Kyle J. Norton
Scientists may have found a bioactive ingredient for the prevention and treatment of neurodegeneration with no side effects, according to studies.
Probiotics are live bacteria and yeasts that play an essential role in the improvement of digestive functioning.
In other words, probiotics balanced the ratio of the gut microbiota by improving the levels of healthy organisms in the gut, particularly in people who are taking antibiotics, leading to the optimization of the digestive system in the absorption of nutrients for the body's needs such as supplying essential nutrients, synthesizing vitamin K, aiding in the digestion of cellulose, and promoting angiogenesis and enteric nerve function.
Where gut microbiota is the complex community of microorganisms that live in our gastrointestinal tracts.
Microbial imbalance or dysbiosis-induced intestinal inflammation as a result of overexpression of bad organisms in the gut has been found to utilize a complex arsenal of virulence factors to colonize and persist in the intestine, implicating the development of intestinal diseases.
Some virulence factors such as the genotoxin colibactin, produced by overexpression of bad bacteria in the gut were found to promote colorectal cancer and chronic intestinal inflammatory diseases.
Dr. Yu-Jie Zhang, the lead scientist in the examined the importance of gut bacteria on Human Health wrote, "Gut bacteria are an important component of the microbiota ecosystem in the human gut, which is colonized by 1014 microbes, ten times more than the human cells".
And, " they (imbalanced ratio of gut microbiota) can also be potentially harmful due to the change of their composition when the gut ecosystem undergoes abnormal changes in the light of the use of antibiotics, illness, stress, aging, bad dietary habits, and lifestyle. Dysbiosis of the gut bacteria communities can cause many chronic diseases, such as inflammatory bowel disease, obesity, cancer, and autism".
The cucumber plant is a species of Cucumis Sativus, belongs to the family Cucurbitaceae, and is native to Western Asia. It is a creeping vine with roots in the ground and grows up with the support of frames.
With an aim to find potential and natural compounds for the improvement of digestive health, researchers investigation the probiotic activity of cucumber.
According to the novel strain of lactic acid bacterium isolated from fermented cucumber, fermented carbohydrates such as sucrose, dextrose, and arabinose showed a significant gastroprotective effect against antibiotics, including ciprofloxacin, kanamycin, and vancomycin.
Furthermore, the isolate displayed potential probiotic properties in the improvement of the digestive health observed by hydrophobicity, autoaggregation, coaggregation, and in vitro cell adhesion ability.
Moreover, the isolate also exhibited resistance against bad bacteria and simulated gastric juice at pH 3.0.
Based on the findings researchers suggested that a novel strain of lactic acid bacterium isolated from fermented cucumber protected the digestive tract against the injection of antibiotics, inhibited the production of bad bacteria such as gram-positive bacterial and utilized the effects of prebiotics such as inulin and raffinose.
Dr. Shukla R, the lead scientist said, " These results indicate both probiotic property and the glucan-sucrase-producing ability of P. pentosaceus CRAG3".
In vitro, in the evaluation of the probiotic potentials of three Bacillus strains 437F, 1630F, and 1020G obtained from the traditional pickle researchers found that
* All strains only showed high acid, and bile tolerance but also exhibited antagonistic activity against various pathogens.
* All strains exhibited antioxidant activity, auto- and co-aggregation ability and surface hydrophobicity and attachment capacity against the Caco-2 cells were similar to those of well-known probiotic strains.
* All strains are safe without causing harm to healthy colon cells.
Based on the findings, researchers said, "With respect to their characteristics and safety aspect, these Bacillus species may have the potential to consider as probiotics for animal and/or human applications".
Taken altogether, cucumber may be considered supplements for the protection of digestive functioning, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Probiotic Potential of Pediococcus pentosaceus CRAG3: A New Isolate from Fermented Cucumber by Shukla R1, Goyal A. (PubMed)
(2) Three novel Bacillus strains from a traditional lacto-fermented pickle as potential probiotics by Talebi S1, Makhdoumi A1, Bahreini M1, Matin MM1,2, Moradi HS. (PubMed)
(3) Impacts of Gut Bacteria on Human Health and Diseases by Yu-Jie Zhang,1 Sha Li,2 Ren-You Gan,3 Tong Zhou,1 Dong-Ping Xu,1 and Hua-Bin Li1. (PubMed)
Thursday, 17 August 2023
#Phytochemical #Lycopene Protects the Bone Density Against the Onset of Osteoporopsis, Researchers Find
Kyle J. Norton
The osteoclast is a type of cell differentiated from another type of cell called a macrophage that breaks down the bone which leads to bone resorption.
In patients with osteoporosis, this balance shifts in favor of osteoclasts compared to those of osteoblasts.
In other words, in osteoporotic patients, bone resorption is far more exceedingly to bone formation.
Furthermore, the imbalance of osteoclasts and osteoblasts also is found in patients with Paget's disease, rheumatoid arthritis, osteopetrosis, periodontal disease, and bone cancer metastases.
Osteoclastogenesis is a procedure that included many stages, that interferes with the specific stage of the process, diseases associated with imbalanced osteoclasts, and osteoblast that may be preventable in the future.
Dr. Tobias Braun wrote, "Bone loss in RA patients is a frequent and clinically serious event. Considering bone remodeling in general, the balance between bone formation and bone resorption determines the net effect. In the past decade, significant gains in knowledge about the role of bone resorption during chronic erosive arthritis have been made. There is good evidence that inflammation itself triggers bone resorption by osteoclasts ".
And, "Pro-inflammatory cytokines are potent mediators of bone loss. These cytokines act both, directly and indirectly, to enhance osteoclastogenesis in the inflamed joint and systemic bone: first, many pro-inflammatory cytokines can alter the RANKL/OPG ratio in mesenchymal cells, such as osteoblasts and fibroblasts; second, some cytokines, such as M-CSF and RANKL, also directly affect osteoclast differentiation, survival, and activity".
Lycopene is a phytochemical in the class of carotenoids, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,
Tomatoes provide about 80% of the lycopene in the world's diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.
With an aim to find a potential phytochemical to protect bone density, researchers examined the osteoclastogenetic effect of lycopene.
According to the tested differentiation
* The ingestion of lycopene-containing products such as tomato showed a significant effect on decreased osteoclast differentiation. In other words, lycopene protected bone density by inhibiting bone reabsorption.
