Holistic Health Articles and Research Related to Herbal Medicines, Foods and Phytochemicals

Wednesday, 4 October 2017

Herbal Therapy: Green Tea in Reduced Risk of Hyperglycemia and Early Onset of Type 2 Diabetes

By Kyle J. Norton

The use of plants for healing purposes has been predated long before the existence of modern medicine. Herbal plants have formed a fundamental source for conventional medicine in discovery of single ingredient medication, including aspirin (from willow bark), quinine (from cinchona bark), and morphine (from the opium poppy)......

Green with a ton of phytochemicals has been found to process variuos health benefits reported by large numbers of research and study. However, long term injection of large amounts may obstruct the balance of yin-yang, inducing "yin excessive syndrome" or "yang vacuity syndrome"according to traditional Chinese medicine's Yin-Yang theory. It is recommended to add a slice of ginger in your drink for a purpose of neutralization.

Recently study by renowned institute postulated that regular green tea intake may be associated to reduced risk of developed hyperglycemia in healthy individual and prevented early onset of diabetes in people with hyperglycemia.

According to the Third Military Medical University, regular consumption of green tea or green tea extract improved insulin sensitivity and glycaemic control in populations with diabetics.

In the review of literature found in data base of PUBMED, The Cochrane Library, EMBASE, ISI Web of Knowledge, Chinese Biomedical Literature Database and Chinese Scientific Journals Fulltext of 17 trials comprising a total of 1133 subjects suggested that green tea consumption significantly reduced the fasting glucose and hemoglobin A1c (Hb A1c) concentrations by -0.09 mmol/L and -0.30%, respectively.

In the trials with high Jadad score studies, green tea significantly reduced fasting insulin concentrations -1.16 μIU/mL in compared to non green tea drinker group.

Other, in the mice study to evalaute green tea drink (T2 and T3) prepared by adding catechins and epigallocatechin gallate, major constituents isolated from green tea (EGCG) @ 550 mg/500 mL against non drinker group acted as control (T1), mice fed with T2 and T3 expressed a significant reduced cholesterol and LDL levels and serum glucose and insulin levels with no difference in all functional drink groups but control.

Dr. Ahmad RS, the lead author said, "In contrast to lipid profile, experimental drink containing EGCG reduced the trait better than catechins based functional drink".

Furthermore, the compared diabetic effects of 3 selected tea water extracts (TWE) and tea pomace extracts (TPE) and by on rat intestinal α-glucosidase activity in vitro as well as hypoglycemic effects in vivo, insisted that in male Sprague-Dawley (SD) rats fed with tea extracts improved levels of blood glucose level at 30 min after oral intake (0.5 g/kg body wt) in compared to the control in sucrose-loaded SD rat, probably through activation of antioxidants properties in free radical scavenging.

Indeed, tea pomace extract in the study exerted a significantly inhibition of intestinal α-glucosidase, in delayed glucose absorption resulting in suppressing postprandial hyperglycemia.

No doubtfully, green tea processed bioactives may be used as potentially nutraceutical products in prevent the risk of hyperglycemia in healthy people and early onset of in people with prediabetes.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Effect of green tea on glucose control and insulin sensitivity: a meta-analysis of 17 randomized controlled trials by Liu K1, Zhou R, Wang B, Chen K, Shi LY, Zhu JD, Mi MT.(PubMed)
(2) Preventive role of green tea catechins from obesity and related disorders especially hypercholesterolemia and hyperglycemia by Ahmad RS1, Butt MS2, Sultan MT3, Mushtaq Z4, Ahmad S5, Dewanjee S6, De Feo V7, Zia-Ul-Haq M8.(PubMed)
(3) Selected tea and tea pomace extracts inhibit intestinal α-glucosidase activity in vitro and postprandial hyperglycemia in vivo by Oh J1, Jo SH2, Kim JS3, Ha KS4, Lee JY5, Choi HY6, Yu SY7, Kwon YI8, Kim YC9(PubMed)

Food Therapy: Coffee and Coffee Caffeine, A Potent Mediator of Sex Hormones?

