Herbal Therapy: Topical Arnica Gel, Better Than Non-Steroidal Anti-Inflammatory Medications in Accelerated Ecchymosis Healing

Arnica may have a potential and therapeutic effect in reduced expression of Ecchymosis, some scientists suggested.

The results of these efficacy were confirmed by some studies conducted by numbers of respectable institutes, including University of Miami Miller School of Medicine and University of South Florida.

Ecchymosis is a condition of discoloration of the skin as a result of bleeding underneath. In most cases it is caused by bruising.

Arnica is a herbaceous species, genus perennial, belongings to the family Asteraceae, antive to Europe and Asia, used in herbal medicine for centuries to treat strains, sprains, and bruises.
Wound healing is process of repairing after damage of skin, tissues, organs, etc.

The ingredients
Helenalin, chamissonolid, Sesquiterpene lactone, lignans of the furofuran, dibenzylbutyrolactone, dibenzylbutyrolactol types, pinoresinol, epipinoresinol, phillygenin, matairesinol, nortrachelogenin, and nortracheloside, six dibenzylbutyrolactol derivative.


In order to confirm the effect of herbal Arnice activity in treatment of ecchymosis in patients who under went rhinoplasty, the most common facial plastic surgical procedure,  researchers at the joint study lead by the University of South Florida independently conducted a review of literature in databases (PubMed, SCOPUS, Embase, Web of Science, and the Cochrane database) from inception to September 2016, included studies that compared postoperative care methods (intervention groups) with no treatment (control group).

According to the final searching of 11 trials satisfied the criteria and guideline with a total of 627 patients, application of topical Arnica showed a significant effect in reduced eyelid ecchymosis during the first 7 days postoperative statistically in compared to the control group.

However, eyelid ecchymosis during the first 24 h postoperatively were statistically decreased in the cold compression group in compared to the control group.


Patients' questionnaires returned also expressed a strong satisfaction in the tapping application group than in the control group.

Also, the ratio of patient satisfaction was statistically higher in the tapping and Arnica application group than in the control group.

Additionally, the analysis also found that surgeons had a significant tendency to decrease intranasal packing in remove pain from the surgery area as the placement was found to associate with more adverse effects in terms of postoperative ecchymosis compared to non-packing.

Further differentiation to confirm the effectiveness of the combination of topical Arnica montana and Rhododendron tomentosum (Ledum palustre) in reducing postoperative ecchymosis in a select population of healthy volunteers after oculofacial surgery, researchers conducted a review examined the postoperative course of healthy volunteers using topical Arnica and Ledum after undergoing common oculofacial procedures, including blepharoplasty, browpexy, and rhinoplasty, in the hands of 4 surgeons at tertiary referral centers from July 1, 2012 to December 31, 2012 using medical records review.

A total of 27 patients (16 females, 11 males) with age range of 18 to 70 years were included in the study.

Selected medical review showed that patients included had used topical hydrogel pads (OcuMend, Cearna Inc., Chicago, IL) containing Arnica 50 M (10) 50% and Ledum 50 M (10) applied bilaterally after surgery through postoperative day 6 at each postoperative visit.

The results of everyday progression in patients were evaluated by their respective surgeons and assigned a subjective physician-patient rating score comparing each patient's observed healing compared with expected healing if not using Arnica/Ledum.

Photographs in each examination also were recorded.

The median duration of follow-up was 7 days, range from 1 to 14 days.

According to the rating of physician examined  the results, the proportions of patients with markedly accelerated healing were 38.5% (5 of 13), 85.7% (6 of 7), 60.0% (12 of 20), and 51.9% (14 of 27) at POD 1 to 2, 3 to 5, 6 to 8, and overall, respectively.

The proportions of patients with accelerated healing at the same time points were 15.4% (2 of 13), 14.3% (1 of 7), 30.0% (6 of 20), and 37.0% (10 of 27), respectively.

The proportion of patients using Arnica/Ledum with markedly accelerated healing was significantly more than the proportion of those demonstrating no appreciable difference from expected at (post operative day) POD 3 to 5 (85.7% vs. 0%, p = 0.05), POD 6 to 8 (60.0% vs. 10.0%), and overall (51.9% vs. 11.1%, p = 0.05) without inducing any adverse effects.

Dr. Lee HS, the lead author said, "The preliminary results from this study demonstrate that the combination of topical Arnica montana and Rhododendron tomentosum (Ledum palustre) may be effective in reducing postoperative ecchymosis....,after oculofacial surgery".

Taken together, topical Arnica may be considered as a functional food to accelerated the healing of ecchymosis

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA FOR WOMEN


Arthritis Is Curable

You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Sources
(1) Assessing the Effectiveness of Arnica montana and Rhododendron tomentosum (Ledum palustre) in the Reduction of Ecchymosis and Edema After Oculofacial Surgery: Preliminary Results by Kang JY1, Tran KD, Seiff SR, Mack WP, Lee WW.(PubMed)
(2) The effectiveness of postoperative intervention in patients after rhinoplasty: a meta-analysis by Lee HS1, Yoon HY1, Kim IH1, Hwang SH2.(PubMed)
(3) Is There a Role for Arnica and Bromelain in Prevention of Post-Procedure Ecchymosis or Edema? A Systematic Review of the Literature by Ho D1, Jagdeo J, Waldorf HA.(PubMed)

Herbal Therapy: Fennel, A Potent Chemo-Preventive and Modulatory Functional Herb

Kyle J. Norton

Fennel may have a potential and positive effect in modulated the effect of chemo drugs through its chemomodulatory activity, some scientists suggested.

The expression of fennel application in enhanced chemopreventive response was evident in animal models  from the reduced tumor burden in reduced cancer cells proliferation and apoptosis and reduced percentage of tumor through some different publications.

The results were reported by several respectable institute including Jawaharlal Nehru University and published on online medical literature.

Fennel (Foeniculum vulgare) is a plant species of genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean, used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...