* Lycopene not only did not affect cell density/survival but also protected the bone by decreasing the calcium-phosphate resorption.
* Lycopene also acted as an MEK signaling inhibitor to promote bone formation.
* Additionally, lycopene also promoted an anabolic state of bone metabolism, through the regulation of the protein kinase C pathway associated with osteoclast formation and function potentially.
Based on the findings, lycopene protects bone mineral density by inhibiting the expression of osteoclastogenesis.
Researchers after taking into account co and confounders said, "This information might be relevant for the prevention and delay in the progression of osteolytic bone conditions".
Taken together, lycopene found in tomatoes may be considered supplements for the promotion of osteoclastogenesis, pending the confirmation of the larger sample size and multicenter human study.
Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Modulation of human osteoclastogenesis and osteoblastogenesis by lycopene by Costa-Rodrigues J1, Fernandes MH2, Pinho O3, Monteiro PRR. (PubMed)
(2) Lycopene treatment against loss of bone mass, microarchitecture, and strength in relation to regulatory mechanisms in a postmenopausal osteoporosis model by Ardawi MM1, Badawoud MH2, Hassan SM2, Rouzi AA3, Ardawi JMS4, AlNosani NM4, Qari MH5, Mousa SA6. (PubMed)
(3) Positive regulators of osteoclastogenesis and bone resorption in rheumatoid arthritis by Tobias Braun1 and Jochen Zwerina. (PMC)
The osteoclast is a type of cell differentiated from another type of cell called a macrophage that breaks down the bone which leads to bone resorption.
In patients with osteoporosis, this balance shifts in favor of osteoclasts compared to those of osteoblasts.
In other words, in osteoporotic patients, bone resorption is far more exceedingly to bone formation.
Furthermore, the imbalance of osteoclasts and osteoblasts also is found in patients with Paget's disease, rheumatoid arthritis, osteopetrosis, periodontal disease, and bone cancer metastases.
Osteoclastogenesis is a procedure that included many stages, that interferes with the specific stage of the process, diseases associated with imbalanced osteoclasts, and osteoblast that may be preventable in the future.
Dr. Tobias Braun wrote, "Bone loss in RA patients is a frequent and clinically serious event. Considering bone remodeling in general, the balance between bone formation and bone resorption determines the net effect. In the past decade, significant gains in knowledge about the role of bone resorption during chronic erosive arthritis have been made. There is good evidence that inflammation itself triggers bone resorption by osteoclasts ".
And, "Pro-inflammatory cytokines are potent mediators of bone loss. These cytokines act both, directly and indirectly, to enhance osteoclastogenesis in the inflamed joint and systemic bone: first, many pro-inflammatory cytokines can alter the RANKL/OPG ratio in mesenchymal cells, such as osteoblasts and fibroblasts; second, some cytokines, such as M-CSF and RANKL, also directly affect osteoclast differentiation, survival, and activity".
Lycopene is a phytochemical in the class of carotenoids, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,
Tomatoes provide about 80% of the lycopene in the world's diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.
With an aim to find a potential phytochemical to protect bone density, researchers examined the osteoclastogenetic effect of lycopene.
According to the tested differentiation
* The ingestion of lycopene-containing products such as tomato showed a significant effect on decreased osteoclast differentiation. In other words, lycopene protected bone density by inhibiting bone reabsorption.
* Lycopene not only did not affect cell density/survival but also protected the bone by decreasing the calcium-phosphate resorption.
* Lycopene also acted as an MEK signaling inhibitor to promote bone formation.
* Additionally, lycopene also promoted an anabolic state of bone metabolism, through the regulation of the protein kinase C pathway associated with osteoclast formation and function potentially.
Based on the findings, lycopene protects bone mineral density by inhibiting the expression of osteoclastogenesis.
Researchers after taking into account co and confounders said, "This information might be relevant for the prevention and delay in the progression of osteolytic bone conditions".
Taken together, lycopene found in tomatoes may be considered supplements for the promotion of osteoclastogenesis, pending the confirmation of the larger sample size and multicenter human study.
Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Modulation of human osteoclastogenesis and osteoblastogenesis by lycopene by Costa-Rodrigues J1, Fernandes MH2, Pinho O3, Monteiro PRR. (PubMed)
(2) Lycopene treatment against loss of bone mass, microarchitecture, and strength in relation to regulatory mechanisms in a postmenopausal osteoporosis model by Ardawi MM1, Badawoud MH2, Hassan SM2, Rouzi AA3, Ardawi JMS4, AlNosani NM4, Qari MH5, Mousa SA6. (PubMed)
(3) Positive regulators of osteoclastogenesis and bone resorption in rheumatoid arthritis by Tobias Braun1 and Jochen Zwerina. (PMC)
#Navy Bean Inhibits Parameters Associated with a Reduced Risk of #CardiovascularDisease, Researchers Find
Kyle J. Norton
Cardiovascular disease (CVD) is a class of diseases involved in the heart or blood vessels. In other words, CVD includes heart disease and stroke.
Heart Disease is a medical condition associated with reduced function of the heart in pumping blood to the body through its blood vessels.
In the US, heart disease causes the death of approximately 610,000 Americans every year. More precisely 1 in every 4 deaths in the US is associated with heart disease.
Most cases of heart disease are caused by high blood pressure that contributes to the hardening of the arteries, and high levels of bad cholesterol (LDL) that cause the build-up of plaque in the arteries.
High levels of bad cholesterol (LDL) have been found epidemiologically, associated with an uncontrolled diet with high levels of saturated fat and trans fat, which lead to the formation of atherosclerosis lesions and eventually arterial blockage.
In other words, anything that serves to damage the inner lining of blood vessels and impedes the transportation of oxygen and nutrition to the heart is a risk of heart disease.
A stroke is caused by the interruption or reduction of blood supply to part of the brain that deprives the brain tissue of oxygen and nutrients, leading to the death of brain cells.
According to the statistics, every year, more than 795,000 people in the US have a stroke, including 610,000 cases of new strokes.
Believe it or not, 1 of 4 cases of stroke are in people who have had a previous stroke.
There are similar causes of stroke and heart disease, but in stroke, the result is more severe. Any delay in rescuing will result in the death of the victim.
