Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Fibromyalgia Alternative Treatment - S-adenosylmethionine

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                                      Fibromyalgia

Fibromyalgia, according to the American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia in the newly proposed criteria for the classification of fibromyalgia are 1) widespread pain in combination with 2) tenderness at 11 or more of the 18 specific tender point sites(a) as a result in responding to pressure.

                        The Treatment

B. Alternative treatments 
Several types of alternative medicine have some potential for future clinical research. However, due to methodological inconsistencies across studies and the small body of evidence, no firm conclusions can be made at this time. we present here some of alternatives which have played an important role in human history for treatment of Fibromyalgia, according to the DePaul University(231) and Dicle University(232), in review of information regarding the efficacy of complementary and alternative medicine (CAM).

4. S-adenosylmethionine 
S-adenosylmethionine, found in almost every tissue and fluid in the body, plays an essential role involved many processes of the body, including the immune system, cell membranes, etc.....
S-adenosylmethionine may be used for treatment of symptoms of pain in patient with fibromyalgia.

Dr. De Silva V and colleagues at theUniversity of Aberdeen, said, "...., S-adenosylmethionine each showed at least one statistically significant improved outcome compared with placebo" in the study of the management of fibromyalgia(242).

Dr. Fetrow CW Dr. Avila JR insited, despite of several reviews and at least two meta-analyses agreed with efficacy as available evidence surrounding SAMe in the therapy of depression as SAMe was superior to placebo in treating depressive disorders in comparison to standard tricyclic antidepressant,as the risk profile of the supplement has not been assessed(243).

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The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet


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Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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References

(242) Evidence for the efficacy of complementary and alternative medicines in the management of fibromyalgia: a systematic review by De Silva V1, El-Metwally A, Ernst E, Lewith G, Macfarlane GJ; Arthritis Research Campaign working group on complementary and alternative medicines.(PubMed)

(243) Efficacy of the dietary supplement S-adenosyl-L-methionine by Fetrow CW1, Avila JR.(PubMed)

Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Fibromyalgia Alternative treatments - L-carnitine

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                                      Fibromyalgia

Fibromyalgia, according to the American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia in the newly proposed criteria for the classification of fibromyalgia are 1) widespread pain in combination with 2) tenderness at 11 or more of the 18 specific tender point sites(a) as a result in responding to pressure.

                        The Treatment

B. Alternative treatments 
Several types of alternative medicine have some potential for future clinical research. However, due to methodological inconsistencies across studies and the small body of evidence, no firm conclusions can be made at this time. we present here some of alternatives which have played an important role in human history for treatment of Fibromyalgia, according to the DePaul University(231) and Dicle University(232), in review of information regarding the efficacy of complementary and alternative medicine (CAM).
3. L-carnitine
Involved in lipid metabolism, L-carnitine may be used for treatment as an althernative medicne for treatment of Fibromyalgia's symptoms. According to the, Acetyl-L-carnitine, a synthic form of L-carnitine attenuated depressive symptoms, pain, and improved the quality of life of FMS patients in comparison with the efficacy of duloxetine(240).
In a double-blind, multicenter trial comparing acetyl l-carnitine with placebo in the treatment of fibromyalgia involved 102 patients, indicate that LAC may be of benefit in patients with FMS, as it induced statistically significant in ameliorated depression and musculo-skeletal pain(241).

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity 
and restore your health naturally with Chinese diet

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Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References

(240) A randomised controlled trial comparing duloxetine and acetyl L-carnitine in fibromyalgic patients: preliminary data by Leombruni P1, Miniotti M1, Colonna F1, Sica C1, Castelli L2, Bruzzone M3, Parisi S3, Fusaro E3, Sarzi-Puttini P4, Atzeni F5, Torta RG1.(PubMed)

(241) Double-blind, multicenter trial comparing acetyl l-carnitine with placebo in the treatment of fibromyalgia patients by Rossini M1, Di Munno O, Valentini G, Bianchi G, Biasi G, Cacace E, Malesci D, La Montagna G, Viapiana O, Adami S.(PubMed)

Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Fibromyalgia Alternative Treatment - The Magnesium therapy

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                                      Fibromyalgia

Fibromyalgia, according to the American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia in the newly proposed criteria for the classification of fibromyalgia are 1) widespread pain in combination with 2) tenderness at 11 or more of the 18 specific tender point sites(a) as a result in responding to pressure.

