Herbal Catnip, The Herbal Medicine and Plant Which Inhibits Inflammatory Diseases

By Kyle J. Norton, Master of Nutrition

Scientists may have found a herbal medicine that processes anti-inflammatory activity to protect our body from overexpression of pro-inflammatory cytokines in causing damage to healthy cells in the infectious site without reducing inflammatory cytokine activities.

Inflammation is a natural reaction of the immune system which initial protein signaling in stimulated production of inflammatory expression against foreign organisms invasion.

However, under the infectious condition, systematic inflammatory response in some cases may over overact, leading to overproduction of pro-inflammatory cytokines such as TNF alpha,.... and  

Interleukins (IL) 1 and 6. which are a group of cytokines expressed by white blood cells of the immune system.

The Encyclopaedia Britannica wrote, "Like other cytokines, interleukins are not stored within cells but are instead secreted rapidly, and briefly, in response to a stimulus, such as an infectious agent. Once an interleukin has been produced, it travels to its target cell and binds to it via a receptor molecule on the cell’s surface" and  "This interaction triggers a cascade of signals within the target cell that ultimately alter the cell’s behavior".

Catnip is also known as catswort, or catmint, a plant of Nepeta, belonging to the family of Lamiaceae, native to Europe and Asia. 

The herb has been used in herbal medicine as an insect repellant and to treat digestive disorders, children restlessness and nervousness, fevers, cold and flu, skin irritation stimulates sweating, promote menstruation, etc..

Ingredients
Besides the major constituent of terpenoid nepetalactone, the herb also contains α-Pinene, β-Pinene, Cyclohexen-1-yl-methyl ketone, Triplal, Thymol, Nepetalactone, Nepetalactone, etc.

In chronic related inflammation disease induced to 24 male Wister rats weighing 225 ± 25 gm, essential oil of catnip at the doses of 50 mg/kg, 100 mg/kg and 200 mg/kg researchers found that administered doses intraperitoneally exert significant effects in reduced paw edema by alleviating symptoms of both the acute and chronic forms of nociception, through its anti-inflammatory effect(1).

Dr. Ali T, the lead scientists at the Bangabandhu Sheikh Mujib Medical University, said, " NP 200 mg/kg reduced the pain sensation in the tail flick (p <0.01) and formalin test (p <0.001 in both phases). In paw edema test, NP 100 and 200 mg/kg significantly reduced the inflammation (p <0.01 and p <0.05)"(1).

The efficacy of catnip in inhibited chronic inflammation of experimental rats was attributed to chemical constituents 4aα,7α,7aβ-nepetalactone and 1,8-cineole that form major parts in phytochemicals of the herb.

The Tarbiat Modares University study also showed that Nepeta crispa essential oil enhances anti-inflammatory effects in the formalin-induced paw inflammation model and significantly reduced the paw edema(2).

More precisely, the essential oil injection ameliorated acute pain in animal models, including the tail-flick (p < 0.001) in the first phase of the formalin test (p < 0.01) through the production of analgesia(2).

In the late phase of the formalin test, the essential oil significantly reduced the pain-induced behavior against chronic pain(2).

Furthermore, in the study of extracts and isolated compounds tested against calcineurin, scientists showed that herbal catnip has a direct interaction with calcineurin through anti-inflammatory activity via modulation of T-cell in the mediation of inflammation(3).

Dr. Prescott TA and the research team at the Royal Botanic Gardens suggested, " Calcineurin inhibition should be considered as a potential mode of action when investigating the immunomodulatory activity of caffeoyl phenyle anoid glycoside containing plants"(3).

The findings suggested that herbal catnip may be considered as a functional food for treatment of acute and chronic inflammation without reducing the function of the immune system in protected our body against infection.

However, large sample size and multi-center clinical studies during the course of human consumption are necessary to reaffirm the catnip anti-inflammatory possibility.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Evaluation of the antinociceptive and anti-inflammatory effects of essential oil of Nepeta pogonosperma Jamzad et Assadi in rats by Ali T, Javan M, Sonboli A, Semnanian S.(PubMed)
(2) Antinociceptive and anti-inflammatory activities of the essential oil of Nepeta crispa Willd. in experimental rat models by Ali T, Javan M, Sonboli A, Semnanian S.(PubMed)
(3) Direct inhibition of calcineurin by caffeoyl phenylethanoid glycosides from Teucrium chamaedrys and Nepeta cataria by Prescott TA, Veitch NC, Simmonds MS.(PubMed)

(4) Interleukin PROTEIN by Encyclopaedia Britannica

How to Protect Your Joints (Articulations) Before and After 60

By Kyle J. Norton, Master of Nutrition

Scientists may have found a natural herb, namely Cat's claw in suppressing the onset of osteoarthritis without inducing any adverse effects, some studies suggested

Osteoarthritis is a group of diseases involved progressive degeneration of joints, including articular cartilage and subchondral bone.

According to statistic, osteoarthritis(OA) is one of the most common forms of arthritis disorder, affecting adults 60 years of age or older in the United States.

Approximately, over 25 million of US population who are adults 60 years of age or older are infected by symptomatic knee OA, including  10% of men and 13% of women.

However, according to University of Porto Medical School indicated that one must understand the differences in prevalence and incidence estimates of osteoarthritis (OA), according to case definition, in the knee, hip and hand joints.

Conventional medicine, today in the management of osteoarthritis (OA) focuses on pain relief and improved physical function through pharmacological, nonpharmacological, and surgical treatments without mentioning how to cure the disease.

 There is evidence suggested that the disease is associated with the inflammation, breakdown, and eventual loss of cartilage in the joints. But what causes the chronic inflammatory of osteoarthritis is debatable?

