Monday, 12 June 2023

#Healthyfood #MonofloralHoney Processes Anti- Human Immunodeficiency Virus #HIV-1 Activities, According to Studies

By Kyle J. Norton

Honey may have a profound effect in reducing the risk and treatment of HIV-1, some scientists suggested.
Human immunodeficiency virus HIV-1 is the most widespread type worldwide that can lead to acquired immunodeficiency syndrome (AIDS).

Acquired immunodeficiency syndrome (AIDS) is a chronic condition caused by the infection of the human immunodeficiency virus (HIV).

According to epidemiological studies, people who serval sexual partners are the most at risk of HIV infection.

However, the virus can also transmit through infected blood transfusion, and infected mother to children.

Most people infected by the HIV virus may experience symptoms of fever, muscle aches, and joint pain similar to those of influenza in the early stage of the viral attacks.

At the final stage of the infection, the virus can weaken the immune system to the point that causes the onset of AIDS and induces more severe symptoms including the general symptoms of cancers accompanied by soaking night sweats, recurring fever, and persistent white spots or unusual lesions on your tongue or in your mouth.

Dr. Seth C Kalichman and colleagues in the infectious team, in the concern of the risk of HIV in people with multiple sexual partners in the examining the 209 HIV-positive men and 291 HIV-positive women recruited conveniently from HIV/AIDS support groups and antiretroviral clinics found that 63% and 309 (62%) participants were currently sexually active, of whom 247 (80%) reported only one sex partner in the previous 3 months and 62 (20%) reported two or more partners during that time".

Although the use of a condom may have some protective effects in the prevention of HIV transmitting disease, however, the team said, "Steady sex partners of participants with multiple partnerships were significantly less likely to be protected by condoms than steady partners of individuals with only one sex partner".


Dangerously, in the final report, the team wrote, "Individuals with multiple sex partners were also significantly less likely to have disclosed their HIV status".

Honey is a miraculous product made by bees using nectar from flowers.

The rich golden liquid is considered healthy sweet food for replacing the use of white sugar and artificial sweetener.

On finding a natural ingredient or whole food for the inhibition of human immunodeficiency virus HIV-1 before they can cause acquired immunodeficiency syndrome (AIDS), researchers evaluated the anti-HIV-1 activity of eight different kinds of honey.

The tested Monofloral Iranian honey from eight floral sources was analyzed to determine their anti-HIV-1 activities as well as their effects on lymphocyte proliferation.

According to the quantitative polymerase chain reaction (PCR) assay and high pure viral nucleic acid kit, 6 out of 8 monofloral kinds of honey from Petro selenium sativum, Nigella sativa, Citrus sinensis, Zataria multiflora, Citrus aurantium, and Zizyphus mauritiana flowers exerted a significantly inhibitory HIV-1 activity at different doses.

The half-maximal effective concentration (EC50) values of 6 out of 8 monofloral kinds of honey are 37.5, 88, 70, 88, 105, and 5 µg/ml respectively.
The monofloral Iranian kinds of honey from Astragalus gummifer and Chamaemelum Nobile flowers had a weak anti-HIV-1 activity, compared to others.

The frequency and intensity of cluster of differentiation CD4 expression on Peripheral blood mononuclear cells (PBMC) increased in the presence of all honey types, an indication of immune activity.

Peripheral blood mononuclear cells (PBMC) are round nucleus peripheral blood cells consisting of lymphocytes (T cells, B cells, NK cells), and CD4 cells or T4 helpers play critical roles to send signals to other types of immune cells with a function to destroy invasive pathogens.

Treatment with monofloral kinds of honey from Z. multiflora and N. sativa also increased the CD19 markers for normal and neoplastic B cells
According to the spectroscopic analysis, monofloral kinds of honey from P. sativum, N. sativa, Z. multiflora, and Z. mauritiana flowers processed a potency to be anti-HIV-1 agents.

In in-depth differentiation, researchers showed that the inhibitory effect of methylglyoxal is higher in the late stage of HIV-1 infection.

