#Herbal #Burdock Shows a Significant Effect on Infectious Diseases, According to Studies

Kyle J. Norton

Scientists may have found a herbal plant for the prevention and treatment of bacterial infection with no side effects, according to studies.
Infection is a result of the invasion of microorganisms that have successfully multiplied in the host body and the reaction of host tissues.

Bacteria is a single-cell microorganism. Most bacterias are not harmful, some may also benefit the digestive system. However, 1% of invasive bacteria can make us sick and damage the body tissue, such as bacteria associated with tuberculosis.

There are many ways to cause infection including bacteria passed from person to person, transmitted by bites from insects or animals. and ingesting contaminated food or water.

The most common symptoms of infectious diseases are fever, diarrhea, fatigue, muscle aches, and coughing, depending on the specific area of infection.

The immune system is the set of cells and their activity against antigens or infectious agents that comprises the body's defense system against diseases.

Most bacteria are killed in the first phase of acute infection. In this phase, the immune white blood cells in the first line of defense in responding to the body tissue damage or injury by stimulating the production of proinflammatory cytokines to kill off all invasive pathogens on the site of damage.

However, overexpression of proinflammatory cytokines in most cases can destroy the nearby healthy cells, leading to the formation of scars as seen in liver infection.

What contributes to the overexpression of proinflammatory and underexpression of anti-inflammatory cytokines of the body in the initiation of chronic inflammatory diseases?

Dr. Thomas W. McDade and colleagues in the investigation of the role of proinflammatory cytokines in the risk of infection explained, "The metabolic syndrome may be characterized by dysregulated inflammation, in which an important anti-inflammatory signal is absent. Similarly, in a prospective study of patients with acute coronary syndromes, baseline IL-10 concentration was a significant predictor of death or myocardial infarction during 6 months of follow-up, ......high IL-10 experienced an adverse outcome, compared to 21.8% of patients with high CRP but low IL-10

Burdock is a plant in the group of biennial thistles, genus Arctium, belonging to the family Asteraceae, native to the Euro.

The plant has been used for thousands of years in China medicine as a diuretic, diaphoretic, and blood-purifying agent and to treat wounds and infections stomach ulcers, and other digestive problems.

With an aim to discover natural bio components from plants with antibacterial activity on endodontic microbiota for the new therapies, researchers evaluated the antibacterial activity of a phytotherapeutic agent prepared from an ethyl acetate fraction (AcOEt) extracted from Arctium lappa.

A total of 27 maxillary canines with a mixed bacterial suspension of Pseudomonas aeruginosa, Escherichia coli, Lactobacillus acidophilus, Streptococcus mutans Candida albicans were included in the study.

The teeth were divided into three groups and their canals were filled with group 1, calcium hydroxide and propylene glycol; group 2, a paste containing AcOEt fraction of A. lappa (Burdock) and propylene glycol; group 3, propylene glycol (control).

At 7, 14, and 30 days, three teeth from each group opened, researchers found that mild bacterial growth was found in group 1 at all time intervals; in group 2 there was severe growth at 7 days, but no growth at 14 and 30 days.


These results indicated a significant antibacterial effect of AcOEt fraction of A. lappa in inhibiting the growth of all the microorganisms.

Furthermore, in vitro, the antimicrobial activity of rough extracts from leaves of Arctium lappa showed inhibition of Enterococcus faecalis, Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus subtilis, and Candida albicans selectively to specific target microorganisms.

In other words, each constituent in the extract of Burdock inhibited only a certain type of endodontic pathogens without affecting others.


Dr.Pereira JV, the lead author said, "The Arctium lappa constituents exhibited a great microbial inhibition potential against the tested endodontic pathogens".

More importantly, in the review of the antimicrobial activity against bacteria and yeasts of extracts of 13 Brazilian medicinal plants, researchers found that only 10 plant extracts showed varied levels of antibacterial activity.

Arctium lappa exerted some degree of antibacterial activity compared to other plants, including Mikania glomerata, Sambucus canadensis, Plantago major, and Erythrina species.