Some researchers suggested that the process of wear and repair, nutrient deficiency,......and overload and damage of cartilage due to aging or damage are the possible actually cause of osteoarthritis.

The severity symptoms of osteoarthritis, according to experts include pain in joints of the hand, knee and hip and spine. If you experience the above symptoms, you may already have osteoarthritis.

.Cat's claw found in in the tropical jungles of South and Central America, is a genus Uncaria, belonging to the family Rubiaceae.

The specific herbal medicine has been used in traditional medicine over two thousand years as a tonic, contraceptive, anti-inflammatory, and infectious agent, and to treat diarrhea, rheumatic disorders, acne, diabetes, cancer and diseases of the urinary tract, etc..

Chemical constituents
The chemical constituents of Cat's claw include ajmalicine, akuammigine, campesterol, catechin, carboxyl alkyl esters, chlorogenic acid, cinchonain, corynantheine, corynoxeine, daucosterol, epicatechin, harman, hirsuteine, hirsutine, iso-pteropodine, etc.

In the study to understand the effect of Cat's claw isolated active compounds against the pivotal molecular targets involved in inflammation and the joint destruction process and in summarized their 's claw toxicities and efficacy, researchers at the Case Western Reserve University, showed that application of herbal Cat's claw exerts a positive effect in alleviation pain with no adverse effect(1).

Dr. Akhtar N, the lead author after taking account of other co and confounders said, " (Although) Limited in vitro and in vivo evidence is available for cat's claw and Indian olibanum,... There is strong clinical evidence of the effectiveness of devil's claw in pain reduction" and " No serious side effects have been reported for any..... herbs" (1).

According to the study of "Devil's claw extract as an example of the effectiveness of herbal analgesics", Doloteffin (extraction solvent water) a botany herbal preparation included extracted with 60% ethanol of Cat's claw have a proven effectiveness similar to those of conventional painkiller or synthetic analgesics for treatment painful lower back or arthritic pain(2)..

Dr. Chrubasik S. at Institut für Rechtsmedizin der Universität Freiburg, said, " From an evidence-based view, extract with at least 50 mg harpagoside in the daily dose should be recommended for the treatment of pain" and "Treatment with devil's claw extract is associated with a lower risk of adverse events than treatment with synthetic analgesics, and may contribute in the majority of patients to the relief of pain"(2).

This effectiveness may coincide with the use of the herb in herbal medicine for thousands of year in treating disorders such as arthritis, gastritis, and osteoarthritis(3).

Truly, The mechanisms of cat's claw in the treatment of osteoarthritis were attributed to the antioxidants and its inhibition of TNF-alpha.

Tumor necrosis factor α is a cell signaling protein (cytokine) involved systemic inflammation that protects our body against foreign organism infection in acute phase reaction.

Unfortunately, the study in reviews the database by the University of Southampton, raised the question of the methodological quality of the existing clinical trials and suggested that clinical evidence to date cannot provide a definitive answer to the two questions posed, although these trials may provide certain supports for the effectiveness of the herb(4).
* Does it work?
* And (2) is it safe?

Taking all together, Cat's claw may have a profound and substantial effect similar to those of conventional medicine such as acetaminophen (Tylenol) and nonsteroidal anti-inflammatory drugs (NSAIDs). Aspirin, naproxen (Aleve), and ibuprofen in ameliorated osteoarthritis pain with little or no side effects(3).

However, intake of Cat's claw supplement only is prescribed by herbalists as an overdose may cause acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Current nutraceuticals in the management of osteoarthritis: a review by Akhtar N1, Haqqi TM. (PubMed)
(2) [Devil's claw extract as an example of the effectiveness of herbal analgesics].[Article in German]
by Chrubasik S.(PubMed)
(3) Cat's claw: an Amazonian vine decreases inflammation in osteoarthritis by Hardin SR.(PubMed)
(4) Devil's Claw (Harpagophytum procumbens) as a treatment for osteoarthritis: a review of efficacy and safety by Brien S1, Lewith GT, McGregor G.(PubMed)
(5) Osteoarthritis by Kyle J. Norton

Unripe Papaya Whole Food Which Averts The Onset of Diabetes, Scientists Found

By Kyle J. Norton

Papaya may be used as a functional food to inhibit early onset and treatment of diabetes, some scientists suggested.

Diabetes is a medical and chronic condition characterized by abnormally high levels of sugar (glucose) in the blood caused by pancreas inability in produced insulin.

In other words, diabetes is a result of absence or insufficient production of insulin by the pancreas. The condition is also caused by the inability of the body to properly use of insulin, leading to insulin resistance.

According to the statistic produced by the Canadian Diabetes Association, approximately, 17%
of Canadian, over 12 years of age are diagnosed with diabetes.

Interestingly, diabetes affects both genders up to age 64. The prevalence does not increase significantly for those aged 65 and older.

Unlike type 1 diabetes which is caused by the immune system attacking the cells in the pancreas that make insulin, leading to the body without enough insulin to function normally, type 2 diabetes is caused by unhealthy diet and lifestyle.

Obesity and increasing age are 2 of many risk factors that can elevate the risk of type 2 diabetes. 

Symptoms of type 1 and 2 diabetes, according to Medicine Net include increased urine output, excessive thirst, weight loss, hunger, fatigue, skin problems slow-healing wounds, yeast infections,..... and tingling or numbness in the feet or toes(6).

If you experience some of the above symptoms, please see a doctor to rule out the possibility.

Papaya is a species of Carica Papaya, belongings to the family Caricaceae and native to the tropics of the Americas, and was first cultivated in Mexico and several centuries


Chemical constituents
Alkaloids, Cardenolides, Anthraquinones, Saponins, Tannin, phenol, flavonoid, anthocyanin, Benzyl glucosinolate, benzylisothiocyanate, 5-(Hydroxymethyl)-2-furancarboxaldehyde, 2,3-dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one and 1,3-dihydroxy-2-propanone, etc.(a).


