Posted By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research
papers have been written and published on line, including world wide
health, ezine articles, article base, healthblogs, selfgrowth, best
before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by
Disilgold.com Named 50 of the best health Tweeters Canada - Huffington
Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as
international journal Pharma and Bio science, ISSN 0975-6299.
Recipes contributed by Company's Coming Salads by Jean Pare
Choose iceberg lettuce or Chinese cabbage
Tarragon dressing
Sour cream 1/2 cup (125ml)
Tarragon vinegar 1tbsp. (15ml)
granulated sugar 2 tsp. (10ml)
Onion salt 1/2 tsp. (2ml)
Paprika 1/2 tsp. (2ml)
Salad
Lettuce chunks or wedges 6
Sliced green onion or thinly sliced onion ring 1/2 cup (125 ml)
Tarragon Dressing: Combined all 5 ingredients in a small bowl. Mix well
Salad: Arrange lettuce chunk on small size salad plate. Scatter onions over top. Spoon dressing over top, and serve. Serve 6
Variation: spoon French or thousand Island dressing over lettuce wedges.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
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The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome: The Fertility Herb White willow
By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovasular disease(8)(13), acne(10)(14), endometrial cance(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasing altered glucose tolerance(20), CVD and hypertension(21).
The prevention and management In Herbal Medicine
Polycystic ovary syndrome (PCOS) is unpreventable in Western medicine. Early diagnosis and treatment may reduce risk of its complications, including infertility, metabolic syndrome, obesity, diabetes, cardiovascular diseases, stroke, etc.
Reduce fat intake less than 30% of total calories with a low proportion of saturated fat and high in fiber from predominantly low-glycaemic-index-carbohydrate foods for patients with PCOs(827a). Calorie intake should be distributed between several meals per day with restricted intake of snacks and drinks(828).
The Fertility Herb: White willow
White willow is also known as salix alba in herbal medicine, native to Europe and western and central Asia, used in traditional medicine as pain reliever(1007)(1008), anticancer(1009)(1010), antimicrobial(1013), antioxidant(1014)(1015), anti-inflammatory(1011)(1012) and fertility enhancing herb(1016).
1, Antiestrigenic effects
White willow processes antiestrigenic effects(1017) by blocking proliferation in hypersensitive cells (1018) which cause estrogenic diseases, including breast cancer(1019) and metabolism imbalance(1020) diseases, such as obesity and diabetes(1021).
2. Salicylic acid
Salicylic acid, a chemical compound converted from salincin found abundantly in white willow has shown to process anti acne(1022)(1023) one of many symptoms of PCOs) effects, probably through its antioxidant activity(1026) in blocking elevated production of sebum by hyperactive sebaceous glands and blockage of the follicle(1022). According to Telemark Hospital, the acid may also be beneficiary for increased the clinical pregnancy rate when used conjunction with vitro fertilisation (IVF)/intra-cytoplasmic sperm injection (ICSI)(1024) and protective against fetal losses(1025), through its anti antithrombotic property(1025). The synthetic version of salicylic acid has also shown to consisting aspirin's cardioprotective effects through its antithrombotic and anti-inflammatory actions(1027).
3. Immune system
The antioxidant(1028)(1029) and anti inflammatory(1030)(1031) effects of white willow enhance immune system fighting against microbial invasion and guarding our body DNA integrity(1033) against irregular cell growth(1032)(1033) through inhibiting the effect of intermediate enzymes and other mechanisms(1027)
d. Vitamin C
Natural vitamin polypeptide C white willow found in white willow not only is found to consist the weight loss property(See the weight loss vitamin C)[
Vitami C found abundantly in red clover has shown strong evidneces epidemiologically in reducing weight loss for obese population, espexially for obese women with PCOs.
See The weight loss vitamin C for more details
[Vitamin C and other nutrients deficiency not only is associated to the risk of Obesity(807) but also enhances the risk of lipids, inflammation and insulin resistance(808).
According to the research team at Universidad Autónoma de Querétaro, there is an associated link between Obesity and Zinc and vitamins A and C concentration in in women from rural Mexico, in a fasting blood sample analysis (809).
Although genetic susceptibility to obesity is associated with gene polymorphisms affecting biochemical pathways which also impacted by specific foods and nutrients. According to Dr. Johnston CS., vitamin C depletion is associated to positively related to body mass, individuals with adequate vitamin C status oxidize 30% more fat during a moderate exercise bout than individuals with low vitamin C status(810)
Vitamin C, the protective effect against obesity
Endothelial dysfunction has found to be associated to the incidence of obesity(811). The study of 76 healthy subjects (50 men and 26 women aged 21-45 years) obese subject, showed a positive effect of vitamin C and indomethacin in reduced oxidative stress contributed to endothelial dysfunction in human obesity(812).
In the evaluation of the potential inhibitory activity on α-glucosidase and pancreatic lipase by Citrus spp. fruits of Spanish origin, grapefruit, contained higher contents of phytochemicals such as vitamin C, is found to have a great value for nutrition and treatment of diet-related diseases(813).
L-Ascorbic acid in the study, whether would facilitate the anti-obesity effects of chitosan and psyllium husk in vivo, showed addition of vitamin C in diet influenced the reduction in body weight gain and food efficiency ratio, and the increase in total fecal weight and fecal fat excretion in guinea pigs fed a high-fat diet(814)]
but also improves the immune function in fighting against the forming of free radicals(1034) and foreign invasion(1035) but also increases the blood flow to the reproductive organ(1036)(1037)(1038) through reducing oxidant stress, increasing NO bioavailability(1037) of which may reduce risk sexual libido(1038) and enhance the chance of conception(1039)(1040)(1041).
Side effects
1. Risk of anaphylactic reaction to patients with a history of allergy to salicylates(1042).
2. Over dose of white willow may cause digestive disorder such as nausea and stomachache(1044)
3. Do not use the herb(1043)
a. If you are aspirin allergy/sensitivity,
b. If you are taking anticoagulants or "blood thinners," and
c. On children with flu-like symptoms or Reye's syndrome.
Ovarian Cysts And PCOS Elimination
References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndrome and healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(827a) Diet and nutrition in polycystic ovary syndrome (PCOS): pointers for nutritional management by Farshchi H, Rane A, Love A, Kennedy RL(PubMed)
(828) The optimal diet for women with polycystic ovary syndrome? by Marsh K, Brand-Miller J.(PubMed)
(1009) In vitro anti-proliferative effects of the willow bark extract STW 33-I by Bonaterra GA1, Kelber O, Weiser D, Metz J, Kinscherf R.(PubMed)
(1010) Willow leaves' extracts contain anti-tumor agents effective against three cell types by El-Shemy HA1, Aboul-Enein AM, Aboul-Enein KM, Fujita K.(PubMed)
(1011) Mechanisms involved in the anti-inflammatory effect of a standardized willow bark extract by Khayyal MT1, El-Ghazaly MA, Abdallah DM, Okpanyi SN, Kelber O, Weiser D.(PubMed)
(1012) Amelioration of collagen-induced arthritis by Salix nigra bark extract via suppression of pro-inflammatory cytokines and oxidative stress by Sharma S1, Sahu D, Das HR, Sharma D.(PubMed)
(1013) Antimicrobial effects of Finnish plant extracts containing flavonoids and other phenolic compounds by Rauha JP1, Remes S, Heinonen M, Hopia A, Kähkönen M, Kujala T, Pihlaja K, Vuorela H, Vuorela P.(PubMed)
(1014) The study of interactions between active compounds of coffee and willow (Salix sp.) bark by water extract. Durak A1, Gawlik-Dziki U1.(PubMed)
(1015) Willow bark extract increases antioxidant enzymes and reduces oxidative stress through activation of Nrf2 in vascular endothelial cells and Caenorhabditis elegans by Ishikado A1, Sono Y, Matsumoto M, Robida-Stubbs S, Okuno A, Goto M, King GL, Blackwell TK, Makino T.(PubMed)
(1016) What Your Doctor May Not Tell You About(TM) Getting Pregnant: Boost Your ... By Raymond Chang, Elena Oumano
(1017) antiestrigenic effectsof bee pollen from Cystus incanus and Salix alba as evaluated by the yeast estrogen screen and the micronucleus assay in human lymphocytes by Pinto B1, Caciagli F, Riccio E, Reali D, Sarić A, Balog T, Likić S, Scarpato R.(PubMed)
(1018) Adaptive hypersensitivity to estrogen: mechanisms and clinical relevance to aromatase inhibitor therapy in breast cancer treatment by Santen RJ1, Song RX, Zhang Z, Kumar R, Jeng MH, Masamura S, Lawrence J Jr, MacMahon LP, Yue W, Berstein L.(PubMed)
(1019) Transcriptional implications of intragenic DNA methylation in the oestrogen receptor alpha gene in breast cancer cells and tissues by Shenker NS1, Flower KJ2, Wilhelm-Benartzi CS3, Dai W4,5, Bell E6, Gore E7, El Bahrawy M8, Weaver G9, Brown R10, Flanagan JM11.(PubMed)
