Cruciferous vegetables, The Potential Neuro-Protective Healthy Foods

By Kyle J. Norton

Neuroprotection is a process to preserve the neuronal structure and/or function against the death or gradual death of neurons, including the use of medicines and herbs.

In other words, neuroprotection protects the neuronal integrity against the reduction in the rate of neuronal loss over time inducing neurological disease, including neurodegenerative disease.

Neurological diseases are the medical conditions of brain disorder. Anything that involves the structural, biochemical or electrical abnormalities in the brain, spinal cord or other nerves, including brain damage are considered neuro diseases.

Neurodegenerative disease is the class of condition associated with the progressive loss of neuron occurred mostly in older adults, including dementia. The most common dementia in the US is Alzheimer`s disease (AD).

Alzheimer's disease is an irreversible, progressive brain disorder caused by the slowly lost of neuron in the brain that affects the memory and thinking skills and, eventually, the ability to carry out the simplest tasks as the disease progress into advanced stage.

According to the statistic, dementia affects over 47.5 million people worldwide, approximately 58 percent are living within low and middle-income countries.

Believe it or not, 5.8 million Americans of all ages are living with Alzheimer's dementia in 2019 and two-thirds of people with Alzheimer's disease are women.

Conventionally, as of today, there is no cure for dementia. Treatment of dementia is focusing to improve dementia symptoms and slow down the progression of the disease.

Cruciferous vegetables are a group of vegetables, belongings to the family Brassicaceae (also called Cruciferae) with many genera, species, and cultivated all over the world in suitable climate for commercial profits, including cauliflower, cabbage, kale, garden cress, bok choy, broccoli, Brussels sprouts, and green leafy vegetables.

On finding a potential compound for the treatment of neurological diseases, researchers examined cruciferous vegetable neuroprotective activity.

According to the dietary information,
* SFN, a potent bioactive compound found in the veggies upregulated the nuclear factor erythroid 2-related factor 2 (Nrf2) antioxidant response element (ARE) genetic pathway by increasing the antioxidant enzymes produced by the host.

* SFN was found to protect the nervous system from many diseases against and toxins in few small human trials.

* Furthermore, according to the preclinical data, SFN protected the nervous system through multiple mechanisms, reduced the risk of many diseases and the burden of symptoms in existing conditions.

In other words, SFN processed protective effects in a multitude of neurological diseases and toxin exposures.

Based on the evidence, researchers said, "SFN is a promising neuroprotective phytochemical which needs further human trials to evaluate its efficacy in preventing and decreasing the burden of many neurological diseases".

Taken altogether, cruciferous vegetables may be considered neuroprotective functional foods, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
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Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) The neuroprotective mechanisms and effects of sulforaphane by Klomparens EA1, Ding Y. (PubMed)

Herbal Dandelion(Taraxacum officinale) Inhibits the Parameters Involved in Hepatitis B Infection

By Kyle J. Norton

The liver is the largest internal organ found in the human which plays an essential role in filtering the blood from the digestive system before passing them to other parts of the body.

The liver also produces cholesterol, a waxy substance which aids digestion, builds cell membranes and produces vitamin D and steroid hormones.

Liver disease is a class of medical conditions characterized by the reducing partly or completely the function of the liver, including liver failure.

Hepatitis B is a liver disease caused by liver inflammation of viral Hepatitis C, leading to irreversible liver scars. Over time, the condition can also induce liver cancer.

The most common symptoms of liver disease are jaundice, abdominal pain and swelling, swelling in the legs and ankles, itchy skin, dark urine color, pale stool color, or bloody or tar-colored stool, chronic fatigue and nausea or vomiting.

According to the statistics from the WHO, in 2015, 257 million people were living with chronic hepatitis B infection (defined as hepatitis B surface antigen-positive). 

In 2015, hepatitis B resulted in an estimated 887 000 deaths, mostly from cirrhosis and hepatocellular carcinoma (i.e. primary liver cancer).

