Food Therapy: Coffee(3 to 5 Cups/ Day) Has A Maximum Effect in Reduced Risk of Cardiovascular Disease in Healthy Adults

By Kyle J. Norton


Coffee consumers may have one less risk to worry about. A recent study by best known institute suggested that long term and moderate coffee consumption is inversely associated with CVD risk.

Coffee, becoming a popular and social beverage all over the world, particularly in the West, is a drink made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.

Caffeine, a chemical stimulant found abundantly in tea and coffee is a class of methylxanthine having a profound impact in central nervous system (CNS).

Cardiovascular disease is a medical condition characterized by heart attack, chest pain (angina) or stroke caused by narrow blood vessels induced block blood.

In the review of literature existed from the data base involved prospective cohort studies of the relationship between coffee consumption and CVD risk, 36 satisfied the criteria and guidelines included studies, with 1 279 804 participants and 36 352 CVD cases, coffee drinkers have a nonlinearly inverse association to risk of CVD, depending to numbers of cup intake per day.

According to the joint study lead by the Harvard School of Public Health, the relative risk of cardiovascular disease in coffee consumption was .95 in compared with the 0 cup of coffee consumption per day.

Dr. Ding M, the lead author in the review said, "oderate coffee consumption was inversely significantly associated with CVD risk, with the lowest CVD risk at 3 to 5 cups per day, and heavy coffee consumption was not associated with elevated CVD risk".

In fact, long term moderate coffee consumption not only reduced risk of heart disease, but also ameliorated other conditions associated with CV risk factors such as obesity and depression.
However, the affect of caffeine in lipid file may associate to endothelial function in increased CVD risk, depending to how the coffee is prepared.

Obesity is a medical condition of excess body fat accumulated overtime with BMI index over 30. According to statistic, over 68% of US population are either over weight or obese.

According to general belief, obese patients are susceptible to increased risk of various acute and chronic diseases, including  arthritis, stroke, chronic lower back pain, (nonalcoholic steatohepatitis) non-alcoholic fatty liver disease,........

More importantly, epidemiological studies also suggest that risks of mortality in both CV and all-causes are substantially attenuated in regular coffee drinkers.

Furthermore, other researchers insisted that the health benefits of coffee consumption regarding to cardiovascular system risk, mostly depend on its antioxidant compounds involved many factors, such as variety of coffee species, roasting degree, type of brewing method and serving size.

Antioxidant is types of chemical compound inhibited the free radicals to protect the body against oxidative damage cause of cellular dysfunction which has been found to increased risk of metabolic syndrome epidemiologically, a major risk factor of CVD development.

Some searchers concerned that caffeine as a brain stimulant after intake, may stimulate the sympathetic nervous system, inducing rise of blood pressure, release of adrenaline and increased heart beat harder and faster that may cause enormous problem to people with precondition of CVD.
However. for healthy individuals, coffee and coffee caffeine have a reduced prevalence of CVD incidence

Since most of the data on coffee's health effects are based on observational data, risk of high caffeine adverse effects such as anxiety, insomnia, tremulousness, and palpitations have rarely be mentioned, therefore, more randomized, controlled studies are necessary, some researchers suggested.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

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FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Long-term coffee consumption and risk of cardiovascular disease: a systematic review and a dose-response meta-analysis of prospective cohort studies by Ding M1, Bhupathiraju SN, Satija A, van Dam RM, Hu FB.(PubMed)
(2) Effects of habitual coffee consumption on cardiometabolic disease, cardiovascular health, and all-cause mortality by O'Keefe JH1, Bhatti SK, Patil HR, DiNicolantonio JJ, Lucan SC, Lavie CJ.(PubMed)

Alternative Therapy: Yoga in Reduced Symptoms and Treatment of Child Asperger Syndrome

Kyle J. Norton

Yoga my have a strong implication in reduced symptoms and treatment of  Asperger syndrome, some scientists suggested.

Yoga, the ancient practical technique for harmonized external and internal body well being, through breath control, meditation, bodily movement and gesture..... has been well known for people in Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

 Asperger syndrome, is neuro condition characterized by poor social and communication skills, patients may talk a lot, but fail to focus and keep up with the subject and also have a very narrow interest as they may talk about only one single subject for months or years.

