Food Therapy: Coffee and Coffee Caffeine Elevated and Ameliorated Menopause Symptoms Differently

By Kyle J. Norton


In compared to herbal medicine, food therapy even takes longer to ease symptoms, depending to stages of the treatment which directly address to the cause of disease.

Menopause is a natural and biological progression of women at certain age. The reduced hormone levels of inaction of ovaries induced menstruation stop and a set of symptoms

Coffee, second to green tea, is a popular and social beverage all over the world, particular in the West, made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.

A study conducted by a renowned institute suggested that coffee nd coffee caffeine may have potential effect in reduced severity of some menopause symptoms and elevation of others.

In a cross-sectional survey conducted using the Menopause Health Questionnaire, completed by 2,507 consecutive women with menopausal concerns at the Women's Health Clinic at Mayo Clinic (Rochester, MN) between July 25, 2005 and July 25, 2011, caffeine intake in participants showed a greater positive effect in expression of vasomotor symptom of menopause women in compared to non drinkers group.

Other, in a cross-sectional study of a community-based sample of 243 women with vasomotor symptoms to evaluate the menopause symptoms of hot flashes (HF) and night sweats (NS) in symptomatic middle-aged women, intake of coffee showed to elevate symptom of hot flashes (HF) and night sweats (NS) in compared to non drinkers.

And caffeine intake also is found as one of predictor in  exhibited both hot flashes (HF) and night sweats (NS)  in the same study group.

But in animal model, according to the behavioral tests and oxidative stress parameters in ovariectomized mice, caffeine intake also showed a significant in reduced symptoms of anxiety induced by oxidative stress.

Administration of low doses of caffeine, for a short period of time, may be a new therapeutic approach to modulate the oxidative stress and anxiety in menopause, the "Iuliu Hatieganu" University of Medicine and Pharmacy postulated.

Taking altogether, coffee and coffee caffeine may have a strong effect in reduced and elevated menopause symptoms, in types depending manner.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half

Author biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Caffeine and menopausal symptoms: what is the association? by Faubion SS1, Sood R, Thielen JM, Shuster LT.(PubMed)
(2) Perceived control, lifestyle, health, socio-demographic factors and menopause: impact on hot flashes and night sweats by Pimenta F1, Leal I, Maroco J, Ramos C.(PubMed)
(3) Modulatory effects of caffeine on oxidative stress and anxiety-like behavior in ovariectomized rats by Caravan I1,1, Sevastre Berghian A1,1, Moldovan R1,1, Decea N1,1, Orasan R1,1, Filip GA1,1.(PubMed)

Food Therapy: Kidney bean, the Best Anti-cancer Healthy Whole Food

By Kyle J. Norton

Expectation of easing symptoms after a few days of herbal treatment, in most cases are ended with disappointment. Symptoms of the diseases can only be eased gradually, depending to stage of the treatment which directly addresses to the cause of the disease.

Kidney bean may have potential effects against irregular cell growth in the body, causing various types of cancer, a recent study proposed.

Kidney bean is popular food, with  kidney shape, strong flavor and color in reddish brown in nature, used often as an excellent dietary selection because of enormous health benefits with a good source of protein and minerals.

Cancer, a group of diseases characterized by cells growing and multiplying disordered and uncontrollable in our body. At the late stage, cancer cells may travel a distance away from the original site to invase other tissues and organs.

According to the joint study lead by the Shenzhen University, chemical compound 60-kDa glucosamine binding lectin, white kidney bean lectin (WKBL), showed an efficacy in inhibited HepG2 activity in compared to MCF7 cells through induced anti proliferative and anti apoptotic activities.

The study also found that epithelial tumor cell lines ( HONE-1) also are inhibited by chemical compound lectin in activation of various extrinsic apoptosis pathway involved cell death.

Dr. Chan YS, the lead author said, " The (anti proliferative) activity could be reduced by addition of glucosamine, which occupies the binding sites of WKBL, indicating that carbohydrate binding is crucial for the activity".

Beside chemical compound 60-kDa glucosamine binding lectin, 64-kDa glucosamine-specific lectin isolated from brown kidney bean also exhibited antiproliferative activity against nubers of cell lines including human breast cancer (MCF7) cells, hepatoma (HepG2) cells and nasopharyngeal carcinoma (CNE1 and CNE2) cells with concentration of an inhibitor of 5.12 µM, 32.85 µM, 3.12 µM and 40.12 µM respectively after treatment for 24 hours.