(1020) Sex hormone imbalances and adipose tissue dysfunction impacting on metabolic syndrome; a paradigm for the discovery of novel adipokines by Zhang H, Sairam MR.(PubMed)
(1021) Metabolic Balance for Maximum Health 6/06 June 6, 2006 - - + Juvenon Health Journal Vol. 5 No. 6, June 2006
(1022) [Use of organic acids in acne and skin discolorations therapy].[Article in Polish]by Kapuścińska A1, Nowak I1.(PubMed)
(1023) Rapid treatment of mild acne with a novel skin care system containing 1% salicylic acid, 10% buffered glycolic acid, and botanical ingredients by Bhatia AC, Jimenez F.(PubMed)
(1024) Do acetyl salicylic acid and terbutaline in combination increase the probability of a clinical pregnancy in patients undergoing IVF/ICSI by Hanevik HI1, Friberg M, Bergh A, Haraldsen C, Kahn JA.(PubMed)
(1025) Efficacy of three different antithrombotic regimens on pregnancy outcome in pregnant women affected by recurrent pregnancy loss by Giancotti A1, La Torre R, Spagnuolo A, D'Ambrosio V, Cerekja A, Piazze J, Chistolini A.(PubMed)
(1026) Clinical evidence on the efficacy and safety of an antioxidant optimized 1.5% salicylic acid (SA) cream in the treatment of facial acne: an open, baseline-controlled clinical study by Zheng Y1, Wan M, Chen H, Ye C, Zhao Y, Yi J, Xia Y, Lai W.(PubMed)
(1027) Molecular targets of aspirin and cancer prevention by Alfonso L1, Ai G2, Spitale RC3, Bhat GJ2.(PubMed)
(1028) Effects of salicylic acid and putrescine on storability, quality attributes and antioxidant activity of plum cv. 'Santa Rosa' by Davarynejad GH1, Zarei M1, Nasrabadi ME1, Ardakani E1.(PubMed)
(1029) Salicylic acid promotes seed germination under high salinity by modulating antioxidant activity in Arabidopsis by Lee S1, Kim SG, Park CM.(PubMed)
(1030) An in vivo study examining the antiinflammatory effects of chamomile, meadowsweet, and willow bark in a novel functional beverage by Drummond EM1, Harbourne N, Marete E, Jacquier JC, O'Riordan D, Gibney ER.(PubMed)
(1031) Inhibition of proinflammatory biomarkers in THP1 macrophages by polyphenols derived from chamomile, meadowsweet and willow bark by Drummond EM1, Harbourne N, Marete E, Martyn D, Jacquier J, O'Riordan D, Gibney ER.(PubMed)
(1032) Willow bark extract (BNO1455) and its fractions suppress growth and induce apoptosis in human colon and lung cancer cells by Hostanska K1, Jürgenliemk G, Abel G, Nahrstedt A, Saller R.(PubMed)
(1033) In vitro anti-proliferative effects of the willow bark extract STW 33-I. by Bonaterra GA1, Kelber O, Weiser D, Metz J, Kinscherf R.(PubMed)
(1034) Comprehensive study on vitamin C equivalent antioxidant capacity (VCEAC) of various polyphenolics in scavenging a free radical and its structural relationship by Kim DO1, Lee CY.(PubMed)
(1035) Structure, mechanism and regulation of an artificial microbial ecosystem for vitamin C production by Zou W1, Liu L, Chen J.(PubMed)
(1036) Melatonin and vitamin C increase umbilical blood flow via nitric oxide-dependent mechanisms by Thakor AS1, Herrera EA, Serón-Ferré M, Giussani DA.(PubMed)
(1037) Tetrahydrobiopterin, L-arginine and vitamin C act synergistically to decrease oxidant stress and increase nitric oxide that increases blood flow recovery after hindlimb ischemia in the rat by Yan J1, Tie G, Messina LM.(PubMed)
(1038) Protective role of ascorbic acid to enhance reproductive performance of male rabbits treated with stannous chloride by Yousef MI1.(PubMed)
(1039) Efficacy of vitamin C and ethanolic extract of Sesamum indicum in promoting fertility in male Wistar rats by Ashamu E1, Salawu E, Oyewo O, Alhassan A, Alamu O, Adegoke A.(PubMed)
(1040) Vitamin C--the primate fertility factor? by Millar J1.(PubMed)
(1041) Promoting extracellular matrix remodeling via ascorbic acid enhances the survival of primary ovarian follicles encapsulated in alginate hydrogels by Tagler D1, Makanji Y, Tu T, Bernabé BP, Lee R, Zhu J, Kniazeva E, Hornick JE, Woodruff TK, Shea LD.(PubMed)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovasular disease(8)(13), acne(10)(14), endometrial cance(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasing altered glucose tolerance(20), CVD and hypertension(21).
The prevention and management In Herbal Medicine
Polycystic ovary syndrome (PCOS) is unpreventable in Western medicine. Early diagnosis and treatment may reduce risk of its complications, including infertility, metabolic syndrome, obesity, diabetes, cardiovascular diseases, stroke, etc.
Reduce fat intake less than 30% of total calories with a low proportion of saturated fat and high in fiber from predominantly low-glycaemic-index-carbohydrate foods for patients with PCOs(827a). Calorie intake should be distributed between several meals per day with restricted intake of snacks and drinks(828).
The Fertility Herb: White willow
White willow is also known as salix alba in herbal medicine, native to Europe and western and central Asia, used in traditional medicine as pain reliever(1007)(1008), anticancer(1009)(1010), antimicrobial(1013), antioxidant(1014)(1015), anti-inflammatory(1011)(1012) and fertility enhancing herb(1016).
1, Antiestrigenic effects
White willow processes antiestrigenic effects(1017) by blocking proliferation in hypersensitive cells (1018) which cause estrogenic diseases, including breast cancer(1019) and metabolism imbalance(1020) diseases, such as obesity and diabetes(1021).
2. Salicylic acid
Salicylic acid, a chemical compound converted from salincin found abundantly in white willow has shown to process anti acne(1022)(1023) one of many symptoms of PCOs) effects, probably through its antioxidant activity(1026) in blocking elevated production of sebum by hyperactive sebaceous glands and blockage of the follicle(1022). According to Telemark Hospital, the acid may also be beneficiary for increased the clinical pregnancy rate when used conjunction with vitro fertilisation (IVF)/intra-cytoplasmic sperm injection (ICSI)(1024) and protective against fetal losses(1025), through its anti antithrombotic property(1025). The synthetic version of salicylic acid has also shown to consisting aspirin's cardioprotective effects through its antithrombotic and anti-inflammatory actions(1027).
3. Immune system
The antioxidant(1028)(1029) and anti inflammatory(1030)(1031) effects of white willow enhance immune system fighting against microbial invasion and guarding our body DNA integrity(1033) against irregular cell growth(1032)(1033) through inhibiting the effect of intermediate enzymes and other mechanisms(1027)
d. Vitamin C
Natural vitamin polypeptide C white willow found in white willow not only is found to consist the weight loss property(See the weight loss vitamin C)[
Vitami C found abundantly in red clover has shown strong evidneces epidemiologically in reducing weight loss for obese population, espexially for obese women with PCOs.
See The weight loss vitamin C for more details
[Vitamin C and other nutrients deficiency not only is associated to the risk of Obesity(807) but also enhances the risk of lipids, inflammation and insulin resistance(808).
According to the research team at Universidad Autónoma de Querétaro, there is an associated link between Obesity and Zinc and vitamins A and C concentration in in women from rural Mexico, in a fasting blood sample analysis (809).
Although genetic susceptibility to obesity is associated with gene polymorphisms affecting biochemical pathways which also impacted by specific foods and nutrients. According to Dr. Johnston CS., vitamin C depletion is associated to positively related to body mass, individuals with adequate vitamin C status oxidize 30% more fat during a moderate exercise bout than individuals with low vitamin C status(810)
Vitamin C, the protective effect against obesity
Endothelial dysfunction has found to be associated to the incidence of obesity(811). The study of 76 healthy subjects (50 men and 26 women aged 21-45 years) obese subject, showed a positive effect of vitamin C and indomethacin in reduced oxidative stress contributed to endothelial dysfunction in human obesity(812).
In the evaluation of the potential inhibitory activity on α-glucosidase and pancreatic lipase by Citrus spp. fruits of Spanish origin, grapefruit, contained higher contents of phytochemicals such as vitamin C, is found to have a great value for nutrition and treatment of diet-related diseases(813).
L-Ascorbic acid in the study, whether would facilitate the anti-obesity effects of chitosan and psyllium husk in vivo, showed addition of vitamin C in diet influenced the reduction in body weight gain and food efficiency ratio, and the increase in total fecal weight and fecal fat excretion in guinea pigs fed a high-fat diet(814)]
but also improves the immune function in fighting against the forming of free radicals(1034) and foreign invasion(1035) but also increases the blood flow to the reproductive organ(1036)(1037)(1038) through reducing oxidant stress, increasing NO bioavailability(1037) of which may reduce risk sexual libido(1038) and enhance the chance of conception(1039)(1040)(1041).
Side effects
1. Risk of anaphylactic reaction to patients with a history of allergy to salicylates(1042).
2. Over dose of white willow may cause digestive disorder such as nausea and stomachache(1044)
3. Do not use the herb(1043)
a. If you are aspirin allergy/sensitivity,
b. If you are taking anticoagulants or "blood thinners," and
c. On children with flu-like symptoms or Reye's syndrome.