Some children with Asperger syndrome may also engage in repetitive behaviour such as flagging hand.

In the study of a 7-year-old boy with Apert and Asperger's syndrome attended 8, 45 min multisensory yoga sessions, twice a week, during 4-week camp conducted by the Texas State University, researchers filed the following result

1. Yoga participated showed a significant improvement in the total score changes from 19 to 7 for disruptive behaviors.

2. The child after yoga class also displayed a changed from showing progression in ability to stay on task of subjects, observed by Sparks Target Behavior Checklist scores
3. Yoga Pose Rating Scale examined by demonstrated the transformation in total scores also improved from 80 = emerging to 115 = consistency in pose performance.

Researchers after taking into account of other confounders indicated that the improvement of behavior and subjects focused may be attributed to the positive development in expressive emotions, social engagement, and decline in looking around attitude.

Furthermore, conversation with child parents also revealed that child has shown a strong improvement of ability to self-regulate stress using lion's breath and super brain.

Dr. Scroggins ML, the lead author said, "These findings indicate an improvement in behaviors that influenced the physical performance, emotional expression, and social interaction after yoga training for this child".

In further differentiation of the effect of yoga in children with brain development disorders, researchers at the joint study lead by the Oregon Health and Science University launched a study to investigate whether yoga mind-body therapies have any implication on symptoms of Social and communication skills and repetitive behavior in children with autism by reviewing literature published on data base of PubMed, PsychInfo, and Scopus, showed that all qualified studies expressed an improvement of mind-body therapies in associated outcomes of behavior, psychological symptoms, and quality of life.

In fact, children with disruptive or inappropriate behaviors probably is a result of psychological effects in induced inappropriate sensory input caused by anxiety, frustration and difficult emotional expression.

Yoga physical postures, according to instructors provide a valuably integrated tool to reduce anxiety and support sensory regulation which may improve emotional and behavioral regulation.

Further more, the physical posture learned from yoga along with breathing can calm and relax the nervous system in controlled impulsive behaviors and motion.  

Some yoga instructors also suggested that the calming and relaxing effect by yoga  exercise in physical posture along with breathing strategy may also improve concentration though calming the mind of the children with Asperger syndrome and getting rid of distracting thoughts and, thus improving concentration

Additionally, long term yoga regular practice also reduced stress, anxiety and tension, thus promoting relaxation and calmness which have been found to have strong impact in concentration, reduced impulsive and inappropriate behaviors and improved emotional expression.

In a distant further, the strong implication of regular yoga practice also improved the brain performance by keeping the mind active and sharp, particularly in resolved daily problems.

Although all studies were conducted in a small same size and uncontrollable design, they would benefit from larger randomized controlled trials.

The findings indicated that yoga taught by experts may be considered as secondary therapeutic treatment used conjunction with standard therapy in reduced system expression and treatment of Asperger syndrome.

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Techniquue That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half  

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Effects of multisensory yoga on behavior in a male child with Apert and Asperger syndrome by Scroggins ML1, Litchke LG2, Liu T2.(PubMed)
(2) Autism and Mind-Body Therapies: A Systematic Review by Hourston S1,2, Atchley R1.(PubMed)
(3) Effects of multisensory yoga on behavior in a male child with Apert and Asperger syndrome by Michaela L Scroggins, Lyn G Litchke,1 and Ting Liu1(PMC)

Food Therapy: Coffee and Coffee Caffeine, in Reduced Risk of Basal Cell Skin Cancer

By Kyle J. Norton


Coffee and coffee caffeine consumption regularly is associated to ameliorated risk of basal cell carcinoma of the skin, the Queensland Institute of Medical Research study suggested.

Coffee, becoming a popular and social beverage all over the world, particularly in the West, is a drink made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.

Basal cell cancer (BCC) is the most common type of skin cancer characterized by abnormal growth of the cells in the lowest layer of the epidermis.

The cancer rarely spread and kill but can cause significant destruction and disfigurement to the affected skin area and accounted for more than 90% of all skin cancer in the U.S.

In the study among 1,325 randomly selected adult residents of a subtropical Australian community collected in 1992, 1994, and 1996, returned food frequency questionnaires from participants showed a significantly lower relative risk in people with with prior skin cancers by 25% with daily consumption of four cups of regular coffee.