The most common risk factors associated with hepatitis B infection are unprotected sexual contact, sharing needles with someone infected by the virus.

sadly, a mother with hepatitis B infection also can transmit the disease to her child.

Dandelion is a herbaceous perennial plant, genus Taraxacum, belongings to the family Asteraceae, native to temperate regions of the world. It has been used in traditional and herbal medicine to treat gout, eczema, acne, gall bladder, kidney, liver and urinary disorders, hypoglycemia, dyspepsia with constipation, edema, blood pressure, and heart weakness, chronic joint, skin diseases, etc.

On finding a natural ingredient for the prevention and treatment of liver diseases, scientists examined the T. mongolicum extract (TME) antiviral effect against the hepatitis B virus (HBV).

According to the tested differentiation, in chemically-injured neonatal rat hepatocytes, DHBV-infected duck fetal hepatocytes and HBV-transfected HepG2.2.15 cells, TME at 50-100 µg/ml
* Inhibited the levels of  D-galactosamine (D-GalN), thioacetamide (TAA) and tert-butyl hydroperoxide (t-BHP)- associated with the injured hepatocytes in rat liver, induced the protection rates of 42.2, 34.6 and 43.8% at 100 µg/ml, respectively.

* TME at 1-100 µg/ml markedly inhibited DHBV DNA replication.

* TME at 25-100 µg/ml reduced HBsAg and HBeAg levels and produced inhibition rates of 91.39 and 91.72% at 100 µg/ml, respectively.

* TME markedly inhibited HBV DNA replication at 25-100 µg/ml.

Collectively, TME inhibited the parameters associated with the initiation of hepatitis B infection involved in the amelioration of oxidative stress.

Based on the findings, researchers said, "The antiviral properties of TME may contribute to blocking protein synthesis steps and DNA replication".

Taken altogether, Dandelion may be considered a remedy for the treatment of hepatitis B infection, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Taraxacum mongolicum extract exhibits a protective effect on hepatocytes and an antiviral effect against hepatitis B virus in animal and human cells by Jia YY1, Guan RF1, Wu YH1, Yu XP1, Lin WY2, Zhang YY1, Liu T3, Zhao J3, Shi SY2, Zhao Y. (PubMed)

Ursolic Acid, A Potential Adjunct Therapy for the Treatment of Lung Cancer

By Kyle J. Norton

The lung is a vital organ of the human being, located near the backbone on either side of the heart with functions of inhaling oxygen from the air then transporting them to the bloodstream to nourish the body cells' need and exhaling carbon dioxide from the bloodstream.

Lung cancer is defined as a condition of the abnormal growth of the cells in the lung's tissue.

A most common form of primary lung cancer is derived from epithelial cells. In the Us, Lung cancer causes the death of  158,683 people, including 88,329 men and 70,354 women, according to the 2007 statistic.

Believe it or not, each year, more people die of lung cancer than of colon, breast, and prostate cancers combined.

Most people diagnosed with lung cancer are 65 or older, compared to a very small number of those younger than 45.

Non-small cell lung cancer is the most common type of lung cancer. It usually grows and spreads methodically and predictably. 

Most common types of lung cancers include

* Squamous-cell carcinoma is a type of NSCLC often found in an outer area of the lung.

* Large-cell carcinoma is a type of NSCLC found in the center of the lung by an air tube.

* Adenocarcinoma is a type of NSCLC found in any part of the lung.

The 5 years of the survival rate of never and ever smokers in patients with stage I is 92%, compared to 76%, in smokers.

The 5-year recurrence-free proportions (RFPs) for never and ever smokers were 89% compared to 80%, in smokers.

Ursolic acid is a phytochemical in the subclass of Triterpenoid, belongings to the group of Terpenes found abundantly in apples, basil, bilberries, cranberries, peppermint, lavender, oregano, hawthorn, prunes., etc.

On finding a potential phytochemical for the treatment of chronic diseases, researchers examined the effect of ursolic acid (UA) on the stemness of non-small cell lung cancer (NSCLC) cells.