Nutrients
1. Carbohydrates
2. Fiber
3. Protein
4. Thiamine (Vitamin B1)
5. Riboflavin (Vitamin B2)
6. Niacin (Vitamin B3)
7. Pantothenic acid (B5)
8. Vitamin B6
9. Folate (Vitamin B9)
10. Vitamin C
11. Calcium
12. Copper
13. Iron
14. Magnesium
15. Molybdenum
16. Phosphorus
17. Potassium
18. Zinc

According to the Jawaharlal Nehru University, in evaluate the chemopreventive effect of different doses of test diet of Foeniculum vulgare Mill (Fennel) seeds on DMBA-induced skin and B(a)P-induced forestomach papillomagenesis in Swiss albino mice, application of fennel seeds displayed a significant reduction in the skin and the forestomach tumor incidence and tumor multiplicity as compared to the control group.

Biochemical assays showed a significant increase in the content/activities of phase I and II enzymes especially in the case of 6% test diet, in detoxify poisonous compounds caused by injection of DMBA, through significant enhancement of antioxidant activities.

Further examination also found that injection of fennel seed stimulated production of antioxidant enzyme in the body tissue in repaired damage precipitated by peroxidation through lactate dehydrogenase activity.

Dr. Singh B, the lead author said, "A significant enhancement in the activities of antioxidant enzymes were observed especially at 4% and 6%" and "glyoxalase I(with function as enzymatic defence against glycation) activity and the content of reduced glutathione (antioxidant) were significantly elevated".

Additionally, in the examine the effect of fennel bioactive compound anethole in chemomodulatory activity against the onset and spread of cancer, researchers found that application of fennel oil by inhibited the activated expression of NF-kappa B, a gene-altering and inflammation in triggering molecule in development of various solid tumors through stimulated cancer proliferation.

Also, anethole injection reduced levels of tumor necrosis factor (TNF, tumor necrosis factor alpha, TNFα, cachexin, or cachectin), a cell signaling protein (cytokine) involved in systemic inflammation and one of the cytokines that make up the acute phase reaction. However, at a certain stage of cancer, gene expression in promoted cancer apoptosis is alternated,  TNF changes from a cancer killer to a cancer promoter.

Additionally, with abundant fiber, fennel demonstrated a strong effect in removal of toxins from the colon and therefore may be helpful in colon cancer prevention.

Dr. After taking into account of other co and confounders said, " Fennel contains flavonoid anti-oxidants compounds like kaempferol and quercetin which helps eliminate harmful free radicals from the body....".

In other words, fennel exerted chemomodulatory activity also through its flavonoid anti-oxidants compounds like kaempferol and quercetin in inhibited over expression of free radicals and free radical chain reactive in protected against cytotoxicity in induction cells damage and alternated cell DNA in facilitated onset of cancer.

Taking altogether, fennel and its bioactive compound may be considered as a chemo preventive and modulatory functional food for reduced risk and treatment of various types of cancers.

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA FOR WOMEN


Natural Medicine for Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Sources
(1) Chemomodulatory action of Foeniculum vulgare (Fennel) on skin and forestomach papillomagenesis, enzymes associated with xenobiotic metabolism and antioxidant status in murine model system by Singh B1, Kale RK(PubMed)
(2) Foeniculum vulgare Mill: A Review of Its Botany, Phytochemistry, Pharmacology, Contemporary Application, and Toxicology by Shamkant B. Badgujar,* Vainav V. Patel, and Atmaram H. Bandivdekar(PubMed)
(3) Arzoo and Milind Parle, Pharmacology Division, Department of Pharm. Sciences, Guru Jambheshwar University of Science and Technology(EUROPEAN JOURNAL OF PHARMACEUTICALAND MEDICAL RESEARCH)

Why You Should Eat Fennel At Least Once A Month to Detox Your Body, Public Medical Library Revealed

Kyle J. Norton


Fennel may have a potential and positive effect in excess water and toxin from body, some scientists suggested.


The result were reported on online medical literature conducted by some respectable institutes, including John Wiley & Sons, Ltd . and UFR Physiologie-Pharmacologie over different aspects via numbers of mechanisms.

Diuresis is a medicine in the stimulation of increased production of urine.


Fennel (Foeniculum vulgare) is a plant species of genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean, used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...


Nutrients
1. Carbohydrates
2. Fiber
3. Protein
4. Thiamine (Vitamin B1)
5. Riboflavin (Vitamin B2)
6. Niacin (Vitamin B3)
7. Pantothenic acid (B5)
8. Vitamin B6
9. Folate (Vitamin B9)
10. Vitamin C
11. Calcium
12. Copper
13. Iron
14. Magnesium
15. Molybdenum
16. Phosphorus
17. Potassium
18. Zinc
19. Etc.

In animal model, according to the John Wiley & Sons, Ltd. in the evaluation of the retoxic effect of ydroalcohol extracts of Foeniculum vulgare var dulce (D.C) root, application of the extract exerted a significant activities in flushing out of excess water and toxin from body through increased kidney function in secretion of the urine.

The result of these properties was observed by an increase in urine flow and urinary sodium excretion.

The efficacy in cleansing body was also found linearly in dose depending manner.

Continuously, in further examine the efficacy of fennel powder, extract and oil on gentamicin induced nephrotoxicity through an study of total 35 adult female sprague Dawley rats classified into five groups with first group kept on standard diet all over the period of the experiment. and the other groups administered gentamicin (100 mg/kg/day for 7 days i.p), followed by either control (+ve) group or treated groups with fennel powder, extract and oil for 45 days, at the end of study, researchers found that

* Injected gentamicin group served as control exhibited a strong nephrotoxicity manifested by increase levels of kidney function indicator, serum nitric oxide (NO) and kidney malondialdyde (MDA) however, this group of rats also exerted a significant decrease in weight gain.

Increased expression of serum nitric oxide (NO) and kidney malondialdyde (MDA) is an indicators of severed oxidative stress caused by imbalanced of ration of ROS and antioxidants in the host.

