The holistic Prevention, Management and Treatment of Dementia - Common antioxidants (scavengers) Bilirubin

Kyle J. Norton (Scholar) 
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                                 Dementia

Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.
                           

           Common antioxidants (scavengers) Bilirubin

The expression of added to a mixture in order to remove or de-activate impurities and unwanted oxygen in the cellular level for reduced risk of oxidative stress defence in plants and animals.

1. Bilirubin
Bilirubin is a prosthetic group with a unique function in breaking down molecules into smaller units for releasing energy, excreted in bile and urine(263). As a cellular antioxidant, it protected against diseases associated with oxidative stress, through mildly elevated serum bilirubin levels and activation of heme oxygenase(264) and reverted to biliverdin, a green tetrapyrrolic bile pigment, through antioxidant redox cycle in inhibition of the effects of mutagens when oxidized(265). A significant reduction of levels ofbilirubin, has shown to associate to patients with Alzheimer's disease(AD)(266).


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The Best Way to prevent, treat your disease, including dementia 
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Pregnancy Miracle
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Using Holistic Ancient Chinese Medicine

References
(263) New insights in bilirubin metabolism and their clinical implications b Sticova E1, Jirsa M.(PubMed)
(264) Bilirubin chemistry and metabolism; harmful and protective aspects by Vítek L1, Ostrow JD.(PubMed)
(265) Direct Antioxidant Properties of Bilirubin and Biliverdin. Is there a Role for Biliverdin Reductase? by Jansen T1, Daiber A.(PubMed)
(266) Decreased plasma antioxidants in patients with Alzheimer's disease. by Kim TS1, Pae CU, Yoon SJ, Jang WY, Lee NJ, Kim JJ, Lee SJ, Lee C, Paik IH, Lee CU.(PubMed)

The holistic Prevention, Management and Treatment of Dementia - The Antioxidant Metals binding proteins Myoglobin

Kyle J. Norton (Scholar) 
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                                 Dementia

Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.

         The Antioxidant Metals binding proteins Myoglobin

The expression of metal-binding proteins or peptides in microorganisms and plants in order to enhance heavy metal accumulation and/or tolerance has great potential, according to Dr. Malin Mejárea, Leif Bülow in the study of Metal-binding proteins and peptides in bioremediation and phytoremediation of heavy metals, leading to reduced oxidative stress defense in plants

7. Myoglobin
Myoglobin is an iron- and oxygen-binding protein found in the muscle tissue of vertebrates. The binding of oxygen by myoglobin(260) through interaction with pathogens establishment of successful infection and survival is probably through peroxidase activity(261) in reducing the free radicals damage caused by oxidate stress(261)(262).

8. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including dementia 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How ToPermanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

References
(260) Spiking in cytosolic calcium concentration in single fibrinogen-bound fura-2-loaded human platelets by Heemskerk JW1, Hoyland J, Mason WT, Sage SO.(PubMed)
(261) Molecular characterization of Clonorchis sinensis secretory myoglobin: delineating its role in anti-oxidative survival. by Ren M, He L, Huang Y, Mao Q, Li S, Qu H, Bian M, Liang P, Chen X, Ling J, Chen T, Liang C, Wang X, Li X1, Yu X.(PubMed)
(262) Molecular characterization of Clonorchis sinensis secretory myoglobin: delineating its role in anti-oxidative survival by Ren M, He L, Huang Y, Mao Q, Li S, Qu H, Bian M, Liang P, Chen X, Ling J, Chen T, Liang C, Wang X, Li X1, Yu X.(PubMed)

The holistic Prevention, Management and Treatment of Dementia - The Antioxidant Metals binding proteins Hemoglobin

Kyle J. Norton (Scholar) 
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                                 Dementia

Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.

             The Antioxidant Metals binding proteins Hemoglobin

The expression of metal-binding proteins or peptides in microorganisms and plants in order to enhance heavy metal accumulation and/or tolerance has great potential, according to Dr. Malin Mejárea, Leif Bülow in the study of Metal-binding proteins and peptides in bioremediation and phytoremediation of heavy metals, leading to reduced oxidative stress defense in plants

6. Hemoglobin
Hemoglobin, the protein molecule in red blood cells enhances the carrying of oxygen from the lungs to the body's tissues and return CO2 from the tissues to the lungs(255)(256). During oxidate stress, the cell membrane is protected by intraerythrocytic hemoglobin from the forming of free radicals(259), probably through regulating NO(258) and auxin homeostasis(257).