By Kyle J. Norton

In compared to herbal medicine, food therapy even takes longer, sometimes more than six months to ease the symptoms, depending to stages of the treatment which directly address to the cause of disease.

Coffee, a popular and social beverage all over the world, particularly in the West, is a drink made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.

Sex hormones are a class of hormones, affecting sexual development or reproduction. Steroid-binding globulin(SSBG), is a sex hormone, having a direct effect on androgen and estrogen.

A recent study suggested that coffee may have a direct effect in influence the production of sex hormone estrogen and testosterone depending to gender difference.

In a 8-week parallel-arm randomized controlled trial with Healthy adults (n = 42) recruited from the Boston community, including regular coffee consumers, nonsmokers, and overweight, randomized to five 6-ounce cups of caffeinated or decaffeinated instant coffee or water per day, at 4 weeks, researchers surprisingly found that
1. Decaffeinated coffee drinking was associated with a borderline significantly increased levels of SHBG in women, but not in men.
2. At week 4, decaffeinated coffee decreased total and free testosterone and caffeinated coffee decreased only total testosterone in women.
3. Contrasted to women participants, men consumption of caffeinated coffee displayed a significantly increased total testosterone and decreased total and free estradiol hormones.
4. The study also indicated that caffeinated coffee consumption do not exert any effect on SHBG in either men or women.

But conflicted to the healthy young adult, coffee and coffee caffeine showed an elevated effect as a mediator of sex hormone-binding globulin in both androgen and estrogen in type 2 diabetic patients, particularly in women.

Additionally, according to the cross-sectional study of 2377 nondiabetic pre- and postmenopausal women from the E3N cohort study in a multivariate adjusted model, intake of more than 3 cup of coffee daily coffee and caffeine ≥265 mg/day were associated with an increased SHBG level distribution (<46.3 nmol/L), in compared to no risk association of decaffeinated coffee subgroup.

Further more, the prevention of low level of SHBG of both caffeinated coffee and caffeine, may demonstrate a potential and positive effect in reduced risk of T2DM..

More importantly, in the examine a study during a median follow-up of 10 years of 359 postmenopausal women with newly diagnosed type 2 diabetes matched with 359 control subjects by age, race, duration of follow-up, and time of blood draw, coffee and caffeine were associated to increased levels of fee and total testosterone among postmenopausal women.

The finding evidences suggested that coffee and caffeine has a extreme effect in exhibition of sex hormone estrogen and testosterone through lower level of SHBG in menopause women and prevented onset of type 2 diabetes.
Decaffeinated coffee decreased total and free testosterone through significantly increased levels of SHBG in women. And caffeinated coffee displayed a significantly increased total testosterone and decreased total and free estradiol in men.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Author biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) The effects of caffeinated and decaffeinated coffee on sex hormone-binding globulin and endogenous sex hormone levels: a randomized controlled trial by Wedick NM1, Mantzoros CS, Ding EL, Brennan AM, Rosner B, Rimm EB, Hu FB, van Dam RM.(PubMed)
(2) Cross-sectional association of coffee and caffeine consumption with sex hormone-binding globulin in healthy nondiabetic women by Pihan-Le Bars F1,2, Gusto G3,4,5, Boutron-Ruault MC3,4,5, Fagherazzi G3,4,5, Bonnet F1,2,3.(PubMed)
(3) Coffee and caffeine consumption in relation to sex hormone-binding globulin and risk of type 2 diabetes in postmenopausal women by Goto A1, Song Y, Chen BH, Manson JE, Buring JE, Liu S.(PubMed)

Alternative Therapy: Yoga in Reduced Symptoms of All Aspects of Patients with Multiple Sclerosis

By Kyle J. Norton

Yoga therapy is found to associate to reduced physical and mental disability and improved quality of life in patients with moderate multiple sclerosis, a recent study suggested.

Multiple sclerosis is chronic and progressive condition involving damage to the sheaths of nerve cells in the brain and spinal cord.

