Kyle J. Norton
Scientists may have found a natural and potent herbal plant used for the delay of skin aging, according to the studies.
Skin aging is a natural and biological process the human that can be stopped.
Long-term free radical damage to the skin through oxidative stress is the major cause of skin aging.
Exposure to the sun (photoaging) and pollution, and loss of subcutaneous support (fatty tissue between your skin and muscle) are some of the risk factors associated with skin aging.
Some researchers suggested that skin expression may be considered a refect of the general health of an individual. Unhealthy skin due to skin nutritional deficiency has been a target of the dermatology and cosmetic industries.
Dr.Silke K. Schagen in the study that links nutrition and skin aging, said, "Vitamins, carotenoids, tocopherols, flavonoids and a variety of plant extracts have been reported to possess potent antioxidant properties and have been widely used in the skin care industry either as topically applied agents or oral supplements in an attempt to prolong youthful skin appearance".
The results strongly suggested that by providing enough nutrition to the skin's needs, extrinsic causes of skin aging can be delayed
In skin wrinkle, according to the results of the studies by Monash University, Melbourne, a high intake of certain food groups are associated with the speeding up of wrinkle, including meat, dairy, and butter. A high intake of vegetables, legumes, and olive oil appeared to be protective against cutaneous actinic damage.
Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan. It has become very popular for commercial cultivation due to its health benefits.
The herbal plant has been used in herbal medicine in treating many kinds of diseases, including wounds, burn healing, minor skin infections, sebaceous cysts, diabetes, elevated cholesterol, etc. It is also one of many popular herbs studied in scientific ways with some conflicting results.
The ten main areas of chemical constituents of Aloe vera include amino acids, anthraquinones, enzymes, minerals, vitamins, lignins, monosaccharides, polysaccharides, salicylic acid, saponins, and sterols.
They all work together in a synergistic way to create healing and health-giving benefits, according to Gertrude Baldwin in the article THE BENEFITS OF THE USE OF ALOE VERA IN HERBAL PREPARATIONS.
With an aim to find a natural ingredient or whole food for the delay of skin aging researchers at the Seoul National University Boramae Hospital examined the effect of aloe gel on the clinical signs and biochemical changes of aging skin.
The experiment included 30 healthy female subjects over the age of 45 given 2 different doses (low-dose: 1,200 mg/d, high-dose: 3,600 mg/d) of aloe vera gel supplementation for 90 days with their baseline status as a control.
Aloe gel intake inhibits skin facial wrinkles significantly (p<0.05) in both groups, and facial elasticity improved in the lower-dose group.
The injection of the gel also increased the skin photoprotection and the type I procollagen mRNA levels in controlling the rate of procollagen synthesis.
The results were accompanied by the matrix (MMP-1) mRNA levels associated with the breaking down of the interstitial collagens, types I, II, and III, particularly in the higher-dose group.
Type I procollagen was substantially increased throughout the dermis in Aloe treatment of the group.
Dr. Cho S, the lead scientist said, "Aloe gel significantly improves wrinkles and elasticity in photoaged human skin, with an increase in collagen production in the photoprotected skin and a decrease in the collagen-degrading MMP-1 gene expression".
The Kyung Hee University Global Campus in the investigation of the effects of Aloe vera on ultraviolet (UV) irradiation induces photo-damage of the skin, which in turn causes depletion of the dermal extracellular matrix and chronic alterations in skin structure.
By the comparison of the baby Aloe shoot extract (BAE, immature aloe extract), which is from the one-month-old shoots of Aloe vera, and adult aloe shoot extract (AE), which is from the four-month-old shoots of Aloe vera, protective effect on UVB-induced skin photoaging in normal human dermal fibroblasts (NHDFs). researchers found that NHDF cells treated UVB-irradiation suppressed the matrixes associated with the breaking down the interstitial collagens, types I, II, and III, and the levels of inflammatory cytokines similar to that of the above study, compared to the AE-treated cells.
BAE treatment elevated type I procollagen which was reduced in photodamaged skin. mediated by the increasing levels of TGF-β1 levels which is a multifunctional cytokine.
The findings clearly suggested that herbal Aloe vera may be considered an anti-aging functional remedy with no side effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Dietary Aloe Vera Supplementation Improves Facial Wrinkles and Elasticity and It Increases the Type I Procollagen Gene Expression in Human Skin in vivo. by Cho S, Lee S, Lee MJ, Lee DH, Won CH, Kim SM, Chung JH. (PubMed)
(2) A Comparative Study of Baby Immature and Adult Shoots of Aloe Veraon UVB-Induced Skin Photoaging in vitro. by Hwang E, Kim SH, Lee S, Lee CH, Do SG, Kim J, Kim SY. (PubMed)
(3) Innovations in natural ingredients and their use in skin care.
(4) Discovering the link between nutrition and skin aging by Silke K. Schagen, † Vasiliki A. Zampeli, † Evgenia Makrantonaki, and Christos C. Zouboulis. (PMC)
(5) Skin wrinkling: can food make a difference? by Purba MB1, Kouris-Blazos A, Wattanapenpaiboon N, Lukito W, Rothenberg EM, Steen BC, Wahlqvist ML. (PubMed)
(6) Prevalence of Helicobacter pylori Infection in Patients with Peptic Ulcer Diseases and Non-Ulcer Dyspepsia by Hyo Rang Lee, M.D., Ki Soo Han, M.D., Byung Chul Yoo, M.D., and Sill Moo Park, M.D. (PMC)
Wednesday, 21 June 2023
#RegularWalking Reduces the Risk of Hip/Knee #Osteoarthritis in Older Adults, Researchers Suggest
Kyle J. Norton
Regular physical activity has long been found to associate with the prevention of cancer, cardiovascular disease, and other chronic diseases, but the regular walking contribution to health benefits of reduced risk of osteoarthritis in the younger and older elderly have been controversial.
Osteoarthritis (OA), a form of arthritis, is a condition or as a result of aging causes of wear and tear on a joint, affecting over 25 million people in the United States alone. University of Porto Medical School indicated that one must understand the differences in prevalence and incidence estimates of osteoarthritis (OA), according to case definition, in the knee, hip, and hand joints.
The characteristics of osteoarthritis are aching pain, stiffness, or difficulty in moving the joint or joints. The pain usually gets worse in a change of weather, at night, and in advanced diseases, the pain can occur even at rest(8). Today management of osteoarthritis (OA) focuses on pain relief and improved physical function through pharmacological, nonpharmacological, and surgical treatments(10).
Moderate physical activity and walking programs had a positive effect on the quality of life of elderly individuals with knee OA, a new study suggested(5), through reduction of pain and improvement of physical function(6).