Particularly in breast cancer cell line MCF7, formation of apoptotic bodies of the tumors are associated to apoptosis involved estrogen receptor(ER) stress and directed protein response.

Taking together, Kidney bean processed an anti cancer effects by exhibited anti proliferative and anti apoptotic activities against the early stage of development and progression of the cancer in various pathway. Please note that raw kidney beans are toxic.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half  

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) White kidney bean lectin exerts anti-proliferative and apoptotic effects on cancercells by Chan YS1, Xia L2, Ng TB3.(PubMed)
(2) Isolation of a glucosamine binding leguminous lectin with mitogenic activity towards splenocytes and anti-proliferative activity towards tumor cells by Chan YS1, Wong JH, Fang EF, Pan W, Ng TB.(PubMed)

Food Therapy: Kidney bean, The Natural Whole Food with Anti-Microbial Activities

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over laast 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Expectation of easing symptoms after a few days of herbal treatment, in most cases are ended with disappointment. Symptoms of the diseases can only be eased gradually, depending to stage of the treatment which directly addresses to the cause of the disease.

Recently study conducted by renowned institute suggested that oral administrated kidney bean may have a potential health benefits in reduced risk and treatment of microbial infection.

Kidney bean is popular because of its kidney shape, strong flavor and color of reddish brown in nature, It is often an excellent dietary selection with no cholesterol and good sources of protein and mineral.

According to the research article posted at the Journal of Microbial & Biochemical Technology, lectins isolated from kidney bean seed displayed a significant antifungal and anti bacteria activity on many straits of Staphylococcus aureus ATCC 6538, and Streptococcus mutants ATCC 25175, Pseudomonas aeruginosa ATCC 10145 and Klebsiella pneumonia and Candida albican.

The chemical compound lectins also manifested inhibitory effects on human immunodeficiency virus-1 reverse transcriptase of enzymes in catalyzed the formation of RNA from a DNA and alpha-glucosidase in lower the rate of glucose absorption.

Dr. Ye XY, the lead author in the study said, " It(Lectins) exerted a suppressive effect on growth of the fungal species Fusarium oxysporum, Coprinus comatus, and Rhizoctonia solani".

Other researchers suggested that the potency of kidney bean in exhibited anti microbial effect may be a result of its source of nondigestible fermentable components and phenolic compounds. 

In  healthy mice exposed to dextran sodium sulphate (DSS) (via drinking water, 2% DSS w/v, 7 days) induced colitis and fed with one of three isocaloric diets: basal diet control (BD), or BD supplemented with 20% cooked white (WK) or dark red kidney (DK) bean flour for 3 weeks, mice fed with both bean diets reduced, significantly disease severity, colonic damage and exerted increased mRNA expression of antimicrobial effects involved innate immunity and protected mucosa from insults through stabilizing the mucus layer and promoted healing of the epithelium and reduced proinflammatory cytokins demonstration.

Furthermore, cooked white (WK) or dark red kidney (DK) bean fed mice also enhanced microbial-derived SCFA metabolite production in regulated fermentation products, gut barrier integrity and the microbial defensive response .....

Taking together, Kidney beans ( Phaseolus) showed to process a strong anti-microbial effect in reduced infection and inflammation caused by straits of bacteria and fungi, especially in protected the digestive system against inflammation cause of  colitis.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half  

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) Antimicrobial Activities of Lectins Extracted from Some Cultivars of Phaseolus vulgaris by SeedsEinas Hamed El-S1, Magda Mahmoud Ibrahim El-A2and Mervat Mounir S1(Journal of Microbial & Biochemical Technology)
(2) White and dark kidney beans reduce colonic mucosal damage and inflammation in response to dextran sodium sulfate by Monk JM1, Zhang CP1, Wu W2, Zarepoor L1, Lu JT1, Liu R2, Pauls KP3, Wood GA4, Tsao R2, Robinson LE5, Power KA6.(PubMed)
(3) Isolation of a homodimeric lectin with antifungal and antiviral activities from red kidney bean (Phaseolus vulgaris) seeds by Ye XY1, Ng TB, Tsang PW, Wang J.(PubMed)

Food Therapy: Coffee and Coffee Caffeine Intake and Risk of Gallstone and Gallstone Diseases

By Kyle J. Norton


In compared to herbal medicine, food therapy even takes longer to ease symptoms, depending to stages of the treatment which directly address to the cause of disease.

