Tuesday, 10 March 2020

Eyebright (Euphrasia), A Natural Antimicrobial Herbal Medicine

By Kyle J. Norton

The immune system is the set of cells and their activity against antigens or infectious agents that comprises the body's defense system against diseases. The immune system does a great job of keeping people healthy and preventing infections.

Besides foods and nutritional supplements, herbs also play an important role in helping the immune system defend against viruses and bacteria attacks.

Infectious diseases are a medical condition caused by pathogenic microorganisms, including bacteria, viruses, parasites or fungi.

Most cases of infectious diseases are contagious by spreading directly or indirectly, from one person to another.

In other words, if you kiss, or are coughed or sneezed on by an infectious person, you are at risk of developing the same infectious disease.

According to the statistic provided by the World Health Organization, 3 infectious diseases were ranked in the top ten causes of death worldwide in 2016.

More precisely, lower respiratory infections, diarrheal diseases, and tuberculosis induced 3.0 million, 1.4 million, and 1.3 million deaths, respectively.

Conventionally, most cases of infectious diseases except those caused by viruses are treated by antibiotics.

Microorganism, first observed by Anton van Leeuwenhoek in 1675 is a class of microscopic organisms, including a bacterium, virus, or fungus.

Believe or not, single-celled like bacteria, algae, and protozoa, or multicellular, such as algae and fungi can survive under all types of extreme environments.

And less than 1% of bacteria, can invade and cause infection and diseases.

Although the discovery of human antibiotics is medicines that kill or slow the growth of bacteria, however, overuses of the antibiotics have been found to induce microbial resistance to certain drugs.

On finding a natural ingredient for the prevention and treatment of infectious diseases, scientists examined the antimicrobial effects on the essential oil extracted from Eyebright, Euphrasia rostkoviana Hayne (Scrophulariaceae).

Eyebright is one of the species of flowering plants, genus Euphrasia, belonging to the family Orobanchaceae, native to Europe. 

The plant has been used in traditional and herbal medicine to treat eye infection and to relieve inflammation caused by colds, coughs, sinus infections, sore throats, and hay fever.

According to the analysis of eye infections induced by Enterococcus faecalis, Escherichia coli, Klebsiella pneumonia, Staphylococcus aureus, S. epidermidis, Pseudomonas aeruginosa, and Candida albicans,
* 70 constituents isolated from the essential oil that inhibited infection, the n-hexadecanoic acid (18.47%) was the main constituent followed by thymol (7.97%), myristic acid (4.71%), linalool (4.65%), and anethole (4.09%).

* The essential oil showed antimicrobial effect against all organisms tested with the exception of P. aeruginosa.

* Most importantly, the best activity was observed against all Gram-positive bacteria tested with the minimum inhibitory concentrations of 512 µg/mL.

Based on the results, researchers suggest, "This is the first report on the chemical composition of E. rostkoviana essential oil and its antimicrobial activity".

Taken altogether, Eyebright (Euphrasia) may be considered a remedy for the treatment of microbial infection, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Composition and Antimicrobial Activity of Euphrasia rostkoviana Hayne Essential Oil by Novy P1, Davidova H1, Serrano-Rojero CS1, Rondevaldova J2, Pulkrabek J3, Kokoska L. (PubMed)

Devil's Club Induces Human Ovarian Cancer Apoptosis in Vitro

By Kyle J. Norton

The ovaries are oval-shaped ovum-producing reproductive organ formed part of women reproductive system that connects to the fallopian tubes and attaches to the outer layer of the uterus via the ovarian ligament. Usually, the left and right ovary take a turn to release an egg every month.

Ovarian cancer is medical a condition characterized by abnormal cells growth of ovarian cells that start on the surface of the inner lining of the ovary. Over time, the oversized tumor can travel a distance away to infect the nearby organ and tissue via the fluid and blood circulation.

