or breaking of DNA in a time- and dose-dependent manner.

Additionally, the study also indicated,  Vitex-induced apoptosis by elevated the intracellular oxidative stress and mitochondrial membrane damage of gastric cancer cell lines through mediation of the presence of reduced type glutathione within the cell.

Other; in the investigate the cytotoxicity of the extract against serval human cancer cell line, including gastric signet ring carcinoma (KATO-III), colon carcinoma (COLO 201), showed that injection of the extract exhibited a significant effect in interference of the cell cycle division,reduced  DNA abnormal expression  through antioxidative reagent pyrrolidine dithiocarbamate or N-acetyl-L-cysteine (NAC).

Finally, according to Dr. Ohyama K, the lead author, the cytotoxic activity of Vitex extract may be attributed to the effect on cell growth in expression of apoptotic cell death by increased intracellular oxidation.

Taking together, chaste tree berry exerted anti cancer effect through various phytochemicals may be used as function food for ameliorated risk and treatment of gastric cancer, but intake of large amount should be taken with care.

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Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Human gastric signet ring carcinoma (KATO-III) cell apoptosis induced by Vitex agnus-castus fruit extract through intracellular oxidative stress by Ohyama K1, Akaike T, Imai M, Toyoda H, Hirobe C, Bessho T.(PubMed)
(2) Human gastric signet ring carcinoma (KATO-III) cell apoptosis induced by Vitex agnus-castus fruit extract through intracellular oxidative stress by Ohyama K1, Akaike T, Imai M, Toyoda H, Hirobe C, Bessho T.(PubMed)
(3) Cytotoxicity and apoptotic inducibility of Vitex agnus-castus fruit extract in cultured human normal and cancer cells and effect on growth by Ohyama K1, Akaike T, Hirobe C, Yamakawa T.(PubMed)

Herbal Therapy: Andrographis in Accelerated Wound Healing with Lesser Scar

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


The use of plants for healing purposes has been predated long before the existence of  modern medicine. Herbal plants have formed a fundamental source for conventional medicine in discovery of single ingredient medication, including aspirin (from willow bark), quinine (from cinchona bark), and morphine (from the opium poppy)......

Andrographis paniculata is also known as Andrographis, is a herbaceous plant, genus Andrographis, belonging to the family Acanthaceae, native to India and Sri Lanka, used in traditional Siddha and Ayurvedic in treating the common cold, flu, upper respiratory infections, infectious diseases, diarrhea, dysentery, cholera, pneumonia,.. .....

Wound healing is a natural response to restore injured tissues.

Andrographis paniculata leaf showed to process a significant wound healing effect in restoring injured tissues, a mentioned institute suggested.

According to the Universiti Teknologi MARA, topical application of Andrographis paniculata exerted a strong effect on the rate of wound enclosure with markedly less scar width and contained large amounts of fibroblast proliferation.

In a study of wound created in four groups of rat in posterior neck region. Blank placebo applied topically to the wounds of Group 1 and Groups 2 and 3 dressed with placebo containing 5% and 10% extracts of A. paniculata, groups treated with topical showed a rate of wound healing significantly accelerated in the wound dressed compared to placebo group.

The wound healing is also increased collagen and less formation of new blood vessels with absence of inflammatory cells.

Other study, in the evaluation of the effects of andrographis wound healing activity of Swiss Wistar strain rats with either sex with  topical application, 2%w/w ointment of ethanol extract and petroleum ether extract prepared in 2% w/w PEG-4000 in comparison to the left untreated control group, treatment groups showed a faster rate of complete healing in day 12 after topical application with wound contractions in petroleum ether extract, ethanolic extract were at 10.17 and 16.33, respectively.

Dr. Arnabaditya Mohanty, the lead authors in the joint study said, "Andrographis peniculata ethanolic extract possesses better wound healing property in comparison to control and also with petroleum ether extract".