* Gentamicin groups treated with fennel powder, extract and oil demonstrated an improve the levels of urea and uric acid in comparing to control (+ve) and displayed an improvement of antioxidant enzymes as increase of serum superoxide dismutase(SOD), catalase, and glutathione transferase (GST) and decrease of serum NO in compared to control (+ve) group.

These results addressed the important antioxidant effect of fennel extracts. Applications not only inhibited the levels of free radical and theirs' chain reactive activities but also stimulated production of antioxidants found in the host tissue.

* Moreover, group treated with fennel oil restore the normal values of kidney antioxidant enzymes compared with normal group and other treatment groups.

Dr. Soheir Ahamed Al-Masri, the lead author, after taking into account of other co and con founders said, "fennel powder, extract and oil have a potent antioxidant and ameliorate in rats gentamicin induced nephrotoxicity in rats".

Clearly, fennel oil exhibited the greatest effect in stimulated kidney function in detox the body toxins through increased secretion of urine in compared to other experimental group.

The results of this study clearly indicate that fennel powder, extract and oil have a potent antioxidant and ameliorate in rats gentamicin induced nephrotoxicity in rats. [Soheir Ahamed Al-Masri and Waffa, Sh. Ali. The Ameliorating

Interestingly, in spontaneously hypertensive rats (SHR) treated with either water extract of Marrubium vulgare L. or Foeniculum vulgare L. in normotensive Wistar-Kyoto rats (WKY), researchers showed that application of fennel water extract reduced hypertension through Foeniculum increased water, sodium and potassium excretion in compared to non effect of Marrubium treated group.

Additionally, in compared to Marrubium extract in reduced hypertenion through inhibited contractile responses, fennel restored the normal; blood pressure by increased urine secretion and ameliorated the over expression of ROS and increased antioxidant status in the host.


Surely, one can says that Foeniculum acts mainly as a diuretic and a natriuretic while Marrubium displays vascular relaxant activity.

Taken together, fennel and its extracts may be considered as a detox functional food in getting rid of body toxins through its diuretic activities.


For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA FOR WOMEN

Natural Medicine for Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve Optimal Health And Loose Weight


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


Author Biography

Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Sources
(1) Diuretic action of hydroalcohol extracts oilFoeniculum vulgare var dulce (D.C.) roots in rats by
D. Beaux, J. Fleurentin and F. Mortier(Wiley Online Library)
(2) The Ameliorating Effects of Fennel Powder, Extract and Oil on Gentamicin Induced Nephrotoxicity in Rats 1 Soheir Ahamed Al-Masri and 2 Waffa, Sh. Ali( Journal of American Science)
(3) Pharmacological evidence of hypotensive activity of Marrubium vulgare and Foeniculum vulgare in spontaneously hypertensive rat by El Bardai S1, Lyoussi B, Wibo M, Morel N.(PubMed)

(2)

Food Therapy: Fennel and Its Extracts in Detoxed Body Toxins, According to PubMed Online Literature

Kyle J. Norton

Fennel may have a potential and positive effect in excess water and toxin from body, some scientists suggested.

The result were reported on online medical literature conducted by some respectable institutes, including John Wiley & Sons, Ltd . and UFR Physiologie-Pharmacologie over different aspects via numbers of mechanisms.
Diuresis is a medicine in the stimulation of increased production of urine.

Fennel (Foeniculum vulgare) is a plant species of genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean, used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...

Nutrients
1. Carbohydrates
2. Fiber
3. Protein
4. Thiamine (Vitamin B1)
5. Riboflavin (Vitamin B2)
6. Niacin (Vitamin B3)
7. Pantothenic acid (B5)
8. Vitamin B6
9. Folate (Vitamin B9)
10. Vitamin C
11. Calcium
12. Copper
13. Iron
14. Magnesium
15. Molybdenum
16. Phosphorus
17. Potassium
18. Zinc
19. Etc.


In animal model, according to the John Wiley & Sons, Ltd. in the evaluation of the retoxic effect of ydroalcohol extracts of Foeniculum vulgare var dulce (D.C) root, application of the extract exerted a significant activities in  flushing out of excess water and toxin from body through increased kidney function in secretion of the urine.

The result of these properties was observed by an increase in urine flow and urinary sodium excretion.

The efficacy in cleansing body was also found linearly in dose depending manner.

Continuously, in further examine the  efficacy of fennel powder, extract and oil on gentamicin induced nephrotoxicity through an study of  total 35 adult female sprague Dawley rats classified into five groups with first group kept on standard diet all over the period of the experiment. and the other groups administered gentamicin (100 mg/kg/day for 7 days i.p), followed by either control (+ve) group or treated groups with fennel powder, extract and oil for 45 days, at the end of study, researchers found that

* Injected gentamicin group served as control exhibited a strong nephrotoxicity manifested by increase levels of kidney function indicator, serum nitric oxide (NO) and kidney malondialdyde (MDA) however, this group of rats also exerted a significant decrease in weight gain. 

Increased expression of serum nitric oxide (NO) and kidney malondialdyde (MDA) is an indicators of severed oxidative stress caused by imbalanced of ration of ROS and antioxidants in the host.

* Gentamicin groups treated with fennel powder, extract and oil demonstrated an improve the levels of urea and uric acid in comparing to control (+ve) and displayed an improvement of antioxidant enzymes as increase of serum superoxide dismutase(SOD), catalase, and glutathione transferase (GST) and decrease of serum NO in compared to control (+ve) group.

These results addressed the important antioxidant effect of fennel extracts. Applications not only inhibited the levels of free radical and theirs' chain reactive activities but also stimulated production of antioxidants found in the host tissue.

*  Moreover, group treated with fennel oil restore the normal values of kidney antioxidant enzymes compared with normal group and other treatment groups.