Caffeine, a chemical stimulant found abundantly in caffeinated products, including tea and coffee is a class of methylxanthine having a profound impact in central nervous system (CNS).

For people without previous history of skin disease, consumption of neither caffeinated nor decaffeinated coffee regardless of amount intake expressed no risk of basal cell carcinoma.

Dr. Miura K, the lead author said, " Among people with prior skin cancers, a relatively high caffeine intake may help prevent subsequent BCC development. However, caffeine intake appears not to influence the risk of SCC."

Squamous cell cancer(SCC),is another type of skin cancer arises from the uncontrolled multiplication of transformed malignant cells in the middle layer of the epidermis. In the later stage, the disease can spread to organs and tissues distant away from the original site.

Additionally, in the evaluation of the effects of tea, coffee, and caffeine related to early-onset BCC from data of 767 non-Hispanic Whites under age 40 in Connecticut. BCC cases (n=377) identified through Yale's Dermatopathology database and controls (n=390) of individuals in the same database, participants interview revealed combined regular consumption of caffeinated coffee plus hot tea expressed a strong inverse association of early-onset BCC.

Further analysis and after taking into account of other con-founders, risk of BCC was reduced by as much as 43% in this group in compared to non drinking group.

Researchers at the study also indicated that the efficacy in reduced risk of basal cell carcinoma of the skin from these 2 beverages may be attributed to chemical component of caffeine in expression of antioxidant and immunomodulating activities.

Promisingly. in the support of caffeine administration in prevented squamous cells skin cancer development, the Nurses' Health Study and the Health Professionals Follow-up Study, postulated the following results.
1. Caffeine intake from all dietary sources was inversely associated with BCC risk even people who only consumed less than 1 cup of caffeinated coffee per month.
2. Women who consumed more than 3 cups/d had the relative odd risk ratio of 0.79, in compared to 0.90 in men with the same cups intake.
3. Decaffeinated coffee consumption showed no association in decreased BCC risk.

The finding evidences expressed that coffee and coffee caffeine consumption have a significant effect in reduced risk of basal cell carcinoma of the skin, particularly in people with previous skin cancer.

But some researchers had raised questions that the efficacy of coffee in reduced risk of BCC may be attributed to other components in the coffee as many variables and co-factors have not been taken into the studies.


Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Author biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Caffeine intake and risk of basal cell and squamous cell carcinomas of the skin in an 11-year prospective study by Miura K1, Hughes MC, Green AC, van der Pols JC.(PubMed)
(2) Tea, coffee, and caffeine and early-onset basal cell carcinoma in a case-control study by Ferrucci LM1, Cartmel B, Molinaro AM, Leffell DJ, Bale AE, Mayne ST.(PubMed)
(3) Increased caffeine intake is associated with reduced risk of basal cell carcinoma of the skin by Song F1, Qureshi AA, Han J.(PubMed)

Food Therapy: Common (Dried) Peas In Stimulated Immunomodulating Expression

Kyle J. Norton


Intake of common (dried) peas daily and regularly may have a potential effect in enhanced immunomodulating activity, scientists at some renowned institute studies suggested.

Dried pea is a small but nutritionally mighty member of the legume family, genus Pisum belongings to the family Fabaceae with healthy source of proteins, fibers, vitamins and minerals.

Immunomodulation is an action with profound and positive effect in regulated immune response and function through activation of antibody formation or the inhibition of white blood cell activity.

In the evaluation of 173 LAB strains, including the strain NTM048 isolated from green peas having ability to induce IgA production using murine Peyer's patch cells, researchers at the Ishikawa Prefectural University, after taking account of other con founders suggested that

1. Strain NTM048 isolated from green peas demonstrated a higher immunomodulating activiy in compared to other straits.

2. The green pea strait also is well tolerated in gastrointestinal digestion and produce large amounts of exopolysaccharides, a high-molecular-weight polymers which has been used in conventional medicine for prospect of anticoagulant, antithrombotic, immunomodulation, anticancer and as bioflocculants.

3. Application of the strait also induced a significant increase in the faecal IgA content and plasma IgA levels in response to immunogen of BALB/cA mice

Further analysis of the function of strait isolated from green pea, researchers emphasized that the strait have a significant impact in stimulated immunomodulating activities through regulating the transforming growth factor-β in secretion of inflammatory cytokins which play an important role in control of cell growth, cell proliferation, cell differentiation and apoptosis.

