Omega 3 Fatty Acids Decrease the Risk of Non-Alcoholic Fatty Liver Diseases

By Kyle J. Norton

Non-alcoholic Fatty Liver Disease is a condition of fatty liver diseases as a result of accumulated fat in the liver, not caused by abusive alcohol consumption.

Nonalcoholic fatty liver disease (NAFLD) is emerging as a widespread condition in the US, approximately 30% of the adult population are obese.

The disease is also manifested by steatosis, steatohepatitis, cirrhosis.

Obesity is associated linearly to the prevalent risk of nonalcoholic fatty liver disease (NAFLD).

The disease, in most cases, is asymptomatic, however, it has been seen to slowly progress to end-stage liver disease.

According to the statistics, the non-alcoholic fatty liver disease affects over 25% of the US population.

Epidemiological studies suggested that most cases of nonalcoholic fatty liver disease are found in obese and extremely overweight adults. However, people with diabetes, high cholesterol or high triglycerides are associated with the increased risk of the diseases. Truly, 75% of obese have steatosis and 20% to 35% have nonalcoholic steatohepatitis (NASH).

As of today, there is no effective treatment in patients with NAFLD, change of diet and lifestyle to induce weight loss are the most common nonmedical treatment conventionally for management of the disease.

Some researchers suggested that the cause of NAFLD may be associated with the promotion of the Western diet over the past few decades.

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the treatment of liver diseases, researchers examined the therapeutic benefit of omega-3 polyunsaturated fatty acids (ω-3 PUFAs) on the nonalcoholic fatty liver disease (NAFLD).

The pooled; meta-analyses were conducted using random-effect or fixed-effect models based on the search of databases of PubMed, Cochrane Library, Springer Link, China National Knowledge Infrastructure (CNKI), Wanfang, and Chinese Scientific and Technological Journal (VIP) databases for RCTs on oral ω-3 PUFA supplementation in patients with NAFLD.

According to the results of 18 studies involving 1424 patients, * ω-3 PUFAs exerted a significant benefit for liver fat, alanine aminotransferase, aspartate aminotransferase, γ-glutamyl transferase, the liver stress markers, triglycerides, insulin resistance, and glucose, compared to control.

* However, there was significant interstudy heterogeneity.

* Furthermore, subgroup and regression analyses showed no significantly clear methodologic discrepancy. and publication bias and serious adverse events were not detected.

Collectively, researchers said, "Our meta-analysis suggests that ω-3 PUFA supplementation may decrease liver fat and hepatic enzyme parameters".

Taken altogether, Omega-3 fatty acids may be considered a functional food for the prevention and treatment of non-alcoholic fatty liver diseases, pending to the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


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Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Omega-3 polyunsaturated fatty acid supplementation and non-alcoholic fatty liver disease: A meta-analysis of randomized controlled trials by Yan JH1, Guan BJ2, Gao HY1, Peng XE. (PubMed)

Ursolic Acid, The Promised Anti-Bacterial and Anti-Biofilm Phytochemical

By Kyle J. Norton

Infection is a condition caused by a harmful microbial invasion of the body tissues

Most cases of bacterial infection are treated with antibiotics. However, bacterias are very adaptable, overuse of antibiotics has been found to make them resistant to antibiotics.

Out of trillions of strains of bacteria in the world, only a few cause diseases in humans. Believe it or not, our gut contains trillion microorganisms, most of them are bacteria.

The most common symptoms of bacterial infection are redness and heat, swelling, fever, pain at the site of infection.

In severe cases, the patient may also experience symptoms of swollen lymph glands.

Most cases of bacterial infection are treated successfully if the types of bacteria that cause the infection are identified.

A biofilm is a system that can be adapted internally to environmental conditions by its inhabitants. In other words, biofilm-forming from bacteria is one of the common forms of bacterial infection affecting up to 80% of human bacterial infections.

In biology, biofilm used by the bacteria as a natural defense mechanism of bacteria to survive under harsh environments, by attaching to a solid surface in a large community, including the skin, teeth, and mucosa.

Bacterial initiates biofilm formation with an aim to greatly enhance survival in hosts and cause chronic infections, leading to long-term inflammation and tissue damages.

