Monday 27 November 2017

Food Therapy: Dried Pea, An Antioxidant Functional Food

Kyle J. Norton


Dried peas may be considered a functional food in enhanced antioxidant activities, some renowned institute studies suggested.

Dried pea is a small but nutritionally mighty member of the legume family, genus Pisum belongings to the family Fabaceae with healthy source of proteins, fibers, vitamins and minerals.

Antioxidant is a natural substances protect our body against cellular damage caused chain reaction of ROS by inhibiting free radical over expression.

In the study to evaluate the The hepatoprotective and antioxidant activities of the hydroalcoholic extract (PE) of pea (Pisum sativum L.) using CCl4-induced oxidative stress and hepatic damage in rats, researchers at the Cairo University revealed that peas demonstrated a significant hepatoprotective and antioxidant activities mostly in n-butanol fraction, a major chemical compound in peas.

After taking into account of other analysis, including Chromatographic fractionation, Dr, said, "pea by-product contained biologically active constituents which can be utilised to obtain high value added products for nutraceutical use".

The hepatoprotective and antioxidant effect of peas one again were attributed to enhanced production of antioxidants such as glutathione (GSH) glutathione-peroxidase (GSH-Px), glutathione-S-transferase (GST) activities in inhibited ROS and its domino effects.

The information may provide additional reason for people with weaken immune system to add additional portion of dried peas into their diet in stimulated antioxidant status in their body.

And, the extra portion of dried peas intake daily will improve immune function in reduced risk diseases caused by bacterial and viral infection and inflammation,....

Other researchers in provide more information of the effects of anti-oxidant and anti-inflammatory properties of peptides from yellow field pea proteins (Pisum sativum L.) through LPS/IFN-γ-activated RAW 264.7 NO⁻ macrophages. researchers at the University of Ottawa, showed that
1. Pea protein hydrolysate, after a 12 h pre-treatment, inhibited NO production by activated macrophages up to 20%.
2. The tested chemical compound also demonstrated a strong inhibition of secretion of pro-inflammatory cytokines, TNF-α- and IL-6, up to 35 and 80%, respectively.
3. Oral administration of PPH in mice enhanced the white blood cell activity in stimulated the gut mucosa immune response.

The findings information showed that the powerful antioxidants properties of pea protein hydrolysate, exerts a significant effect in reduced the expression of pro inflammatory cytokins in regulated immune response.

Dr. Ndiaye F, after taking into account of other con founders said, "Enzymatic protein degradation confers anti-oxidant, anti-inflammatory and immunomodulating potentials to pea proteins, and the resulted peptides could be used as an alternative therapy for the prevention of inflammatory-related diseases".

Furthermore, in the investigated the antioxidant of the broad bean and pea by-products as sources of fiber-rich ingredients, researchers at the after differentiation of v the main monomers such as uronic acids, glucose, arabinose and galactose in broad bean pods, researcher postulated that the most antioxidant activities also are result of extractable polyphenols found in road bean and pea by-products as sources of fibre-rich.

Taking together, dried peas may be used as a functional food in increased antioxidant activity of people with weaken immunity and provided an additional source for treatment of auto immune and inflammatory diseases.



Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Bioassay-guided fractionation of a hepatoprotective and antioxidant extract of peaby-product by Seida AA1, El Tanbouly ND, Islam WT, Eid HH, El Maraghy SA, El Senousy AS.(PubMed)
(2) Anti-oxidant, anti-inflammatory and immunomodulating properties of an enzymatic protein hydrolysate from yellow field pea seeds by Ndiaye F1, Vuong T, Duarte J, Aluko RE, Matar C.(PubMed)
(3) Broad bean and pea by-products as sources of fibre-rich ingredients: potential antioxidant activity measured in vitro by Mateos-Aparicio I1, Redondo-Cuenca A, Villanueva-Suárez MJ.(PubMed)


Alternative Therapy: Yoga in Improvement of Energy Expression

Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)


Yoga may have strong and profound effect in improved energy expression, some scientists suggested.

Yoga, the ancient practical  technique for harmonized external and internal body well beings, through breath control, meditation, bodily movement and gesture..... has been best known for people in Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

In the study to investigate study the effects of yoga poses on subjective sense of energy and self-esteem. in compared to the effects of 'power poses, after taking into account of other confounders, researcher found that yoga group participating meditation score a significantly increased subjective sense of energy in compared to control.

