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Tuesday, 5 July 2016

Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Fibromyalgia Alternative Treatment - S-adenosylmethionine

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                                      Fibromyalgia

Fibromyalgia, according to the American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia in the newly proposed criteria for the classification of fibromyalgia are 1) widespread pain in combination with 2) tenderness at 11 or more of the 18 specific tender point sites(a) as a result in responding to pressure.

                        The Treatment


B. Alternative treatments 
Several types of alternative medicine have some potential for future clinical research. However, due to methodological inconsistencies across studies and the small body of evidence, no firm conclusions can be made at this time. we present here some of alternatives which have played an important role in human history for treatment of Fibromyalgia, according to the DePaul University(231) and Dicle University(232), in review of information regarding the efficacy of complementary and alternative medicine (CAM).
4. S-adenosylmethionine 
S-adenosylmethionine, found in almost every tissue and fluid in the body, plays an essential role involved many processes of the body, including the immune system, cell membranes, etc.....
S-adenosylmethionine may be used for treatment of symptoms of pain in patient with fibromyalgia.
Dr. De Silva V and colleagues at theUniversity of Aberdeen, said, "...., S-adenosylmethionine each showed at least one statistically significant improved outcome compared with placebo" in the study of the management of fibromyalgia(242).
Dr. Fetrow CW Dr. Avila JR insited, despite of several reviews and at least two meta-analyses agreed with efficacy as available evidence surrounding SAMe in the therapy of depression as SAMe was superior to placebo in treating depressive disorders in comparison to standard tricyclic antidepressant,as the risk profile of the supplement has not been assessed(243).

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References
(242) Evidence for the efficacy of complementary and alternative medicines in the management of fibromyalgia: a systematic review by De Silva V1, El-Metwally A, Ernst E, Lewith G, Macfarlane GJ; Arthritis Research Campaign working group on complementary and alternative medicines.(PubMed)
(243) Efficacy of the dietary supplement S-adenosyl-L-methionine by Fetrow CW1, Avila JR.(PubMed)