The small, white navy bean, also called pea bean or haricot, popular in both dry and green forms, is very popular in Britain and the US, native to Peru. The legume is now grown and consumed across the world, due to its numerous health benefits.
With an aim to find a potential ingredient for the prevention and treatment of cardiovascular disease, researchers examined the navy beans and rice bran effect on regulating blood lipids in adults and children.
The pilot, randomized-controlled, clinical trial included 38 children (10 ± 0.8 years old) with abnormal cholesterol who consumed a snack for 4 weeks containing either: no navy bean or rice bran (control); 17.5 g/day cooked navy bean powder; 15 g/day heat-stabilized rice bran; or 9 g/day navy beans and 8 g/day rice bran.
According to the analysis of the plasma metabolites extracted, navy bean and/or rice bran consumption influenced 71 plasma compounds compared to the control (p ≤ 0.05), with lipids representing 46% of the total plasma metabolome.
In other words, navy bean intake causes significant changes of 18 plasma lipids compared to only 10 plasma lipids for the rice bran group and 48 lipids compared to only 40 in the rice bran group compared to baseline.
More precisely, the intake of navy beans had a positive impact on blood lipid metabolism in reducing CVD risk in children.
Additional differentiation of the navy bean anti hyper cholesterol activity, researchers found that the efficacy of navy bean was attributed to the decrease of free fatty acids associated with metabolic diseases (palmitate and arachidonate) and an increase of the relative abundance of endogenous anti-inflammatory lipids.
Based on the results, researchers said, " Findings from this pilot study support the need for investigating the effects of these foods for longer durations to reduce CVD risk".
Taken together, the navy bean may be considered a remedy for the prevention and treatment of cardiovascular disease caused by high blood cholesterol, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Navy Bean and Rice Bran Intake Alters the Plasma Metabolome of Children at Risk for Cardiovascular Disease by Li KJ1, Borresen EC1, Jenkins-Puccetti N2, Luckasen G2, Ryan EP. (PubMed)
(2) Heart Diseases- Causes, Symptoms, Types, Preventions & Treatments by Kyle J. Norton
(3) Stroke -- The Causes by Kyle J. Norton
Cardiovascular disease (CVD) is a class of diseases involved in the heart or blood vessels. In other words, CVD includes heart disease and stroke.
Heart Disease is a medical condition associated with reduced function of the heart in pumping blood to the body through its blood vessels.
In the US, heart disease causes the death of approximately 610,000 Americans every year. More precisely 1 in every 4 deaths in the US is associated with heart disease.
Most cases of heart disease are caused by high blood pressure that contributes to the hardening of the arteries, and high levels of bad cholesterol (LDL) that cause the build-up of plaque in the arteries.
High levels of bad cholesterol (LDL) have been found epidemiologically, associated with an uncontrolled diet with high levels of saturated fat and trans fat, which lead to the formation of atherosclerosis lesions and eventually arterial blockage.
In other words, anything that serves to damage the inner lining of blood vessels and impedes the transportation of oxygen and nutrition to the heart is a risk of heart disease.
A stroke is caused by the interruption or reduction of blood supply to part of the brain that deprives the brain tissue of oxygen and nutrients, leading to the death of brain cells.
According to the statistics, every year, more than 795,000 people in the US have a stroke, including 610,000 cases of new strokes.
Believe it or not, 1 of 4 cases of stroke are in people who have had a previous stroke.
There are similar causes of stroke and heart disease, but in stroke, the result is more severe. Any delay in rescuing will result in the death of the victim.
The small, white navy bean, also called pea bean or haricot, popular in both dry and green forms, is very popular in Britain and the US, native to Peru. The legume is now grown and consumed across the world, due to its numerous health benefits.
With an aim to find a potential ingredient for the prevention and treatment of cardiovascular disease, researchers examined the navy beans and rice bran effect on regulating blood lipids in adults and children.
The pilot, randomized-controlled, clinical trial included 38 children (10 ± 0.8 years old) with abnormal cholesterol who consumed a snack for 4 weeks containing either: no navy bean or rice bran (control); 17.5 g/day cooked navy bean powder; 15 g/day heat-stabilized rice bran; or 9 g/day navy beans and 8 g/day rice bran.
According to the analysis of the plasma metabolites extracted, navy bean and/or rice bran consumption influenced 71 plasma compounds compared to the control (p ≤ 0.05), with lipids representing 46% of the total plasma metabolome.
In other words, navy bean intake causes significant changes of 18 plasma lipids compared to only 10 plasma lipids for the rice bran group and 48 lipids compared to only 40 in the rice bran group compared to baseline.
More precisely, the intake of navy beans had a positive impact on blood lipid metabolism in reducing CVD risk in children.
Additional differentiation of the navy bean anti hyper cholesterol activity, researchers found that the efficacy of navy bean was attributed to the decrease of free fatty acids associated with metabolic diseases (palmitate and arachidonate) and an increase of the relative abundance of endogenous anti-inflammatory lipids.
Based on the results, researchers said, " Findings from this pilot study support the need for investigating the effects of these foods for longer durations to reduce CVD risk".
Taken together, the navy bean may be considered a remedy for the prevention and treatment of cardiovascular disease caused by high blood cholesterol, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Navy Bean and Rice Bran Intake Alters the Plasma Metabolome of Children at Risk for Cardiovascular Disease by Li KJ1, Borresen EC1, Jenkins-Puccetti N2, Luckasen G2, Ryan EP. (PubMed)
(2) Heart Diseases- Causes, Symptoms, Types, Preventions & Treatments by Kyle J. Norton
(3) Stroke -- The Causes by Kyle J. Norton
#Beet Inhibits Lipid Peroxidation Associated with a Reduced Risk of #Parkinson's Disease(PD), Researchers Show
Kyle J. Norton
Beet or beetroot may be considered as a functional food for reduced risk of early-onset and treatment of Parkinson's disease(PD), a recent study suggested.
Parkinson's disease (PD) is a condition of neurodegenerative disease that progressed over time caused by dysfunction of nerve cells involving motor functioning, including signs of tremor of the hands, arms, legs, jaw, and face. bradykinesia ......
Beet, best known as the beetroot or garden beet and belonging to the amaranth family, is a perennial plant with leafy stems growing to 1–2 m tall.