The chemical compound found to exert the anti-HIV-1 activity was methylglyoxal.

Taken altogether, monofloral kinds of honey containing high amounts of the bioactive compound methylglyoxal may be considered a functional food for the prevention of HIV-1 infection and combined with the primary therapy for the treatment of AIDs.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca



Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) Anti-HIV-1 activity of eight monofloral Iranian honey types by Behbahani M1. (PubMed)
(2) Recent multiple sexual partners and HIV transmission risks among people living with HIV/AIDS in Botswana by Seth C Kalichman, Dolly Ntseane, Keitseope Nthomang, Mosarwa Segwabe, Odireleng Phorano, and Leickness C Simbayi. (PMC)

#Phytochemical #Carotenoids,in the Prevention and Reduction of #Cataracts and #AMD, Researchers Suggest

By Kyle J. Norton

The eyes are a complex optical system that allows us to see by reacting to light.
There are many factors that can cause eye problems that disturb the vision inclduing
* Severe, sudden eye pain
* Recurrent pain in or around the eye
* Persistent eye itching, burning, or a heavy discharge in the eyes
* Sudden change in vision
* Unusual, even painful, sensitivity to light or glare

* Swollen, and red eyes

Eye diseases may induce symptoms of hazy, blurred, or double vision, seeing flashes of light or sudden bright floating spots, seeing rainbows or halos around lights, and severe onset of floaters.

If you have one or more aforementioned symptoms, please check with your doctor to rule out the possibility of glaucoma, macular degeneration,...

Eye health is the process to keep the eye healthy regardless of problems. The Canadian Association of Optometrists suggested that you can improve your eye health with these 7 tips
* Always keep a distance at least 5-times the width of the TV
* Taking vision health foods in your diet daily
* Regular eye exams
* Quit smoking
* Take a break from your computer ( 20 seconds for 20 minutes of computer work)
* Wear your protective glass if needed
* See your optometrists immediately if you suddenly have eye irritation from allergies, inflammation, infection, or injury,

Carotenoids are a class of mainly yellow, orange, or red fat-soluble pigments, including lycopene and carotene, found abundantly in ripe tomatoes, pumpkins, carrots, corn, and daffodils.

Dr. El-Sayed M. Abdel-Aal, the lead scientist in the examine the health effects of eye health stated
* The efficacy of carotenoids in the improvement and enhancement of eye health was attributed to its bioactive compounds lutein and zeaxanthin, the yellow or orange color found in various common foods such as cantaloupe, pasta, corn, carrots, orange/yellow peppers, fish, salmon, and eggs.

* Lutein and zeaxanthin are important dietary carotenoids in preventing and reducing cataracts and AMD, according to the studies.

* Dietary carotenoids have been found to protect the eyes against the incidences of cataracts.

* Carotenoids protect the vision in the older population caused by aging eyes.

* The phytochemicals inhibited the ultraviolet light (up to around 380 nm) and blue light (400–500 nm high energy) that have been found to induce eye damage and vision problems.

* Intake of carotenoids regularly prevents vision oxidative stress, leading to the alternation of eye cells.

* Furthermore, the chemical compound also prevent free radical in the induction of lipid peroxidation polyunsaturated fatty acids associated with vision damage, particularly in AMD.

Moreover, in the population with AMD, the doctor also found that carotenoids protect the macular pigment density (MPD), macular pigment optical density (MPOD), and macular pigment (MP) against the onset of AMD.

Based on the findings, Dr. El-Sayed M. Abdel-Aal, the lead scientist wrote, "Global researchers have identified lack of lutein and zeaxanthin as dietary causes in cataract and AMD-related blindness".

And, "More research looking into the development of high-xanthophyll functional foods is essential in order to develop dietary strategies for the management of cataracts and AMD in particular for elderly people".


Taken altogether, carotenoids process a higher amount of lutein, and zeaxanthin may be considered a remedy for the protection of eye health, pending the confirmation of the larger sample size and multicenter human study.

