By Kyle J. Norton Health article writer and researcher; Over 10.000
articles and research papers have been written and published on line,
including world wide health, ezine articles, article base, healthblogs,
selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by
Disilgold.com Named 50 of the best health Tweeters Canada - Huffington
Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as
international journal Pharma and Bio science, ISSN 0975-6299.
Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome
is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles
clumping on the ovaries that interferes with the function of the normal
ovaries associated
with a high risk for metabolic disorder(1) as resulting of enlarged
ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovasular disease(8)(13), acne(10)(14), endometrial cance(18)(19),weight
gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1
in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasing altered glucose tolerance(20), CVD and hypertension(21).
The prevention and management In Herbal Medicine
Polycystic
ovary syndrome (PCOS) is unpreventable in Western medicine. Early
diagnosis and treatment may reduce risk of its complications, including
infertility, metabolic syndrome, obesity, diabetes, cardiovascular
diseases, stroke, etc.
Reduce fat intake less than
30% of total calories with a low
proportion of saturated fat and high in fiber from predominantly
low-glycaemic-index-carbohydrate foods for patients with PCOs(827a). Calorie intake
should be distributed between several meals
per day with restricted intake of snacks and drinks(828).
The Fertility Herb: Red Clover
Red clover is an herbaceous,
perennial plant, native to Europe, western Asia and northwest Africa,
used traditional in treating whooping cough(945), respiratory
problems, and skin inflammations(945). menopause symptoms(945)(946)(947)
and inflammatory diseases such as atherosclerosis and cardiovascular
disease(944) by purifying the blood and clearing
mucus from the lungs(948).
1. Isoflavones
Red
clover contains isoflavonoid, one type of phytoestrogen used in
regulating the levels of estrogen in the body by occupying the
estrogen receptor site(949)(950)(951), through its estrogenic(951) and
anti estrogenic(952) effects in hormonal balancing for a better chance
for fertility(953).
2. Neuroprotective effects
Formononetin
(FMNT), an isoflavone found in red clover may be next potential
candidate used for neurodegenerative disorders(958)(959) in central
nervous system as it significantly attenuated the cell loss induced by
induced by N-methyl-D-asparate (NMDA) in primary-cultured cortical
neurons, according to the study by Fourth Military Medical University,
Xi'an(954). On central nervous system, the herb also was found effective
in improve anxiety(955)(856), profuse sweating, insomnia, memory loss,
decreased sexual drives(956), depression(957), etc.
3. Metabolic syndrome(967)
Women with PCOs are associated to increased risk metabolic syndrome such as metabolic
syndrome risk factors high blood pressure, obesity, high cholesterol,
and insulin resistance. Intake of red clover has shown effectively in reduced total serum cholesterol and low-density lipoprotein (LDL) cholesterol levels, triglyceride levels, and increased high-density lipoprotein (HDL) cholesterol(960)(961), lowered cardiovascular risk(962)(963), improved obesity(964) and insulin resistance(965)(966).
4. The weight loss vitamin C
Vitami
C found abundantly in red clover has shown strong evidneces
epidemiologically in reducing weight loss for obese population,
espexially for obese women with PCOs.
See The weight loss vitamin C for more details
[Vitamin C and other nutrients deficiency not only is associated to the
risk of Obesity(807) but also enhances the risk of lipids, inflammation
and insulin resistance(808).
According to the research team at Universidad Autónoma de Querétaro,
there is an associated link between Obesity and Zinc and vitamins A and
C concentration in in women from rural Mexico, in a fasting blood
sample analysis (809).
Although genetic susceptibility to obesity is associated with gene
polymorphisms affecting biochemical pathways which also impacted by
specific foods and nutrients. According to Dr. Johnston CS., vitamin C
depletion is associated to positively related to body mass, individuals
with adequate vitamin C status oxidize 30% more fat during a moderate exercise bout than individuals with low vitamin C status(810)
Vitamin C, the protective effect against obesity
Endothelial dysfunction has found to be associated to the
incidence of obesity(811). The study of 76 healthy subjects (50 men and
26 women aged 21-45 years) obese subject, showed a positive effect of vitamin C and indomethacin in reduced oxidative stress contributed to endothelial dysfunction in human obesity(812).
In the evaluation of the potential inhibitory activity on α-glucosidase
and pancreatic lipase by Citrus spp. fruits of Spanish origin,
grapefruit, contained higher contents of phytochemicals such as vitamin C, is found to have a great value for nutrition and treatment of diet-related diseases(813).
L-Ascorbic acid in the study, whether would facilitate the anti-obesity
effects of chitosan and psyllium husk in vivo, showed addition of
vitamin C in diet influenced the reduction in body weight gain and food
efficiency ratio, and the increase in total fecal weight and fecal fat
excretion in guinea pigs fed a high-fat diet(814)]
5. Immunity
Epidemiological studies suggested that red clover processes tenacious anti oxidant(968)(969)
and anti inflmmatory(970)(971) effects in fighting against bacterial
and viral infection(972)(973) and inflammation(974), free
radical(975)(976) causes of irregular cell growth(970)(977) and
protecting DNA integrity(979).
Side effects
1. There are no side effects
from red clover, but people takes the herb for the first time may
experience headache, nausea, and rash(980).
2. Do not use red clover during pregnancy as the herb may increase the risk for vaginal prolapse before the term(981)
3. Risk of bleeding due to its anticoagulant effects(982).
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndrome and healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome:
a complex condition with psychological, reproductive and metabolic
manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1,
Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A,
Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael
C, Lambrinoudaki I.(PubMed)
(827a) Diet and nutrition in polycystic ovary syndrome (PCOS): pointers for nutritional management by Farshchi H, Rane A, Love A, Kennedy RL(PubMed)
(828) The optimal diet for women with polycystic ovary syndrome? by Marsh K, Brand-Miller J.(PubMed)
(944) Red clover
extract: a source for substances that activate peroxisome
proliferator-activated receptor alpha and ameliorate the cytokine
secretion profile of lipopolysaccharide-stimulated macrophages by Mueller M1, Hobiger S, Jungbauer A.(PubMed)
(945) The University of Maryland medical center
(946) Effectiveness of red clover in alleviating menopausal symptoms: a 12-week randomized, controlled trial by Shakeri F1, Taavoni S, Goushegir A, Haghani H.(PubMed)
(947) Black cohosh (Cimicifuga spp.) for menopausal symptoms by Leach MJ1, Moore V.(PubMed)
(948) Trifolium pratensen, Phytochemicals by Martina Trossello
(949) [Estrogen-effective isoflavones in Trifolium pratense (red clover). Distribution in superterranean parts of plants and occurrence as "bound" isoflavones].[Article in German]by Schultz G.(PubMed)
(950) Effect of soy isoflavones on endometriosis: interaction with estrogen receptor 2 gene polymorphism. by Tsuchiya M1, Miura T, Hanaoka T, Iwasaki M, Sasaki H, Tanaka T, Nakao H, Katoh T, Ikenoue T, Kabuto M, Tsugane S.(PubMed)
(951) Isoflavones: estrogenic activity, biological effect and bioavailability by Vitale DC1, Piazza C, Melilli B, Drago F, Salomone S.(PubMed)
(952) Phytochemistry and biological properties of glabridin by Simmler C1, Pauli GF, Chen SN.(PubMed)
(953) Recovery of normal fertility after grazing on oestrogenic red clover by Morley FH, Axelsen A, Bennett D.(PubMed)
(954) Neuroprotective effects of formononetin against NMDA-induced apoptosis in cortical neurons by Tian Z1, Liu SB, Wang YC, Li XQ, Zheng LH, Zhao MG.(PubMed)