Burdock was one of 5 plants belonging to the Asteraceae family that demonstrated Rf values similar to the antibacterial compounds visible on bioautogram.

The finding strongly suggested Burdock and the other 4 plants in the Asteraceae family may be used for the treatment of various infectious diseases.

Taken altogether, herbal Burdock may be considered a functional herb for the prevention and combined with other primary medicine for the treatment of infectious diseases.

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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) In vitro evaluation of the antibacterial activity of Arctium lappa as a phytotherapeutic agent used in intracanal dressings by Gentil M, Pereira JV, Sousa YT, Pietro R, Neto MD, Vansan LP, de Castro França S.(PubMed)
(2) Antimicrobial activity of Arctium lappa constituents against microorganisms commonly found in endodontic infections by Pereira JV, Bergamo DC, Pereira JO, França Sde C, Pietro RC, Silva-Sousa YT.(PubMed)
(3) Screening of some plants used in the Brazilian folk medicine for the treatment of infectious diseases by Holetz FB, Pessini GL, Sanches NR, Cortez DA, Nakamura CV, Filho BP. (PubMed)
(4) Comparative insights into the regulation of inflammation: Levels and predictors of interleukin 6 and interleukin 10 in young adults in the Philippines by Thomas W. McDade,1,2 Paula S. Tallman,1 Linda S. Adair,3 Borja Judith,4 and Christopher W. Kuzawa. (PMC)

#Anthocyanin-Rich #Bilberry #Extract inhibits #SkinDiseases Associated with #ChronicPruritic Symptoms, According to Studies

Kyle J. Norton

Pruritus is a severe itching of the skin, as a symptom of various ailments. It is a frequent complaint heard by dermatologists and primary care physicians.

According to the statistics provided by Dr. Elke Weisshaar and Dr. Uwe Matterne, in children, pruritus is a cardinal symptom of atopic eczema (atopic dermatitis)associated with the prevalent risk between 6.1% and 22.3% in the Western countries.

There are many causes associated with the itching skin including aging that worsened dry skin condition, dry skin, eczema, psoriasis, scabies, burns, scars, insect bites, and hives.and diseases associated with the liver and kidney

Most symptoms of pruritus are due to scratching, including skin redness, bumps, cracks, and scaly skin, depending on the causes of the symptoms.

For some instances, an allergic reaction can induce pruritus involved in touching clothing, pets, chemicals, soaps, and cosmetics, and foods caused by an overreaction of the immune system in the production of cytokines against allergens.

Some researchers suggested that some people may experience an itching feeling with no physical cause. And patients with depression anxiety obsessive-compulsive disorder have been found to have an urge to scratch.

Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.

The plant berry has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.

In finding a potential compound for the treatment of pruritus, researchers at Chiba Univ examined the bilberry anthocyanins' antipruritic effect in a mouse model of allergic contact dermatitis by comparing anthocyanin-rich quality-controlled bilberry extract and anthocyanidin-rich degraded extract.

The study included BALB/c mice with allergic contact dermatitis induced by 4 weeks of repeated application of 2,4,6-trinitro-1-chlorobenzene (TNCB) were administered Bilberon-25 orally for 4 weeks after sensitization with TNCB.

Treatment with non-heated Bilberon-25 significantly attenuated the TNCB-induced increased scratching behavior, whereas treatment with 2 h-heated Bilberon-25 did not.

300 μg/mL nonheated Bilberon-25 showed significant inhibition of degranulation in RBL-2H3 mast cells, whereas 2 h-heated Bilberon-25 had no effect at any concentration.

Further differentiation of the results, researchers found that the efficacy of nonheated Bilberon-25 was attributed to the inhibitory effect of bilberry anthocyanins on pruritus mediated, at least in part, on mast cell degranulation.

