Monday 27 January 2014

Herbal Catnip (Nepeta cataria) and memory

Catnip is also known as catswort, or catmint, a plant of Nepeta, belonging to the family of Lamiaceae, native to Europe and Asia. It has been use in herbal medicine as insect repellant and to treat digestive disorders, children restlessness and nervousness, fevers, cold and flu, skin irritations stimulate sweating, promote menstruation, etc..
Central nervous system include is the part of the nervous system of the brain and spinal cord with function of integrates information it receives from for the entire nervous system, and control all the workings of your body.

Ingredients
Beside the major constituent of terpenoid nepetalactone, the herb also contains α-Pinene, β-Pinene, Cyclohexen-1-yl-methyl ketone, Triplal, Thymol, Nepetalactone, Nepetalactone, etc.

The Benefits

Evidences emerged in the research community that certain ingredients plants and vegetable may  improve the cognitive function by enhancing theirs antioxidant activity. Study of the effects of menthoides aqueous extract on memory retention and retrieval of mice using passive avoidance apparatus, the result showed that the extract has exerted its antioxidant effect by enhancing the  memory retention and retrieval, these may be a result of the effects of the herb's rosmarinic acid, caffeic acid and phenolic acids.

Side effects1. Overdose of Catnip may cause central nervous system depression.
2. Long-term exposure induced tolerance to stereotypic behavior, catalepsy and sleeping time, and increased the susceptibility to seizures.
3. Catnip may interacts with other medication if used  on a daily basis
4. Etc.


Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Back to Herbal Therapy http://kylejnorton.blogspot.ca/p/herbal-therapies.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References
(1) Chemical Composition and Antimicrobial Activities of Essential Oils from Nepeta cataria L. against Common Causes of Food-Borne Infections by Kamiar Zomorodian, Mohammad Jamal Saharkhiz, Samaneh Shariati, Keyvan Pakshir, Mohammad Javad Rahimi,  and Reza Khashei(PubMed)
(2) Effects of Nepeta menthoides aqueous extract on retention and retrieval of memory in mice by Sarahroodi S, Jafari-Najafi R, Nasri S, Rohampour K, Maleki-Jamshid A, Esmaeili S.(PubMed)
(3)  Investigation of the chemical composition-antibacterial activity relationship of essential oils by chemometric methods, by Miladinović DL, Ilić BS, Mihajilov-Krstev TM, Nikolić ND, Miladinović LC, Cvetković OG.(PubMed)
(4) Croton zehntneri: possible central nervous system effects of the essential oil in rodents`by Batatinha MJ, de Souza-Spinosa H, Bernardi MM(PubMed)
(5) `Behavioral effects of acute and long-term administration of catnip (Nepeta cataria) in mice`by Massoco CO, Silva MR, Gorniak SL, Spinosa MS, Bernardi MM(PubMed)
 



Herbal Cayenne and cancers

Cayenne is also known as Cayenne Pepper, a red, hot chili pepper, belonging to Capsicum annuum, the family Solanaceae, native to sub-tropical and tropical regions. It has been used in traditional medicine to increases metabolism, enhance circulatory system and stomach and the intestinal tract, adjust blood pressure, lower LDL cholesterol and triglycerides, treat frostbite, muscles, arthritis, rheumatism, low back pain, strains, sprains, bruises and neuralgia, etc.
Cancer is a class of diseases in which a group of cells growing and multiplying disordered and uncontrollable way in our body, have become progressively worse and damaged other healthy tissues, sometimes spreads to other organs in the body via lymph or blood and results may be in death.

Ingredients
The chemical constituents of Cayenne include capsaicin,  capsacutin oil, solaine, xanthenes, oleic acid, palmitic acid, etc.

The benefits
Capsaicin, a chemical constituent found in cayenne is found to be effective in significantly reduced cell proliferation and induced cell death. In the exposure to human KB cancer cells, Capsaicin exerted its anti cancer effect by induced growth inhibition of KB cells apoptosis as it promotes the disruption of the mitochondrial membrane potential as well as activation of caspase 9, 3 and poly-(ADP-ribose) polymerase in KB cells. Other in the study of the same but with extract from spices like chili pepper, cloves, black pepper and black cuminto compare the in vitro anticancer activities of aqueous and ethanolic extracts against the TE-13 (esophageal squamous cell carcinoma) cell line, suggested that
all extracts showed cytotoxic activity but aqueous extracts were found to be more potent than alcoholic extracts.