Ovarian Cysts And PCOS Elimination
References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndrome and healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(827a) Diet and nutrition in polycystic ovary syndrome (PCOS): pointers for nutritional management by Farshchi H, Rane A, Love A, Kennedy RL(PubMed)
(828) The optimal diet for women with polycystic ovary syndrome? by Marsh K, Brand-Miller J.(PubMed)
(1009) In vitro anti-proliferative effects of the willow bark extract STW 33-I by Bonaterra GA1, Kelber O, Weiser D, Metz J, Kinscherf R.(PubMed)
(1010) Willow leaves' extracts contain anti-tumor agents effective against three cell types by El-Shemy HA1, Aboul-Enein AM, Aboul-Enein KM, Fujita K.(PubMed)
(1011) Mechanisms involved in the anti-inflammatory effect of a standardized willow bark extract by Khayyal MT1, El-Ghazaly MA, Abdallah DM, Okpanyi SN, Kelber O, Weiser D.(PubMed)
(1012) Amelioration of collagen-induced arthritis by Salix nigra bark extract via suppression of pro-inflammatory cytokines and oxidative stress by Sharma S1, Sahu D, Das HR, Sharma D.(PubMed)
(1013) Antimicrobial effects of Finnish plant extracts containing flavonoids and other phenolic compounds by Rauha JP1, Remes S, Heinonen M, Hopia A, Kähkönen M, Kujala T, Pihlaja K, Vuorela H, Vuorela P.(PubMed)
(1014) The study of interactions between active compounds of coffee and willow (Salix sp.) bark by water extract. Durak A1, Gawlik-Dziki U1.(PubMed)
(1015) Willow bark extract increases antioxidant enzymes and reduces oxidative stress through activation of Nrf2 in vascular endothelial cells and Caenorhabditis elegans by Ishikado A1, Sono Y, Matsumoto M, Robida-Stubbs S, Okuno A, Goto M, King GL, Blackwell TK, Makino T.(PubMed)
(1016) What Your Doctor May Not Tell You About(TM) Getting Pregnant: Boost Your ... By Raymond Chang, Elena Oumano
(1017) antiestrigenic effectsof bee pollen from Cystus incanus and Salix alba as evaluated by the yeast estrogen screen and the micronucleus assay in human lymphocytes by Pinto B1, Caciagli F, Riccio E, Reali D, Sarić A, Balog T, Likić S, Scarpato R.(PubMed)
(1018) Adaptive hypersensitivity to estrogen: mechanisms and clinical relevance to aromatase inhibitor therapy in breast cancer treatment by Santen RJ1, Song RX, Zhang Z, Kumar R, Jeng MH, Masamura S, Lawrence J Jr, MacMahon LP, Yue W, Berstein L.(PubMed)
(1019) Transcriptional implications of intragenic DNA methylation in the oestrogen receptor alpha gene in breast cancer cells and tissues by Shenker NS1, Flower KJ2, Wilhelm-Benartzi CS3, Dai W4,5, Bell E6, Gore E7, El Bahrawy M8, Weaver G9, Brown R10, Flanagan JM11.(PubMed)
(1020) Sex hormone imbalances and adipose tissue dysfunction impacting on metabolic syndrome; a paradigm for the discovery of novel adipokines by Zhang H, Sairam MR.(PubMed)
(1021) Metabolic Balance for Maximum Health 6/06 June 6, 2006 - - + Juvenon Health Journal Vol. 5 No. 6, June 2006
(1022) [Use of organic acids in acne and skin discolorations therapy].[Article in Polish]by Kapuścińska A1, Nowak I1.(PubMed)
(1023) Rapid treatment of mild acne with a novel skin care system containing 1% salicylic acid, 10% buffered glycolic acid, and botanical ingredients by Bhatia AC, Jimenez F.(PubMed)
(1024) Do acetyl salicylic acid and terbutaline in combination increase the probability of a clinical pregnancy in patients undergoing IVF/ICSI by Hanevik HI1, Friberg M, Bergh A, Haraldsen C, Kahn JA.(PubMed)
(1025) Efficacy of three different antithrombotic regimens on pregnancy outcome in pregnant women affected by recurrent pregnancy loss by Giancotti A1, La Torre R, Spagnuolo A, D'Ambrosio V, Cerekja A, Piazze J, Chistolini A.(PubMed)
(1026) Clinical evidence on the efficacy and safety of an antioxidant optimized 1.5% salicylic acid (SA) cream in the treatment of facial acne: an open, baseline-controlled clinical study by Zheng Y1, Wan M, Chen H, Ye C, Zhao Y, Yi J, Xia Y, Lai W.(PubMed)
(1027) Molecular targets of aspirin and cancer prevention by Alfonso L1, Ai G2, Spitale RC3, Bhat GJ2.(PubMed)
(1028) Effects of salicylic acid and putrescine on storability, quality attributes and antioxidant activity of plum cv. 'Santa Rosa' by Davarynejad GH1, Zarei M1, Nasrabadi ME1, Ardakani E1.(PubMed)
(1029) Salicylic acid promotes seed germination under high salinity by modulating antioxidant activity in Arabidopsis by Lee S1, Kim SG, Park CM.(PubMed)
(1030) An in vivo study examining the antiinflammatory effects of chamomile, meadowsweet, and willow bark in a novel functional beverage by Drummond EM1, Harbourne N, Marete E, Jacquier JC, O'Riordan D, Gibney ER.(PubMed)
(1031) Inhibition of proinflammatory biomarkers in THP1 macrophages by polyphenols derived from chamomile, meadowsweet and willow bark by Drummond EM1, Harbourne N, Marete E, Martyn D, Jacquier J, O'Riordan D, Gibney ER.(PubMed)
(1032) Willow bark extract (BNO1455) and its fractions suppress growth and induce apoptosis in human colon and lung cancer cells by Hostanska K1, Jürgenliemk G, Abel G, Nahrstedt A, Saller R.(PubMed)
(1033) In vitro anti-proliferative effects of the willow bark extract STW 33-I. by Bonaterra GA1, Kelber O, Weiser D, Metz J, Kinscherf R.(PubMed)
(1034) Comprehensive study on vitamin C equivalent antioxidant capacity (VCEAC) of various polyphenolics in scavenging a free radical and its structural relationship by Kim DO1, Lee CY.(PubMed)
(1035) Structure, mechanism and regulation of an artificial microbial ecosystem for vitamin C production by Zou W1, Liu L, Chen J.(PubMed)
(1036) Melatonin and vitamin C increase umbilical blood flow via nitric oxide-dependent mechanisms by Thakor AS1, Herrera EA, Serón-Ferré M, Giussani DA.(PubMed)
(1037) Tetrahydrobiopterin, L-arginine and vitamin C act synergistically to decrease oxidant stress and increase nitric oxide that increases blood flow recovery after hindlimb ischemia in the rat by Yan J1, Tie G, Messina LM.(PubMed)
(1038) Protective role of ascorbic acid to enhance reproductive performance of male rabbits treated with stannous chloride by Yousef MI1.(PubMed)
(1039) Efficacy of vitamin C and ethanolic extract of Sesamum indicum in promoting fertility in male Wistar rats by Ashamu E1, Salawu E, Oyewo O, Alhassan A, Alamu O, Adegoke A.(PubMed)
(1040) Vitamin C--the primate fertility factor? by Millar J1.(PubMed)
(1041) Promoting extracellular matrix remodeling via ascorbic acid enhances the survival of primary ovarian follicles encapsulated in alginate hydrogels by Tagler D1, Makanji Y, Tu T, Bernabé BP, Lee R, Zhu J, Kniazeva E, Hornick JE, Woodruff TK, Shea LD.(PubMed)
The best weightloss and healthy recipe: Lettuce egg toss
Posted By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Recipes contributed by Company's Coming Salads by Jean Pare
A superb addition way to serve lettuce. If ef are in good supply add other one ot two
Lettuce, solid medium head 1/2
Green onion, sliced (optional) 3-5
Hard broiled egg, cut up 2
salad dressing ( or mayonnaise) to coat
Tear or cut lettuce into bite size pieces. Add onion and egg. Add sald dressing. Toss and serve. Serve 6-8.
Egg mushroom toss
Add 1/2 to 1 cup (125 to 250 ml) sliced fresh mushroom before tossing
Lettuce cheese salad
Egg may be omitted if preferred. Add 1/2 to 1 cup (125 -250 ml) grated or diced Chedder cheese. Colorful, health, good!
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Recipes contributed by Company's Coming Salads by Jean Pare
A superb addition way to serve lettuce. If ef are in good supply add other one ot two
Lettuce, solid medium head 1/2
Green onion, sliced (optional) 3-5
Hard broiled egg, cut up 2
salad dressing ( or mayonnaise) to coat
Tear or cut lettuce into bite size pieces. Add onion and egg. Add sald dressing. Toss and serve. Serve 6-8.
Egg mushroom toss
Add 1/2 to 1 cup (125 to 250 ml) sliced fresh mushroom before tossing
Lettuce cheese salad
Egg may be omitted if preferred. Add 1/2 to 1 cup (125 -250 ml) grated or diced Chedder cheese. Colorful, health, good!
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
Saturday 2 May 2015
The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome: The Fertility Herb Licorice
By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovasular disease(8)(13), acne(10)(14), endometrial cance(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasing altered glucose tolerance(20), CVD and hypertension(21).
The prevention and management In Herbal Medicine
Polycystic ovary syndrome (PCOS) is unpreventable in Western medicine. Early diagnosis and treatment may reduce risk of its complications, including infertility, metabolic syndrome, obesity, diabetes, cardiovascular diseases, stroke, etc.