More precisely, Dr. Yamaura K, the lead scientist said, "The anthocyanin-rich but not anthocyanidin-rich bilberry extract may be a useful dietary supplement for skin diseases involving pruritic symptoms, such as chronic allergic contact dermatitis, atopic dermatitis, and rhinitis".

Furthermore, in a mouse model induced chronic allergic contact dermatitic researchers once again examined the bilberry extract (Bilberon-25) in the alleviation of pruritus.

The study included BALB/c mice with chronic allergic contact dermatitis induced by 3 weeks of repeated application of 2,4,6-trinitro-1-chlorobenzene (TNCB) were administered Bilberon-25 orally for 3 weeks after sensitization with TNCB.


During the study, treatment with Bilberon-25 significantly attenuated the TNCB-induced increased scratching behavior, but dexamethasone did not.

Both dexamethasone and Bilberon-25 showed a significant amelioration of ear swelling.

Based on these results, researchers wrote in the final report, "Anthocyanins from bilberry might be beneficial for the treatment of chronic pruritus which can occur in patients with inflammatory skin diseases such as atopic dermatitis".

Taken altogether, bilberry processed with a high amount of anthocyanins may be considered a functional food for the treatment of chronic pruritus with no side effects, pending the confirmation of a larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Anthocyanins, but not anthocyanidins, from bilberry (Vaccinium myrtillus L.) alleviate pruritus via inhibition of mast cell degranulation by Yamaura K1, Ishiwatari M, Yamamoto M, Shimada M, Bi Y, Ueno K. (PubMed)
(2) Anthocyanins from bilberry (Vaccinium myrtillus L.) alleviate pruritus in a mouse model of chronic allergic contact dermatitis by Yamaura K1, Shimada M, Ueno K. (PubMed)
(3) Epidemiology of Itch by Elke Weisshaar and Uwe Matterne.(NCBI)

#Bromelain's Phlogenzym Protects the Cardiac Muscle in Blood Circulation Against Damage Caused by ischemia/reperfusion (I/R) Injury

Kyle J. Norton

The cardiac muscle or heart muscle or myocardium is a type of muscle that helps the heart to pump blood to nourish the entire body by performing coordinated contractions.
Damage of the heart muscle can lead to cardiomyopathy, or heart muscle disease, leading to abnormally heart enlarged, thickened, and/or stiffened.

In other words, cardiomyopathy reduced the heart muscle ability to pump blood, causing heart failure and the backup of blood into the lungs or the rest of the body.

Most common types of cardiomyopathy are
* Dilated cardiomyopathy is a condition caused by the enlarged and weakened left ventricle.

* Hypertrophic cardiomyopathy is a result of the thickening of the heart muscle, at the septum between the ventricles, below the aortic valve.

* Ischemic cardiomyopathy is a condition caused by narrow arteries that affect the supply of blood to the heart muscle.

* Restrictive cardiomyopathy is a condition that the walls of the lower chambers of the ventricles are too rigid to expand

Most common symptoms of cardiomyopathy are associated with reduce blood flow due to reduced function of heart muscle including general weakness and fatigue, shortness of breath, particularly during exertion or exercise, lightheadedness, and dizziness, chest pain, heart palpitations, fainting attacks, high blood pressure, edema, or swelling, of your feet, ankles, and legs.

If you have experienced some of the aforementioned symptoms, please check with your doctor to rule out the possibility of cardiomyopathy.

Out of many factors associated with the risk of cardiomyopathy, some researchers suggested that long-term alcoholism may be the major culprit.

Dr. B. Maisch wrote, " Moderate drinking can reduce the incidence and mortality of coronary artery disease, heart failure, diabetes, ischemic and hemorrhagic stroke".


However, "More than this amount can lead to alcoholic cardiomyopathy, which is defined as alcohol toxicity to the heart muscle itself by ethanol and its metabolites".

Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.

With an aim to find a potential ingredient for the improvement of cardiovascular circulation, researchers examined the effect of bromelain on ischemia/reperfusion (IR) injury is characterized by the production of oxygen-free radicals leading to disturbances in vasomotility (microvascular constriction) and microvascular permeability (interstitial edema formation).