The formation of a biofilm of bacteria may go through 2 stages, the adhesion phase is the stage that the bacteria attached to the surface or accumulates on a surface, After the adhesion phase, the bacteria enter the colonial phase, where the bacteria continue to grow, leading to the formation of dense bacterial aggregates.

Ursolic acid is a phytochemical in the subclass of Triterpenoid, belongings to the group of Terpenes found abundantly in apples, basil, bilberries, cranberries, peppermint, lavender, oregano, hawthorn, prunes., etc.

On finding a potential phytochemical for the treatment of chronic infectious diseases, researchers examined the effect of UA on carbapenem-resistant Enterobacter cloacae (CREC).

According to the analysis,
* UA has a MIC of 0.1 mg/mL against CREC.

* UA treatment inhibited CREC growth and impaired membrane integrity of CREC cells, observed by the decrease in intracellular ATP level, pH, and membrane potential and distinctive deformation in cellular morphology. 

* UA exerted a significant antibacterial effect on biofilm formation of CREC and inactivated CREC cells within biofilms.

After talking about other factors into account, researchers said, "These findings reveal that UA has potent antibacterial and antibiofilm activity against CREC and, thus, can be used as a natural food preservative to reduce CREC-related infections".

Taken altogether, Ursolic acid may be considered adjunct therapies in the treatment of bacterial infection, pending to the confirmation of the larger sample size and multicenter human study.

Intake of Ursolic acid in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


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Ovarian Cysts And PCOS Elimination
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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Antibacterial and antibiofilm activity of ursolic acid against carbapenem-resistant Enterobacter cloacae by Qian W1, Li X2, Shen L2, Wang T2, Liu M2, Zhang J2, Yang M2, Li X2, Cai C. (PubMed)

Herbal Coltsfoot(Tussilago farfara) Protects the Neurons Against Enterovirus 71 (EV71) Infection

By Kyle J. Norton

A virus is a small infectious pathogen that can only replicate inside the cells of an organism, causing infectious diseases, including influenza and the common cold.

A viral infection that causes inflammation is a result of the proliferation of a harmful virus inside the body by injecting their genetic material into the cells.

The most common diseases associated with viral infection depending on the types of viruses, including common cold and flu are smallpox, hepatitis, measles, mumps, rubella, chickenpox, and shingles.

The most common symptoms of viral infection are runny or stuffy nose, sore throat, coughing, nasal congestion, sneezing, and fever.

Believe it or not, viral diseases have been found to induce major impact through morbidity, impairment of personal health, loss of time at work and school, and cost of medical care.

In infancy and children, viruses cause a relatively low fatality rate but with frequent episodes of illness.

Dr. Davis DJ in his report of viral infection wrote," Relatively few of the known viruses cause a significant number of deaths; influenza, childhood viral pneumonia, and hepatitis are the only viral diseases causing more than 1,000 deaths per year"

And "Data based on the National Health Interview Survey of the National Center for Health Statistics show that the common cold annually causes 35.6 acute illnesses per 100 persons".

Enterovirus 71 (EV71) is a virus that has been found to cause epidemics of severe neurological disease and hand, foot, and mouth disease in children, particularly in children under the age of five.

Coltsfoot(Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belonging to the family Asteraceae, native to Europe and Asia. The herb has been used over thousands of year to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches and obstruction in the nasal passage, etc.

On finding a potential compound for the treatment of Enterovirus 71 (EV71) infection, researchers examined the neuroprotective activity in the neuro-inflammatory disease of Tussilagone (TSL), isolated from the flower of buds of Tussilago farfara (Compositae).

On human foreskin fibroblast (CCFS-1/KMC) and human rhabdomyosarcoma (RD) cell line, a hot water extract of Flos Farfarae showed a significant effect in the inhibition of EV71 infection.

According to the plaque reduction assays and flow cytometry, Flos Farfarae inhibits EV71 infection by blocking viral replication and protein expression.

Based on the findings, researchers said, " Flos Farfarae could be beneficial to inhibit EV71 infection by preventing viral replication and structural protein expression".