The Side Effects
1. It may cause allergic reaction in young children
2. It may also cause hypertense response if overdosed.
3. It may promote symptoms of acute anal fissure.
4. It may cause burning sensation to certain people in the first taste
5. Do not use cayenne pepper in young children
6. Etc.


Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Back to Herbal Therapy http://kylejnorton.blogspot.ca/p/herbal-therapies.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References
(1) "Severe pepper allergy in a young child" by Gimenez L, Zacharisen M(PubMed))
(2) Mechanisms underlying the hypertensive response induced by capsaicin" by Dutta A, Deshpande SB.(PubMed)
(3) Consumption of red-hot chili pepper increases symptoms in patients with acute anal fissures" by Gupta PJ.(PubMed)
(4) Capsaicin induces cell cycle arrest and apoptosis in human KB cancer cells by Lin CH, Lu WC, Wang CW, Chan YC, Chen MK.(PubMed)
(5) Cytotoxic potential of Indian spices (extracts) against esophageal squamous carcinoma cells.

Dwivedi V, Shrivastava R, Hussain S, Ganguly C, Bharadwaj M.(PubMed)

Sunday 26 January 2014

Cruciferous vegetables and breast cancer

Cruciferous vegetables are the group of  vegetables belonging to the family Brassicaceae, including cauliflower, cabbage, cress, bok choy, broccoli etc.
Breast cancer (malignant breast neoplasm) is a cancer that starts in the tissues of the breast either from the inner lining of milk ducts (Ductal carcinoma) or the lobules (Lobular carcinoma) that supply the ducts with milk. there is also rare cases that breast cancer starts in other areas of the breast.

Nutrients and chemical constituents
1. Carbohydrates
2. Sugars
3. Dietary fiber
4. Omega 3 fatty acid
5. Protein
6. Beta-carotene
7. Lutein and
8. Zeaxanthin
9. Thiamine (Vitamin B1)
10. Riboflavin (Vitamin B2)
11. Niacin (Vitamin B3)
12. Pantothenic acid (B5)
13. Vitamin B6
14. Folate (Vit. B9)
15. Vitamin C
16. Calcium
17. Tryptophan
18. Iron
19. Magnesium
20. Phosphorus
21.Potassium
22. Zinc
23. Etc.
Its chemical constutuents include  glucosinolates, dithiolthiones, indoles , glucoraphanin, s-methyl cysteine sulfoxide, isothiocyanates, indole-3-carbinol, etc..

The benefits
 In 2010, over 250,000 new cases of breast cancer were diagnosed in women in the U.S. alone and the risk of getting invasive breast cancer during life time of a women is 1/8. isothiocyanates, chemical compound derived from Cruciferous vegetables has shown to be effective in anti cell proliferation, apoptosis cancer cells. In the study of the cytotoxicity of human breast cancer MCF-7 and human mammary epithelium MCF-12A cell lines, the derived compound found in isothiocyanates exerted its anti breast cancer activity with benzyl isothiocyanate (BITC), beta-phenethyl isothiocyanate (PEITC), Sulforaphane and NITC inhibited the growth of human breast cancer cells and human mammary epithelium cells at concentrations similar to those of the chemotherapeutic drug daunomycin (DNM). Other study indicated that sources of ITCs of  isothiocyanates reduced the risk of  breast cancer risk in menopausal women, through the interaction of the detoxified function of glutathione S-transferases (GSTs). Unfortunately, Depletion of GSTP1 is associated to increased risk of certain cancers.


The Side effects1. People who has over production of IgM immunoglobulins which makes blood thicken should talk to their doctor before taking high amount of broccoli.
2. Allergic reaction??
3. Etc.