The study included a rabbit hindlimb model of I/R (2.5/2 h) were given Phlogenzym, containing rutin, trypsin, and bromelain enterally (60 mg/kg body weight) 30 min prior to ischemia (Ph group).

Before treatment with Phlogenzym, two hours after reperfusion, potassium levels were significantly elevated in IR compared to the Ph group.

Application of Phlogenzym inhibited the enhanced lipid peroxidation, apparent by increased plasma malondialdehyde levels in the Ph group, particularly, in the reduction of blood flow.

Furthermore, Phlogenzym treatment also prevented microvascular constriction and mollified interstitial edema

In other words, Phlogenzym protects the cardiac muscle in blood circulation against damage caused by ischemia/reperfusion (I/R) injury.

Based on the findings, researchers wrote, "Phlogenzym had a protective effect on skeletal muscle during I/R injury expressed by prevention of no-reflow and preservation of muscle tissue".

Taken together, bromelain used alone or combined with conventional medicine may be considered a remedy for the protection of heart muscle, pending the confirmation of the larger sample size and multicenter human study.

Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
Bromelain Osteoarthritis
(1) Properties and Therapeutic Application of Bromelain: A Review by Rajendra Pavan, Sapna Jain, Shraddha, and Ajay Kumar. (PMC)
(2) The result of dosage and individual predisposition. Alcoholic cardiomyopathy by B. Maisch. (PMC)

#Broccoli's Derived Nanoparticle (BDN) and SFN Inhibit Proteins Associated with the Onset of #Colitis in Vivos, According to Studies

Kyle J. Norton

Colitis is a medical condition of inflammation of the large intestine, including the colon, caecum, and rectum.

Types of colitis according to the Catholic University of the Sacred Heart, are including

microscopic colitis, ischemic colitis, segmental colitis associated with diverticula, radiation colitis, diversion colitis, eosinophilic colitis, and Behcet's colitis.

There is no exact cause of colitis. Certain risk factors such as colon infection, inflammatory bowel disease (Crohn's disease, ulcerative colitis), ischemic colitis, allergic reactions, and microscopic colitis have been found to increase the risk of the onset of the condition.

The most common symptoms of colitis are totally depending on the type, including abdominal pain, cramping, and diarrhea, with or without blood in the stool.

The most common risk factors associated with the onset of colitis are Medical conditions such as hypertension, diabetes, hyperlipidemia, atrial fibrillation aging, gender, smoking, depression, psychosocial stress, and family history.

Other risk factors may also contribute to the incidence of colitis, according to the study by Service d'Epidémiologie et de Santé Publique, in a multivariate model are familial history of inflammatory bowel disease (odds ratio (OR) 4.3 (95% confidence interval 2.3-8)), breastfeeding (OR 2.1 (1.3-3.4)), bacille Calmette-Guerin vaccination (OR 3.6 (1.1-11.9)), and history of eczema (OR 2.1 (1-4.5)), disease during pregnancy (OR 8.9 (1.5-52)), and bedroom sharing (OR 7.1 (1.9-27.4)).

Conventionally, besides treating colitis with antibiotics, certain medications also are prescribed to improve the symptoms and quality of life of the patients, including anti-diarrheal medications.

Broccoli is a mustard/cabbage plant, belongings to the family Brassicaceae. The vegetable has large flower heads, usually green in color and the mass of flower heads is surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.

In finding a potential plant that processes anti-colitis activity researchers compared the effects of broccoli-derived nanoparticle (BDN) and SFN on three mouse colitis models.

According to the data collected from the experiment, orally given nanoparticles isolated from broccoli extracts protected mice against colitis by mediating the activation of 5'-adenylic acid-activated protein kinase (AMPK) associated with cellular energy homeostasis.

In the immune analysis, BDN prevented the dendritic cells (DCs) to act as messengers between the innate and the adaptive immune systems in dextran sulfate sodium (DSS)-induced colitis in C57BL/6 (B6) mice by targeting dendritic cells (DCs) activation and inducing DC tolerance.