Reduce fat intake less than 30% of total calories with a low proportion of saturated fat and high in fiber from predominantly low-glycaemic-index-carbohydrate foods for patients with PCOs(827a). Calorie intake should be distributed between several meals per day with restricted intake of snacks and drinks(828).
The Fertility Herb: Licorice
See the common herbs used for treatment of PCO
Ovarian Cysts And PCOS Elimination
References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndrome and healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(827a) Diet and nutrition in polycystic ovary syndrome (PCOS): pointers for nutritional management by Farshchi H, Rane A, Love A, Kennedy RL(PubMed)
(828) The optimal diet for women with polycystic ovary syndrome? by Marsh K, Brand-Miller J.(PubMed)
(983) Antithrombotic effect of Glycyrrhizin, a plant-derived thrombin inhibitor by Mendes-Silva W1, Assafim M, Ruta B, Monteiro RQ, Guimarães JA, Zingali RB.(PubMed)
(984) Hypocholesterolaemic and antioxidant effects of Glycyrrhiza glabra (Linn) in rats by Visavadiya NP1, Narasimhacharya AV.(PubMed)
(985) Antiatherosclerotic effects of licorice extract supplementation on hypercholesterolemic patients: increased resistance of LDL to atherogenic modifications, reduced plasma lipid levels, and decreased systolic blood pressure by Fuhrman B1, Volkova N, Kaplan M, Presser D, Attias J, Hayek T, Aviram M.(PubMed)
(986) [Exploration into rules of combined Chinese and Western medical treatment on immune infertility].[Article in Chinese] by Yao DN1, Chen WY, Xiao Y.(PubMed)
(987) [Treatment of irritable bowel syndrome by Chinese medicine and pharmacy: an analysis of data mining on experiences of experts].[Article in Chinese] by Zhang BH1, Gao R, Li ZH, Li BS, Wang FY, Tang XD.(PubMed)
(988) [Pharmacological study of the anti-inflammatory agent glyderinine].[Article in Russian] by Azimov MM, Zakirov UB, Radzhapova ShD.(PubMed)
(989) Glycyrrhizin protects mice against renal ischemia-reperfusion injury through inhibition of apoptosis and inflammation by downregulating p38 mitogen-activated protein kinase signaling by Ye S1, Zhu Y1, Ming Y1, She X1, Liu H1, Ye Q1.(PubMed)
(990) Protective effect of glycyrrhizin, a direct HMGB1 inhibitor, on focal cerebral ischemia/reperfusion-induced inflammation, oxidative stress, and apoptosis in rats by Gong G1, Xiang L2, Yuan L3, Hu L1, Wu W1, Cai L1, Yin L1, Dong H3.(PubMed)
(991) [Effect of shakuyaku-kanzo-to, shakuyaku, kanzo, paeoniflorin, glycyrrhetinic acid and glycyrrhizin on ovarian function in rats].[Article in Japanese] by Takeuchi T1.(PubMed)
(992) Glycyrrhizin induces apoptosis in prostate cancer cell lines DU-145 and LNCaP by Thirugnanam S1, Xu L, Ramaswamy K, Gnanasekar M.(PubMed)
(993) Glycyrrhetic acid (a metabolic substance and aglycon of glycyrrhizin) induces apoptosis in human hepatoma, promyelotic leukemia and stomach cancer cells by Hibasami H1, Iwase H, Yoshioka K, Takahashi H.(PubMed)
(994) Glycyrrhizin, an active component of licorice roots, reduces morbidity and mortality of mice infected with lethal doses of influenza virus by Utsunomiya T1, Kobayashi M, Pollard RB, Suzuki F.(PubMed)
(995) Glycyrrhizin stimulates growth of Eubacterium sp. strain GLH, a human intestinal anaerobe by Akao T1, Akao T, Kobashi K.(PubMed)
(996) [Involvement of striatal serotonin in fluoxetine effects on adrenocortical function and behaviour].[Article in Russian] by Shishkina GT, Bulygina VV, Iudina AM, Tolstikova TG, Dygalo NN.(PubMed)
(997) Relationships between androgens, serotonin gene expression and innervation in male macaques by Bethea CL1, Coleman K2, Phu K3, Reddy AP3, Phu A3.(PubMed)
(998) Phospholipid transfer protein is expressed in cerebrovascular endothelial cells and involved in high density lipoprotein biogenesis and remodeling at the blood-brain barrier by Chirackal Manavalan AP1, Kober A, Metso J, Lang I, Becker T, Hasslitzer K, Zandl M, Fanaee-Danesh E, Pippal JB, Sachdev V, Kratky D, Stefulj J, Jauhiainen M, Panzenboeck U.(PubMed)
(999) Alterations in phospholipidomic profile in the brain of mouse model of depression induced by chronic unpredictable stress by Faria R1, Santana MM2, Aveleira CA3, Simões C1, Maciel E1, Melo T1, Santinha D1, Oliveira MM4, Peixoto F5, Domingues P1, Cavadas C2, Domingues MR6.(PubMed)
(1000) Effects of soy lecithin phosphatidic acid and phosphatidylserine complex (PAS) on the endocrine and psychological responses to mental stress by Hellhammer J1, Fries E, Buss C, Engert V, Tuch A, Rutenberg D, Hellhammer D.(PubMed)
(1001) Lecithin:cholesterol acyltransferase deficiency protects against cholesterol-induced hepatic endoplasmic reticulum stress in mice by Hager L1, Li L, Pun H, Liu L, Hossain MA, Maguire GF, Naples M, Baker C, Magomedova L, Tam J, Adeli K, Cummins CL, Connelly PW, Ng DS.(PubMed)
(1002) Altered phospholipid metabolism in schizophrenia: a phosphorus 31 nuclear magnetic resonance spectroscopy study by Weber-Fahr W1, Englisch S, Esser A, Tunc-Skarka N, Meyer-Lindenberg A, Ende G, Zink M.(PubMed)
(1003) Licorice-induced hypertension and syndromes of apparent mineralocorticoid excess by Walker BR1, Edwards CR.(PubMed)
(1004) Gan Cao(Chinese(Complementary and Alternative Healing University)
(1005) Licorice-induced hypokalemia by Mumoli N, Cei M.(PubMed)
(1006) Glycyrrhizic acid toxicity caused by consumption of licorice candy cigars by Johns C1.(PubMed)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovasular disease(8)(13), acne(10)(14), endometrial cance(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasing altered glucose tolerance(20), CVD and hypertension(21).
The prevention and management In Herbal Medicine
Polycystic ovary syndrome (PCOS) is unpreventable in Western medicine. Early diagnosis and treatment may reduce risk of its complications, including infertility, metabolic syndrome, obesity, diabetes, cardiovascular diseases, stroke, etc.
Reduce fat intake less than 30% of total calories with a low proportion of saturated fat and high in fiber from predominantly low-glycaemic-index-carbohydrate foods for patients with PCOs(827a). Calorie intake should be distributed between several meals per day with restricted intake of snacks and drinks(828).
The Fertility Herb: Licorice
See the common herbs used for treatment of PCO
[Gan Cao is also known as Licorice root. The sweet and neutral
herb has been used in TCM as anti allergy(856), anti inflammation(855), anti
ulcer(857), anti convulsion(858), oxidative stress(858) and to treat stomach weakness, tired and lack of
strength, palpitation and short of breath, cough with abundance of
phlegm, stomach and solar plexus pain(859), etc., as it tonifies the Spleen,
benefits the Qi, moistens the Lungs, calms cough, deaf or acute pain,
by enhancing all 12 channels(859). Licorice, in a review of 33 studies of herbal medicine for the management of polycystic ovary syndrome
(PCOS), showed a stronge evidences in improved metabolic hormone
profile and improved fertility outcomes and regulation of ovulation and
inhibition of hyperandrogenism in PCOS(860). In model rats
experiment, Ganshao Paste (CGP), also decreased serum levels of
LH, T, and FSH and increased of serum estradiol (E2), and progesterone
(P)(861)(860)(865). According to University
of Natural Resources and Life Sciences Vienna, licorice may have a
potential effect on metabolic syndrome(862) in women with PCOs.]
2. Blow flow
Licorice improves the blood flow in the body by exerting its anti thrombosis(983) and inhibiting the levels of bad cholesterol(984)(985) and triglyceride levels(985) and increasing HDL-cholesterol content(984) in reduced risk of cardiovascular disease(985) and blood stagnation(897) in the abdominal region induced induced infertility(986).
3. Glycyrrhizin
Glycyrrhizin, one of main ingredient from licorice, exhibited anti inflammatory effect pharmacologically in treatment of inflammatory diseases(988)(989)(990), lowered high serum testosterone levels in oligomenorrheic or amenorrheic women, and induced conception in some women(991). As antioxidant, the phytochemical also inhibit irregular cell growth(992)(993) and microbial invasion(994)(995) causes of cancers(992)(993) and infection and inflammation(994)(995) respectively. in adrenocortical function and behavour, it also regulated the levels of cortisol(996), induced by over production of serotonin cause of hormone imbalance(997).
4. Phytoestrogen
2. Blow flow
Licorice improves the blood flow in the body by exerting its anti thrombosis(983) and inhibiting the levels of bad cholesterol(984)(985) and triglyceride levels(985) and increasing HDL-cholesterol content(984) in reduced risk of cardiovascular disease(985) and blood stagnation(897) in the abdominal region induced induced infertility(986).