References
(1) Dietary organic isothiocyanates are cytotoxic in human breast cancer MCF-7 and mammary epithelial MCF-12A cell lines by Tseng E, Scott-Ramsay EA, Morris ME.(PubMed)
(2) Breast cancer risk in premenopausal women is inversely associated with consumption of broccoli, a source of isothiocyanates, but is not modified by GST genotype by Ambrosone CB, McCann SE, Freudenheim JL, Marshall JR, Zhang Y, Shields PG.(PubMed)
(3) Cruciferous vegetables, the GSTP1 Ile105Val genetic polymorphism, and breast cancer risk by Lee SA, Fowke JH, Lu W, Ye C, Zheng Y, Cai Q, Gu K, Gao YT, Shu XO, Zheng W.(PubMed)

Herbal Cascara Sagrada (Rhamnus purshiana) and Anti viral effects

Cascara sagrada is a species of buckthorn, genus Rhamnus, belonging to the family Rhamnaceae, native to western North America, it's bark has been used in traditional medicine for gastrointestinal support. and it is thought to have a laxative and natural cleansing, etc.,

The immune system is the set of cells and their activity against antigens or infectious agents that comprises of the body's defense system against diseases. The immune system does a great job of keeping people healthy and preventing infections. Beside foods and nutritional supplements, herbs also play a important role in helping the immune system defend against viruses and bacteria attacks.

The Ingredients
The chemical constituents of Cascara Sagrada include Aloe-emodin, Anthrquinone glycosides (Barbaloin Cascarosides A, B, C and D ChrysaloinFrangul), Chrysophanol, Emodin, Heterodianthrones palmidin A, B, and C, dianthrones, Oxanthrone, Rhein, Tannins, etc.

The benefits
Hot glycerin extracts prepared from some herbal plants, including Cascara Sagrada is found to be effective in exerting their anti viral activities including herpes simplex virus type 1 and type 2.  The combined emodin plus Astragalus polysaccharide (APS), showed  a weak but persistent inhibitory effect on HBV replication in vivo, which may function as a supplementary modality in the treatment of hepatitis B infection. In SARS,  Isatis indigotica root extract, five major compounds of I. indigotica root, and seven plant-derived phenolic compounds were tested, only compounds aloe emodin and hesperetin dose-dependently inhibited cleavage activity of the 3CLpro,


The Side effects
1. Cascara Sagrada can be liver toxic.
2. Postal hypertension
Cascara sagrada (CS) has been associated with the development of cholestatic hepatitis, complicated by portal hypertension.
3. Fresh cut, dried bark may cause vomiting and diarrhea.
4. It may cause allergic effect.
5. Etc.


Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Back to Herbal Therapy http://kylejnorton.blogspot.ca/p/herbal-therapies.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


References
(1) Emodin regulates glucose utilization by activating AMP-activated protein kinase by Song P, Kim JH, Ghim J, Yoon JH, Lee A, Kwon Y, Hyun H, Moon HY, Choi HS, Berggren PO, Suh PG, Ryu SH.(PubMed)
(2) Promotion of adiponectin multimerization by emodin: a novel AMPK activator with PPARγ-agonist activity by Chen Z, Zhang L, Yi J, Yang Z, Zhang Z, Li Z.(PubMed)
(3) Emodin, a natural product, selectively inhibits 11beta-hydroxysteroid dehydrogenase type 1 and ameliorates metabolic disorder in diet-induced obese mice by Feng Y, Huang SL, Dou W, Zhang S, Chen JH, Shen Y, Shen JH, Leng Y.(PubMed)

Phytochemical allicin and hypertension

Allicin is phytochemical containing sulfur in the class of organosulfur compound, found abundantly in onion and garlic.
Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood. High blood pressure means raising pressure in your heart.If it stays high over time it can damage the body in many ways.
Blood pressure medications have undoubtedly prevented many deaths from heart disease in the past 30 years, but they have many side effects such as damaging the kidney. If you can control your diet, such as making changes to lifestyle, maintaining ideal weight and diet with low salt, you could do just fine without the drugs.