Compared to BND, DCs pre-pulsed with SFN also prevented DSS-induced colitis in B6 mice,, similar to those of BND.

Taken altogether, broccoli-derived nanoparticle (BDN) or SFN isolated from broccoli may be considered a functional food for the prevention and treatment of colitis, pending the confirmation of the larger sample size and multicenter human study.



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.


Sources
(1) Broccoli-Derived Nanoparticle Inhibits Mouse Colitis by Activating Dendritic Cell AMP-Activated Protein Kinase by Deng Z1, Rong Y1, Teng Y1, Mu J1, Zhuang X1, Tseng M2, Samykutty A1, Zhang L1, Yan J1, Miller D1, Suttles J1, Zhang HG. (PubMed)
(2) Environmental risk factors in paediatric inflammatory bowel diseases: a population based case control study by Baron S1, Turck D, Leplat C, Merle V, Gower-Rousseau C, Marti R, Yzet T, Lerebours E, Dupas JL, Debeugny S, Salomez JL, Cortot A, Colombel JF. (PubMed)

#Herbal #Angelica's Ligustilide (LIG) Inhibits d-gal-Induced CognitiveDysfunction and BrainToxicity, Reserachers Say

Kyle J. Norton

A neuroprotective effect is an event that protects the central nervous system (CNS) by relatively preserving the neuronal structure and/or function.

Neurological diseases are the medical conditions of CNS disorder. Anything that involves structural, biochemical, or electrical abnormalities in the brain, spinal cord, or other nerves, including brain damage is considered as neuro disease.

The most common neurodegenerative diseases in the elderly are dementia. Depending on the brain regions that are damaged or dysfunctional, dementia can be Parkinson's, Alzheimer's, and Huntington's disease.

There are many risk factors involved in the incidence of neurological disorders, including unhealthy lifestyle, infections, genetic preposition, and physical injury.

Genetic mutation inherited from parents such as the NOTCH3 gene is the most common autosomal dominant inherited that causes stroke and vascular dementia.

Oxidative stress is a result of an imbalance of the ratio of levels of free radicals and antioxidants caused either by overexpression of free radicals or depletion of antioxidant enzymes or both.

Free radicals can be produced internally by normal cellular metabolism or from external sources such as the air we breathe, smoking. Free radicals are unstable molecules with unpaired electrons on the outer ring.

In order for them to maintain stability, free radicals must either donate an electron or intercept an electron from other atoms, leading to a chain reaction that can not be stopped until the outer ring electron is paired or inhibited by antioxidants.

Oxidative stress has been found to be a major risk for the onset of neurological disorders in the Western world, particularly in North America.

Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.

The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.

In finding a natural compound for the treatment of neurological diseases, the researchers examined the effects of Ligustilide (LIG) is a principal active ingredient of Radix Angelica Sinensis on neuroprotective activity/

The aging model mice induced by subcutaneous (S.C.) injection of d-gal once daily for 8 weeks followed by LIG (80 mg/kg) were simultaneously administered orally.

Based on the experimental results,
* LIG administration markedly improved behavioral performance of d-gal treated mice.

* LIG reduced the level of neuron stress markers MDA and increased the activity of Na(+)-K(+)-ATPase in the promotion of neurophysiology in the brain of d-gal-induced aging mice.

* Moreover, LIG significantly raised the expression of GAP-43 associated with the development and axonal regeneration and reduced cleaved caspase-3 to promote cell death and GFAP levels in brain injury in the brain of d-gal-treated mice.

Collectively, researchers said, "These results demonstrated that LIG improves d-gal-induced cognitive dysfunction and brain toxicity, which suggests that LIG may be developed as a new medicine for the treatment of age-related conditions".

