The holistic Prevention, Management and Treatment of Dementia - Deficiency Causes of dementia Due to Aging

Kyle J. Norton (Scholar) 
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                                 Dementia

Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.

         Deficiency Causes of dementia Due to Aging

1. Vitamin D and 1,25-dihydroxyvitamin D(3) deficiency
Vitamin D levels not only plays an important role in the pathogenesis of many age-associated diseases including cancer, heart disease, type 2 diabetes
mellitus and stroke, but also associate with increased risk of prevalent cognitive dysfunction. According to number of studies, raising vitamin D plays a role in decreased cognitive dysfunction and dementia(24). Evidence from epidemiological also insisted the association between 25(OH)D concentrations and systolic blood pressure, risk for CV disease-related deaths, symptoms of depression, cognitive deficits, and mortality(25).

2. Folic acid with vitamin B12 deficiency
Folates are vitamins essential to the development of the central nervous system. Deficiency of folate can increase the risk of dementia. According to Cochrane Dementia and Cognitive Improvement Group, folic acid plus vitamin B12 were effctive in reducing the serum homocysteine concentrations, with no adverse effects(26).

3. Vitamin B12 deficiency
An association between neuropsychiatric disorders and vitamin B12deficiency has been recognized since 1849. Deficiency of Vitamin B12 are found in many elders and might contribute to age-associated cognitive impairment, according to the Scientist at Cochrane Dementia and Cognitive Improvement Group(27).

4. Vitamin B6 deficiency
Vitamin B6 supplementation showed to reduce the risk of developing cognitive impairment in older healthy people, and improve cognitive functioning of people with cognitive decline and dementia, according the study conducted by Cochrane Dementia and Cognitive Improvement Group(28).

5. Deficiency of Insulin-like growth factor (IGF)-1and growth hormones
Deficiency of Insulin-like growth factor (IGF)--1 hormone may contribute to the genesis of cognitive impairment and dementia in the elderly patients. Old age, in the absence of circulating IGF-1, a hormone with a complex role in brain function has seen to link to an acceleration of neurological diseases(29) Growth hormone and IGF-1 replacement showed to increase neurogenesis, vascular density, and glucose utilization, and alter NMDA receptor subunit composition in brain areas implicated learning and memory, in animal (30)and children(31) studies.

8. Deficiency of cerebrospinal fluid melatonin
Melatonin plays an essential role in ventricular system via choroid plexus portals. In Alzheimer's disease, inadequate melatonin increases risk of the neuropathological changes due to hydroxyl radicals cause of damage mitochondria and initiated cascade of oxygen radicals(32).

9. Decreased dehydroepiandrosterone (DHEA)
Dehydroepiandrosterone sulfate (DHEAS) concentrations
DHEA, a neurosteroid secreted by the adrenal cortex. is also a neurosteroid. The levels of dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) concentrationsare decline in concentration with age(33).

10. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How ToPermanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References(24) Vitamin D, cognitive dysfunction and dementia in older adults by Dickens AP1, Lang IA, Langa KM, Kos K, Llewellyn DJ.(PubMed)
(25) Extraskeletal effects of vitamin D in older adults: cardiovascular disease, mortality, mood, and cognition by Barnard K1, Colón-Emeric C.(PubMed)
(26) Folic acid with or without vitamin B12 for cognition and dementia by Malouf M1, Grimley EJ, Areosa SA.(PubMed)
(27) Vitamin B12 for cognition by Malouf R1, Areosa Sastre A.(PubMed)
(28) The effect of vitamin B6 on cognition by Malouf R1, Grimley Evans J.(PubMed)
(29) Aging, synaptic dysfunction, and insulin-like growth factor (IGF)-1 by Deak F1, Sonntag WE.(PubMed)
(30) Growth hormone and insulin-like growth factor-1 (IGF-1) and their influence on cognitive aging by Sonntag WE1, Ramsey M, Carter CS.(PubMed)
(31) The role of the somatotropic system in cognition and other cerebral functions by Creyghton WM1, van Dam PS, Koppeschaar HP.(PubMed)
(32) Alzheimer's disease: roles for mitochondrial damage, the hydroxyl radical, and cerebrospinal fluid deficiency of melatonin by Maurizi CP1.(PubMed)
(33) Decreased dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS)

The holistic Prevention, Management and Treatment of Dementia - Free radical causes of dementia

Kyle J. Norton (Scholar) 
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                                 Dementia

Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.