Intake of carotenoids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Dietary Sources of Lutein and Zeaxanthin Carotenoids and Their Role in Eye Health by El-Sayed M. Abdel-Aal,1,* Humayoun Akhtar,1 Khalid Zaheer,2 and Rashida Ali. (PMC)
(2) Seven Tips for Good Eye Health by The Canadian Association of Optometrists

#Healthyfood #Lentils' #Lectin Inhibits the Risk of #ColonCancer in Vitros, Researchers Say

By Kyle J. Norton

Lentils with abundantly bioactive compounds may have a therapeutic and positive effect in reduced risk and treatment of colon cancer, some scientists postulated.

Lentil, a type of pulse and tiny legume that can be cooked quickly and rich in protein and fiber is a bushy annual plant of genus Lens to the Fabaceae family, native to the Middle East.

Colon cancer is a medical condition characterized by abnormal cell growth in the colon tissues. At the later stage, the cancerous cells can travel a distance away from the original site to infect other healthy tissues and organ cells.

The evaluation of lentils' effect on the risk of colon cancer was found to associate with certain mechanisms involving several different aspects.

In the study to compare whether lentil's bioactive micro- and macroconstituents in the protection of early onset of colon cancer with a chemopreventive agent in 60 weanlings Fischer 344 male rats, 4 to 5 weeks of age, randomly assigned to 6 groups (10 rats/group), 5 groups fed with lentils preparation of raw whole lentils (RWL), raw split lentils (RSL), cooked whole lentils (CWL), and cooked split lentils (CSL) and Raw soybeans (RSB; Glycine max), respectively plus AIN-93G+5% in each group and the control group (C) received AIN-93G diet, observation after injections of azoxymethane carcinogen at 15 mg/kg rat body weight per dose, showed that rats fed with lentils preparation expressed a strong implication in protection against colon carcinogenesis through reduction of total aberrant crypt foci numbers and increase of hepatic glutathione-S-transferases activities in compared to a control group.

Aberrant crypt foci (ACF) are colorectal polyps in the lining of the colon and rectum and are considered a marker of a stage preceding the development of cancer.

Liver glutathione S-transferases (GSTs) are a family of phase II detoxification enzymes with the function to protect our body against toxicity caused by chemical injection through liver detoxification.

Interestingly, in colon cancer cell line LS174T, lectins differentiated the cancer line into gland-like structures through activated anti-epCAM monoclonal antibody with function in the inhibition of epithelial cell adhesion molecule (EpCAM), a signaling receptor and activator of the Wnt pathway in passing signals into a cell through cell surface receptors in the expression on tumor-initiating cells.


Furthermore, differentiation of human colon cancer cell lines LS174T, SW1222, and HT29, lectins isolated from some vegetables also showed a significant effect in an inhibited proliferation of all the cell lines, particularly, Vicia faba agglutinin, the lectin presented in broad beans in stimulated differentiation of undifferentiated colon cancer cells through expression of epithelial cell adhesion molecule (epCAM) antibody observed by Western blots without affecting the expression of epCAM.

More importantly, in the analysis of another bean lectin in the expression of cytotoxic activity in colon cancer induced by 1,2-dimethylhydrazine (DMH) or azoxy-methane/dextran sodium sulfate (AOM/DSS) in animal models, rat treated with lectin extract after 6 weeks exhibited anti-cancer activity through significantly decreased early tumorigenesis triggered by DMH by 70%, but without any evidence of apoptosis.

Additionally, the application of lectin extract also reduced the number of aberrant cryptic foci generated by colon cancer-induced agents by 50%, an indication of decreased risk of early onset of colon cancer.

The efficacy of the bean extract lectin in exhibited antiproliferative and proapoptotic expression against colon cancer probably was attributed to decreasing the signal transduction pathway protein, protein kinase B (Akt), in regulated multiple cellular processes such as cell apoptosis, cell proliferation, and cell migration and increased caspase 3 activity in the induction of cancer apoptosis.