(955) Improvement of postmenopausal depressive and anxiety symptoms after treatment with isoflavones derived from red clover extracts by Lipovac M1, Chedraui P, Gruenhut C, Gocan A, Stammler M, Imhof M.(PubMed)
(956) A review of non-hormonal options for the relief of menopausal symptoms by Albertazzi P1.(PubMed)
(957) [Feminorm good night to treat the menopause].[Article in Bulgarian] by Malinova M.(PubMed)
(958) The isoflavones mixture from Trifolium pratense L. protects HCN 1-A neurons from oxidative stress by Occhiuto F1, Palumbo DR, Samperi S, Zangla G, Pino A, De Pasquale R, Circosta C.(PubMed)
(959) The phytoestrogenic isoflavones from Trifolium pratense L. (Red clover) protects human cortical neurons from glutamate toxicity by Occhiuto F1, Zangla G, Samperi S, Palumbo DR, Pino A, De Pasquale R, Circosta C.(PubMed)
(960) Influence of red clover-derived isoflavones on serum lipid profile in postmenopausal women by Terzic MM1, Dotlic J, Maricic S, Mihailovic T, Tosic-Race B.(PubMed)
(961) Effect of Trifolium pratense-derived isoflavones on the lipid profile of postmenopausal women with increased body mass index by Chedraui P1, San Miguel G, Hidalgo L, Morocho N, Ross S.(PubMed)
(962) Isoflavones from red clover improve systemic arterial compliance but not plasma lipids in menopausal women by Nestel PJ1, Pomeroy S, Kay S, Komesaroff P, Behrsing J, Cameron JD, West L.(PubMed)
(963) Isoflavones reduce arterial stiffness: a placebo-controlled study in men and postmenopausal women by Teede HJ1, McGrath BP, DeSilva L, Cehun M, Fassoulakis A, Nestel PJ.(PubMed)
(964) Dried Pomegranate Potentiates Anti-Osteoporotic and Anti-Obesity Activities of Red Clover Dry Extracts in Ovariectomized Rats by Kang SJ1,2, Choi BR3, Kim SH4, Yi HY5, Park HR6, Kim DC7, Choi SH8, Han CH9, Park SJ10,8, Song CH10,8, Ku SK11,12, Lee YJ13,14.(PubMed)
(965) Effect of oral phytoestrogen on androgenicity and insulin sensitivity in postmenopausal women by Lee CC1, Bloem CJ, Kasa-Vubu JZ, Liang LJ.(PubMed)
(966) Effects of supplementation with purified red clover (Trifolium
pratense) isoflavones on plasma lipids and insulin resistance in healthy
premenopausal women by Blakesmith SJ1, Lyons-Wall PM, George C, Joannou GE, Petocz P, Samman S.(PubMed)
(967) Phytoestrogens and the metabolic syndrome by Jungbauer A1, Medjakovic S.(PubMed)
(968) Effect of red clover-derived isoflavone supplementation on insulin-like growth factor, lipid and antioxidant status in healthy female volunteers: a pilot study by Campbell MJ1, Woodside JV, Honour JW, Morton MS, Leathem AJ.(PubMed)
(969) Research on antioxidant effects and estrogenic effect of formononetin from Trifolium pratense (red clover) by Mu H1, Bai YH, Wang ST, Zhu ZM, Zhang YW.(PubMed)
(970) Trifolium species-derived substances and extracts--biological activity and prospects for medicinal applicationsby Kolodziejczyk-Czepas J1.(PubMed)
(971) Biochanin-A, an isoflavon, showed anti-proliferative and anti-inflammatory
activities through the inhibition of iNOS expression, p38-MAPK and
ATF-2 phosphorylation and blocking NFκB nuclear translocation by Kole L1, Giri B, Manna SK, Pal B, Ghosh S.(PubMed)
(972) Trifolium pratense L. as a potential natural antioxidant by Vlaisavljevic S1, Kaurinovic B2, Popovic M3, Djurendic-Brenesel M4, Vasiljevic B5, Cvetkovic D6, Vasiljevic S7.(PubMed)
(973) Antibacterial activity of leaves extracts of Trifolium alexandrinum Linn. against pathogenic bacteria causing tropical diseases by Khan AV1, Ahmed QU, Shukla I, Khan AA.(PubMed)
(974) Anti-HIV, anti-poxvirus, and anti-SARS activity of a nontoxic, acidic plant extract from the Trifollium species Secomet-V/anti-vac suggests that it contains a novel broad-spectrum antiviral by Kotwal GJ1, Kaczmarek JN, Leivers S, Ghebremariam YT, Kulkarni AP, Bauer G, De Beer C, Preiser W, Mohamed AR.(PubMed)
(975) Free radical scavenging actions of three Trifolium species in the protection of blood plasma antioxidant capacity in vitro by Kolodziejczyk-Czepas J1, Nowak P, Moniuszko-Szajwaj B, Kowalska I, Stochmal A.(PubMed)
(976) Biological activity of clovers - free radical scavenging ability and antioxidant action of six Trifolium species by Kolodziejczyk-Czepas J1, Nowak P, Kowalska I, Stochmal A.(PubMed)
(977) Ester and carbamate ester derivatives of Biochanin A: synthesis and
in vitro evaluation of estrogenic and antiproliferative activities by Fokialakis N1, Alexi X, Aligiannis N, Siriani D, Meligova AK, Pratsinis H, Mitakou S, Alexis MN.(PubMed)
(978) Formononetin induces apoptosis in PC-3 prostate cancer cells through enhancing the Bax/Bcl-2 ratios and regulating the p38/Akt pathway by Zhang X1, Bi L, Ye Y, Chen J.(PubMed)
(979) The red clover (Trifolium pratense) isoflavone biochanin A modulates the biotransformation pathways of 7,12-dimethylbenz[a]anthracene by Chan HY1, Wang H, Leung LK.(PubMed)
(980) Red clover(WebMD)
(981) Fertility and growth of nulliparous ewes after feeding red clover silage with high phyto-oestrogen concentrations by Mustonen E1, Taponen S1, Andersson M1, Sukura A2, Katila T1, Taponen J1.(PubMed)
(982) [Oral anticoagulants and medicinal plants. An emerging interaction].[Article in Italian] by Argento A1, Tiraferri E, Marzaloni M.(PubMed)
Friday, 1 May 2015
The Popular Chinese recipe: Mix vegetable herb broth with soft tofu
Posted By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Recipe contributed by 125 Chinese recipes with Bill Jones and Stephen Wong
1 tbsp. butter
1/2 cup diced onion
1 cup diced carrots
5 cups chicken stock or vegetable stock
3 tbsp. white or red miso paste
1 cup frozen peas
1 cup frozen corn kernels
1 lb. soft tofu, cut into 1/2 inch (1 cm) cubes
2tbsp. chopped basil
2 tbsp. chopped parsley, preferably flat-leaf Italian variety
1 tbsp. chopped chives
Season salt and freshly ground black pepper to taste
In a large saucepan or soup pot, melt butter over medium heat. Add onion and carrots; sauté for 1 minute, Add stock and miso and bring to a boil. Add peas and corn kernel; cook for 2 minutes. Skim off any impurities that float to the top.
Gently stir tofu and herbs into the soup and return to a boil. season to taste with seasoned salt and pepper. Removed from heat and serve immediately.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Recipe contributed by 125 Chinese recipes with Bill Jones and Stephen Wong
1 tbsp. butter
1/2 cup diced onion
1 cup diced carrots
5 cups chicken stock or vegetable stock
3 tbsp. white or red miso paste
1 cup frozen peas
1 cup frozen corn kernels
1 lb. soft tofu, cut into 1/2 inch (1 cm) cubes
2tbsp. chopped basil
2 tbsp. chopped parsley, preferably flat-leaf Italian variety
1 tbsp. chopped chives
Season salt and freshly ground black pepper to taste
In a large saucepan or soup pot, melt butter over medium heat. Add onion and carrots; sauté for 1 minute, Add stock and miso and bring to a boil. Add peas and corn kernel; cook for 2 minutes. Skim off any impurities that float to the top.
Gently stir tofu and herbs into the soup and return to a boil. season to taste with seasoned salt and pepper. Removed from heat and serve immediately.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
Thursday, 30 April 2015
Endometrial Cancer caused by Genes Mutation
Posted By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
The incidence of endometrial cancer among white women are higher in comparison to black. According to the statistic, the risk of endometrial cancer among women is 1 in 7000. Every year, about 40,000 women in US are diagnosed with the disease. Women who carry certain mutation genes, such as BRCA1 or the BRCA2 are associated to increased risk of endometrial cancer.
Endometrium is the inner lining of the mammalian uterus and very susceptible hormone change, particular to menstrual cycle. Endometrial cancer is a late adulthood cancer defined as a condition of which the cells of the endometrial lining of uterus have growth uncontrollable or become cancerous as a result of the alternation of cells DNA. It's the fourth most common cancer among women overall, after breast cancer, lung cancer, and bowel cancer.
The genes mutation
1. BRCA1 or the BRCA2 gene
Women who carry the genes BRCA1 or the BRCA2, according to Familial Breast Cancer Research study are associated to risk of endometrial cancer, specialty for the gene BRCA, but the excessive risk is largely attributable to a history of Tamoxifen use.(1) and in aged group between 45 to 70(2).