The action of the strait in activation of immunomodurating activity was also attributed by stimulating Peyer's patch cells which are aggregated in lymphoid nodules, formed an important part of the immune system.

The information findings prompted Dr. Matsuzaki C, the lead author to suggested, "Strain NTM048 stimulates Peyer's patch cells to induce intestinal and systemic immune response, revealing the potential of NTM048 as a probiotic for enhancing the mucosal barrier function".

The collective information of NTM048 as a probiotic may be helpful to reduce symptoms and treatments of people with digestive disorder by including portions of green peas or dried peas in their daily diet.

Additionally, but in other field of study, researchers at the University of Ottawa launched an investigation of immunomodulating activity of enzymatic protein hydrolysates of yellow pea using in a murine model indicated that

1. Oral administration of Pea protein hydrolysate, after a 12 h pre-treatment, showed a significant inhibition of free radical NO production by activating increased mobile white blood cell by 20%.

The reduction of ROS may be a result of over expression of antioxidant production in stimulated immunomdulqating effect to protect against localized tissue and injure against infection and inflammation caused by foreign pathogens.

2. The injection also showed a strongly inhibited secretion of pro-inflammatory cytokines, TNF-α- and IL-6,in a range of 35 and 80%, respectively.

TNF-α, Tumor necrosis factor is a protein with function in initiated response in the acute phrase of inflammation

IL-6 (Interleukin 6) secreted by immune system to stimulate immune response, is an interleukin with duo functions in promoted either pro and anti inflammatory cytokins or mytokins respectively.
The inhibition of pro inflammatory substance of the pea protein may have a potential effect in reduced symptoms and complications such as reddened, swollen, hot, and often painful in the location of injury or infection.

3. The protein also stimulated the gut mucosa immune response.

Gut mucosa immune response against harmful intestinal organisms have a strong impact in reduced risk of digestive disorder, through regulating the function of lymphoid tissue located at the mucosa.

According to the article of mucosal immunology, "the mucosal immune system provides protection against pathogens but maintains a tolerance towards non-harmful commensal microbes and benign environmental substances".

4. The immunomodutating effect also found in increased number of IgA+ cells in the the small intestine lamina propria accompanied by an increase in the number of IL-4+, IL-10+ and IFN-γ+ cells.

In this case, the immunomodating effect through expression of production of  IgA+ cells in
protected the intestine lamina propria(based membrance) from pathogens, toxins and food antigens the basement remembrance of the intestine by increased the numbers of interleukin IL-4+, IL-10+ in inhibited production of pro inflammatory cytokins as well as increased function of IFN-γ+  cells in stimulated innate and adaptive immunity against viral, some bacterial and protozoal infections.

Further differentiation also suggested that the enhanced IL-6 secretion of small intestine epithelial cells (IEC) by the Pea protein hydrolysate in stimulation IgA-secretion, probably associated to numbers of mechanism, particularly in TLR2 and TLR4 function in pathogen recognition and activation of innate immunity.

Taking altogether, green peas or common peas may be considered as therapeutic treatment in enhanced mmunomodulating activity, particularly to aging adults and people with history of weakened immunity.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Immunomodulating activity of exopolysaccharide-producing Leuconostoc mesenteroides strain NTM048 from green peas by Matsuzaki C1, Kamishima K, Matsumoto K, Koga H, Katayama T, Yamamoto K, Hisa K.(PubMed)
(2)Anti-oxidant, anti-inflammatory and immunomodulating properties of an enzymatic protein hydrolysate from yellow field pea seeds by Ndiaye F1, Vuong T, Duarte J, Aluko RE, Matar C.(PubMed)
(3) Mucosal immunology by Nature.com

Food Therapy: Dried Peas, The Best in Prediction, Prevention and Treatment of Liver Diseases

Kyle J. Norton


Intake of dried peas daily and regularly may associate to reduce risk of liver diseases, scientists at some respectable institute studies suggested.

Dried pea is a small but nutritionally mighty member of the legume family, genus Pisum belongings to the family Fabaceae with healthy source of proteins, fibers, vitamins and minerals.