According to the MVP Samaj's College of Pharmacy, in the animal model of PD induced by administration of reserpine (5 mg/kg/day, i.p for 5 consecutive days), haloperidol (1 mg/kg, i.p.), and tacrine (2.5 mg/kg, i.p.), rats fed with methanolic extract of Beta vulgaris (MEBV)at doses of 100, 200, and 300 mg/kg showed a significantly reduced the intensity of muscular rigidity, duration of catalepsy, akinesia, the number of tremors, dis-proportionally.
Concentrations of 200, and 300 mg/kg extract exhibited the most effects compared to dose of 100mg/kg.
Furthermore, at the higher doses, treatment animals also exerted an improvement in locomotor functioning and grip strength analyzed by MEBV.
The study also indicated that the efficacy of beet methanolic extract may be attributed to the increase of antioxidants in inhibiting the production of lipid peroxidation, an important process in causing cell dysfunction in PD patients.
Not only that, but injection of the extract also restored the defensive antioxidant enzymes SOD and CAT in the rat brain.
Dr. The lead author said, "The mechanism of protection may be due to augmentation of cellular antioxidants".
Other researchers also suggested that intake of beet juice may improve the blood circulation of the brain's white matter of the frontal lobes associated with the development of dementia and other cognitive conditions, including the risk of PD and PD progression in older adults.
Dr. Gary Miller,, the lead author of this study said, "I think these results are consistent and encouraging - that a good diet consisting of a lot of fruits and vegetables can contribute to overall good health".
Collectively, the evidence suggested that beet methanolic extract or nitrate-rich beet juice may have a profound effect on the reduced prevalence of early-onset and progression of Parkinson's disease (PD) and may be considered a functional food. for these purposes.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Sources
(1) Neuroprotective potential of Beta vulgaris L. in Parkinson's disease by Nade VS1, Kawale LA1, Zambre SS1, Kapure AB1.(PubMed)
(2) Daily Dose Of Beet Juice Promotes Brain Health In Older Adults
Published Thursday 4 November 2010 By Janet Epping(Medical news today)
Beet or beetroot may be considered as a functional food for reduced risk of early-onset and treatment of Parkinson's disease(PD), a recent study suggested.
Parkinson's disease (PD) is a condition of neurodegenerative disease that progressed over time caused by dysfunction of nerve cells involving motor functioning, including signs of tremor of the hands, arms, legs, jaw, and face. bradykinesia ......
Beet, best known as the beetroot or garden beet and belonging to the amaranth family, is a perennial plant with leafy stems growing to 1–2 m tall.
According to the MVP Samaj's College of Pharmacy, in the animal model of PD induced by administration of reserpine (5 mg/kg/day, i.p for 5 consecutive days), haloperidol (1 mg/kg, i.p.), and tacrine (2.5 mg/kg, i.p.), rats fed with methanolic extract of Beta vulgaris (MEBV)at doses of 100, 200, and 300 mg/kg showed a significantly reduced the intensity of muscular rigidity, duration of catalepsy, akinesia, the number of tremors, dis-proportionally.
Concentrations of 200, and 300 mg/kg extract exhibited the most effects compared to dose of 100mg/kg.
Furthermore, at the higher doses, treatment animals also exerted an improvement in locomotor functioning and grip strength analyzed by MEBV.
The study also indicated that the efficacy of beet methanolic extract may be attributed to the increase of antioxidants in inhibiting the production of lipid peroxidation, an important process in causing cell dysfunction in PD patients.
Not only that, but injection of the extract also restored the defensive antioxidant enzymes SOD and CAT in the rat brain.
Dr. The lead author said, "The mechanism of protection may be due to augmentation of cellular antioxidants".
Other researchers also suggested that intake of beet juice may improve the blood circulation of the brain's white matter of the frontal lobes associated with the development of dementia and other cognitive conditions, including the risk of PD and PD progression in older adults.
Dr. Gary Miller,, the lead author of this study said, "I think these results are consistent and encouraging - that a good diet consisting of a lot of fruits and vegetables can contribute to overall good health".
Collectively, the evidence suggested that beet methanolic extract or nitrate-rich beet juice may have a profound effect on the reduced prevalence of early-onset and progression of Parkinson's disease (PD) and may be considered a functional food. for these purposes.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Sources
(1) Neuroprotective potential of Beta vulgaris L. in Parkinson's disease by Nade VS1, Kawale LA1, Zambre SS1, Kapure AB1.(PubMed)
(2) Daily Dose Of Beet Juice Promotes Brain Health In Older Adults
Published Thursday 4 November 2010 By Janet Epping(Medical news today)
#CommonPeas Stimulate Immunomodulating Expression Associated with Injury and Infection, Researchers Say
Kyle J. Norton
Intake of common (dried) peas daily and regularly may have a potential effect in enhanced immunomodulating activity, scientists at some renowned institute studies suggested.
The dried pea is a small but nutritionally mighty member of the legume family, genus Pisum belongings to the family Fabaceae with a healthy source of proteins, fibers, vitamins, and minerals.
Immunomodulation is an action with a profound and positive effect on regulated immune response and function through the activation of antibody formation or the inhibition of white blood cell activity.
In the evaluation of 173 LAB strains, including the strain NTM048 isolated from green peas having the ability to induce IgA production using murine Peyer's patch cells, researchers at the Ishikawa Prefectural University, after taking account of other confounders suggested that
1. Strain NTM048 isolated from green peas demonstrated a higher immunomodulating activity in compared to other straits.
2. The green pea strait also is well tolerated in gastrointestinal digestion and produces large amounts of exopolysaccharides, high-molecular-weight polymers that have been used in conventional medicine for the prospect of anticoagulant, antithrombotic, immunomodulation, anticancer and as flocculants.
3. Application of the strait also induced a significant increase in the fecal IgA content and plasma IgA levels in response to the immunogen of BALB/cA mice
Further analysis of the function of the strait isolated from green pea, researchers emphasized that the strait has a significant impact in stimulating immunomodulating activities through regulating the transforming growth factor-β in the secretion of inflammatory cytokines which play an important role in the control of cell growth, cell proliferation, cell differentiation, and apoptosis.
The action of the strait in the activation of immunomodulating activity was also attributed to stimulating Peyer's patch cells which are aggregated in lymphoid nodules, and formed an important part of the immune system.