According to Dr. Evcik D and Dr. Sonel B., simple home-based exercise therapy and a regular walking program are effective in treating the symptoms of OA(7).
In older others with the preexisted condition of hip/knee OA, PA may reduce the risk of hip/knee OA, especially among women with no association between hip/knee OA and low joint stress(1).
In support of the effectiveness of physical exercise without increasing the risk of hip/knee OA and joint stress, Dr. Hootman JM and colleagues at the National Center for Chronic Disease Prevention and Health Promotion, said, "The joint stress PA score was not associated with an increased risk of hip/knee OA. Also, among walkers and runners, there was no association between the frequency, pace, or weekly training mileage and hip/knee OA"(2).
In fact, of the 4316 people originally interviewed, 216 eligible cases (66 men, 150 women) were identified (mean age 57.1) insisted, there was little evidence to suggest that increased levels of regular physical activity throughout life lead to an increased risk of knee OA later in life(3) with exception to those of overweight(4).
Indeed, regular walking at one own pace is associated with a reduced risk of hip and knee osteoarthritis (OA)(8). Exercise and sports may probably be also a preventive tool against osteoarthritis, due to its positive effect on weight, muscle strength, and possibly synovial inflammation(9).
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) The association between joint stress from physical activity and self-reported osteoarthritis: an analysis of the Cooper Clinic data by Rogers LQ1, Macera CA, Hootman JM, Ainsworth BE, Blairi SN.(PubMed)
(2) Influence of physical activity-related joint stress on the risk of self-reported hip/knee osteoarthritis: a new method to quantify physical activity by Hootman JM1, Macera CA, Helmick CG, Blair SN. (PubMed)
(3) A case-control study to investigate the relation between low and moderate levels of physical activity and osteoarthritis of the knee using data collected as part of the Allied Dunbar National Fitness Survey by Sutton AJ1, Muir KR, Mockett S, Fentem P.(PubMed)
(4) A case-control study to investigate the relation between low and moderate levels of physical activity and osteoarthritis of the knee using data collected as part of the Allied Dunbar National Fitness Survey by Sutton AJ1, Muir KR, Mockett S, Fentem P.(PubMed)
(5) Impact of an exercise and walking protocol on quality of life for elderly people with OA of the knee by Dias RC1, Dias JM, Ramos LR.(PubMed)
(6) Exercise for osteoarthritis of the knee by Fransen M1, McConnell S, Harmer AR, Van der Esch M, Simic M, Bennell KL.(PubMed)
(7) Effectiveness of a home-based exercise therapy and walking program on osteoarthritis of the knee by Evcik D1, Sonel B.(PubMed)
(8) Exercise and osteoarthritis by David J Hunter1,2 and Felix Eckstein3,4(PMC)
(9) [Exercise--sports and osteoarthritis].[Article in French] by Ziltener JL1, Leal S, Borloz S.(PubMed)
(10) Most Common diseases of elder: The Clinical Trials and Studies of Osteoarthritis Back by Respectable Institutions by Kyle J. Norton
Regular physical activity has long been found to associate with the prevention of cancer, cardiovascular disease, and other chronic diseases, but the regular walking contribution to health benefits of reduced risk of osteoarthritis in the younger and older elderly have been controversial.
Osteoarthritis (OA), a form of arthritis, is a condition or as a result of aging causes of wear and tear on a joint, affecting over 25 million people in the United States alone. University of Porto Medical School indicated that one must understand the differences in prevalence and incidence estimates of osteoarthritis (OA), according to case definition, in the knee, hip, and hand joints.
The characteristics of osteoarthritis are aching pain, stiffness, or difficulty in moving the joint or joints. The pain usually gets worse in a change of weather, at night, and in advanced diseases, the pain can occur even at rest(8). Today management of osteoarthritis (OA) focuses on pain relief and improved physical function through pharmacological, nonpharmacological, and surgical treatments(10).
Moderate physical activity and walking programs had a positive effect on the quality of life of elderly individuals with knee OA, a new study suggested(5), through reduction of pain and improvement of physical function(6).
According to Dr. Evcik D and Dr. Sonel B., simple home-based exercise therapy and a regular walking program are effective in treating the symptoms of OA(7).
In older others with the preexisted condition of hip/knee OA, PA may reduce the risk of hip/knee OA, especially among women with no association between hip/knee OA and low joint stress(1).
In support of the effectiveness of physical exercise without increasing the risk of hip/knee OA and joint stress, Dr. Hootman JM and colleagues at the National Center for Chronic Disease Prevention and Health Promotion, said, "The joint stress PA score was not associated with an increased risk of hip/knee OA. Also, among walkers and runners, there was no association between the frequency, pace, or weekly training mileage and hip/knee OA"(2).
In fact, of the 4316 people originally interviewed, 216 eligible cases (66 men, 150 women) were identified (mean age 57.1) insisted, there was little evidence to suggest that increased levels of regular physical activity throughout life lead to an increased risk of knee OA later in life(3) with exception to those of overweight(4).
Indeed, regular walking at one own pace is associated with a reduced risk of hip and knee osteoarthritis (OA)(8). Exercise and sports may probably be also a preventive tool against osteoarthritis, due to its positive effect on weight, muscle strength, and possibly synovial inflammation(9).
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) The association between joint stress from physical activity and self-reported osteoarthritis: an analysis of the Cooper Clinic data by Rogers LQ1, Macera CA, Hootman JM, Ainsworth BE, Blairi SN.(PubMed)
(2) Influence of physical activity-related joint stress on the risk of self-reported hip/knee osteoarthritis: a new method to quantify physical activity by Hootman JM1, Macera CA, Helmick CG, Blair SN. (PubMed)
(3) A case-control study to investigate the relation between low and moderate levels of physical activity and osteoarthritis of the knee using data collected as part of the Allied Dunbar National Fitness Survey by Sutton AJ1, Muir KR, Mockett S, Fentem P.(PubMed)
(4) A case-control study to investigate the relation between low and moderate levels of physical activity and osteoarthritis of the knee using data collected as part of the Allied Dunbar National Fitness Survey by Sutton AJ1, Muir KR, Mockett S, Fentem P.(PubMed)
(5) Impact of an exercise and walking protocol on quality of life for elderly people with OA of the knee by Dias RC1, Dias JM, Ramos LR.(PubMed)
(6) Exercise for osteoarthritis of the knee by Fransen M1, McConnell S, Harmer AR, Van der Esch M, Simic M, Bennell KL.(PubMed)
(7) Effectiveness of a home-based exercise therapy and walking program on osteoarthritis of the knee by Evcik D1, Sonel B.(PubMed)
(8) Exercise and osteoarthritis by David J Hunter1,2 and Felix Eckstein3,4(PMC)
(9) [Exercise--sports and osteoarthritis].[Article in French] by Ziltener JL1, Leal S, Borloz S.(PubMed)
(10) Most Common diseases of elder: The Clinical Trials and Studies of Osteoarthritis Back by Respectable Institutions by Kyle J. Norton
#Indoles, #specially #I3C and #DIM Exert a Hepatic Protection through Pleiotropic Mechanism, According to Studies
Kyle J. Norton
Scientists may have found a bioactive ingredient that processes liver protective activity with no side effects, according to studies.