Taken together, although lectin isolated from beans and lentils inhibited colon cancer indirectly through undifferentiated colon cancer cell lines to differentiate into gland-like structures via expression of epithelial cell adhesion molecule (epCAM), intake of lectin in supplement form should be taken with care as lectin has been found to induce toxicity in some reports.


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months



Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.


Sources
(1) Vicia faba agglutinin, the lectin present in broad beans, stimulates differentiation of undifferentiated colon cancer cells by Jordinson M1, El-Hariry I, Calnan D, Calam J, Pignatelli M.(PubMed)
(2) Chemopreventive effect of raw and cooked lentils (Lens culinaris L) and soybeans (Glycine max) against azoxymethane-induced aberrant crypt foci by Faris MA1, Takruri HR, Shomaf MS, Bustanji YK. (PubMed)
(3) Lectin reactivities as intermediate biomarkers in premalignant colorectal epithelium by Boland CR1, Martin MA, Goldstein IJ. (PubMed)
(4) Phaseolus acutifolius Lectin Fractions Exhibit Apoptotic Effects on Colon Cancer: Preclinical Studies Using Dimethilhydrazine or Azoxi-Methane as Cancer Induction Agents by Ulisses Moreno-Celis 1,† ID , Josué López-Martínez 1,†, Alejandro Blanco-Labra 2 , Ricardo Cervantes-Jiménez 1 , Laura Elena Estrada-Martínez 1 , Alejandro Eduardo García-Pascalin 1 , María De Jesús Guerrero-Carrillo 1 , Adriana Jheny Rodríguez-Méndez 3 , Carmen Mejía 1 , Roberto Augusto Ferríz-Martínez 1,* and Teresa García-Gasca 1(MOLESCULES)

#Herbal #Turmeric May Be Used to Manage #JointDiscomfort and Treat Osteoarthritis (OA), According to Clinical Trials

By Kyle J. Norton

Osteoarthritis (OA) one of the most common forms of arthritis that affects over 25 25 million people in the United States is a chronic inflammatory disease of the joints due to wear and tear over time.
The characteristics of osteoarthritis are aching pain, stiffness, or difficulty in moving the joint or joints. The pain usually gets worse in a change of weather, at night, and in advanced diseases, the pain can occur even at rest.

Conventionally, treatment of osteoarthritis (OA) focuses on pain relief and improved physical function through pharmacological, nonpharmacological, and surgical treatments.

The most common risk factors associated with the onset of OA include genetic preposition, being overweight or obese, previous joint injury, and repetitive movements or injuries to joints (such as a fracture, surgery, or ligament tears).

However, most people with some of the risk factors have never developed the disease.

Dr. Sally Thomas, the lead scientist in the treatment of OA patients wrote, "As current treatment options in OA are very limited, OA patients would benefit greatly from some ability to self-manage their condition".

And, "For overweight/obese patients, weight reduction, ideally incorporating exercise, is paramount. The association between metabolic syndrome, type-2 diabetes, and OA risk or progression may partly explain the apparent benefit of dietary-lipid modification resulting from increased consumption of long-chain omega-3 fatty acids from oily fish/fish oil supplements. A strong association between OA and raised serum cholesterol and clinical effects in statin users suggests a potential benefit of reducing cholesterol by dietary means".

In other words, depending on the causes, patients may be recommended to a specific treatment.


Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.

The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, and wound healing agent, and for the treatment of flatulence, bloating, appetite loss, ulcers, eczema, inflammations, etc.

With an aim to find a potential compound for the treatment of osteoarthritis (OA), researchers examined the Curene®, a bioavailable formulation of turmeric anti-inflammatory properties.

The randomized, double-blind, placebo-controlled, parallel group included 50 subjects aged between 40 and 75 years who were suffering from unilateral or bilateral OA of the knee for greater than 3 months according to American College of Rheumatology (ACR) criteria.
The treatment group received 500mg Curene® once daily and the other group received a placebo.

According to the results from the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, Curene® treated group showed a statistically significant reduction of pain score compared to the placebo without inducing any adverse effects.