Water extract from papaya isolated from unripe pawpaw (Carica papaya Linn) fruit, exerted a significant effect in inhibition of enzymes, α-amylase and α-glucosidase that linked to type 2 diabetes, in sodium nitroprusside (SNP)-induced lipid peroxidation mice model and a dose-dependent manner(1).

Combination of the flesh, seed, and peel in equal amounts produced the highest inhibitory effect on α-amylase and α-glucosidase activities compared to other preparations.

Dr. Oboh G, the lead authors in the study said, "Strong inhibitory activities of the unripe pawpaw fruit against key enzymes linked to type 2 diabetes and SNP-induced lipid peroxidation in rat pancreas could be part of the mechanism by which unripe pawpaw is used in the management/prevention of diabetes mellitus in folk medicine"(1).

Truly, in the preparation of individual aqueous extract of the unripe pawpaw fruit parts; peel (PG), seed (SG), flesh (FG), flesh with peel (FPG) and a combination of equal amount of all parts (CG), the Federal University of Technology at the end of experiment indicated that on Fe²⁺-induced lipid peroxidation in rat pancreas, application of the prepared extracts phenolic compounds inhibited oxidative stress through their antioxidant activities(2).

According to Universidad Juárez Autónoma de Tabasco (UJAT), unripe papaya preparations not only exert hypoglycemic effects in both animals and humans studies but also help islet regeneration,   preservation of cell size and prevented hepatocyte disruption(3).

In fact, the aqueous extract of Carica papaya also significantly decreased blood glucose levels in diabetic rats and decreased cholesterol, triacylglycerol, and amino-transferases blood levels without changing the levels of plasma insulin levels in diabetic rats(4).

 In short-term supplementation of a fermented papaya, showed to exhibit its effect in the management of diabetes and for those at risk for cardiovascular disease, neurological disease and other conditions worsened by overt inflammation and oxidative stress(5).

These findings suggested that all parts of unripe papaya have a strong and profound effect in inhibition of diabetic onset and treatment of type 2 diabetes.

However, a large sample size and multi-center clinical trial on human consumption on the course of the disease onset are necessary to confirm the unripe papaya anti-diabetes possibility.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(a) Chemical composition and bioactivity of dried fruits and honey of Ficus carica cultivars Dottato, San Francesco and Citrullara by Loizzo MR1, Bonesi M, Pugliese A, Menichini F, Tundis R.(PubMed)
(1) Inhibition of key enzymes linked to type 2 diabetes and sodium nitroprusside-induced lipid peroxidation in rat pancreas by water-extractable phytochemicals from unripe pawpaw fruit (Carica papaya). by Oboh G, Olabiyi AA, Akinyemi AJ, Ademiluyi AO.(PubMed)
(2) Inhibitory effect of aqueous extract of different parts of unripe pawpaw (Carica papaya) fruit on Fe²⁺-induced oxidative stress in rat pancreas in vitro by Oboh G1, Olabiyi AA, Akinyemi AJ.(PubMed)
(3) Hypoglycemic effect of Carica papaya leaves in streptozotocin-induced diabetic rats by Juárez-Rojop IE1, Díaz-Zagoya JC, Ble-Castillo JL, Miranda-Osorio PH, Castell-Rodríguez AE, Tovilla-Zárate CA, Rodríguez-Hernández A, Aguilar-Mariscal H, Ramón-Frías T, Bermúdez-Ocaña DY.(PubMed)
(4) Antihyperglycemic and hypolipidemic activities of aqueous extract of Carica papaya Linn. leaves in alloxan-induced diabetic rats by Maniyar Y1, Bhixavatimath P(PubMed)
(5) Effects of a short term supplementation of a fermented papayapreparation on biomarkers of diabetes mellitus in a randomized Mauritian population by Somanah J1, Aruoma OI, Gunness TK, Kowelssur S, Dambala V, Murad F, Googoolye K, Daus D, Indelicato J, Bourdon E, Bahorun T.(PubMed)
(6) Diabetes Symptoms, (Type 1 and Type 2) by Medicine Net

* White Button Mushroom, The Whole Food That Suppresses Onset of Arthritis

 By Kyle J. Norton

Mushroom may process a significant effect in inhibited all forms of arthritis, some scientist suggested.

Arthritis is a class of over 100 medical conditions, affecting people of all ages, sexes and races.

Most common cause of arthritis in aging is the degeneration of cartilage, the slick, cushioning surface on the ends of bones that has bee worn away, causing bone rubs against bone, in induction of pain, swelling and stiffness.

Depending to severity of osteoarthritis, patients may experience symptoms that surround the joints in hands, knees, hips and spine, such as pain in the joint during or after movement, muscle and feet tenderness, stiffness, loss of flexibility. ... and grating sensation.

The other most common types of arthritis is Rheumatoid arthritis (RA) that is a long-term autoimmune disorder, inducing warm, swollen, and painful joints.

According to statistic, approximately, 50 million adults and 300,000 children have some forms or types of arthritis.

The CDC statistic from 2013–2015, stated that an estimated 54.4 million US adults (22.7%) annually have ever been told by a doctor that they have some form of arthritis, rheumatoid arthritis, gout, lupus, or fibromyalgia(2).

The prevalent risk factor is also depended to where you live. For example, the percentage of adults with arthritis varies by state, ranging from 17.2% in Hawaii to 33.6% in West Virginia in 2015(2).

The John Hopskins arthritis center suggested, " Data from 32,322 adults in 11 states from the 1998 Behavioral Risk Factor Surveillance Survey (BRFSS), a health survey given annually in the United States, indicates that adults with arthritis report significantly greater HRQL impairment compared to adults without arthritis"(3).

