Holistic Health Articles and Research Related to Herbal Medicines, Foods and Phytochemicals

Wednesday, 19 July 2017

Food Therapy: Cruciferous Vegetables - The Whole Food Medicine in Expression of Immunodulatory Effects

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Whole food(herbal medicine) used as medical treatment, linking health benefits in prevention, management and treatment of diseases has induced much interests in today renowned scientists.
But many researchers have raised question of herbal quality, as geographic differences, time of grown and harvest, etc. may affect their's potency. I do believe, these questions can only be answered by experience herbalists.

Intake of cruciferous vegetables regularly may improve immune function in lowering the toxic effects of environmental pollutants such as dioxin.
Aryl hydrocarbon receptor (AhR), a protein best known for its role in mediating toxicity, showed to reduce toxin effect through exhibited intestinal immune function, according to the The University of Texas Southwestern Medical Center at Dallas.

Cruciferous vegetables are the group of vegetables belonging to the family Brassicaceae, including cauliflower, cabbage, cress, bok choy, broccoli etc.

Phenethyl isothiocyanate, a chemical found in Cruciferous Vegetables, in normal BALB/c mice study, promoted immune responses in inhibition of murine leukemia WEHI-3 cells, through stimulating the immunomodulations.

Other phytochemicals, indole-3-carbinol and sulforaphane (SFN), found in the vegetables also addressed the immunodulatory effects against suppression of growth of murine WEHI-3 leukemia cells through immune promotion of increased the level of T cells and decreased the level of macrophages, a mobile white blood cell in responsible for detecting, engulfing and destroying pathogens and apoptotic cells.

In enzyme-linked immunosorbent assay, sulforaphane (SFN), inhibited T cell proliferation and the production of inflammatory cytokins in rheumatoid arthritis (RA) by enhancing the antiarthritic and immune regulatory effects.

Truly, Cruciferous Vegetable has no doubt processed immunodulatory effects through the presence of its phytochemicals in promotion of immune function.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) You AhR what you eat: linking diet and immunity by Hooper LV1.(PubMed)
(2) Phenethyl isothiocyanate promotes immune responses in normal BALB/c mice, inhibits murine leukemia WEHI-3 cells, and stimulates immunomodulations in vivo by Tsou MF1, Tien N, Lu CC, Chiang JH, Yang JS, Lin JP, Fan MJ, Lu JJ, Yeh SP, Chung JG.(PubMed)
(3) In vitro suppression of growth of murine WEHI-3 leukemia cells and in vivo promotion of phagocytosis in a leukemia mice model by indole-3-carbinol by Lu HF1, Tung WL, Yang JS, Huang FM, Lee CS, Huang YP, Liao WY, Chen YL, Chung JG.(PubMed)
(4) Inhibition of synovial hyperplasia, rheumatoid T cell activation, and experimental arthritis in mice by sulforaphane, a naturally occurring isothiocyanate by Kong JS1, Yoo SA, Kim HS, Kim HA, Yea K, Ryu SH, Chung YJ, Cho CS, Kim WU.(PubMed)

Herbal Therapy: Aloe Vera, the Natural Whole Food Medicine for Reduced Aging Wrinkle

Aloe Vera or Aloe Vera supplement may be used to delay skin aging degeneration in induced expression of wrinkle.

Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan. It is very popular for commercial cultivation due to its health benefits, used in herbal medicine in treating many kinds of disease, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated of cholesterol, etc.

Wrinkle is a skin degenerative condition caused by the loss of dermis and subcutaneous fat layer underneath the skin, leading to a slight line or fold on the skin, particular in the face.

According to the Food Ingredients & Technology Institute, daily oral intake of plant sterols of Aloe vera gel (Aloe sterol) significantly increases the skin barrier function, moisture, and elasticity in photoprotected skin of that may reduce risk of skin wrinkle.

In a 12-week, randomized, double-blind, placebo-controlled study, in 48 apparently healthy men (age range: 30-59 years; average: 45 years), intake of oral Aloe sterol supplementation after 12 weeks showed a significant improvement of the skin elasticity index in comparison in the baseline value.