2. Mutations in DNA mismatch repair (MMR) genes
Mutations in DNA mismatch repair (MMR) genes affects the DNA repair prowess, elevating endometrial cancer risk, due to the loss of proofreading activity of Polε (3). The University of Oxford study, indicated that mutation of germline exonuclease domain ((EDMs) of POLE and POLD1 are associated to predispose to endometrial cancer (EC) risk(4), Other study showed that defection in either DNA proofreading or MMR may relate to genomic instability and tumourigenesis(5).
3. Phosphatase and tensin homolog (PTEN)
Mation of Mutations of this gene are associated to the development of many types of cancer, specially in altered gene in estrogen-dependent endometrioid endometrial carcinoma tumors(6)
4. K-ras mutations
K-ras gene, protein product plays an essential function in normal tissue signaling. Mutation of KRAS gene is associated to the development of many cancers. According to the study by Haukel and University Hospital, KRAS mutations over amplification and expression were presented in 14.7% of primary lesions with no increase in metastatic lesions but in 18% of metastatic lesions, and high KRAS mRNA levels are associated with aggressive phenotype due to activation of ERK1/2 , (in regulating the malignant potential of cancer cells)(7). According to the study by Kanazawa University, 23% of patients with endometrial cancer carry a mutation in exon 1 of KRAS(7) and 70% of Mutation in codon 12 of the K-ras gene in Serbian patients(8)
5. β-catenin mutation
β-catenin plays an important role in dual function protein by regulating the coordination of cell–cell adhesion and gene transcription, Mutation and over expression are associated to increased risk of endometrial cancer(9). The Sapporo Medical University study insisted that alternation of the beta-catenin gene occurs in atypical hyperplasia or cancer, rather than in simple or complex hyperplasia without atypia(structural abnormality in a cell), during endometrial carcinogenesis(10).
In an immunohistochemically analyzed 80 endometrial samples (30 of normal endometrium, 20 of endometrial hyperplasia, and 30 of endometrial cancer), beta-catenin was observed in 30% of endometrial cancer samples(11).
6. Lynch syndrome
Lynch syndrome is an inherited condition with increased risk of colon and other cancers, caused by a germ line mutation in a mismatch repair gene(12). The risk of Lynch syndrome among endometrial cancer patients is 4.6%(13). In a molecular screening for LS in patients with endometrial cancer ≤ 70 years of age, the risk of LS is 6% of cases(14), Inactivation of the mismatch repair genes MSH2 and MSH6 are associated to hereditary non-polyposis colorectal cancer (HNPCC; Lynch syndrome)(15).
Taking altogether, genetic mutation of certain genes is associated with increased risk of endometrial cancer. Fortunately, certain foods and herbs have found to be effective in suppressing the expression and blocking the preoperative mechanism and pathways. Please note that all articles written by Kyle J. Norton are for information & education only, please consult your Doctor & Related field specialist before applying.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Researched articles - Points of view of Vitamins, Foods and Herbs
http://kylejnorton.blogspot.ca/p/blog-page_24.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
References
(1) The incidence of endometrial cancer in women with BRCA1 and BRCA2 mutations: an international prospective cohort study by Segev Y, Iqbal J, Lubinski J, Gronwald J, Lynch HT, Moller P, Ghadirian P, Rosen B, Tung N, Kim-Sing C, Foulkes WD, Neuhausen SL, Senter L, Singer CF, Karlan B, Ping S, Narod SA; Hereditary Breast Cancer Study Group.(PubMed)
(2) The risk of endometrial cancer in women with BRCA1 and BRCA2 mutations. A prospective study by Beiner ME, Finch A, Rosen B, Lubinski J, Moller P, Ghadirian P, Lynch HT, Friedman E, Sun P, Narod SA; Hereditary Ovarian Cancer Clinical Study Group(PubMed)
(3) A common cancer-associated DNA polymerase {varepsilon} mutation causes an exceptionally strong mutator phenotype, indicating fidelity defects distinct from loss of proofreading by Kane DP, Shcherbakova PV(PubMed)
(4) [Identification and management of HNPCC syndrome (hereditary non polyposis colon cancer), hereditary predisposition to colorectal and endometrial adenocarcinomas].
(7) KRAS gene amplification and overexpression but not mutation associates with aggressive and metastatic endometrial cancer by Birkeland E, Wik E, Mjøs S, Hoivik EA, Trovik J, Werner HM, Kusonmano K, Petersen K, Raeder MB, Holst F, Øyan AM, Kalland KH, Akslen LA, Simon R, Krakstad C, Salvesen HB.(PubMed)
(8) Genetic alterations in SMAD4 and K-ras in Serbian patients with endometrial carcinoma by Nikolic A, Ristanovic M, Perovic V, Trifunovic J, Perovic M, Radojkovic D.(PubMed)
(9) Frequent β-catenin gene mutations in atypical polypoid adenomyoma of the uterus by Takahashi H, Yoshida T, Matsumoto T, Kameda Y, Takano Y, Tazo Y, Inoue H, Saegusa M(PubMed)
(10) Mutation of beta-catenin gene in endometrial cancer but not in associated hyperplasia by Ashihara K, Saito T, Mizumoto H, Nishimura M, Tanaka R, Kudo R.(PubMed)
(11) Nuclear localization of beta-catenin in normal and carcinogenic endometrium by Nei H, Saito T, Yamasaki H, Mizumoto H, Ito E, Kudo R.(PubMed)
(12) Risks of colorectal and other cancers after endometrial cancer for women with Lynch syndrome by Win AK, Lindor NM, Winship I, Tucker KM, Buchanan DD, Young JP, Rosty C, Leggett B, Giles GG, Goldblatt J, Macrae FA, Parry S, Kalady MF, Baron JA, Ahnen DJ, Marchand LL, Gallinger S, Haile RW, Newcomb PA, Hopper JL, Jenkins MA(PubMed)
(13) Prevalence of Lynch syndrome among patients with newly diagnosed endometrial cancers by Egoavil C, Alenda C, Castillejo A, Paya A, Peiro G, Sánchez-Heras AB, Castillejo MI, Rojas E, Barberá VM, Cigüenza S, Lopez JA, Piñero O, Román MJ, Martínez-Escoriza JC, Guarinos C, Perez-Carbonell L, Aranda FI, Soto JL.(PubMed)
(14) Prospective evaluation of molecular screening for Lynch syndrome in patients with endometrial cancer ≤ 70 years by Leenen CH, van Lier MG, van Doorn HC, van Leerdam ME, Kooi SG, de Waard J, Hoedemaeker RF, van den Ouweland AM, Hulspas SM, Dubbink HJ, Kuipers EJ, Wagner A, Dinjens WN, Steyerberg EW.(PubMed)
(15) Structural, molecular and cellular functions of MSH2 and MSH6 during DNA mismatch repair, damage signaling and other noncanonical activities Michael A. Edelbrocka,, Saravanan Kaliyaperumalb, , Kandace J. Williams(Science direct)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
The incidence of endometrial cancer among white women are higher in comparison to black. According to the statistic, the risk of endometrial cancer among women is 1 in 7000. Every year, about 40,000 women in US are diagnosed with the disease. Women who carry certain mutation genes, such as BRCA1 or the BRCA2 are associated to increased risk of endometrial cancer.
Endometrium is the inner lining of the mammalian uterus and very susceptible hormone change, particular to menstrual cycle. Endometrial cancer is a late adulthood cancer defined as a condition of which the cells of the endometrial lining of uterus have growth uncontrollable or become cancerous as a result of the alternation of cells DNA. It's the fourth most common cancer among women overall, after breast cancer, lung cancer, and bowel cancer.
The genes mutation
1. BRCA1 or the BRCA2 gene
Women who carry the genes BRCA1 or the BRCA2, according to Familial Breast Cancer Research study are associated to risk of endometrial cancer, specialty for the gene BRCA, but the excessive risk is largely attributable to a history of Tamoxifen use.(1) and in aged group between 45 to 70(2).
2. Mutations in DNA mismatch repair (MMR) genes
Mutations in DNA mismatch repair (MMR) genes affects the DNA repair prowess, elevating endometrial cancer risk, due to the loss of proofreading activity of Polε (3). The University of Oxford study, indicated that mutation of germline exonuclease domain ((EDMs) of POLE and POLD1 are associated to predispose to endometrial cancer (EC) risk(4), Other study showed that defection in either DNA proofreading or MMR may relate to genomic instability and tumourigenesis(5).