                           
           Free radical causes of dementia

B.1. Alzheimer’s disease
1. Free radical and Alzheimer’s disease
Free radicals causes of Alzheimer’s disease is well defined in many researches(34). Oxidative stress-induced injury involved the selective modification of different intracellular proteins may lead to the neurofibrillary degeneration of neurons in the brain(34a)(34b).

2. Antioxidants and Alzheimer’s disease
a. Docosahexaenoic acid (DHA)
Change of brain aging in DHA metabolism, was found in patients with Alzheimer's disease(34c)(34d). DHA, a naturally occurring component found in every cell membrane with ability to increase phosphatidylserine(35)(35a) is important in decreased production of proinflammatory omega-6 eicosanoids causes of Alzheimer's disease(35b) and in improved the memory of animals with Alzheimer's disease by suppressing oxidative damage in the brain(41).

b. Vitamin E
Vitamin E reduced generalized inflammation, may slow the decline of mental and physical abilities in people with Alzheimer's disease (AD) over the long term(36). Also vitamin E inhibited cells damage and cells death caused by beta-amyloid(36a)(36b), which is toxic to brain cells(36c).

c. Phosphatidylserine
Patients who had Alzheimer’s disease taken100 milligrams per day (mg/day) of phosphatidylserine scored significantly better on standardized memory tests at the end of the 12-week trial period than patients without(37)(40).

d. Antioxidants
Antioxidant are found at much lower levels for patients with Alzheimer’s disease(38), such as serum of vitamin A, C, E, zinc and transfferin. Carotenoids are fat-soluble antioxidants that may protect polyunsaturated fatty acids, such as n-3 fatty acids from oxidation(39)

e. Muscarinic cholinergic receptors
Alzheimer’s disease patients showed to exhibit the significant loss of muscarinic cholinergic receptors neurons(42) causes of reduced volume of neural transmission that can lead to loss of memory(43).

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How ToPermanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer


References
(34) Possible causes of Alzheimer's disease: amyloid fragments, free radicals, and calcium homeostasis by Hölscher C1.(PubMed)
(34a) PROTEIN OXIDATION IN THE BRAIN IN ALZHEIMER'S DISEASE M. Y. AKSENOV,a,d* M. V. AKSENOVA,a,b D. A. BUTTERFIELD,a,c J. W. GEDDESa,d and W. R. MARKESBERYa,b a Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, US.(Pergamon)
(34b) Interactions between β-amyloid and central cholinergic neurons: implications for Alzheimer's disease by Satyabrata Kar, Stephen P.M. Slowikowski, David Westaway, and Howard T.J. Mount(PubMed)
(34c) The Impact of Cholesterol, DHA, and Sphingolipids on Alzheimer's Disease by Marcus O. W. Grimm, Valeri e C. Zimmer, 1 Johannes Lehmann, Heike S. Grimm, and Tobias Hartmann (PubMed)
(34d) DHA Improves Cognition and Prevents Dysfunction of Entorhinal Cortex Neurons in 3xTg-AD Mice Dany Arsenault,1,2 Carl Julien,1,2 Cyntia Tremblay,2 and Frédéric Calon1,2,(PubMed)
(35) Administration of DHA-PS to aged mice was suitable for increasing hippocampal PS and DHA ratio by Ohkubo T1, Tanaka Y.(PubMed)
(35a) Neuronal specific increase of phosphatidylserine by docosahexaenoic acid.by Guo M1, Stockert L, Akbar M, Kim HY.(PubMed)
(35b) Docosahexaenoic acid (DHA), an essential fatty acid for the proper functioning of neuronal cells: their role in mood disorders By Alfonso Valenzuela B. ( University of Chile)
(36) Vitamin E for Alzheimer's dementia and mild cognitive impairment by Farina N1, Isaac MG, Clark AR, Rusted J, Tabet N.(PubMed)
(36a)Inflammatory mediator and beta-amyloid (25-35)-induced ceramide generation and iNOS expression are inhibited by vitamin E by Ayasolla K1, Khan M, Singh AK, Singh I.(PubMed)
(36b) Vitamin E but not 17beta-estradiol protects against vascular toxicity induced by beta-amyloid wild type and the Dutch amyloid variant by Muñoz FJ1, Opazo C, Gil-Gómez G, Tapia G, Fernández V, Valverde MA, Inestrosa NC.(PubMed)
(36c) Parkin protects against mitochondrial toxins and beta-amyloid accumulation in skeletal muscle cells by Rosen KM1, Veereshwarayya V, Moussa CE, Fu Q, Goldberg MS, Schlossmacher MG, Shen J, Querfurth HW.(PubMed)
(37) Soybean-Derived Phosphatidylserine Improves Memory Function of the Elderly Japanese Subjects with Memory Complaints by Akito Kato-Kataoka,1,* Masashi Sakai,1 Rika Ebina,1 Chiaki Nonaka,2 Tsuguyoshi Asano,3 and Takashi Miyamori4(PubMed)
(38) Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease by Mota SI1, Costa RO1, Ferreira IL1, Santana I2, Caldeira GL3, Padovano C3, Fonseca AC3, Baldeiras I4, Cunha C5, Letra L5, Oliveira CR4, Pereira CM6, Rego AC7.(PubMed)
(39) Nutritional biomarkers in Alzheimer's disease: the association between carotenoids, n-3 fatty acids, and dementia severity by Wang W1, Shinto L, Connor WE, Quinn JF.(PubMed)
(40) The effect of soybean-derived phosphatidylserine on cognitive performance in elderly with subjective memory complaints: a pilot study by Yael Richter, Yael Herzog, Yael Lifshitz, Rami Hayun, and Sigalit Zchut(PubMed)
(41) Action of long-chain fatty acids on protein kinase C activity: comparison of omega-6 and omega-3 fatty acids.by Holian O1, Nelson R.(PubMed)
(42) Interactions between β-amyloid and central cholinergic neurons: implications for Alzheimer's disease by Satyabrata Kar, Stephen P.M. Slowikowski, David Westaway, and Howard T.J. Mount(PubMed)
(43) Chapter 12Memory Impairments Associated with Stress and Aging by Carmen Sandi.(PubMed)

