Holistic Health Articles and Research Related to Herbal Medicines, Foods and Phytochemicals

Tuesday 5 September 2017

Herbal Therapy: Aloe Vera, The Whole Food Medicine Exhibited Anti Hypertensive Effects

By Kyle J. Norton

The use of plants for healing purposes has been predated long before the existence of modern medicine. Herbal plants have formed a fundamental source for conventional medicine in discovery of single ingredient medication, including aspirin (from willow bark), quinine (from cinchona bark), and morphine (from the opium poppy)......

Good news to people with hypertension, Aloe Vera may be a potential and therapeutic agent for lowering high blood pressure a renowned University study suggested.

Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan. It has become very popular for commercial cultivation due to enormous health benefits. Aloe vera has also been used in herbal medicine in treating many kinds of disease, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, anhe d elevated of cholesterol, etc.

Hypertension is a condition of abnormal high blood pressure, leading to symptoms of headaches, shortness of breath or nosebleeds......

According to the Hamdard University ,aloeemodin, aloin A, a chemical compound found in Aloe Vera showed to express hypotensive effects by lower mean arterial blood pressure by 26 %, 52 %, and 79 % in the corresponding doses of 0.5, 1, and 3 mg/kg in animal study.

Dr. Saleem R, the lead author of the study suggested that Aloeemodin has emerged as a potent hypotensive agent in current pharmacological investigation.

In a total of In a double-blind, placebo-controlled, crossover study, healthy, Aloe-emodin, another major chemical compound\ inhibited vascular smooth muscle stiffness, a condition in the development of hypertensio, involved cell in support structural and biochemical and interior surface of blood vessels.

In hypertension, increased large-artery stiffness is partly due to intrinsic mechanical properties of vascular smooth muscle cells.

More importantly, a smooth muscle cells derived from hypertensive and control rats study, treatment of Aloe-emodin also significantly reduced hypertension by improving elastic value of vascular smooth muscle cell , through it effects on vascular smooth muscle cell cytoskeletal proteins in regulated function of cell division.

Other researchers suggested that the anti hypertensive properties of Aloe-emodin may be a result of inhibition of tonic tension and regulated apoptosis, pro- and anti-apoptotic activities on vascular smooth muscle cells.

With all the information collected, Aloe Vera may have an anti hypertensive effect in regulated protein in cell production on vascular smooth muscle which is a main cause of high blood pressure,but more precised understanding may be necessary to reassess this pharmaceutical value.

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Hypotensive effect of chemical constituents from Aloe barbadensis by Saleem R1, Faizi S, Siddiqui BS, Ahmed M, Hussain SA, Qazi A, Dar A, Ahmad SI, Qazi MH, Akhtar S, Hasnain SN.(PubMed)
(2) Increased vascular smooth muscle cell stiffness: a novel mechanism for aortic stiffness in hypertension by Sehgel NL1, Zhu Y, Sun Z, Trzeciakowski JP, Hong Z, Hunter WC, Vatner DE, Meininger GA, Vatner SF.(PubMed)
(3) Emodin inhibits tonic tension through suppressing PKCδ-mediated inhibition of myosin phosphatase in rat isolated thoracic aorta by Lim KM1, Kwon JH, Kim K, Noh JY, Kang S, Park JM, Lee MY, Bae ON, Chung JH.(PubMed)

Monday 4 September 2017

Food Therapy: Coffee, Reduced Risk of Type 2 diabetes for Every Cup/Day Intake

By Kyle J. Norton

In compared to herbal medicine, food therapy even takes longer to ease symptoms, depending to stages of the treatment which directly address to the cause of disease.

Good news for coffee lover, your risk of diabetes is significant reduced in compared to non coffee drinking population, a respectable researcher indicated

Coffee, a popular and social beverage all over the world, particular in the West, is a drink made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.

Diabetes is a medical condition characterized by insufficient insulin entering the bloodstream to regulate the glucose, either caused by cells in pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.