3. Phosphatase and tensin homolog (PTEN)
Mation of Mutations of this gene are associated to the development of many types of cancer, specially in altered gene in estrogen-dependent endometrioid endometrial carcinoma tumors(6)
4. K-ras mutations
K-ras gene, protein product plays an essential function in normal tissue signaling. Mutation of KRAS gene is associated to the development of many cancers. According to the study by Haukel and University Hospital, KRAS mutations over amplification and expression were presented in 14.7% of primary lesions with no increase in metastatic lesions but in 18% of metastatic lesions, and high KRAS mRNA levels are associated with aggressive phenotype due to activation of ERK1/2 , (in regulating the malignant potential of cancer cells)(7). According to the study by Kanazawa University, 23% of patients with endometrial cancer carry a mutation in exon 1 of KRAS(7) and 70% of Mutation in codon 12 of the K-ras gene in Serbian patients(8)
5. β-catenin mutation
β-catenin plays an important role in dual function protein by regulating the coordination of cell–cell adhesion and gene transcription, Mutation and over expression are associated to increased risk of endometrial cancer(9). The Sapporo Medical University study insisted that alternation of the beta-catenin gene occurs in atypical hyperplasia or cancer, rather than in simple or complex hyperplasia without atypia(structural abnormality in a cell), during endometrial carcinogenesis(10).
In an immunohistochemically analyzed 80 endometrial samples (30 of normal endometrium, 20 of endometrial hyperplasia, and 30 of endometrial cancer), beta-catenin was observed in 30% of endometrial cancer samples(11).
6. Lynch syndrome
Lynch syndrome is an inherited condition with increased risk of colon and other cancers, caused by a germ line mutation in a mismatch repair gene(12). The risk of Lynch syndrome among endometrial cancer patients is 4.6%(13). In a molecular screening for LS in patients with endometrial cancer ≤ 70 years of age, the risk of LS is 6% of cases(14), Inactivation of the mismatch repair genes MSH2 and MSH6 are associated to hereditary non-polyposis colorectal cancer (HNPCC; Lynch syndrome)(15).
Taking altogether, genetic mutation of certain genes is associated with increased risk of endometrial cancer. Fortunately, certain foods and herbs have found to be effective in suppressing the expression and blocking the preoperative mechanism and pathways. Please note that all articles written by Kyle J. Norton are for information & education only, please consult your Doctor & Related field specialist before applying.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Researched articles - Points of view of Vitamins, Foods and Herbs
http://kylejnorton.blogspot.ca/p/blog-page_24.html
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References
(1) The incidence of endometrial cancer in women with BRCA1 and BRCA2 mutations: an international prospective cohort study by Segev Y, Iqbal J, Lubinski J, Gronwald J, Lynch HT, Moller P, Ghadirian P, Rosen B, Tung N, Kim-Sing C, Foulkes WD, Neuhausen SL, Senter L, Singer CF, Karlan B, Ping S, Narod SA; Hereditary Breast Cancer Study Group.(PubMed)
(2) The risk of endometrial cancer in women with BRCA1 and BRCA2 mutations. A prospective study by Beiner ME, Finch A, Rosen B, Lubinski J, Moller P, Ghadirian P, Lynch HT, Friedman E, Sun P, Narod SA; Hereditary Ovarian Cancer Clinical Study Group(PubMed)
(3) A common cancer-associated DNA polymerase {varepsilon} mutation causes an exceptionally strong mutator phenotype, indicating fidelity defects distinct from loss of proofreading by Kane DP, Shcherbakova PV(PubMed)
(4) [Identification and management of HNPCC syndrome (hereditary non polyposis colon cancer), hereditary predisposition to colorectal and endometrial adenocarcinomas].
[Article in French by Olschwang S, Bonaïti C, Feingold J, Frébourg T,
Grandjouan S, Lasset C, Laurent-Puig P, Lecuru F, Millat B, Sobol H,
Thomas G, Eisinger F.(PubMed)
(5) DNA polymerase ε and δ exonuclease domain mutations in endometrial cancer by Church
DN, Briggs SE, Palles C, Domingo E, Kearsey SJ, Grimes JM, Gorman M,
Martin L, Howarth KM, Hodgson SV; NSECG Collaborators, Kaur K, Taylor J,
Tomlinson IP(PubMed)
(6) Genetics of Endometrial Cancers by Tsuyoshi Okuda,1,* Akihiko Sekizawa,1 Yuditiya Purwosunu,1, 2 Masaaki Nagatsuka,1 Miki Morioka,1 Masaki Hayashi,1 and Takashi Okai(PubMed)(7) KRAS gene amplification and overexpression but not mutation associates with aggressive and metastatic endometrial cancer by Birkeland E, Wik E, Mjøs S, Hoivik EA, Trovik J, Werner HM, Kusonmano K, Petersen K, Raeder MB, Holst F, Øyan AM, Kalland KH, Akslen LA, Simon R, Krakstad C, Salvesen HB.(PubMed)
(8) Genetic alterations in SMAD4 and K-ras in Serbian patients with endometrial carcinoma by Nikolic A, Ristanovic M, Perovic V, Trifunovic J, Perovic M, Radojkovic D.(PubMed)
(9) Frequent β-catenin gene mutations in atypical polypoid adenomyoma of the uterus by Takahashi H, Yoshida T, Matsumoto T, Kameda Y, Takano Y, Tazo Y, Inoue H, Saegusa M(PubMed)
(10) Mutation of beta-catenin gene in endometrial cancer but not in associated hyperplasia by Ashihara K, Saito T, Mizumoto H, Nishimura M, Tanaka R, Kudo R.(PubMed)
(11) Nuclear localization of beta-catenin in normal and carcinogenic endometrium by Nei H, Saito T, Yamasaki H, Mizumoto H, Ito E, Kudo R.(PubMed)
(12) Risks of colorectal and other cancers after endometrial cancer for women with Lynch syndrome by Win AK, Lindor NM, Winship I, Tucker KM, Buchanan DD, Young JP, Rosty C, Leggett B, Giles GG, Goldblatt J, Macrae FA, Parry S, Kalady MF, Baron JA, Ahnen DJ, Marchand LL, Gallinger S, Haile RW, Newcomb PA, Hopper JL, Jenkins MA(PubMed)
(13) Prevalence of Lynch syndrome among patients with newly diagnosed endometrial cancers by Egoavil C, Alenda C, Castillejo A, Paya A, Peiro G, Sánchez-Heras AB, Castillejo MI, Rojas E, Barberá VM, Cigüenza S, Lopez JA, Piñero O, Román MJ, Martínez-Escoriza JC, Guarinos C, Perez-Carbonell L, Aranda FI, Soto JL.(PubMed)
(14) Prospective evaluation of molecular screening for Lynch syndrome in patients with endometrial cancer ≤ 70 years by Leenen CH, van Lier MG, van Doorn HC, van Leerdam ME, Kooi SG, de Waard J, Hoedemaeker RF, van den Ouweland AM, Hulspas SM, Dubbink HJ, Kuipers EJ, Wagner A, Dinjens WN, Steyerberg EW.(PubMed)
(15) Structural, molecular and cellular functions of MSH2 and MSH6 during DNA mismatch repair, damage signaling and other noncanonical activities Michael A. Edelbrocka,, Saravanan Kaliyaperumalb, , Kandace J. Williams(Science direct)
The Popular Chinese recipe: Curried tomato and Shellfish broth
Posted By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Recipe contributed by 125 Chinese recipes with Bill Jones and Stephen Wong
6 scallops, thinly sliced
8 prawns, peeled and deveined
salt and freshly ground white pepper to taste
2 tsp. vegetable oil
1 small onion, sliced
1tbsp. curry powder, preferably madras
5 cups chicken stock
4 small tomatoes, seed and quartered
12 clams scrubbed
2 cups thinly sliced mustard green or sui choy (Napa cabbage)
salt and pepper to taste
season seafood with salt and pepper; set aside
In a large saucepan or soup pot, heat oil over medium heat for 30 seconds. Add onion and curry powder; sauté for 1 minute. Add chicken stock; bring to a boil. Add tomatoes and cook for 3 minutes. Add clam; cook until they open, about 2 - 5 minutes, depending on size. Skim off any impurities that rise to the top.