The health benefits
Allicin, found in garlic and onion may consist an antihypertensive effects by lowering the systolic and diastolic blood pressure. In the study of a popular garlic preparation containing 1.3% allicin at a large dose (2400 mg)  in nine patients with rather severe hypertension, after 5 hours taking the preparation, sitting blood pressure fell 7/16, with a significant decrease in diastolic blood pressure from 5-14 hours after the dose. Other in the study of the hypotensive action of time-released garlic powder tablets (Allicor) and compared with that of regular garlic pills (Kwai) in 84 men with mild or moderate arterial hypertension, the result indicated that both Kwai and garlic powder tablets decrease in systolic blood pressure but no decrease in diastolic blood pressure was observed with Kwai. These different effects may be as a result of the prolonged action of Allicor. 



Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Phytochemical Therapy http://kylejnorton.blogspot.ca/p/phytochemical-therapy.html


 References
(1) Can garlic lower blood pressure? A pilot study by McMahon FG, Vargas R.(PubMed)
(2) Time-released garlic powder tablets lower systolic and diastolic blood pressure in men with mild and moderate arterial hypertension by Sobenin IA, Andrianova IV, Fomchenkov IV, Gorchakova TV, Orekhov AN.(PubMed)

Phytochemical Phytic acid and Diabetes

Phytic acid (Inositol hexaphosphate) are phytichemicasl of the organic acid found abundantly in nuts, sesame seeds, soybeans, wheat, pumpkin, beans, almonds, etc.
Diabetes is defined as a condition caused by insufficient insulin entering the bloodstream to regulate the glucose. It is either caused by cells in pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.

The benefits
In streptozotocin-induced diabetic rats, fed with or without phytic acid supplementation for thirty days, showed a positive effects in lowering spike in random blood glucose, in the same group, serum triglycerides and increased total cholesterol and HDL was also reduced. On the levels of blood glucose and some enzymes of carbohydrate and lipid metabolism with rats fed formulated diets supplemented with zinc or without zinc, formulated diets supplemented with zinc plus phytic acid extracted from sweet potato (Ipomea batatas) or commercial phytic acid respectively, showed a lowered blood glucose levels in Phytic acid extract consumption from sweet potato and commercial phytic acid plus zinc supplement. These results may indicted that the use of sweet potato diet in diabetic management.



Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Phytochemical Therapy http://kylejnorton.blogspot.ca/p/phytochemical-therapy.html


References
(1) The potential benefits and adverse effects of phytic Acid supplement in streptozotocin-induced diabetic rats by Omoruyi FO1, Budiaman A1, Eng Y1, Olumese FE2, Hoesel JL3, Ejilemele A3, Okorodudu AO (PubMed)
(2) The effect of phytic acid on the levels of blood glucose and some enzymes of carbohydrate and lipid metabolism by Dilworth LL, Omoruyi FO, Simon OR, Morrison EY, Asemota HN(PubMed)

Phytochemical Piperine and Angiogenesis

Piperine is a phytochemical alkaloid in the class of organosulfur compound, found abundantly in white and black pepper, long pepper, etc.
Angiogenesis is the form of new blood vessels in the body for healing and reproduction.
The benefits
Piperine, a major alkaloid constituent of black pepper, exerted it anti angiogenic effect to cause apoptosis in some cancer cell lines such as in inhibited the proliferation and G(1)/S transition of human umbilical vein endothelial cells (HUVECs) without causing cell death, as well as collagen-induced angiogenic activity by rat aorta explants and breast cancer cell-induced angiogenesis in chick embryos. Piperine in the co administration with curcumin, enhancing the functions of curcumin in suppression of many diseases including angiogenesis.


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Phytochemical Therapy http://kylejnorton.blogspot.ca/p/phytochemical-therapy.html


References
(1) Piperine, a dietary phytochemical, inhibits angiogenesis by Doucette CD, Hilchie AL, Liwski R, Hoskin DW.(PubMed)
(2) Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature by Anand P, Thomas SG, Kunnumakkara AB, Sundaram C, Harikumar KB, Sung B, Tharakan ST, Misra K, Priyadarsini IK, Rajasekharan KN, Aggarwal BB.(PubMed)