Dr. Soheir Ahamed Al-Masri, the lead author, after taking into account of other co and con founders said, "fennel powder, extract and oil have a potent antioxidant and ameliorate in rats gentamicin induced nephrotoxicity in rats".

Clearly, fennel oil exhibited the greatest effect in stimulated kidney function in detox the body toxins through increased secretion of urine in compared to other experimental group.

The results of this study clearly indicate that fennel powder, extract and oil have a potent antioxidant and ameliorate in rats gentamicin induced nephrotoxicity in rats. [Soheir Ahamed Al-Masri and Waffa, Sh. Ali. The Ameliorating

Interestingly, in spontaneously hypertensive rats (SHR) treated with either water extract of Marrubium vulgare L. or Foeniculum vulgare L. in normotensive Wistar-Kyoto rats (WKY), researchers showed that application of fennel water extract reduced hypertension through Foeniculum increased water, sodium and potassium excretion in compared to non effect of Marrubium treated group.

Additionally, in compared to Marrubium extract in reduced hypertenion through inhibited contractile responses, fennel restored the normal; blood pressure by increased urine secretion and ameliorated the over expression of ROS and increased antioxidant status in the host.

Surely, one can says that Foeniculum acts mainly as a diuretic and a natriuretic while Marrubium displays vascular relaxant activity. 

Taken together, fennel and its extracts may be considered as a detox functional food in getting rid of body toxins through its diuretic activities.

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA FOR WOMEN


Arthritis Is Curable

You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half 

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Sources
(1) Diuretic action of hydroalcohol extracts oilFoeniculum vulgare var dulce (D.C.) roots in rats by
D. Beaux, J. Fleurentin and F. Mortier(Wiley Online Library)
(2) The Ameliorating Effects of Fennel Powder, Extract and Oil on Gentamicin Induced Nephrotoxicity in Rats 1 Soheir Ahamed Al-Masri and 2 Waffa, Sh. Ali( Journal of American Science)
(3) Pharmacological evidence of hypotensive activity of Marrubium vulgare and Foeniculum vulgare in spontaneously hypertensive rat by El Bardai S1, Lyoussi B, Wibo M, Morel N.(PubMed)
(2)

Researchers Found A Supplement in Inhibited Hair Loss and Promoted Hair Density In Women

Kyle J. Norton

Researchers may have a single ingredient for treatment of female hair loss pattern.

Supplementation with specific omega 3 & 6 and antioxidants acts efficiently against hair loss in improving hair density and reducing the telogen percentage and the proportion of miniaturized anagen hair.

Omega-3& 6 fatty acids are phytochemincals in the class of lipids, found abundantly in dark-green leafy vegetables, grains, legumes, nuts,...

Human have to absorb Omega 3 & 6 from other sources as we do not produce them.

In the total of 120 healthy female subjects participated in this 6-month, randomized, comparative study to evaluate the change in hair density on standardized photographs primary with. secondary endpoints to include changes in telogen hair percentage and diameter distribution of anagen hair (>40 µm vs. ≤40 µm) measured by trichogram, researchers found that intake of omega 3 & 6 and antioxidants display a significant effect in reduced hair loss and promoted hair growth.

According to the photograph assessment, the application demonstrated a superior improvement in hair density.

The telogen hair percentage was significantly (P < 0.001) reduced in the supplemented group.

The proportion of nonvellus anagen hair (>40 µm) increased compared to the control group.

Trichometer index in supplemented group expressed a substantial increment in compared to loss in control group.

At the end of the experience, Dr. Le Floc'h C, the led author said, "A large majority of supplemented subjects reported a reduction in hair loss (89.9% of subjects at 6 months), as well as an improvement in hair diameter (86.1%) and hair density (87.3%)".

Truly, the study of 6-month supplementation with omega 3&6 and antioxidants no doubt expressed a significant effect in inhibited hair loss and improved hair density and reduced telogen percentage and   miniaturized proportion of anagen hair.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources

(1) Effect of a nutritional supplement on hair loss in women by Le Floc'h C1, Cheniti A, Connétable S, Piccardi N, Vincenzi C, Tosti A.(PubMed)

Adding These Natural Sugars Instead of Commercial White and Brown and Sweeteners

By Kyle J. Norton

Can we replace daily commercial sugar intake by natural sources without dampening the taste? Yes, we can, but it may take a month or 2, before you can use to them.

The below are 2 very healthy sugar replacements with enormous health benefits



I. Honey
The rich golden liquid is the miraculous product made by bees using nectar from flowers. It is considered as one of healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.


Nutrients
1. Carbohydrates
2. Sugars
3. Protein
4. Water
5. Riboflavin (Vitamin B2)
6. Niacin (Vitamin B3)
7. Pantothenic acid (Vitamin B5)
8. Vitamin B6
9. Folate (Vitamin B9)
10. Vitamin C
11. Calcium
12. Iron
13. Magnesium
14. Phosphorus
15. Potassium
16. Sodium
17. Zinc
18. Etc.


A. Health benefits
A,1. health benefits according to studies
1. Acute cough in children
In the investigation of the effectiveness of honey for acute cough in children in ambulatory settings found that Dextromethorphan and honeydid not differ significantly on cough frequency (MD -0.49; 95% CI -1.15 to 0.17); cough severity (MD -0.50; 95% CI -1.28 to 0.29), bothersome cough(MD -0.29; 95% CI -1.14 to 0.56) and sleep quality of the children (MD -0.70; 95% CI -1.57 to 0.17) or their parents (MD -0.34; 95% CI -1.24 to 0.55) and concluded that we found insufficient evidence to advise for or against the use of honey for acute cough in children, according to "Honeyfor acute cough in children" by Oduwole O, Meremikwu MM, Oyo-Ita A, Udoh EE.(a)

2. Wound healing
In the assessment of Potential role of honeyon wound healing found that honey may improve healing times in mild to moderate superficial and partial thickness burns compared with some conventional dressings. Honey dressings as an adjuvant to compression do not significantly increase leg ulcer healing at 12 weeks. There is insufficient evidence to guide clinical practice in other areas. according to "Honey as a topical treatment for wounds" by Jull AB, Rodgers A, Walker N.(b)

