Holistic Health Articles and Research Related to Herbal Medicines, Foods and Phytochemicals

Friday, 2 March 2018

Herbal Therapy: The Best of Perennially Herbal Fennel In Ameliorated Risk, Progression and Treatment of Prostate cancer

Kyle J. Norton

Fennel may have potential and positive effect in reduced risk, progression and treatment of prostate cancer, some scientist suggested.

Prostate caner is a chronic condition characterized by abnormal growth of prostate tissue. At he later stage, the cancerous cells may travel a distance away to infect other healthy cells and tissues.

Fennel (Foeniculum vulgare) is a plant species of genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean, used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...

Nutrients
1. Carbohydrates
2. Fiber
3. Protein
4. Thiamine (Vitamin B1)
5. Riboflavin (Vitamin B2)
6. Niacin (Vitamin B3)
7. Pantothenic acid (B5)
8. Vitamin B6
9. Folate (Vitamin B9)
10. Vitamin C
11. Calcium
12. Copper
13. Iron
14. Magnesium
15. Molybdenum
16. Phosphorus
17. Potassium
18. Zinc

In the study to investigate the effect of 5 herbal medicine in different quantity in some different formulas represented by FB, FM, PP, HF and FBL101 in risk of prostate cancer, including licorice, black cohosh, Dong Quai, false unicorn and vitex berry root extracts, fennel seed extract, researchers at the National Institute of Health found that FB, FM, PP, HF and FBL101 inhibited PC3 tumor growth by 53%, 75%, 80%, 81% and 87%, respectively.

In an androgen-independent human prostate cancer cell line CWR22R, all 5 formulas also inhibited the caner cell proliferation without alternating levels of testosterone.

However, administration of formula PP and FBL101 showed a significantly reduced VEGF levels with function in stimulated formation of new blood vessels in initiated proliferation in PC3 and CWR22R tumors.

Further more, intratumoral microvessel density measurement in expression of tumor growth with aggressive tumor behavior, was decreased in PC3 tumors treated with all five supplements but only in CWR22R tumors treated with HF.

Dr. Ng SS, after taking into account of other cofounders said, "herbal supplements containing the aforementioned extracts inhibit the growth of prostate tumor xenografts, possibly in part by antiangiogenic mechanisms".

These results demonstrated that fennel extract and other herbal components may be considered as preventive and therapeutic agents for treatment of prostate cancer without indicating the efficacy of individual herb.

The above differentiation were supported by the study of the Alexandria University in evaluation of anethole, a major constituent of Foeniculum vulgare (fennel) essential oil, a widely used folk medicine for treatment of prostate cancer.

According to the experiment, application of the bioactive compound anethole exerted a strong activity against proliferation, clonal growth and migration of PC-3 cells, through generation of ROS in induction of cytotoxicity through damage the DNA of the cancer cells.

Additional analysis of the efficacy, the application also stimulated the penetration of essential oil anethole in permeabilization of the mitochondrial and lysosomal membranes of PC3 cancer cell in induction of cancer cells death, executed by caspase-3 and -9 pathways and PARP cleavage in induction of apoptosis.

Interestingly, injection of anethole isolated from fennel essential oil also induced elevation of Bax/Bcl-2 protein ratio, in initiated the onset of prostate cancer cell death through cell cycle arrest.

Further observation of anethole action, researchers found that anethole inhibited prostate cancer cells through cell cycle arrest in G2/M phase ameliorated by levels of cyclins D1, CDK-4 and c-Myc proteins in promoted cancer cell cycle progression and enhanced production of levels p21 and p27 in exhibited tumor suppressible activity.

Finally, anethole also suppressed NF-κB protein in activated production of TNF-α in induction of anti-apoptosis in prostate cancer cells.

Taken together, the finding evidences strongly suggested that long term intake of fennel and its bioactive anethole may have substantial implication in prevention and treatment of prostate cancer. But intake of fennel supplement should be taken with care to prevent acute liver toxicity.

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA FOR WOMEN

Arthritis Is Curable

You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Anethole Inhibits The Proliferation Of Human Prostate Cancer Cells Via Induction Of Cell Cycle Arrest And Apoptosis by Elkady A(PubMed).
(2) Antitumor activity of herbal supplements in human prostate cancer xenografts implanted in immunodeficient mice by Ng SS1, Figg WD.(PubMed)

Thursday, 1 March 2018

The Magic of Camellia Sinensis Leaves: Green Tea in Expression of Anti Influenza Activity

Kyle J. Norton

Green tea, the Camellia sinensis leaves may have a therapeutic and positive effect in reduced infectious risk by influenza, some scientists suggested.