The information findings prompted Dr. Matsuzaki C, the lead author to suggest, "Strain NTM048 stimulates Peyer's patch cells to induce an intestinal and systemic immune response, revealing the potential of NTM048 as a probiotic for enhancing the mucosal barrier function".
The collective information of NTM048 as a probiotic may be helpful to reduce symptoms and treatments of people with digestive disorders by including portions of green peas or dried peas in their daily diet.
Additionally, in another field of study, researchers at the University of Ottawa launched an investigation of the immunomodulating activity of enzymatic protein hydrolysates of yellow peas using in a murine model indicating that
1. Oral administration of Pea protein hydrolysate, after a 12 h pre-treatment, showed significant inhibition of free radical NO production by activating increased mobile white blood cells by 20%.
The reduction of ROS may be a result of overexpression of antioxidant production in stimulated immunomodulating effect to protect against localized tissue and injure against infection and inflammation caused by foreign pathogens.
2. The injection also showed a strongly inhibited secretion of pro-inflammatory cytokines, TNF-α- and IL-6, in a range of 35 and 80%, respectively.
TNF-α, Tumor necrosis factor is a protein with function in initiated response in the acute phase of inflammation
IL-6 (Interleukin 6) secreted by the immune system to stimulate an immune response, is an interleukin with duo functions in promoting either pro and anti-inflammatory cytokines respectively.
The inhibition of the pro-inflammatory substance of the pea protein may have a potential effect in reduced symptoms and complications such as reddened, swollen, hot, and often painful in the location of injury or infection.
3. The protein also stimulated the gut mucosal immune response.
The gut mucosal immune response against harmful intestinal organisms has a strong impact in reducing the risk of digestive disorder, by regulating the function of lymphoid tissue located in the mucosa.
According to the article on mucosal immunology, "the mucosal immune system provides protection against pathogens but maintains a tolerance towards non-harmful commensal microbes and benign environmental substances".
4. The immunomodulating effect is also found in an increased number of IgA+ cells in the small intestine lamina propria accompanied by an increase in the number of IL-4+, IL-10+, and IFN-γ+ cells.
In this case, the immunomodulating effect through the expression of the production of IgA+ cells in
protected the intestine lamina propria(based membrane) from pathogens, toxins, and food antigens the basement remembrance of the intestine by increasing the numbers of interleukin IL-4+, and IL-10+ in inhibiting the production of pro-inflammatory cytokines as well as the increased function of IFN-γ+ cells in stimulated innate and adaptive immunity against viral, some bacterial and protozoal infections.
Further differentiation also suggested that the enhanced IL-6 secretion of small intestine epithelial cells (IEC) by the Pea protein hydrolysate in stimulation IgA-secretion, probably associated with a number of mechanisms, particularly in TLR2 and TLR4 function in pathogen recognition and activation of innate immunity.
Taken together, green peas or common peas may be considered as a therapeutic treatment in enhanced immunomodulating activity, particularly in aging adults and people with a history of weakened immunity.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, healthblogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.
Sources
(1) Immunomodulating activity of exopolysaccharide-producing Leuconostoc mesenteroides strain NTM048 from green peas by Matsuzaki C1, Kamishima K, Matsumoto K, Koga H, Katayama T, Yamamoto K, Hisa K.(PubMed)
(2)Anti-oxidant, anti-inflammatory and immunomodulating properties of an enzymatic protein hydrolysate from yellow field pea seeds by Ndiaye F1, Vuong T, Duarte J, Aluko RE, Matar C.(PubMed)
(3) Mucosal immunology by Nature.com
Intake of common (dried) peas daily and regularly may have a potential effect in enhanced immunomodulating activity, scientists at some renowned institute studies suggested.
The dried pea is a small but nutritionally mighty member of the legume family, genus Pisum belongings to the family Fabaceae with a healthy source of proteins, fibers, vitamins, and minerals.
Immunomodulation is an action with a profound and positive effect on regulated immune response and function through the activation of antibody formation or the inhibition of white blood cell activity.
In the evaluation of 173 LAB strains, including the strain NTM048 isolated from green peas having the ability to induce IgA production using murine Peyer's patch cells, researchers at the Ishikawa Prefectural University, after taking account of other confounders suggested that
1. Strain NTM048 isolated from green peas demonstrated a higher immunomodulating activity in compared to other straits.
2. The green pea strait also is well tolerated in gastrointestinal digestion and produces large amounts of exopolysaccharides, high-molecular-weight polymers that have been used in conventional medicine for the prospect of anticoagulant, antithrombotic, immunomodulation, anticancer and as flocculants.
3. Application of the strait also induced a significant increase in the fecal IgA content and plasma IgA levels in response to the immunogen of BALB/cA mice
Further analysis of the function of the strait isolated from green pea, researchers emphasized that the strait has a significant impact in stimulating immunomodulating activities through regulating the transforming growth factor-β in the secretion of inflammatory cytokines which play an important role in the control of cell growth, cell proliferation, cell differentiation, and apoptosis.
The action of the strait in the activation of immunomodulating activity was also attributed to stimulating Peyer's patch cells which are aggregated in lymphoid nodules, and formed an important part of the immune system.
The information findings prompted Dr. Matsuzaki C, the lead author to suggest, "Strain NTM048 stimulates Peyer's patch cells to induce an intestinal and systemic immune response, revealing the potential of NTM048 as a probiotic for enhancing the mucosal barrier function".
The collective information of NTM048 as a probiotic may be helpful to reduce symptoms and treatments of people with digestive disorders by including portions of green peas or dried peas in their daily diet.
Additionally, in another field of study, researchers at the University of Ottawa launched an investigation of the immunomodulating activity of enzymatic protein hydrolysates of yellow peas using in a murine model indicating that
1. Oral administration of Pea protein hydrolysate, after a 12 h pre-treatment, showed significant inhibition of free radical NO production by activating increased mobile white blood cells by 20%.
The reduction of ROS may be a result of overexpression of antioxidant production in stimulated immunomodulating effect to protect against localized tissue and injure against infection and inflammation caused by foreign pathogens.
2. The injection also showed a strongly inhibited secretion of pro-inflammatory cytokines, TNF-α- and IL-6, in a range of 35 and 80%, respectively.
TNF-α, Tumor necrosis factor is a protein with function in initiated response in the acute phase of inflammation
IL-6 (Interleukin 6) secreted by the immune system to stimulate an immune response, is an interleukin with duo functions in promoting either pro and anti-inflammatory cytokines respectively.