3. Antiproliferative effect
In the identification of honey and its effect on keloid fibroblasts found that the methanolic honey extraction has an antiproliferative effect on keloid fibroblasts and a range of volatile compounds has been identified from Tualang honey. The antiproliferative effect of keloid fibroblasts towards Tualang honey may involve cell signaling pathway. Identifying other volatile compounds from different organic solvents should be carried out in future, according to "Antiproliferative effect of methanolic extraction of tualang honey on human keloid fibroblasts" by Nurul Syazana MS, Halim AS, Gan SH, Shamsuddin S.(c)

4. Antibacterial properties
In the classification of Honey possesses therapeutic potential on antibiotic resistance of bacteria
found that Tualang honey exhibited variable activities against different microorganisms, but they were within the same range as those for manuka honey. This result suggests that tualang honey could potentially be used as an alternative therapeutic agent against certain microorganisms, particularly A. baumannii and S. maltophilia, according to "The antibacterial properties of Malaysian tualang honey against woundand enteric microorganisms in comparison to manuka honey" by Tan HT, Rahman RA, Gan SH, Halim AS, Hassan SA, Sulaiman SA, Kirnpal-Kaur B.(d)

5. Anti-inflammatory and antioxidant effects
In assessment of Tualang honey and its anti-inflammatory and antioxidant effects found that Tualang honey has almost the equal effects when compared with the conventional treatment in treating alkali injury on rabbit's eye. Future research with more number of rabbits and control group is warranted to explore the anti-inflammatory and antioxidant effects of Tualang honey, according to "Anti-inflammatory and antioxidant effects of Tualang honey in alkali injury on the eyes of rabbits: experimental animal study" by Bashkaran K, Zunaina E, Bakiah S, Sulaiman SA, Sirajudeen K, Naik V.(e)

6. Etc.

A.2. Health benefits according to concentration
Energy
Honey contains high amount of glucose and fructose that are simple sugar (monosaccharide) played an important role to enhance energy production in carbohydrate metabolism, as they
are absorbed by the body quickly through insulin and potassium.

A.3. Other health benefits
1. Antiseptic and antibacterial properties
Recently research study that honey have the antiseptic and antibacterial properties as it increases the immune system in fighting the forming of free radicals causes of inflammation and infection causes of infection due to enzyme glucose oxidase, according to the study of `Antibacterialproperties of tualang honey and its effect in burn wound management: a comparative study`by Nasir NA, Halim AS, Singh KK, Dorai AA, Haneef MN., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/20576085), researchers found that Tualang honey has a bactericidal as well as bacteriostatic effect. It is useful as a dressing, as it is easier to apply and is less sticky compared to Manuka honey. However, for Gram positive bacteria, tualang honey is not as effective as usual care products such as silver-based dressing or medical grade honey dressing.

2. Diabetes chronic wound
External used is proven to be effective for treating diabetes chronic wound that antibiotic can not be used, according to the study of `Safety and efficacy of a new honey ointment on diabetic foot ulcers: a prospective pilot study`by Abdelatif M, Yakoot M, Etmaan M., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/18376651, researchers indicated that Ninety-six per cent of the patients in groups 1 and 2 responded well, with a complete cure, defined as'complete closure of the ulcer without signs of underlying bone infection' by the end of week 9 and for the duration of the six-month follow-up period. All of the ulcers in group 1 healed, as did 92% of those in group 2. All patients in group 3 healed following surgical excision, debridement of necrotic tissue and conservative treatment with PEDYPHAR ointment.

3. Phosphorus
Beside providing strength to bones and teeth by working together with calcium according to the study of `[The effect of one year therapy with recombinant human growth hormone (rhGH) on growth velocity, calcium-phosphorus metabolism, bone mineral density and changes in body composition in children with growth hormone deficiency (GHD)].[Article in Polish]`by Zak T, Basiak A, Zubkiewicz-Kucharska A, Noczyńska A., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/20529605), it also works with riboflavin and niacin to improve the digestive system in absorbing vital nutrients.

4. Iron and iron deficiency anemia
Iron is essential for the production of red blood cells and carrying life-giving oxygen to human cells. Deficiency of iron causes anemia, anemia of chronic disease, cough, anemia in pregnancy, etc., leading to reducing blood flow to the reproductive organ according to the study of `The effects of iron deficiency on estradiol-induced suppression of erythropoietin induction in rats: implications of pregnancy-related anemia` by Horiguchi H, Oguma E, Kayama F., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/15784734)


B. Side effects1. Because of the presence of botulinum endospores, children under one year of age should not be given honey
2. Honey may be poison if produced from the flowers of oleanders, rhododendrons, mountain laurels, sheep laurel, and azaleas etc.
3. It may contain traces of heavy metals, pesticides, etc.

II. Blackstrap Molasses
Molasses is the juice is boiled to concentration which promotes the crystallization of the sugar, made by extracting from the canes, usually by crushing or mashing, after the sugar cane plant is harvested and stripped of its leaves. The concentration of this first boiling and of the sugar crystals is first molasses, which has the highest sugar content.
Blackstrap molasses is the third boiling of the sugar syrup with of sucrose from the original juice has been crystallized and removed.