Most cases of ovarian cancer begin in the cells on the surface of the inner lining tissue of the ovary before spreading to the deeper layers to form a tumor.

In the very early stage, due to the very small size of the tumor, most patients are asymptomatic. However, as the disease progression, patients may experience symptoms shared commonly with other types of cancer accompanied by specific symptoms of abdominal bloating or swelling, discomfort in the pelvic area, changes in bowel habits, such as constipation.

According to the statistics, ovarian cancer is one of the fifth most common cancer, accounting for more deaths than any other cancer of the female reproductive system in the US.

The lifetime risk of getting ovarian cancer is about 1 in 78, compared to the lifetime of dying from ovarian cancer risk of 1 in 108.

The five-year relative survival rate for all types and stages of ovarian cancer is 47 percent, Cancer diagnosed at the early stage have a 5-year survival rate of over 72%.

The exact causes of ovarian cancer are not identified. However, epidemiological studies suggested that women who have endometriosis, genetic preposition such as BRCA1 and BRCA2 gene, acquired genetic mutation such as the TP53 tumor suppressor gene are susceptible to the substantial risk of the development of the disease.


Besides sharing the common symptoms of other types of cancer, most ovarian cancer patients may experience symptoms of discomfort in the pelvic area, changes in bowel habits, such as constipation. and a frequent need to urinate.

Devil's Club is a large shrub, genus Oplopanax, belonging to the family Aralioideae, native to the cool moist forests of western North America. 

The herb has been used in traditional and herbal medicine as Adaptogen, Antipyretic, Pain Reliever, Antitussive, Antibacterial agent and to treat Arthritis, Diabetes, Colds, Cough, Sore throat, Chest congestion, Stomach pain, Constipation, Gall stones, Influenza, Cancer, etc.

On finding a potential compound for the treatment of cancers, researchers investigated the Devil's club, effects on the ovarian cancer cells.

According to the results of Ovcar 10 two-dimensional cells grown as monolayer cells, and Ovcar 10 three-dimensional spheroids that were prepared with a rotary cell culture system,
* The application of tested herb showed an increased apoptosis-related gene expression in three-dimensional spheroids, compared to two- dimensional cells.

* Ovcar 10 three-dimensional spheroids were significantly more resistant to the killing by Devil's club extract, compared to two-dimensional cells, with IC50 levels closer to that observed in vivo.

* Furthermore, Devil's club extract and its active compound alone significantly enhanced the antiproliferation activity of cisplatin and gemcitabine at some concentrations, but did not affect the activity of paclitaxel.

* Moreover, in three-dimensional spheroids, the proportion of cells in the G2/M phase was slightly increased and the S phase was slightly decreased compared to two-dimensional cells.

Taken altogether, Devil's Club may be considered a remedy for the treatment of ovarian cancer, pending to the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Human ovarian cancer multicellular spheroids: a model for testing antiproliferation activity of Devil's club (Oplopanax horridus) and anticancer agents by Tai J1, Cheung SS2, Hasman D. (PubMed)

Herbal Ashwagandha in Post Stroke Management

By Kyle J. Norton

Stroke is a condition in which the brain function is interrupted rapidly due to the loss of blood supply as a result of the blockage of blood such as thrombosis and arterial embolism, or leakage of blood causes of the death of brain cells, according to the article of Mitochondria, oxidative metabolism and cell death in stroke by Sims NR, Muyderman H (September 2009).

In other words, stroke can be caused by either ischemia, due to lack of blood flow or hemorrhagic, due to bleeding.

A stroke is a medical emergency. Early intervention in most cases can minimize brain damage and potential complications.

There is a general belief that stroke is an accumulation over a long period of the unhealthy diet with red meat and processed meats in the induction of artery-clogging.

Some researchers suggested that increased intake of fruits and vegetables such as carrot accompanied with good fats such as salmon, tuna, and mackerel may have a substantial effect in reduced inflammation in the arteries, improved blood flow and decreased the chance of blood clots.