Epidemiological studies, linking coffee consumption in reduced risk of gallstone, but not gallstone disease have been contradictory.

Gallstone is a stone formed within the gallbladder out of bile components as a result of building up of undissolved cholesterol over a prolonged period of time.

Coffee, a popular and social beverage all over the world, particular in the West, made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.

In the review of 174 cases of gallstones determined by ultrasonography, 104 cases of postcholecystectomy, and 6889 controls of normal gallbladder in the total of 7637 men received a health examination at four hospitals of the Self-Defense Forces (SDF) with 174 cases of prevalent gallstones, 50 had been aware of having gallstones, researchers found that coffee and coffee caffeine drinkers express a high risk of gallstone incidence in compared to non drinkers.

In these group of middle-aged Japanese men, the relative odds ratios of gallstone disease 1.7 for coffee consumption of five cups or more per day vs. no consumption and 2.2 for caffeine intake of 300 mg/day or more vs. less than 100 mg/day.

Obviously, these findings contradicted to other studies in support of risk of gallstone reduced by coffee and caffeine intake, including the study conducted by Harvard School of Public Health.

Other, in the review literature of database from PubMed and EMBASE of all published studies before June 2015 researchers at The First Affiliated Hospital of Zhengzhou University files the following results
1. Coffee intake regularly and daily had a significantly reduced risk of gallstone disease, in related females, but not in males. based on prospective studies.

2. For patients drinking one cup of coffee per day, the risk of of gallstone disease was 0.95
3. For patients drinking 2, 4 and 6 cups of coffee per day, the estimated RRs of gallstone disease reduced to 0.89 (95% CI, 0.79 to 0.99), 0.81 and .75 respectively.
4, Coffee intake showed a linear association to ameliorated risk of gallstone diseases.

Interestingly, in a cohort of 80,898 women age 34-59 years in 1980 who had no history of gallstone disease, during 20 years of follow-up, researchers filed the below results
1. Compared to non caffeine coffee drinkers women, the multivariate relative risks of gallstone disease with cholecystectomy in compared to consistent intake of caffeinated coffee (0, 1, 2-3, and > or =4 cups/day) were 1.0, 0.91, 0.78, and 0.72 respectively.
2. Coffee caffeine intake was inversely associated to risk of cholecystectomy.
3. Caffeine intake (< or =25, 26-100, 101-200, 201-400, 401-800, and >800 mg/day) is linearly associated to reduced risk of gallstone disease with multivariate relative ratio of 1.0, 1.03, 1.01, 0.94, 0.85, and 0.85 4. Decaffienated coffee was not associated with risk.

There is no doubt that the study addresses a significantly inverse association in reduced risk of gallstone disease among coffee drinkers linearly.

Taking altogether, the contradictory result may warrant a further study, before one can make a decision of the effect of coffee and coffee caffeine in concern of risk of gallstone, but not in the attnuated risk of symptomatic gallstone disease.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Lossu

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Relation of coffee, green tea, and caffeine intake to gallstone disease in middle-aged Japanese men by Ishizuk H1, Eguchi H, Oda T, Ogawa S, Nakagawa K, Honjo S, Kono S.(PubMed)
(2) Systematic review with meta-analysis: coffee consumption and the risk of gallstone disease by Zhang YP1, Li WQ1, Sun YL1, Zhu RT1, Wang WJ1.(PubMed)
(3) A prospective study of coffee consumption and the risk of symptomatic gallstone disease in men by Leitzmann MF1, Willett WC, Rimm EB, Stampfer MJ, Spiegelman D, Colditz GA, Giovannucci E.(PubMed)

Food Therapy: Black Bean, A Potent Chronic Diseases Functional Food

By Kyle J. Norton

People who turn to alternative medicine for treatment of disease in avoidance of adverse effects induced by conventional medicine should be patient. In compared to herbal medicine; food therapy even takes longer to ease symptoms, depending to stages of the treatment which directly address to the cause of disease.

Intake black bean regularly may have a potential effect in attenuated risk and treatment of chronic diseases.