Taking together, topical application of Andrographis paniculata leaf and extract may be used as a wound healing agent in accelerately restored injured tissues with lesser scar without induced adverse effects.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half  

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) Effect of Andrographis paniculata leaf extract on wound healing in rats by Al-Bayaty FH1, Abdulla MA, Abu Hassan MI, Ali HM.(PubMed) and(University of Malaya)
(2) Preliminary Pytochemical Screening and Wound Healing Activity of Andrographis Peniculata by Arnabaditya Mohanty1 , Dusmanta Kumar Pradhan1 , Manas Ranjan Mishra1 , Jitendra Kumar Sahoo1 , Ashutosh Mishra *2, Bankim Chan(Journal of Chemical and Pharmaceutical Research)

Herbal Therapy, Andrographis, The Anti Skin Cancer Whole Herb Medicine

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


The use of plants for healing purposes has been predated long before the existence of  modern medicine. Herbal plants have formed a fundamental source for conventional medicine in discovery of single ingredient medication, including aspirin (from willow bark), quinine (from cinchona bark), and morphine (from the opium poppy)......

Andrographis, the forgotten herbal medicine may consist a potency in reduced risk and treatment of skin cancer with fewer or no side effects, the renowned institute study suggested.

Andrographis paniculata is also known as Andrographis is a herbaceous plant, genus Andrographis, belonging to the family Acanthaceae, native to India and Sri Lanka. It has been used in traditional Siddha and Ayurvedic in treating the common cold, flu, upper respiratory infections, infectious diseases, diarrhea, dysentery, cholera, pneumonia,.....

Skin cancer is a medical condition of uncontrolled growth of abnormal skin cells and often detected at an early stage.


According to the joint study lead by the Sri Krishnadevaraya University, leaf extract of Andrographis nallamalayana (AN) significantly reduced the viability and survival of cells in skin cancer cell lines on A375 and B16F10 as shown in MTT assay and clonogenic assays.

The anti skin cancer effects of the leaf extract was also associated to ameliorate  the expression of Bcl-2, an anti-apoptotic protein in induced the expression of proapoptotic mechanism.

Dr. Purushotham G, the lead author said, "the extracts of AN exhibited significant anti-proliferative, anti-inflammatory and pro-apoptotic activities on melanoma skin cancer cell lines".

In immunofluorescence analysis, leaf extract Andrographis nallamalayana (AN), significantly attenuate the expression of NF-κB target genes with function in regulated cytoxocity expression in tumor cell.

Furthermore, the extract also exhibited the direct anticancer activity on cancer cells by cell-cycle arrest at G0/G1 phase through induction of cell-cycle inhibitory protein p27 involved cell proliferation and decreased expression of cyclin-dependent kinase 4 (CDK4) in cell controlling, probably through  enhancing immunomodulatory property.

Taking together, there is no doubt that Andrographis processes a pharmaceutical value in reduced risk and controlling skin cancer, but intake of large quantity can only be prescribed by herbalist.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half  

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) In vitro evaluation of anti-proliferative, anti-inflammatory and pro-apoptotic activities of the m ethanolic extracts of Andrographis nallamalayana Ellis on A375 and B16F10 melanoma cell lines by Purushotham G1,2, Padma Y1, Nabiha Y2, Venkata Raju RR3.(PubMed)
(2) Andrographolide, a potential cancer therapeutic agent isolated from Andrographispaniculata by Rajagopal S1, Kumar RA, Deevi DS, Satyanarayana C, Rajagopalan R.(PubMed)

Food Therapy: Coffee Caffeine in Increased Alertness and Rapid Reaction in Healthy Individuals

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


In compared to herbal medicine, food therapy even takes longer to ease symptoms, depending to stages of the treatment which directly address to the cause of disease.

Intake of coffee caffeine may have a potential effect in enhance alertness and rapid reaction, a renowned institute study suggested

Coffee, second to tea, is a popular and social beverage all over the world, particular in the West,  made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.