Sadly, stroke is one of the most common causes of death worldwide.

In the US, according to statistics, approximately 800,000 people suffer a stroke in which 600,000 of these are first attacks, and 185,000 are recurrent attacks. Nearly three-quarters of all strokes occur in people over the age of 65.

Stroke is also the third leading cause of death. Approximate 1/4 of all stroke victims die as a direct result of the stroke or its complications.

Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.

The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.

In the urgency to discover a natural ingredient for the prevention of disease associated with plaque accumulated on the arterial wall, researchers examined the effects of Withania somnifera (WS), supplementation on middle cerebral artery occlusion (MCAO) induced mitochondrial dysfunctions in an experimental model of ischemic stroke.

According to the tested analysis, before treatment with WS, tested mice showed an ischemia-reperfusion injury, leading to the increase of the oxidative stress indicated by increased reactive oxygen species and protein carbonyl levels and low levels of antioxidant enzymes.

The untreated mice also exerted decreased antioxidant enzymes superoxide dismutase and catalase activity, along with a reduction in GSH levels and the redox ratio, impaired mitochondrial functions and enhanced expression of apoptosis markers.

Ischemia-reperfusion injury in the tested mice also induced mitochondrial dysfunctions.

Moreover, the levels of pro-inflammatory and apoptotic proteins were also increased in the untreated mice.
The Y maze test also indicated a significant impairment in cognitive functions in the tested animal.

However, WS pre-supplementation ameliorated all parameters associated with the induction of MCAO such as oxidative stress, mitochondrial dysfunctions, apoptosis, and cognitive impairments.

Based on the evidence, researchers said, "WS pre-supplementation in ischemic stroke and are suggestive of its potential application in stroke management".

Taken altogether, Ashwagandha may be considered a supplement for stroke management, pending to the confirmation of the larger sample size and multicenter human study.



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Indian Ginseng (Withania somnifera) supplementation ameliorates oxidative stress and mitochondrial dysfunctions in experimental model of stroke by Sood A1, Mehrotra A1,2, Dhawan DK3, Sandhir R. (PubMed)

Monday, 9 March 2020

Herbal Elecampane (Inula helenium), Exerts Cytotoxic Effect on Cancer

By Kyle J. Norton

Genotoxicity is the term associated with chemical agents that damages the genetic information within a cell, causing mutations of cell DNA, a major cause of cancer.

Not all genotoxicity is mutagenicity, However, all mutagens are genotoxic.
Cytotoxicity is the process that induces cell death through toxins.

In other words, cell cytotoxicity is the process to use certain chemicals or mediator cells to destroy living cells.

In cancers, cytotoxicity can be benefits to humans by destroying the cancer cells and prevent them from proliferation.

However, cytotoxicity induced by oxidative stress due to the imbalanced ratio of free radicals and antioxidant enzymes produced by the body can cause protein, lipid and cellular damage that leads to chronic low-grade inflammatory diseases and cancer.

Stimulation of overexpression of free radicals and antioxidants production to induce cytotoxicity to the tumors can also cause cancer cell death without damage to nearby healthy cells.

Some researchers suggested that some plant pigment, including herbal medicine lipophilic secondary metabolites, process antioxidant properties in protecting healthy cells against cytotoxicity but also stimulating the expression of free radical cytotoxicity against cancer cells.

On finding a natural ingredient of the prevention and treatment of cancers, scientists examined the polyphenol fraction (IvE) isolated from Elecampane cytotoxic activities.
Elecampane, also known as Horse-heal (Inula helenium) is a perennial composite plant, genus nulla, belonging to Asteraceae, native to Southern Europe, and Asia. 

The plant has been used in traditional and herbal medicine in treating bronchitis or emphysema, night sweats, pulmonary tuberculosis, irritating cough, catarrhal discharges, etc.

According to tested analysis,
* Overall, forty-three secondary metabolites were identified, including the main components caffeic acid and unusual dihydro benzofuran lignans and cinchonain-type phenols, and hydroxycinnamoyl flavonol glycosides.