In the reviewed literature of 20 prospective studies with 1,109,272 study participants and 45,335 cases of type 2 diabetes included in the analysis with follow-up duration ranged from 10 months to 20 years, coffee intake is inversely associated to risk of type 2 diabetes.

Compared with no or rare coffee consumption, the range of relative risk (RR; 95% CI) for diabetes significant lower in all studies was 0.92, 0.85 0.75, 0.71, 0.67 respectively for people who have 1-6 cups/day in all reviewed studies.

Both caffeinated and decaffeinated coffee showed an insignificant difference in relative risk but inversely diabetic development in a dose-response manner.

According to the Zhejiang University, coffee consumption reduced risk of type II diabetes may involve expression on different mechanistic factors, inclding glucose tolerance, insulin sensitivity, insulin resistance, glucose-6-phosphatase, intestinal glucose absorption, antioxidant activity, inflammatory biomarkers, nuclear factor-κB inhibition, glucose uptake, glucose homeostasis, glucose metabolism, and insulin secretion.

Dr. Akash MS, the head researcher saids, " the experimental and epidemiologic evidences presented here elucidate the protective effects of coffee consumption on T2DM, involving multiple preventive mechanisms".

Other, in the analysis of risk of autoimmune diabetes with coffee intake in adults, proposed that although consumption of coffee showed an inverse association with type II diabetes through improving the production of high glutamic acid decarboxylase antibody, the general trend was weak.

Risk of latent autoimmune diabetes in adults is reduced even further with additional cup of coffee per day. the study also indicated.

The finding evidences suggested that coffee with caffeine or caffeine showed a strong protective effect against early onset of type 2 diabetes, and risk of T2DM decreased even more for every cup/day increment in coffee intake, expressed by dose-response analysis.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Caffeinated and decaffeinated coffee consumption and risk of type 2 diabetes: a systematic review and a dose-response meta-analysis by Ding M1, Bhupathiraju SN, Chen M, van Dam RM, Hu FB.(PubMed)
(2) Effects of coffee on type 2 diabetes mellitus by Akash MS1, Rehman K2, Chen S3.(PubMed)
(3) Coffee consumption and the risk of latent autoimmune diabetes in adults--results from a Swedish case-control study by Löfvenborg JE1, Andersson T, Carlsson PO, Dorkhan M, Groop L, Martinell M, Rasouli B, Storm P, Tuomi T, Carlsson S.(PubMed)

16 Popular Health Benefits of Asparagus

By Kyle J. Norton

Asparagus is a flowering plant belong to species the genus Asparagus, native to the western coasts of northern Spain, north to Ireland, Great Britain, and northwest Germany, northern Africa and western Asia, used from early times as a vegetable and medicine, because of its delicate flavor and diuretic properties.

Chemical constituents

essential oils, asparagine, arginine, tyrosine, flavonoids (kaempferol, quercetin, and rutin), resin, and tannin.......

Side effect
The vegetable may cause allergic effects and temporarily smelly urination.
Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Food Therapy: Asparagus, the Natural Whole Food with Antidiarrhoeal effects

By Kyle J. Norton

Whole food(herbal medicine) used as medical treatment, linking health benefits in prevention, management and treatment of diseases has induced much interests in today renowned scientists.
But many researchers have raised question of herbal quality, because geographic differences, time of grown and harvest, etc. may effect their's potency. I do believe, these questions can only be answered by experience herbalists.

Recent study by the renowned institute suggested that Asparagus racemosus processed an antidiarrheal effect through ameliorating the discharge from the bowel.

Asparagus is a flowering plant belong to species the genus Asparagus, native to the western coasts of northern Spain, north to Ireland, Great Britain, and northwest Germany, northern Africa and western Asia, used from early times as a vegetable and medicine, because of its delicate flavour and diuretic properties.

Diarrhoea is condition of frequent discharge of feces in liquid form.

According to the K.P. College of Pharmacy, Asparagus racemosus wild root extract used traditional herbal medicine exerted the antidiarrhoeal potency against several experimental models of diarrhoea in model animals, similar to those of conventional medicine such as loperamide.

This efficacy is attributed to the root extracts in mediation of Prostaglandin E2 (PGE2), a principal hormone in expression of inflammatory diseases.

Dr. Venkatesan N. the lead researcher said, "The plant extracts showed significant (P < 0.05) inhibitor activity against castor oil induced diarrhoea and PGE2 induced enteropooling in rats when tested at 200 mg/kg. Both extracts also showed significant (P < 0.001) reduction in gastrointestinal motility ".

In support of the above study, the test of animal model on Alpha-2 blocker (see alpha(2)-adrenoceptor) experimentally-induced diarrhoea and ulceration, showed a positive effect of methanolic extract of Asparagus pubescens root in reduced significantly intestinal propulsive movement, and intestinal fluid accumulation in (500-1500 mg/kg) in dose-dependent manner.

In fact, the antidiarrhoeal effect of asparagus may be a result of modulated the expression of alpha(2)-adrenoceptor in regulated vascular smooth muscle contraction and vasoconstriction though Prostaglandin E2 (PGE2) modification. But further studies may be necessary to validate this potency.

Sources
(1) Anti-diarrhoeal potential of Asparagus racemosus wild root extracts in laboratory animals by Venkatesan N1, Thiyagarajan V, Narayanan S, Arul A, Raja S, Vijaya Kumar SG, Rajarajan T, Perianayagam JB.(PubMed)
(2) Antidiarrhoeal and antiulcerogenic effects of methanolic extract of Asparagus pubescens root in rats by Nwafor PA1, Okwuasaba FK, Binda LG.(PubMed)

Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sunday 3 September 2017

Food Therapy: Asparagus, the Natural Whole Food for Reduced Symptoms and Treatment of Psychological Stress

Modern study suggested that Asparagus extract (ETAS) may have a potential in improved Psychological Stress, the responded to the psychological stress questionnaires, conducted by a renowned institute indicated.

According to the randomized, double-blind, placebo-controlled cross-over trial undertaken in healthy volunteer, oral administration of ETAS (150 mg/d) consumed for 28 day, significantly upregulated the sympathetic nerve activity in reduced Psychological Stress.

Dr. Takanari J, the lead author in the study said, " ETAS significantly increased the number of answers and the number of correct answers in the U-K test, suggesting that it might improve office work performance with swiftness and accuracy under stressful conditions" and "ETAS intake may exert beneficial effects, resulting from well-controlled stress management, in healthy individuals.".

Asparagus is a flowering plant belong to species the genus Asparagus, native to the western coasts of northern Spain, north to Ireland, Great Britain, and northwest Germany, northern Africa and western Asia, used from early times as a vegetable and medicine, because of its delicate flavour and diuretic properties.

A study to investigate the efficacy of the extract against psychological tress, standardized methanolic extract of Asparagus racemosus (MAR) (50, 100, and 200 mg/kg, per oral) administered for 7 days, in comparison to intake of Lorazepam (0.5 mg/kg, intraperitoneal) used as a positive control, conducted by the Indian Institute of Technology (Banaras Hindu University, suggested that the herbal extract improves psychological stress through a physiological modulation of the stress pathways with limited change on monoaminergic systems in comparison to controls.

The study also stated that this efficacy may also be contributed to decrease the plasma corticosterone (CORT) and norepinephrine (NE), levels which control the stress aspect during certain stressful events.

Monoamine is a neurostransmitter including dopamine, noradrenaline, adrenaline and serotonin played an important role in regulated on arousal, emotion and cognition.

Dr. Joshi T and colleagues at the Kumaun University, also expressed the usefulness of ethanolic extract of the roots of A. racemosus in ameliorating restraint stress in induced elevation of blood glucose, triglyceride and cholesterol levels, as well as stress induced variations in levels of lipid peroxidation, nitric oxide, protein and glutathione content in mouse brain..

Taking together, Asparagus and its extract may consist a potential effect in reduced psychological stress through expression of stress hormone and antioxidant in a physiological modulation of the stress pathways.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Effect of Enzyme-Treated Asparagus Extract (ETAS) on Psychological Stress in Healthy Individuals byTakanari J1, Nakahigashi J, Sato A, Waki H, Miyazaki S, Uebaba K, Hisajima T.(PubMed)
(2) Asparagus racemosus modulates the hypothalamic-pituitary-adrenal axis and brain monoaminergic systems in rats by Krishnamurthy S1, Garabadu D, Reddy NR.(PubMed)
(3) Antistress activity of ethanolic extract of Asparagus racemosus Willd roots in mice by Joshi T1, Sah SP, Singh A.(PubMed)

Food Therapy: Coffee, A Potent Beverage for Weight Loss and Weight Management?

By Kyle J. Norton

In compared to herbal medicine, food therapy even takes longer to ease symptoms, depending to stages of the treatment which directly address to the cause of the disease.

Coffee, a popular drink may be an excellent beverage for induced weight loss and weight management, a reviewed study by respectable university revealed.

Coffee, emerging as a popular and social beverage all over the world, particular in the West, is a drink made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.

Weight loss is an intentional reduction of the total body mass, according to the definition stated by medicine, health, or physical fitness experts.

According to the University of Exeter, in the reviewed data from human clinical trials, differentiated 8 eligible trials, green coffee extract (GCE) have moderated or significant effect in reduced weight loss in compared to placebo.

In rat model, 48t rats fed with either a control diet with water (C) or a control diet with a coffee solution (CF). At the end of week 4, animals in each dietary group were subdivided into three exercise groups: before exercise (BE), during exercise (DE), and after exercise (AE), group fed with coffee solution showed a significant in reduced total weight compared diet with water group.

The efficacy of dietary coffee in decreased total weight loss may be attributed to the extract function in stimulated the production of antioxidant in suppressed free radical expression. as well as increasing total cholesterol.

Dr. Choi EY the lead author said,"freeze-dried instant coffee can promote activities of antioxidant enzymes and induce weight loss but also aggravate the plasma cholesterol profile in rats".

Additionally, in the compared the daily consumption of coffee and caffeinated beverages between 494 weight loss maintainers and 2129 individuals from the general population, consumed significantly more cups of coffee are found in the weight loss maintainers than the general population group.

Other researchers insisted that the efficacy of coffee in induced weight loss, probably due to activities of caffeine and other chemical constituents of coffee, such as chlorogenic acid and quinides.

Collective findings suggested that coffee may have a potentially therapeutic property in weight deduction. But some reviewed trials were associated with a high risk of bias. poor methodological quality, therefor, more studies are necessary to confirm the promising validity, some researchers suggested.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Sources
(1) The use of green coffee extract as a weight loss supplement: a systematic review and meta-analysis of randomised clinical trials by Onakpoya I1, Terry R, Ernst E.(PubMed)
(2) Caffeine intake is related to successful weight loss maintenance by Icken D1, Feller S2, Engeli S3, Mayr A4, Müller A1, Hilbert A5, de Zwaan M1.(PubMed)
(3) Freeze-dried instant coffee can promote the activities of antioxidant enzymes and induce weight loss but also aggravate the plasma cholesterol profile in rats byChoi EY1, Park SY, Cho YO.(PubMed)
(4) Coffee, diabetes, and weight control by Greenberg JA1, Boozer CN, Geliebter A.(PubMed)
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Biography

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

19 Overwhelming Health Benefits of Cruciferous vegetables

Kyle J. Norton

Cruciferous vegetables are the group of vegetables belonging to the family Brassicaceae, including cauliflower, cabbage, cress, bok choy, broccoli etc.

Chemical constituents

Glucosinolates, dithiolthiones, indoles , glucoraphanin, s-methyl cysteine sulfoxide, isothiocyanates, indole-3-carbinol,......