Further analysis, the study also suggested that yoga posts with performing open, expansive body postures may be driven by processes other than the poses' in association with interpersonal power and dominance.

Interestingly, Dr. Golec de Zavala A, the lead author said, " positive effects of yoga practice can occur after performing yoga poses for only 2 min".

Other researchers in the evaluation of the feasibility, acceptability, and patient-reported effectiveness of a clinical yoga program at a Veterans Affairs Medical Center and assessed whether these outcomes differed between those participating in-person and those participating via telehealth based on 64 Veterans completed the survey researchers concluded that more than 80% of veterans showed an improvement of energy levels after participating yoga class.

Furthermore, the returned survey also indicated that yoga participated demonstrated a overall improvement, or improvement in any of 16 specific health problems.


Other study in comparison of the energy expenditure during acute bouts of vinyasa yoga and 2 walking protocols of participants (20 males, 18 females) performed 60-minute sessions of vinyasa yoga (YOGA), treadmill walking at a self-selected brisk pace (SELF), and treadmill walking at a pace that matched the heart rate of the YOGA session (HR-Match) suggested that
Energy expenditure was significantly lower in YOGA compared with HR-Match (difference = 79.5 ± 44.3 kcal; P < .001) and SELF (difference = 51.7 ± 62.6 kcal; P < .001), but not in SELF compared with HR-Match (difference = 27.8 ± 72.6 kcal; P = .054). A similar pattern was observed for metabolic equivalents (HR-Match = 4.7 ± 0.8, SELF = 4.4 ± 0.7, YOGA = 3.6 ± 0.6; P < .001). Analyses using only the initial 45 minutes from each of the sessions, which excluded the restorative component of YOGA, showed energy expenditure was significantly lower in YOGA compared with HR-Match (difference = 68.0 ± 40.1 kcal; P < .001) but not compared with SELF (difference = 15.1 ± 48.7 kcal.

The reduced expenditure of energy in yoga participation may be another indication of yoga participants oashowed significantly energetic expression after yoga class.

Physically, yoga certain postures were also found to improved digestive system  in absorption of nutrients as well as  blood circulation in transport them to the body tissues and organs, thus increasing energy in 2 ways
1. By improving digestive problems such as indigestion, cramping, bloating, constipation.
2. For healthy people, yoga enhanced energy balance, through regulating gut peptides in expression of autocrine signalling

Psychologically, yoga breathing and mediation promoted calmness and relaxation of central nervous system have strong implications in reduced psychic symptoms such as anxiety, depression, stress...improving sleep pattern, particularly in insomnia.

Truly, people with a high level of psychological distress caused psychic problems are often difficult falling and staying asleep and have a tendency to dozing off early and waking up feeling exhausted and decreased energy levels.

Taking altogether, yoga exercise may be considered as primary therapy in improving daily energy  levels for people encountering a hectic life.with full of incessant or frantic activity. 

However, The over all information may only serve as preliminary evidences for the effectiveness of a clinical yoga program before supporting the use of yoga in healthcare settings, specially in energy enhancing.


For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN


Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Yoga Poses Increase Subjective Energy and State Self-Esteem in Comparison to 'Power Poses' by Golec de Zavala A1,2,3, Lantos D1, Bowden D1.(PubMed)
(2) Results from a clinical yoga program for veterans: yoga via telehealth provides comparable satisfaction and health improvements to in-person yoga by Schulz-Heik RJ1, Meyer H2,3, Mahoney L2, Stanton MV2,4, Cho RH2, Moore-Downing DP2, Avery TJ2,3,4, Lazzeroni LC4, Varni JM2, Collery LM2, Bayley PJ2,4.(PubMed)
(3) Energy Expenditure in Vinyasa Yoga Versus Walking by Sherman SA, Rogers RJ, Davis KK, Minster RL, Creasy SA, Mullarkey NC, O'Dell M, Donahue P, Jakicic JM.(PubMed)

Sunday 26 November 2017

Food Therapy: Dried Pea and Bean Fibers in Attenuated Risk and Treatment of Metabolic Syndrome

Kyle J. Norton


Intake of dried peas fiber daily and regularly may reduce risk of metabolic syndrome, some institute studies suggested.