Add scallops, prawns and mustard green or cabbage; bring to a boil. Remove from heat. Season to taste with salt and pepper. Cover and allow to steep for 2 minutes. Serve immediately.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Recipe contributed by 125 Chinese recipes with Bill Jones and Stephen Wong
6 scallops, thinly sliced
8 prawns, peeled and deveined
salt and freshly ground white pepper to taste
2 tsp. vegetable oil
1 small onion, sliced
1tbsp. curry powder, preferably madras
5 cups chicken stock
4 small tomatoes, seed and quartered
12 clams scrubbed
2 cups thinly sliced mustard green or sui choy (Napa cabbage)
salt and pepper to taste
season seafood with salt and pepper; set aside
In a large saucepan or soup pot, heat oil over medium heat for 30 seconds. Add onion and curry powder; sauté for 1 minute. Add chicken stock; bring to a boil. Add tomatoes and cook for 3 minutes. Add clam; cook until they open, about 2 - 5 minutes, depending on size. Skim off any impurities that rise to the top.
Add scallops, prawns and mustard green or cabbage; bring to a boil. Remove from heat. Season to taste with salt and pepper. Cover and allow to steep for 2 minutes. Serve immediately.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
Wednesday, 29 April 2015
The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome: The fertility Herb Black Cohosh
By Kyle J. Norton Health article writer and researcher; Over 10.000
articles and research papers have been written and published on line,
including world wide health, ezine articles, article base, healthblogs,
selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovasular disease(8)(13), acne(10)(14), endometrial cance(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasing altered glucose tolerance(20), CVD and hypertension(21).
The prevention and management In Herbal Medicine
Polycystic ovary syndrome (PCOS) is unpreventable in Western medicine. Early diagnosis and treatment may reduce risk of its complications, including infertility, metabolic syndrome, obesity, diabetes, cardiovascular diseases, stroke, etc.
Reduce fat intake less than 30% of total calories with a low proportion of saturated fat and high in fiber from predominantly low-glycaemic-index-carbohydrate foods for patients with PCOs(827a). Calorie intake should be distributed between several meals per day with restricted intake of snacks and drinks(828).
The Fertility Herb: Black cohosh
Black cohosh is a glabrous herbaceous perennial plant, producing large, compound leaves from an underground rhizome and belongs to the family Ranunculaceae used in traditional medicine in treating symptoms of all kinds of gynaecological problems(905), including symptoms of premenstrual tension(907) and menopause(906)
1. Phytoestrogen
Phytoestrogen found it balck cohosh showed to occupy the estrogen receptor sites in women body(908), through it antiestrogenic and extrogenic effects(909), to induce hormone balancing may result in improving the chance of ovulation and fertility(910)(911).
2. Immunity
Black cohosh processes anti inflammatory(913)(914) and anti oxidant(914) effect through enhancing immune system fighting against microbial(915)(916) invasion and irregular cell growth(917)(918) and other inflammatory diseases(913). According to School of Medicine, Wuhan University black cohosh may be beneficiary for patient with patients with coronary heart disease, atherosclerosis, pulmonary heart disease and thrombosis throught its anti inflammatory effects(912).
3. Metabolic Syndrome
In rat model study, black cohosh and its triterpene-saponins showed to reduce high load with fat tissue in the PFD and in the knee joints, body weight, serum leptin and cholesterol and glucose levels caused by metabolic syndrome, according to University Medical Center Göttingen(919). The consumption of black cohost also effectively decreases enhanced pituitary LH secretion, attenuates body weight gain, plasma lipids and intra-abdominal fat (IAF) accumulation, lowers FPI and has no effects on uterine mass(920).
4. Fertility
Use conjunction with clomiphene citrate, black cohosh induced endometrial thickness, serum progesterone and clinical pregnancy rate and cycle outcomes in some infertile couples(921). According to Assiut University, in the differentiation of relatively low pregnancy rates in CC induction cycles of clomiphene citrate in infertile couple, follicular-phase supplements imicifuga racemosa or ethinyl oestradiol needed significantly fewer days for adequate follicular maturation, had a thicker endometrium and higher oestradiol concentration at the time of human chorionic gonadotrophin injection with better outcome of pregnancy rate(922)(923).
5. Condense Tannins
It also contains condense tannin, a type of proanthocyanidin which has been used as nutritional and therapeutic supplements in Europe in promoting the function of flavonoids as an antioxdant(924)(925) to improve Immunity(926)(927) against auto immune response induced infertility(962)(933) and microbial invasion(928)(929), but also maintain DNA integrity about irregular cell growth(930)(931).
6. Nervous Symptoms
Back cohost is said to contain chemical agent to bind the activities to serotonin receptors(939) in decreasing the risk of depression(936), anxiety(934), sleep problem(935) and emotional and physical stress(937)induced risk of infertility(938).
side effects
1. Common side effects include
In high doses of black cohosh may cause abdominal pain, diarrhea, dizziness, headaches, joint pains, nausea, slow heart rate, tremors, visual dimness, vomiting, and weight gain, according to
2. Liver damage
Over dose of back cohosh may cause liver damage(940).
3. Digestive system
Over dose may cause occasional gastrointestinal discomfort, such as diarrhea; nausea and vomiting. sweating; constipation(942).
4. Etc.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndrome and healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(827a) Diet and nutrition in polycystic ovary syndrome (PCOS): pointers for nutritional management by Farshchi H, Rane A, Love A, Kennedy RL(PubMed)
(828) The optimal diet for women with polycystic ovary syndrome? by Marsh K, Brand-Miller J.(PubMed)
(913) Aqueous extracts of Cimicifuga racemosa and phenolcarboxylic constituents inhibit production of proinflammatory cytokines in LPS-stimulated human whole blood by Schmid D1, Woehs F, Svoboda M, Thalhammer T, Chiba P, Moeslinger T.(PubMed)
(914) Inhibition of inducible nitric oxide synthesis by Cimicifuga racemosa (Actaea racemosa, black cohosh) extracts in LPS-stimulated RAW 264.7 macrophages by Schmid D1, Gruber M, Woehs F, Prinz S, Etzlstorfer B, Prucker C, Fuzzati N, Kopp B, Moeslinger T.(PubMed)
(915) Triterpenoid glycoside from Cimicifuga racemosa by Lai GF1, Wang YF, Fan LM, Cao JX, Luo SD.(PubMed)
(916) Extracts of Canadian first nations medicinal plants, used as natural products, inhibit neisseria gonorrhoeae isolates with different antibiotic resistance profiles by Cybulska P1, Thakur SD, Foster BC, Scott IM, Leduc RI, Arnason JT, Dillon JA.(PubMed)
(917) Black cohosh (Cimicifuga racemosa [L.] Nutt.): safety and efficacy for cancer patients by Walji R1, Boon H, Guns E, Oneschuk D, Younus J.(PubMed)
(918) Black cohosh, hot flushes, and breast cancer by Merchant S1, Stebbing J2.(PubMed)
(919) Cimicifuga racemosa and its triterpene-saponins prevent the Metabolic Syndrome and deterioration of cartilage in the knee joint of ovariectomized rats by similar mechanisms by Seidlova-Wuttke D1, Eder N, Stahnke V, Kammann M, Stecher G, Haunschild J, Wessels JT, Wuttke W.(PubMed)
(920) Effects of black cohosh extract on body weight gain, intra-abdominal fat accumulation, plasma lipids and glucose tolerance in ovariectomized Sprague-Dawley rats by Rachoń D1, Vortherms T, Seidlová-Wuttke D, Wuttke W.(PubMed)
(921) Adding phytoestrogens to clomiphene induction in unexplained infertility patients--a randomized trial by Shahin AY1, Ismail AM, Zahran KM, Makhlouf AM.(PubMed)
(922) Supplementation of clomiphene citrate cycles with Cimicifuga racemosa or ethinyl oestradiol--a randomized trial by Shahin AY1, Ismail AM, Shaaban OM.(PubMed)
(923) Adding the phytoestrogen Cimicifugae Racemosae to clomiphene induction cycles with timed intercourse in polycystic ovary syndrome improves cycle outcomes and pregnancy rates - a randomized trial by Shahin AY1, Mohammed SA.(PubMed)