The holistic Prevention, Management and Treatment of Dementia - Types of dementia

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                                 Dementia

Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.

                           Types of dementia

1. Alzheimer's disease

Alzheimer's disease is a brain disorder named for German physician Alois Alzheimer(1). Alzheimer's destroys brain cells, causing problems with memory, thinking and behavior severe enough to affect language communication, memory, lifelong hobbies or social life. Alzheimer's gets worse over time, and it is fatal(2). Over 1 million people in US alone are currently afflicted by Alzheimer's disease because of degeneration of hippocampus and cerebral cortex(3) of the brain where memory, language and cognition(4) are located. With this mental disorder, brain cells gradually die and generate fewer and fewer chemical signals day by day resulting in diminished of functions. Overtime memory thinking as well as behavior deteriorates. Today, there is no known cure.

2. Absence of acetylcholine
If the nerves located in front of the brain perish(5), caused by diminished quality of acetylcholine due long term alcohol abused may result of cognitive dysfunction(6) causes of language difficulty, memory loss, concentration problem, and anxiety- and depression-like behaviors(8),reduced moblile skills because of lacking reaction in muscular activity and refection(7).

3. Dementia due to long-term alcohol abuse
Dementia is common in patients with alcoholism(9). Most classic is the Korsakoff's dementia resulted in extremely poor short term memory(10) and often associated with the memory losses of confabulations due to diminished processing resources and/or an encoding or retrieval deficit(11).

4. Multi-infarct dementia
Also known as vascular dementia, is the second most common form of dementia after Alzheimer's disease in older adults caused by different mechanisms all results in vascular lesions(12) of the brain(13).

5. Dementia associated with Parkinson's disease
Parkinson disease (PD) is a disabling, progressive condition, causes of cognitive deficits due to the interruption of frontal-subcortical loops that facilitate cognition and parallel the motor loop(15)(16) due to loss of substantia nigra pars compacta (SNc) dopamine (DA) neurons(14).

6. Creutzfeldt-Jakob disease (CJD)
People who have eaten contaminated beef(18) for many years may be infected without even knowing it. Creutzfeldt-Jakob disease is a quickly progressing and fatal disease consisted of dementia(19), muscle abnormal functions(17).