Taken altogether, coltsfoot may be considered a remedy for the treatment of neuro diseases caused by Enterovirus 71 (EV71), pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Flos Farfarae Inhibits Enterovirus 71-Induced Cell Injury by Preventing Viral Replication and Structural Protein Expression by Chiang YW1, Yeh CF1, Yen MH2, Lu CY3, Chiang LC4, Shieh DE5, Chang JS. (PubMed)
(2) Measurements of the prevalence of viral infections by Davis DJ. (PubMed)

Angelica Sinensis, the Natural Depressant Remedy

By Kyle J. Norton

Depression is a common and serious psychological illness, affecting the physical and mental functions of patients, including the ways patients feel, think and act.

Some patients with depression may feel sadness and/or a loss of interest in activities once enjoyed.

There are many causes associated with the onset of depression, including genetics, changes in hormone levels, certain medical conditions, stress, grief or difficult life circumstances that initiate the change of brain chemistry in inducing depressive syndrome.

The most common symptoms of depression include sadness, hopelessness, guilt, change of mood, loss of interest in friends, family, favorite activities, and sex.

Some patients with depression also experience cognitive symptoms of trouble concentrating, making decisions, remembering and thoughts of harming themselves.

Readers may find other symptoms not be included in the article including behavior and physical symptoms.

Over 30 million Americans suffer from depression and the amount is increasing at an alarming rate. Depression may be a mental health disorder that can affect the way you eat, sleep, and the way you feel about yourself.

According to the statistics provided by the Anxiety and Depression of Association of American, major depressive disorder is the leading cause of disability in the U.S. for ages 15 to 44.3, affecting more than 16.1 million American adults, or about 6.7% of the U.S. population age 18 and older.

The mild case of depression can be defeated by a variety of self-care techniques. Others require the treatment of medication, such as antidepressant medications and psychotherapy that help to reduce and sometimes eliminate the symptoms of depression.

On finding a natural ingredient for the prevention and treatment of neurological disorders, scientists examined the effects of Xiaoyaosan (XYS), a famous and classic traditional Chinese prescription on depressive disorders.

Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.

The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.

In a total of 17 depressed patients and the 17 age- and gender-matched healthy subjects as the primary cohort, depressed patients were screened according to the Chinese Classification of Mental Disorder (CCMD-3) and the Hamilton Depression Scale (HAMD).

According to the results of experience,

* There were significant differences between depression cohort and healthy volunteers, and between patients before and after the treatment of XYS.

* Furthermore, XYS enhanced the levels of oxalic and stearic acids that significantly increased in depressed patients' plasma while valine and urea significantly decreased, as compared with healthy controls.

* XYS reversed these metabolite changes in terms of regulating dysfunctions in glyoxylate and dicarboxylate metabolism, fatty acid biosynthesis, valine, leucine and isoleucine biosynthesis, and arginine and proline metabolism.

Taken altogether, angelica sinensis may be considered a remedy to treat depression, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Plasma metabolomics of depressed patients and treatment with Xiaoyaosan based on mass spectrometry technique by Liu X1, Liu C1, Tian J1, Gao X1, Li K1, Du G2, Qin X. (PubMed)

Omega 3 Fatty Acid Inhibits the Onset of Fatal Coronary Disease in Cohosts

By Kyle J. Norton

Cardiovascular disease is medical conditions that affect the cardiovascular system, including heart, blood vessels(arteries and veins).

Coronary heart disease (CHD) is a condition of narrowing coronary arteries that lead to blockage of the blood flow in the arteries caused by hardening arterial wall, cholesterol building up in the arteries, chemicals, such as cadmium clog up arteries, etc. affecting the small blood vessels that supply blood and oxygen to the heart.

The acute coronary syndrome is a medical emergency caused by suddenly reduced blood flow to the heart, leading to heart muscle damage and brain apoptosis, depending on the affected location.

Plaque is made up of fat, cholesterol, calcium, and other substances found in the blood.

Arteries formed a part of blood vessels and circulatory system with function to deliver oxygen and nutrients to heart muscles.

According to the statistics, approximately 1 of every 13 Americans aged 18 years and older are living with coronary artery disease. CHD is a leading cause of death in the ethnic group in the US, particularly in Hispanic Americans.

Believe it or not, CHD is predicted by scientists to become the most common cause of death worldwide by 2020.