Influenza, is also known s "the flu", is an infectious disease caused by an influenza virus
Green tea, is a precious drink processed numbers of health benefit and known to almost everyone in Asia and Western world.

In the investigated the green tea effect in reduced risk of influenza viral overspreading in general population, researchers at the Yonsei University conducted a study to evaluate catechin derivatives with different alkyl chain length and aromatic ring substitutions at the 3-hydroxyl group synthesized from epigallocatechin (EGC) and (+)-catechin (C) activity against influenza virus.

According to the experiment, application of catechin derivatives, carrying moderate chain length (7-9 carbons) exerted a pronounced effect in inhibited over expression of the virus in compared to those with aromatic rings.

Interestingly, injection of the 5'-hydroxyl group did not significantly contribute to antiviral activity against trihydroxy benzyl moiety.

However, administration of both derivatives demonstrated an inhibitory effect for all six influenza subtypes tested including three major types of currently circulating human influenza viruses (A/H1N1, A/H3N2 and B type), H2N2 and H9N2 avian influenza virus, through strongly inhibited adsorption of the viruses on red blood cell (RBC).

In vivo, the drivatives also expressed an impressive activity in restricted the growth of avian influenza virus with minimum inhibition concentration (MIC) of 5-10 microM far exceeding the dose of conventional medicine oseltamivir or M2 proton channel inhibitor amantadine with the same purposes.

Further analysis suggested that the derivatives isolated from actechin inhibited effect were attributed to the mediation and interaction with hemagglutinin (HA)/viral membrane at the initial stage of infection.

Dr. Song JM, the lead author, after taking account of all assessment said, "The broad spectrum activity against various subtypes of influenza viruses may complement the limitations of current antivirals and contribute for managing potentially emerging influenza pandemic".

Importantly, in the comparison of the theaflavins fraction (TF80%, with a purity of 80%) and three theaflavin (TF) derivatives potent inhibitory effects against influenza virus in vitro, scientists at the Chinese Academy of Medical Sciences & Peking Union Medical College indicated that application displayed a significant inhibitory effects on the HA of three different subtypes of influenza virus strains [A/PR/8/34(H1N1), A/Sydney/5/97(H3N2) and B/Jiangsu/10/2003] with 50% inhibitory concentration (IC(50)) values ranging from 9.27 to 36.55 μg/mL, probably though expression and interaction on HA as above differentiation.

Additionally, TF derivatives inhibited the over expression of viral particle infectivity consistently and corelatively with the inhibitory effect on HA.

According to the qPCR and nuclear localization of the influenza virus vRNP assays, all applications exerted anti infectivity by interrupting the viral replication and also decreased the production of inflammatory cytokine IL-6 in induction of serious tissue injury and apoptosis.

The above evaluation were supported by the Yonsei University study of the polyphenolic compound catechins ((-)-epigallocatechin gallate (EGCG), (-)-epicatechin gallate (ECG) and (-)-epigallocatechin (EGC)) from green tea in inhibited influenza virus replication in cell culture and for potentially direct virucidal effect.

According to the results, among all compound selected in the assessment, EGCG and ECG were found to be potent inhibitors of influenza virus replication in MDCK( in a suitable transfection host for influenza research) cell culture, including A/H1N1, A/H3N2 and B virus, observed in all influenza virus subtypes tested. with 50% effective inhibition concentration (EC50) of EGCG, ECG, and EGC for influenza A virus at doses of 22-28, 22-40 and 309-318 microM.

The effective compounds EGCG and ECG also displayed an exhibited hemagglutination inhibition activity, similar to those in above studies.

Moreover, in compared to the EGCG and ECG anti influenza virus efficacy, researchers surprisingly found that at high concentration, EGCG + ECG also suppressed viral RNA synthesis in MDCK cells whereas EGC failed to show similar effect and EGCG + ECG inhibited the neuraminidase activity more effectively than the ECG.

These results reaffirmed the expression of green tea biocative polyphenols antiviral effect of catechins on influenza virus is mediated not only by specific interaction with HA, but also alter the physical properties of viral membrane, Dr. Song JM, the lead author of the study suggested.