Yoga, the accident technique practice for harmonized external and internal body well being, through breath control, meditation, bodily movement and gesture..... has been well known for people in Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

In a single-group design with repeated measurements at baseline, postintervention, and 8-week follow-up, patients with multiple sclerosis showed a hugh improvement in SF-36 MCS(Short Form Health Status Survey Mental Component Summary), MFIS(Modified Fatigue Impact Scale), BLCS(Bladder Control Scale), Perceived Deficits Questionnaire (PDQ), Mental Health Inventory (MHI) and Multiple Sclerosis Walking Scale (MSWS-12) and (Time 25 feet walking)T25FW,........ in followup examination compared to baseline.

The study also indicated that a strong effect in improvement of quality of life in patient attending yoga class, through out the study period without incurring any side effects.

According to the Oregon State University, mind-body therapies such as yoga practice of yoga may be a safe and effective way of managing symptoms of MS, including fatigue, imbalance, spasticity, chronic pain, cognitive impairment, bladder and bowel dysfunction, visual and speech impairments, depression, sensory disturbance, and mobility impairment.....

Dr. Rogers KA, the lead author also suggested that yoga may be used as an alternative treatment in management of symptoms of declining physical, emotional, and psychological symptoms for individuals with MS.

Furthermore, in an open arm, pre-post study design assessed the outcome measures at base line and after 21 days of integrated Yoga intervention with preparatory yogic loosening and breathing practices, with Nadishuddi pranayama (alternate nostril breathing), moola bandha (anal lock), kapalbhati (rapid nostril breathing) and deep relaxation technique given for 2h per day, after treatment, participants group showed a strong performance as indicated in the scores on post void residual urine (62.34%, p<0.05), parturition frequency checklist (25%, p<0.05), incontinence impact questionnaire-7 (32.77%, p<0.05) and uro-genital distress inventory-6 (26.33%, p<0.05).

The study also suggested that yoga intervention therapy may be used as an adjunct to standard care for treatment in multiple sclerosis patients with neurogenic bladder dysfunction without side effects.

Collectively, yoga may have a potential effect in reduced symptoms of patient with multiple sclerosis, but conditions should be mentioned to your yoga instructor before commencing.

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Feasibility and Impact of an 8-Week Integrative Yoga Program in People with Moderate Multiple Sclerosis-Related Disability: A Pilot Study by Cohen ET, Kietrys D, Fogerite SG, Silva M, Logan K, Barone DA, Parrott JS.(PubMed)
(2) Therapeutic Yoga: Symptom Management for Multiple Sclerosis by Rogers KA1, MacDonald M1.(PubMed)
(3) Effect of integrated Yoga on neurogenic bladder dysfunction in patients with multiple sclerosis-A prospective observational case series by Patil NJ1, Nagaratna R, Garner C, Raghuram NV, Crisan R.(PubMed)

Food Therapy: Coffee Caffeine Withdrawal Symptoms, Is It True?

By Kyle J. Norton

In compared to herbal medicine, food therapy even takes longer to ease symptoms, depending to stage of the treatment which directly address to the cause of disease.

Abruptively abstained caffeine intake may cause some withdrawal symptoms in regular and daily coffee caffeine intakers, the American University study suggested.
Coffee, second to tea, is a popular and social beverage all over the world, particular in the West, made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.

Coffee withdrawal symptoms is a set of the unpleasant physical condition caused by ceasing intake of additive caffeine for long term coffee lovers.

In a study of caffeine consumers (N=213) completed the CWSQ after 16h of caffeine abstinence, researchers at the above institute found that general withdrawal symptoms in participants included (1) Fatigue/drowsiness; (2) Low alertness/difficulty concentrating; (3) Mood disturbances; (4) Low sociability/motivation to work; (5) Nausea/upset stomach; (6) Flu-like feelings; and (7) Headache.

Regular and daily coffee intake group showed a significant and greater effect in symptoms of fatigue/drowsiness, low alertness/difficulty concentrating, mood disturbances, and headache in compared to group of non coffee caffeine drinkers.