The inhibition of the pro-inflammatory substance of the pea protein may have a potential effect in reduced symptoms and complications such as reddened, swollen, hot, and often painful in the location of injury or infection.
3. The protein also stimulated the gut mucosal immune response.
The gut mucosal immune response against harmful intestinal organisms has a strong impact in reducing the risk of digestive disorder, by regulating the function of lymphoid tissue located in the mucosa.
According to the article on mucosal immunology, "the mucosal immune system provides protection against pathogens but maintains a tolerance towards non-harmful commensal microbes and benign environmental substances".
4. The immunomodulating effect is also found in an increased number of IgA+ cells in the small intestine lamina propria accompanied by an increase in the number of IL-4+, IL-10+, and IFN-γ+ cells.
In this case, the immunomodulating effect through the expression of the production of IgA+ cells in
protected the intestine lamina propria(based membrane) from pathogens, toxins, and food antigens the basement remembrance of the intestine by increasing the numbers of interleukin IL-4+, and IL-10+ in inhibiting the production of pro-inflammatory cytokines as well as the increased function of IFN-γ+ cells in stimulated innate and adaptive immunity against viral, some bacterial and protozoal infections.
Further differentiation also suggested that the enhanced IL-6 secretion of small intestine epithelial cells (IEC) by the Pea protein hydrolysate in stimulation IgA-secretion, probably associated with a number of mechanisms, particularly in TLR2 and TLR4 function in pathogen recognition and activation of innate immunity.
Taken together, green peas or common peas may be considered as a therapeutic treatment in enhanced immunomodulating activity, particularly in aging adults and people with a history of weakened immunity.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, healthblogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.
Sources
(1) Immunomodulating activity of exopolysaccharide-producing Leuconostoc mesenteroides strain NTM048 from green peas by Matsuzaki C1, Kamishima K, Matsumoto K, Koga H, Katayama T, Yamamoto K, Hisa K.(PubMed)
(2)Anti-oxidant, anti-inflammatory and immunomodulating properties of an enzymatic protein hydrolysate from yellow field pea seeds by Ndiaye F1, Vuong T, Duarte J, Aluko RE, Matar C.(PubMed)
(3) Mucosal immunology by Nature.com
#CruciferousVegetables Lower the risk of Cardiovascular Disease and Cancer and Improve Public Health, Researchers Say
A recent study conducted by the University of Lund, fermented Brussels sprouts, one of the members of cruciferous vegetables bound the secretion of bile acids from the liver by increased 25% of the fecal dry weight.
The study also confirmed that in various vegetables (carrots, rutabagas, peas, green beans, and Brussels sprouts), the total excretion of bile acids was reduced only when Brussels sprouts were added.
Cruciferous vegetables are a group of vegetables belonging to the family Brassicaceae, including cauliflower, cabbage, cress, bok choy, broccoli, etc.
Bile acids secreted by the liver with purpose in removing excess cholesterol in the body and aiding intestinal digestion.
Binding bile acids in the gastrointestinal tract is the function of preventing reabsorption from the gut with an aim to lower the levels of cholesterol.
In vitro, the study of cruciferous vegetables also suggested that consumed regularly after steam cooking, would lower the risk of cardiovascular disease and cancer and improve public health, through lowered recirculation of bile acids resulting in the utilization of cholesterol to synthesize bile acid and reduced fat absorption even more.
Dr. Kahlon TS, the lead author of the study said, "Relative to cholestyramine, (a cholesterol-lowering, bile acid-binding drug) in vitro bile acid-binding on dry matter basis was for the collard greens, kale, and mustard greens, 13%; broccoli, 10%; Brussels sprouts and spinach, 8%; green bell pepper, 7%; and cabbage, 5%" and (the levels of effectiveness can be classified as follows)"collard greens = kale = mustard greens > broccoli > Brussels sprouts = spinach = green bell pepper > cabbage".
Furthermore, according to the article published in the science research, besides steam cooking showed to significantly improved bile acid-binding of green/leafy vegetables; sautéing also significantly improved bile acid-binding of mustard greens, kale, broccoli, cabbage, and green bell pepper compared with steaming, boiling or raw (uncooked).
In fact, Collard greens exhibited significantly higher bile acid binding by steaming compared with sautéing, boiling, or raw in comparison to other cruciferous vegetables.
Therefore, it is safe to insist that the intake of cruciferous vegetables regularly can lower the risk of cardiovascular disease and cancer, by lowering cholesterol absorption and reabsorption.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
References
(1) Fermentation of vegetable fiber in the intestinal tract of rats and effects on fecal bulking and bile acid excretion by Nyman M1, Schweizer TF, Tyrén S, Reimann S, Asp NG. (PubMed)
(2) Steam cooking significantly improves in vitro bile acid binding of collard greens, kale, mustard greens, broccoli, green bell pepper, and cabbage by Kaifhlon TS1, Chiu MC, Chapman MH.(PubMed)ch
(3) In Vitro Bile Acid Binding of Mustard Greens, Kale, Broccoli, Cabbage and Green Bell Pepper Improves with Sautéing Compared with Raw or Other Methods of Preparation by Talwinder S. Kahlon, Rebecca R. Milczarek, Mei-Chin M. Chiu(Scientific Research)
Consumption of Carotenoid-Rich Vegetables Improves Immunity Against the Risk of #ChronicInflammatoryDiseases, Studies Suggest
Kyle J. Norton
Carrots and tomatoes and their major bioactive carotenoids may have a profound and positive effect on boosting immunity, some scientists suggested.
The results of the studies were carried out by numbers institutes in numbers of different differentiation, including the Institute of Nutritional Physiology, Federal Research Centre for Nutrition.
You can also view the abstract by clicking the links in the resources.
Immunity is a natural defense of organisms with an aim to protect the host to resist a particular infection or toxin through an expression of antibodies or sensitized white blood cells.
Carrot, a root vegetable with orange color is a sub species of Daucus carota, belongings to the family Apiaceae, native to Asian and Europe.
Tomato is red, edible fruit, genus Solanum, belongings to family Solanaceae, native to South America.
Because of its health benefits, tomato is grown worldwide for commercial purposes and often in the greenhouse.