Mushroom is a standard name of white button mushroom, the fleshy, spore-bearing fruiting body of a fungus produced above ground on soil or on its food source,

It is a genus A. Muscaria and belonging to the family Amanitaceae and has been cultivation in many cultures all over the world for foods and health benefits.

Certain medical mushroom have been used in Chinese medicine to promote immunomodulatory activity for the treatment and/or prevention of chronic diseases.

Chemical constituents
Astraodorol, Psilocybin, Lectin, adustin, ribonuclease, nicotine, 2-hydroxy-4-methoxy-6-methylbenzoic acid, orsellinic acid, melleolide, ergosterol, genistein, daidzein, daucosterol, genistin, uracil and D-mannitol(a).

In the study to compared the effect of white button mushroom, a common American diet component WBM and shiitake mushrooms (SM) on collagen-induced arthritis (CIA) in 8-wk-old female dilute brown non-agouti mice, researchers found that

* In compared to control, both WBM and SM exert a strong effect in reduced the CIA index from 5.11 ± 0.82 to 3.15 ± 0.95 (P = 0.06).

* Oral injection of SM, WBM and control diet to immunizing mice with 100 µg bovine collagen followed by 50 µg LPS on d 20 post-collagen injection. shows a significant reduction with CIA index by 29% in compared to 23 % WBW and 58% of control.

* Both types of mushrooms reduced plasma, however only SM increased plasma IL-6 substantially. The CIA index was positively correlated with sICAM1 (r = 0.55; P < 0.05) in expression on endothelial cells and cells of the immune system.

Tumor necrosis factor alpha TNFα is a protein with function to protect our body in regulation of immune cells in response to  system inflammation via IL1 & IL6 producing cells. Over expression of TNFα may induce chronic inflammation to local site, leading to destruction of cells and tissue, such as arthritis.

IL1 & IL6 are interleukins that act as anti-inflammatory cytokines normally and pro inflammatory cytokines when the body is under attack by foreign invasive organisms.

Dr. Chandra L, at the end the the experience said, "Although both types of mushrooms reduced plasma TNFα (34%, WBM; 64%, SM), only SM increased plasma IL-6 by 1.3-fold (P < 0.05)".

These results suggested that both mushroom have a strong effect in stimulated immune system against infection of the joint of patients with arthritis CIA positive induced by injection tested mice.

However, application SM cause over production of IL-6 that can lead to healthy cells death and forming of scars of the infectious site in compared to WBM.

People who have arthritis or are at higher risk of the disease  may want to add a portion of white button mushroom WBM into diet.

Taking altogether, white button mushroom may be considered as a functional food that can help to manage and treat arthritis.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

References
(a) [Chemical constituents from fungus Armillaria mellea]. by [Article in Chinese] by Yuan XL1, Yan LH, Zhang QW, Wang ZM.(PubMed)
(1) White button and shiitake mushrooms reduce the incidence and severity of collagen-induced arthritis in dilute brown non-agouti mice by Chandra L1, Alexander H, Traoré D, Lucas EA, Clarke SL, Smith BJ, Lightfoot SA, Kuvibidila S.(PubMed)
(2) Arthritis-Related Statistics(CDC)
(3) Arthritis and Health-related Quality of Life by Kevin Fontaine, Ph.D(John Hopskins Arthritis Center)

* The Natural Weight Loss Whole Foods Recommended By Scientists

By Kyle J. Norton

The prevalence of extreme overweight and obesity has caused concerns of scientific community in the South East Asian population, due unhealthy diet and life style change over 2 decades of economic prosperity.

Overweight and obesity have reached epidemic proportions in many Asian countries, affecting even younger age than in Western populations with economic burden in the development of obesity-related disorders such as diabetes, hypertension, and cardiovascular diseases(1).

 One of six Malaysian are either extreme overweight or obese, according to Datin Paduka Santha Kumari, chairman of the Selangor branch of the Malaysian Diabetes Association.

And,  according to global health observatory, at least 2.8 million people die each year as a result of being overweight or obese, and an estimated 35.8 million (2.3%) of global DALYs are caused by overweight or obesity, worldwide(2).

Epidemiological studies, linking herbal medicine, foods and vitamins in preventing and treating these diseases have been inconclusive(a)

Some researchers suggested that intake of certain herbal medicine may enhance appetite suppression.

However,  according to the Georgetown University Medical Center, average daily food intake was decreased only with the herbal formulation, not the phenylpropanolamine (PPA) at the low and high doses, in comparison of the effectiveness among herbal formulation and a commonly available(3).

Other researchers insisted that using herbs and supplements to induce weight loss should be taken with care, as a considerable number of reports have been published on hepatotoxicity associated with herbal products attributed with weight-reducing properties(4)(5)(6)(7).

The College of Medicine, The Ohio State University insisted that various dietary, lifestyle, and psychologic factors are involved in the etiology of Prameha, particularly in relation to disturbances in fat and carbohydrate metabolism(8), without effective management, obtaining a workable weight loss plan may be extremely difficult.

Epidemiological studies, linking certain foods in reduced weight loss for obese individual have produced certain positive results, but researchers emphasized that weight loss can not be in the expenses of intake of nutrients(30a).
1. Oats
Oat is a species of cereal grain grown for its seed and was first cultivated in Europe but is now grown all over the world, especially in Scotland and England.

It is one of good crop to plant in the poor soil after crops are harvested in the Fall(30).

Oat, rich in beta-glucan, may hold a magic power in regulation of metabolism and liver-protecting effect.

According to Chung-Shan Medical University, consumption of oat reduced obesity, abdominal fat, and improved lipid profiles and liver functions with no adverse effects(31).