Metabolic syndrome is a biochemical and physiological factors associated with risk of cardiovascular disease and type 2 diabetes.
Dried pea is a small but nutritionally mighty member of the legume family, genus Pisum belongings to the family Fabaceae with healthy source of proteins, fibers, vitamins and minerals.

In the study to investigate the effects of frequent consumption (five cups/week over 8 weeks) of pulses (yellow peas, chickpeas, navy beans and lentils), compared with counselling to reduce energy intake by 2093 kJ/d (500 kcal/d), on risk factors of the MetSyn of in 2 groups (nineteen and twenty-one subjects, respectively) of overweight or obese (mean BMI 32·8 kg/m2) adults, researchers after adjusting to many con founders after 8 weeks of experiment suggested that
1. Pulse group expressed a HDL and C-peptide increased by 4·5 and 12·3 %, respectively in compared to decreased by 0·8 and 7·6 %, respectively, in the energy-restricted group.
2. Insulin AUC decreased in both females and males on the energy-restricted diet by 24·2 and 4·8 %, respectively and on the pulse diet it decreased by 13·9 % in females and 27·3 % in males respectively.

Based on the result interpretation, Dr. Mollard RC, the lead author said," frequent consumption of pulses in an ad libitum diet reduced risk factors of the MetSyn".

C-peptide is a substance produced by the beta cells in the pancreas with function to connects insulin's A-chain to its B-chain in the insulin molecule.

Insulin AUC is the area under the curve in a 2 dimension coordinate used to measure the insulin concentration in blood insulin vs. time.

Unfortunately, the method of used to calculate AUC may affect the interpretation of whether or not an intervention was effective, according to some researchers.

In support of the above study, the Fahan University of Medical Sciences conducted a cross-sectional study of 425 subjects 35 to 55 y of age, using a food-frequency questionnaire. including in the report of blood pressure, waist circumference, glucose, triacylglycerols, and high-density lipoprotein cholesterol to measure risk of metabolic syndrome defined based on Adult Treatment Panel III guidelines, after examining the returned questionnaire, researchers found that daily intake of these groups of population can be classified into 5 pattern, namely,
1. A western pattern (high in sweets, butter, soda, mayonnaise, sugar, cookies, tail of a lamb, hydrogenated fat, and eggs)
2. A prudent pattern (high in fish, peas, honey, nuts, juice, dry fruits, vegetable oil, liver and organic meat, and coconuts and low in hydrogenated fat and non-leafy vegetables)
3. A vegetarian pattern (high in potatoes, legumes, fruits rich in vitamin C, rice, green leafy vegetables, and fruits rich in vitamin A),
4. A high-fat dairy pattern (high in high-fat yogurt and high-fat milk and low in low-fat yogurt, peas, and bread),
5. A chicken and plant pattern (high in chicken, fruits rich in vitamin A, green leafy vegetables, and mayonnaise and low in beef, liver, and organic meat)

And in compare to all 5 groups
1. The western pattern was associated with greater odds of having increased triacylglycerol and blood pressure
2. The The prudent pattern was positively associated with a prevalence of low high-density lipoprotein cholesterol levels
3. The vegetarian dietary pattern was inversely associated with a risk of an abnormal fasting blood glucose level

Adult Treatment Panel III guideline is used as classification of LDL, Total, and HDL Cholesterol (mg/dL).

Dr. Amini M, the lead authors emphasized, " Major dietary patterns were significantly associated with the risk of metabolic syndrome".

In other word, there is no specific diet pattern can be considered as daily diet in reduced risk of metabolic syndrome. Mix of ingredients of above diet selectively may be necessary for people who are at higher risk of such syndrome

Interestingly, in the study to develop baked and extruded functional foods from Metabolic Syndrome (MS) specific designed ingredient mixes with optimum amino acid makeup using key food ingredients with functional properties such as whole cereals, legumes, skimmed milk powder, along with flaxseeds and fenugreek seeds, researchers after taking into account of other con founders suggested that six ingredient mixes from above of breads and four ingredient mixes each of extruded snack and noodles showed a specifically designed for MS patients who had significantly (p ≤ 0.05) higher lysine, crude protein, ash and fibre and low carbohydrates in compare control whole wheat flour products, hence appropriate for MS patients.

Taking altogether, dried peas and bean fibers may be used conjunction in vegetarian diet to provide a strong impact in ameliorated risk and treatment of metabolic syndrome.



Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Regular consumption of pulses for 8 weeks reduces metabolic syndrome risk factors in overweight and obese adults by Mollard RC1, Luhovyy BL, Panahi S, Nunez M, Hanley A, Anderson GH.(PubMed)
(2) Development of baked and extruded functional foods from metabolic syndromespecific ingredient mix by Miglani N1, Bains K1, Kaur H1.(PubMed)
(3) Relationship between major dietary patterns and metabolic syndrome among individuals with impaired glucose tolerance.
Amini M1, Esmaillzadeh A, Shafaeizadeh S, Behrooz J, Zare M.

Food Therapy: Coffee(3 to 5 Cups/ Day) Has A Maximum Effect in Reduced Risk of Cardiovascular Disease in Healthy Adults



By Kyle J. Norton


Coffee consumers may have one less risk to worry about. A recent study by best known institute suggested that long term and moderate coffee consumption is inversely associated with CVD risk.

Coffee, becoming a popular and social beverage all over the world, particularly in the West, is a drink made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.

Caffeine, a chemical stimulant found abundantly in tea and coffee is a class of methylxanthine having a profound impact in central nervous system (CNS).

Cardiovascular disease is a medical condition characterized by heart attack, chest pain (angina) or stroke caused by narrow blood vessels induced block blood.

In the review of literature existed from the data base involved prospective cohort studies of the relationship between coffee consumption and CVD risk, 36 satisfied the criteria and guidelines included studies, with 1 279 804 participants and 36 352 CVD cases, coffee drinkers have a nonlinearly inverse association to risk of CVD, depending to numbers of cup intake per day.

According to the joint study lead by the Harvard School of Public Health, the relative risk of cardiovascular disease in coffee consumption was .95 in compared with the 0 cup of coffee consumption per day.

Dr. Ding M, the lead author in the review said, "oderate coffee consumption was inversely significantly associated with CVD risk, with the lowest CVD risk at 3 to 5 cups per day, and heavy coffee consumption was not associated with elevated CVD risk".

In fact, long term moderate coffee consumption not only reduced risk of heart disease, but also ameliorated other conditions associated with CV risk factors such as obesity and depression.
However, the affect of caffeine in lipid file may associate to endothelial function in increased CVD risk, depending to how the coffee is prepared.

Obesity is a medical condition of excess body fat accumulated overtime with BMI index over 30. According to statistic, over 68% of US population are either over weight or obese.

According to general belief, obese patients are susceptible to increased risk of various acute and chronic diseases, including  arthritis, stroke, chronic lower back pain, (nonalcoholic steatohepatitis) non-alcoholic fatty liver disease,........

More importantly, epidemiological studies also suggest that risks of mortality in both CV and all-causes are substantially attenuated in regular coffee drinkers.

Furthermore, other researchers insisted that the health benefits of coffee consumption regarding to cardiovascular system risk, mostly depend on its antioxidant compounds involved many factors, such as variety of coffee species, roasting degree, type of brewing method and serving size.

Antioxidant is types of chemical compound inhibited the free radicals to protect the body against oxidative damage cause of cellular dysfunction which has been found to increased risk of metabolic syndrome epidemiologically, a major risk factor of CVD development.

Some searchers concerned that caffeine as a brain stimulant after intake, may stimulate the sympathetic nervous system, inducing rise of blood pressure, release of adrenaline and increased heart beat harder and faster that may cause enormous problem to people with precondition of CVD.
However. for healthy individuals, coffee and coffee caffeine have a reduced prevalence of CVD incidence

Since most of the data on coffee's health effects are based on observational data, risk of high caffeine adverse effects such as anxiety, insomnia, tremulousness, and palpitations have rarely be mentioned, therefore, more randomized, controlled studies are necessary, some researchers suggested.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

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Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Long-term coffee consumption and risk of cardiovascular disease: a systematic review and a dose-response meta-analysis of prospective cohort studies by Ding M1, Bhupathiraju SN, Satija A, van Dam RM, Hu FB.(PubMed)
(2) Effects of habitual coffee consumption on cardiometabolic disease, cardiovascular health, and all-cause mortality by O'Keefe JH1, Bhatti SK, Patil HR, DiNicolantonio JJ, Lucan SC, Lavie CJ.(PubMed)

Saturday 25 November 2017

Alternative Therapy: Yoga in Reduced Symptoms and Treatment of Child Asperger Syndrome

Kyle J. Norton

Yoga my have a strong implication in reduced symptoms and treatment of  Asperger syndrome, some scientists suggested.