Nutrients

1. Glucose
2. Fructose
3. Biotin
4. Calcium
5. Potassium
6. Chloride
7. Manganese
8. Selenium
9. Copper
10. Iron
11. Magnesium
12. Potassium


A. Health benefits
A.1. Health benefits according to studies
1. Antioxidant
In the investigation of raw cane sugar, plant saps/syrups (eg, maple syrup, agave nectar), molasses, honey, and fruit sugars (eg, date sugar) and the total antioxidant content of natural sweeteners found that ark and blackstrap molasses had the highest FRAP (4.6 to 4.9 mmol/100 g), while maple syrup, brown sugar, and honey showed intermediate antioxidant capacity (0.2 to 0.7 mmol FRAP/100 g). Based on an average intake of 130 g/day refined sugars and the antioxidant activity measured in typical diets, substituting alternative sweeteners could increase antioxidant intake an average of 2.6 mmol/day, similar to the amount found in a serving of berries or nuts, according to "Total antioxidant content of alternatives to refined sugar" by Phillips KM, Carlsen MH, Blomhoff R.(a)

2. Vibrio furnissii M1
In the observation of "Production of alternatives to fuel oil from organic waste by the alkane-producing bacterium, found that Crude blackstrapmolasses were also converted into alkanes with a conversion ratio of 20% (half of that in an authentic sucrose medium) of the total carbon consumption, according to "Production of alternatives to fuel oil from organic waste by the alkane-producing bacterium, Vibrio furnissii M1" by Park MO, Heguri K, Hirata K, Miyamoto K.(b)

3. Microbial production
In the observation of microbial production of fermentation of blackstrapmolasses
found that A two-stage fermentation process was developed for the conversion of sugar or molasses of various types to propionic acid and vitamin B12. By fermentation of blackstrap molasses (from sugar beet and sugar cane) in the first fermentation stage 17.7 g propionic acid l-1 with a yield of 0.5 g propionic acid g-1 carbohydrate was produced with a dilution rate of 0.25 h-1. In the second stage 49 mg vitamin B12 1-1 was produced at a dilution rate of 0.03 h-1.(c)


A.2. Health benefits according to concentration
1. Manganese
Beside it is important in forming connective tissues and building of essential enzymes for building healthy bones, manganese also helps in regulating the normal function of of thyroid growth hormone, according to the study of "The effect of manganese supply on thyroid hormonemetabolism in the offspring of manganese-depleted dams" by Eder K, Kralik A, Kirchgessner M., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/8971361) and blood sugar level, according to the study of "Manganese corroles prevent intracellular nitration and subsequent death of insulin-producing cells" by Okun Z, Kupershmidt L, Amit T, Mandel S, Bar-Am O, Youdim MB, Gross Z., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/19715343)

2. Copper and Iron
Copper plays a role in a wide range of physiological processes, such as iron utilization of enhancing the hemoglobin. and reduction of malabsorption syndrome. according to the study of "Beneficial effect of goat milk on nutritive utilization of iron and copper in malabsorption syndrome" by Barrionuevo M, Alferez MJ, Lopez AI, Sanz SM, Campos MS., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/11949871). Iron is an integral component of hemoglobin in transporting oxygen from the lungs to all body cells, thus increasing the energy use for daily activities.

3. Calcium
In the investigation of micronutrients, calcium (Ca) and inorganic (i) phosphate (P) ,the two main constituents of hydroxyapatite and theirs effect on bone health found that they are endowed with a transport system that accumulates Pi inside the matrix vesicles, followed by the influx of Ca ions. This process leads to the formation of hydroxyapatite crystal and its subsequent association with the organic matrix collagen fibrils. In addition to this structural role, both Ca and Pi positively influence the activity of bone-forming and bone-resorbing cells. Pi plays a role in the maturation of osteocytes, the most abundant cells in bone. Osteocytes are implicated in bone mineralization and systemic Pi homeostasis, according to "Calciumand phosphate: a duet of ions playing for bone health" by Bonjour JP.(1)

4. Potassium
Potassium beside is important in maintaining the regular contraction and relaxation of the muscle, that helps to reducing the risk of hypokalemia, it also helps the lymphatic system in regulating the levels of fluid in the body, thus lessening the risk of lymphedema, swelling caused by the accumulation of lymph fluid. In a study of "Narrative review: evolving concepts in potassium homeostasis and hypokalemia" by Greenlee M, Wingo CS, McDonough AA, Youn JH, Kone BC., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/19414841), researchers found that recent experimental insights into the participation of feedback and feedforward control mechanisms in potassium homeostasis. New data make clear that feedforward homeostatic responses activate when decreased potassium intake is sensed, even when plasma potassiumconcentration is still within the normal range and before frank hypokalemiaensues, in addition to the classic feedback activation of renal potassiumconservation when plasma potassium concentration decreases.

5. Etc.

A.3. Other Health Benefits

1. Bone density
Since blackstrap molassaes contains high amount of calcium, it helps to build stronger, denser bones early in life and keeps bones strong and healthy later in life, thus reducing the risk of osteoporosis. Vitamin D is necessary for the absorption of calcium, according to the article of "Calcium supplements in people with osteoporosi" by John G F Cleland, Klaus Witte, Sue Steel, posted in BMJ (http://www.bmj.com/content/341/bmj.c3856.full), researchers wrote that Calcium supplements, given alone, improve bone mineral density,but they are ineffective in reducing the risk of fractures and might even increase risk.

3. Glucose and Fructose
Glucose and Fructose are simple sugar (monosaccharide) played an important role to enhance energy production in carbohydrate metabolism for brain cells need, through a chain chemical action of insulin produced by pancreas and potassium.

4. Magnesium
Beside helping to maintain the healthy bone through the proper ratio with calcium, according to the study of "Magnesium deficiency and osteoporosis: animal and human observations" by Rude RK, Gruber HE., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/15607643) magnesium also plays an essential role in relieving acute asthma by promoting the relaxation of bronchial muscles and normalizing breathing, according to the study of "Inhaled magnesium sulfate in the treatment of acute asthma" by Blitz M, Blitz S, Beasely R, Diner BM, Hughes R, Knopp JA, Rowe BH., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/16235345) researchers found that Nebulised inhaled magnesium sulfate in addition to beta2-agonist in the treatment of an acute asthma exacerbation, appears to have benefits with respect to improved pulmonary function in patients with severe asthmaand there is a trend towards benefit in hospital admission. Heterogeneity between trials included in this review precludes a more definitive conclusion.