7. Subdural hematoma
It is the accumulation of blood beneath the outer cover of the brain resulted from the rupture of blood vessel(20)(21). Subdural hemorrhages may increase intracranial pressure(22), causing compression and damage to delicate brain tissue. Acute subdural hematoma has a high mortality rate(23).

Other types of dementia include metabolic disorders, dementia due to long-term substance abuse, hypothyroidism, and hyperethyroidism.


References
(1) Alzheimer's disease (Wikipedia)
(2) Understanding dementia in the sociocultural context: a review by Cipriani G1, Borin G2.(PubMed)
(3) What is normal in normal aging? Effects of aging, amyloid and Alzheimer's disease on the cerebral cortex and the hippocampus by Fjell AM1, McEvoy L2, Holland D3, Dale AM4, Walhovd KB5; Alzheimer's Disease Neuroimaging Initiative.(PubMed)
(4) Does degree of gyrification underlie the phenotypic and genetic associations between cortical surface area and cognitive ability? by Docherty AR1, Hagler DJ Jr2, Panizzon MS3, Neale MC4, Eyler LT5, Fennema-Notestine C6, Franz CE3, Jak A7, Lyons MJ8, Rinker DA9, Thompson WK10, Tsuang MT11, Dale AM12, Kremen WS13.(PubMed)
(5) Acetylcholine facilitates recovery of episodic memory after brain damage by Croxson PL1, Browning PG, Gaffan D, Baxter MG.(PubMed)
(6) Postsynaptic activity reverses the sign of the acetylcholine-induced long-term plasticity of GABAA inhibition by Domínguez S1, Fernández de Sevilla D2, Buño W3.(PubMed)
(7) Induction of dystrophin-associated proteins together with nicotinic acetylcholine receptors by denervation in the absence of dystrophin in skeletal muscles of mdx mice by Mitsui T1, Kawai H, Kawajiri M, Kunishige M, Aki K, Saito S.(PubMed)
(8) Mice lacking the β4 subunit of the nicotinic acetylcholine receptor show memory deficits, altered anxiety- and depression-like behavior, and diminished nicotine-induced analgesia by Semenova S1, Contet C, Roberts AJ, Markou A.(PubMed)
(9) Magnetic resonance imaging in alcoholic Korsakoff's syndrome: evidence for an association with alcoholic dementia by Emsley R1, Smith R, Roberts M, Kapnias S, Pieters H, Maritz S.(PubMed)
(10) Rates of forgetting in Alzheimer-type dementia and Korsakoff's syndrome by Kopelman MD.(PubMed)
(11) Non-verbal, short-term forgetting in the alcoholic Korsakoff syndrome and Alzheimer-type dementia by Kopelman MD1.(PubMed)
(12) Vascular dementia: different forms of vessel disorders contribute to the development of dementia in the elderly brain by Thal DR1, Grinberg LT, Attems J.(PubMed)
(13) Pathology and pathogenesis of vascular cognitive impairment-a critical update by Jellinger KA1.(PubMed)
(14) What causes the death of dopaminergic neurons in Parkinson's disease? by Surmeier DJ1, Guzman JN, Sanchez-Padilla J, Goldberg JA.(PubMed)
(15) Frontal-subcortical circuitry and behavior Circuitos fronto-subcorticales y conducta Circuits fronto-sous-corticaux et comportement, Raphael M. Bonelli, MD; DMedSc*
Raphael M. Bonelli, Department of Psychiatry, Graz Medical University, Graz, Austria ;
Jeffrey L. Cummings, MD,
Jeffrey L. Cummings, Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, Calif, USA;(PubMed)
(16) The Frontal Lobes and Neuropsychiatric Illness, edited by Stephen P. Salloway, Paul F. Malloy, James D. Duffy
(17) [A case of Creutzfeldt-Jakob disease presenting with arm levitation as an initial symptom].
[Article in Japanese] by Kamogawa K1, Ninomiya S, Okuda S, Matsumoto Y, Tomita H, Okamoto K, Okuda B.(PubMed)
(18) Bovine spongiform encephalopathy and variant Creutzfeldt-Jakob disease: how safe is eating beef? by Roma AA1, Prayson RA.(PubMed)
(19) Immune responses in rapidly progressive dementia: a comparative study of neuroinflammatory markers in Creutzfeldt-Jakob disease, Alzheimer's disease and multiple sclerosis by Stoeck K, Schmitz M, Ebert E, Schmidt C, Zerr I.(PubMed)
(20) Acute subdural hematoma from bridging vein rupture: a potential mechanism for growth by
Miller JD1, Nader R.(PubMed)
(21) Association of subdural hematoma with increased mortality in lobar intracerebral hemorrhage by
Patel PV1, FitzMaurice E, Nandigam RN, Auluck P, Viswanathan A, Goldstein JN, Rosand J, Greenberg SM, Smith EE.(PubMed)
(22) Acute spontaneous subdural hematoma: an unusual form of cerebrovacular accident by Naama O1, Belhachmi A, Ziadi T, Boulahroud O, Abad Elasri C, Elmostarchid B, Boucetta M.(PubMed)
(23) Fatal deterioration of delayed acute subdural hematoma after mild traumatic brain injury: two cases with brief review by Chen S1, Xu C, Yuan L, Tian H, Cao H, Guo Y.(PubMed)