Yoga, the ancient practical technique for harmonized external and internal body well being, through breath control, meditation, bodily movement and gesture..... has been well known for people in Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

 Asperger syndrome, is neuro condition characterized by poor social and communication skills, patients may talk a lot, but fail to focus and keep up with the subject and also have a very narrow interest as they may talk about only one single subject for months or years.

Some children with Asperger syndrome may also engage in repetitive behaviour such as flagging hand.

In the study of a 7-year-old boy with Apert and Asperger's syndrome attended 8, 45 min multisensory yoga sessions, twice a week, during 4-week camp conducted by the Texas State University, researchers filed the following result
1. Yoga participated showed a significant improvement in the total score changes from 19 to 7 for disruptive behaviors.
2. The child after yoga class also displayed a changed from showing progression in ability to stay on task of subjects, observed by Sparks Target Behavior Checklist scores
3. Yoga Pose Rating Scale examined by demonstrated the transformation in total scores also improved from 80 = emerging to 115 = consistency in pose performance.

Researchers after taking into account of other confounders indicated that the improvement of behavior and subjects focused may be attributed to the positive development in expressive emotions, social engagement, and decline in looking around attitude.

Furthermore, conversation with child parents also revealed that child has shown a strong improvement of ability to self-regulate stress using lion's breath and super brain.

Dr. Scroggins ML, the lead author said, "These findings indicate an improvement in behaviors that influenced the physical performance, emotional expression, and social interaction after yoga training for this child".

In further differentiation of the effect of yoga in children with brain development disorders, researchers at the joint study lead by the Oregon Health and Science University launched a study to investigate whether yoga mind-body therapies have any implication on symptoms of Social and communication skills and repetitive behavior in children with autism by reviewing literature published on data base of PubMed, PsychInfo, and Scopus, showed that all qualified studies expressed an improvement of mind-body therapies in associated outcomes of behavior, psychological symptoms, and quality of life.

In fact, children with disruptive or inappropriate behaviors probably is a result of psychological effects in induced inappropriate sensory input caused by anxiety, frustration and difficult emotional expression.

Yoga physical postures, according to instructors provide a valuably integrated tool to reduce anxiety and support sensory regulation which may improve emotional and behavioral regulation.

Further more, the physical posture learned from yoga along with breathing can calm and relax the nervous system in controlled impulsive behaviors and motion.  

Some yoga instructors also suggested that the calming and relaxing effect by yoga  exercise in physical posture along with breathing strategy may also improve concentration though calming the mind of the children with Asperger syndrome and getting rid of distracting thoughts and, thus improving concentration

Additionally, long term yoga regular practice also reduced stress, anxiety and tension, thus promoting relaxation and calmness which have been found to have strong impact in concentration, reduced impulsive and inappropriate behaviors and improved emotional expression.

In a distant further, the strong implication of regular yoga practice also improved the brain performance by keeping the mind active and sharp, particularly in resolved daily problems.

Although all studies were conducted in a small same size and uncontrollable design, they would benefit from larger randomized controlled trials.

The findings indicated that yoga taught by experts may be considered as secondary therapeutic treatment used conjunction with standard therapy in reduced system expression and treatment of Asperger syndrome.



For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN


Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Effects of multisensory yoga on behavior in a male child with Apert and Asperger syndrome by Scroggins ML1, Litchke LG2, Liu T2.(PubMed)
(2) Autism and Mind-Body Therapies: A Systematic Review by Hourston S1,2, Atchley R1.(PubMed)
(3) Effects of multisensory yoga on behavior in a male child with Apert and Asperger syndrome by Michaela L Scroggins, Lyn G Litchke,1 and Ting Liu1(PMC)

Food Therapy: Coffee and Coffee Caffeine, in Reduced Risk of Basal Cell Skin Cancer


By Kyle J. Norton


Coffee and coffee caffeine consumption regularly is associated to ameliorated risk of basal cell carcinoma of the skin, the Queensland Institute of Medical Research study suggested.

Coffee, becoming a popular and social beverage all over the world, particularly in the West, is a drink made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.