(924) Influence of grape seed proanthocyanidin extract in broiler chickens: effect on chicken coccidiosis and antioxidant status by Wang ML1, Suo X, Gu JH, Zhang WW, Fang Q, Wang X.(PubMed)
(925) The fruit extract of Berberis crataegina DC: exerts potent antioxidant activity and protects DNA integrity by Charehsaz M1, Sipahi H2, Celep E3, Üstündağ A4, Cemiloğlu Ülker Ö5, Duydu Y6, Aydın A7, Yesilada E8.(PubMed)
(926) Grape consumption supports immunity in animals and humans by Percival SS1.(PubMed)
(927) Effect of proanthocyanidin-rich extract from Pinus radiata bark on immune response of specific-pathogen-free White Leghorn chickens by Park IJ1, Cha SY, Kang M, So YS, Go HG, Mun SP, Ryu KS, Jang HK.(PubMed)
(928) Synergistic effect of proanthocyanidin on the bactericidal action of the photolysis of H2O2 ,by Ikai H1, Nakamura K, Kanno T, Shirato M, Meirelles L, Sasaki K, Niwano Y.(PubMed)
(929) Proanthocyanidin-rich extracts from cranberry fruit (Vaccinium macrocarpon Ait.) selectively inhibit the growth of human pathogenic fungi Candida spp. and Cryptococcus neoformans by Patel KD1, Scarano FJ, Kondo M, Hurta RA, Neto CC.(PubMed)
(930) Oligomeric proanthocyanidin complexes (OPC) exert anti-proliferative and pro-apoptotic effects on prostate cancer cells by Neuwirt H1, Arias MC, Puhr M, Hobisch A, Culig Z.(PubMed)
(931) The cytotoxic effects of a novel IH636 grape seed proanthocyanidin extract on cultured human cancer cells by Ye X1, Krohn RL, Liu W, Joshi SS, Kuszynski CA, McGinn TR, Bagchi M, Preuss HG, Stohs SJ, Bagchi D.(PubMed)
(932) Antisperm immunity and infertility by Lu JC1, Huang YF, Lu NQ.(PubMed)
(933) Immune infertility: towards a better understanding of sperm (auto)-immunity. The value of proteomic analysis by Bohring C1, Krause W.(PubMed)
(934) Randomized, double-blind, placebo-controlled trial of Cimicifuga racemosa (black cohosh) in women with anxiety disorder due to menopause by Amsterdam JD1, Yao Y, Mao JJ, Soeller I, Rockwell K, Shults J.(PubMed)
(935) Black cohosh (Cimicifuga racemosa) in tamoxifen-treated breast cancer patients with climacteric complaints - a prospective observational study by Rostock M1, Fischer J, Mumm A, Stammwitz U, Saller R, Bartsch HH.(PubMed)
(936) Black cohosh and fluoxetine in the treatment of postmenopausal symptoms: a prospective, randomized trial by Oktem M1, Eroglu D, Karahan HB, Taskintuna N, Kuscu E, Zeyneloglu HB.(PubMed)
(937) Black Cohosh and Chasteberry: Herbs Valued by Women for Centuries B Y J OSEPH L. M AYO , MD, FACOG
(938) Is infertility really associated with higher levels of mental distress in the female population? Results from the North-Trøndelag Health Study and the Medical Birth Registry of Norway by Biringer E1, Howard LM, Kessler U, Stewart R, Mykletun A.(PubMed)
(939) Metabolism of Nω -methylserotonin, a serotonergic constituent of black cohosh (Cimicifuga racemosa, L. (Nutt.)), by human liver microsomes by Nikolić D1, Li J, van Breemen RB.(PubMed)
(940) Mechanism of hepatotoxicity due to black cohosh (Cimicifuga racemosa): histological, immunohistochemical and electron microscopy analysis of two liver biopsies with clinical correlation by Enbom ET1, Le MD2, Oesterich L3, Rutgers J4, French SW2.(PubMed)
(941)University of Maryland Medical Center((PubMed)
(942) [Efficacy and safety of Black cohosh (Actaea/Cimicifuga racemosa) in the treatment of vasomotor symptoms--review of clinical trials].[Article in Polish] by Kanadys WM1, Leszczyńska-Gorzelak B, Oleszczuk J.(PubMed)
(943) Black cohosh: an alternative therapy for menopause? by Mahady GB1, Fabricant D, Chadwick LR, Dietz B.(PubMed)
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovasular disease(8)(13), acne(10)(14), endometrial cance(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasing altered glucose tolerance(20), CVD and hypertension(21).
The prevention and management In Herbal Medicine
Polycystic ovary syndrome (PCOS) is unpreventable in Western medicine. Early diagnosis and treatment may reduce risk of its complications, including infertility, metabolic syndrome, obesity, diabetes, cardiovascular diseases, stroke, etc.
Reduce fat intake less than 30% of total calories with a low proportion of saturated fat and high in fiber from predominantly low-glycaemic-index-carbohydrate foods for patients with PCOs(827a). Calorie intake should be distributed between several meals per day with restricted intake of snacks and drinks(828).
The Fertility Herb: Black cohosh
Black cohosh is a glabrous herbaceous perennial plant, producing large, compound leaves from an underground rhizome and belongs to the family Ranunculaceae used in traditional medicine in treating symptoms of all kinds of gynaecological problems(905), including symptoms of premenstrual tension(907) and menopause(906)
1. Phytoestrogen
Phytoestrogen found it balck cohosh showed to occupy the estrogen receptor sites in women body(908), through it antiestrogenic and extrogenic effects(909), to induce hormone balancing may result in improving the chance of ovulation and fertility(910)(911).
2. Immunity
Black cohosh processes anti inflammatory(913)(914) and anti oxidant(914) effect through enhancing immune system fighting against microbial(915)(916) invasion and irregular cell growth(917)(918) and other inflammatory diseases(913). According to School of Medicine, Wuhan University black cohosh may be beneficiary for patient with patients with coronary heart disease, atherosclerosis, pulmonary heart disease and thrombosis throught its anti inflammatory effects(912).
3. Metabolic Syndrome
In rat model study, black cohosh and its triterpene-saponins showed to reduce high load with fat tissue in the PFD and in the knee joints, body weight, serum leptin and cholesterol and glucose levels caused by metabolic syndrome, according to University Medical Center Göttingen(919). The consumption of black cohost also effectively decreases enhanced pituitary LH secretion, attenuates body weight gain, plasma lipids and intra-abdominal fat (IAF) accumulation, lowers FPI and has no effects on uterine mass(920).
4. Fertility
Use conjunction with clomiphene citrate, black cohosh induced endometrial thickness, serum progesterone and clinical pregnancy rate and cycle outcomes in some infertile couples(921). According to Assiut University, in the differentiation of relatively low pregnancy rates in CC induction cycles of clomiphene citrate in infertile couple, follicular-phase supplements imicifuga racemosa or ethinyl oestradiol needed significantly fewer days for adequate follicular maturation, had a thicker endometrium and higher oestradiol concentration at the time of human chorionic gonadotrophin injection with better outcome of pregnancy rate(922)(923).
5. Condense Tannins
It also contains condense tannin, a type of proanthocyanidin which has been used as nutritional and therapeutic supplements in Europe in promoting the function of flavonoids as an antioxdant(924)(925) to improve Immunity(926)(927) against auto immune response induced infertility(962)(933) and microbial invasion(928)(929), but also maintain DNA integrity about irregular cell growth(930)(931).
6. Nervous Symptoms
Back cohost is said to contain chemical agent to bind the activities to serotonin receptors(939) in decreasing the risk of depression(936), anxiety(934), sleep problem(935) and emotional and physical stress(937)induced risk of infertility(938).
side effects
1. Common side effects include
In high doses of black cohosh may cause abdominal pain, diarrhea, dizziness, headaches, joint pains, nausea, slow heart rate, tremors, visual dimness, vomiting, and weight gain, according to
2. Liver damage
Over dose of back cohosh may cause liver damage(940).
3. Digestive system
Over dose may cause occasional gastrointestinal discomfort, such as diarrhea; nausea and vomiting. sweating; constipation(942).
4. Etc.
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndrome and healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(827a) Diet and nutrition in polycystic ovary syndrome (PCOS): pointers for nutritional management by Farshchi H, Rane A, Love A, Kennedy RL(PubMed)
(828) The optimal diet for women with polycystic ovary syndrome? by Marsh K, Brand-Miller J.(PubMed)
(905) Predny ML, De Angelis P, Chamberlain JL (2006). Black cohosh (Actaea racemosa): An annotated Bibliography. General Technical Report SRS–97 (Department of Agriculture Forest Service, Southern Research Station). p. 99. Retrieved 2009-08-24.