According to the analysis of the NSCLC cells with paclitaxel resistance (A549-PR) which exhibited a remarkably stronger stemness than the parental A549 cells,

* UA administration significantly reduced the stemness and paclitaxel resistance of A549-PR cells.

* UA inhibited the miR-149-5p/MyD88 signaling in the promotion of cancer cell resistance and responsible for UA-mediated effects on the stemness of A549-PR cells.

After talking about other factors into account, researchers said, "UA could attenuate the stemness and chemoresistance of NSCLC cells through targeting miR-149-5p/MyD88 axis".

Taken altogether, Ursolic acid may be considered adjunct therapies in the treatment of non-small cell lung cancer, pending to the confirmation of the larger sample size and multicenter human study.

Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) The miRNA-149-5p/MyD88 axis is responsible for ursolic acid-mediated attenuation of the stemness and chemoresistance of non-small cell lung cancer cells by Chen Q1, Luo J1, Wu C1, Lu H1, Cai S1, Bao C1, Liu D1, Kong J. (PubMed)

The Effects of Herbal Angelica on Myocardial Fibrosis in Vivo

By Kyle J. Norton

Fibrosis is a medical condition caused by the excessive formation of fibrous connective tissue in an organ or tissue.

Myocardial fibrosis is a medical condition caused by increased myofibroblast activity and excessive extracellular matrix deposition in the heart.

Myocardial fibrosis has been found to induce heart remodeling that leads to heart failure and death.

The severity of the grades range from A0 to A3:
A0: no activity
A1: mild activity
A2: moderate activity
A3: severe activity

and

The severity of fibrosis stages range from F0 to F4:
F0: no fibrosis
F1: portal fibrosis without septa
F2: portal fibrosis with few septa
F3: numerous septa without cirrhosis
F4: cirrhosis, the most severe stage of fibrosis
 

The most common symptoms of are myocardial fibrosis are increased myocardial stiffness, cardiomyocyte necrosis, arrhythmias, sudden cardiac death, and unfavorable prognosis.

The most common causes of myocardial fibrosis are coronary heart disease, aortic stenosis, and hypertension.

Aortic stenosis and hypertension also have been found to pressure overload of the left ventricle induced hypertrophy and interstitial fibrosis.

Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.

The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.

On finding a natural compound for the treatment of diseases associated with fibrosis, the researchers examined the effects of Radix Angelica Sinensis and Radix Hedysari ultrafiltration extract (RAS-RH) on cardiac fibrosis induced by a single dose of total body irradiation (TBI) at 8 Gy.

Based on the analysis,

* The control hearts exhibited less collagen and fibrosis compared to (TBI) treatment rats showed the increase in the serum levels of transforming growth factor β1 (TGF-β1) involved in cytokine expression and troponin-I (TnI) associated with the inhibition of blood vessel contraction.

* RAS-RH treatment mitigated these morphological injuries.

* RAS-RH also induced the apoptosis of primary rat cardiac fibroblasts after X- irradiation.

* Genes associated with the cellular proliferation of rat cardiac fibroblasts induced by TBI were all inhibited by the injection of RAS-RH.

Collectively, researchers said, "RAS-RH may potentially be developed as a medical countermeasure for the mitigation of radiation-induced myocardial fibrosis".

Taken altogether, Herbal Angelica used in a combination with other herbal medicines may be considered a decoction for the prevention of myocardial fibrosis, pending to larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) The effects of Radix Angelica Sinensis and Radix Hedysari ultrafiltration extract on X-irradiation-induced myocardial fibrosis in rats by Ma C1, Fu Z2, Guo H3, Wei H2, Zhao X2,
Li Y. (PubMed)

Cruciferous Vegetables Gobble Up Liver Cancer Cells

By Kyle J. Norton

The liver is one of the organs with a lack of nerve tissue, therefore liver cancer does not induce pain until the later stage.

Liver cancer is a medical condition characterized by cell growth irregularly in the liver tissue.

The causes of liver cancer are associated with the alternation of cells DNA that normally begins in the cells on the surface of the inner lining.