* The polyphenol fraction (IvE) showed strong antioxidant activity.

* Furthermore, the fraction inhibits cell viability and mitochondrial redox activity of neuroblastoma, hepatoblastoma, and colon carcinoma cells.

* Most importantly, IvE-induced increase of intracellular reactive oxygen species (ROS) to induce apoptosis without harming the healthy cells.

In other words, all phytochemicals found in the fraction work synergistically to exert cytotoxic and antioxidant activities against cancer cells.

Based on the results, researchers suggest, "The obtained results highlighted that inula leaves, nowadays even undervalued and unexplored, could be considered a renewable source of nutraceutical compounds.".

Taken altogether, Elecampane may be considered a remedy for the treatment of various types of cancer, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) A nutraceutical extract from Inula viscosa leaves: UHPLC-HR-MS/MS based polyphenol profile, and antioxidant and cytotoxic activities by Brahmi-Chendouh N1, Piccolella S2, Crescente G2, Pacifico F2, Boulekbache L3, Hamri-Zeghichi S3, Akkal S4, Madani K3, Pacifico S. (PubMed)

Elder (Sambucus) Processes Anti-Antiviral Infection Activity

By Kyle J. Norton

Infection is a condition caused by a harmful microbial invasion of the body tissues.

A viral infection is a disease caused by the successful entering and multiplying of a virus in the body.

Anti-viral effects are an act of certain substances to cause the destruction of a virus.

In the acute phase of viral infection, depending on the types of viruses, the viruses after entering the body start to attack the specific host cells. 

Similar to bacterial infection, both infections shared common characteristics by spreading through coughing and sneezing by and contact with infected people, especially through kissing and sex.

However, the virus may also cause infection by entering the body through wound and cut. Most viruses are killed in the acute phase of the infection.

During this phase, the immune system stimulates the constriction of blood vessels in speeding up the production of blood palette to cover the wound and production of inflammatory cytokines to the site of infection to fight off the bacterial and viral invasion.

The most common viruses that cause infection are hepatitis A, B, human papillomavirus (HPV) influenza. mumps, and rubella. People with a weakened immune system are susceptible to acute and chronic viral infections.

The cold and flu virus will attack the cells in the respiratory system and the human immunodeficiency virus (HIV), which causes AIDS, will attack the white blood cells of the immune system,

The viral infection has been known to carry over some different stage, after successfully attaching to the host cell, the virus to release its mRNA into the host cell, leading to the recruit of the host cell's enzymes to accelerate the viral multiplying, then breaking free from the host cell to start the cycle all over again.

The battle between the immune white blood cell and viral invaders in most cases an in the flavor of the side of the immune system, the invaders are killed and the infection is healed.

On finding a natural ingredient for the prevention and treatment of infectious diseases, scientists examined the antiviral activity of Sambucus FormosanaNakai ethanol extract on human coronavirus NL63 (HCoV-NL63).


Elder or Common Elder, is a shrub or small tree of the genus Sambucus of 30 species, belonging to the family Adoxaceae, native to the temperate-to-subtropical regions of both the Northern Hemisphere and the Southern Hemisphere.

The herb has been used in traditional and herbal medicine to treat constipation, colic, diarrhea, colds, flu, bronchial and upper-respiratory, irritation of the skin, rheumatism, etc.

According to tested analysis,
* The extract was less cytotoxic and concentration-dependently increased anti-HCoV-NL63 activities, including cytopathicity, sub-G1 fraction, virus yield (IC50 = 1.17 μg/ml), plaque formation (IC50 = 4.67 μg/ml) and virus attachment (IC50 = 15.75 μg/ml).