Taken together, green tea with abundant phytochemical polyphenols may be considered as a functional food for reduced risk, progression and treatment of infleunza infection.

Reprint of this article is welcome with author name and link to the article sources intact https://kylejnorton.blogspot.ca/2018/03/the-magic-of-camellia-sinensis-leaves.html

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA For Women

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Sources
(1) Biological evaluation of anti-influenza viral activity of semi-synthetic catechin derivatives by Song JM1, Park KD, Lee KH, Byun YH, Park JH, Kim SH, Kim JH, Seong BL.(PubMed)
(2) In vitro anti-influenza virus and anti-inflammatory activities of theaflavin derivatives by Zu M1, Yang F, Zhou W, Liu A, Du G, Zheng L.(PubMed)
(3) Antiviral effect of catechins in green tea on influenza virus by Song JM1, Lee KH, Seong BL.(PubMed)

Herbal Therapy: Green Tea and Its Bioactive Epigallocatechin gallate (EGCG) in Ameliorated Risk, Progression and Treatment of Amyotrophic Lateral Fclerosis (Lou Gehrig's disease)

Kyle J. Norton

Green tea may have a therapeutic and positive effect in reduced risk, progression and treatment of amyotrophic lateral sclerosis (ALS), some scientists suggested.

Green tea is a precious drink processed numbers of health benefit and known to almost everyone in Asia and Western world.

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a specific disease involved the death of neurons in controlling voluntary muscles.

According to the research published by the Hanyang University, administration of green tea Epigallocatechin gallate (EGCG) exerted a neuroprotective effect in reduced oxidative stress in orchestrated death of neurons.

In the evaluation of green tea EGCG in risk of amyotrophic lateral sclerosis (ALS) in human G93A(with function in responsible for destroying free superoxide radicals in the body) mutated Cu/Zn-superoxide dismutase (SOD1) gene in mice model, scientists found that

application of green tea EGCG at doses of 1.5, 2.9, and 5.8 microg/g body weight, dissolved in 0.5 ml of 0.9% sterile NaCl intraorally every day after 60 days of age demonstrate significant effects in prolonged the symptom onset and life span of ALS mice through preserved more survival and attenuated death signals.

The result of increased life span of mutated gene mice was attributed to increased antioxidant activity of green tea in inhibited the levels of ROS in reduced cytotoxicity in initiated death of neurons in controlling voluntary muscles.

Further analysis of the effect of green tea in mutated SOD1-G93A in transgenic mice and wild-type mice randomly divided into EGCG-treated groups (10 mg/kg, p.o) and vehicle-treated control groups to assess the motor function, starting at the age of 70 days researchers found that injection of green tea treatment mice display a strong effect in delayed the onset of disease, and extended life span, similar to those in the Hanyang study.

Additional differentiation also indicated that green tea treatment group stimulated the production of numbers of new motor neurons in compared to control mice,

Interestingly, the application also decreased the over expression of microglial activation in initiated the inflammatory response due to neuronal damage and removed the damaged cells caused by phagocytosis production.

Prolonged and over expression of inflammatory cytokines may increase risk of neuron damage and in some cases death of the nerve cells.

Researchers in depth analysis showed that green tea reduced immunohistochemical reaction of NF-kappaB in response to the neuron damage (by antigens) through stimulated production of pro inflammatory factors (as antibody) and cleaved caspase-3 in induction of neuron apoptosis.

Moreover, application of green EGCG also expressed a similar result as in other studies in decreased protein level of iNOS and NF-kappaB in the spinal cords in orchestrated free radical NO levels and inflammatory cytokines in neuron cell death in the spinal cord involving the onset of ALS.

Dr. Xu Z, the lead author after taking into account of other co founders said, "this study provides further evidences that EGCG has multifunctional therapeutic effects in the mouse model of ALS".

These result were supported by the study of the green tea effect in risk of Lou Gehrig's disease through reviewing the food selection of 44-item food frequency questionnaire of 1 million men and women enrolled and conducted in 1989 through 2002 for ALS mortality.

According to results of the study, researchers at the Harvard School of Public Health suggested that green tea injection is associated to reduced mortality rate of patients.

The information findings suggested that green tea and its bioactive polyphenol Epigallocatechin gallate (EGCG) may be considered as a function food for reduced risk and used combination with standard medicine in delayed progression and treatment of Amyotrophic lateral sclerosis (ALS).