Whole-grain ready-to-eat oat cereal, in a randomized study of 144 Free-living, overweight and obese adults (N=204, body mass index 25 to 45) with baseline LDL cholesterol levels 130 to 200 mg/dL, had favorable effects on fasting lipid levels and waist circumference(32).

Other study suggested that at-derived beta-glucan, combined with moderate exercise also improved lipid profile and caused a decrease in weight(33).

2. Salmon
Salmon is the common name for Salmonidae. They are anadromous, born in fresh water, migrate to the ocean, then travel thousands of miles in the deep sea cold water throughout their life cycle and within to five years returning to the exacted location where they were born to reproduce and die(34).

Dietary salmon oil, in rat study showed to reduced weight loss of CXB-E and -H tested mice, but induced with weight gain in recombinant inbred strains.

This findings may suggested that body weight response to salmonoil feeding is controlled by multiple genes(35).

A novel oral form of salmoncalcitonin (sCT), according to the study at 1Nordic Bioscience, also showed to improve fasting and postprandial glycemic control and insulin sensitivity and may be considered as a promising agent for the treatment of obesity-related insulin resistance and type 2 diabetes patients(36)(37).

3. Brown rice
Brown rice or unpolished rice is a kind of whole, natural grain with very brown color of which only the outermost layer of the rice kernel are removed, thus preventing the lost of nutrients(38).

The study of the weigh effect of brown rice on metabolic parameters in type 2 diabetes, showed a positive effect of consumption of the brown rice(LB) in association with a decreased waist circumference in type 2 diabetic patients(39).

 Other randomized study of forty women between 20 and 35 years of age in the comparison of white rice and mixed rice of weight control, including brown rice, indicated that meal replacement with mixed rice was superior to replacement with white rice in weight control, improving antioxidant enzyme activity(40).

4. Chicken
Chicken are domesticated fowl belonging to the subspecies of Gallus domesticus and is raised all over the world for its delicious meats and eggs.

It can be roasted, broiled, grilled or poached into a very delicious, tasteful and nutritious meal(41).

In the comparison of weight loss and total lipid profile changes in overweight women consuming beef or chicken, researchers at 1Rippe Lifestyle Institute, Shrewsbury showed a interest result of weight loss and improved lipid profile can be accomplished through diet and exercise, regardless to dietary protein source including lean beef or chicken(42).

But the study at University of Navarra, showed a opposite result in the study of frequent consumption of selenium-enriched chicken meat(43), it may be the result of the presence of antioxidant selenium in the meat.

5. Water
According to Virginia Tech, consuming 500 ml water prior to each main meal may lead to greater weight loss than a hypocaloric diet alone in middle-aged and older adults, because of it acutely reduces meal energy intake(EI)(44) but not younger subjects(45).

The Choose Healthy Options Consciously Everyday (CHOICE) randomized clinical trial, suggested that replacing caloric beverages with water or diet beverages induced 2% to 2.5% weight loss(46).

6. Nuts
Dietary consumption of nuts with rich sources of multiple nutrients is associated with health benefits and weight loss,epidemiologically. but in well-controlled nut-feeding trials, no changes in body weight were observed(47).

Pistachio nuts, a member of the cashew family, can be consumed as a portion-controlled snack for individuals restricting calories to lose weight without concern that pistachios will cause weight gain(48).

7. Green tea
Green tea contains more amount of antioxidants than any drinks or food with the same volume, and is the leaves of Camellia sinensis, undergone minimal oxidation during processing, originated from China.

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years.

Because of their health benefits, they have been cultivated for commercial purposes all over the world.

According to Maastricht University, caffeine intake and green teasupplementation are associated to improved weight maintenance, partly through thermogenesis and fat oxidation, in a randomized placebo-controlled double blind parallel trial in 76 overweight and moderately obese subjects(49).

Catechins the antioxiands found abundantly in green tea, significantly decreased body weight and significantly maintained body weight after a period of weight loss, depending to the moderators of habitual caffeine intake and ethnicity(50).

 In a high-protein diet, green tea-caffeine mixture, failed to exert the same effect on body weightmaintenance(51).

8. Coffee
Coffee made from the roasted seeds of the genus Coffee, belongings to the family Rubiaceae native to southern Arabia.

In a randomized, double-blind, placebo-controlled, linear dose, crossover study, green coffee extract, consistent with human and animal studies and a meta-analysis may be an effective nutraceutical in reducing weight in preobese adults(52).

Mannooligosaccharides (MOS), extracted from coffee, exhibited a potential functional use for weight management and improvement in adipose tissue distribution, but varying in gender(53).

Unfortunately, green coffee extract (GCE), according to University of Exeter, in reviews of the effect against weight loss of existed data, showed a significant poor methodological quality and suggested that more rigorous trials are needed to assess the usefulness of GCE as a weight losstool(54).

Other study, reported a case of Brazil Potent Slimming Coffeeand possibly also other weight-loss products may be contaminated with sibutramine and as a result cause severe adverse reactions after stabbing herself in the stomach with a knife(55).