3. Glycyrrhizin
Glycyrrhizin, one of main ingredient from licorice, exhibited anti inflammatory effect pharmacologically in treatment of inflammatory diseases(988)(989)(990), lowered high serum testosterone levels in oligomenorrheic or amenorrheic women, and induced conception in some women(991). As antioxidant, the phytochemical also inhibit irregular cell growth(992)(993) and microbial invasion(994)(995) causes of cancers(992)(993) and infection and inflammation(994)(995) respectively. in adrenocortical function and behavour, it also regulated the levels of cortisol(996), induced by over production of serotonin cause of hormone imbalance(997).
4. Phytoestrogen
See phytoestrogen in black cohosh
[Phytoestrogen found it balck cohosh showed to occupy the estrogen receptor sites in women body(908), through it antiestrogenic and extrogenic effects(909), to induce hormone balancing may result in improving the chance of ovulation and fertility(910)(911)].
5. Lecithin
Lecithin is a fat like substance called a phospholipid improved lipid transfer, cholesterol efflux, HDL genesis and and remodeling at the blood-brain barrier (BBB)(998). against cells from oxidation surrounding the brain(999), in reducing psychotic symptoms(1002) such as stress(1000)(1001), and depression(1002) .
[Phytoestrogen found it balck cohosh showed to occupy the estrogen receptor sites in women body(908), through it antiestrogenic and extrogenic effects(909), to induce hormone balancing may result in improving the chance of ovulation and fertility(910)(911)].
5. Lecithin
Lecithin is a fat like substance called a phospholipid improved lipid transfer, cholesterol efflux, HDL genesis and and remodeling at the blood-brain barrier (BBB)(998). against cells from oxidation surrounding the brain(999), in reducing psychotic symptoms(1002) such as stress(1000)(1001), and depression(1002) .
Side effects
1. It may raise blood pressure(1003)(1004(1006)
2. Long term usage of large dosage can also cause edema(1004)(1006) and hypokalemia(1004)(1005)(1006).
3. Overdose can be toxic(106), in inducing rhabdomyolysis or myoglobinuria(1006).
4. Etc.
1. It may raise blood pressure(1003)(1004(1006)
2. Long term usage of large dosage can also cause edema(1004)(1006) and hypokalemia(1004)(1005)(1006).
3. Overdose can be toxic(106), in inducing rhabdomyolysis or myoglobinuria(1006).
4. Etc.
Ovarian Cysts And PCOS Elimination
References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndrome and healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(827a) Diet and nutrition in polycystic ovary syndrome (PCOS): pointers for nutritional management by Farshchi H, Rane A, Love A, Kennedy RL(PubMed)
(828) The optimal diet for women with polycystic ovary syndrome? by Marsh K, Brand-Miller J.(PubMed)
(983) Antithrombotic effect of Glycyrrhizin, a plant-derived thrombin inhibitor by Mendes-Silva W1, Assafim M, Ruta B, Monteiro RQ, Guimarães JA, Zingali RB.(PubMed)
(984) Hypocholesterolaemic and antioxidant effects of Glycyrrhiza glabra (Linn) in rats by Visavadiya NP1, Narasimhacharya AV.(PubMed)
(985) Antiatherosclerotic effects of licorice extract supplementation on hypercholesterolemic patients: increased resistance of LDL to atherogenic modifications, reduced plasma lipid levels, and decreased systolic blood pressure by Fuhrman B1, Volkova N, Kaplan M, Presser D, Attias J, Hayek T, Aviram M.(PubMed)
(986) [Exploration into rules of combined Chinese and Western medical treatment on immune infertility].[Article in Chinese] by Yao DN1, Chen WY, Xiao Y.(PubMed)
(987) [Treatment of irritable bowel syndrome by Chinese medicine and pharmacy: an analysis of data mining on experiences of experts].[Article in Chinese] by Zhang BH1, Gao R, Li ZH, Li BS, Wang FY, Tang XD.(PubMed)
(988) [Pharmacological study of the anti-inflammatory agent glyderinine].[Article in Russian] by Azimov MM, Zakirov UB, Radzhapova ShD.(PubMed)
(989) Glycyrrhizin protects mice against renal ischemia-reperfusion injury through inhibition of apoptosis and inflammation by downregulating p38 mitogen-activated protein kinase signaling by Ye S1, Zhu Y1, Ming Y1, She X1, Liu H1, Ye Q1.(PubMed)
(990) Protective effect of glycyrrhizin, a direct HMGB1 inhibitor, on focal cerebral ischemia/reperfusion-induced inflammation, oxidative stress, and apoptosis in rats by Gong G1, Xiang L2, Yuan L3, Hu L1, Wu W1, Cai L1, Yin L1, Dong H3.(PubMed)
(991) [Effect of shakuyaku-kanzo-to, shakuyaku, kanzo, paeoniflorin, glycyrrhetinic acid and glycyrrhizin on ovarian function in rats].[Article in Japanese] by Takeuchi T1.(PubMed)
(992) Glycyrrhizin induces apoptosis in prostate cancer cell lines DU-145 and LNCaP by Thirugnanam S1, Xu L, Ramaswamy K, Gnanasekar M.(PubMed)
(993) Glycyrrhetic acid (a metabolic substance and aglycon of glycyrrhizin) induces apoptosis in human hepatoma, promyelotic leukemia and stomach cancer cells by Hibasami H1, Iwase H, Yoshioka K, Takahashi H.(PubMed)
(994) Glycyrrhizin, an active component of licorice roots, reduces morbidity and mortality of mice infected with lethal doses of influenza virus by Utsunomiya T1, Kobayashi M, Pollard RB, Suzuki F.(PubMed)
(995) Glycyrrhizin stimulates growth of Eubacterium sp. strain GLH, a human intestinal anaerobe by Akao T1, Akao T, Kobashi K.(PubMed)
(996) [Involvement of striatal serotonin in fluoxetine effects on adrenocortical function and behaviour].[Article in Russian] by Shishkina GT, Bulygina VV, Iudina AM, Tolstikova TG, Dygalo NN.(PubMed)
(997) Relationships between androgens, serotonin gene expression and innervation in male macaques by Bethea CL1, Coleman K2, Phu K3, Reddy AP3, Phu A3.(PubMed)
(998) Phospholipid transfer protein is expressed in cerebrovascular endothelial cells and involved in high density lipoprotein biogenesis and remodeling at the blood-brain barrier by Chirackal Manavalan AP1, Kober A, Metso J, Lang I, Becker T, Hasslitzer K, Zandl M, Fanaee-Danesh E, Pippal JB, Sachdev V, Kratky D, Stefulj J, Jauhiainen M, Panzenboeck U.(PubMed)
(999) Alterations in phospholipidomic profile in the brain of mouse model of depression induced by chronic unpredictable stress by Faria R1, Santana MM2, Aveleira CA3, Simões C1, Maciel E1, Melo T1, Santinha D1, Oliveira MM4, Peixoto F5, Domingues P1, Cavadas C2, Domingues MR6.(PubMed)
(1000) Effects of soy lecithin phosphatidic acid and phosphatidylserine complex (PAS) on the endocrine and psychological responses to mental stress by Hellhammer J1, Fries E, Buss C, Engert V, Tuch A, Rutenberg D, Hellhammer D.(PubMed)
(1001) Lecithin:cholesterol acyltransferase deficiency protects against cholesterol-induced hepatic endoplasmic reticulum stress in mice by Hager L1, Li L, Pun H, Liu L, Hossain MA, Maguire GF, Naples M, Baker C, Magomedova L, Tam J, Adeli K, Cummins CL, Connelly PW, Ng DS.(PubMed)
(1002) Altered phospholipid metabolism in schizophrenia: a phosphorus 31 nuclear magnetic resonance spectroscopy study by Weber-Fahr W1, Englisch S, Esser A, Tunc-Skarka N, Meyer-Lindenberg A, Ende G, Zink M.(PubMed)
(1003) Licorice-induced hypertension and syndromes of apparent mineralocorticoid excess by Walker BR1, Edwards CR.(PubMed)
(1004) Gan Cao(Chinese(Complementary and Alternative Healing University)
(1005) Licorice-induced hypokalemia by Mumoli N, Cei M.(PubMed)
(1006) Glycyrrhizic acid toxicity caused by consumption of licorice candy cigars by Johns C1.(PubMed)
The best and healthy recipe: Cottage Green
Posted By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Recipes contributed by Company's Coming Salads by Jean Pare
Quick and easy. Nice combination
Cottage cheese 2 cups (500ml)
Shredded lecture, lightly packed 2 cups (500ml)
Crushed pineapple, drained 14 oz. (398 ml)
Salad dressing ( or mayonnaise) 2 tbsp. (30ml)
Combine cottage cheese lettuce and well drained pineapple in a bowl. Add salad dressing. Toss to mix well. Spoon into serving bowl. Serve 4.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Recipes contributed by Company's Coming Salads by Jean Pare
Quick and easy. Nice combination
Cottage cheese 2 cups (500ml)
Shredded lecture, lightly packed 2 cups (500ml)
Crushed pineapple, drained 14 oz. (398 ml)
Salad dressing ( or mayonnaise) 2 tbsp. (30ml)
Combine cottage cheese lettuce and well drained pineapple in a bowl. Add salad dressing. Toss to mix well. Spoon into serving bowl. Serve 4.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
Friday 1 May 2015
The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome: The Fertility Herb Red Clover
By Kyle J. Norton Health article writer and researcher; Over 10.000
articles and research papers have been written and published on line,
including world wide health, ezine articles, article base, healthblogs,
selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovasular disease(8)(13), acne(10)(14), endometrial cance(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasing altered glucose tolerance(20), CVD and hypertension(21).