Antioxidants: The Summary

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Human aging is a biological process, no one can stop, but delay it. It is possible that one person has a physiological younger than his or her biological if one engages in healthy living life style and eating healthily by increasing the intake of good healthy food such as whole grain, fruits, vegetables, beans and legumes, etc. and reducing the consumption of harmful foods, such as saturated fat, trans fat, artificial ingredients, etc.
                      

              

                                         The Summary



Aging is a natural process, no one can stop but delay it. Over last 20+ years, researchers found that free radicals have played a majors role in the progression of aging process as they damage every cells of the whole body. One of the majoy cause of free radical is that of setting a chain reaction, if left unchecked, it can cause death of the cells, triggering the attack to the adjacent cells. At the middle age, due to weakened immune system, damage of body organs and reduced levels of antioxidants, our health is deteriorate and aging progressed at a fast rate, it is up to you to delay it by eating healthy, living a healthy style, exercise, etc. if you want to look younger than you biological age, live longer, healthier and diseases free.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity

and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How ToPermanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Antioxidants: The immune system - The Effects of antioxidants on immune system

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Human aging is a biological process, no one can stop, but delay it. It is possible that one person has a physiological younger than his or her biological if one engages in healthy living life style and eating healthily by increasing the intake of good healthy food such as whole grain, fruits, vegetables, beans and legumes, etc. and reducing the consumption of harmful foods, such as saturated fat, trans fat, artificial ingredients, etc.
                      

              

                                         The immune system

An immune system is a system of biological structures and processes within an organism that protects against disease by identifying and killing pathogens, including bacteria, virus, parasites, etc. and tumor cells, including irregular cells growth, cancer cells to keep us healthy. In most cases, the immune system does a great job of keeping people healthy and preventing infections. But sometimes problems with the immune system can lead to illness and infection.

    The Effects of antioxidants on immune system

Enzyme antioxidants, superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase are best known to defense our body in fighting or scavenging against forming of free radicals by neutralizing them. Other antioxidants include
a. Zinc
Zinc, as a antioxidant is essential mineral in ading immune system by enhancing the peoper function of T cells which belong to a group of white blood cells known as lymphocytes, in fighting against damaging free radicals.

b. Selenium
Selenium is one of the powerful antioxidant. In the extracellular space, it helps to influence immune processes by proliferating the response to mitogen, and macrophages, leukotriene.

c. Vitamin A
vitamin A plays an essential roles in enhancing a broad range of immune processes, including lymphocyte activation and proliferation, T-helper-cell differentiation, the production of specific antibody isotypes and regulation of the immune response.

d. Vitamin C
Researchers found that vitamin C raised the concentration in the blood of immunoglobulin A, M that promotes the ability of antibodies and phagocytic cells to clear pathogens.

e. Vitamin E
In aged mice study showed that Vitamin E beside increased both cell-dividing and IL-producing capacities of naive T cells it also enhances the immune functions in association with significant improvement in resistance to influenza infection.

f. Carotenoids
Carotenoids reduces oxidation damage to cells and protects LDL cholesterol from oxidation, thus reducing the risk of aging and chronic diseases caused by damaging free radicals.

g. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity

and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How ToPermanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Antioxidants: The immune system - How free radicals affect Immune system

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Human aging is a biological process, no one can stop, but delay it. It is possible that one person has a physiological younger than his or her biological if one engages in healthy living life style and eating healthily by increasing the intake of good healthy food such as whole grain, fruits, vegetables, beans and legumes, etc. and reducing the consumption of harmful foods, such as saturated fat, trans fat, artificial ingredients, etc.
                      