Although CHD is a lowly progressive disease, the disease may become clinically apparent by age 40. People 65 years of age and older have been found in most patients with CHD.

Depending on the severity of the blockage, a complete blockage is life-threatening. Symptoms of coronary artery disease, chest pain or discomfort, pain or discomfort in one or both arms, the jaw, neck, back or stomach, shortness of breath, dizziness, and nausea.

Coronary heart disease (CHD) is the leading cause of death in the United States.

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the treatment of heart diseases researchers examined the relationships between biomarkers of omega-3 fatty acids and risk for coronary heart disease (CHD).

,

According to the results of the study of the data10 of the cohorts,
* The overall mean (SD) for the Omega-3 Index in these 10 cohort studies was 6.1% (2.1%), and

* The HR for a 1-SD increase was 0.85 (95% confidence interval, 0.80-0.91).

* The median quintiles 1 and 5 levels were 4.2% vs. 8.3%, respectively.

* Based on these values, we estimate that the risk for fatal CHD would have been reduced by about 30% moving from an Omega-3 Index of 4%-8%.

Moreover, researchers said, "These findings support the use of <4% and >8% as reasonable therapeutic targets for the Omega-3 Index".

Taken altogether, Omega-3 fatty acids may be considered a remedy for the prevention and treatment of fatal coronary disease, pending to the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) The Omega-3 Index and relative risk for coronary heart disease mortality: Estimation from 10 cohort studies by Harris WS1, Del Gobbo L2, Tintle NL. (PubMed)

Herbal Dandelion(Taraxacum officinale) Treatment of Intestinal Metaplasia (IM) and Atypical Hyperplasia (AH)

By Kyle J. Norton

The stomach located between the esophagus and the small intestine is a muscular, hollow and important organ of the digestive tract.

The stomach plays a critical role in aiding the digestive system by secreting acid and enzymes that digest food induced by the stomach muscles that contract periodically, to churn the food and enhance digestion.

Atypical hyperplasia is a precancerous condition characterized by the accumulation of abnormal cells.

Intestinal metaplasia is a pre gastric cancer condition caused by the change of cells in the stomach.

The exact causes of the condition are unknown. However, some researchers suggested that smoking, and infection caused by H. pylori infection, genetic preposition and environment factors are some risk factors associated with the onset of intestinal metaplasia.

Gastric cancer is a medical condition characterized by irregular and uncontrollable cell growth in the stomach lining in the beginning. At the advanced stage, the malignant cells can travel a distance away through blood and fluid circulation to infect other healthy tissue and organs.

Researchers do not know why some people with the same health condition are susceptible to the risk of gastric cancer, while others do not. The exact causes of gastric cancer are also unknown. However, some researchers suggested that Age, diet, and stomach disease, such as can increase the risk of developing gastric cancer.

Both atrophic gastritis and gastric cancer share the common symptoms of stomach pain, nausea and vomiting, loss of appetite,... and indigestion. However, common symptoms of unexpected weight loss and stomach ulcers can only be found in gastric cancer while iron deficiency anemia is found in the majority of patients with atrophic gastritis.

According to the statistics provided by the American Cancer Society, in 2019, approximately, 27,510 cases of stomach cancer will be diagnosed (17,230 in men and 10,280 in women) and 11,140 people will die from gastric cancer (6,800 men and 4,340 women).

Overall, the 5-year survival rate for people with gastric cancer is 31%. Cancer diagnosed at the localized stage have a 5 years survival rate of 67%.

Dandelion is a herbaceous perennial plant, genus Taraxacum, belongings to the family Asteraceae, native to temperate regions of the world. It has been used in traditional and herbal medicine to treat gout, eczema, acne, gall bladder, kidney, liver and urinary disorders, hypoglycemia, dyspepsia with constipation, edema, blood pressure, and heart weakness, chronic joint, skin diseases, etc.

On finding a natural ingredient for the prevention and treatment of gastric diseases, scientists examined the efficacy of Xiao Wei Yan Powder (XWYP) decoction on intestinal metaplasia (IM) and 104 cases of atypical hyperplasia (AH).

Where  XWYP is a traditional Chinese Medicine formula containing Smilax glabrate, Hedyotis diffusae, Taraxacum mongolicum, Caesalpinia sappan, Paeonia alba, Cyperus rotundus, Bletilla striata, Glycyrrhiza uralensis, etc.