Hepatic protection is an action in which substances including medicine and herbal remedy were used to protect the liver against damage.
The liver is the largest internal organ with a function that filters the blood from the intestinal tract before passing them to the heart and other parts of the body.
Additionally, the liver also produces bile to aid digestion and cholesterol to build strong cell membranes and production of vitamin D and steroid hormones.
Liver disease is a broad term including any problems that cause the reduced function of the liver.
There are many risk factors that liver problems. Most cases of liver disease are diagnosed in the advanced stage, it takes years to develop.
In other words, symptoms of liver disease can be felt only after more than 75% liver is damaged.
The most common risk factors are genetic preposition, viruses, and long-term excessive alcohol drinking.
Non-alcoholic fatty disease (NAFLD), a leading cause of cirrhosis, is one of the most common liver diseases found in the Western world, affecting up to 25% of people in the United States.
3,3'-Diindolylmethane or DIM are phytochemicals derived from the digestion of indole-3-carbinol, belonging to the group of Indoles, found abundantly in broccoli, Brussels sprouts, cabbage, kale, etc.
In the urgency of finding a natural compound with liver protective activity, researchers examined the pharmacokinetics of I3C and its derivatives, including 3,3'-Diindolylmethane or DIM multiple protective roles in the processes of chronic liver diseases.
Administration of I3C and its derivatives relieved liver oxidative stress by regulating transcriptional factors and their respective signaling pathways associated with the synthesis of DNA to influence the activation, proliferation, and apoptosis of target cells.
Furthermore, indoles not only modulated the enzymes that are relevant to hepatitis viral replication, lipogenesis, and the metabolism associated with liver function but also protected the liver against hepatotoxicity (ethanol and some hepatotoxic substances).
In other words, the indoles exerted hepatoprotection by inhibiting pro-inflammatory cytokines and chemokines against microbial-induced liver injuries.
Based on the findings, Dr. Wang SQ, the lead scientist said, "Indoles, especially I3C and DIM as phytochemicals, exert anti-fibrosis, anti-tumor, anti-oxidant, immunomodulatory, detoxification and anti-inflammation effects on hepatic protection through pleiotropic mechanism".
And, " I3C and DIM as phytochemicals, exert anti-fibrosis, anti-tumor, anti-oxidant, immunomodulatory, detoxification and anti-inflammation effects on hepatic protection through pleiotropic mechanism".
Taken altogether, 3,3'-Diindolylmethane derived from the digestion of indole-3-carbinol may be considered a supplement for the prevention and treatment of liver diseases, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Indole-3-Carbinol (I3C) and its Major Derivatives: Their Pharmacokinetics and Important Roles in Hepatic Protection by Wang SQ, Cheng LS, Liu Y, Wang JY, Jiang W. (PubMed)
(2) Induction of hepatic CYP1A by indole-3-carbinol in protection against aflatoxin B1 hepatocarcinogenesis in rainbow trout by Takahashi N1, Stresser DM, Williams DE, Bailey GS. (PubMed)
Scientists may have found a bioactive ingredient that processes liver protective activity with no side effects, according to studies.
Hepatic protection is an action in which substances including medicine and herbal remedy were used to protect the liver against damage.
The liver is the largest internal organ with a function that filters the blood from the intestinal tract before passing them to the heart and other parts of the body.
Additionally, the liver also produces bile to aid digestion and cholesterol to build strong cell membranes and production of vitamin D and steroid hormones.
Liver disease is a broad term including any problems that cause the reduced function of the liver.
There are many risk factors that liver problems. Most cases of liver disease are diagnosed in the advanced stage, it takes years to develop.
In other words, symptoms of liver disease can be felt only after more than 75% liver is damaged.
The most common risk factors are genetic preposition, viruses, and long-term excessive alcohol drinking.
Non-alcoholic fatty disease (NAFLD), a leading cause of cirrhosis, is one of the most common liver diseases found in the Western world, affecting up to 25% of people in the United States.
3,3'-Diindolylmethane or DIM are phytochemicals derived from the digestion of indole-3-carbinol, belonging to the group of Indoles, found abundantly in broccoli, Brussels sprouts, cabbage, kale, etc.
In the urgency of finding a natural compound with liver protective activity, researchers examined the pharmacokinetics of I3C and its derivatives, including 3,3'-Diindolylmethane or DIM multiple protective roles in the processes of chronic liver diseases.
Administration of I3C and its derivatives relieved liver oxidative stress by regulating transcriptional factors and their respective signaling pathways associated with the synthesis of DNA to influence the activation, proliferation, and apoptosis of target cells.
Furthermore, indoles not only modulated the enzymes that are relevant to hepatitis viral replication, lipogenesis, and the metabolism associated with liver function but also protected the liver against hepatotoxicity (ethanol and some hepatotoxic substances).
In other words, the indoles exerted hepatoprotection by inhibiting pro-inflammatory cytokines and chemokines against microbial-induced liver injuries.
Based on the findings, Dr. Wang SQ, the lead scientist said, "Indoles, especially I3C and DIM as phytochemicals, exert anti-fibrosis, anti-tumor, anti-oxidant, immunomodulatory, detoxification and anti-inflammation effects on hepatic protection through pleiotropic mechanism".
And, " I3C and DIM as phytochemicals, exert anti-fibrosis, anti-tumor, anti-oxidant, immunomodulatory, detoxification and anti-inflammation effects on hepatic protection through pleiotropic mechanism".
Taken altogether, 3,3'-Diindolylmethane derived from the digestion of indole-3-carbinol may be considered a supplement for the prevention and treatment of liver diseases, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Indole-3-Carbinol (I3C) and its Major Derivatives: Their Pharmacokinetics and Important Roles in Hepatic Protection by Wang SQ, Cheng LS, Liu Y, Wang JY, Jiang W. (PubMed)
(2) Induction of hepatic CYP1A by indole-3-carbinol in protection against aflatoxin B1 hepatocarcinogenesis in rainbow trout by Takahashi N1, Stresser DM, Williams DE, Bailey GS. (PubMed)
#Healthyfood Tomatoes Inhibit the Risk of Colitis Through Its #Antiinflammatory Activities In Vivos, Researchers Say
Kyle J. Norton
Colitis is chronic a condition associated with the inflammation of the large intestine, including the colon, caecum, and rectum.