Chronic diseases, not prevented by vaccines or cured by medication are any diseases last over 3 months or more.

Black bean, a small roughly ovoid legumes with glossy black shells, genus Phaseolus, belongings to the family Fabaceae can be bought in most grocery stores all around the year in dried and canned forms. It is believed that black bean was first domesticated growth in South America.

According to the University of Colorado Colorado Springs, the efficacy of legume in reduced chronic illness risk may be attributed to antioxidant phytochemical activities as well as other responses influenced the classification to types of diseases such as diabetes, CVD and cancer.

In protein and four synthesized pure peptides isolated Mexican black and Brazilian Carioca bean showed a potential and therapeutic effect in treating antidiabetic and antihypertensive mice regardless of their antioxidant capacity.

In fact, according to the Universidad Complutense de Madrid, types of carbohydrates found in black bean may be associated with a low glycemic response, low serum cholesterol levels, and a decrease of colon cancer risk factors as well as other forms of in chronic diseases such as diabetes type II and cardiovascular diseases.

Collectively, black bean reduced risk and treatment of chronic illness are the result of improved antioxidant status and other mechanisms, including reduction of glucose, triglycerides, total cholesterol, llower levels of LDL and Raised HDL as well as protecting pancreatic ß-cells, ...

Taking together, there is no doubt that black bean may be used as functional foods in attenuated risk and treatment of chronic disease, through antioxidant, anti inflammatory, anti profilerative, cardioprotective..... activities.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Biography

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Phaseolus beans: impact on glycaemic response and chronic disease risk in human subjects by Hutchins AM1, Winham DM, Thompson SV.(PubMed)
(2) Characterization of peptides from common bean protein isolates and their potential to inhibit markers of type-2 diabetes, hypertension and oxidative stress by Mojica L1,2, Luna-Vital DA1,3, González de Mejía E1.(PubMed)
(3) [Role of black bean Phaseolus vulgaris on the nutritional status of Guatemalan population].
[Article in Spanish]by Serrano J1, Goñi I.(PubMed)

Food Therapy: Coffee, A Potent Functional Food in Attenuated Risk of Metabolic Syndrome

By Kyle J. Norton

In compared to herbal medicine, food therapy even takes longer to ease symptoms, depending to stages of the treatment which directly address to the cause of disease.

Metabolic Syndrome is a group of risk factors associated with the development of cardiovascular disease and type 2 diabetes, including high blood pressure, abnormal high blood cholesterol and triglyceride levels,.....

A joint study by respectable institutes suggested that intake of coffee and coffee caffeine daily and regularly may associate to attenuated risk of metabolic syndrome.

Coffee, second to green tea, is a popular and social beverage all over the world, particular in the West, made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.

According to the searching of database from f PubMed and the China National Knowledge Infrastructure (CNKI) for relevant articles published between 1 January 1999 and 31 May 2015, including 11 published reports and 13 studies with a total of 159,805 participants were eligible for our meta-analysis, the relative odd risk ratio of metabolic syndrome  between the highest vs lowest category of coffee consumption was 0.872 

The review also observed a non linear relationship between coffee and coffee caffeine consumption in ameliorated risk of metabolic syndrome, by dose-response analysis.

Additionally, in a cross-sectional population-based survey of 8,821 adults (51.4% female) conducted in Krakow, Poland. to evaluate the coffee and tea consumption and risk of metabolic syndrome, using food frequency questionnaires, observation of the questionnaire returned from participants expressed an interesting association between high coffee consumption of 3 cups and the clusters of lower BMI, waist circumference, systolic and diastolic blood pressure, triglycerides, and higher HDL cholesterol than those drinking less than 1 cup/day.

The study apparently indicated that people drinking 3 cups of coffee daily and regularly have a favorably ameliorated risk of metabolic syndrome even after adjusting for potential confounding factors.

More importantly, the study also pointed out that high coffee consumption was negatively associated with waist circumference, hypertension, and triglycerides in women but not in men.

Furthermore, in animal evaluation of the effect of coffee drinking on clinical markers of diabetes and metabolic syndrome in Zucker rats including Diabetic Zucker rats with metabolic syndrome and control Zucker rats, researchers at the Fluminense Federal Institute postulated that after animals received daily doses of coffee drink by gavage for 30 days, coffee consumption expressed a decreased risk of metabolic syndrome in reduced serum glucose, total cholesterol and triglycerides in compared to non treatment group.