In the investigation of the effect of beta-carotene has been shown to enhance immune functions in humans, the Institute of Nutritional Physiology, Federal Research Centre for Nutrition launched a study to examine whether vegetables rich in carotenoids, such as beta-carotene or lycopene, exert any modulation of immune function in healthy humans.
The blinded, randomized, cross-over study, included male subjects on a low-carotenoid diet who consumed 330 ml/day of either tomato juice(37.0 mg/day lycopene) or carrot juice (27.1 mg/day beta-carotene and 13.1 mg/day alpha-carotene) for 2 weeks with a 2-week depletion period after juice intervention.
Epidemiological studies suggested that consuming carotenoids from food sources may provide a variety of health benefits including a reduced incidence of cancers, risk of cardiovascular disease, and improved eye health,.......
Reading of the immune status was assessed by measuring the related activity of natural killer (NK) cells, secretion of cytokines ( IL-2, IL-4, TNFalpha), and proliferation by activated peripheral blood mononuclear cells((T cells, B cells, NK cells).
Natural killer cells are a type of white blood cells formed as a component of the innate immune system with function in inhibited microorganisms infected cells.
Interleukin-2 (IL-2) is a type of inflammatory cytokine with a function in a signaling molecule in the immune system to protect the body against bacterial and viral in the acute phase of infection.
Interleukin-4 (IL-4) is activated by lymphoid cells in the inflammatory cytokine critical for initiating humoral immunity against extracellular pathogens.
Both Interleukin-2 and 4 (IL-2 and 4 ) play an important role in chronic inflammation and wound repair.
Tumor necrosis factor (TNF) including, tumor necrosis factor-alpha, TNFα, cachexin, or cachectin) is a protein (cytokine) involved in systemic inflammation during the acute phase of infection?
At the end of the experiment, researchers found that
* Both juices treated participants demonstrate relatively fast responses in plasma carotenoid concentrations (p < 0.0002) without inducing concomitant changes in immune functions.
* Intake of both tomato and carrot juice displays a significant activity of immunity in the production of IL-2, NK cell cytotoxicity, and lymphocyte proliferation with maximum responses observed during depletion periods.
* Compared to the secretion of other inflammatory cytokines, TNF alpha exerts only at the end of the first intervention period.
* During the course of innervation, both juices show insignificant effects in modulating the secretion of IL-4.
These results suggested that lower plasma carotenoid concentrations in the bloodstream may reduce the immune function in response to diseases caused by bacterial and viral infection, particularly in the acute phase.
Occasional intake of tomato and carrot juice does not enhance body immunity, due to its function in time-delayed modulation of immune functions and its degradation caused by a number of factors, including heat, light, oxygen, acid, transition metal, or interactions with radical species.
The conclusion truly addressed the importance of carotenoids in modulated immune response in the protection of bodily injury or damage during the acute phase of infection through inhibiting pro-inflammatory overexpression in the induction of cytotoxicity and damage to nearby healthy cells.
Further to reaffirm the effects of the consumption of carotenoid-rich vegetables on the immune system, the Institute of Nutritional Physiology, Federal Research Centre for Nutrition conducted a study of 23 non-smokers, male subjects, who were not restricted in their daily diet, except that they had to abstain from fruit and vegetables high in carotenoids throughout the whole study period with blood collected weekly from subjects after a 12 h fast.
The study was also divided into four periods, each lasting 2 weeks: * Weeks 1-2: low-carotenoid period;
* Daily consumption of 330 ml tomato juice (40 mg lycopene/d, 1.5 mg beta-carotene/d) (weeks 3-4),
* 330 ml carrot juice (21.6 mg beta-carotene/d, 15.7 mg alpha-carotene/d, 0.5 mg lutein/d) (weeks 5-6)
* 10 g dried spinach powder (11.3 mg lutein/d, 3.1 mg beta-carotene/d) (weeks 7-8).
According to the assessment of T-lymphocyte and secretion of immunoreactive cytokines, lower concentration due to consumption of a low-carotenoid diet exerted a significantly reduced proliferation of function immune system observed in peripheral blood mononuclear cells (PBMC) cultured with concanavalin A.
At the end of the first 2 weeks of tomato juice consumption and until the end of the intervention period, researchers found that intake of tomato juice with abundant carotenoids induced an insignificant change in lymphocyte proliferation in compared to concentration at the end of the depletion period.
Similarly, the experiment also exerted a strong immune modulated effect in the assessment of the secretion of cytokines interleukin (IL)-2 and -4).
The dietary intervention improved the IL-2 and IL-4 secretion values. however, the levels of IL-2 and IL-4 were significantly suppressed after the low-carotenoid diet.
The results at the end of the period also expressed the similarity of other studies " After carrot juice and spinach powder consumption the cytokine secretion capacity of PBMC was not significantly different from that at the end of the depletion period".
Dr. Watzl B, the lead author after taking into account other co and confounders said, "The results of the present study indicate that a low-carotenoid diet reduces T-lymphocyte functions and the addition of tomato juice restores these functions".
The unexplained changes in the plasma carotenoid concentrations probably severed as an indication that other phytochemicals or other mechanisms in tomato and carrot juice may have a strong implication in modulated immune response other than the cytokine secretion capacity of PBMC.
Taken together, tomato and carrot juice and their bioactive carotenoids may be considered as functional foods in boosting immune function against foreign organisms, particularly, in the acute phase of infection.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.
Sources
(1) Supplementation of a low-carotenoid diet with tomato or carrot juice modulates immune functions in healthy men by Watzl B1, Bub A, Briviba K, Rechkemmer G(PubMed)
(2) Modulation of human T-lymphocyte functions by the consumption of carotenoid-rich vegetables by Watzl B1, Bub A, Brandstetter BR, Rechkemmer G.(PubMed)
(3) Factors influencing the chemical stability of carotenoids in foods by Boon CS1, McClements DJ, Weiss J, Decker EA(PubMed)
Carrots and tomatoes and their major bioactive carotenoids may have a profound and positive effect on boosting immunity, some scientists suggested.
The results of the studies were carried out by numbers institutes in numbers of different differentiation, including the Institute of Nutritional Physiology, Federal Research Centre for Nutrition.
You can also view the abstract by clicking the links in the resources.
Immunity is a natural defense of organisms with an aim to protect the host to resist a particular infection or toxin through an expression of antibodies or sensitized white blood cells.