Liver cancer at the early stage no not cause any symptoms. However, at the advanced stage, liver cancer cells can cause a wide range of symptoms including jaundice, abdominal swelling and pain, and dark urine and white stool accompanied by the general symptoms of cancers such as unintended weight loss, loss of appetite, chronic fatigue and tiredness and gastrointestinal discomforts.

The most common cause of liver cancer is infected by the hepatitis virus. However, in North America, due to overexpression of overweight and obese of the population, liver cancer may be slowly progressed from nonalcoholic fatty liver disease through cirrhosis to liver cancer.

There is a number of risk factors other than those mentioned above associated with the onset of liver cancer such as male, ethnicity, hepatitis viral carriers.

According to the statistics provided by the Canadian Cancer Society, every year, approximately, 1,900 men and 580 women are diagnosed with liver cancer, causing the death of 950 men and 270 women.

In 2017, 2,500 Canadians were diagnosed with liver cancer and 1,200 Canadians died from liver cancer.

Compared to the early stage of other cancer, the 5 years survival rate in the early stage diagnosis is only 31% and 43% of people with liver cancer diagnosed at stage 0 and 1.

Cruciferous vegetables are a group of vegetables, belongings to the family Brassicaceae (also called Cruciferae) with many genera, species, and cultivated all over the world in suitable climate for commercial profits, including cauliflower, cabbage, kale, garden cress, bok choy, broccoli, Brussels sprouts, and green leafy vegetables.

On finding a potential compound for the treatment of cancer, researchers examined the effects of Isothiocyanates (ITCs), the phytochemicals derived from the breakdown of glucosinolates that exist in cruciferous vegetables against liver cancer cells.

In HepG2 cells, all ITCs reduced metabolic activity in each cell line, particularly in the compound phenylethyl-ITC.

Both dietary and synthetic ITCs were found to suppress the migratory and invasive potential of all cell lines.

Furthermore, chronic injection of dietary and synthetic ITCs also inhibited the cancer cell colony-forming capability and induced apoptosis.

Phenylethyl-ITC exposure resulted in a significant generation of reactive oxygen species to stimulate the expression of cytotoxicity in the cancer cell lines.

Collectively, researchers said, "These data highlight the potential advantages of utilizing ITCs to delay the carcinogenic process and the potential for dietary and synthetic ITCs to act as anticancer agents".

Taken altogether, Cruciferous vegetables may be considered functional foods for the prevention of liver cancer, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Natural and Synthetic Isothiocyanates Possess Anticancer Potential Against Liver and Prostate Cancer In Vitro by Crowley E1, Rowan NJ1, Faller D2, Friel AM. (PubMed)

Phytochemical Tocopherols in Reducing the Risk and treatment of Chronic Diseases

By Kyle J. Norton

Chronic diseases are medical conditions that last more than 3 months depending on the type of diseases.

In other words, chronic diseases generally cannot be prevented or cured by medication, nor do they just disappear.

According to the statistics, chronic diseases affect millions of people worldwide, leading to the death of 35 million people in 2005, including many young people and those in middle age.

The most common types of chronic diseases include cardiovascular diseases, stroke, cancer, chronic respiratory diseases, diabetes, and mental disorders.

In an inflammatory perspective, chronic inflammatory diseases are the results of the immune system response that can not kill off all infectious pathogens during the acute phase of infection, leading to the immune adaptation to the new change.

In some cases, chronic diseases also are caused by the immune system mistakenly attacking the bodily tissue, leading to low-grade inflammation such as rheumatoid arthritis.

The exacted causes of chronic diseases are not identified. Aging, unhealthy lifestyle such as excessive alcohol drinking smoking, poor diet, lack of physical activity are the most common risk factors associated with the onset of the disease.

According to the joint study led by Fordham University, chronic diseases are among the most prevalent and costly health conditions in the US, affecting over 133 million of the US population as many of them suffer from at least one chronic disease and the number is growing in the rapid rate.

Some chronic diseases such as cancer have been found to be the leading causes of hospitalization, long-term disability, reduced quality of life, and death.