(906) Black cohosh (Actaea/Cimicifuga racemosa): review of the clinical data for safety and efficacy in menopausal symptoms. by Mahady GB1.(PubMed)
(907) Research highlights from the UIC/NIH Center
for Botanical Dietary Supplements Research for Women’s Health: Black
cohosh from the field to the clinic by Norman R Farnsworth1 and Gail B. Mahady(PubMed)
(908) A phytoestrogen diarylheptanoid mediates estrogen receptor/Akt/glycogen synthase kinase 3β protein-dependent activation of the Wnt/β-catenin signaling pathway. by Bhukhai K1, Suksen K, Bhummaphan N, Janjorn K, Thongon N, Tantikanlayaporn D, Piyachaturawat P, Suksamrarn A, Chairoungdua A.(PubMed)
(909) Isoflavones: chemistry, analysis, functions and effects on health and cancer by Ko KP1.(PubMed)
(910) Adding the phytoestrogen
Cimicifugae Racemosae to clomiphene induction cycles with timed
intercourse in polycystic ovary syndrome improves cycle outcomes and
pregnancy rates - a randomized trial by Shahin AY1, Mohammed SA.(PubMed)
(911) Supplementation of clomiphene citrate cycles with Cimicifuga racemosa or ethinyl oestradiol--a randomized trial by Shahin AY1, Ismail AM, Shaaban OM.(PubMed)
(912) Pharmacological actions of sodium ferulate in cardiovascular system by Wang BH1, Ou-Yang JP.(PubMed)(913) Aqueous extracts of Cimicifuga racemosa and phenolcarboxylic constituents inhibit production of proinflammatory cytokines in LPS-stimulated human whole blood by Schmid D1, Woehs F, Svoboda M, Thalhammer T, Chiba P, Moeslinger T.(PubMed)
(914) Inhibition of inducible nitric oxide synthesis by Cimicifuga racemosa (Actaea racemosa, black cohosh) extracts in LPS-stimulated RAW 264.7 macrophages by Schmid D1, Gruber M, Woehs F, Prinz S, Etzlstorfer B, Prucker C, Fuzzati N, Kopp B, Moeslinger T.(PubMed)
(915) Triterpenoid glycoside from Cimicifuga racemosa by Lai GF1, Wang YF, Fan LM, Cao JX, Luo SD.(PubMed)
(916) Extracts of Canadian first nations medicinal plants, used as natural products, inhibit neisseria gonorrhoeae isolates with different antibiotic resistance profiles by Cybulska P1, Thakur SD, Foster BC, Scott IM, Leduc RI, Arnason JT, Dillon JA.(PubMed)
(917) Black cohosh (Cimicifuga racemosa [L.] Nutt.): safety and efficacy for cancer patients by Walji R1, Boon H, Guns E, Oneschuk D, Younus J.(PubMed)
(918) Black cohosh, hot flushes, and breast cancer by Merchant S1, Stebbing J2.(PubMed)
(919) Cimicifuga racemosa and its triterpene-saponins prevent the Metabolic Syndrome and deterioration of cartilage in the knee joint of ovariectomized rats by similar mechanisms by Seidlova-Wuttke D1, Eder N, Stahnke V, Kammann M, Stecher G, Haunschild J, Wessels JT, Wuttke W.(PubMed)
(920) Effects of black cohosh extract on body weight gain, intra-abdominal fat accumulation, plasma lipids and glucose tolerance in ovariectomized Sprague-Dawley rats by Rachoń D1, Vortherms T, Seidlová-Wuttke D, Wuttke W.(PubMed)
(921) Adding phytoestrogens to clomiphene induction in unexplained infertility patients--a randomized trial by Shahin AY1, Ismail AM, Zahran KM, Makhlouf AM.(PubMed)
(922) Supplementation of clomiphene citrate cycles with Cimicifuga racemosa or ethinyl oestradiol--a randomized trial by Shahin AY1, Ismail AM, Shaaban OM.(PubMed)
(923) Adding the phytoestrogen Cimicifugae Racemosae to clomiphene induction cycles with timed intercourse in polycystic ovary syndrome improves cycle outcomes and pregnancy rates - a randomized trial by Shahin AY1, Mohammed SA.(PubMed)
(924) Influence of grape seed proanthocyanidin extract in broiler chickens: effect on chicken coccidiosis and antioxidant status by Wang ML1, Suo X, Gu JH, Zhang WW, Fang Q, Wang X.(PubMed)
(925) The fruit extract of Berberis crataegina DC: exerts potent antioxidant activity and protects DNA integrity by Charehsaz M1, Sipahi H2, Celep E3, Üstündağ A4, Cemiloğlu Ülker Ö5, Duydu Y6, Aydın A7, Yesilada E8.(PubMed)
(926) Grape consumption supports immunity in animals and humans by Percival SS1.(PubMed)
(927) Effect of proanthocyanidin-rich extract from Pinus radiata bark on immune response of specific-pathogen-free White Leghorn chickens by Park IJ1, Cha SY, Kang M, So YS, Go HG, Mun SP, Ryu KS, Jang HK.(PubMed)
(928) Synergistic effect of proanthocyanidin on the bactericidal action of the photolysis of H2O2 ,by Ikai H1, Nakamura K, Kanno T, Shirato M, Meirelles L, Sasaki K, Niwano Y.(PubMed)
(929) Proanthocyanidin-rich extracts from cranberry fruit (Vaccinium macrocarpon Ait.) selectively inhibit the growth of human pathogenic fungi Candida spp. and Cryptococcus neoformans by Patel KD1, Scarano FJ, Kondo M, Hurta RA, Neto CC.(PubMed)
(930) Oligomeric proanthocyanidin complexes (OPC) exert anti-proliferative and pro-apoptotic effects on prostate cancer cells by Neuwirt H1, Arias MC, Puhr M, Hobisch A, Culig Z.(PubMed)
(931) The cytotoxic effects of a novel IH636 grape seed proanthocyanidin extract on cultured human cancer cells by Ye X1, Krohn RL, Liu W, Joshi SS, Kuszynski CA, McGinn TR, Bagchi M, Preuss HG, Stohs SJ, Bagchi D.(PubMed)
(932) Antisperm immunity and infertility by Lu JC1, Huang YF, Lu NQ.(PubMed)
(933) Immune infertility: towards a better understanding of sperm (auto)-immunity. The value of proteomic analysis by Bohring C1, Krause W.(PubMed)
(934) Randomized, double-blind, placebo-controlled trial of Cimicifuga racemosa (black cohosh) in women with anxiety disorder due to menopause by Amsterdam JD1, Yao Y, Mao JJ, Soeller I, Rockwell K, Shults J.(PubMed)
(935) Black cohosh (Cimicifuga racemosa) in tamoxifen-treated breast cancer patients with climacteric complaints - a prospective observational study by Rostock M1, Fischer J, Mumm A, Stammwitz U, Saller R, Bartsch HH.(PubMed)
(936) Black cohosh and fluoxetine in the treatment of postmenopausal symptoms: a prospective, randomized trial by Oktem M1, Eroglu D, Karahan HB, Taskintuna N, Kuscu E, Zeyneloglu HB.(PubMed)
(937) Black Cohosh and Chasteberry: Herbs Valued by Women for Centuries B Y J OSEPH L. M AYO , MD, FACOG
(938) Is infertility really associated with higher levels of mental distress in the female population? Results from the North-Trøndelag Health Study and the Medical Birth Registry of Norway by Biringer E1, Howard LM, Kessler U, Stewart R, Mykletun A.(PubMed)
(939) Metabolism of Nω -methylserotonin, a serotonergic constituent of black cohosh (Cimicifuga racemosa, L. (Nutt.)), by human liver microsomes by Nikolić D1, Li J, van Breemen RB.(PubMed)
(940) Mechanism of hepatotoxicity due to black cohosh (Cimicifuga racemosa): histological, immunohistochemical and electron microscopy analysis of two liver biopsies with clinical correlation by Enbom ET1, Le MD2, Oesterich L3, Rutgers J4, French SW2.(PubMed)
(941)University of Maryland Medical Center((PubMed)
(942) [Efficacy and safety of Black cohosh (Actaea/Cimicifuga racemosa) in the treatment of vasomotor symptoms--review of clinical trials].[Article in Polish] by Kanadys WM1, Leszczyńska-Gorzelak B, Oleszczuk J.(PubMed)
(943) Black cohosh: an alternative therapy for menopause? by Mahady GB1, Fabricant D, Chadwick LR, Dietz B.(PubMed)
Tuesday, 28 April 2015
The Popular Chinese recipe: Asparagus ginger sesame cream soup
Posted By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Recipe contributed by 125 Chinese recipes with Bill Jones and Stephen Wong
1 tbsp. vegetable oil
1 large onion, coarsely chopped
1 tbsp. minced ginger root
8 0z. asparagus trimmed and chopped
4 cups of chicken stock
1 cup of light(10%) cream
1 tbsp. lemon juice
1 tsp. sesame oil
salt and pepper to taste
2 tbsp. cornstarch dissolved in 4 tbsp. (610ml) water
Minced fresh herbs(chives, basil thyme, rosemary) to taste
1tbsp toasted sesame seeds
In a large saucepan, heat oil over medium-high heat for 30 seconds. Add onion and ginger root; cook until onion softens and begin to change color. Add asparagus and chicken stock; bring mixture to a boil. Reduce heat and simmer for 15 minutes or until the asparagus is cooked.