The prevention and management In Herbal Medicine
Polycystic ovary syndrome (PCOS) is unpreventable in Western medicine. Early diagnosis and treatment may reduce risk of its complications, including infertility, metabolic syndrome, obesity, diabetes, cardiovascular diseases, stroke, etc.
Reduce fat intake less than 30% of total calories with a low proportion of saturated fat and high in fiber from predominantly low-glycaemic-index-carbohydrate foods for patients with PCOs(827a). Calorie intake should be distributed between several meals per day with restricted intake of snacks and drinks(828).
The Fertility Herb: Red Clover
Red clover is an herbaceous, perennial plant, native to Europe, western Asia and northwest Africa, used traditional in treating whooping cough(945), respiratory problems, and skin inflammations(945). menopause symptoms(945)(946)(947) and inflammatory diseases such as atherosclerosis and cardiovascular disease(944) by purifying the blood and clearing mucus from the lungs(948).
1. Isoflavones
Red clover contains isoflavonoid, one type of phytoestrogen used in regulating the levels of estrogen in the body by occupying the estrogen receptor site(949)(950)(951), through its estrogenic(951) and anti estrogenic(952) effects in hormonal balancing for a better chance for fertility(953).
2. Neuroprotective effects
Formononetin (FMNT), an isoflavone found in red clover may be next potential candidate used for neurodegenerative disorders(958)(959) in central nervous system as it significantly attenuated the cell loss induced by induced by N-methyl-D-asparate (NMDA) in primary-cultured cortical neurons, according to the study by Fourth Military Medical University, Xi'an(954). On central nervous system, the herb also was found effective in improve anxiety(955)(856), profuse sweating, insomnia, memory loss, decreased sexual drives(956), depression(957), etc.
3. Metabolic syndrome(967)
Women with PCOs are associated to increased risk metabolic syndrome such as metabolic syndrome risk factors high blood pressure, obesity, high cholesterol, and insulin resistance. Intake of red clover has shown effectively in reduced total serum cholesterol and low-density lipoprotein (LDL) cholesterol levels, triglyceride levels, and increased high-density lipoprotein (HDL) cholesterol(960)(961), lowered cardiovascular risk(962)(963), improved obesity(964) and insulin resistance(965)(966).
4. The weight loss vitamin C
Vitami C found abundantly in red clover has shown strong evidneces epidemiologically in reducing weight loss for obese population, espexially for obese women with PCOs.
See The weight loss vitamin C for more details
[Vitamin C and other nutrients deficiency not only is associated to the risk of Obesity(807) but also enhances the risk of lipids, inflammation and insulin resistance(808).
According to the research team at Universidad Autónoma de Querétaro, there is an associated link between Obesity and Zinc and vitamins A and C concentration in in women from rural Mexico, in a fasting blood sample analysis (809).
Although genetic susceptibility to obesity is associated with gene polymorphisms affecting biochemical pathways which also impacted by specific foods and nutrients. According to Dr. Johnston CS., vitamin C depletion is associated to positively related to body mass, individuals with adequate vitamin C status oxidize 30% more fat during a moderate exercise bout than individuals with low vitamin C status(810)
Vitamin C, the protective effect against obesity
Endothelial dysfunction has found to be associated to the incidence of obesity(811). The study of 76 healthy subjects (50 men and 26 women aged 21-45 years) obese subject, showed a positive effect of vitamin C and indomethacin in reduced oxidative stress contributed to endothelial dysfunction in human obesity(812).
In the evaluation of the potential inhibitory activity on α-glucosidase and pancreatic lipase by Citrus spp. fruits of Spanish origin, grapefruit, contained higher contents of phytochemicals such as vitamin C, is found to have a great value for nutrition and treatment of diet-related diseases(813).
L-Ascorbic acid in the study, whether would facilitate the anti-obesity effects of chitosan and psyllium husk in vivo, showed addition of vitamin C in diet influenced the reduction in body weight gain and food efficiency ratio, and the increase in total fecal weight and fecal fat excretion in guinea pigs fed a high-fat diet(814)]
5. Immunity
Epidemiological studies suggested that red clover processes tenacious anti oxidant(968)(969) and anti inflmmatory(970)(971) effects in fighting against bacterial and viral infection(972)(973) and inflammation(974), free radical(975)(976) causes of irregular cell growth(970)(977) and protecting DNA integrity(979).
Side effects
1. There are no side effects from red clover, but people takes the herb for the first time may experience headache, nausea, and rash(980).
2. Do not use red clover during pregnancy as the herb may increase the risk for vaginal prolapse before the term(981)
3. Risk of bleeding due to its anticoagulant effects(982).
Ovarian Cysts And PCOS Elimination
References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndrome and healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(827a) Diet and nutrition in polycystic ovary syndrome (PCOS): pointers for nutritional management by Farshchi H, Rane A, Love A, Kennedy RL(PubMed)
(828) The optimal diet for women with polycystic ovary syndrome? by Marsh K, Brand-Miller J.(PubMed)
(944) Red clover extract: a source for substances that activate peroxisome proliferator-activated receptor alpha and ameliorate the cytokine secretion profile of lipopolysaccharide-stimulated macrophages by Mueller M1, Hobiger S, Jungbauer A.(PubMed)
(945) The University of Maryland medical center
(946) Effectiveness of red clover in alleviating menopausal symptoms: a 12-week randomized, controlled trial by Shakeri F1, Taavoni S, Goushegir A, Haghani H.(PubMed)
(947) Black cohosh (Cimicifuga spp.) for menopausal symptoms by Leach MJ1, Moore V.(PubMed)
(948) Trifolium pratensen, Phytochemicals by Martina Trossello
(949) [Estrogen-effective isoflavones in Trifolium pratense (red clover). Distribution in superterranean parts of plants and occurrence as "bound" isoflavones].[Article in German]by Schultz G.(PubMed)
(950) Effect of soy isoflavones on endometriosis: interaction with estrogen receptor 2 gene polymorphism. by Tsuchiya M1, Miura T, Hanaoka T, Iwasaki M, Sasaki H, Tanaka T, Nakao H, Katoh T, Ikenoue T, Kabuto M, Tsugane S.(PubMed)
(951) Isoflavones: estrogenic activity, biological effect and bioavailability by Vitale DC1, Piazza C, Melilli B, Drago F, Salomone S.(PubMed)
(952) Phytochemistry and biological properties of glabridin by Simmler C1, Pauli GF, Chen SN.(PubMed)
(953) Recovery of normal fertility after grazing on oestrogenic red clover by Morley FH, Axelsen A, Bennett D.(PubMed)
(954) Neuroprotective effects of formononetin against NMDA-induced apoptosis in cortical neurons by Tian Z1, Liu SB, Wang YC, Li XQ, Zheng LH, Zhao MG.(PubMed)
(955) Improvement of postmenopausal depressive and anxiety symptoms after treatment with isoflavones derived from red clover extracts by Lipovac M1, Chedraui P, Gruenhut C, Gocan A, Stammler M, Imhof M.(PubMed)
(956) A review of non-hormonal options for the relief of menopausal symptoms by Albertazzi P1.(PubMed)
(957) [Feminorm good night to treat the menopause].[Article in Bulgarian] by Malinova M.(PubMed)
(958) The isoflavones mixture from Trifolium pratense L. protects HCN 1-A neurons from oxidative stress by Occhiuto F1, Palumbo DR, Samperi S, Zangla G, Pino A, De Pasquale R, Circosta C.(PubMed)
(959) The phytoestrogenic isoflavones from Trifolium pratense L. (Red clover) protects human cortical neurons from glutamate toxicity by Occhiuto F1, Zangla G, Samperi S, Palumbo DR, Pino A, De Pasquale R, Circosta C.(PubMed)
(960) Influence of red clover-derived isoflavones on serum lipid profile in postmenopausal women by Terzic MM1, Dotlic J, Maricic S, Mihailovic T, Tosic-Race B.(PubMed)
(961) Effect of Trifolium pratense-derived isoflavones on the lipid profile of postmenopausal women with increased body mass index by Chedraui P1, San Miguel G, Hidalgo L, Morocho N, Ross S.(PubMed)
(962) Isoflavones from red clover improve systemic arterial compliance but not plasma lipids in menopausal women by Nestel PJ1, Pomeroy S, Kay S, Komesaroff P, Behrsing J, Cameron JD, West L.(PubMed)
(963) Isoflavones reduce arterial stiffness: a placebo-controlled study in men and postmenopausal women by Teede HJ1, McGrath BP, DeSilva L, Cehun M, Fassoulakis A, Nestel PJ.(PubMed)