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA For Women

Sources
(1) Diet and amyotrophic lateral sclerosis by Morozova N1, Weisskopf MG, McCullough ML, Munger KL, Calle EE, Thun MJ, Ascherio A.(PubMed)
(2) Neuroprotective effects of (-)-epigallocatechin-3-gallate in a transgenic mouse model of amyotrophic lateral sclerosis by Xu Z1, Chen S, Li X, Luo G, Li L, Le W.(PubMed)
(3) The effect of epigallocatechin gallate on suppressing disease progression of ALS model mice by Koh SH1, Lee SM, Kim HY, Lee KY, Lee YJ, Kim HT, Kim J, Kim MH, Hwang MS, Song C, Yang KW, Lee KW, Kim SH, Kim OH.(PubMed)

Wednesday, 28 February 2018

Herbal Therapy: Fennel, A Potent Functional Food for Treatment of Infantile Colic

Kyle J. Norton

Fennel may have a profound and positive effect in reduced risk of infantile colic, some scientists suggest.

Infantile colic is a reaction of the infant if episodes of crying for more than three hours a day, for more than three days a week, for three weeks in an otherwise healthy child. The condition has strong impacted in psychological, emotional, and physical burden to parents.

Fennel (Foeniculum vulgare) is a plant species of genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean, used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...

Nutrients
1. Carbohydrates
2. Fiber
3. Protein
4. Thiamine (Vitamin B1)
5. Riboflavin (Vitamin B2)
6. Niacin (Vitamin B3)
7. Pantothenic acid (B5)

In a randomized, double-blind, placebo-controlled trial to investigate the effectiveness and side effects of phytotherapeutic agent with Matricariae recutita, Foeniculum vulgare and Melissa officinalis in treatment of infantile colic in a total of the 93 breastfed colicky infants conducted by the John Wiley & Sons, Ltd, after a 3 day observation period, the infants randomly assigned to groups treated with phytotherapeutic agent (PA) and group received placebo twice a day for 1 week, researchers found that crying time in group received PA was reduced substantially in 85.4% of subjects in compared to 48.9% subjects in placebo group against baseline.

PA treatment group exerted no side effect during the period of experiment.

Base on the result, researchers suggested that PA demonstrated a significant activity within one weeks of application in infantile colic.

Furthermore, the St. Petersburg Medical Academy of Postdoctoral Education in the concerns of the side effects of 5% of infants treated with dicyclomine hydrochloride, the only pharmacological treatment for infantile colic, with substantial side effects, including death, conducted a randomized placebo-controlled trial of 125 infants, 2 to 12 weeks of age from 2 large multi-specialty clinics by assigned them to either group treated with fennel or placebo, indicated that fennel treatment group improves the crying time episodes and frequency sidnificantly in compared to the placebo group.

According to the Wessel assay, infantile colic was reduced by 65% (40/62) in the treatment group in compared to only 23.7% (14/59) in placebo.

Further analysis also found that application of fennel induced a risk reduction of 41% in compared to placebo without causing any side effects.

Although the causes of infantile colic is unknown, some researchers suggested that the results of fennel in treatment of infantile colic may be attributed to its efficacy in the hypothetical conditions catalyzed by

*Abnormal gastro-intestinal function caused by imbalanced of bacterial ratio

According to the literature reported by the Swansea University, application of fennel essential oil have a sustainable effect in inhibited E. coli growth, observed by disc diffusion assays and in liquid culture.

These results were illustrated by the effect of an aqueous extract of the aerial part and aqueous extract of seed sample of fennel.

Fennel inhibited overgrowth of Agrobacterium radiobacter pv. tumefaciens, Erwinia carotovora, Pseudomonas fluorescens, andPseudomonas glycinea, Enterococcus faecalis, Staphylococcus aureus, Escherichia coli, Klebsiella pneumonia, Pseudomona aeruginosa, Salmonella typhi, Salmonella typhimurium, Shigella flexneri, and Bacillus cereus in maintenance integrity of digestive function.

Further differentiation also suggested that fennel has a strong impact in protected the gastric damage through significantly increased nitrite, nitrate, ascorbic acid, retinol, and beta-carotene levels.