Basal cell cancer (BCC) is the most common type of skin cancer characterized by abnormal growth of the cells in the lowest layer of the epidermis.

The cancer rarely spread and kill but can cause significant destruction and disfigurement to the affected skin area and accounted for more than 90% of all skin cancer in the U.S.

In the study among 1,325 randomly selected adult residents of a subtropical Australian community collected in 1992, 1994, and 1996, returned food frequency questionnaires from participants showed a significantly lower relative risk in people with with prior skin cancers by 25% with daily consumption of four cups of regular coffee.

Caffeine, a chemical stimulant found abundantly in caffeinated products, including tea and coffee is a class of methylxanthine having a profound impact in central nervous system (CNS).

For people without previous history of skin disease, consumption of neither caffeinated nor decaffeinated coffee regardless of amount intake expressed no risk of basal cell carcinoma.

Dr. Miura K, the lead author said, " Among people with prior skin cancers, a relatively high caffeine intake may help prevent subsequent BCC development. However, caffeine intake appears not to influence the risk of SCC."

Squamous cell cancer(SCC),is another type of skin cancer arises from the uncontrolled multiplication of transformed malignant cells in the middle layer of the epidermis. In the later stage, the disease can spread to organs and tissues distant away from the original site.

Additionally, in the evaluation of the effects of tea, coffee, and caffeine related to early-onset BCC from data of 767 non-Hispanic Whites under age 40 in Connecticut. BCC cases (n=377) identified through Yale's Dermatopathology database and controls (n=390) of individuals in the same database, participants interview revealed combined regular consumption of caffeinated coffee plus hot tea expressed a strong inverse association of early-onset BCC.

Further analysis and after taking into account of other con-founders, risk of BCC was reduced by as much as 43% in this group in compared to non drinking group.

Researchers at the study also indicated that the efficacy in reduced risk of basal cell carcinoma of the skin from these 2 beverages may be attributed to chemical component of caffeine in expression of antioxidant and immunomodulating activities.

Promisingly. in the support of caffeine administration in prevented squamous cells skin cancer development, the Nurses' Health Study and the Health Professionals Follow-up Study, postulated the following results.
1. Caffeine intake from all dietary sources was inversely associated with BCC risk even people who only consumed less than 1 cup of caffeinated coffee per month.
2. Women who consumed more than 3 cups/d had the relative odd risk ratio of 0.79, in compared to 0.90 in men with the same cups intake.
3. Decaffeinated coffee consumption showed no association in decreased BCC risk.

The finding evidences expressed that coffee and coffee caffeine consumption have a significant effect in reduced risk of basal cell carcinoma of the skin, particularly in people with previous skin cancer.

But some researchers had raised questions that the efficacy of coffee in reduced risk of BCC may be attributed to other components in the coffee as many variables and co-factors have not been taken into the studies.


Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Author biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Caffeine intake and risk of basal cell and squamous cell carcinomas of the skin in an 11-year prospective study by Miura K1, Hughes MC, Green AC, van der Pols JC.(PubMed)
(2) Tea, coffee, and caffeine and early-onset basal cell carcinoma in a case-control study by Ferrucci LM1, Cartmel B, Molinaro AM, Leffell DJ, Bale AE, Mayne ST.(PubMed)
(3) Increased caffeine intake is associated with reduced risk of basal cell carcinoma of the skin by Song F1, Qureshi AA, Han J.(PubMed)

Friday 24 November 2017

Food Therapy: Common (Dried) Peas In Stimulated Immunomodulating Expression

Kyle J. Norton


Intake of common (dried) peas daily and regularly may have a potential effect in enhanced immunomodulating activity, scientists at some renowned institute studies suggested.

Dried pea is a small but nutritionally mighty member of the legume family, genus Pisum belongings to the family Fabaceae with healthy source of proteins, fibers, vitamins and minerals.

Immunomodulation is an action with profound and positive effect in regulated immune response and function through activation of antibody formation or the inhibition of white blood cell activity.