* Among the phenolic acid constituents in Sambucus FormosanaNakai extract, caffeic acid, chlorogenic acid, and gallic acid sustained the anti-HCoV-NL63 activity that was ranked in the following order of virus yield reduction: caffeic acid (IC50 = 3.54 μM) > chlorogenic acid (IC50 = 43.45 μM) > coumaric acid (IC50 = 71.48 μM).

* Caffeic acid significantly inhibited the replication of HCoV-NL63 in a cell-type independent manner and blocked the virus attachment (IC50 = 8.1 μM).


Based on the results, researchers suggest, "Sambucus Formosana Nakai stem ethanol extract displayed the strong anti-HCoV-NL63 potential; caffeic acid could be the vital component with anti-HCoV-NL63 activity. The finding could be helpful for developing antivirals against HCoV-NL63".

Taken altogether, Elder may be considered a remedy for the treatment of viral infection, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Antiviral activity of Sambucus FormosanaNakai ethanol extract and related phenolic acid constituents against human coronavirus NL63 by Weng JR1, Lin CS2, Lai HC3, Lin YP4, Wang CY4, Tsai YC4, Wu KC5, Huang SH6, Lin CW7. (PubMed)

Devil's claw (Harpagophytum procumbens) May Be Used for the Treatment of Migraine

By Kyle J. Norton

Migraine headache is one most common headaches associated with a condition of a chronic neurological disorder of moderate to severe headaches.

Nausea usually develops gradually over 5–20 minutes and lasts for less than 60 minutes.

According to the Research Migraine Foundation, nearly 1 in 4 U.S. households includes someone with migraines.

Approximately,  12% of the population suffers from migraines including 18% of American women, 6% of men, and 10% of children experience migraines. 

Migraine is most common between the ages of 18 and 44.

Sadly, 1 in 7 people in the world population will develop migraine headaches at some points in their lifetime. And, chronic migraine affects about 2% of the world population.

More precisely, if you are women your risk of migraine headache is 2 times higher in comparison to men.

Some patients during migraine attacks also suffer symptoms of visual disturbances, nausea, vomiting, dizziness, extreme sensitivity to sound, light, touch and smell, and tingling or numbness in the extremities or face.

Conventional medicine in reduced symptoms of pain during attacks such as Sumatriptan, Rizatriptan,..and Eletriptan may be effective but they may induce certain side effects, including gastrointestinal discomfort, dizziness, drowsiness,... and muscle weakness.

According to the International Headache Society, complications of migraine headaches can be divided into
* Chronic migraine
Chronic migraines are headaches in the absence of medication overuse, occurring on ≥15 days per month for ≥3 months, of which headaches on ≥8 days must fulfill the criteria for migraines and they continue over a long period of time.

*  Status migrainosus
Status migrainosus is a condition of migraine episodes that persist for less than 3 days, but in most cases, there are periods of relative relief, but these generally last no longer than four hours.

* Persistent aura without infarction (PAWI)
Persistent aura without infarction (PAWI) is a rare complication of migraines with neurological and ophthalmological examinations.

* Migrainous infarction
Migrainous infarction is a rare complication after the usual attacks of migraines with aura.

* Migraine seizures
A migraine seizure is an epileptic seizure that follows a migraine with aura, meeting the definition for migraine with aura, and an epileptic seizure must occur within one hour of the migraine aura.

On finding a natural ingredient for the prevention and treatment of headaches, scientists reviewed literature articles and relevant books using Web of Knowledge and SciVerse Scopus databases.
Devil's claw also known as the wood spider, is a plant of genus Harpagophytum in the family of Pedaliaceae, native to South Africa. 

The plant has been used as an herb in traditional and herbal medicine to treat fever, rheumatoid arthritis, skin, gallbladder, pancreas, stomach and kidneys conditions, etc.

According to tested analysis, devil's claw-derived compounds show considerable promise as novel drugs in migraine prevention and treatment.
However, their antimigraine action was unknown.

And its safety has not been determined.

Based on the results, researchers suggest, "It is necessary to conduct more research to better understand their antimigraine action, to confirm their effectiveness and safety, and to introduce them into clinical practice".