In a randomized, double-blind, parallel groups design to rate anxiety, alertness, and headache before and after 100 mg caffeine and again after another 150 mg caffeine given 90 min later, or after placebo on both occasions, researchers indicated that caffeine intake expressed a clean effect in elevated alertness in compared to placebo.

Further differentiation also found that caffeine did not increase alertness in low caffeine intake participants, and non caffeine administrated to medium and high intake groups displayed a reduced alertness effect and caffeine abstinence reduced alertness and consumption in compared to baseline.

Other, in the study of 30 healthy volunteers received equal volume drinks equivalent to either 1 or 2 cups of tea (containing 37.5 mg or 75 mg caffeine), or coffee (75 mg or 150 mg caffeine), or water, in a randomised five-way crossover design with drinks administered on four occasions during the day (0900, 1300, 1700 and 2300 hours), researchers found that there were no difference in all group in expression of alertness, but following the second beverage caffeinated coffee at 75 mg, there was a significantly improved reaction time (P<0.05), in compared to tea at the same dose and placebo.

Dr. Hindmarch I, the lead author said, " ingestion of caffeinated beverages may maintain aspects of cognitive and psychomotor performance throughout the day and evening when caffeinated beverages are administered repeatedly" and "This study also demonstrates that day-long tea consumption produces similar alerting effects to coffee, despite lower caffeine levels".

More importantly, in a total of 19 healthy volunteers ingested 400 ml black tea, coffee, caffeinated water, decaffeinated tea or plain water on three occasions through the day (0900, 1400 and 1900 hours), researchers filed the following reports
1. Caffeine ingestion was associated with a rapid (10 min) and persistent improvement of alertness and again independent of time of day, but did not acutely alter CFF threshold.
2. In compared to caffeine consumed group, water and decaffeinated group expressed steady decline in alertness (LARS) and cognitive capacity over the whole day.
3. Tea and coffee were similar on all measures, including alertness
4. Tea and coffee ingestion was associated with rapid increases in alertness and information processing capacity if tea was drinking throughout the day, in compared to other groups.

Taking altogether, there is no doubt that coffee intake have a enormous and profound effect in improved alertness and rapid reaction if drinking throughout the day, but reduced intake or adsence of coffee caffeine may cause the opposite effect.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half

Sources
(1) Association of the anxiogenic and alerting effects of caffeine with ADORA2A and ADORA1 polymorphisms and habitual level of caffeine consumption by Rogers PJ1, Hohoff C, Heatherley SV, Mullings EL, Maxfield PJ, Evershed RP, Deckert J, Nutt DJ.(PubMed)
(2) A naturalistic investigation of the effects of day-long consumption of tea, coffeeand water on alertness, sleep onset and sleep quality by Hindmarch I1, Rigney U, Stanley N, Quinlan P, Rycroft J, Lane J.(PubMed)
(2) The effects of black tea and other beverages on aspects of cognition and psychomotor performance by Hindmarch I1, Quinlan PT, Moore KL, Parkin C.(PubMed)

Food Therapy: Coffee Caffeine Protected Skin Aging by Increased Skin Blood Flow in Certain Areas in The Body

By Kyle J. Norton

In compared to herbal medicine, food therapy even takes longer to ease symptoms, depending to stage of the treatment which directly addresses to the cause of disease.

Epidemiological studies do not agreed that intake of coffee caffeine have a particular effect in skin blood flow, a joint respectable institutes study suggested.

Coffee, a popular and social beverage all over the world, particularly in the West, is a drink made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.

In the review of coffee caffeine effect in skin blood flow, researchers at the study lead by the Linköping University postulated that intake of caffeinated coffee exhibit a stronger expression in increased skin microvascular response to  transdermal iontophoresis of acetylcholine (ACh)( non‐invasively introduce vasoactive drugs in regulating the neurotransmitter at neuromuscular junctions), in compared to decaffeinated coffee intake group.