Colitis can be classified into the microscopic colitis, ischemic colitis, segmental colitis associated with diverticula, radiation colitis, diversion colitis, eosinophilic colitis and Behcet's colitis(a), according to the Catholic University of the Sacred Heart.
Most common symptoms of colitis are totally depending on the types. However, the general symptoms include
* Adnominal pain and diarrhea
There is a report of a 25-year-old Iranian gentleman who was admitted to the hospital with severe bloody diarrhea and abdominal pain as a result of herbal-induced weight loss adverse effects. On flexible sigmoidoscopy, a continuous length of congested mucosa with multiple small ulcers was seen extending up to the mid-transverse colon, in keeping with ulcerative colitis, according to the study by
Homerton University Hospital NHS Foundation Trust(1)
2. Bleeding per rectum
Acute ischaemic colitis (AIC) is being increasingly recognized as an uncommon cause of abdominal pain associated with fresh bleeding per rectum and diarrhea, according to the study by University Central Hospital(2).
3. Distention with bloody diarrhea
The typical clinical presentation is acute sudden abdominal pain and distention with bloody diarrhea(3).
4. Abdominal bloating and flatulence
In the study to estimate the prevalence of microscopic colitis and SIBO in patients with IBS, to evaluate the symptoms and the efficacy of treatment found that out of the 132 patients initially diagnosed with IBS 3% (n=4) had microscopic colitis and 43.9% (n=58) had SIBO. Diarrhea was the main symptom in patients with microscopic colitis and SIBO (p=0.041), while abdominal pain, abdominal bloating, and flatulence were prominent in IBS patients (p=0.042; p=0.039; p=0.048)(4).
5. Changes in bowel habits
Abdominal pain, bloating, early satiety, and changes in bowel habits are common presenting symptoms in individuals with functional GI disorders(5).
6. Fever and severe dehydration
There is a report of a 19-year-old man with a 1-year history of ulcerative colitis presented with fever, bloody diarrhea, and severe dehydration. He was on po.48 mg methylprednisolone and 3 g mesalazine daily and has recently finished taking clarithromycin for Campylobacter jejuni infection(6).
7. Urgency
The study to examine the differing perspectives and perceptual gaps relating to ulcerative colitis (UC) symptoms and their management between patients and healthcare professionals (HCPs), indicated that fifty-five percent of patients stated that UC symptoms over the past year had affected their quality of life, while physicians and nurses estimated that 35% to 37% of patients would have a reduced quality of life over the same period. Patients ranked urgency and pain as the most bothersome symptoms(7)
8. Other symptoms
There is a report of a case of a 51-year-old Caucasian male who was evaluated for abdominal pain, elevated liver enzymes, leukopenia, thrombocytopenia, severe peripheral arthralgias, and chronic watery diarrhea as a result of granulomatous enterocolitis. due to Sarcoidosis(8). Another study conducted by Anhui University of Traditional Chinese Medicine, with rats in the model group, showed lethargy, poor appetite, loss of energy, diarrhea, and bloody stool(9).
If you have experienced some of the aforementioned symptoms persistently with no signs of stopping, please make sure you check with your doctor to rule out the possibility of colitis.
Tomato is a red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.
In finding healthy foods for the treatment of colitis, researchers examined the impact of tomato lycopene extract (TLE) on intestinal inflammation.
The study included mice lipopolysaccharide (LPS)-induced innate signaling and experimental colitis fed a diet containing 0.5 and 2% TLE or isoflavone free control (AIN-76).
According to the tested assays, TLE blocked LPS-induced IkappaBalpha degradation and RelA translocation associated with the onset of colitis by blocking the inhibition of the protein involved in cytokine production.
Furthermore, MIP-2, a small cytokine mRNA accumulation in IEC-18 cells, and pro-inflammatory cytokine Interleukin 12 (IL-12) induced by LPS were inhibited by the injection of TLE.
Moreover, the application of TLE also increased the expression of anti-inflammatory cytokines IL-6, TNF-alpha, a regulator of inflammation, and MCP-1 mRNA associated with macrophage recruitment in the colon of TLE-fed subjects.
The results strongly suggested that tomato extract inhibited colitis in mice through its modulatory of immune and inflammatory activity.
Taken altogether, tomatoes may be considered a dietary supplement for the prevention and treatment of colitis, pending to large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Tomato lycopene extract prevents lipopolysaccharide-induced NF-kappaB signaling but worsens dextran sulfate sodium-induced colitis in NF-kappaBEGFP mice by Joo YE1, Karrasch T, Mühlbauer M, Allard B, Narula A, Herfarth HH, Jobin C. (PubMed)
(2) Colitis - Types and Symptoms by Kyle J. Norton
Colitis is chronic a condition associated with the inflammation of the large intestine, including the colon, caecum, and rectum.
Colitis can be classified into the microscopic colitis, ischemic colitis, segmental colitis associated with diverticula, radiation colitis, diversion colitis, eosinophilic colitis and Behcet's colitis(a), according to the Catholic University of the Sacred Heart.
Most common symptoms of colitis are totally depending on the types. However, the general symptoms include
* Adnominal pain and diarrhea
There is a report of a 25-year-old Iranian gentleman who was admitted to the hospital with severe bloody diarrhea and abdominal pain as a result of herbal-induced weight loss adverse effects. On flexible sigmoidoscopy, a continuous length of congested mucosa with multiple small ulcers was seen extending up to the mid-transverse colon, in keeping with ulcerative colitis, according to the study by
Homerton University Hospital NHS Foundation Trust(1)
2. Bleeding per rectum
Acute ischaemic colitis (AIC) is being increasingly recognized as an uncommon cause of abdominal pain associated with fresh bleeding per rectum and diarrhea, according to the study by University Central Hospital(2).
3. Distention with bloody diarrhea
The typical clinical presentation is acute sudden abdominal pain and distention with bloody diarrhea(3).
4. Abdominal bloating and flatulence
In the study to estimate the prevalence of microscopic colitis and SIBO in patients with IBS, to evaluate the symptoms and the efficacy of treatment found that out of the 132 patients initially diagnosed with IBS 3% (n=4) had microscopic colitis and 43.9% (n=58) had SIBO. Diarrhea was the main symptom in patients with microscopic colitis and SIBO (p=0.041), while abdominal pain, abdominal bloating, and flatulence were prominent in IBS patients (p=0.042; p=0.039; p=0.048)(4).