In other words, Curene® 500mg not only reduced pain, and stiffness but also improved physical functioning in subjects suffering from knee OA.

In order to reveal more information on turmeric anti-OA activity, researchers investigated LI73014F2 is a novel composition prepared from extracts of Terminalia chebula fruit, Curcuma longa rhizome, and Boswellia serrata gum resin in the inhibition of 5-Lipoxygenase (5-LOX).

Where activated enzyme 5-Lipoxygenase (5-LOX), has been found to induce pain in patients with OA.

A 90-day randomized, placebo-controlled double-blind study included 105 participants divided into three groups: placebo (n = 35), 200 mg/day of LI73014F2 (n = 35), and 400 mg/day of LI73014F2 (n = 35).

According to the results from tested assays obtained from the baseline (day 0) and on day 14 ± 3, 30 ± 3, 60 ± 3, and at the end of the study (day 90 ± 3), all doses of LI73014F2 conferred a substantial effect on pain relief, improved physical function, and quality of life in OA patients, compared to the baseline.

Dr. Karlapudi V, the lead scientist said, "preclinical and clinical data together strongly suggest that the herbal formulation LI73014F2 is a safe and effective intervention for management of joint discomfort, demonstrating efficacy as early as 14 days".

Based on the findings, turmeric processed a high amount of bioactive curcumin used alone or combined with other herbal medicines may be considered supplements for the treatment of osteoarthritis (OA), pending the confirmation of the larger sample size and multicenter human study.

Intake of turmeric as a supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca



Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
Osteoarthritis
(1) A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Safety and Efficacy of Curene® versus Placebo in Reducing Symptoms of Knee OA by Panda SK1, Nirvanashetty S2, Parachur VA3, Mohanty N4, Swain T. (PubMed)
(2) A Placebo-Controlled Double-Blind Study Demonstrates the Clinical Efficacy of a Novel Herbal Formulation for Relieving Joint Discomfort in Human Subjects with Osteoarthritis of the Knee by Karlapudi V1, Prasad Mungara AVV2, Sengupta K3, Davis BA4, Raychaudhuri SP. (PubMed)
(3) What is the evidence for a role for diet and nutrition in osteoarthritis? by Sally Thomas,1 Heather Browne,1 Ali Mobasheri,2,3,4 and Margaret P Rayman. (PMC)

#Anthocyanin-Rich Extracts Found in #Herbal #Bilberry Reduce the Risk of Vascular Diseases in Vivo, Researchers Say

By Kyle J. Norton

Vasoprotection is when substances including herbal and natural remedies are used to protect the integrity of the blood vessels.

Blood vessels are the tubular structure including a vein, artery, or capillary which carries the blood through the tissues and organs pumped by the heart.

There are 3 main types of blood vessel
* Arteries that deliver oxygen-rich blood from the heart to the tissues and organs of the body. Damage of arteries is found to induce coronary artery disease caused by narrowing or blockage of the coronary arteries due to plaques accumulated on the arterial wall.

* Veins that carry blood toward the heart. Chronic venous insufficiency (CVI) is a common condition associated with a disease of the veins that affects up to 20 percent of adults.

* Capillaries (the smallest blood vessels) have been found to induce systemic capillary leak syndrome (SCLS) is a rare acquired disorder.

Some researchers suggested that following a healthy diet accompanied by moderate exercise may have a substantial impact on the blood vessel's integrity.

Dr. Hanrui Zhang said, "Accumulating evidence suggests that inflammatory cytokine tumor necrosis factor-alpha (TNFα) plays a pivotal role in the dysregulation of macrovascular and microvascular function".

And, "Dietary supplements and exercise training decrease TNFαproduction and ameliorate TNFα-mediated pathological changes in vasculature. Thus, the inhibitory effects of dietary supplements and physical exercise on TNFα production and TNFα signaling may contribute to their vasoprotective properties".

Bilberry is a species of low-growing shrub in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.

The plant berry has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, psoriasis, diabetes, etc.