According to the results of 138 cases of intestinal metaplasia (IM) and 104 cases of atypical hyperplasia (AH) of the gastric mucosa of chronic gastritis that was treated by Xiao Wei Yan Powder (XWYP) orally 5-7g, for a period from 2-4 months, compared to control, the decoction showed a significant effect rate of IM was 91.3% and that of the AH was 92.16% compared to the control group of 21.3% and 14.46% respectively.

More precisely, XWYP not only had marked therapeutic effects for IM and AH but also showed no toxic effects in the animal experiments revealed no toxic effect,

These results strongly suggested that a safety guarantee was provided for its clinical application.

Taken altogether, Dandelion in a combination with other Chinese medicines may be considered a remedy for the treatment of intestinal metaplasia and atypical hyperplasia (AH), pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) [Treatment of intestinal metaplasia and atypical hyperplasia of gastric mucosa with xiao wei yan powder].[Article in Chinese] by Liu XR1, Han WQ, Sun DR. (PubMed)

Cabbage Processes Immunomodulatory Activity

By Kyle J. Norton

The immune system is the set of cells and their activity against antigens or infectious agents that comprise the body's defense system against diseases.

The immune system does a great job of keeping people healthy and preventing infections. Besides foods and nutritional supplements, herbs also play an important role in helping the immune system defend against viruses and bacteria attacks.

Immunomodulatory activity is an action that improves the underactive immune function that is susceptible to the invasion of the foreign microorganism and inhibits the overactive immune system that causes autoimmune diseases.

In other words, the immunomodulatory activity involved antimicrobial agents is to modulate the genes involved in immune reactions, or of the neurohormonal system which regulates immune functions and any toxic or immunotoxic effects such as allergic reactions or destruction of immune effectors, that may cause harm to the body or interfere with the body normal function.

The overactive immune system is a class of autoimmune diseases or chronic inflammatory diseases caused by the immune system attacking the body's tissue, including rheumatoid arthritis (RA), rheumatoid arthritis, systemic lupus erythematosus,.... and multiple sclerosis.

The widespread chronic inflammatory diseases in modern society are a burden to humans because of life-long debilitating illness, increased mortality and high costs for therapy and care.

The underactive or weakened immune system caused by a primary immune deficiency or acquired immune deficiency.may not protect the body against foreign organisms in initiated infection.

Sometimes, temporarily weaken the immune system may also be caused by the intake of certain conventional medicine, such as chemotherapy or drugs that treat cancer.

Cabbage is a species of Brassica oleracea belongings to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem with a crowded mass of leaves, usually green but in some varieties, it may be red or purplish.

On findings a natural wholefood for the improvement of immune functioning, researchers examined the immunomodulatory effect and mechanism of Lactococcus lactis A17 (A17), isolated from Taiwan fermented cabbage, on ovalbumin (OVA)-sensitized mice.

In live (A17-A) and heat-killed A17 (A17-H) orally administered to OVA-sensitized BALB/c mice effects, researchers found that  live (A17-A) and heat-killed A17 (A17-H) induced allergic effects by increasing the

* B-cell response that was modulated by diminishing IgE production and raising OVA-specific IgG2a production and the T-cell response that was modulated by increasing IFN-γ production and decreasing IL-4 production.

* Furthermore, the mRNA expression of NOD-1, NOD-2, and TLR-4 associated with the expression of inflammation and infection was down-regulated by A17.

In other words, a naïve Lactococcus lactis A17 strain exerted a significant immunomodulatory activity against allergic diseases via oral administration

Based on the results, researchers wrote, "the ameliorative effects of A17 may be caused by modulating NOD-1 NOD-2, and TLR-4 expression".

Taken altogether, cabbage processes immunomodulatory activity, pending to the confirmation of the larger sample size and multicenter human study.




Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Immunomodulatory Activity of Lactococcus lactis A17 from Taiwan Fermented Cabbage in OVA-Sensitized BALB/c Mice by Mei HC1, Liu YW, Chiang YC, Chao SH, Mei NW, Liu YW, Tsai YC. (PubMed)