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

References
(1) Rising Burden of Obesity in Asia by Ambady Ramachandran and Chamukuttan Snehalatha(Journey of Obesity)
(2) Obesity - Situation and trends(WHO)
(3) Influence of a combination of herbs on appetite suppression and weight loss in rats by Talpur NA1, Echard BW, Manohar V, Preuss HG.(PubMed)
(4) [Hepatotoxicity induced by herbs and medicines used to induce weight loss].[Article in Spanish]by Herrera S1, Bruguera M.(PubMed)
(5) A case report of adult lead toxicity following use of Ayurvedic herbal medication by Breeher L1, Gerr F, Fuortes L.(PubMed)
(6) [Chronic lead intoxication associated with Ayurvedic medication].[Article in Dutch] by Kanen BL1, Perenboom RM.(PubMed)
(7) Potential toxicity of caffeine when used as a dietary supplement for weight loss by Pendleton M1, Brown S, Thomas C, Odle B.(PubMed)
(8) Multinutrient supplement containing ephedra and caffeine causes weight loss and improves metabolic risk factors in obese women: a randomized controlled trial by Hackman RM1, Havel PJ, Schwartz HJ, Rutledge JC, Watnik MR, Noceti EM, Stohs SJ, Stern JS, Keen CL.(PubMed)
(30) #Healthy #Foods - Oats ((Avena sativa) (Health tips for better living and living health)
(31a) Association between mood and diet quality in subjects with metabolic syndrome participating in a behavioural weight-loss programme: A cross-sectional assessment by Perez-Cornago A, Zulet MA, Martinez JA.(PubMed)
(31b) Dietary quality-adherence to the dietary guidelines in Tehranian adolescents: Tehran Lipid and Glucose Study by Mirmiran P1, Azadbakht L, Azizi F.(PubMed)
(31) Oat prevents obesity and abdominal fat distribution, and improves liver function in humans by Chang HC1, Huang CN, Yeh DM, Wang SJ, Peng CH, Wang CJ.(PubMed)
(32) Whole-grain ready-to-eat oat cereal, as part of a dietary program for weight loss, reduces low-density lipoprotein cholesterol in adults with overweight and obesity more than a dietary program including low-fiber control foods by Maki KC1, Beiseigel JM, Jonnalagadda SS, Gugger CK, Reeves MS, Farmer MV, Kaden VN, Rains TM.(PubMed)
(33) Oat-derived beta-glucan significantly improves HDLC and diminishes LDLC and non-HDL cholesterol in overweight individuals with mild hypercholesterolemia, Reyna-Villasmil N1, Bermúdez-Pirela V, Mengual-Moreno E, Arias N, Cano-Ponce C, Leal-Gonzalez E, Souki A, Inglett GE, Israili ZH, Hernández-Hernández R, Valasco M, Arraiz N.(PubMed)
(34) #Healthy #Foods - Seafoods - Salmon (Healthy tips for better living and living health)
(35) Genetically determined body weight loss in mice fed diets containing salmon oil by LeBoeuf RC1, Veldee MS.(PubMed)
(36) Oral salmon calcitonin improves fasting and postprandial glycemic control in lean healthy rats by Feigh M1, Nielsen RH, Hansen C, Henriksen K, Christiansen C, Karsdal MA.(PubMed)
(37) A novel oral form of salmon calcitonin improves glucose homeostasis and reduces body weight in diet-induced obese rats by Feigh M1, Henriksen K, Andreassen KV, Hansen C, Henriksen JE, Beck-Nielsen H, Christiansen C, Karsdal MA.(PubMed)
(38) #Healthy #Foods - Whole Grain - Brown rice or Hulled rice's(Health tips for beter living and living health)
(39) Intake of brown rice lees reduces waist circumference and improves metabolic parameters in type 2 diabetes by Kim TH1, Kim EK, Lee MS, Lee HK, Hwang WS, Choe SJ, Kim TY, Han SJ, Kim HJ, Kim DJ, Lee KW.(PubMed)
(40) Meal replacement with mixed rice is more effective than white rice in weight control, while improving antioxidant enzyme activity in obese women by Kim JY1, Kim JH, Lee da H, Kim SH, Lee SS.(PubMed)
(41) #Healthy #Foods - Chicken (Gallus gallus domesticus)(Health tips for btter living and living health)
(42) Weight loss and total lipid profile changes in overweight women consuming beef or chicken as the primary protein source by Melanson K1, Gootman J, Myrdal A, Kline G, Rippe JM.(PubMed)
(43) Frequent consumption of selenium-enriched chicken meat by adults causes weight loss and maintains their antioxidant status by Navas-Carretero S1, Cuervo M, Abete I, Zulet MA, Martínez JA.(PubMed)
(44) Water consumption increases weight loss during a hypocaloric diet intervention in middle-aged and older adults by Dennis EA1, Dengo AL, Comber DL, Flack KD, Savla J, Davy KP, Davy BM(PubMed)
(45) Pre-meal water consumption reduces meal energy intake in older but not younger subjects by


Van Walleghen EL1, Orr JS, Gentile CL, Davy BM.(PubMed)
(46) Replacing caloric beverages with water or diet beverages for weight loss in adults: main results of the Choose Healthy Options Consciously Everyday (CHOICE) randomized clinical trial by Tate DF1, Turner-McGrievy G, Lyons E, Stevens J, Erickson K, Polzien K, Diamond M, Wang X, Popkin B.(PubMed)
(47) Nut consumption and body weight by Sabaté J.(PubMed)
(48) Pistachio nuts reduce triglycerides and body weight by comparison to refined carbohydrate snack in obese subjects on a 12-week weight lossprogram by Li Z1, Song R, Nguyen C, Zerlin A, Karp H, Naowamondhol K, Thames G, Gao K, Li L, Tseng CH, Henning SM, Heber(PubMed)
(48) Impact of peanuts and tree nuts on body weight and healthy weight loss in adults by Mattes RD1, Kris-Etherton PM, Foster GD.(PubMed)
(49) Body weight loss and weight maintenance in relation to habitual caffeine intake and green tea supplementation by Westerterp-Plantenga MS1, Lejeune MP, Kovacs EM.(PubMed)
(50) The effects of green tea on weight loss and weight maintenance: a meta-analysis by Hursel R1, Viechtbauer W, Westerterp-Plantenga MS.(PubMed)
(51) Green tea catechin plus caffeine supplementation to a high-protein diet has no additional effect on body weight maintenance after weight loss by Hursel R1, Westerterp-Plantenga MS.(PubMed)
(52) Randomized, double-blind, placebo-controlled, linear dose, crossover study to evaluate the efficacy and safety of a green coffee bean extract in overweight subjects by Vinson JA1, Burnham BR, Nagendran MV.(PubMed)
(53) A weight-loss diet including coffee-derived mannooligosaccharides enhances adipose tissue loss in overweight men but not women, by St-Onge MP1, Salinardi T, Herron-Rubin K, Black RM.(PubMed)
(54) The use of green coffee extract as a weight loss supplement: a systematic review and meta-analysis of randomised clinical trials by Onakpoya I1, Terry R, Ernst E.(PubMed)
(55) [Life-threatening psychosis caused by using sibutramine-contaminated weight-loss coffee].