                        The Treatment

B. Alternative treatments 
Several types of alternative medicine have some potential for future clinical research. However, due to methodological inconsistencies across studies and the small body of evidence, no firm conclusions can be made at this time. we present here some of alternatives which have played an important role in human history for treatment of Fibromyalgia, according to the DePaul University(231) and Dicle University(232), in review of information regarding the efficacy of complementary and alternative medicine (CAM).
2. Magnesium therapy
Magnesium therapy or Transdermal magnesium therapy is one of easy, convenient, and affordable form of alternative medicine used of topical or oral administration magnesium for treatment of Fibromyalgia. According to the Centre Hospitalier de Toulon, slight lower levels of magnesium is found in patients with Fibromyalgia(237).

In a study of 60 premenopausal women diagnosed with fibromyalgia according to the ACR criteria and 20 healthy women, also suggested that low magnesium levels in the erythrocyte might be an etiologic factor on fibromyalgia symptoms, as the combined amitriptyline + magnesium citrate treatment significantly improved over all parameters except numbness(238).

But in the study of the relationship between serum antioxidant vitamins, magnesium levels, and clinical parameters in patients with primary fibromyalgia syndrome, Dr. Sakarya ST and researchers at the Ondokuz Mayis University said, " ....other complex mechanism may play an important role in the pathophysiology of FM" other than plasma antioxidant vitamins and Mg levels(239).

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References

(235) Acupuncture for fibromyalgia in primary care: a randomised controlled trial by Vas J1, Santos-Rey K2, Navarro-Pablo R3, Modesto M2, Aguilar I2, Campos MÁ4, Aguilar-Velasco JF5, Romero M4, Párraga P5, Hervás V3, Santamaría O3,Márquez-Zurita C2, Rivas-Ruiz F6.(PubMed)

(236) Acupuncture and Trigger Point Injections for Fibromyalgia: East-West Medicine Case Report by Taw LB, Henry E.(PubMed)

(237) Selenium and magnesium status in fibromyalgia by Eisinger J1, Plantamura A, Marie PA, Ayavou T.(PubMed)

(238) Is magnesium citrate treatment effective on pain, clinical parameters and functional status in patients withfibromyalgia? by Bagis S1, Karabiber M, As I, Tamer L, Erdogan C, Atalay A.(PubMed)

(239) The relationship between serum antioxidant vitamins, magnesium levels, and clinical parameters in patients with primary fibromyalgia syndrome by Sakarya ST1, Akyol Y, Bedir A, Canturk F.(PubMed)

Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Fibromyalgia Alternative Treatment - The Acupuncture

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                                      Fibromyalgia

Fibromyalgia, according to the American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia in the newly proposed criteria for the classification of fibromyalgia are 1) widespread pain in combination with 2) tenderness at 11 or more of the 18 specific tender point sites(a) as a result in responding to pressure.

                        The Treatment

B. Alternative treatments 
Several types of alternative medicine have some potential for future clinical research. However, due to methodological inconsistencies across studies and the small body of evidence, no firm conclusions can be made at this time. we present here some of alternatives which have played an important role in human history for treatment of Fibromyalgia, according to the DePaul University(231) and Dicle University(232), in review of information regarding the efficacy of complementary and alternative medicine (CAM).
1. Acupuncture
Altering gaining Acceptance of the Western medication, acupuncture one of the most oldest form of traditional Chinese medicine technique has been used to treat vary form of diseases in including
chronic pain such as Fibromyalgia with or without homeopathic involvement. the recent study suggested that individually tailored acupuncture significantly lessens pain intensity in people with the chronic condition fibromyalgia(233).
In a randomised controlled multicentre trial, blinded to participants and to data analysts of a total of 164 participants aged over 17 years and diagnosed with fibromyalgia, patients with acupuncture treatment in primary care with fibromyalgia showed almelioration of pain with effect persisted at 1 year, and its side effects were mild and infrequent(235).

In support of using acupuncture for treatment of Fibromyalgia, Dr. Taw LB Dr. Henry E. said, "combination of trigger point injections and acupuncture provides improved clinical outcomes" in comparison of treatment with only acupuncture(236)But, according to the RMIT University, acupuncture improved pain and stiffness in people with fibromyalgia with only low to moderate-level evidence in comparison to no treatment and other standard therapy(234)

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References

(231) Alternative medical interventions used in the treatment and management of myalgic encephalomyelitis/chronic fatigue syndrome and fibromyalgia by Porter NS1, Jason LA, Boulton A, Bothne N, Coleman B.(PubMed)

(232) Complementary and alternative medical therapies in fibromyalgia by Sarac AJ1, Gur A.(PubMed)

(233) Fibromyalgia patients report less pain and better quality of life with acupuncture by [No authors listed](PubMed)

(234) Acupuncture for treating fibromyalgia by Deare JC1, Zheng Z, Xue CC, Liu JP, Shang J, Scott SW, Littlejohn G.(PubMed)

Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Fibromyalgia Treatment - Other oral administration medicines

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                                      Fibromyalgia

Fibromyalgia, according to the American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia in the newly proposed criteria for the classification of fibromyalgia are 1) widespread pain in combination with 2) tenderness at 11 or more of the 18 specific tender point sites(a) as a result in responding to pressure.