Liver diseases are set of medical condition, ranging from Cirrhosis, or scarring of the liver. Inflammation (hepatitis) from infectious (hepatitis B, hepatitis C) to benign and malignant tumors.

In a hydroalcoholic extract (PE) of pea (Pisum sativum L.) by-product was investigate for its hepatoprotective against CCl4-induced oxidative stress and hepatic damage in rats, researchers at the Cairo University after taking account of existed con founders, found that
1. The by product displayed a significant effect in reduced ROS expression in induction of liver damamge through enhance antioxidant activity.
2. N-butanol fraction isolated from hydroalcoholic extract (PE) demonstrated stronger liver protective effect in compare to other petrochemicals.

The findings demonstrated that  hydroalcoholic extract (PE) of pea by-product can be utilized to obtain high value added products for therapeutic use in ameliorated risk and treatment liver diseases.

People who have a history of liver problems may consider to add portions of dried peas into their diet for preventive measure.

Further analysis the study also indicated that the by product also exert a significant antioxidant activity against the free radical expression and intimated a chain of harmful domino effect in inducing oxidative stress in the liver, which has been considered as a conjoint pathological mechanism.

Dr. Li S, the lead author at the University of Hong Kong, said, "(there is no surprise that) various factors that cause oxidative stress in liver and effects of antioxidants in the prevention and treatment of liver diseases ......".

In deed, application of antioxidants in animal studies has revealed a significant effect in prevented and cured liver diseases involving oxidative stress.

In the concerns of types of phytochemicals may have contributed to the hepatoprotective effect from peas, researchers at the Kyoto Pharmaceutical University launched an investigation to isolate some suspected chemical compounds from the young seedpods of garden peas, showed that

1. Not all chemicals isolated exerted similar in liver protection

2. Some compounds are more effective in compared to others

Further differentiation, researchers suggested, out of many components, Quercetin 3-sophorotrioside, was found to show clinical significantly protective effects on liver injury induced by D-galactosamine and lipopolysaccharide and by carbon tetrachloride in mice study, in compared those of ionone glucoside, pisumionoside, a phenethyl glycoside, sayaendoside, and two acylated flavonol oligoglycosides, pisumflavonosides.

More importantly, in support of the above analysis, researchers at the Changhai Hospital also conducted a study to evaluate the alpha-fetoprotein reactive to Pisum sativum agglutinin levels (AFP-R-PSA) of 24 patients with hepatocellular carcinoma (HCC) and 54 patients with benign liver diseases (BLD) showed that

1. Alpha-fetoprotein levels were higher in patient with liver cancer and suggested that the measured AFP-R-PSA level above 25% may be considered as a value in highly suggestive of HCC with a positive prediction value of 98% accuracy.
2. According to the sensitivity of the test, value of 74% in serum AFP level below 400 micrograms/L was found in 31 patients with a tumor size less than 5cm.
3. In the combined test of (AFP-R-PSA), the detection rate of small HCC was increased from 32% to 87%.

It is amazing that Pisum sativum lectin or agglutinin (PSA), another chemical compound isolated from peas also have a strong effect in prediction of the development and size benign liver diseases (BLD) and liver cancers.

With all information collected from the data of medical literature, we believed,  the efficacy of dried peas in reduced risk and treatment of liver diseases may be attributed to various unknown mechanisms, that are waiting to discover.

These effectiveness also does not assure that patients with liver disease can be cured by adding a significant portions of pea into their diet, because of the small sample sizes and only ingredients isolated from peas were used to perform these testing in all studies. 

But taking together, it is safe to conclude that intake of dried peas may have a profound and positive potency in induced hetapoprotective against liver diseases.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Bioassay-guided fractionation of a hepatoprotective and antioxidant extract of peaby-product by Seida AA1, El Tanbouly ND, Islam WT, Eid HH, El Maraghy SA, El Senousy AS.(PubMed)
(2) Medicinal foodstuffs. XXV. Hepatoprotective principle and structures of ionone glucoside, phenethyl glycoside, and flavonol oligoglycosides from young seedpods of garden peas, Pisum sativum L by Murakami T1, Kohno K, Ninomiya K, Matsuda H, Yoshikawa M.(PubMed)
(3) Alpha-fetoprotein reaction to Pisum sativum agglutinin in differentiation of benign liver diseases from hepatocellular carcinoma by Yin ZF1, Tu ZX, Cui ZF, Wu MC.(PubMed)
(4) The Role of Oxidative Stress and Antioxidants in Liver Diseases by Li S1, Tan HY2, Wang N3, Zhang ZJ4, Lao L5, Wong CW6, Feng Y7.(PubMed)