[Article in Dutch] by Bertholee D1, ter Horst PG, Wieringa A, Smit JP.(PubMed)

* Coffee, The Beverage That Is Associated to Type I and 1.5 Diabetes' Risk, Scientists Say

By Kyle J. Norton

Intake of coffee in adulthood may increase risk of latent autoimmune and type 1 diabetes in children and adults, a study of Institute of Environmental Medicine, Karolinska Institutet suggested.
Latent autoimmune diabetes in adults (LADA), similar to type 1 diabetes, is a slow progressing form of autoimmune diabetes. The disease is caused by pancreas inability to produce enough insulin, because of slowly die off of insulin-producing cells in the pancreas.

LADA is also known as type 1.5 diabetes, because the disease has characteristics of both type 1 (autoimmune in nature) and type 2 diabetes. 

Therefore, LADA shares the same risk factors and symptoms similar to those type 1 and 2 diabestes.

Dr. Priyanka P. Brahmkshatriya, the lead scientist in the study of  "Characteristics and Prevalence of Latent Autoimmune Diabetes in Adults (LADA)" said, "Various parameters such as age at onset, duration of diabetes, gender, basal metabolic index (BMI), type of diabetes, family history, HbA1c levels, cholesterol levels, and current treatment regimen were evaluated and correlated with type 1 and type 2 diabetes."

And symptoms may also include Unusual thirst. Frequent urination, weight loss despite an increase in appetite. blurred vision, bausea and vomiting,.......... irritability and mood changes.

Some researchers suggested that increased fatty fish consumption may reduce the risk of LADA, possibly through effects of marine-originated omega-3 fatty acids(5).

Unlike type 2 diabetes, patients with LADA do not respond well to seems to lifestyle and medication as in type-2 diabetes in long term. Medicine used for treatment of type 2 diabetes do not halt or slow the progression of loss of pancreas beta cells.

According to the Indian Express, "Dietary recommendations to manage LADA include slowing progression of the disease, management of body weight and maintaining optimum blood sugar levels. A high fibre, low glycemic index diet with anti-inflammatory foods and nutrients has been found to be useful".

However, people with LADA will eventually become insulin dependent.

Coffee, a popular and social beverage all over the world, particular in the West, is a drink made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.

In a population-based case-control study with incident cases of adult onset (≥ 35 years) diabetes, including 245 cases of latent autoimmune diabetes (glutamic acid decarboxylase antibody positive), 759 cases of Type 2 diabetes (glutamic acid decarboxylase antibody negative), together with 990 control subjects without diabetes, randomly selected from the population, researchers after inspection of the returned questionnaire, found that coffee intake may be associated with an increased risk of high glutamic acid decarboxylase antibody latent autoimmune diabetes in adults.

The relative odd ratio of onset of these population was 1.11 in compared to non drinkers.

The risk of disease development increased by 15.2% (P = 0.0268) for every additional cup intake.

Dr. Löfvenborg JE, the lead author said, " coffee may be associated with development of autoimmunity and possibly an increased risk of more Type 1-like latent autoimmune diabetes in adults".

More importantly, in the review of the association between coffee intake, its influence on the immune system and the insurgence of the most relevant autoimmune diseases conducted by the joint study lead by the Tel-Aviv University, scientists discovered that coffee intake exerts a selectively both in increased(rheumatoid arthritis (RA) and type 1 and 1.5 diabetes mellitus (T1 and 1.5 DM)) and decreased(multiple sclerosis, primary sclerosing cholangitis, and ulcerative colitis) risk of some auto immune diseases.


Particularly in type 1 diabetes, Dr. Sharif K, the lead author said, "Coffee intake led to a decrease in insulin sensitivity in T1DM" and " coffee consumption was shown to influence disease course and management options".

Remarkably, in the study of some diabetic children younger than 15 years, and diagnosed from September 1986 to the end of April 1989, with 600 newly diagnosed and 536 randomly selected population-based children, researchers postulated that risk for type 1 diabetes were increased in the children who consumed at least 2 cups of coffee daily in compared to other groups.even after adjusting to other odd factors.