B. Side effects
No serious side effects are unknown.




Back to Healthy Foods Index http://kylejnorton.blogspot.ca
Sources of Honey
(a) http://www.ncbi.nlm.nih.gov/pubmed/19103324
(b) http://www.ncbi.nlm.nih.gov/pubmed/15659187
(c) http://www.ncbi.nlm.nih.gov/pubmed/7765100
(1) http://www.ncbi.nlm.nih.gov/pubmed/22081690


Sources of Blackstrap Molasses
(a) http://www.ncbi.nlm.nih.gov/pubmed/20091616
(b) http://www.ncbi.nlm.nih.gov/pubmed/22050652
(c) http://www.ncbi.nlm.nih.gov/pubmed/21943200
(d) http://www.ncbi.nlm.nih.gov/pubmed/19754926
(e) http://www.ncbi.nlm.nih.gov/pubmed/21982267

How to Replace Salt to Get Rewards of Lower Blood Pressure and 14 Health Benefits, According to PubMed

By Kyle J. Norton
Too much salt intake has been proven to be a major cause of hypertension, leading to increase risk factor of heart disease and stroke.

Some researchers also found that too much salt intake are associated to higher probability of developing kidney diseases and stomach cancer as well as increasing risk of immune dysfunction.

According to statistic, from 2011 to 2012, the average daily sodium intake among U.S. adults was 3,592 mg far more than the max of 2300 mg recommended by FDA.

According to the joint study lead by Chonbuk National University, Korean low salt fermented soy sauce with yeasts  in production of high ethanol and 3-methyl-1-butanol for bacterial nilation is a balance of more complex and richer flavors with an identical flavor profile pattern to that obtained from high salt soy sauce(1).

Dr. Song YR, the lead scientist said, "using functional yeast cultures offers a technological option to manufacture salt-reduced soy sauce while preserving its typical sensory characteristics without affecting safety"(1)

Contrary to general belief, soy sauce was found to lower risk of hypertension through inhibiting activity of an angiotensin I-converting enzyme (ACE)(2) which is needed to constrict our blood vessels[1].

The information findings suggested that Korean low salt fermented soy sauce may be a good replacement of salt daily without affecting the taste of high salt intake individual as well as reducing risk of hypertension.

Here are health benefits of Korean low salt fermented soy sauce

A. Health benefits according to studies
[2]. Cardiovascular health
In the investigation of dietary proteins and their effect in heart diseases found that a direct cholesterol lowering effect of proteins has not been shown. Despite earlier research indicating that soy protein has cardioprotective effects as compared to other proteins, these observations have not been confirmed by randomized placebo-controlled trials. However, most experts recommend the consumption of foods rich in plant proteins as alternatives to meat and dairy products rich in saturated fat and containing cholesterol, according to "Dietary proteins and atherosclerosis" by Darioli R.(a)

[3]. Perennial allergic rhinitis (PAR)
In the study of isolated a halophilic lactic acid bacterium, Tetragenococcus halophilus Th221, from soy sauce moromi and the its effect on serum total immunoglobulin E, found that The change in serum total immunoglobulin E improved significantly at the end of the trial compared with the beginning in this group (p < 0.05). The safety of Th221 treatment was confirmed by laboratory tests and inspection of the general condition of each subject and concluded that Th221 can be expected to safely improve the symptoms of PAR, according to "Clinical efficacy of halophilic lactic acid bacterium Tetragenococcus halophilus Th221 from soy saucemoromi for perennial allergic rhinitis" by Nishimura I, Igarashi T, Enomoto T, Dake Y, Okuno Y, Obata A.(b)

[4]. Anti-allergic activities
In the assessment of oral supplementation of Shoyu polysaccharides (SPS) and its effective intervention for patients with perennial allergic rhinitis found that evaluation of the medication's effectiveness after 4 weeks treatment showed significant differences between the SPS- and placebo-treated groups (p<0.05). In conclusion, SPS of soy sauceimproved the quality of life for patients with perennial allergic rhinitis, and soy sauce would be useful in an anti-allergic therapy utilizing everyday foods, according to "Quality of life improvement with soy sauceingredients, Shoyu polysaccharides, in perennial allergic rhinitis: a double-blind placebo-controlled clinical study" by Kobayashi M, Matsushita H, Shioya I, Nagai M, Tsukiyama R, Saito M, Sugita T, Sugimura T, Yamamoto K.(c)

[5]. Breast cancer
In the analyzing of Shoyu and on the gastric mucosa of the rat found that the animals given shoyu were smaller than the controls; 15 intact rats receiving the sauce were healthy at 33 months compared with 7 controls. Only 9 of 50 operated rats lived 33 months. Breast tumors developed in 10 control rats but in none given shoyu. The distribution of other tumors was the same,... and concluded that Shoyu did not appear to be a carcinogen in the rat; its prolonged use impaired neither health nor longevity. Long-term use was associated with gastric mucus loss and nuclear changes in a few rats, occasionally with a mild gastritis. according to "Long-term effect of shoyu (Japanese soy sauce) on the gastric mucosa of the rat" by MacDonald WC, Dueck JW.(4)

[6]. Hypolipidemic effect
In the observation of Soy sauce (Shoyu), a traditional Japanese fermented seasoning and its effect on cholesterol level found that in a 4-week randomized, double-blind, placebo-controlled parallel group study, hyperlipidemic men (TG >150 mg/dl) were treated with 600 mg of SPS (n=15) or placebo (n=15) daily. After 4 weeks, serum TG levels in the SPS-treated group were significantly (P<0.05) lower than the baseline (0 week). In conclusion, SPS of soy sauce reduce lipid absorption, and soy sauce is a potentially promising seasoning for the treatment of hyperlipidemia through food, according to "Hypolipidemic effect of Shoyu polysaccharides from soy sauce in animals and humans" by Kobayashi M, Magishi N, Matsushita H, Hashimoto T, Fujimoto M, Suzuki M, Tsuji K, Saito M, Inoue E, Yoshikawa Y, Matsuura T.(e)