                        The Treatment
In conventional medicine perspective
FM usually involves females, particular to women entering stage of menopause. But it is often diagnosed both in young as well as elderly individuals. Diagnosis of pediatric FMS is a lengthy and frustrated condition affecting children and adolescents physical and emotional development, as the disease mimicked a spectrum of inflammatory joint disorders such as juvenile idiopathic arthritis (JIA), juvenile ankylosing spondylitis, etc, according to the study by Soroka Medical Center, Beer-Sheva(193)

A.2. Medications
4.  Other oral administration medicines
4.1. Cyclobenzaprine
Cyclobenzaprine is muscle relaxant used to relieve chronic fibromyalgia pain, by blocking nerve impulses sending pain sesation to your brain. According to the Laval University, the medication is highly effective in reduced chronic pain a short term in patients with fibromyalgia(222), probably through induced sleep physiology and symptoms of fibromyalgia(223).
According to drug.com the side effects are mot limit to, headache, dizziness; drowsiness, tired feeling; trouble concentrating; blurred vision, dry mouth or throat, altered sense of taste; or. nausea, upset stomach, constipation(224).

4.2. Pregabalin(see above)
4.3. Duloxetine See above
4.4  Milnacipran
Milnacipran is a serotonin–norepinephrine reuptake inhibitor used in the clinical treatment of fibromyalgia, ysed for treatment of Fibromyalgia depending to expression of key sumptoms Accoridng to the Klinikum Saarbrücken(225).

In the review of 5 studies (4138 participants) placebo-controlled, involved participants with fibromyalgia, and used titration to a target dose of 100 mg or 200 mg milnacipran, milnacipran 100 mg or 200 mg is effective for a minority in the treatment of pain due to fibromyalgia, providing moderate levels of pain relief (at least 30%) to about 40% of participants(226).

According to LX list the side effects of the medicine are not limit to, nausea, vomiting, upset stomach, bloating, dry mouth, constipation, loss of appetite, dizziness, drowsiness, tired feeling, increased sweating, headache, hot flashes (flushing),....(227).

5. Topical analgesics(capsaicin, lidocaine, salicylates) if localized neuropathic or arthritic pain
Topical analgesics, such as formulated creams, gels, and patches are applied locally to the skin and influence for treatment of Fibromyalgia's pain(228)

Most common side effects are skin irritation

6. Opioids
Opioids is an opiumlike compound binded to one or more of the three opioid receptors of the body for pain relief, including hydrocodone (e.g., Vicodin), oxycodone (e.g., OxyContin, Percocet). According to Dr. Ngian GS and research team at the Monash Medical Centre, suggested the medicine have a significant adverse effect profile, their inefficacy may be due to their inability to target the pathophysiologic processes involved in this central sensitization syndrome in patients with FM(229).

The common side effects of Opioids are not limit to sedation,dizziness, nausea, vomiting, constipation, physical dependence, tolerance, and respiratory depression,./... according to the Millennium Pain Center, Bloomington(230).

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References

(222) Comparison of amitriptyline, cyclobenzaprine, and placebo in the treatment of fibromyalgia. A randomized, double-blind clinical trial by Carette S1, Bell MJ, Reynolds WJ, Haraoui B, McCain GA, Bykerk VP, Edworthy SM, Baron M, Koehler BE, Fam AG, et al.(PubMed)

(223) The effects of cyclobenzaprine on sleep physiology and symptoms in patients with fibromyalgia by Reynolds WJ1, Moldofsky H, Saskin P, Lue FA.(PubMed)

(224) Cyclobenzaprine side effects by Drug.com

(225) Comparative efficacy and harms of duloxetine, milnacipran, and pregabalin in fibromyalgia syndrome by Häuser W1, Petzke F, Sommer C.(PubMed)

(226) Milnacipran for neuropathic pain and fibromyalgia in adults by Derry S1, Gill D, Phillips T, Moore RA.(PubMed)

(227) Side effects of Milnacipran by LXlist

(228) Compounded pain formulations: what is the evidence? by Asbill S, Sweitzer SM, Spigener S, Romero-Sandoval A.(PubMed)

(229) The use of opioids in fibromyalgia by Ngian GS1, Guymer EK, Littlejohn GO.(PubMed)

(230) Opioid complications and side effects by Benyamin R1, Trescot AM, Datta S, Buenaventura R, Adlaka R, Sehgal N, Glaser SE, Vallejo R.(PubMed)

Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Fibromyalgia Treatment - The Medications of Gabapentin, duloxetine or pregabalin if neuropathic pain

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                                      Fibromyalgia

Fibromyalgia, according to the American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia in the newly proposed criteria for the classification of fibromyalgia are 1) widespread pain in combination with 2) tenderness at 11 or more of the 18 specific tender point sites(a) as a result in responding to pressure.