Dr. Tanaka M, the lead author said, "Aloe sterol ingestion increased skin elasticity in the photodamaged skin of men aged <46 years, and "No Aloe sterol intake-dependent harmful phenomenon was observed during the intake period".

Furthermore, in vitro, Aloe sterols increased production of collagen and hyaluronic acid, natural substance in skin response to connective, epithelial, and neural tissues. approximately two-fold and 1.5-fold, and promoted gene expression levels in human dermal fibroblasts.

In fact, daily oral Aloe sterol-containing Aloe vera gel powder (AVGP) significantly reduced facial wrinkles in women aged ≥40 years as well as stimulated collagen and hyaluronic acid production by human dermal fibroblasts.

In support of the above evaluation, intake of Aloe Vera gel enhanced healthy skin through promoting elasticity (R2), net elasticity (R5), and biological elasticity (R7) scores and skin fatigue area F3,the Food Ingredients and Technology Institute 12 weeks study suggested.

Taking altogether, there is no doubt that oral administration of Aloe Vera or Aloe Vera supplements may improve skin condition caused by skin aging degeneration, but quality of amount intake should only be prescribed by related field specialist.

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) Effects of plant sterols derived from Aloe vera gel on human dermal fibroblasts in vitro and on skin condition in Japanese women by Tanaka M1, Misawa E1, Yamauchi K1, Abe F1, Ishizaki C2.(PubMed)
(2) Effects of Aloe Sterol Supplementation on Skin Elasticity, Hydration, and Collagen Score: A 12-Week Double-Blind, Randomized, Controlled Trial by Tanaka M1, Yamamoto Y, Misawa E, Nabeshima K, Saito M, Yamauchi K, Abe F, Furukawa F.(PubMed)
(3) Aloe sterol supplementation improves skin elasticity in Japanese men with sunlight-exposed skin: a 12-week double-blind, randomized controlled trial by Tanaka M1, Yamamoto Y2, Misawa E1, Nabeshima K1, Saito M1, Yamauchi K1, Abe F1, Furukawa F2.(PubMed)

Tuesday, 18 July 2017

Food Therapy: Asparagus, the Natural Whole Food for Reduced Risk, Complications and Treatment of Oral Cancer

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Whole food(herbal medicine) used as medical treatment, linking health benefits in prevention, management and treatment of diseases has induced much interests in today renowned scientists.
But many researchers have raised question of herbal quality, because geographic differences, time of grown and harvest, etc. may effect their's potency. I do believe, these questions can only be answered by experience herbalists.

Regular intake of Asparagus may have a reduced risk of progression and development of oral cancer, the renowned institution study suggested.

Treatment of oral cancer in conventional medicine involved immune suppression through the need of antibiotics may contribute to complications of patients with oral cancer, such as infection prompt many patients to research for alternative treatment with little or no side effects.

According to University of Florida, supplement, such as asparagus use currently in cancer prevention rather than treatment.of oral cancer probably due to mechanism of action for bioactive compounds, such as epigallocatechin, epicatechin-3-gallate,....

Dr. the lead author said, " Preclinical and clinical evidence for the use of green tea, raspberry, asparagus, and cannabis extracts is discussed in this review. Diet changes, supplementation with antioxidants, high-dose vitamin C therapy, and cannabinoid use have been suggested to decrease cancer cell replication and increase chance of remission"

Asparagus is a flowering plant belong to species the genus Asparagus, native to the western coasts of northern Spain, north to Ireland, Great Britain, and northwest Germany, northern Africa and western Asia, used from early times as a vegetable and medicine, because of its delicate flavour and diuretic properties.

Oral cancer is any malignant cell growth in the tissue located in the oral cavity, including the tissue of the lips or the tongue, cheek lining, floor of the mouth, gums (gingiva) and the roof of the mouth (palate).