Taken altogether, Devil's claw a number of phytochemicals compounds may be considered a remedy for the treatment of migraine, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Natural products and their (semi-)synthetic forms in treatment of migraine: History and current status by Tauchen J. (PubMed)
(2)
Migraine Headaches - The Complications by Kyle J. Norton

Sunday, 8 March 2020

Herbal Enchinanea, A Promising Antioxidant and Anti-inflammatory Agent

By Kyle J. Norton

Infection is a condition caused by a harmful microbial invasion of the body tissues

Most cases of bacterial infection are treated with antibiotics. However, bacterias are very adaptable, overuse of antibiotics has been found to make them resistant to antibiotics.

Out of trillions of strains of bacteria in the world, only a few cause diseases in humans. Believe it or not, our gut contains trillion microorganisms, most of them are bacteria.

The most common symptoms of bacterial infection are redness and heat, swelling, fever, pain at the site of infection.

In severe cases, the patient may also experience symptoms of swollen lymph glands.

Most cases of bacterial infection are treated successfully if the types of bacteria that cause the infection are identified.

Antioxidants are stable atom that plays a critical role in protecting the body against the attack of free radicals.

In other words, antioxidants inhibited the onset of free radical before they can cause a chain reaction in facilitating the protein, lipid and cell damage.

Antioxidants can either produced by the liver or intake from dietary sources. Under normal conditions, antioxidant enzymes produced by the body in a healthy individual are good enough to counter the bombardment of free radical attacks.

However, in people with a weakened immune system, intake dietary sources of antioxidants may be necessary.


Echinacea also is known as purple coneflowers, is a flowering plant of the genus Echinacea, belongings to the family Asteraceae, native to eastern and central North America. The herb has been used in traditional and herbal medicine to treat or prevent colds, flu, infections by stimulating the immune function, etc.

On finding a potential phytochemical for the treatment of chronic infectious diseases, researchers examined Echinacea extracts anti antioxidant activities.

According to the analysis of the three Echinacea extracts which were labeled as A, B, and C (A, roots of Echinacea purpurea L. Moench; B, roots, leaves, flowers, and seeds of Echinacea purpurea; C, aerial parts and roots of Echinacea purpurea and roots of Echinacea Angustifolia DC),

* Extract C showed higher density (0.97 g/mL), dry matter (0.23 g/mL), phenols (137.5 ± 2.3 mEAG/mL), flavonoids (0.62 ± 0.02 mEQ/mL), and caffeic acid (0.048 mg/L) compared to A and B.

* A, B presented 11 alkylamides, whereas C presented those 11 and three more.

* B decreased edema (40%) on day 2 similar to indomethacin. A and C showed hypoglycaemic activity similar to glibenclamide.

* The antiproliferative effect was only detected for C (IC50 270 μg/mL; 8171 μg/mL; 9338 μg/mL in HeLa, MCF-7, HCT-15, respectively).

In other words, the roots of Enchinanea showed the highest antioxidant profiles and capacity compared to the other parts of the plant.

After talking about other factors into account, researchers said, "The difference in the chemical and pharmacological properties among extracts highlights the need to consider strategies and policies for standardization of commercial herbal extracts in order to guarantee the safety and identity of this type of products".

Taken altogether, herbal echinacea may be considered adjunct therapies in the treatment of diseases associated with chronic inflammatory diseases, pending to the confirmation of the larger sample size and multicenter human study.

Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Echinacea plants as antioxidant and antibacterial agents: From traditional medicine to biotechnological applications by Sharifi-Rad M1, Mnayer D2, Morais-Braga MFB3, Carneiro JNP3, Bezerra CF3, Coutinho HDM3, Salehi B4,5, Martorell M6, Del Mar Contreras M7, Soltani-Nejad A8, Uribe YAH9, Yousaf Z10, Iriti M11, Sharifi-Rad J. (PubMed)