Other, in the study of genetic effect, related to caffeine content of a beverage on caffeine withdrawal, suggested that withdrawal symptoms may be exaggerated in people who believe that certain genes may have a great influence in increased caffeine withdrawal and people with psychological belief that consumed caffeine leads to a reduction in withdrawal symptoms when no caffeine is consumed.

According to the returned questionnaire from participants 24 hours after caffeine abstinence, then given a cup of decaffeinated coffee, half the participants were told that their coffee was caffeinated participants displayed a strong belief of a greater reduction in withdrawal symptoms than those told it was decaffeinated. And genetic testing demonstrated a result information produced no difference in reported withdrawal symptoms.

In support to the above analysis, the study conducted by the University of Sydney, School of Psychology, using caffeine as a model to test the effect of expectancy on withdrawal symptoms, specifically whether the belief that one has ingested caffeine is sufficient to reduce caffeine withdrawal symptoms and cravings in abstinent coffee drinkers by using the same method as in above study, found that a similar result of greater reduction in the factors of cravings, fatigue, lack of alertness and flu-like feelings of the CWSQ, than those in the Told Decaf condition.

The finding evidences indicated that genetic and psychological and personal belief have a great affect in caffeine withdrawal symptoms, especially cravings, when no caffeine was consumed.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Development of the caffeine withdrawal symptom questionnaire: caffeine withdrawal symptomscluster into 7 factors by Juliano LM1, Huntley ED, Harrell PT, Westerman AT.(PubMed)
(2) Effect of Genetic Information and Information About Caffeine Content on Caffeine Withdrawal Symptoms by Mills L1, Dar-Nimrod I2, Colagiuri B2.(PubMed)
(3) Placebo caffeine reduces withdrawal in abstinent coffee drinkers by Mills L1, Boakes RA2, Colagiuri B2.(PubMed)

Tuesday, 3 October 2017

Food Therapy: Intake of Coffee In Ameliorated Risk of Primary Sclerosing Cholangitis

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

In compared to herbal medicine, food therapy may even take longer to ease symptoms, depending to stages of the treatment which directly address to the cause of disease.

Recent study suggested that coffee and caffeine consumption may be associated to reduced risk of primary sclerosing cholangitis

Primary sclerosing cholangitis (PSC) is a medical condition of inflammation and obliterative fibrosis of the bile ducts.

Coffee, a popular and social beverage all over the world, particular in the West, is a drink made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.

In the study of 606 patients with primary biliary cirrhosis (PBC), 480 with primary sclerosing cholangitis (PSC), and 564 healthy volunteers acted as controls, researchers filed the following results

1. 24% of patients with PSC had never drunk coffee in compared to 16% of controls.
2. Patients with PSC also consumed fewer lifetime cups per month and spent a smaller percentage of their lifetime drinking coffee in compared to healthy adults.

Base on these information, Dr.Lammert C, the lead author opinionated, coffee consumption is lower among patients with PSC, in compared with controls.

Additionally, In patients with PSC, recruited from Oslo University Hospital Rikshospitalet in Norway through 2011, randomly chosen from the Norwegian Bone Marrow Donor Registry (control subjects) of 240 patients with PSC and 245 control subjects also indicated a similar conclusion as follow
1. In compared to control, PSC patients showed a lower daily drinking coffee habit as the time of study and at the age of 18 years observed in men.
2. Ever daily coffee drinker at the age of 18 years were independently and negatively associated with PSC.

These result showed that coffee intake may have a profound effect in protection against development of PSC.

The finding evidences demonstrated that coffee and caffeine consumption may have a significant effect in attenuated risk of primary sclerosing cholangitis developing, but further large and multi centers studies are necessary to validate this claim.

Alternative Therapy: Yoga in Reduced Symptoms of Postural Stability and Improved Quality of Life in Patients with Schizophrenia

Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Yoga ameliorated symptoms and complications of patient with Schizophrenia, particular in improved postural stability, a renowned institute reported.