The study also found that coffee caffeine after intake displayed a significant effect in microvascular responses in the forearm skin and decreased blood flow in the finger tips, during the first hour after of drinking;

These result suggested that caffeine in coffee showed a enormous activity in increased blood flow in certain areas of the body's skin and decrease in others.

In a double-blind, placebo-controlled, crossover study performed in 27 healthy volunteers with oral intake of a cup either caffeinated or decaffeinated coffee and reactive hyperemia of finger blood flow assessed by laser Doppler flowmetry, within an interval of more than 2 days, the same experimental protocol was repeated with another coffee in a crossover manner, researchers showed that caffeinated coffee intake group demonstrated a slightly decreased finger blood flow in compared to decaffeinated coffee intake group.

According to the index of post-occlusive reactive hyperemia, microvascular endothelial function, in compared with decaffeinated coffee intake, caffeine contained showed a important effect in enhanced microvascular function in healthy individuals.

Taking together, the findings suggested that intake of coffee caffeine exerted a significant effect in promoted skin blood flow through microvascular function which may have strong impact in reduced skin ageing in some parts of the body.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Acute effects of coffee on skin blood flow and microvascular function by Tesselaar E1, Nezirevic Dernroth D2, Farnebo S3.(PubMed)
(2) Effect of caffeine contained in a cup of coffee on microvascular function in healthy subjects by Noguchi K1, Matsuzaki T2, Sakanashi M2, Hamadate N2, Uchida T2, Kina-Tanada M2, Kubota H2, Nakasone J2, Sakanashi M2, Ueda S3, Masuzaki H4, Ishiuchi S5, Ohya Y6, Tsutsui M7.(PubMed)

Herbal Therapy: Chaste Tree Berry, The Best Hepatoprotective Whole Herb Medicine

Kyle J. Norton


In herbal medicine, symptoms of the diseases can only be eased gradually, depending to stages of the treatment which directly address to the cause of the disease.

Chaste tree beery is found to associate with reduced risk of liver damage and diseases through various mechanisms, the recent study suggested

Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of year as anaphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.

In acetaminophen-induced hepatotoxicity in mice study, oral administration of chaste tree berry increased significantly in expression of levels of antioxidant in inhibition of free radicals domino' effect and levels of ferric ion in induced hepatotoxicity caused by acetaminophen.

According to the Al-Hikmah University, Hepatoprotective effects of chaste tree berry may also mediate the alternative effects of acetaminophen in serum alkaline phosphatase, alanine aminotransferase, aspartate aminotransferase, albumin and total bilirubin levels which can also contribute to hepatoxicity.

Dr. Ajiboye TO said, " Vitex doniana fruits possess antioxidant properties and halted acetaminophen-mediated oxidative rout on cellular proteins, lipids and DNA, made possible by β-sitosterol, platycodin D, apigenin, saikosaponin, chrysin and ellagitanin, (the antioxidants) in the extract".

Furthermore, ethanol extract Vitex glabrata (EEVG) on carbon tetrachloride-induced liver damage in rats, .displayed also antioxidant activity in inhibited superoxide dismutase, GSH, lipid peroxidation (LPO), catalase and peroxidase levels in liver homogenate.

Pre-treatment of the extract illustrated a strong inhibited effect against levels of LPO in CCl(4)-intoxicated livers and reduced the elevated serum levels of chemical compounds which can cause liver damage.

In fact, the extract display a enormous hepaprotective effect similar to those of silymarin through enhancing antioxidant mechanisms of its components, predominantly artemetin.

According to the The Vinayaka Mission’s College of Pharmacy study, in the CCl4 induced hepatic injury in albino rats, vitex extract not only is comparable to the standard drug, silymarin (100 mg/kg, p.o.), but also altered serum biomarker enzyme levels which were damage through injection of CCI4, to near normal in treated rats.