5. Changes in bowel habits
Abdominal pain, bloating, early satiety, and changes in bowel habits are common presenting symptoms in individuals with functional GI disorders(5).
6. Fever and severe dehydration
There is a report of a 19-year-old man with a 1-year history of ulcerative colitis presented with fever, bloody diarrhea, and severe dehydration. He was on po.48 mg methylprednisolone and 3 g mesalazine daily and has recently finished taking clarithromycin for Campylobacter jejuni infection(6).
7. Urgency
The study to examine the differing perspectives and perceptual gaps relating to ulcerative colitis (UC) symptoms and their management between patients and healthcare professionals (HCPs), indicated that fifty-five percent of patients stated that UC symptoms over the past year had affected their quality of life, while physicians and nurses estimated that 35% to 37% of patients would have a reduced quality of life over the same period. Patients ranked urgency and pain as the most bothersome symptoms(7)
8. Other symptoms
There is a report of a case of a 51-year-old Caucasian male who was evaluated for abdominal pain, elevated liver enzymes, leukopenia, thrombocytopenia, severe peripheral arthralgias, and chronic watery diarrhea as a result of granulomatous enterocolitis. due to Sarcoidosis(8). Another study conducted by Anhui University of Traditional Chinese Medicine, with rats in the model group, showed lethargy, poor appetite, loss of energy, diarrhea, and bloody stool(9).
If you have experienced some of the aforementioned symptoms persistently with no signs of stopping, please make sure you check with your doctor to rule out the possibility of colitis.
Tomato is a red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.
In finding healthy foods for the treatment of colitis, researchers examined the impact of tomato lycopene extract (TLE) on intestinal inflammation.
The study included mice lipopolysaccharide (LPS)-induced innate signaling and experimental colitis fed a diet containing 0.5 and 2% TLE or isoflavone free control (AIN-76).
According to the tested assays, TLE blocked LPS-induced IkappaBalpha degradation and RelA translocation associated with the onset of colitis by blocking the inhibition of the protein involved in cytokine production.
Furthermore, MIP-2, a small cytokine mRNA accumulation in IEC-18 cells, and pro-inflammatory cytokine Interleukin 12 (IL-12) induced by LPS were inhibited by the injection of TLE.
Moreover, the application of TLE also increased the expression of anti-inflammatory cytokines IL-6, TNF-alpha, a regulator of inflammation, and MCP-1 mRNA associated with macrophage recruitment in the colon of TLE-fed subjects.
The results strongly suggested that tomato extract inhibited colitis in mice through its modulatory of immune and inflammatory activity.
Taken altogether, tomatoes may be considered a dietary supplement for the prevention and treatment of colitis, pending to large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Tomato lycopene extract prevents lipopolysaccharide-induced NF-kappaB signaling but worsens dextran sulfate sodium-induced colitis in NF-kappaBEGFP mice by Joo YE1, Karrasch T, Mühlbauer M, Allard B, Narula A, Herfarth HH, Jobin C. (PubMed)
(2) Colitis - Types and Symptoms by Kyle J. Norton
Yoga Protects the Gene Expression Against the Risk of Related Diseases, Researchers Show
Kyle J. Norton
Yoga intervention may have a potential effect on regulated gene expression in some related diseases, researchers at the University of Oslo suggested.
Mutated gene expression included many factors, most common factors are
1. Gene mutation inherited from gene defect parents
2. Gene expression may be altered in the process of regulatory sequences and the transcription factors, cofactors, chromatin regulators, and noncoding RNAs
3. Gene mutation is a natural process to protect the existence of human beings. Unfortunately, the process in some cases may produce certain subgroups who are vulnerable and susceptible to some diseases.
Biologically, unnatural causes of gene expression due to prolonged exposure to certain harmful agents such as environmental toxins, and the long-term use of single or multi ingredients medication,... may also induce genetic change in negative ways.
Diseases caused by mutated gene expression, include cancer, autoimmunity, neurological disorders, diabetes...
Yoga, the ancient technique for harmonizing external and internal body well beings, through breath control, meditation, bodily movement, and gesture..... has been best known to people in the Western world and some parts of Asia due to health benefits reported by various respectable institutes research and supported by health advocates.
In the study to investigate whether the effects on the mind-body system increased wellness and supported the healing process from diseases, researchers found that yoga intervention not only improved psychological and physiological functioning but also may have regulated effects in gene expression profiling in circulating immune cells, particularly at the molecular level.
Indeed, yoga can improve immunity through a sequence of the post in strengthening the body and relaxing the mind. Some believed that by strengthening the body and relaxing the mind, yoga acted as a regulator of gene expression in the innate and adaptive cells of the immune system, through noncoding RNAs, thus reducing the risk of inflammatory and autoimmune diseases.
In further exploration of the yoga effect in gene expression at the molecular level, researchers at the joint study led by Coventry University postulated that mind-body interventions (MBIs) showed a significantly reverse expression of genes involved in inflammatory reactions induced by stress.
Yoga, a mind-body practice of physical poses, controlled breathing, and meditation or relaxation has been best known to reduce the implication of stress in increased production of inflammatory cytokines in gene expression, including interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF alpha), thus reducing the risk of inflammatory diseases.
And after examining the changes in gene expression that occur after MBIs and exploring how these molecular changes are related to health, through searching the database of published literature from PubMed throughout September 2016, research indicated that overall studies selected indicated an association of gene changes in yoga intervention was a result downregulation of nuclear factor kappa B pathway.
Furthermore, MBI practices may lead to a reduced risk of inflammation-related diseases, through the reduced effects of chronic stress on gene expression.
Most interestingly, in the assessed possible rapid changes in global gene expression profiles in the peripheral blood mononuclear cells (PBMCs) in healthy people who practiced either a comprehensive yoga program or a control regimen, researchers found that the SK&P program has a more rapid and significant greater effect on gene expression in PBMCs compared with the control regimen.
Peripheral blood mononuclear cells (PBMC) include lymphocytes (T cells, B cells, NK cells), monocytes, and granulocytes which play an important role in improving immune system cellular function in fighting against infection and inflammation, enhanced tissue regeneration, restored function due to injuring, .....
Truly, the impact of yoga in the protection of gene expression of the immune system may involve a complexity of simple gene regulatory networks (GRNs), including the gene expression in PBMCs and inflammatory cytokines
Taken together, Yoga intervention and related practices may have a profound effect on gene expression alterations through a complex network of simple gene regulation in the immune system.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.