In the study of blood sample of 40 oral cancer patients undergoing treatment in the radiotherapy unit of Regional Cancer Institute, Asparagus racemosus Willd. exerted a strong effect against infection caused byStaphylococcus aureus (23.2%), Escherichia coli (15.62%), Staphylococcus epidermidis (12.5%), Pseudomonas aeruginosa (9.37%), Klebsiella pneumonia (7.81%), Proteus mirabilis (3.6%), Proteus vulgaris (4.2%) and the fungal pathogens Candida albicans (14.6%), Aspergillus fumigatus (9.37%).

Researchers at the institute also suggested, oral cancer patients were neutropenic with abnormally low level of neutrophils and and prone to secondary micro infection.. Asparagus may be used as antimicrobial agent to check the secondary infections in cancer patients.

Taking altogether, asparagus has shown to exert a significant anti progression, complications and treatment of oral cancer, but further multi centers and large sample size studies are necessary to validate this claim.

Herbal Therapy: Cayenne, the Natural Whole Food Medicine for Gastrointestinal protective effects

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Whole food(herbal medicine) used as medical treatment, linking health benefits in prevention, management and treatment of diseases has induced much interests in today renowned scientists.
Many researchers have raised a question of their's effectiveness as quality of the herbs may be affected by geographic differences, time of grown and harvest, etc. I do believe that these questions can only be answered by experience herbalist.

Cayenne, the chili spice have been used in traditional medicne for treatment of Gastrointestinal disorder. According to recent study, cayenne exerted various beneficial effects on the gastrointestinal system by variety of mechanisms such as influence of gastric emptying, stimulation of gastrointestinal defense and absorption, stimulation of salivary, intestinal, hepatic, and pancreatic secretions.

Cayenne is also known as Cayenne Pepper, a red, hot chili pepper, belonging to Capsicum annuum, the family Solanaceae, native to sub-tropical and tropical regions, used in traditional medicine to increases metabolism, enhance circulatory system and stomach and the intestinal tract, adjust blood pressure, lower LDL cholesterol and triglycerides, treat frostbite, muscles, arthritis, rheumatism, low back pain, strains, sprains, bruises and neuralgia, etc.

According to the Royal Adelaide Hospital, in evaluation of eight healthy volunteers, intake of cayenne showed to slower the rate of gastric emptying and faster the whole gut transit after the meal compared with the other meal.

In fact, adding chilli in the meal is associated with a faster whole gut transit time, affecting the intestinal transit or gastric emptying.

In an 18 well nourished healthy human adult volunteers study, Dr. Kochhar KP, the lead researchers at the All India Institute of Medical Sciences, said, " The t1/2 of the spicy meal, 40.09 +/- (p < 0.05) thus implying a faster transit through the stomach" and " In 17 out of the 18 subjects, t1/2 of the spicy meal was consistently lower than that of spice free meal".

Intake of Cayenne regularly no doubt have improved the gastrointestinal function through increased metabolism. use of chili supplement should be taken with care to prevent toxicity

Herbal Therapy: Alfalfa, the Immunomodulatory Natural Whole Food Medicine

The use of plants for healing purposes have been predated long before the existence of modern medicine. Herbal plants have formed a fundamental sources for conventional medicine in discovery of single ingredient medication, including aspirin (from willow bark), quinine (from cinchona bark), and morphine (from the opium poppy)......

Alfalfa is a flowering plant in the genus Medicago, belonging to the family Fabaceae, The plants have been cultivated all over the world as hay for cattle feeding, and used in traditional medicine over thousands of year to treat high cholesterol, asthma, osteoarthritis, rheumatoid arthritis, diabetes, enhance digestive system, bleeding disorder, kidney and urinary tract infection, etc. North Americal aboriginal has used Alfalfa seed as food, such as making bread and mush.

Immunomodulatory effect is function of immune system involved many reactions, including antimicrobial organism against infection and inflammation, modulated genes expression.......This modulation may also induced by neurohormonal system.

Alfalfa may be a potential herbal medicine used for enhanced immune system for fighting against forming of free radicals and invasion of foreign substance through its immunomodulatory effects.