Taking together, there is no doubt that Chaste tree berry may process a protective effect in reduced risk of harmful chemicals and drugs induced liver damage, but injection of large amount should be taken with care.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half  

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Standardized extract of Vitex doniana Sweet stalls protein oxidation, lipid peroxidation and DNA fragmention in acetaminophen-induced hepatotoxicity by Ajiboye TO1.(PubMed)
(2) Antioxidant and hepatoprotective effects of ethanol extract of Vitex glabrata on carbon tetrachloride-induced liver damage in rats by Sridevi VK1, Chouhan HS, Singh NK, Singh SK.(PubMed)
(3) Effect of ethanol extract of flowers of Vitex trifolia Linn. on CCL4 induced hepatic injury in rats by Anandan R1, Jayakar B, Karar B, Babuji S, Manavalan R, Kumar RS.(PubMed)

Food Therapy: Black Bean, in Reduced Risk and Treatment of Colon Cancer

Kyle J. Norton

People who turn to alternative medicine for treatment of disease in avoidance of adverse effects induced by conventional medicine should be patient. In compared to herbal medicine; food therapy even takes longer than six months to ease symptoms, depending to stage of the treatment which directly address to the cause of disease.

Black or common bean with abundant fiber may be considered as function foods in reduced risk and treatment of colon cancer, a respectable institute suggested.

Colon cancer is a medical condition of the abnormal proliferation of cells in large intestine.

Black bean, a small roughly ovoid legume with glossy black shells, genus Phaseolus, belongings to the family Fabaceae can be bought in most grocery stores all around the year in dried and canned forms. It is believed that black bean was first domesticated growth in South America.

In a study of rats injected with azoxymethane (AOM)-induced colon cancer or saline and one week later administered an AIN, black bean (BB) and soy flour (SF)--based diet, researchers found that mice fed with black bean showed a significant expression in attenuated gene expression in coloncarcinogenesis by modulating cellular kinetics and reducing inflammation.

Others in the experiment to test the prevalence of high bean intake and low incidence of colon cancer in many Latin American countries in 53-wk-old weanling male F344 rats randomly assigned by weight to the following groups: control (11 rats), casein diet (21 rats), and bean diet (21 rats), with animals fed the casein and bean diets treated with the carcinogen azoxymethane (AOM) once weekly for 2 wk, the results returned showed a significantly fewer colon adenocarcinomas (P < 0.05) inrat fed with bean diet in compared control and rats fed the casein diet.

Rats fed with bean diet also expressed a lesser in tumor multiplication observed by tumors per tumor-bearing rat than in casein-fed rats.

Dt. Hughes JS, the lead researcher said, "dry beans contain anticarcinogenic compounds capable of inhibiting AOM-induced colon cancer in rats. However, the specific anticarcinogenic components within dry beans have not been identified".

But suggested that the efficacy of bean in reduced colon cancer risk may be results of the dietary fiber, phytochemicals or other components within dry beans,...

Promisingly, the results of rats fed a modified AIN-93G diet (control) or diets containing 75% black beans or 75% navy beans for 4 wk, and then colon cancer initiated by administration of two injections of azoxymethane 1 wk apart, also postulated a lower incidence  of colon cancer in rats fed the black bean (9%) in compared navy bean (14%) diets than in rats fed the control diet (36%) at 31 weeks.

In fact, rats fed the black bean also a significantly lower of total tumor multiplicity in compared to control.

Black bean consumption addressed a significant evidence that change of diet may exhibit  more controlled appetites, induced less body fat, and improved greater concentrations of butyrate in the distal colon, thus ameliorating prevalence of colon cancer

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Microarray Analyses of Genes Differentially Expressed by Diet (Black Beans and Soy Flour) during Azoxymethane-Induced Colon Carcinogenesis in Rats by Rondini EA1, Bennink MR.(PubMed)
(2) Dry beans inhibit azoxymethane-induced colon carcinogenesis in F344 rats by Hughes JS1, Ganthavorn C, Wilson-Sanders S.(PubMed)
(3) Consumption of black beans and navy beans (Phaseolus vulgaris) reduced azoxymethane-induced colon cancer in rats by Hangen L1, Bennink MR.(PubMed)