Taken together, Herbal Angelica may be considered a neuroprotective remedy, pending to larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Ligustilide prevents cognitive impairment and attenuates neurotoxicity in D-galactose induced aging mice brain by Li JJ1, Zhu Q2, Lu YP3, Zhao P3, Feng ZB3, Qian ZM4, Zhu L. (PubMed)

Serum Levels of β-Carotene and α-Carotene in the Body Are Associated Linearly with the Risk of #ERBreastCancer, Researchers Suggest

Kyle J. Norton

The women's breasts are made up of specialized tissue that produces milk (glandular tissue) and fatty tissue. The size of a women's breast is totally determined by the amount of fat.

Cancer is a group of chronic and medical diseases associated with the growth of the irregular cells caused by DNA alternation.

Breast cancer is a medical condition characterized by cell growth irregularly and disorderly in the breast tissue.

Most cases of breast cancer start in the cell on the surface of the inner lining of the breast tissue before spreading into deeper layers of the breast.

In the early stage, most patients with breast cancer may experience lumps on the breast or surrounding the breast.

However, breast skin irritation or dimpling, nipple pain, nipple retraction (turning inward), redness and scaliness that cannot be healed within 3 weeks are also the signs and symptoms of breast cancer.

At the later stage, after colonizing most parts of the breast, the breast cancer cells may travel a distance far the way to infect other healthy cells and tissue.

The causes of breast cancer are unknown, As of today, researchers cannot explain why people with the same health conditions in the same family, some are susceptible to the onset of breast cancer while others do not.

In Canada, according to the statistic, 11% of women will develop breast cancer by the time they reach 90 years of age.

Just about 20% of breast cancers in Canada are diagnosed in women under 50, while almost 30% are diagnosed in women over 70 years of age.

Believe it or not, In 2018, approximately 266,120 new cases of invasive breast cancer were diagnosed in women in the U.S.

The 5 years survival rate of breast cancer diagnosis at the early stage is 100%. Therefore, women at a higher risk of breast cancer should examine their breasts at least once a month for preventive measures.

β-Carotene is a phytochemical in the class of Carotenes, belongings to the group of Carotenoids (tetraterpenoids), found abundantly in dark, leafy greens and red, orange and yellow fruits and vegetable.

In finding a potential phytochemical for the prevention and treatment of cancer, researchers evaluated the associations of plasma carotenoid, retinol, tocopherol, and vitamin C concentrations and risk of breast cancer.


In a nested case-control study within the European Prospective Investigation into Cancer and Nutrition cohort, 1502 female incident breast cancer cases were included, with an oversampling of premenopausal (n = 582) and estrogen receptor-negative (ER-) cases (n = 462). Controls (n = 1502).

According to the tested analysis, α-carotene and β-carotene were inversely associated with risk of ER- breast cancer with the relative odds ration of 0.61 and 0.41 respectively, compared to no statistically in other analytes associated with ER- breast cancer.

Furthermore, β-carotene was a statistically significant difference between ER- and ER+ tumors.

In other words, α-carotene showed no statistical effects on ER+ breast cancer.

However, there was no statistically significant interaction between smoking, alcohol, or BMI and all investigated plasma analytes.

Based on the findings, researchers said, " higher concentrations of plasma β-carotene and α-carotene are associated with lower breast cancer risk of ER- tumors".

Taken together, β-Carotene may be considered a functional food for the prevention and treatment of ER breast cancer, pending to the confirmation of the larger sample size and multicenter human study.

Intake of β-Carotene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the KIarate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Plasma carotenoids, vitamin C, tocopherols, and retinol and the risk of breast cancer in the European Prospective Investigation into Cancer and Nutrition cohort by Bakker MF1, Peeters PH2, Klaasen VM3, Bueno-de-Mesquita HB4, Jansen EH5, Ros MM5, Travier N6, Olsen A7, Tjønneland A7, Overvad K8, Rinaldi S9, Romieu I9, Brennan P9, Boutron-Ruault MC10, Perquier F10, Cadeau C10, Boeing H11, Aleksandrova K11, Kaaks R12, Kühn T12, Trichopoulou A13, Lagiou P14, Trichopoulos D15, Vineis P16, Krogh V17, Panico S18, Masala G19, Tumino R20, Weiderpass E21, Skeie G22, Lund E22, Quirós JR23, Ardanaz E24, Navarro C25, Amiano P26, Sánchez MJ27, Buckland G6, Ericson U28, Sonestedt E28, Johansson M29, Sund M30, Travis RC31, Key TJ31, Khaw KT32, Wareham N33, Riboli E34, van Gils CH. (PubMed)