Sources
(1) Regulation of gene expression by yoga, meditation and related practices: a review of recent studies by Saatcioglu F1(PubMed)
(2) Rapid gene expression changes in peripheral blood lymphocytes upon practice of a comprehensive yoga program by Qu S1, Olafsrud SM, Meza-Zepeda LA, Saatcioglu F.(PubMed)
(3) What Is the Molecular Signature of Mind-Body Interventions? A Systematic Review of Gene Expression Changes Induced by Meditation and Related Practices by Buric I1,2, Farias M1, Jong J1, Mee C3, Brazil IA1,2,4,5.(PubMed)
Yoga intervention may have a potential effect on regulated gene expression in some related diseases, researchers at the University of Oslo suggested.
Mutated gene expression included many factors, most common factors are
1. Gene mutation inherited from gene defect parents
2. Gene expression may be altered in the process of regulatory sequences and the transcription factors, cofactors, chromatin regulators, and noncoding RNAs
3. Gene mutation is a natural process to protect the existence of human beings. Unfortunately, the process in some cases may produce certain subgroups who are vulnerable and susceptible to some diseases.
Biologically, unnatural causes of gene expression due to prolonged exposure to certain harmful agents such as environmental toxins, and the long-term use of single or multi ingredients medication,... may also induce genetic change in negative ways.
Diseases caused by mutated gene expression, include cancer, autoimmunity, neurological disorders, diabetes...
Yoga, the ancient technique for harmonizing external and internal body well beings, through breath control, meditation, bodily movement, and gesture..... has been best known to people in the Western world and some parts of Asia due to health benefits reported by various respectable institutes research and supported by health advocates.
In the study to investigate whether the effects on the mind-body system increased wellness and supported the healing process from diseases, researchers found that yoga intervention not only improved psychological and physiological functioning but also may have regulated effects in gene expression profiling in circulating immune cells, particularly at the molecular level.
Indeed, yoga can improve immunity through a sequence of the post in strengthening the body and relaxing the mind. Some believed that by strengthening the body and relaxing the mind, yoga acted as a regulator of gene expression in the innate and adaptive cells of the immune system, through noncoding RNAs, thus reducing the risk of inflammatory and autoimmune diseases.
In further exploration of the yoga effect in gene expression at the molecular level, researchers at the joint study led by Coventry University postulated that mind-body interventions (MBIs) showed a significantly reverse expression of genes involved in inflammatory reactions induced by stress.
Yoga, a mind-body practice of physical poses, controlled breathing, and meditation or relaxation has been best known to reduce the implication of stress in increased production of inflammatory cytokines in gene expression, including interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF alpha), thus reducing the risk of inflammatory diseases.
And after examining the changes in gene expression that occur after MBIs and exploring how these molecular changes are related to health, through searching the database of published literature from PubMed throughout September 2016, research indicated that overall studies selected indicated an association of gene changes in yoga intervention was a result downregulation of nuclear factor kappa B pathway.
Furthermore, MBI practices may lead to a reduced risk of inflammation-related diseases, through the reduced effects of chronic stress on gene expression.
Most interestingly, in the assessed possible rapid changes in global gene expression profiles in the peripheral blood mononuclear cells (PBMCs) in healthy people who practiced either a comprehensive yoga program or a control regimen, researchers found that the SK&P program has a more rapid and significant greater effect on gene expression in PBMCs compared with the control regimen.
Peripheral blood mononuclear cells (PBMC) include lymphocytes (T cells, B cells, NK cells), monocytes, and granulocytes which play an important role in improving immune system cellular function in fighting against infection and inflammation, enhanced tissue regeneration, restored function due to injuring, .....
Truly, the impact of yoga in the protection of gene expression of the immune system may involve a complexity of simple gene regulatory networks (GRNs), including the gene expression in PBMCs and inflammatory cytokines
Taken together, Yoga intervention and related practices may have a profound effect on gene expression alterations through a complex network of simple gene regulation in the immune system.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.
Sources
(1) Regulation of gene expression by yoga, meditation and related practices: a review of recent studies by Saatcioglu F1(PubMed)
(2) Rapid gene expression changes in peripheral blood lymphocytes upon practice of a comprehensive yoga program by Qu S1, Olafsrud SM, Meza-Zepeda LA, Saatcioglu F.(PubMed)
(3) What Is the Molecular Signature of Mind-Body Interventions? A Systematic Review of Gene Expression Changes Induced by Meditation and Related Practices by Buric I1,2, Farias M1, Jong J1, Mee C3, Brazil IA1,2,4,5.(PubMed)
#FermentedCucumber Promotes the Healthy Colon by Its #Probiotic Activity, Researchers Reveal
Kyle J. Norton
Probiotics are good bacteria that not only balance the ratio of gut microbiota in the intestine but also react with other body systems to provide optimal health in the human.
The most common types of probiotics are lactobacilli (like Lactobacillus acidophilus and Lactobacillus GG), bifidobacteria (like Bifidobacterium bifidus), and some yeasts (like Saccharomyces boulardii).
Although all probiotics shared the same functions to improve the gastrointestinal microbiome community, different probiotics have different effects.
The most common probiotic foods are
* Yogurt, a dairy product made by fermenting milk is one of the best sources of probiotics. Epidemiologically, yogurt not only provides protein and calcium for the body but also enhances healthy gut bacteria.
Additionally, the fermented products also protect against osteoporosis, and irritable bowel disease, and aid digestion.
* Kefir.
Kefir is a fermented probiotic milk drink made from kefir grains Kefir or kephir similar to those of thin yogurt.
According to the article by By Megan Ware RDN LD, Kefir as a probiotic has been found to process a number of health benefits, including lowering blood pressure, cholesterol, and glucose, improved lactose tolerance, and stomach health, weight control and promoting wound healing.
More precisely,
* In immunity, probiotics stimulate the immune function against inflammatory immune disorders.
* In the digestive system, probiotics protect the gut against gastrointestinal diseases and non-gastrointestinal diseases. caused by the overexpression of bad bacteria.
* In metabolism, probiotics influence the nutrient extraction from the diet, thus reducing the risk of obesity and obesity complication.
* Neurologically, probiotics control brain insulin signaling and metabolite levels that play a critical role in neurobehaviors.
The cucumber plant is a species of Cucumis Sativus, belongings to the family Cucurbitaceae and native to Western Asia. It is a creeping vine with roots in the ground and grows up with the support of frames.
With an aim to find a natural compound with probiotic potential, researchers investigated 3 bacterial strains designated as 437F, 1630F, and 1020G were isolated from a traditional pickle.