Chinese Food Therapy
The Best Way to prevent, treat your disease, including dementia 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How ToPermanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

References
(255) Blood substitutes: evolution from noncarrying to oxygen- and gas-carrying fluids by Cabrales P1, Intaglietta M.(PubMed)
(256) Hemoglobin solutions and tissue oxygenation by Muir WW1, Wellman ML.(PubMed)
(257) Plant hemoglobin participation in cell fate determination by Huang S1, Hill RD1, Stasolla C1.(PubMed)
(258) The dual effects of nitrite on hemoglobin-dependent redox reactions. by Lu N1, Chen C2, He Y3, Tian R4, Xiao Q5, Peng YY6.(PubMed)
(259) Redox reactivity in propolis: direct detection of free radicals in basic medium and interaction with hemoglobin by Mot AC1, Damian G, Sarbu C, Silaghi-Dumitrescu R.(PubMed)

The holistic Prevention, Management and Treatment of Dementia - The Antioxidant Metals binding proteins Transferrin

Kyle J. Norton (Scholar) 
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                                 Dementia

Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.

           The Antioxidant Metals binding proteins Transferrin


The expression of metal-binding proteins or peptides in microorganisms and plants in order to enhance heavy metal accumulation and/or tolerance has great potential, according to Dr. Malin Mejárea, Leif Bülow in the study of Metal-binding proteins and peptides in bioremediation and phytoremediation of heavy metals, leading to reduced oxidative stress defense in plants

5. Transferrin
Transferrin, a glycoprotein binded iron very tightly but reversibly, enhances the immune system in fighting against infection, inflammation(250) by creating an environment low in free iron(251) impeded to cell oxidation(253)(254), through rapidly evolving sites reverse to bacterial binding in counteract bacterial iron piracy(250). Transferrin deformation and aggregation are found to associate to neurological disorders such as Parkinson's and Alzheimer's disease(252).



Chinese Food Therapy
The Best Way to prevent, treat your disease, including dementia 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How ToPermanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

References
(250) Nutritional immunity. Escape from bacterial iron piracy through rapid evolution of transferrin by Barber MF1, Elde NC2.(PubMed)
(251) Total iron binding capacity and transferrin concentration in the assessment of iron status by Kasvosve I1, Delanghe J.(PubMed)
(252) Fibrillation of transferrin by Booyjzsen C1, Scarff CA, Moreton B, Portman I, Scrivens JH, Costantini G, Sadler PJ.(PubMed)
(253) The formation of Fe3+-transferrin-CO3(2-) via the binding and oxidation of Fe2+ by Kojima N, Bates GW.(PubMed)
(254) Iron released from transferrin at acidic pH can catalyse the oxidation of low density lipoprotein. by Lamb DJ1, Leake DS.(PubMed)

The holistic Prevention, Management and Treatment of Dementia - The Antioxidant Metals binding proteins Metallothionein

Kyle J. Norton (Scholar) 
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                                 Dementia

Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.

      The Antioxidant Metals binding proteins Metallothionein


The expression of metal-binding proteins or peptides in microorganisms and plants in order to enhance heavy metal accumulation and/or tolerance has great potential, according to Dr. Malin Mejárea, Leif Bülow in the study of Metal-binding proteins and peptides in bioremediation and phytoremediation of heavy metals, leading to reduced oxidative stress defence in plants

4. Metallothionein
Metallothionein, a family of cysteine-rich(244), low molecular weight proteins binds both physiological heavy metals(245) through detoxified fraction of accumulation(245) by capturing harmful superoxide and hydroxyl radicals(246) through binding the metal ions(247)(248) bounded to cysteine(249).


Chinese Food Therapy
The Best Way to prevent, treat your disease, including dementia 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How ToPermanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

References
(244)Lactoferrin in infant formulas: effect on oxidation by Satué-Gracia MT1, Frankel EN, Rangavajhyala N, German JB.(PubMed)
(245) Contrasting metal detoxification in polychaetes, bivalves and fish from a contaminated bay.by Fan W1, Xu Z2, Wang WX3.(PubMed)
(246) Channa punctata brain metallothionein is a potent scavenger of superoxide radicals and prevents hydroxyl radical-induced in vitro DNA damage by Atif F1, Kaur M, Ansari RA, Raisuddin S.(PubMed)
(247) In vitro free radical scavenging activity of hepatic metallothionein induced in an Indian freshwater fish, Channa punctata Bloch by Atif F1, Kaur M, Yousuf S, Raisuddin S.(PubMed)
(248) Possible role of cutaneous metallothionein in protection against photo-oxidative stress--epidermal localization and scavenging activity for superoxide and hydroxyl radicals by Hanada K1, Baba T, Hashimoto I, Fukui R, Watanabe S.(PubMed)
(249) Quantitation of human metallothionein isoforms: a family of small, highly conserved, cysteine-rich proteins by Mehus AA1, Muhonen WW, Garrett SH, Somji S, Sens DA, Shabb JB.(PubMed)

The holistic Prevention, Management and Treatment of Dementia -The Antioxidant Metals binding proteins Lactoferrin

Kyle J. Norton (Scholar) 
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                                 Dementia

Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.