In finding a natural ingredient that processes vasoactive and vasoprotective properties, researchers examined the effects of anthocyanin-rich extracts prepared from chokeberry (Ck), bilberry (B), or elderberry (E). on reactive oxygen species (ROS) play a critical role in the impairment of nitric oxide-mediated vascular functions.

In Coronary arterial rings isolated from 64 pigs and incubated in sterile tissue culture media overnight, Ck and B, but not E, produced dose- and endothelium-dependent vasorelaxation.

In coronary vascular tone, endothelium-dependent vasorelaxation by other factors was not affected by exposure of rings to any extract at 0.05 mg total anthocyanins per liter for 5 or 30 min.

Furthermore, anthocyanin-enhanced extracts produce endothelium-dependent relaxation in porcine coronary arteries.
However, high doses of B exerted a significant protective effect against the alternation of coronary arteries induced by ROS with no impact on vasorelaxation to endogenous or exogenous NO.

Based on the findings, researchers wrote, "These results suggest that such extracts could have significant beneficial effects in vascular disease".

Taken altogether, bilberry-processed abundantly bioactive compound anthocyanin may be considered a functioning remedy for the prevention and treatment of vascular disease, pending the validation of larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca



Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Direct vasoactive and vasoprotective properties of anthocyanin-rich extracts by Bell DR1, Gochenaur K. (PubMed)
(2) Vasoprotection by Dietary Supplements and Exercise: Role of TNFα Signaling by Hanrui Zhang* and Cuihua Zhang. (PMC)

#Healthyfood #Cabbage and #BabySpinach Improve the DigestiveFunction Through Their Antioxidant and Anti-Inflammatory Activity.

By Kyle J. Norton

Gastrointestinal diseases are conditions of the digestive system associated with disorders involving the gastrointestinal tract, including the esophagus, stomach, small intestine, large intestine, and rectum.
The digestive system includes the gastrointestinal tract (GI), liver, pancreas, and gallbladder with a healthy function of breaking down food into nutrients and fluids for the body's needs.

There are many different types of gastrointestinal diseases, including irritable bowel syndrome (IBS), Crohn's disease, celiac disease, and lactose intolerance.

The most common causes of gastrointestinal diseases are bacterial or viral infection, inflammation, poor circulation of the intestines, muscle dysfunction, gallstones, stress, and particularly long-term use of anti-inflammatory drugs. However, gut microbiota, a community of microorganisms living in the gastrointestinal tract has been found to induce a significant effect on digestive health if imbalanced, including
* Reducing the function of gut microbiota to absorb the dietary nutrients of the digestive system, in nutrient metabolism,

* Reducing the function of gut microbiota in the inhibition of xenobiotics and drug toxicity by facilitating the excretion, in xenobiotic, and drug metabolism,

* Reducing the structural integrity of the gut mucosal barrier, leading to weakened epithelial cells' function to protect the intestine against invasive pathogens.

* Reducing the gut microbiota interaction with the immune system against inflammatory immune disorders and inhibiting the risk of gastrointestinal diseases and non-gastrointestinal diseases caused by overexpression of bad bacteria, in immunomodulation.

Conventional medicine used for the treatment of gastrointestinal disorders is depending on the disease that triggers the disorder. such as antibiotics for bacterial infection, and painkillers for stomach pain.

Cabbage is a species of Brassica oleracea belongings to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem that is crowded with a mass of leaves, usually green but in some varieties, it may be red or purplish.

On finding a natural compound for the improvement of digestive function in the absorption of nutrients, researchers examined the effects of co-digestion of a carotenoid-rich vegetable such as carrot, cherry tomato, or baby spinach with an anthocyanin-rich vegetable such as red cabbage
intestinal cellular bioaccessibility (cBAC).

According to the analysis of the chemical constituents, the tested vegetables processed the concentration of % cBAC of lutein was 0.23-1.42%, lycopene 0.07-0.39%, α-carotene 0.01-0.12% and β-carotene 0.03-0.61% respectively.

Furthermore, the co-digestion of the vegetables/salads resulted in synergy in cellular antioxidant activity compared to those without salad.