Tocopherols are phytochemicals of which many have vitamin E activity, belongings to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.

On finding a potential phytochemical for the treatment of chronic diseases, researchers examined the effect of tocopherols on a number of health conditions.

According to the tested analysis, tocotrienol suppressed the mevalonate pathway responsible for cholesterol and prenylated protein synthesis against the formation of hyperlipidemia.

Furthermore, tocotrienol, also showed significant activity in the prevention or treatment of diabetes mellitus, osteoporosis, and cancer.

In Vivo and Vitro, tocotrienol shows promising effects in preventing or treating a number of chronic health conditions.

Taken altogether, tocopherols may be considered a functional food for the prevention and treatment of chronic diseases, pending to the confirmation of the larger sample size and multicenter human study.

Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Tocotrienol and Its Role in Chronic Diseases by Chin KY1, Pang KL2, Soelaiman IN. (PubMed)

Collard Greens Protects the Liver Against Hepatic Damage

By Kyle J. Norton

The liver is the largest internal organ found in the human which plays an essential role in filtering the blood from the digestive system before passing them to other parts of the body.

Liver disease is a class of medical conditions characterized by the reducing partly or completely the function of the liver, including liver failure.

Most common types of liver disease in the US are

* Hepatitis C (26%) is a liver disease caused by liver inflammation caused by viral Hepatitis C, leading to irreversible liver scars. Over time, the condition can also induce liver cancer.
and
* Alcoholic liver disease (21%) is a condition that caused long-term excessive alcohol drinking. It is known that years of alcohol abuse can cause the liver to become inflamed and swollen. Over time, it has been found to induce the formation of liver scars, known as cirrhosis. Cirrhosis is the final stage of liver disease.

According to the statistic, in the US, cirrhosis and other chronic liver diseases are common disease-related causes of death. Approximately 31,000 people in the U.S. die each year from cirrhosis.

Sadly, approximately, 3.5 to 4.6 million people in the U.S. are chronically infected with the hepatitis C virus.

Liver damage and disease can also be caused by long-term intake of certain medications, such as paracetamol and Illegal drugs such as cocaine-induced liver injury.

Symptoms of liver diseases include persistent jaundice and gastrointestinal discomforts, abdominal pain, and swelling, leg and ankles swelling, itching, and pale color of stool.

 
Collard Green is a species of Brassica Oleracea, belongings to the family Brassicaceae with unknown origin. Today, the plant is cultivated commercially for its thick, slightly bitter edible leaves.

On finding a potential plant that process liver protective activity researchers examined the preventive effects of I3C found in Brassica family vegetables, including Collard Greens against ethanol (EtOH)-induced liver injury.

In the well-established chronic-plus-binge alcohol exposure model, chronic treatment with I3C alleviated EtOH-induced liver injury and hepatocyte apoptosis, but not steatosis, by attenuating elevated oxidative stress.

In other words, I3C protected the liver against damage by decreasing levels of hepatic lipid peroxidation, hydrogen peroxide, CYP2E1, NADPH-oxidase, and protein acetylation associated with the onset of oxidative diseases.

The liver protective activity was found in the maintenance of mitochondrial complex I, II, and III protein levels and activities in oxidative phosphorylation.

Furthermore, hepatic proinflammatory cytokines involved in liver damage were also inhibited by the increasing production of antioxidant enzymes and decreasing free fatty acid release.

Based on the findings, researchers said, "Collectively, I3C prevented EtOH-induced liver injury via attenuating the damaging effect of ethanol on the gut-liver-adipose tissue axis. Therefore, I3C may also have a high potential for translational research in treating or preventing other types of hepatic injury associated with oxidative stress and inflammation".

Taken altogether, collard green may be considered a functional food for the prevention and treatment of liver damage, pending to the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Preventive effects of indole-3-carbinol against alcohol-induced liver injury in mice via antioxidant, anti-inflammatory, and anti-apoptotic mechanisms: Role of gut-liver-adipose tissue axis by Choi Y1, Abdelmegeed MA2, Song BJ. (PubMed)