              

                                         The immune system

An immune system is a system of biological structures and processes within an organism that protects against disease by identifying and killing pathogens, including bacteria, virus, parasites, etc. and tumor cells, including irregular cells growth, cancer cells to keep us healthy. In most cases, the immune system does a great job of keeping people healthy and preventing infections. But sometimes problems with the immune system can lead to illness and infection.


            How free radicals affect Immune system

There are many factors which affect immune system as we age. Hormone declining such as human growth hormone and Dehydroepiandrosterone (DHEA) are the major influences. In factor, some researchers suggested free radicals is one of major contribution to the declining of immune system.
a. Thymus
The declining of the thymus function contributes a direct effect on the immune system due to diminish of quantity of T cells and immune factors.

b. Lipid peroxidation
Researchers found that lipid peroxidation are able to attack immune cells membrane, leading to the impediment of cells membrane activities, causing susceptibility diseases found in aging person.

c. NADHP oxidase
NADHP oxidase (nicotinamide adenine dinucleotide phosphate-oxidase) is a membrane-bound enzyme complex found in the plasma membrane. Free radicals cause damage to membrane, leading to diminish of its function in fighting against foreign invasion.

d. Cytokine
Free radicals damage immune cells that affect the function of cytokines in transmitting intercellular signals, leading to many disease states and conditions ranging from major depression and Alzheimer's disease to cancer.

e. Etc.
 

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity

and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How ToPermanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Antioxidants: The immune system - Types of free radicals utilized by Immune system

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Human aging is a biological process, no one can stop, but delay it. It is possible that one person has a physiological younger than his or her biological if one engages in healthy living life style and eating healthily by increasing the intake of good healthy food such as whole grain, fruits, vegetables, beans and legumes, etc. and reducing the consumption of harmful foods, such as saturated fat, trans fat, artificial ingredients, etc.
                      

              

                                         The immune system

An immune system is a system of biological structures and processes within an organism that protects against disease by identifying and killing pathogens, including bacteria, virus, parasites, etc. and tumor cells, including irregular cells growth, cancer cells to keep us healthy. In most cases, the immune system does a great job of keeping people healthy and preventing infections. But sometimes problems with the immune system can lead to illness and infection.

Types of free radicals utilized by Immune system

Free Radicals play an important role in the function of the Immune System. The immune systen produce free radicals to kill foreign microbes, but the production of free radical sometime can be excessive, leading to formation of a large number of free radicals that stimulate the formation of more free radicals, leading to even more damage, until they are brought to stop.


a. Nitric oxideNitric oxide is also generated by phagocytes of immune system as part of the human immune response. It is produced as free radicals and toxic to bacteria, that helps the immune system in regulating the armamentarium of phagocytes that play a role in inflammation.
Nitric oxide can contribute to reperfusion injury if excessive amount produced during reperfusion and reacts with superoxide to produce the damaging oxidant peroxynitrite.

b. Superoxide
Superoxide is a compound that possesses the superoxide anion with the chemical formula O2−. It is biologically quite toxic and is deployed by the immune system to kill invading microorganisms produced in large quantities by the enzyme NADPH oxidase.
If over produce, superoxide may contribute to the pathogenesis of many diseases , such as radiation poisoning and hyperoxic injury and aging as aresult of oxidation.

c. Neutrophils
Neutrophils, the phagocytes can internalize and kill microbes, but each phagocytic event causes the formation of a phagosome into which reactive oxygen species (ROS) and hydrolytic enzymes are secreted, leading to respiratory burst, resulting in activating the enzyme NADPH oxidase, which produces large quantities of superoxide.

d. Chain reaction
Since free radicals are caused by the body’s own natural processes by stealing oxygen electron from other cell, its chain effect result in production of even more free radicals. These aditional free radicals continue until they are stopped, leading to toxins, radiation, etc. that weakens the immune system.

e. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity

and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How ToPermanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer