Holistic Health Articles and Research Related to Herbal Medicines, Foods and Phytochemicals

Thursday 13 July 2017

Herbal Therapy: Cayenne, the Natural Whole Herb Medicine for treatment of Metabolic dysregulation

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Whole food(herbal medicine) used as medical treatment, linking health benefits in prevention, management and treatment of diseases has induced much interests in today renowned scientists.
Many researchers has raised a question of their's effectiveness because of quality of the herbs due to geographic differences, time of grown and harvest, etc. I do believe that these questions can only be answered by experience herbalist.

Cayenne may be the next herbal medicine in reduced risk and treatment of metabolic dysregulation, recent study suggested

Cayenne is also known as Cayenne Pepper, a red, hot chili pepper, belonging to Capsicum annuum, the family Solanaceae, native to sub-tropical and tropical regions. It has been used in traditional medicine to increases metabolism, enhance circulatory system and stomach and the intestinal tract, adjust blood pressure, lower LDL cholesterol and triglycerides, treat frostbite, muscles, arthritis, rheumatism, low back pain, strains, sprains, bruises and neuralgia, etc.

Metabolic dysregulation refers to abnormal function of the body in regulation of glucose tolerance, fasting glucose, insulin resistance, dyslipidemia,...., leading to insulin resistance, type 2 diabetes, and fatty liver disease.

Capsaicin, the major chemical compound used dietary supplement attenuated metabolic dysregulation in genetically obese diabetic mice through by enhancing expression of modulation of glucose and lipid metabolism involving its receptors.

In obesity-induced inflammation and the development of obesity-related metabolic disorders, cayenne capsaicin suppressed inflammatory responses in inducing glucose intolerance and enhancing fatty acid oxidation in fat tissues, affecting insulin resistance.

The chemical compound involvement in reduced visceral adipose fat, also lowered serum levels of fasting glucose, total cholesterol, and triglycerides, probably through limited fat accumulation in adipose tissues and reduced inflammation and increased insulin sensitivity.

Dr. Leung FW. said," Clinical evidence supports a role of capsaicin as an anti-obesity agent. Both oral and gastrointestinal exposure to capsaicin increase satiety and reduce energy and fat intake and reduction in visceral abdominal fat" and "Thermogenesis and lipid metabolism-related proteins are altered upon capsaicin treatment in white adipose tissue".

Intake of cayenne for weight loss treatment induced reduction in visceral abdominal fat may also improve the metabolic regulation. Quality of doses should only be given by specialist to prevent toxicity.

Food Therapy: Celery, the Natural Whole Food in Ameliorated Pain of Dysmenorrhea

In the randomized, double-blind, placebo-controlled pilot trial among 180 female students at Isfahan University dormitory aged 18 to 27 who suffered from primary dysmenorrhea, the combination decode expressed significant reductions in pain scores and pain duration scores in the groups that took SCA (P < . 001), in comparison to group who took mefenamic acid, used to treat mild to moderate pain.

Dr. Nahid K, the researcher said, "The decrease in pain score was reflected by a significant reduction in other drug use among the treatment groups compared with the women in the placebo group" and "The magnitude of the reduction was significantly greater in the SCA group than in the mefenamic acid and placebo groups".

Usr-i-tamth in Unani (Greco-Arabic) decode, included celery, used in traditional medicine in treating pain associated with menstruation.

In the review of the Cochrane database, PubMed/Google Scholar, and other websites for articles on complementary and alternative medicine, the herbal formula exerted analgesic effect in attenuated abnormal temperament, menstrualirregularities/uterine diseases, particular in management of menstrual pain/dysmenorrhoea.

Although some herbal medicine and formula may have a powerful effect in ameliorated painful menstruation, further data collection is necessary to prevent adverse drug reactions among women using herbal medicines for reproductive health.

(2) Management of Usr-i-Tamth (Menstrual Pain) in Unani (Greco-Islamic) Medicine by Sultana A1, Lamatunoor S2, Begum M3, Qhuddsia QN4.(PubMed)
(3) Medicinal plants used for menstrual disorders in Latin America, the Caribbean, sub-Saharan Africa, South and Southeast Asia and their uterine properties: a review by van Andel T1, de Boer HJ2, Barnes J3, Vandebroek I4.(PubMed)

Wednesday 12 July 2017

Herbal Therapy: Cinnamon: The Best Whole food Medicine for Prevention, management and Treatment of Cervical Cancer

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Whole food(herbal medicine), linking health benefits in prevention, management and treatment of diseases has placed an important role in human history over many centuries. The finding of whole food medication by renowned scientists all over world to replace the single ingredient of Western medicine with little or no side effect has been difficult due to no commercial benefit and patent right to producers.

Cinnamon may be the Best Whole food Medicine for Prevention, management and Treatment of Cervical Cancer.
According to the Manipal University, Eugenol, a potential chemopreventive agent, one of the a component of cinnamon possesses antiseptic, analgesic, antibacterial, and anticancer properties in expression of apoptosis and inflammation against cervical cancer cell lines.

Cinnamon is a spice derived from the inner bark of tree, native to South East Asia, of over 300 species of the genus Cinnamomum, belonging to the familyLauraceae, use in herbal and traditional medicine as anti-fungal and bacteria level, to improve reproductive organ, prevent flatulence and intestinal cramping, and to treat indigestion, diarrhea, bad breath, headache, migraine, etc.

In SiHa cancer cell line, established from cancerous tissues of the cervix uteri, methanol extracts of Gymnema sylvestre (GS) leaves and Cinnamomum zeylanicum (CZ) bark exhibited dose-dependent cytotoxicity, inducing apoptosis.

Other researchers suggested that the effective use of cinnamon against tumor activity, particular in cervical cancer cell line SiHa may be the result in reduced number of colonies, risk of migration potential through down regulated normal physiological processes.

Dr. Kwon HK, the lead researcher at the Gwangju Institute of Science and Technolog, insisted, Cinnamomum cassia bark,.. containing several active components such as essential oils, expressed anti-tumor effect via enhanced pro-apoptotic and inhibition of pro inflammatory activities, in vitro and in vivo mouse melanoma model.

In fact, the potential anti-tumor effects of cinnamon may be due to increased anti-tumor activities in suppression of progression by increasing the levels of cytolytic molecules and cytotoxic activity.

Although the whole herb medicine may be a potential agent for reduced risk and treatment of cervical cancer, oral use of cinnamon should be taken with care and only prescribed by herbalist.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) Eugenol enhances the chemotherapeutic potential of gemcitabine and induces anticarcinogenic and anti-inflammatory activity in human cervical cancer cells by Hussain A1, Brahmbhatt K, Priyani A, Ahmed M, Rizvi TA, Sharma C.(PubMed)
(2) Biomolecule-loaded chitosan nanoparticles induce apoptosis and molecular changes in cancer cell line (SiHa) by Sujima Anbu A1, Velmurugan P2, Lee JH3, Oh BT4, Venkatachalam P5.(PubMed)
(3) Aqueous cinnamon extract (ACE-c) from the bark of Cinnamomum cassia causes apoptosis in human cervical cancer cell line (SiHa) through loss of mitochondrial membrane potential by Koppikar SJ1, Choudhari AS, Suryavanshi SA, Kumari S, Chattopadhyay S, Kaul-Ghanekar R.(PubMed)
(4) Cinnamon extract induces tumor cell death through inhibition of NFkappaB and AP1 by Kwon HK1, Hwang JS, So JS, Lee CG, Sahoo A, Ryu JH, Jeon WK, Ko BS, Im CR, Lee SH, Park ZY, Im SH.(PubMed)
(5) Cinnamon extract suppresses tumor progression by modulating angiogenesis and the effector function of CD8+ T cells by Kwon HK1, Jeon WK, Hwang JS, Lee CG, So JS, Park JA, Ko BS, Im SH.(PubMed)

Herbal Therapy: Cat's claw, The best Whole Herb Medicine for Treatment of Parkinson disease

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Whole food(herbal medicine), linking health benefits in prevention, management and treatment of diseases has placed an important role in human history over many centuries. The finding of whole food medication by renowned scientists all over world to replace the single ingredient of Western medicine with little or no side effect has been difficult due to no commercial benefit and patent right to producers.

Cat's claw found in the tropical jungles of South and Central America, is a genus Uncaria, belonging to the family Rubiaceae, used in traditional medicine over two thousand years as a tonic, contraceptive, anti-inflammatory and infectious agent, and to treat diarrhea, rheumatic disorders, acne, diabetes, cancer and diseases of the urinary tract, etc..

The chemical constituents of Cat's claw include, ajmalicine, akuammigine, campesterol, catechin, carboxyl alkyl esters, chlorogenic acid, cinchonain, corynantheine, corynoxeine, daucosterol, epicatechin, harman, hirsuteine, hirsutine, iso-pteropodine, etc.

Parkinson disease is a type of dementia caused by dysfunction of nerve cells that produce dopamine in the brain, affecting muscle rigidity, tremors, changes in speech and gait.

Uncaria tomentosa may be one of the medical plant used for reduced symptoms and treatment of Parkinson disease.

According to the recent study, AC11 (a standardized aqueous extract of Uncaria tomentosa) exhibited scavenged several types of free radicals, decreased the level of lipid peroxidation and reduced aggregation of α-synuclein by 40%.

Dr. Cosentino C. the lead researcher at the Instituto de Ciencias Neurologicas, said, "Uncaria tomentosa (UT),,... reversed worsening of motor signs in a patient with Parkinson disease after oral intake"

Further study of Cat's Claw (Uncaria tomentosa) also found that the medical plant enhanced DNA repair and immunity in model systems with capability of generated neuroprotective effects in neurons.

Although therapeutic intervention of Cat's claw my exhibit the properties against Parkinson's disease, use of the medicial plant should be taken with care.

Tuesday 11 July 2017

Food Therapy: Celery, the Natural Whole Food Repellent

Believe or not, celery may be used as repellent against insects.

Recent study suggested that celery in different varieties have exhibited significantly repellent effects whiteflies, particular Bemisia tabaci through their phytocemicals in the class of terpene, such as D-Limonene, β-myrcene, and (E)-β-ocimene.

Depending to types of celery, some showed repellent effects relatively higher in volatilization quantities of β-myrcene than of D-limonene.

Celery is a species of Apium graveolens, belonging to the family Apiaceae, cultivated all around the globe as a vegetable. Celery can grow to 1/2 m tall with stalks (leaf on the top) arranging in a conical shape joined at a common base.

In the study of Aedes aegypti L., one of the primary disease vectors spreading various dreadful diseases, essential oil extracted from the seeds of celery showed remarkably effective repellency of the oil leading to 100% protection till 165 min as compared to control, probably due to presence of flavonoids, lactones, and terpenoids.

Dr. Kumar S, the lead researcher said, " celery seed essential oil can be used as an efficient larvicide and repellent against Ae. aegypt" and ' The identification of the bioactive components, their mode of action, and studying effects on non-target organisms and the environment would help in devising mosquito-management strategies".

Furthermore, according ot the Chiang Mai University, G10, a celery (Apium graveolens)-based topical product exhibited not only a similarity in appearance and physical properties, but also provided comparable repellency to that of the fresh preparation against a broad range of mosquito species belonging to various genera, including Aedes, Anopheles, Armigeres, Culex, and Mansonia, in comparison to the commercial (Insect Block 28) and standard (25% DEET) repellents.

In fact, because the G10 formula is a worthwhile product expressed significantly promising results, including highly effective repellency with no potential skin irritation or other side effects, some researchers suggested that the product may be used as a potential natural alternative for personal protection against mosquitoes.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) Repellent Effects of Different Celery Varieties in Bemisia tabaci (Hemiptera: Aleyrodidae) Biotype Q. by Tu H1,2, Qin Y2,(PubMed)
(2) Larvicidal, Repellent, and Irritant Potential of the Seed-Derived Essential oil of Apium graveolens Against Dengue Vector, Aedes aegypti L. (Diptera: Culicidae) by Kumar S1, Mishra M1, Wahab N1, Warikoo R1(PubMed)
(3) Field evaluation of G10, a celery (Apium graveolens)-based topical repellent, against mosquitoes (Diptera: Culicidae) in Chiang Mai province, northern Thailand by Tuetun B1, Choochote W, Pongpaibul Y, Junkum A, Kanjanapothi D, Chaithong U, Jitpakdi A, Riyong D, Wannasan A, Pitasawat B.(PubMed)
(4) Celery-based topical repellents as a potential natural alternative for personal protection against mosquitoes by Tuetun B1, Choochote W, Pongpaibul Y, Junkum A, Kanjanapothi D, Chaithong U, Jitpakdi A, Riyong D, Pitasawat B.(PubMed)

Food Therapy: Garlic - The Whole Food Medicine for Antiplatelet Aggregation

Antiplatelet activity is the effect in decreased platelet aggregation and inhibited thrombus formation.

According to the Ochanomizu University, sulfur-containing compounds in garlic not only inhibited arachidonic acid metabolism but also suppressed aggregation in association with the function of the platelet plasma membrane.

In vitro, garlic mechanisms of action may be comparable to that of the clinically used drug clopidogrel, as the herb exerts antiaggregatory effects. Garlic extracts are acting by inhibition of the ADP pathway, an important physiological agonist of normal hemostasis and thrombosis.

Dr. MacDonald JA lead of researcher said, " The ability of an aromatic disulfide to inhibit platelet aggregation can be enhanced by appending an electron-withdrawing group to the aromatic ring. The results presented establish that the aromatic thiosulfonate is a very effective inhibitor of platelet aggregation"

Beside the sulfur compound, Ajoene, (E,Z)-4,5,9-trithiadodeca-1,6,11-triene 9-oxide, isolated from alcoholic extracts of garlic reversibly inhibited platelet aggregation through platelet deposition on severely damaged vessel wall but not affected platelet adhesion.

In fact, in the comparsion of the effect of the Garlic Pill with Plavix on Platelet Aggregation and Bleeding Time, groups treated with 1200 or 2400 mg garlic inhibited platelet aggregation substantially, through increased time of bleeding.

The use of garlic supplement should be taken with care for patients who are taking Anticoagulant as garlic may increase risk of bleeding. Also, patients with ulcer should consult with their doctors.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) Improving upon the in vitro biological activity of antithrombotic disulfides by MacDonald JA1, Marchand ME, Langler RF.(PubMed)
(2) Inhibitory effect of sulfur-containing compounds in Scorodocarpus borneensis Becc. on the aggregation of rabbit platelets by Lim H1, Kubota K, Kobayashi A, Seki T, Ariga T.(PubMed)
(3) Antiplatelet activity of Allium ursinum and Allium sativum by Hiyasat B1, Sabha D, Grotzinger K, Kempfert J, Rauwald JW, Mohr FW, Dhein S.(PubMed)
(4) A garlic derivative, ajoene, inhibits platelet deposition on severely damaged vessel wall in an in vivo porcine experimental model by Apitz-Castro R1, Badimon JJ, Badimon L.(PubMed)

Monday 10 July 2017

Herbal Therapy: Chamomile, The best Whole herb Medicine in Expression of Sedative Activities

Sedation is a form of medicine in induced calm and sleep.

The herbal medicine is also known as camomile, common name of many species daisy-like plants in the family Asteraceae, used in traditional medicine as antispasmodic and anti-inflammatory constituents and to treat menstrual cramps and sleep disorders, reduce cramping and spastic pain in the bowels, relieve excessive gas and bloating in the intestine, etc.

In support of the sedative effect, chamomile cream also is found to reduce episiotomy pain sedately in primiparous women, according to a triple blind clinical trial performed on 114 eligible women at Ommolbanin Hospital in Mashhad, Iran in 2014.

Dr. McKay DL said, " Chamomile has moderate antioxidant and antimicrobial activities, and significant antiplatelet activity Animal model studies indicate potent antiinflammatory action, some antimutagenic and cholesterol-lowering activities, as well as antispasmotic and anxiolytic effects" and "(Unfortunately) However, human studies are limited, and clinical trials examining the purported sedative properties of chamomile tea are absent."

In fact, in the investigated hypnotic activities of chamomile and passiflora extracts using sleep-disturbed model rats, researcher at the Okayama University insisted, chamomile extract at a dose of 300 mg/kg exerted significantly decrease sleep latency.
The study also suggested, chamomile extract is a herb having benzodiazepine-like hypnotic activity.

Taking altogether, Chamomile may be helpful to aid calm and sleep through its sedative effects, but intake of correct amount should only be given by qualified herbalist