Dr. Shamkant B. Badgujar, the lead author, in the differentiation of fennel, in regard to the gastrointestinal effect, said, "Foeniculum vulgare is indicated in the treatment of spastic gastrointestinal disturbances, in some forms of chronic colitis (which resist other treatments), in dyspepsias from gastrointestinal atony, in dyspepsias with the sensation of heaviness in the stomach, and so forth.The addition of fennel to preparations containing anthraquinonic components reduces the occurrence of abdominal pain often associated with this type of laxative"

* In Psychological aspect of mother such as mother’s depression, anxiety and dis-tress during pregnancy in induction of infantile colic, although there are no direct literature to confirm the efficacy of fennel in treating syndromes of these group of women, but in the study of psychological symptoms in women with premenstrual syndrome, application of fennel seed was associated in deceased depression and anxiety.

Also, in stress induced maternal anxiety and depression, application of fennel extract (50, 100 and 200 mg/kg body weight) showed a significant improvement of urinary levels of vanillyl mandelic acid(VMA) and ascorbic acid excretion levels in measurement of potentially psychological stress in fennel treatment group in compared to the normal group.

These results indicated that the extract of entire plant of F. vulgare pay have a potential effect by acting as an anti-stress agent in reduced depression and anxiety in maternity.

* In food allergic aspect, although there are no direct study in expression of fennel improved immune response against food allergy,.

Some researchers postulated that anethole, a bioactive compound from fennel inhibited food allergy probably through enhacing immune system food hypersensitivity response by modulating the expression of Foxp3+ in regulated the development and function T cells and inhibition of Th2 cytokines in promoted antibodies production of immunoglobulin E (IgE), thus reducing immune system overreacts to an allergen.

Taken together, the findings suggested that fennel may be considered as a function food for treatment of infantile colic, however, a large sample size and study by multi centers are necessary to reconfirm the viability.

Reprint of this article is welcome with name of the author and link back to sources intact https://kylejnorton.blogspot.ca/2018/02/herbal-therapy-fennel-potent-functional.html

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA FOR WOMEN

Arthritis Is Curable

Sources
(1) A randomized double-blind placebo-controlled trial of a standardized extract of Matricariae recutita, Foeniculum vulgare and Melissa officinalis (ColiMil) in the treatment of breastfed colicky infants by Savino F1, Cresi F, Castagno E, Silvestro L, Oggero R.(PubMed)
(2) The effect of fennel (Foeniculum Vulgare) seed oil emulsion in infantile colic: a randomized, placebo-controlled study by Alexandrovich I1, Rakovitskaya O, Kolmo E, Sidorova T, Shushunov S.(PubMed)
(3) Illicium verum Extract and Trans-Anethole Attenuate Ovalbumin-Induced Airway Inflammation via Enhancement of Foxp3+ Regulatory T Cells and Inhibition of Th2 Cytokines in Mice by Yoon-Young Sung,1 Seung-Hyung Kim,2 Dong-Seon Kim,3 Ji-eun Lee,2 and Ho Kyoung Kim1(Hidawi)
(4) Comparison of the antibacterial activity of essential oils and extracts of medicinal and culinary herbs to investigate potential new treatments for irritable bowel syndrome by Thompson A1, Meah D, Ahmed N, Conniff-Jenkins R, Chileshe E, Phillips CO, Claypole TC, Forman DW, Row PE.(PubMed)
(5) Comparing the Effects of Echinophora-platyloba, Fennel and Placebo on Pre-menstrual Syndrome by Masoumeh Delaram,1,* Soleiman Kheiri,2 and Mohammad Reza Hodjati(PMC)

Herbal Therapy: Herbal Arnica in Ameliorated Pain and Muscle Tenderness After Intensive Exercise?

Herbal Arnica may have a therapeutic and enhanced physical performance through reduced pain associated to overworked muscles, some scientists suggested.

Arnica is a herbaceous species, genus perennial, belongings to the family Asteraceae, antive to Europe and Asia, used in herbal medicine for centuries to treat strains, sprains, and bruises.
Wound healing is process of repairing after damage of skin, tissues, organs, etc.

The ingredients
Helenalin, chamissonolid, Sesquiterpene lactone, lignans of the furofuran, dibenzylbutyrolactone, dibenzylbutyrolactol types, pinoresinol, epipinoresinol, phillygenin, matairesinol, nortrachelogenin, and nortracheloside, six dibenzylbutyrolactol derivative.

Arnica used in herbal medicine in reduced bruises, sprains, soreness, and swelling and for relief of arthritis, muscle, and joint pain.