B. Health benefits according to concentration
[7]. Tryptophan
Tryptophan is one of the 10 essential amino acids which the body uses to synthesize the proteins for brain cells need, thus enhancing the nerve cells in information transmitting between themselves and cells in the parts of the body that reduces the risk of anxiety and depression, according to the study of "The effects of tryptophan depletion on neural responses to emotional words in remitted depression" by Roiser JP, Levy J, Fromm SJ, Nugent AC, Talagala SL, Hasler G, Henn FA, Sahakian BJ, Drevets WC.(1)

[8]. Manganese
Manganese beside plays an vital role for the proper and normal growth of human bone structure (accodring to the study of "Bone formation within alumina tubes: effect of calcium, manganese, and chromium dopants" by Pabbruwe MB, Standard OC, Sorrell CC, Howlett CR., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/15109850)), it also helps to reduce the risk of cancer, (according to the study of "The effects of 3, 4 or 5 amino salicylic acids on manganese-induced neuronaldeath: ER stress and mitochondrial complexes" by Yoon H, Lee GH, Kim DS, Kim KW, Kim HR, Chae HJ., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/21477646 researchers indicated that the salicylate analogues and the antioxidants did not mediate ER stress in this model. The salicylate analogues reduced reactive oxygen species (ROS) and reversed the deficient mitochondrial membrane potential that was induced by Mn. Taken together, the 3, 4, 5 ASA worked in a similar way, regulating the Mn-induced mitochondrial dysfunction and protecting cells.

[9]. Protein
Protein beside is important building block of bones, muscles, cartilage, skin, and blood, it also enhances the nervous system in information transmitting between cells and cells of the other parts of the body, thus reducing the risk of nervous tension, (according to the study of "The planar polarity protein Scribble1 is essential for neuronal plasticity and brain function" by Moreau MM, Piguel N, Papouin T, Koehl M, Durand CM, Rubio ME, Loll F, Richard EM, Mazzocco C, Racca C, Oliet SH, Abrous DN, Montcouquiol M, Sans N, posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/20660256)


[10]. Niacin or vitamin B3
Niacin or vitamin B3 beside is important in production of energy in metabolism of carbohydrate, it also essential for DNA repairing, according to the study of `Niacin deficiency delays DNA excision repair and increases spontaneous and nitrosourea-induced chromosomal instability in rat bone marrow`by Kostecki LM, Thomas M, Linford G, Lizotte M, Toxopeus L, Bartleman AP, Kirkland JB., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/17618655), production of steroid hormones in the adrenal gland, improving blood circulation and lowering the bad cholesterol (LDL) levels., according to the study of `Lowering LDLcholesterol with margarine containing plant stanol/sterol esters: is it still relevant in 2011?`by Doggrell SA., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/21296266)


C. Other health benefits
[11]. Cholesterol
Certain studies found that certain types of soy sauce (popular in Chinese cookery) have been shown to reduce the levels of bad cholesterol (LDL) because of the existence of large amounts of the isoflavones, so choose your soy sauce wisely, according to the study of `Soy isoflavones lower serum total and LDL cholesterol in humans: a meta-analysis of 11 randomized controlled trials`by Taku K, Umegaki K, Sato Y, Taki Y, Endoh K, Watanabe S., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/17413118)

[12]. Isoflavones
Isoflavones is one of the weak estrogen that can compete with estrogen for the same receptor sites, as it decreasing the health risks of excess estrogen, promoting healthy menstrual cycle and reducing the risk of cancers caused by high levels of strong estrogen., according to the study of `Red clover and soy isoflavones-an in vitro safety assessment`by Reiter E, Gerster P, Jungbauer A., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/21801124), researchers wrote that
Isoflavones and plant extracts significantly reduced the proliferation activity of the treated cancer cell lines.

[13]. Riboflavin
Riboflavin or vitamin B2 besides is important for the production of energy in the metabolism of fats, carbohydrates, and proteins due to its coenzymes, flavin adenine dinucleotide and Flavin mononucleotide properties, it also is the best of natural element for treating migraines and muscle pain reliever used together with magnesium, according to the study of `Effectiveness of high-dose riboflavin in migraine prophylaxis. A randomized controlled trial`by Schoenen J, Jacquy J, Lenaerts M., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/9484373)

[14]. Magnesium
Magnesium beside helps to maintain the right ratio with calcium, thus aiding the digestive system in absorption of calcium, according to the study of `Associations of calcium and magnesium in serum and hair with bone mineral density in premenopausal women`by Song CH, Barrett-Connor E, Chung JH, Kim SH, Kim KS., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/17848724) it also reduces the risk of irregular heart beat and impairs glucose tolerance, according to the study of `Dietary magnesium deficiency induces heart rhythm changes, impairs glucose tolerance, and decreases serum cholesterol in post menopausal women`by Nielsen FH, Milne DB, Klevay LM, Gallagher S, Johnson L., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/17536123)

Sources
(1) Effects of indigenous yeasts on physicochemical and microbial properties of Korean soy sauce prepared by low-salt fermentation by Song YR1, Jeong DY2, Baik SH3.(PubMed)
(2) Purification and identification of an angiotensin I-converting enzyme inhibitor from soy sauce.
Kinoshita E1, Yamakoshi J, Kikuchi M(PubMed)

(a) http://www.ncbi.nlm.nih.gov/pubmed/22139566
(b) http://www.ncbi.nlm.nih.gov/pubmed/19240374
(c) http://www.ncbi.nlm.nih.gov/pubmed/15492861
(d) http://www.ncbi.nlm.nih.gov/pubmed?term=Shoyu%20and%20breast%20cancer
(e) http://www.ncbi.nlm.nih.gov/pubmed/18813866
(1) http://www.ncbi.nlm.nih.gov/pubmed/19539268