Dr. Abrahão SA, the lead researchers said, "The results demonstrate that treatment with roasted coffee drink, because of its hypoglycemic and hypolipidemic effect, is efficient in the protection of animals with metabolic syndrome and diabetes mellitus type 2".

The findings from above studies suggested that coffee and coffee caffeine drinking daily and regularly have a favorably profound effect in decreased risk of metabolic syndrome, particular in women.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half

Author Biopraphy
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Coffee consumption and risk of the metabolic syndrome: A meta-analysis by Shang F1, Li X1, Jiang X2.(PubMed)
(2) Association of daily coffee and tea consumption and metabolic syndrome: results from the Polish arm of the HAPIEE study by Grosso G1,2, Stepaniak U3, Micek A3, Topor-Mądry R3, Pikhart H4, Szafraniec K3, Pająk A3.(PubMed)

Food Therapy: Black Bean, The Best Functional Food for Hypertension

By Kyle J. Norton

People who turn to alternative medicine for treatment of disease in avoidance of adverse effects induced by conventional medicine should be patient. In compared to herbal medicine; food therapy even takes longer to ease symptoms, depending to stages of the treatment which directly address to the cause of disease.

Adding a portion of cooked black bean in your diet may substantially.reduce risk and enhanced treatment of hypertension, a respectable universities study suggested.

Hypertension is medical syndrome characterized by abnormal high blood pressure, affecting high portions of population in the world, according to statistic.

Black bean, a small roughly ovoid legume with glossy black shells, genus Phaseolus, belongings to the family Fabaceae can be bought in most grocery stores all around the year in dried and canned forms. It is believed that black bean was first domesticated growth in South America.

According to the joint study lead by the University of Illinois at Urbana-Champaign, Mexican black bean isolated proteins peptidase-IV (DPP-IV), after pepsin/pancreatin digestion, showed a significant effect in reduced hypertension at dose with IC50 = 0.03-0.87 mg and dry weight and inhibited α-glucosidase, a protein related to early onset of diabetes, ranged from 36.3 to 50.1% mg-1 DW.

The efficacy of the anti hypertension of the black bean is attributed to the elevation of antioxidant capacity fighting against forming of reactive oxygen species (ROS), Dr. Mojica L, the lead author insisted.

In an article published at the Research Journal of Pharmaceutical, Biological and Chemical Sciences,
black bean crude extract decreased both systolic as well as diastolic BP in a dose-dependent manner (1-100 mg/kg).

The article also indicated that the fall of both pressure may be due to presence of phytochemicals saponin fraction and medicogenic acid glucoside in the crude extract.

Further more, azuki bean (Vigna angularis) seed coats (ABSC) with different color, containing high amount of polyphenols attenuated vascular oxidative stress and inflammation associated with hypertension in experiment of hypertensive rats (SHR) and control normotensive Wistar-Kyoto (WKY) rats.

More importantly, treated mice with azuki bean (Vigna angularis) seed coats (ABSC), suppressed the elevation of SBP throughout the treatment period of 8 weeks, by decreasing of NADPH pxidase in activated free radical expression and increasing antibody p47phox and Nox4 against radical formation through mRNA expression.

Dr. Mukai Y, the lead researcher said, " polyphenol-containing ABSC could attenuate vascular oxidative stress and inflammation during the progression of hypertension, and this may lead to an improvement in hypertension".

The findings suggested that black bean with various chemical constituents may be considered as a functional and integrated food for reduced hypertensive risk and treatment of high blood pressure.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1)  Characterization of peptides from common bean protein isolates and their potential to inhibit markers of type-2 diabetes, hypertension and oxidative stress by Mojica L1,2, Luna-Vital DA1,3, González de Mejía E1.(PubMed)
(2) Comparative Review on Harmless Herbs with Allopathic Remedies As AntiHypertensive by  Joshi UH*, Ganatra TH, Bhalodiya PN, Desai TR, Tirgar PR(Research Journal of Pharmaceutical, Biological and Chemical Sciences)
(3) Polyphenol-containing azuki bean (Vigna angularis) seed coats attenuate vascular oxidative stress and inflammation in spontaneously hypertensive rats by Mukai Y1, Sato S.(PubMed)