The finding evidences suggested that coffee intake daily and regular may have significant impact in increased development of type 1 and 1.5  diabetes in children and adults regardless amount of cups intake. therefore. People with family history of type 1 and 1.5 diabetes should reduced intake of less than 2 cups of coffee per day.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Coffee consumption and the risk of latent autoimmune diabetes in adults--results from a Swedish case-control study by Löfvenborg JE1, Andersson T, Carlsson PO, Dorkhan M, Groop L, Martinell M, Rasouli B, Storm P, Tuomi T, Carlsson S.(PubMed)
(2) Coffee and autoimmunity: More than a mere hot beverage! by Sharif K1, Watad A1, Bragazzi NL2, Adawi M3, Amital H1, Shoenfeld Y4.(PubMed)
(3) Is children's or parents' coffee or tea consumption associated with the risk for type 1 diabetes mellitus in children? Childhood Diabetes in Finland Study Group by Virtanen SM1, Räsänen L, Aro A, Ylönen K, Lounamaa R, Akerblom HK, Tuomilehto J.(PubMed)
(4) Characteristics and Prevalence of Latent Autoimmune Diabetes in Adults (LADA) by Priyanka P. Brahmkshatriya, 1 ,* Anita A. Mehta, 2 Banshi D. Saboo, 3 and Ramesh K. Goyal(PubMed)
(5) Fatty fish consumption and risk of latent autoimmune diabetes in adults by Löfvenborg JE1, Andersson T2, Carlsson PO3, Dorkhan M4, Groop L4, Martinell M5, Tuomi T6, Wolk A1, Carlsson S(PubMed)
(6) Diet diary: You can’t blame family history for type 1.5 diabetes by the Indian Express

* A Tasty Fruit That is Similar to Those of Clonidine, Guanfacine and Metabolite of Methyldopa for Treatment of Hypertension, With No Side Effects

Kyle J. Norton (Master of Nutrition, all right reserved)

Hypertension is medical condition characterized by abnormal high blood pressure in the arteries, persistently.

According to the American Heart Association (AHA) patients with blood pressure that higher than 130 over 80 millimeters of mercury (mmHg) are considered to have hypertension.

According to statistic, approximately, 85 million people in US have high blood pressure.

Untreated hypertension may induce complications of heart attack, stroke, and other health conditions.

Some researchers suggested that unhealthy dietary and lifestyle factors highlights the importance of environmental factors in induction of hypertension onset and progression(4).

However, according to special issue of the Journal of Human Hypertension primarily, in the concerns of dietary, lifestyle and alternative factors in the risk of hypertension and blood pressure control,  focuses on dietary and lifestyle factors, complementary and alternative approaches  may have a strong impact in prevention and treatment of hypertension(4).

Therefore, increased physical activity and diet rich in fruits, vegetables and low-fat dairy products, along with a reduction in saturated and total fat may be the best choice in exerted protective effects on blood pressure(4).

Papaya is a species of Carica Papaya, belongings to the family Caricaceae and native to the tropics of the Americas,. The plant was first cultivated in Mexico and several centuries


Chemical constituents
Alkaloids, Cardenolides, Anthraquinones, Saponins, Tannin, phenol, flavonoid, anthocyanin, Benzyl glucosinolate, benzylisothiocyanate, 5-(Hydroxymethyl)-2-furancarboxaldehyde, 2,3-dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one and 1,3-dihydroxy-2-propanone,.....(a)


Carica papaya, in compared to pucuk ubi (Manihot esculenta), ulam raja (Cosmos caudatus), pegaga (Centella asiatica) and kacang botol (Psophocarpus tetragonolobus), dichloromethane extract of pucuk betik exerts an impressive 59.77% inhibitory activity against key enzymes related to type 2 diabetes and hypertension(1).

The Faculty of Medicine and Health Sciences Universiti Putra Malaysia, after examined the alpha-amylase inhibition assay and at the end of the study suggested that papaya may consist a nutraceutical potential for hyperglycemia and hypertension prevention associated with type 2 diabetes(1).

Injection of crude ethanol extract of 10 microg/mL prepared from the unripened fruit of Carica papaya on using isolated rabbit arterial (aorta, renal and vertebral) strips induced relaxation of vascular muscle tone(2).

In other words, fruit juice of Carica papaya (L.) exhibited anti hypertensive effective through activation of alpha-adrenoceptor(2), similar to those anti hypertension medicine without incuding adverse effects.

Alpha adrenoceptor is protein with function that stimulates vasoconstriction. The receptors found in the skin, the sphincters of gastrointestinal system, kidney (renal artery) and brain(5), play an important role in regulation of blood pressure (BP)(5).

However, intake of papaya and its extract should be taken with care. if you are taking Warfarin. As  according to University of Naples "Federico II", papaya might interact with Warfarin, the most common cardiovascular drug(3).

Please note, due to Alpha 2 receptors that contribute both to control of sympathetic tone and local and regional blood flow, conventional and synthetic version medicine such as clonidine, guanfacine and the active metabolite of methyldopa had copied natural medicine in stimulated Alpha 2 receptors activity in lower BP and in the long-term control of hypertension(5).

Drugs that enhance central alpha 2 activity, such as clonidine, guanfacine and the active metabolite of methyldopa, can significantly lower BP and are effective in the long-term control of hypertension, either alone or in combination with other drugs.

The finding suggested that papaya and its extract may have potential properties in reduced and controlled hypertension through their function in activated Alpha 2 receptors, similar to those of conventional medicine.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


 Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

References
(a) Chemical composition and bioactivity of dried fruits and honey of Ficus carica cultivars Dottato, San Francesco and Citrullara by Loizzo MR1, Bonesi M, Pugliese A, Menichini F, Tundis R.(PubMed)
(1) In vitro inhibitory potential of selected Malaysian plants against key enzymes involved in hyperglycemia and hypertension by Loh SP1, Hadira O.(PubMed)
(2) Blood pressure depression by the fruit juice of Carica papaya (L.) in renal and DOCA-induced hypertension in the rat by Eno AE1, Owo OI, Itam EH, Konya RS.(PubMed)
(3) Cardiovascular pharmacotherapy and herbal medicines: the risk of drug interaction by Izzo AA1, Di Carlo G, Borrelli F, Ernst E.(PubMed)
(4) Dietary and lifestyle factors in hypertension Journal of Human Hypertension by the Journal of Human Hypertension  (2016)
(5) Alpha-adrenergic receptors and blood pressure control by Reid JL(PubMed)