According to some articles in herbal medicine, application of herbal Arnica showed a significant effect in improved muscle pain and stiffness through its soothing, moisturizing comfort and relief from these symptoms activity.

In a double-blind, placebo-controlled trial of 53 subjects conducted by the Memorial Family Medicine Residency Program, researchers suggested that the opposite results were found after each participant received 2 tubes of cream, 1 with active Arnica and 1 with placebo.

According to the study, application of creams applied to the lower legs immediately after the exercise, and again at 24 and 48 hours postexercise according to the "RIGHT" or "LEFT" labels, application arnica strong increaseed Pain scores in compared to placebo, 24 hours after exercise but the injection pronounced no difference in day 3 and day 4 again in compared to placebo.

The results indicated that topical Arnica exerted a significant higher in pain score instead of relieved pain as expected by the study.

Dr. Adkison JD, the lead author, after taking into account of other confounder said, "Rather than decreasing leg pain, arnica was found to increase leg pain 24 hours after eccentric calf exercises. This effect did not extend to the 48-hour measurement".

The above differentiation were supported by the investigation of the homeopathic Arnica 30X can reduce muscle soreness following long-distance running more than a placebo conducted by the Research Council for Complementary Medicine.

According to Dr. Vickers AJ, the lead scientist, in the total of 519 runners anticipating delayed-onset muscles soreness after long-distance races in the observation of subjects by visual analog scale and Likert scale of muscle soreness every morning and evening for the 5 days following their race, application of homeopathic medicine (Arnica 30x) showed no different of pain scores in compared to placebo.

As the Mean of 2-day visual analog soreness scores for Arnica and placebo were 45.2 mm and 41.0 mm, respectively.

And the 95% confidence interval of the population mean was between 8.81 mm in favor of placebo and 0.51 mm in favor of Arnica.

However, in the investigation to determine the effect of topical Arnica in reducing pain, indicators of inflammation and muscle damage, and in turn improved performance in well-trained males experiencing delayed onset muscle soreness (DOMS) in 20 well-trained males matched by maximal oxygen uptake (V̇O2 Max) completed a double-blind, randomized placebo-controlled trial, researchers found that topical Arnica reapplied every 4 waking hours showed a moderate in reduced pain and improved muscle tenderness three days post-eccentric exercise, but do not improved muscle damage and ameliorated inflammation through blood analysis.

Some researchers insisted that the conflict result of the studies may be attributed to the limitation of the small sample size, the geography, (including the climate and soil) of the herb was growth and when the herb was harvested,..... and suggested that a large sample size conduced by multi centers to viability the efficacy of herbal Arnica in either ways.

Reprint of this article is welcome with author name and link to the article sources intact https://kylejnorton.blogspot.ca/2018/02/herbal-therapy-does-hebral-arnica.html

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA FOR WOMEN

Arthritis Is Curable

You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) The effects of topical Arnica on performance, pain and muscle damage after intense eccentric exercise by Pumpa KL1, Fallon KE, Bensoussan A, Papalia S.(PubMed)
(2) The effect of topical arnica on muscle pain by Adkison JD1, Bauer DW, Chang T.(PubMed)
(3) Homeopathic Arnica 30x is ineffective for muscle soreness after long-distance running: a randomized, double-blind, placebo-controlled trial by Vickers AJ1, Fisher P, Smith C, Wyllie SE, Rees R.(PubMed)

Tuesday, 27 February 2018

Alternative Therapy: Yoga, as An Effectively Complementary Practice in Alleviated Symptoms of Migraine

By Kyle J. Norton

Yoga intervention may be helpful in reduced symptoms of migraine, particularly in women, epidemiological studies suggested

Migraine headache is one most common headache defined as a condition of chronic neurological disorder of moderate to severe headaches, and nausea, usually developed gradually over 5–20 minutes and last for less than 60 minutes.

Yoga, the ancient technique practice for harmonized external and internal body well beings, through breath control, meditation, bodily movement and gesture..... has been best known for people in Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

According to the study of migraine patients randomly given either conventional care (n = 30) or Yoga with conventional care (n = 30) and yoga practice session for 5 days a week for 6 weeks along with conventional care.
* Yoga group expressed a strong improvement in clinical variables in compared to control
* In yoga alone group, the improvement was found profoundly more effective in compared to both yoga + conventional care and conventional care groups.