Food Therapy: Coffee, A linear Association to Reduced Risk and Progression of Parkinson's Disease

By Kyle J. Norton


Intake of coffee caffeine regularly are associated to a significantly attenuated risk of neurodegenerative conditions, particular in the onset of Parkinson's diseases, a recent study suggested.

Parkinson's disease is neuro degenerative disease caused by deficiency of the dopamine and.degeneration of the basal ganglia of the brain, affecting muscular normal function.

Dopamine acted as as a neurotransmitter and a precursor of other substances including epinephrine.
is a compound present in the body involved brain function in the roles of reward-motivated behavior.

The basal ganglia (or basal nuclei) having a strong interconnected with the cerebral cortex, thalamus, and brainstem, as well as several other brain areas, is a group of subcortical neurons, of varied origin, in the brains of vertebrates with function involved primarily processing movement related information such as emotions, motivations, and cognitive functions.

Coffee, becoming a popular and social beverage all over the world, particularly in the West, is a drink made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.

According to the Harvard School of Public Health, Boston, in compared population comprised 47,351 men and 88,565 women free of Parkinson's disease, stroke, or cancer at baseline, caffeine intake is associated to reduced risk and progression of PD, in compared the top and bottom one-fifth men participants. No effect is found for decaffeinate coffee intake regardless to numbers of cup consumed.

Caffeine, a chemical stimulant found abundantly in caffeinated products, including tea and coffee is a class of methylxanthine having a profound impact in central nervous system (CNS).

Interestingly, among women, numbers of caffeinated coffee intake daily have a strong implication in attenuated risk of PD linearly, in compared to lowest intake of moderated intake groups.

Further more, a case-control study conducted in western Washington State in 1992-2000. Incident PD cases (n = 210) and controls (n = 347) with frequency matched on gender and age identified from enrollees of the Group Health Cooperative health maintenance organization, returned questionnaires by participants indicated, consumption of 2 cups/day showed a strong expression in reduced risk of PD.

More importantly, in the review of twenty-six studies included: 7 cohort, 2 nested case-control, 16 case-control, and 1 cross-sectional study, the total relative odd ratio for the association between caffeine intake in low to moderate groups and PD was 0.75.

But, in cohort studies, reduced risk of PD significantly decreased if only women participants were considered.

Researchers, at above study revealed that PD risk is associated to a linear relation between levels of caffeine exposure of relative odd ratio of 0.76, per 300 mg caffeine intake.

Finally, some researchers addressed that, in the concerns of PD patients in expression a significant impairment of dopaminergic neuron transmission, caffeine acted as acts as a nonselective adenosine receptor antagonist may have a profound effect in treatment of PD through adenosine A2A receptors function in regulation of glutamate and dopamine release. 

Taking together, there is no doubt that risk of PD has an extremely inverse association to caffeine intake, particular in moderated drinkers.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Can coffee consumption lower the risk of Alzheimer's disease and Parkinson's disease? A literature review by Wierzejska R1.(PubMed)
92) Prospective study of caffeine consumption and risk of Parkinson's disease in men and women by Ascherio A1, Zhang SM, Hernán MA, Kawachi I, Colditz GA, Speizer FE, Willett WC.(PubMed)
(3) Parkinson's disease risks associated with cigarette smoking, alcohol consumption, and caffeine intake by Checkoway H1, Powers K, Smith-Weller T, Franklin GM, Longstreth WT Jr, Swanson PD.(PubMed)
(4) Association of coffee and caffeine intake with the risk of Parkinson disease by Ross GW1, Abbott RD, Petrovitch H, Morens DM, Grandinetti A, Tung KH, Tanner CM, Masaki KH, Blanchette PL, Curb JD, Popper JS, White LR.(PubMed)

Food Therapy: Beet or Beetroot, A Functional Food in Reduced Risk and Treatment of Inflammatory Bowel Disease

Kyle J. Norton


Beet or Beetroot, may have a potential effect in ameliorated abnormal function of white blood cells such as neutrophils in reduced risk and treatment of inflammatory bowel disease.