Moreover, cellular anti-inflammatory activity was also a significant increase in vegetable co-digestion compared to single vegetables alone.

Additionally, among the tested vegetables, baby spinach co-digested with red cabbage showed synergistic bioactivities in all tested assays.

In other words, the co-administration of vegetables work synergistically to provide higher improvement of digestive function compared to single vegetable through their antioxidant and anti-inflammatory activity.

Taken altogether, red cabbage may be considered a functional food for the promotion of digestive health, pending the confirmation of the larger sample size and multicenter human study.

Intake of turmeric as a supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca



Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Effects on intestinal cellular bioaccessibility of carotenoids and cellular biological activity as a consequence of co-ingestion of anthocyanin- and carotenoid-rich vegetables by Phan MAT1, Bucknall MP2, Arcot J. (PubMed)

High #Coffee Intake Increases the Risk of #Fracture and #Osteoporosis (OP), According to Clinical Trials

By Kyle J. Norton

Compared to herbal medicine, food therapy even takes longer to ease symptoms, depending to the stages of the treatment which directly address the cause of disease.

Epidemiological studies do not agree that coffee and coffee caffeine may have an increased risk of bone loss, inducing osteoporosis in healthy adults and menopausal women.

Coffee, becoming a popular and social beverage all over the world, particularly in the West, is a drink made from roast beans from the Coffea plant, native to tropical Africa and Madagascar.

A longitudinal population-based Swedish Mammography Cohort included 61,433 women born in 1914-1948, with follow-up from 1987 through 2008. returned questionnaires by participants showed insignificant effects of coffee consumption in correlated to bone loss inducing fracture of any type to 14,738 women, and 3,871 had a hip fracture.

According to the report, high coffee intake (≥4 cups daily) was associated with a 2%-4% lower bone density, and the risk of osteoporosis had a relative risk ratio of 1.28 compared to a low intake (<1 cup daily) group.
Dr. Hallström H, the lead author said, "High coffee consumption was associated with a small reduction in bone density that did not translate into an increased risk of fracture".

Furthermore, a cohort of 31,527 Swedish women aged 40-76 years at baseline in 1988, at the follow-up of 10.3 years, osteoporotic fractures is found in 3,279 cases proposed that the risk of high coffee intake((>330 mg/day) showed a moderated relative risk ratio of increased risk of fracture of 1.20 in compared to low coffee consumption(<200 mg/day).

More importantly, low calcium intake (<700 mg/day) also is found to associate with an increased risk of fracture with both high caffeine intake and coffee consumption.

According to the evidence, National Food Administration, the institute conducted the study opinionated that people drinking more than 4 cups of coffee equivalence to 330 mg may be at risk of fracture and osteoporosis, moderately.

Interestingly, 980 postmenopausal women aged 50 to 98 years (mean age, 72.7 years) participated between 1988 and 1991 in the determination of the risk association between lifetime intake of caffeinated coffee, in cup-years, to bone mineral density (BMD) of the hip and spine in postmenopausal women, long term coffee intake expressed a profound effect with statistically significant graded association with caffeinated coffee and decreasing BMD at both the hip and spine.

But this result was revered by those women, who drank at least one glass of milk per day during most of their adult lives.

The found evidence suggested that a high amount intake of coffee and caffeine may have a negative impact on the increased moderated risk of osteoporosis but the intake of calcium supplements or calcium-fortified milk or products may ease the concerns.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Long-term coffee consumption in relation to fracture risk and bone mineral density in women by Hallström H, Byberg L, Glynn A, Lemming EW, Wolk A, Michaëlsson K.(PubMed)
(2) Coffee, tea and caffeine consumption in relation to osteoporotic fracture risk in a cohort of Swedish women by Hallström H1, Wolk A, Glynn A, Michaëlsson K.(PubMed)
(3) Coffee-associated osteoporosis offset by daily milk consumption. The Rancho Bernardo Study by Barrett-Connor E1, Chang JC, Edelstein SL.(PubMed)