Dr. the led authors said, "Headache frequency and intensity were reduced more in Yoga with conventional care than the conventional care group alone. Furthermore, Yoga therapy enhanced the vagal tone and decreased the sympathetic drive, hence improving the cardiac autonomic balance".

Truly, yoga slow breathing and meditation ameliorated stress cause of central nervous system in stimulated production of stress hormones in induction of hormone imbalance that trigger sensitive primary nerve in carried pain impulses from your mouth, teeth, head, face, ears, and neck and reduced production of nitric oxide synthases (iNOS) in facilitated muscle constriction in increased migraine pain, through decreased levels of nitric oxide (NO), a free radical in the regulation of cerebral and extra cerebral cranial blood flow.

The results suggested that yoga participated may also reduce risk of migraine caused by hormone interference medication such as hormonal contraceptives and hormone replacement treatment.

Furthermore, by calming the central nervous system yoga practice also reduced expression of stress hormones in orchestrated production prostaglandin hormone PE2 and decreased serotonin hormone, a type of neurotransmitter, in initiated muscle constriction and provoked migraine-like attacks.

Moreover, yoga mindfulness also reconnected and re balanced the mind and the body, by bring back the presence, while letting them go such as stress or dealing them in a profound and positive ways, thus reducing the implication of psychological syndrome, such as depression and anxiety in precipitated hormone imbalance and insulin fluctuation in facilitated migraine, during menstrual cycle and menopausal women.

The above differentiation were supported by the randomized controlled trial of patients with migraine without aura assigned to yoga therapy or self-care group for 3 months, conducted by the University of Rajasthan.

According to study, yoga intervention group expressed less complaints related to headache intensity, frequency, pain rating index, affective pain rating index, total pain rating index, anxiety and depression scores and less used of symptomatic medication in compared to the self-care group, after adjusting to the baseline.

Importantly, the study demonstrated a significant reduction of symptoms of migraine headache in all aspects and frequency and associated clinical features. Dr. John PJ, the led author opinionated.

And, the study of a total of 42 women patients with migraine enrolled and randomized into either a yoga exercise group placed in yoga training program in addition to the same medical treatment or a control group received only medication for 12 weeks, lead by the Isfahan University of Medical Sciences.

The final results suggested that yoga intervention exerted a significant effect on endothelial function of migraineurs, through decreased plasma level of vascular cell adhesion molecule (VCAM), but expressed no significant difference in plasma levels of intercellular adhesion molecule (ICAM), in compared to control group.

Levels of vascular cell adhesion molecule (VCAM) and intercellular adhesion molecule (ICAM) were elevated in patients with migraine headache.

Taking together, there is no doubt that yoga may be considered as a complementary treatment of symptoms of migraine.

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources

(1) Effect of Yoga on migraine: A comprehensive study using clinical profile and cardiac autonomic functions by Kisan R1, Sujan M2, Adoor M2, Rao R3, Nalini A4, Kutty BM2, Chindanda Murthy B5, Raju T2, Sathyaprabha T2.(PubMed)
(2) Effectiveness of yoga therapy in the treatment of migraine without aura: a randomized controlled trial by John PJ1, Sharma N, Sharma CM, Kankane A.(PubMed)
(3) Preventive Effects of a Three-month Yoga Intervention on Endothelial Function in Patients with Migraine by Naji-Esfahani H1, Zamani M2, Marandi SM2, Shaygannejad V3, Javanmard SH1.(PubMed)
(4) Prostaglandins and prostaglandin receptor antagonism in migraine by Antonova M1.(PubMed)
(5) Randomized, controlled trial of phytoestrogen in the prophylactic treatment of menstrual migraine by Burke BE1, Olson RD, Cusack BJ.(PubMed)
(6) The role of nitric oxide (NO) in migraine, tension-type headache and cluster headache by Olesen J1.(PubMed)

Herbal Therapy: Arnica, a Potent Anti Edema and Bruising Herbal Medicine

By Kyle J. Norton

Herbal Arnica may have a therapeutic and substantial effect in reduced progression and treatment of edema, some scientists suggested.

Arnica is a herbaceous species, genus perennial, belongings to the family Asteraceae, antive to Europe and Asia, used in herbal medicine for centuries in treatment of strains, sprains, and bruises.
Wound healing is process of repairing after damage of skin, tissues, organs, etc.

Edema is a condition, characterized by excessive accumulation of fluids in some tissues within the body.