Inflammation is a natural process of immune defense to remove injurious agents, cells and tissues from the body.

Inflammatory bowel disease is the boarder term of conditions characterized by chronic inflammation of intestines, including ulcerative colitis and Crohn disease.

Beet, best known as the beetroot or garden beet and belonging to the amaranth family, is a perennial plant with leafy stems growing to 1–2 m tall.

According to the Poznan University of Medial Science, beetroot (Beta vulgaris var. rubra) products and their major component betanin exhibited antioxidant activities against abnormal neutrophils in modulated reactive oxygen species (ROS) production and DNA damage, in healthy subjects.

The efficacy of betanin in reduced reactive oxygen species (ROS) expression is the result of  exerting antioxidant free radical scavenging and neutralizing activities by slowed down or prevented initiation of free radical chain reaction.

Additionally, betanin, as a major phytochemical also ameliorated the elevated ROS expression in promoted oxidative stress which was found to have a strong implication to cause cellular DNA damage. Some researchers suggested that betanin reduced risk of cellular DNA damage.probably through inter influenced the pro apoptotic caspase-3 in the action of release of ROS and apoptotic cell death.

In deed, activities of betanin in attenuated risk of over expression of ROS in induction of DNA also may be an extrinsic way of the phytochemical in exerting anti-inflammatory and potentially cancer preventive activity.

Further analysis and taking into account of other con founders, researchers once again indicated that betanin with concentration of 100 μM for 24 h, inhibited pro inflammatory expression in ulcerative colitis (UC) and Crohn's disease (CD) patients by protecting the digestive tract that can be observed through action in decreased oxidative DNA damage and promoted apoptosis in neutrophils.

In fact, betaine and other phytochemical baicalein have shown to provide various health benefits to organism in many ways, including down-regulation of inflammation against colitis-associated colon tumorigenesis in tested animal.

In case of anti inflammation, both betaine and baicalein also found to demonstrate a magnificent impact in regulation of the pro inflammatory cytokins such as IL-1β, PGE2, and TNF-α in NF-ĸB activation beside activities in inhibited expression of ROS.

Interestingly, in patients with ulcerative colitis, arabino-oligosaccharides (AOS) derived from sugar beet pulp, stimulated Bifidobacterium spp. and Lactobacillus spp. accompanied by a high production of acetate in eliciting anti-inflammatory responses, thus attenuating inflammatory conditions in UC patients.

The observation illustrated that beet may have a potential in acting as prebiotic to enhance the growth of beneficial microorganisms in the intestines, thus reducing.risk of flare-ups in UC patients.

Furthermore, arabino-oligosaccharides (AOS) also showed to elevate the failure of local anaesthesia in inflamed tissues through lowering of intestinal pH

The findings of improved antioxidant in attenuated free radical in induction of DNA and promotion of abnormal expression of neutrophils, as well as acting as prebiotic suggested that beet may be considered as functional food in reduced risk of chronically digestive inflammatory diseases, particularly in inflammatory bowel disease.

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Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) DNA damage and apoptosis in blood neutrophils of inflammatory bowel diseasepatients and in Caco-2 cells in vitro exposed to betanin by Zielińska-Przyjemska M1, Olejnik A2, Dobrowolska-Zachwieja A3, Łuczak M4, Baer-Dubowska W1.(PubMed)
(2) Modulation of Colitis-associated Colon Tumorigenesis by Baicalein and Betaine by Kim DH1, Sung B1, Chung HY1, Kim ND1.(PubMed)
(3) In vitro fermentation of sugar beet arabino-oligosaccharides by fecal microbiota obtained from patients with ulcerative colitis to selectively stimulate the growth of Bifidobacterium spp. and Lactobacillus spp by Vigsnæs LK1, Holck J, Meyer AS, Licht TR.(PubMed)
(4) Anti-inflammatory activity of baicalein in LPS-stimulated RAW264.7 macrophages via estrogen receptor and NF-κB-dependent pathways by Fan GW1, Zhang Y, Jiang X, Zhu Y, Wang B, Su L, Cao W, Zhang H, Gao X.(PubMed)