(964) Dried Pomegranate Potentiates Anti-Osteoporotic and Anti-Obesity Activities of Red Clover Dry Extracts in Ovariectomized Rats by Kang SJ1,2, Choi BR3, Kim SH4, Yi HY5, Park HR6, Kim DC7, Choi SH8, Han CH9, Park SJ10,8, Song CH10,8, Ku SK11,12, Lee YJ13,14.(PubMed)
(965) Effect of oral phytoestrogen on androgenicity and insulin sensitivity in postmenopausal women by Lee CC1, Bloem CJ, Kasa-Vubu JZ, Liang LJ.(PubMed)
(966) Effects of supplementation with purified red clover (Trifolium pratense) isoflavones on plasma lipids and insulin resistance in healthy premenopausal women by Blakesmith SJ1, Lyons-Wall PM, George C, Joannou GE, Petocz P, Samman S.(PubMed)
(967) Phytoestrogens and the metabolic syndrome by Jungbauer A1, Medjakovic S.(PubMed)
(968) Effect of red clover-derived isoflavone supplementation on insulin-like growth factor, lipid and antioxidant status in healthy female volunteers: a pilot study by Campbell MJ1, Woodside JV, Honour JW, Morton MS, Leathem AJ.(PubMed)
(969) Research on antioxidant effects and estrogenic effect of formononetin from Trifolium pratense (red clover) by Mu H1, Bai YH, Wang ST, Zhu ZM, Zhang YW.(PubMed)
(970) Trifolium species-derived substances and extracts--biological activity and prospects for medicinal applicationsby Kolodziejczyk-Czepas J1.(PubMed)
(971) Biochanin-A, an isoflavon, showed anti-proliferative and anti-inflammatory activities through the inhibition of iNOS expression, p38-MAPK and ATF-2 phosphorylation and blocking NFκB nuclear translocation by Kole L1, Giri B, Manna SK, Pal B, Ghosh S.(PubMed)
(972) Trifolium pratense L. as a potential natural antioxidant by Vlaisavljevic S1, Kaurinovic B2, Popovic M3, Djurendic-Brenesel M4, Vasiljevic B5, Cvetkovic D6, Vasiljevic S7.(PubMed)
(973) Antibacterial activity of leaves extracts of Trifolium alexandrinum Linn. against pathogenic bacteria causing tropical diseases by Khan AV1, Ahmed QU, Shukla I, Khan AA.(PubMed)
(974) Anti-HIV, anti-poxvirus, and anti-SARS activity of a nontoxic, acidic plant extract from the Trifollium species Secomet-V/anti-vac suggests that it contains a novel broad-spectrum antiviral by Kotwal GJ1, Kaczmarek JN, Leivers S, Ghebremariam YT, Kulkarni AP, Bauer G, De Beer C, Preiser W, Mohamed AR.(PubMed)
(975) Free radical scavenging actions of three Trifolium species in the protection of blood plasma antioxidant capacity in vitro by Kolodziejczyk-Czepas J1, Nowak P, Moniuszko-Szajwaj B, Kowalska I, Stochmal A.(PubMed)
(976) Biological activity of clovers - free radical scavenging ability and antioxidant action of six Trifolium species by Kolodziejczyk-Czepas J1, Nowak P, Kowalska I, Stochmal A.(PubMed)
(977) Ester and carbamate ester derivatives of Biochanin A: synthesis and in vitro evaluation of estrogenic and antiproliferative activities by Fokialakis N1, Alexi X, Aligiannis N, Siriani D, Meligova AK, Pratsinis H, Mitakou S, Alexis MN.(PubMed)
(978) Formononetin induces apoptosis in PC-3 prostate cancer cells through enhancing the Bax/Bcl-2 ratios and regulating the p38/Akt pathway by Zhang X1, Bi L, Ye Y, Chen J.(PubMed)
(979) The red clover (Trifolium pratense) isoflavone biochanin A modulates the biotransformation pathways of 7,12-dimethylbenz[a]anthracene by Chan HY1, Wang H, Leung LK.(PubMed)
(980) Red clover(WebMD)
(981) Fertility and growth of nulliparous ewes after feeding red clover silage with high phyto-oestrogen concentrations by Mustonen E1, Taponen S1, Andersson M1, Sukura A2, Katila T1, Taponen J1.(PubMed)
(982) [Oral anticoagulants and medicinal plants. An emerging interaction].[Article in Italian] by Argento A1, Tiraferri E, Marzaloni M.(PubMed)
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovasular disease(8)(13), acne(10)(14), endometrial cance(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasing altered glucose tolerance(20), CVD and hypertension(21).
The prevention and management In Herbal Medicine
Polycystic ovary syndrome (PCOS) is unpreventable in Western medicine. Early diagnosis and treatment may reduce risk of its complications, including infertility, metabolic syndrome, obesity, diabetes, cardiovascular diseases, stroke, etc.
Reduce fat intake less than 30% of total calories with a low proportion of saturated fat and high in fiber from predominantly low-glycaemic-index-carbohydrate foods for patients with PCOs(827a). Calorie intake should be distributed between several meals per day with restricted intake of snacks and drinks(828).
The Fertility Herb: Red Clover
Red clover is an herbaceous, perennial plant, native to Europe, western Asia and northwest Africa, used traditional in treating whooping cough(945), respiratory problems, and skin inflammations(945). menopause symptoms(945)(946)(947) and inflammatory diseases such as atherosclerosis and cardiovascular disease(944) by purifying the blood and clearing mucus from the lungs(948).
1. Isoflavones
Red clover contains isoflavonoid, one type of phytoestrogen used in regulating the levels of estrogen in the body by occupying the estrogen receptor site(949)(950)(951), through its estrogenic(951) and anti estrogenic(952) effects in hormonal balancing for a better chance for fertility(953).
2. Neuroprotective effects
Formononetin (FMNT), an isoflavone found in red clover may be next potential candidate used for neurodegenerative disorders(958)(959) in central nervous system as it significantly attenuated the cell loss induced by induced by N-methyl-D-asparate (NMDA) in primary-cultured cortical neurons, according to the study by Fourth Military Medical University, Xi'an(954). On central nervous system, the herb also was found effective in improve anxiety(955)(856), profuse sweating, insomnia, memory loss, decreased sexual drives(956), depression(957), etc.
3. Metabolic syndrome(967)
Women with PCOs are associated to increased risk metabolic syndrome such as metabolic syndrome risk factors high blood pressure, obesity, high cholesterol, and insulin resistance. Intake of red clover has shown effectively in reduced total serum cholesterol and low-density lipoprotein (LDL) cholesterol levels, triglyceride levels, and increased high-density lipoprotein (HDL) cholesterol(960)(961), lowered cardiovascular risk(962)(963), improved obesity(964) and insulin resistance(965)(966).
4. The weight loss vitamin C
Vitami C found abundantly in red clover has shown strong evidneces epidemiologically in reducing weight loss for obese population, espexially for obese women with PCOs.
See The weight loss vitamin C for more details
[Vitamin C and other nutrients deficiency not only is associated to the risk of Obesity(807) but also enhances the risk of lipids, inflammation and insulin resistance(808).
According to the research team at Universidad Autónoma de Querétaro, there is an associated link between Obesity and Zinc and vitamins A and C concentration in in women from rural Mexico, in a fasting blood sample analysis (809).
Although genetic susceptibility to obesity is associated with gene polymorphisms affecting biochemical pathways which also impacted by specific foods and nutrients. According to Dr. Johnston CS., vitamin C depletion is associated to positively related to body mass, individuals with adequate vitamin C status oxidize 30% more fat during a moderate exercise bout than individuals with low vitamin C status(810)
Vitamin C, the protective effect against obesity
Endothelial dysfunction has found to be associated to the incidence of obesity(811). The study of 76 healthy subjects (50 men and 26 women aged 21-45 years) obese subject, showed a positive effect of vitamin C and indomethacin in reduced oxidative stress contributed to endothelial dysfunction in human obesity(812).
In the evaluation of the potential inhibitory activity on α-glucosidase and pancreatic lipase by Citrus spp. fruits of Spanish origin, grapefruit, contained higher contents of phytochemicals such as vitamin C, is found to have a great value for nutrition and treatment of diet-related diseases(813).
L-Ascorbic acid in the study, whether would facilitate the anti-obesity effects of chitosan and psyllium husk in vivo, showed addition of vitamin C in diet influenced the reduction in body weight gain and food efficiency ratio, and the increase in total fecal weight and fecal fat excretion in guinea pigs fed a high-fat diet(814)]
5. Immunity
Epidemiological studies suggested that red clover processes tenacious anti oxidant(968)(969) and anti inflmmatory(970)(971) effects in fighting against bacterial and viral infection(972)(973) and inflammation(974), free radical(975)(976) causes of irregular cell growth(970)(977) and protecting DNA integrity(979).
Side effects
1. There are no side effects from red clover, but people takes the herb for the first time may experience headache, nausea, and rash(980).