According to the tested results, all strains showed high acid and bile tolerance and exhibited antagonistic activity against various pathogens.
The straits also demonstrated the antioxidant activity, auto- and co-aggregation ability on the surface hydrophobicity, and attachment capacity in the range of other well-known probiotic strains without inducing toxicity.
Dr.Talebi S, the lead scientist wrote at the end of the experiment, "With respect to their characteristics and safety aspect, these Bacillus species may have potential to consider as probiotics for animal and/or human applications".
In additional differentiation of the effect of fermented cucumber activity as probiotics, researchers examined a total of 38 strains that were isolated from the pickled samples.
According to the tested assays, all strains showed a significant resistance after incubation at pH 2.5 did not change markedly, above 90 % (10(9) CFU/mL) survival rate was observed.
More precisely, the strains also exhibited a high survival rate at pH 3.5 (>90 %), compared to all dead at pH 1.5 except four strains that could survive 90 min.
In bile salt solution incubation, at 0.2 %, the survival rates were 81-94 % after 24 h, compared to 59-94 % in 2 and 4 %.
Similar to the aforementioned study, the tested strains also exerted the auto- and co-aggregation ability on the surface hydrophobicity and attachment capacity.
Only four of the tested strains were excluded due to safety precautions, according to antibiotic resistance patterns and certain metabolic activities.
In other words, most tested strains isolated from the fermented cucumber process have the ability to improve the ratio of microbiota composition in the gut.
Taken altogether, fermented cucumber may be used as probiotics to improve human digestive health, pending the confirmation of the larger sample size and multicenter human study.
Intake of CuB in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Three novel Bacillus strains from a traditional lacto-fermented pickle as potential probiotics by Talebi S1, Makhdoumi A1, Bahreini M1, Matin MM1,2, Moradi HS. (PubMed)
(2) In vitro screening of selected probiotic properties of Lactobacillus strains isolated from traditional fermented cabbage and cucumber by Zielińska D1, Rzepkowska A, Radawska A, Zieliński K. (PubMed)
(3) Seven benefits of kefir By Megan Ware RDN LD. (Medical News Today)
Probiotics are good bacteria that not only balance the ratio of gut microbiota in the intestine but also react with other body systems to provide optimal health in the human.
The most common types of probiotics are lactobacilli (like Lactobacillus acidophilus and Lactobacillus GG), bifidobacteria (like Bifidobacterium bifidus), and some yeasts (like Saccharomyces boulardii).
Although all probiotics shared the same functions to improve the gastrointestinal microbiome community, different probiotics have different effects.
The most common probiotic foods are
* Yogurt, a dairy product made by fermenting milk is one of the best sources of probiotics. Epidemiologically, yogurt not only provides protein and calcium for the body but also enhances healthy gut bacteria.
Additionally, the fermented products also protect against osteoporosis, and irritable bowel disease, and aid digestion.
* Kefir.
Kefir is a fermented probiotic milk drink made from kefir grains Kefir or kephir similar to those of thin yogurt.
According to the article by By Megan Ware RDN LD, Kefir as a probiotic has been found to process a number of health benefits, including lowering blood pressure, cholesterol, and glucose, improved lactose tolerance, and stomach health, weight control and promoting wound healing.
More precisely,
* In immunity, probiotics stimulate the immune function against inflammatory immune disorders.
* In the digestive system, probiotics protect the gut against gastrointestinal diseases and non-gastrointestinal diseases. caused by the overexpression of bad bacteria.
* In metabolism, probiotics influence the nutrient extraction from the diet, thus reducing the risk of obesity and obesity complication.
* Neurologically, probiotics control brain insulin signaling and metabolite levels that play a critical role in neurobehaviors.
The cucumber plant is a species of Cucumis Sativus, belongings to the family Cucurbitaceae and native to Western Asia. It is a creeping vine with roots in the ground and grows up with the support of frames.
With an aim to find a natural compound with probiotic potential, researchers investigated 3 bacterial strains designated as 437F, 1630F, and 1020G were isolated from a traditional pickle.
According to the tested results, all strains showed high acid and bile tolerance and exhibited antagonistic activity against various pathogens.
The straits also demonstrated the antioxidant activity, auto- and co-aggregation ability on the surface hydrophobicity, and attachment capacity in the range of other well-known probiotic strains without inducing toxicity.
Dr.Talebi S, the lead scientist wrote at the end of the experiment, "With respect to their characteristics and safety aspect, these Bacillus species may have potential to consider as probiotics for animal and/or human applications".
In additional differentiation of the effect of fermented cucumber activity as probiotics, researchers examined a total of 38 strains that were isolated from the pickled samples.
According to the tested assays, all strains showed a significant resistance after incubation at pH 2.5 did not change markedly, above 90 % (10(9) CFU/mL) survival rate was observed.
More precisely, the strains also exhibited a high survival rate at pH 3.5 (>90 %), compared to all dead at pH 1.5 except four strains that could survive 90 min.
In bile salt solution incubation, at 0.2 %, the survival rates were 81-94 % after 24 h, compared to 59-94 % in 2 and 4 %.
Similar to the aforementioned study, the tested strains also exerted the auto- and co-aggregation ability on the surface hydrophobicity and attachment capacity.
Only four of the tested strains were excluded due to safety precautions, according to antibiotic resistance patterns and certain metabolic activities.
In other words, most tested strains isolated from the fermented cucumber process have the ability to improve the ratio of microbiota composition in the gut.
Taken altogether, fermented cucumber may be used as probiotics to improve human digestive health, pending the confirmation of the larger sample size and multicenter human study.
Intake of CuB in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Three novel Bacillus strains from a traditional lacto-fermented pickle as potential probiotics by Talebi S1, Makhdoumi A1, Bahreini M1, Matin MM1,2, Moradi HS. (PubMed)
(2) In vitro screening of selected probiotic properties of Lactobacillus strains isolated from traditional fermented cabbage and cucumber by Zielińska D1, Rzepkowska A, Radawska A, Zieliński K. (PubMed)
(3) Seven benefits of kefir By Megan Ware RDN LD. (Medical News Today)
#Phytochemical #Carotenoids Inhibit the Expression of Transcription Factor Associated with #Livercancer Progression, Researchers Say
Kyle J. Norton
Liver cancer is a medical condition caused by irregular cell growth in the liver tissue due to the alternation of the cell's DNA.
The liver is the largest internal organ located in the upper right portion of the abdomen, beneath your diaphragm and above your stomach.