                        The Treatment

In conventional medicine perspective
FM usually involves females, particular to women entering stage of menopause. But it is often diagnosed both in young as well as elderly individuals. Diagnosis of pediatric FMS is a lengthy and frustrated condition affecting children and adolescents physical and emotional development, as the disease mimicked a spectrum of inflammatory joint disorders such as juvenile idiopathic arthritis (JIA), juvenile ankylosing spondylitis, etc, according to the study by Soroka Medical Center, Beer-Sheva(193)
A.2. Medications
3. Gabapentin, duloxetine or pregabalin if neuropathic pain
Neuropathic pain is a improper healing of injure tissue causing nerve fiber damage in sending uncorrected information to other pain centers, medication used for treatment of neuropathic pain of patient with fibromyalgia may include Gabapentin, duloxetine or pregabalin.
According to the Aristotle University of Thessaloniki, in the review of data base of research literature suggested, pregabalin (PB) at a dose of 450 mg per day is most likely effective in treating FBM, although AE are not negligible(219). Other study suggested gabapentin at doses of 1200 mg or more was effective for some people with some painful neuropathic pain conditions(220), including fibromyalgia.

The most common side effects of above medicine used for treatment of neuropathic pain include bot not limit to

Dizziness, drowsiness, dry mouth, edema (accumulation of fluid), blurred vision, double vision (diplopia), weight gain, fatigue (tiredness), tremor and difficulty concentrating,... according to medicine net(221).

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References

(219) Gabapentin and pregabalin in the treatment of fibromyalgia: a systematic review and a meta-analysis by Tzellos TG1, Toulis KA, Goulis DG, Papazisis G, Zampeli VA, Vakfari A, Kouvelas D.(PubMed)

(220) Gabapentin for chronic neuropathic pain and fibromyalgia in adults by Moore RA1, Wiffen PJ, Derry S, Toelle T, Rice AS.(PubMed)

(221) side effects of pregabalin by Medicine net

Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Fibromyalgia Treatment - The Medications of Tricyclic antidepressants

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                                      Fibromyalgia

Fibromyalgia, according to the American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia in the newly proposed criteria for the classification of fibromyalgia are 1) widespread pain in combination with 2) tenderness at 11 or more of the 18 specific tender point sites(a) as a result in responding to pressure.

                        The Treatment

In conventional medicine perspective
FM usually involves females, particular to women entering stage of menopause. But it is often diagnosed both in young as well as elderly individuals. Diagnosis of pediatric FMS is a lengthy and frustrated condition affecting children and adolescents physical and emotional development, as the disease mimicked a spectrum of inflammatory joint disorders such as juvenile idiopathic arthritis (JIA), juvenile ankylosing spondylitis, etc, according to the study by Soroka Medical Center, Beer-Sheva(193)
A.2. Medications

2. Tricyclic antidepressants (if neuropathic, back or fibromyalgia pain) or tramadol; 
Fibromyalgia pain due to psychological syndrome may be treated with ricyclic antidepressants, a synthetic version of antidepressants such as selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs) and norepinephrine reuptake inhibitors (NRIs) through by blocking the serotonin transporter (SERT) and the norepinephrine
 transporter (NET)(215).  The medication through clinical expression have shown effectively for major treatment and management of fibromyalgia and other chronic pain syndromes(216).
. Dr. Lawson K said, "Tricyclic antidepressants are the most effective drugs in use so far, especially when administered in combination with other therapies (e.g., selective serotonin re-uptake inhibitors), which suggests modulation of the neurotransmitters serotonin and noradrenaline"(215).
Duloxetine, in 2 randomized, placebo-controlled, double-blind, parallel-group, 12-week trials of duloxetine in the treatment of fibromyalgia, has been shown to be an effective and safe treatment for attenuation of symptoms associated with fibromyalgia, particularly for women(217).

Most Common side effects, according to the Mayo Clinic, may include Dry mouth. Blurred vision. Constipation. Urinary retention. Drowsiness. Increased appetite leading to weight gain. .....(218)

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References

(215) Tricyclic antidepressants and fibromyalgia: what is the mechanism of action? by Lawson K1.(PubMed)

(216) A guide to the understanding and use of tricyclic antidepressants in the overall management of fibromyalgia and other chronic pain syndromes by Godfrey RG1.(PubMed)

(217) Duloxetine and other antidepressants in the treatment of patients with fibromyalgia by Arnold LM1.(PubMed)

(218) Side effects of Tricyclic antidepressants (TCAs) by Mayo Clinic