Carrot, a root vegetable with orange color is a sub species of Daucus carota, belongings to the family Apiaceae, native to Asian and Europe.
Tomato is red, edible fruit, genus Solanum, belongings to family Solanaceae, native to South America.
Because of its health benefits, tomato is grown worldwide for commercial purposes and often in the greenhouse.
In the investigation of the effect of beta-carotene has been shown to enhance immune functions in humans, the Institute of Nutritional Physiology, Federal Research Centre for Nutrition launched a study to examine whether vegetables rich in carotenoids, such as beta-carotene or lycopene, exert any modulation of immune function in healthy humans.
The blinded, randomized, cross-over study, included male subjects on a low-carotenoid diet who consumed 330 ml/day of either tomato juice(37.0 mg/day lycopene) or carrot juice (27.1 mg/day beta-carotene and 13.1 mg/day alpha-carotene) for 2 weeks with a 2-week depletion period after juice intervention.
Epidemiological studies suggested that consuming carotenoids from food sources may provide a variety of health benefits including a reduced incidence of cancers, risk of cardiovascular disease, and improved eye health,.......
Reading of the immune status was assessed by measuring the related activity of natural killer (NK) cells, secretion of cytokines ( IL-2, IL-4, TNFalpha), and proliferation by activated peripheral blood mononuclear cells((T cells, B cells, NK cells).
Natural killer cells are a type of white blood cells formed as a component of the innate immune system with function in inhibited microorganisms infected cells.
Interleukin-2 (IL-2) is a type of inflammatory cytokine with a function in a signaling molecule in the immune system to protect the body against bacterial and viral in the acute phase of infection.
Interleukin-4 (IL-4) is activated by lymphoid cells in the inflammatory cytokine critical for initiating humoral immunity against extracellular pathogens.
Both Interleukin-2 and 4 (IL-2 and 4 ) play an important role in chronic inflammation and wound repair.
Tumor necrosis factor (TNF) including, tumor necrosis factor-alpha, TNFα, cachexin, or cachectin) is a protein (cytokine) involved in systemic inflammation during the acute phase of infection?
At the end of the experiment, researchers found that
* Both juices treated participants demonstrate relatively fast responses in plasma carotenoid concentrations (p < 0.0002) without inducing concomitant changes in immune functions.
* Intake of both tomato and carrot juice displays a significant activity of immunity in the production of IL-2, NK cell cytotoxicity, and lymphocyte proliferation with maximum responses observed during depletion periods.
* Compared to the secretion of other inflammatory cytokines, TNF alpha exerts only at the end of the first intervention period.
* During the course of innervation, both juices show insignificant effects in modulating the secretion of IL-4.
These results suggested that lower plasma carotenoid concentrations in the bloodstream may reduce the immune function in response to diseases caused by bacterial and viral infection, particularly in the acute phase.
Occasional intake of tomato and carrot juice does not enhance body immunity, due to its function in time-delayed modulation of immune functions and its degradation caused by a number of factors, including heat, light, oxygen, acid, transition metal, or interactions with radical species.
The conclusion truly addressed the importance of carotenoids in modulated immune response in the protection of bodily injury or damage during the acute phase of infection through inhibiting pro-inflammatory overexpression in the induction of cytotoxicity and damage to nearby healthy cells.
Further to reaffirm the effects of the consumption of carotenoid-rich vegetables on the immune system, the Institute of Nutritional Physiology, Federal Research Centre for Nutrition conducted a study of 23 non-smokers, male subjects, who were not restricted in their daily diet, except that they had to abstain from fruit and vegetables high in carotenoids throughout the whole study period with blood collected weekly from subjects after a 12 h fast.
The study was also divided into four periods, each lasting 2 weeks: * Weeks 1-2: low-carotenoid period;
* Daily consumption of 330 ml tomato juice (40 mg lycopene/d, 1.5 mg beta-carotene/d) (weeks 3-4),
* 330 ml carrot juice (21.6 mg beta-carotene/d, 15.7 mg alpha-carotene/d, 0.5 mg lutein/d) (weeks 5-6)
* 10 g dried spinach powder (11.3 mg lutein/d, 3.1 mg beta-carotene/d) (weeks 7-8).
According to the assessment of T-lymphocyte and secretion of immunoreactive cytokines, lower concentration due to consumption of a low-carotenoid diet exerted a significantly reduced proliferation of function immune system observed in peripheral blood mononuclear cells (PBMC) cultured with concanavalin A.
At the end of the first 2 weeks of tomato juice consumption and until the end of the intervention period, researchers found that intake of tomato juice with abundant carotenoids induced an insignificant change in lymphocyte proliferation in compared to concentration at the end of the depletion period.
Similarly, the experiment also exerted a strong immune modulated effect in the assessment of the secretion of cytokines interleukin (IL)-2 and -4).
The dietary intervention improved the IL-2 and IL-4 secretion values. however, the levels of IL-2 and IL-4 were significantly suppressed after the low-carotenoid diet.
The results at the end of the period also expressed the similarity of other studies " After carrot juice and spinach powder consumption the cytokine secretion capacity of PBMC was not significantly different from that at the end of the depletion period".
Dr. Watzl B, the lead author after taking into account other co and confounders said, "The results of the present study indicate that a low-carotenoid diet reduces T-lymphocyte functions and the addition of tomato juice restores these functions".
The unexplained changes in the plasma carotenoid concentrations probably severed as an indication that other phytochemicals or other mechanisms in tomato and carrot juice may have a strong implication in modulated immune response other than the cytokine secretion capacity of PBMC.
Taken together, tomato and carrot juice and their bioactive carotenoids may be considered as functional foods in boosting immune function against foreign organisms, particularly, in the acute phase of infection.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.
Sources
(1) Supplementation of a low-carotenoid diet with tomato or carrot juice modulates immune functions in healthy men by Watzl B1, Bub A, Briviba K, Rechkemmer G(PubMed)
(2) Modulation of human T-lymphocyte functions by the consumption of carotenoid-rich vegetables by Watzl B1, Bub A, Brandstetter BR, Rechkemmer G.(PubMed)
(3) Factors influencing the chemical stability of carotenoids in foods by Boon CS1, McClements DJ, Weiss J, Decker EA(PubMed)
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