Since the organ is a soft tissue with fewer nerves, most liver cancer patients are diagnosed in the later stage of cancer.
liver cancer remains the fifth most common malignancy in men and the eighth in women worldwide.
Hepatocellular carcinoma (HCC) is a common form of primary liver cancer.
According to the statistic, approximately 42,030 adults (29,480 men and 12,550 women) in the United States will be diagnosed with primary liver cancer in 2019 in the US.
Believe it or not, since 1980, the incidence of liver cancer has tripled. Between 2006 and 2015, the number of people diagnosed with the disease increased by approximately 3% annually.
The exact causes of liver cancer are not identified. However, epidemiologically, age, gender, geography, cirrhosis (severe scarring in the liver), and medical conditions such as diabetes and obesity are some of the most common prevalent factors associated with liver cancer developing.
Some researchers suggested the increased liver cancer incidence may be associated with the promotion of a high-fat diet over the past few decades.
Dr. VanSaun MN, the lead scientist wrote, "Chronic changes induced by the prolonged consumption of a high-fat diet alone culminate in the development of primary liver dysplasias".
And, "High-fat diet-induced steatosis, coupled with a splenic injection model of experimental liver metastasis using syngeneic MC38 colon cancer cells, resulted in an increased number of secondary tumor nodules and metastatic burden in steatotic livers. Metastatic nodules were associated with focal peritumoral areas of infiltrating inflammatory cells and associated apoptotic cell populations".
Carotenoids is a class of mainly yellow, orange, or red fat-soluble pigments, including lycopene and carotene, found abundantly in ripe tomato, pumpkins, carrots, corn, and daffodils.
In finding a potential ingredient for the treatment of liver cancer researchers examined the carotenoids' effects on hepatocellular carcinoma (HCC) progression.
According to the tested results of the delivery of siFOXC1 using novel carotenoid functionalized dendritic nanoparticles (CDN), the CDN not only displayed a markedly reduced toxicity profile but also achieved ∼90% FOXC1 knockdown.
In other words, the established delivery CDN inhibited the expression of transcription factor FOXC1 which has been found to induce hepatocellular carcinoma (HCC) progression.
Including carotenoids, the CDN achieves ∼18% greater delivery efficiency compared to treatments of particles with no carotenoid tagging.
Researchers after taking other factors into account said, "thereby emphasizing the role of carotenoid mediated cell internalization in the efficient delivery of CDN-siFOXC1 complex in liver cancer cells".
More precisely, using the aforementioned delivery system, carotenoids are more effective in the inhibition of liver cancer compared to oral injection.
Taken altogether, carotenoids may be considered a remedy for the prevention and treatment of liver cancer, pending the confirmation of the larger sample size and multicenter human study.
Intake of carotenoids in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Carotenoid Nanovector for Efficient Therapeutic Gene Knockdown of Transcription Factor FOXC1 in Liver Cancer by Misra SK1, Ray T2, Ostadhossein F1, Kim B2, Ray PS2, Pan D. (PubMed)
(2) High fat diet-induced hepatic steatosis establishes a permissive microenvironment for colorectal metastases and promotes primary dysplasia in a murine model by VanSaun MN1, Lee IK, Washington MK, Matrisian L, Gorden DL. (PubMed)
Liver cancer is a medical condition caused by irregular cell growth in the liver tissue due to the alternation of the cell's DNA.
The liver is the largest internal organ located in the upper right portion of the abdomen, beneath your diaphragm and above your stomach.
Since the organ is a soft tissue with fewer nerves, most liver cancer patients are diagnosed in the later stage of cancer.
liver cancer remains the fifth most common malignancy in men and the eighth in women worldwide.
Hepatocellular carcinoma (HCC) is a common form of primary liver cancer.
According to the statistic, approximately 42,030 adults (29,480 men and 12,550 women) in the United States will be diagnosed with primary liver cancer in 2019 in the US.
Believe it or not, since 1980, the incidence of liver cancer has tripled. Between 2006 and 2015, the number of people diagnosed with the disease increased by approximately 3% annually.
The exact causes of liver cancer are not identified. However, epidemiologically, age, gender, geography, cirrhosis (severe scarring in the liver), and medical conditions such as diabetes and obesity are some of the most common prevalent factors associated with liver cancer developing.
Some researchers suggested the increased liver cancer incidence may be associated with the promotion of a high-fat diet over the past few decades.
Dr. VanSaun MN, the lead scientist wrote, "Chronic changes induced by the prolonged consumption of a high-fat diet alone culminate in the development of primary liver dysplasias".
And, "High-fat diet-induced steatosis, coupled with a splenic injection model of experimental liver metastasis using syngeneic MC38 colon cancer cells, resulted in an increased number of secondary tumor nodules and metastatic burden in steatotic livers. Metastatic nodules were associated with focal peritumoral areas of infiltrating inflammatory cells and associated apoptotic cell populations".
Carotenoids is a class of mainly yellow, orange, or red fat-soluble pigments, including lycopene and carotene, found abundantly in ripe tomato, pumpkins, carrots, corn, and daffodils.
In finding a potential ingredient for the treatment of liver cancer researchers examined the carotenoids' effects on hepatocellular carcinoma (HCC) progression.
According to the tested results of the delivery of siFOXC1 using novel carotenoid functionalized dendritic nanoparticles (CDN), the CDN not only displayed a markedly reduced toxicity profile but also achieved ∼90% FOXC1 knockdown.
In other words, the established delivery CDN inhibited the expression of transcription factor FOXC1 which has been found to induce hepatocellular carcinoma (HCC) progression.
Including carotenoids, the CDN achieves ∼18% greater delivery efficiency compared to treatments of particles with no carotenoid tagging.
Researchers after taking other factors into account said, "thereby emphasizing the role of carotenoid mediated cell internalization in the efficient delivery of CDN-siFOXC1 complex in liver cancer cells".
More precisely, using the aforementioned delivery system, carotenoids are more effective in the inhibition of liver cancer compared to oral injection.
Taken altogether, carotenoids may be considered a remedy for the prevention and treatment of liver cancer, pending the confirmation of the larger sample size and multicenter human study.
Intake of carotenoids in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Carotenoid Nanovector for Efficient Therapeutic Gene Knockdown of Transcription Factor FOXC1 in Liver Cancer by Misra SK1, Ray T2, Ostadhossein F1, Kim B2, Ray PS2, Pan D. (PubMed)
(2) High fat diet-induced hepatic steatosis establishes a permissive microenvironment for colorectal metastases and promotes primary dysplasia in a murine model by VanSaun MN1, Lee IK, Washington MK, Matrisian L, Gorden DL. (PubMed)
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