Polysavone, a natural extract from alfalfa, induced the proliferation of T and B white blood cells, lymphocytes and improved antibody against viral invasion significantly in comparison to the control group, according to the animal study.

Dr. Xiaofang Dong at the Qiqihar University said, " Polysavone may decrease abdominal fat deposition and enhance immunity without an adverse effect on the performance of broiler chickens"

In a total of A total of 360 1-d-old male commercial Arbor Acre broiler chickens, dietary polysavone (Alfalfa extract) in comparison to chlortetracycline supplementation, polysavone group showed a excellent scavenging activity in inhibited free radical expression, particular for 1,1-diphenyl-2-picrylhydrazyl and superoxide anion radicals, through it The imunomodulatory effects in improved immune function in compared chlortetracycline supplementation group.

Furthermore, alfalfa flavonoids extract (AFE) also promoted immune function in regulating the population of microbe, enhancing antioxidant properties by increasing antioxidase activity and affecting immunity by changing the proportion of white blood cell and Innate immunity.

Taking altogether, alfalfa may be effective in promoted immune system fighting against forming of free radical and microbial infection, but human trials are necessary to confirm this validation.

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) Effect of Polysavone (Alfalfa Extract) on Abdominal Fat Deposition and Immunity in Broiler Chickens(Researchgate)
(2) Effects of dietary polysavone (Alfalfa extract) and chlortetracycline supplementation on antioxidation and meat quality in broiler chickens by Dong XF1, Gao WW, Su JL, Tong JM, Zhang Q.(PubMed)
(3) Effects of alfalfa flavonoids on the production performance, immune system, and ruminal fermentation of dairy cows by Zhan J1, Wu C1, Liu M1, Su X1, Zhan K1, Zhang C1, Zhao G1.(PubMed)

Monday, 17 July 2017

Food Therapy: Broccoli Sprout, the Best Natural Whole Food for Treatment of Asthma

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The use of plants for healing purposes have been predated long before the existence of modern medicine. Herbal plants have formed a fundamental sources for conventional medicine in discovery of single ingredient medication, including aspirin (from willow bark), quinine (from cinchona bark), and morphine (from the opium poppy)......

Sulforaphane, the main chemical constituent of broccoli Sprout may activate anti inflammatory activity in open upper airway for reduced risk of asthma and asthma complications.

Asthma is a chronic inflammatory disease affecting the air way of the lung with recurring symptoms, such as wheezing, chest tightness, shortness of breath, and coughing. The disease affects people of all ages, and mostly starts during childhood.

Cruciferous vegetables are the group of vegetables belonging to the family Brassicaceae, including cauliflower, cabbage, cress, bok choy, broccoli, etc.

According to the study from the UCLA team, in a total 65 participated volunteers, 3 days of oral administration of broccoli or preparations sprout of 100 grams significant increased antioxidant enzymes in compared with the placebo group.

At a maximum doses of 200 grams, broccoli sprout induced significant increase of detoxified(GSTP1) and antibody NQO1, enzymes.

In support of the above, the phase II antioxidant enzymes in the human upper airway insisred, broccoli sprout demonstrated the potential antioxidant effect to reduce the inflammation of oxidative stress in induction of airway disease, such as asthma.

A randomized controlled trial in healthy young adults, also suggested that chemical compound isothiocyanates found in cruciferous vegetable, including broccoli sprout, exhibited anti inflammatory effects through altered serum concentrations of interleukin (IL)-6, IL-8, C-reactive protein (CRP), in increased the presence of inflammation in the body tumor, and necrosis factor (TNF) α,, involved in systemic inflammation.

Intake of cruciferous Vegetables(broccoli sprouts) have shown to reduce the circulation of proinflammatory cytokins, namely IL-6 through inhibited the expression of abnormal function of gene Glutathione S-Transferase Theta 1(GSTT1) metabolism in lower the levels of glutathione, the anioxidant with anti inflammatory properties.