In the evaluation of 173 LAB strains, including the strain NTM048 isolated from green peas having ability to induce IgA production using murine Peyer's patch cells, researchers at the Ishikawa Prefectural University, after taking account of other con founders suggested that
1. Strain NTM048 isolated from green peas demonstrated a higher immunomodulating activiy in compared to other straits.
2. The green pea strait also is well tolerated in gastrointestinal digestion and produce large amounts of exopolysaccharides, a high-molecular-weight polymers which has been used in conventional medicine for prospect of anticoagulant, antithrombotic, immunomodulation, anticancer and as bioflocculants.
3. Application of the strait also induced a significant increase in the faecal IgA content and plasma IgA levels in response to immunogen of BALB/cA mice

Further analysis of the function of strait isolated from green pea, researchers emphasized that the strait have a significant impact in stimulated immunomodulating activities through regulating the transforming growth factor-β in secretion of inflammatory cytokins which play an important role in control of cell growth, cell proliferation, cell differentiation and apoptosis.

The action of the strait in activation of immunomodurating activity was also attributed by stimulating Peyer's patch cells which are aggregated in lymphoid nodules, formed an important part of the immune system.

The information findings prompted Dr. Matsuzaki C, the lead author to suggested, "Strain NTM048 stimulates Peyer's patch cells to induce intestinal and systemic immune response, revealing the potential of NTM048 as a probiotic for enhancing the mucosal barrier function".

The collective information of NTM048 as a probiotic may be helpful to reduce symptoms and treatments of people with digestive disorder by including portions of green peas or dried peas in their daily diet.

Additionally, but in other field of study, researchers at the University of Ottawa launched an investigation of immunomodulating activity of enzymatic protein hydrolysates of yellow pea using in a murine model indicated that
1. Oral administration of Pea protein hydrolysate, after a 12 h pre-treatment, showed a significant inhibition of free radical NO production by activating increased mobile white blood cell by 20%.

The reduction of ROS may be a result of over expression of antioxidant production in stimulated immunomdulqating effect to protect against localized tissue and injure against infection and inflammation caused by foreign pathogens.

2. The injection also showed a strongly inhibited secretion of pro-inflammatory cytokines, TNF-α- and IL-6,in a range of 35 and 80%, respectively.

TNF-α, Tumor necrosis factor is a protein with function in initiated response in the acute phrase of inflammation

IL-6 (Interleukin 6) secreted by immune system to stimulate immune response, is an interleukin with duo functions in promoted either pro and anti inflammatory cytokins or mytokins respectively.
The inhibition of pro inflammatory substance of the pea protein may have a potential effect in reduced symptoms and complications such as reddened, swollen, hot, and often painful in the location of injury or infection.

3. The protein also stimulated the gut mucosa immune response.
Gut mucosa immune response against harmful intestinal organisms have a strong impact in reduced risk of digestive disorder, through regulating the function of lymphoid tissue located at the mucosa.

According to the article of mucosal immunology, "the mucosal immune system provides protection against pathogens but maintains a tolerance towards non-harmful commensal microbes and benign environmental substances".

4. The immunomodutating effect also found in increased number of IgA+ cells in the the small intestine lamina propria accompanied by an increase in the number of IL-4+, IL-10+ and IFN-γ+ cells.

In this case, the immunomodating effect through expression of production of  IgA+ cells in
protected the intestine lamina propria(based membrance) from pathogens, toxins and food antigens the basement remembrance of the intestine by increased the numbers of interleukin IL-4+, IL-10+ in inhibited production of pro inflammatory cytokins as well as increased function of IFN-γ+  cells in stimulated innate and adaptive immunity against viral, some bacterial and protozoal infections.

Further differentiation also suggested that the enhanced IL-6 secretion of small intestine epithelial cells (IEC) by the Pea protein hydrolysate in stimulation IgA-secretion, probably associated to numbers of mechanism, particularly in TLR2 and TLR4 function in pathogen recognition and activation of innate immunity.

Taking altogether, green peas or common peas may be considered as therapeutic treatment in enhanced mmunomodulating activity, particularly to aging adults and people with history of weakened immunity.


Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Immunomodulating activity of exopolysaccharide-producing Leuconostoc mesenteroides strain NTM048 from green peas by Matsuzaki C1, Kamishima K, Matsumoto K, Koga H, Katayama T, Yamamoto K, Hisa K.(PubMed)
(2)Anti-oxidant, anti-inflammatory and immunomodulating properties of an enzymatic protein hydrolysate from yellow field pea seeds by Ndiaye F1, Vuong T, Duarte J, Aluko RE, Matar C.(PubMed)
(3) Mucosal immunology by Nature.com