#Lycopene Inhibits Syndromes Associated with the Onset of Chronic Obstructive Pulmonary Disease (COPD), According to Studies

Kyle J. Norton

The lung-formed part of the circulatory system plays an essential and unique role in taking oxygen to the blood and exhaling carbon dioxide from the blood.

In other words, any diseases involved in breathing problems that reduce the function of the lung are pulmonary diseases.

Lung diseases are a group of medical conditions that cause the reduced function of the lung inhaling oxygen to the blood and exhaling carbon dioxide from the blood.

Pulmonary diseases are a class of diseases associated with the lungs, including asthma, COPD, influenza, pneumonia and tuberculosis, and lung cancer.

Any part of the lung injury can reduce lung function, leading to either obstructive or restrictive lung diseases or mixed lung disease, depending on a person's breathing.

Obstructive lung diseases are condition in which the lungs are unable to expel air properly during exhalation. Diseases associated with obstruction lung diseases care asthma, bronchiectasis, COPD, and emphysema.

Most cases of chronic obstructive pulmonary disease are found in smokers. Dr. Rafael Laniado-Laborín said, "One hundred million deaths were caused by tobacco in the 20th century, and it is estimated that there will be up to one billion deaths attributed to tobacco use in the 21st century.

Chronic obstructive pulmonary disease (COPD) is rapidly becoming a global public health crisis with smoking being recognized as its most important causative factor".


And, "There is mounting evidence that the rate of progression of COPD can be reduced when patients at risk of developing the disease stop smoking, while lifelong smokers have a 50% probability of developing COPD during their lifetime".

Lycopene is a phytochemical found in tomatoes in the class of carotenoids, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,

Tomatoes provide about 80% of the lycopene in the world's diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.

In finding a potential compound for the treatment of lung disease, researchers examined lycopene effects on COPD on a nonrodent model.

The study included ferrets (4 groups, n = 12-16/group) exposed to a combination of tobacco carcinogen (NNK) and CS with or without consuming lycopene at low and high doses (equivalent to ∼30 and ∼90 mg lycopene/day in human, respectively) for 22 weeks.

According to tested analysis, lycopene at a high dose significantly inhibited NNK/CS-induced chronic bronchitis, emphysema, and preneoplastic lesions in the induction of chronic obstructive pulmonary disease by decreasing lung growth abnormally.

Furthermore, lycopene also significantly inhibited NNK/CS-induced accumulation of total cholesterol and increased mRNA expression of critical genes related to the reverse cholesterol transport (RCT) ) in the lungs.

Based on the findings, researchers said, "The present study has provided the first evidence linking a protective role of dietary lycopene against COPD and preneoplastic lesions to RCT-mediated cholesterol accumulation in lungs".

Taken together, lycopene found in tomatoes may be considered an anti-COPD remedy for the prevention and treatment of UC, pending the confirmation of the larger sample size and multicenter human study.

Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Lycopene Inhibits Smoke-Induced Chronic Obstructive Pulmonary Disease and Lung Carcinogenesis by Modulating Reverse Cholesterol Transport in Ferrets by Mustra Rakic J1,2, Liu C1, Veeramachaneni S1, Wu D2,3, Paul L2,4, Chen CO2, Ausman LM1,2, Wang XD. (PubMed)
(2) Smoking and Chronic Obstructive Pulmonary Disease (COPD). Parallel Epidemics of the 21st Century by Rafael Laniado-Laborín. (PMC)