Dr. Navarro SL, the lead researchers said, " IL-6 concentrations were significantly lower on day 14 of (the double-dose cruciferous) (2xC) and (cruciferous plus apiaceous (carrot family) 1xC+A diets than with the basal diet,...respectively" and " Twenty-four-hour urinary isothiocyanate excretion was not associated with any of the inflammation markers overall; however, IL-6 was inversely associated with total isothiocyanate excretion in GSTM1(The antioxidant enzyme)".

Taking altogether, intake of broccoli sprout regularly is associated to lower the effect of proinflammatory cytokins and increase detoxified and enzymes in ameliorated airway inflammation in patient with asthma.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) Broccoli may help protect against respiratory conditions like asthma by Rachel Champeau | March 02, 2009
(2) Cruciferous vegetables have variable effects on biomarkers of systemic inflammation in a randomized controlled trial in healthy young adults by Navarro SL1, Schwarz Y2, Song X2, Wang CY2, Chen C2, Trudo SP3, Kristal AR2, Kratz M2, Eaton DL4, Lampe JW2.(PubMed)
(3) Oral sulforaphane increases Phase II antioxidant enzymes in the human upper airway by Riedl MA1, Saxon A, Diaz-Sanchez D.(PubMed)

Food Therapy: Cruciferous Vegetables, the Best Natural Whole Food Medicine for Reduced risk and Treatment of Chronic Diseases

Cruciferous vegetables are the group of vegetables belonging to the family Brassicaceae, including cauliflower, cabbage, cress, bok choy, broccoli etc.

Intake of cruciferous vegetables regularly may reduce risk and improve treatment of multiple chronic diseases.

Chronic diseases are medical conditions, lasting more than three months.

Recent study conducted by the joint study lead by the Suzhou Science and Technology Town Hospital, suggested that sulforaphane (SFN), a derivative of glucoraphanin presented in cruciferous vegetables, exhibited a strongly therapeutic effects on inflammation-related diseases in induction of chronic pain in animals with chronic constriction injury.

Dr. Wang C and Dr. Wang C, suggested that Sulforaphane (SFN) reduced inflammation induced pain may be a result of its attenuation of behavioral hypersensitivity without affecting SFN modulation of inflammatory cytokines.

Addition to that, fhe chemical compound also found to enhance the production of Nrf2, a master regulator of detoxification and also antioxidant, anti-inflammatory and other cytoprotective mechanisms, in prevented and/or treated a large number of chronic inflammatory diseases, including various cardiovascular diseases, kidney diseases, lung diseases, diseases of toxic liver damage.

Dr. Houghton CA, the lead author of the study said, " By virtue of its lipophilic nature and low molecular weight, sulforaphane displays significantly higher bioavailability than the polyphenol-based dietary supplements that also activate Nrf2. Nrf2 activation induces cytoprotective genes such as those playing key roles in cellular defense mechanisms including redox status and detoxification"

Indole-3-carbinol (I3C), other common phytochemical found in cruciferous vegetables, may be a another potential agent in prevention of chronic diseases, through its effect in biological activities on cellular and molecular levels, according to joint study lead by the Poznan University of Medical Sciences.

Taking together, there is no doubt that intake of cruciferous Vegetables regularly have a potential property in reduced risk and treatment of multiple chronic illness, because of its effects in improved functions of over 500 genes in cellular defense mechanisms including redox status and detoxification and anti inflammatory in induction of chronic diseases.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sourcesd
(1) Anti-nociceptive and anti-inflammatory actions of sulforaphane in chronic constriction injury-induced neuropathic pain mice by Wang C1, Wang C2.(PubMed)
(2) Indole-3-Carbinol and Its Role in Chronic Diseases by Licznerska B1, Baer-Dubowska W2.(PubMed)
(3) Nrf2, a master regulator of detoxification and also antioxidant, anti-inflammatory and other cytoprotective mechanisms, is raised by health promoting factors by Pall ML1, Levine S2.(PubMed)
(4) Sulforaphane and Other Nutrigenomic Nrf2 Activators: Can the Clinician's Expectation Be Matched by the Reality? by Christine A. Houghton, Robert G. Fassett, and Jeff S. Coombes(PubMed)