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Monday, 4 July 2016

Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Fibromyalgia Alternative treatments - L-carnitine

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                                      Fibromyalgia

Fibromyalgia, according to the American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia in the newly proposed criteria for the classification of fibromyalgia are 1) widespread pain in combination with 2) tenderness at 11 or more of the 18 specific tender point sites(a) as a result in responding to pressure.

                        The Treatment


B. Alternative treatments 
Several types of alternative medicine have some potential for future clinical research. However, due to methodological inconsistencies across studies and the small body of evidence, no firm conclusions can be made at this time. we present here some of alternatives which have played an important role in human history for treatment of Fibromyalgia, according to the DePaul University(231) and Dicle University(232), in review of information regarding the efficacy of complementary and alternative medicine (CAM).
3. L-carnitine
Involved in lipid metabolism, L-carnitine may be used for treatment as an althernative medicne for treatment of Fibromyalgia's symptoms. According to the, Acetyl-L-carnitine, a synthic form of L-carnitine attenuated depressive symptoms, pain, and improved the quality of life of FMS patients in comparison with the efficacy of duloxetine(240).
In a double-blind, multicenter trial comparing acetyl l-carnitine with placebo in the treatment of fibromyalgia involved 102 patients, indicate that LAC may be of benefit in patients with FMS, as it induced statistically significant in ameliorated depression and musculo-skeletal pain(241).

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References
(240) A randomised controlled trial comparing duloxetine and acetyl L-carnitine in fibromyalgic patients: preliminary data by Leombruni P1, Miniotti M1, Colonna F1, Sica C1, Castelli L2, Bruzzone M3, Parisi S3, Fusaro E3, Sarzi-Puttini P4, Atzeni F5, Torta RG1.(PubMed)
(241) Double-blind, multicenter trial comparing acetyl l-carnitine with placebo in the treatment of fibromyalgia patients by Rossini M1, Di Munno O, Valentini G, Bianchi G, Biasi G, Cacace E, Malesci D, La Montagna G, Viapiana O, Adami S.(PubMed)