Schizophrenia is a mental disorder induced inconsistent or contradictory elements such as breakdown of certain relation in thought, emotion, and behavior, leading to faulty perception, inappropriate actions and feelings,....

Yoga, the ancient technique practice is used in parts of India to promote the body to heal itself through enhancing the physical and mental well being.

According to the Keio University School of Medicine, patients with schizophrenia-spectrum disorders showed a significant improvement in risk of falling that may lead to fractures, after attending the yoga lessons.

In an 8 week single-blind randomized controlled study with an eight-week follow-up of outpatients with schizophrenia or related psychotic disorder (ICD-10) randomly assigned to either yoga therapy or a control group, yoga treatment group expressed a significant improvement in a total length of trunk motion, the Romberg ratio(a set feature in the sensory organization test (SOT) as an indicator of proprioceptive contribution to postural stability), and ante flexion in standing after 8 weeks in compared control.

Dr. Ikai S, the lead author said, "the beneficial effects of the yoga therapy on postural stability in patients with schizophrenia. However, the therapeutic effects seemed transient, which warrants further investigations on strategies to sustain the improvements.".

Furthermore, in the review of the data base of the Cochrane Schizophrenia Group Trials Register (December 2008), based on regular searches of CINAHL, EMBASE, MEDLINE and PsycINFO,
yoga had a better outcome for mental state as well as physical health improved significantly in the exercise group compared to those in standard care.

The study also indicated that beside enhanced mental and physical well being, yoga therapy also improved the quality of life in patients with schizophrenia.

Taking together, there is no doubt that yoga has a potential effect in reduced postural physical disability and promoted quality of life in patients with schizophrenia with no adverse effects.

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) Effects of yoga therapy on postural stability in patients with schizophrenia-spectrum disorders: a single-blind randomized controlled trial by Ikai S1, Uchida H, Suzuki T, Tsunoda K, Mimura M, Fujii Y.(PubMed)
(2) Exercise therapy for schizophreni by Paul Gorczynski1 and Guy Faulkner1(PubMed)

Food Therapy: Green Tea in Reduced Symptoms Severity and Treatment of Osteoarthritis

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Regular drinking of green tea may have a positive effect in reduced symptoms of pain and treatment of osteoarthritis, a study by respectable institute postulated.

Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world. However, as yin in nature herbal medicine ,or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory. But a slice of ginger will neutralize that adverse effects.

Osteoarthritis (OA), a form of arthritis, is a condition characterized by aging progression of wear and tear on a joint, affecting over 25 million people in the United States in alone

In a randomized open-label active-controlled clinical trial of 50 adults with osteoarthritis of knee allocated to receive the green tea extract (in dosage form of tablet) plus diclofenac tablet as "intervention group"; or: diclofenac tablet alone as "control group" for a period of four weeks, combination treated group exerted a significant improvement of physical function in compared to control.

Treatment group also expressed a similar progress in pain reduction during knee joint physical function in adults with osteoarthritis as in control group.

Additionally, in the compared the effect of curcuminoids extract, hydrolyzed collagen and green tea extract, in chondrocytes culture cell, researchers found that combination of all components score a enormous expression of reduced production of pro inflammatory cytokins through various mechanisms, including ameliorated free radical elucidation.

Furthermore, in the support of the above differentiation, the study in the investigation of a posttraumatic osteoarthritis (OA) mouse model tested with EGCG against progression of OA and relieve OA-associated pain, suggested that EGCG-treated mice promoted cartilage production against Safranin O, staining of the knee joint cartilage loss and cartilage erosion in compared to control group with no treatment.
Importantly, cartilage of treated mice also displays a significant reduction of gene in regulated degeneration of connective tissue as well as pathways involved promotional of tissues inflammation.

Additionally, pain score of treated mice also exhibited a significant enhancement in compared control group.

Taking together, there is no doubt that green tea process a therapeutic and integrated form for prevention and treatment of symptoms of pain as well as improved physical activity of OA patients through protection against cartilage degeneration.