The Antioxidant Metals binding proteins Lactoferrin


The expression of metal-binding proteins or peptides in microorganisms and plants in order to enhance heavy metal accumulation and/or tolerance has great potential, according to Dr. Malin Mejárea, Leif Bülow in the study of Metal-binding proteins and peptides in bioremediation and phytoremediation of heavy metals, leading to reduced oxidative stress defence in plants

 3. Lactoferrin
Lactoferrin, a multifunctional protein of the transferrin family, is one of the components of the immune system(240) of the body used for fighting against foreign invasion of bacteria and virus(241)(242) and lipid oxidation(243) by inhibiting oxidation in a concentration-dependent manner even at concentrations beyond its capacity(244).


Chinese Food Therapy
The Best Way to prevent, treat your disease, including dementia 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How ToPermanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

References
(240) Antiviral properties of lactoferrin--a natural immunity molecule. by Berlutti F1, Pantanella F, Natalizi T, Frioni A, Paesano R, Polimeni A, Valenti P.(PubMed)
(241) Potential lactoferrin activity against pathogenic viruses. by Redwan EM1, Uversky VN2, El-Fakharany EM3, Al-Mehdar H4.(PubMed)
(242) The antimicrobial activity of lactoferrin: current status and perspectives. by Orsi N1.(PubMed)
(243) Role of lipid oxidation, chelating agents, and antioxidants in metallic flavor development in the oral cavity by Omür-Özbek P1, Dietrich AM, Duncan SE, Lee Y.(PubMed)
(244)Lactoferrin in infant formulas: effect on oxidation by Satué-Gracia MT1, Frankel EN, Rangavajhyala N, German JB.(PubMed)

The holistic Prevention, Management and Treatment of Dementia - The Antioxidant Metals binding proteins Ceruloplasmin

Kyle J. Norton (Scholar) 
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                                 Dementia

Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.

                           The Antioxidant Metals binding proteins Ceruloplasmin


The expression of metal-binding proteins or peptides in microorganisms and plants in order to enhance heavy metal accumulation and/or tolerance has great potential, according to Dr. Malin Mejárea, Leif Bülow in the study of Metal-binding proteins and peptides in bioremediation and phytoremediation of heavy metals, leading to reduced oxidative stress defence in plants.


2. Ferritin
Ferritin, the protein produced by almost all living organisms, acts as a component to fight against iron deficiency and iron overload(233)(234). In a soluble and non-toxic form, the protein is transported to the body needs, including organs(236) for enhancement of the immune system in the presence of an infection(237), against proliferation of lymphoid and myeloid cells(235), cancer(238) and prevention of the infectious agent in attempt of binding iron to form free radicals(239) in most cellular oxidation reactions(239).


Chinese Food Therapy
The Best Way to prevent, treat your disease, including dementia 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How ToPermanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

References
(233) Sulforaphane reduces the alterations induced by quinolinic acid: modulation of glutathione levels. by Santana-Martínez RA1, Galván-Arzáte S2, Hernández-Pando R3, Chánez-Cárdenas ME1, Avila-Chávez E4, López-Acosta G1, Pedraza-Chaverrí J5,Santamaría A6, Maldonado PD7.(PubMed)
(234) Ferritin in the red cells of normal subjects and patients with iron deficiency and iron overload. by Cazzola M, Arosio P, Barosi G, Bergamaschi G, Dezza L, Ascari E.(PubMed)
(235) New functions for an iron storage protein: the role of ferritin in immunity and autoimmunity. by Recalcati S1, Invernizzi P, Arosio P, Cairo G.(PubMed)
(236) CoCl2-induced biochemical hypoxia down regulates activities and expression of super oxide dismutase and catalase in cerebral cortex of mice. by Rani A1, Prasad S.(PubMed)
(237) Transferrin and ferritin response to bacterial infection: the role of the liver and brain in fish. by Neves JV1, Wilson JM, Rodrigues PN.(PubMed)
(238) The significance of ferritin in cancer: anti-oxidation, inflammation and tumorigenesis. by Alkhateeb AA1, Connor JR.(PubMed)
(239) The iron-binding protein Dps2 confers peroxide stress resistance on Bacillus anthracis. by Tu WY1, Pohl S, Gizynski K, Harwood CR.(PubMed)