2. Do not use red clover during pregnancy as the herb may increase the risk for vaginal prolapse before the term(981)
3. Risk of bleeding due to its anticoagulant effects(982).
Ovarian Cysts And PCOS Elimination
References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndrome and healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(827a) Diet and nutrition in polycystic ovary syndrome (PCOS): pointers for nutritional management by Farshchi H, Rane A, Love A, Kennedy RL(PubMed)
(828) The optimal diet for women with polycystic ovary syndrome? by Marsh K, Brand-Miller J.(PubMed)
(944) Red clover extract: a source for substances that activate peroxisome proliferator-activated receptor alpha and ameliorate the cytokine secretion profile of lipopolysaccharide-stimulated macrophages by Mueller M1, Hobiger S, Jungbauer A.(PubMed)
(945) The University of Maryland medical center
(946) Effectiveness of red clover in alleviating menopausal symptoms: a 12-week randomized, controlled trial by Shakeri F1, Taavoni S, Goushegir A, Haghani H.(PubMed)
(947) Black cohosh (Cimicifuga spp.) for menopausal symptoms by Leach MJ1, Moore V.(PubMed)
(948) Trifolium pratensen, Phytochemicals by Martina Trossello
(949) [Estrogen-effective isoflavones in Trifolium pratense (red clover). Distribution in superterranean parts of plants and occurrence as "bound" isoflavones].[Article in German]by Schultz G.(PubMed)
(950) Effect of soy isoflavones on endometriosis: interaction with estrogen receptor 2 gene polymorphism. by Tsuchiya M1, Miura T, Hanaoka T, Iwasaki M, Sasaki H, Tanaka T, Nakao H, Katoh T, Ikenoue T, Kabuto M, Tsugane S.(PubMed)
(951) Isoflavones: estrogenic activity, biological effect and bioavailability by Vitale DC1, Piazza C, Melilli B, Drago F, Salomone S.(PubMed)
(952) Phytochemistry and biological properties of glabridin by Simmler C1, Pauli GF, Chen SN.(PubMed)
(953) Recovery of normal fertility after grazing on oestrogenic red clover by Morley FH, Axelsen A, Bennett D.(PubMed)
(954) Neuroprotective effects of formononetin against NMDA-induced apoptosis in cortical neurons by Tian Z1, Liu SB, Wang YC, Li XQ, Zheng LH, Zhao MG.(PubMed)
(955) Improvement of postmenopausal depressive and anxiety symptoms after treatment with isoflavones derived from red clover extracts by Lipovac M1, Chedraui P, Gruenhut C, Gocan A, Stammler M, Imhof M.(PubMed)
(956) A review of non-hormonal options for the relief of menopausal symptoms by Albertazzi P1.(PubMed)
(957) [Feminorm good night to treat the menopause].[Article in Bulgarian] by Malinova M.(PubMed)
(958) The isoflavones mixture from Trifolium pratense L. protects HCN 1-A neurons from oxidative stress by Occhiuto F1, Palumbo DR, Samperi S, Zangla G, Pino A, De Pasquale R, Circosta C.(PubMed)
(959) The phytoestrogenic isoflavones from Trifolium pratense L. (Red clover) protects human cortical neurons from glutamate toxicity by Occhiuto F1, Zangla G, Samperi S, Palumbo DR, Pino A, De Pasquale R, Circosta C.(PubMed)
(960) Influence of red clover-derived isoflavones on serum lipid profile in postmenopausal women by Terzic MM1, Dotlic J, Maricic S, Mihailovic T, Tosic-Race B.(PubMed)
(961) Effect of Trifolium pratense-derived isoflavones on the lipid profile of postmenopausal women with increased body mass index by Chedraui P1, San Miguel G, Hidalgo L, Morocho N, Ross S.(PubMed)
(962) Isoflavones from red clover improve systemic arterial compliance but not plasma lipids in menopausal women by Nestel PJ1, Pomeroy S, Kay S, Komesaroff P, Behrsing J, Cameron JD, West L.(PubMed)
(963) Isoflavones reduce arterial stiffness: a placebo-controlled study in men and postmenopausal women by Teede HJ1, McGrath BP, DeSilva L, Cehun M, Fassoulakis A, Nestel PJ.(PubMed)
(964) Dried Pomegranate Potentiates Anti-Osteoporotic and Anti-Obesity Activities of Red Clover Dry Extracts in Ovariectomized Rats by Kang SJ1,2, Choi BR3, Kim SH4, Yi HY5, Park HR6, Kim DC7, Choi SH8, Han CH9, Park SJ10,8, Song CH10,8, Ku SK11,12, Lee YJ13,14.(PubMed)
(965) Effect of oral phytoestrogen on androgenicity and insulin sensitivity in postmenopausal women by Lee CC1, Bloem CJ, Kasa-Vubu JZ, Liang LJ.(PubMed)
(966) Effects of supplementation with purified red clover (Trifolium pratense) isoflavones on plasma lipids and insulin resistance in healthy premenopausal women by Blakesmith SJ1, Lyons-Wall PM, George C, Joannou GE, Petocz P, Samman S.(PubMed)
(967) Phytoestrogens and the metabolic syndrome by Jungbauer A1, Medjakovic S.(PubMed)
(968) Effect of red clover-derived isoflavone supplementation on insulin-like growth factor, lipid and antioxidant status in healthy female volunteers: a pilot study by Campbell MJ1, Woodside JV, Honour JW, Morton MS, Leathem AJ.(PubMed)
(969) Research on antioxidant effects and estrogenic effect of formononetin from Trifolium pratense (red clover) by Mu H1, Bai YH, Wang ST, Zhu ZM, Zhang YW.(PubMed)
(970) Trifolium species-derived substances and extracts--biological activity and prospects for medicinal applicationsby Kolodziejczyk-Czepas J1.(PubMed)
(971) Biochanin-A, an isoflavon, showed anti-proliferative and anti-inflammatory activities through the inhibition of iNOS expression, p38-MAPK and ATF-2 phosphorylation and blocking NFκB nuclear translocation by Kole L1, Giri B, Manna SK, Pal B, Ghosh S.(PubMed)
(972) Trifolium pratense L. as a potential natural antioxidant by Vlaisavljevic S1, Kaurinovic B2, Popovic M3, Djurendic-Brenesel M4, Vasiljevic B5, Cvetkovic D6, Vasiljevic S7.(PubMed)
(973) Antibacterial activity of leaves extracts of Trifolium alexandrinum Linn. against pathogenic bacteria causing tropical diseases by Khan AV1, Ahmed QU, Shukla I, Khan AA.(PubMed)
(974) Anti-HIV, anti-poxvirus, and anti-SARS activity of a nontoxic, acidic plant extract from the Trifollium species Secomet-V/anti-vac suggests that it contains a novel broad-spectrum antiviral by Kotwal GJ1, Kaczmarek JN, Leivers S, Ghebremariam YT, Kulkarni AP, Bauer G, De Beer C, Preiser W, Mohamed AR.(PubMed)
(975) Free radical scavenging actions of three Trifolium species in the protection of blood plasma antioxidant capacity in vitro by Kolodziejczyk-Czepas J1, Nowak P, Moniuszko-Szajwaj B, Kowalska I, Stochmal A.(PubMed)
(976) Biological activity of clovers - free radical scavenging ability and antioxidant action of six Trifolium species by Kolodziejczyk-Czepas J1, Nowak P, Kowalska I, Stochmal A.(PubMed)
(977) Ester and carbamate ester derivatives of Biochanin A: synthesis and in vitro evaluation of estrogenic and antiproliferative activities by Fokialakis N1, Alexi X, Aligiannis N, Siriani D, Meligova AK, Pratsinis H, Mitakou S, Alexis MN.(PubMed)
(978) Formononetin induces apoptosis in PC-3 prostate cancer cells through enhancing the Bax/Bcl-2 ratios and regulating the p38/Akt pathway by Zhang X1, Bi L, Ye Y, Chen J.(PubMed)
(979) The red clover (Trifolium pratense) isoflavone biochanin A modulates the biotransformation pathways of 7,12-dimethylbenz[a]anthracene by Chan HY1, Wang H, Leung LK.(PubMed)
(980) Red clover(WebMD)
(981) Fertility and growth of nulliparous ewes after feeding red clover silage with high phyto-oestrogen concentrations by Mustonen E1, Taponen S1, Andersson M1, Sukura A2, Katila T1, Taponen J1.(PubMed)
(982) [Oral anticoagulants and medicinal plants. An emerging interaction].[Article in Italian] by Argento A1, Tiraferri E, Marzaloni M.(PubMed)
The Popular Chinese recipe: Mix vegetable herb broth with soft tofu
Posted By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Recipe contributed by 125 Chinese recipes with Bill Jones and Stephen Wong
1 tbsp. butter
1/2 cup diced onion
1 cup diced carrots
5 cups chicken stock or vegetable stock
3 tbsp. white or red miso paste
1 cup frozen peas
1 cup frozen corn kernels
1 lb. soft tofu, cut into 1/2 inch (1 cm) cubes
2tbsp. chopped basil
2 tbsp. chopped parsley, preferably flat-leaf Italian variety
1 tbsp. chopped chives
Season salt and freshly ground black pepper to taste
In a large saucepan or soup pot, melt butter over medium heat. Add onion and carrots; sauté for 1 minute, Add stock and miso and bring to a boil. Add peas and corn kernel; cook for 2 minutes. Skim off any impurities that float to the top.
Gently stir tofu and herbs into the soup and return to a boil. season to taste with seasoned salt and pepper. Removed from heat and serve immediately.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Recipe contributed by 125 Chinese recipes with Bill Jones and Stephen Wong
1 tbsp. butter
1/2 cup diced onion
1 cup diced carrots
5 cups chicken stock or vegetable stock
3 tbsp. white or red miso paste
1 cup frozen peas
1 cup frozen corn kernels
1 lb. soft tofu, cut into 1/2 inch (1 cm) cubes
2tbsp. chopped basil
2 tbsp. chopped parsley, preferably flat-leaf Italian variety
1 tbsp. chopped chives
Season salt and freshly ground black pepper to taste
In a large saucepan or soup pot, melt butter over medium heat. Add onion and carrots; sauté for 1 minute, Add stock and miso and bring to a boil. Add peas and corn kernel; cook for 2 minutes. Skim off any impurities that float to the top.
Gently stir tofu and herbs into the soup and return to a boil. season to taste with seasoned salt and pepper. Removed from heat and serve immediately.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
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