The ingredients
Helenalin, chamissonolid, Sesquiterpene lactone, lignans of the furofuran, dibenzylbutyrolactone, dibenzylbutyrolactol types, pinoresinol, epipinoresinol, phillygenin, matairesinol, nortrachelogenin, and nortracheloside, six dibenzylbutyrolactol derivative.

In the study to compare the efficacy of herbal Arnica and corticosteroids in reduced postoperative edema and bruising associated with rhinoplasty of 48 primary rhinoplasty patients randomized assigned to three groups as follow

* Group P received 10 mg of dexamethasone (intravenously) intraoperatively followed by a 6-day oral tapering dose of methyl-prednisone
* Group A received Arnica three times a day for 4 days, and
* Group C received neither agent and served as the control.

With 3 blinded panelists rated the extent of ecchymosis, the intensity of the ecchymosis, and the severity of the edema

After observating the study over the entire period, scientists postulated that

* There were no significant differences in all groups on the day 2 of postoperative

* In compared to increased swelling of control group, both group A and P demonstrated a significant improvement in edema rating.

Interestingly, conventional medicine administration group exerted higher intensity of ecchymosis compared to groups A and C on the day of postoperative and all groups displayed no difference of magnitude of edema.

However, between period of day 2 and 8, groups A and C exhibited significantly more resolution of ecchymosis in compared to group P.

The results suggested that although herbal Arnica may have a therapeutic property in reducing edema during the early postoperative period, the herbal medicine did not provide similar benefits in regard to extent and intensity of ecchymosis in compared to corticosteroids.

In order to further confirmation of the effect of herbal Arnica in reduced postoperative ecchymosis and edema, researchers at the joint study lead University of Miami Miller School of Medicine, conducted an investigation in a select population of healthy volunteers after oculofacial surgery by examining the postoperative course and medical records of a total of 27 patients (16 females, 11 males) with age range was 18 to 70 years using topical Arnica and Ledum after undergoing common oculofacial procedures, including blepharoplasty, browpexy, and rhinoplasty, in the hands of 4 surgeons at tertiary referral centers from July 1, 2012 to December 31, 2012.

According to the result of experiment, application of Arnica 50 M (10) 50% and Ledum 50 M (10) pads bilaterally after surgery through postoperative day 6, showed a significantly accelerated healing from day 7 to day 12 in dose depending manner, without inflicting any adverse effects.

The findings suggested that application of composited Arnica and Ledum displays a potential efficacy in reducing postoperative ecchymosis and edema after oculofacial surgery.

The above differentiation of herbal Arnica in improved edema after surgery were supported by the joint study lead by the Research Center of University of adult male Wistar rats inoculated with 1% carrageenan into the footpad to induce emeda then treated with Arnica montana 6cH, dexamethasone (4.0 mg/kg; positive control) or 5% hydroalcoholic solution (negative control), per os, each 15 minutes, between 30 and 180 minutes after the irritant inoculation.

According to the investigation, application of Arnica group exhibited anti edema through increased lymphatic edema absorption, particularly, in late edema presented less intense edema treatment group after adjusting to the individually qualitative of inflammatory vascular events.

Moreover, the edema inhibition of Arnica was attributed to significant reduced mast cell degranulation and increased lymphatic vessels diameter and decreased production of prostaglandins associated to the development of edema, caused by subcutaneous carrageenan injection in induction of local inflammation.

Taken together, herbal Arnica may be considered as a functional food in reduced progression and for treatment of edema and ecchymosis.

Reprint of this article is welcome with author name and link to the article intact https://kylejnorton.blogspot.ca/2018/02/herbal-therapy-green-tea-and-its_24.html

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) A randomized, controlled comparison between arnica and steroids in the management of postrhinoplasty ecchymosis and edema by Totonchi A1, Guyuron B.(PubMed)
(2) Assessing the Effectiveness of Arnica montana and Rhododendron tomentosum (Ledum palustre) in the Reduction of Ecchymosis and Edema After Oculofacial Surgery: Preliminary Results by Kang JY1, Tran KD, Seiff SR, Mack WP, Lee WW.(PubMed)
(3) Inflammatory Process Modulation by Homeopathic Arnica montana 6CH: The Role of Individual Variation Ana Paula Kawakami,1 Cesar Sato,1 Thayna Neves Cardoso,1 and Leoni Villano Bonamin(Hidawi)