Removed saucepan from heat and allow to cool. Transfer mixture in batches to a blender or load processor and process until smooth
Pour soup through a strainer; pushing as much puree through the mesh as possible (use the back od a wooden spoon to squeeze out liquid). Return liquid to the saucepan, add cream and warm to a simmer. Add lemon juice, sesame oil, season with salt and pepper. Add dissolved cornstarch; bring soup top a boil, stirring constantly until thickened. garnish with herbs, asparagus cream (direction at below), if desired and toast sesame seeds.
For special finish garnish with asparagus cream. To make asparagus cream. Puree4 spears of cooked asparagus in food processor, then push through a strainer. Measure the puree and mix an equal amount of sour cream. Place a spoon of mixture in the center of each serving and sprinkle with toast sesame seeds.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Recipe contributed by 125 Chinese recipes with Bill Jones and Stephen Wong
1 tbsp. vegetable oil
1 large onion, coarsely chopped
1 tbsp. minced ginger root
8 0z. asparagus trimmed and chopped
4 cups of chicken stock
1 cup of light(10%) cream
1 tbsp. lemon juice
1 tsp. sesame oil
salt and pepper to taste
2 tbsp. cornstarch dissolved in 4 tbsp. (610ml) water
Minced fresh herbs(chives, basil thyme, rosemary) to taste
1tbsp toasted sesame seeds
In a large saucepan, heat oil over medium-high heat for 30 seconds. Add onion and ginger root; cook until onion softens and begin to change color. Add asparagus and chicken stock; bring mixture to a boil. Reduce heat and simmer for 15 minutes or until the asparagus is cooked.
Removed saucepan from heat and allow to cool. Transfer mixture in batches to a blender or load processor and process until smooth
Pour soup through a strainer; pushing as much puree through the mesh as possible (use the back od a wooden spoon to squeeze out liquid). Return liquid to the saucepan, add cream and warm to a simmer. Add lemon juice, sesame oil, season with salt and pepper. Add dissolved cornstarch; bring soup top a boil, stirring constantly until thickened. garnish with herbs, asparagus cream (direction at below), if desired and toast sesame seeds.
For special finish garnish with asparagus cream. To make asparagus cream. Puree4 spears of cooked asparagus in food processor, then push through a strainer. Measure the puree and mix an equal amount of sour cream. Place a spoon of mixture in the center of each serving and sprinkle with toast sesame seeds.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome: The fertility Herb Angelica sinensis
By Kyle J. Norton Health article writer and researcher; Over 10.000
articles and research papers have been written and published on line,
including world wide health, ezine articles, article base, healthblogs,
selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovasular disease(8)(13), acne(10)(14), endometrial cance(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasing altered glucose tolerance(20), CVD and hypertension(21).
The prevention and management In Herbal Medicine
Polycystic ovary syndrome (PCOS) is unpreventable in Western medicine. Early diagnosis and treatment may reduce risk of its complications, including infertility, metabolic syndrome, obesity, diabetes, cardiovascular diseases, stroke, etc.
Reduce fat intake less than 30% of total calories with a low proportion of saturated fat and high in fiber from predominantly low-glycaemic-index-carbohydrate foods for patients with PCOs(827a). Calorie intake should be distributed between several meals per day with restricted intake of snacks and drinks(828).
The Fertility Herb: Angelica sinensis
Dang Qui (Angelica sinensis) is a herb of Genus Angelica from the family Apiaceae, indigenous to China, used as a Queen herb in traditional Chinese medicine as anti inflammatory(889), antispasmodic(890) and vasodilatory agent(891)(890), and to balance the hormones in women for a normal menstrual cycle and menstruation(890), reduce menopausal syndromes(888) and improve digestive system(890) and immunity(890).
1. Reproductive organs tonic
Traditional Chinese medicine views angelica roots as queen herb which has been used to enhance the productive system(892) for treatment of gynecological diseases(897) such as dysmenorrhea, amenorrhoea, menopause and promote menstrual health(892). It is said that angelica roots has the power to restore any deficiency caused by hormone imbalance(894)(895)(896).
2. Blood tonic
A reproductive blood tonic herb(894) not only help to increase blood production(895) to replace blood loss for women after menstruation(893), but also increases the blood flow to abdominal region(890)(891), for induction of healthy conception.
3. Digestive system
Dangqui consists a didestice system protective effects(898) against gastrointestinal damage, but also increases the digestive system function(890) in absorbing essential vitamins and minerals(890), thereby reducing the risks of infertility caused by nutrients deficiency(899).
4. Blood and qi deficiency
Blood(896) and qi(890)deficiency may lead to irregular menstrual cycle, absence of period or painful period(896). Angelica roots increase blood and qi flow(890), resulting in normalizing the function of reproductive organs(892)(897).
5. Kidney tonic
It is said that angelica root also helps to improve kidney function not only in regulating water and fluid through urinary extraction(900), but also improving kidney normal function in regulating the natural menstrual process(900) of the reproductive organs, induced fertility.
6. Immune system
Angelica root containing variety chemicals strengthens the immune system(903) in fighting against infection and inflammation(894)(889), thereby decreasing the risk of yeast infection during menstruation(891) as well as forming of irregular cell growth in the reproductive organs(901)(902)(903).
Side effects
1. It may cause skin inflammation and rashes, if it is taken in high dose(904)
2. Since angelica root causes uterus constraction, the herb should be used on pregnant(904) unless with the approval of her herbalist(904).
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndrome and healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(827a) Diet and nutrition in polycystic ovary syndrome (PCOS): pointers for nutritional management by Farshchi H, Rane A, Love A, Kennedy RL(PubMed)
(828) The optimal diet for women with polycystic ovary syndrome? by Marsh K, Brand-Miller J.(PubMed)
(894) [Experimental study on effects of 18 kinds of Chinese herbal medicine for synthesis of thromboxane A2 and PGI2].[Article in Chinese] by Wang SR1, Guo ZQ, Liao JZ.(PubMed)
(895) Polysaccharide isolated from Angelica sinensis inhibits hepcidin expression in rats with iron deficiency anemia by Liu JY1, Zhang Y, You RX, Zeng F, Guo D, Wang KP.(PubMed)
(896) [Hematopoietic effect of siwu decoction in the mice with blood deficiency induced by compound method of bleeding, starved feeding and exhausting].[Article in Chinese] by Tan W1, Song CS, Tan HL, Liu LL, Ma ZC, Wang YG, Gao Y.(PubMed)
(897) Chemical fingerprinting and quantitative constituent analysis of Siwu decoction categorized formulae by UPLC-QTOF/MS/MS and HPLC-DAD by Shulan Su1, Wenxia Cui12, Wei Zhou1, Jin-ao Duan1*, Erxin Shang1 and Yuping Tang(Chinese medicine)
(898) Study of the gastrointestinal protective effects of polysaccharides from Angelica sinensis in rats.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovasular disease(8)(13), acne(10)(14), endometrial cance(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasing altered glucose tolerance(20), CVD and hypertension(21).
The prevention and management In Herbal Medicine
Polycystic ovary syndrome (PCOS) is unpreventable in Western medicine. Early diagnosis and treatment may reduce risk of its complications, including infertility, metabolic syndrome, obesity, diabetes, cardiovascular diseases, stroke, etc.
Reduce fat intake less than 30% of total calories with a low proportion of saturated fat and high in fiber from predominantly low-glycaemic-index-carbohydrate foods for patients with PCOs(827a). Calorie intake should be distributed between several meals per day with restricted intake of snacks and drinks(828).
The Fertility Herb: Angelica sinensis
Dang Qui (Angelica sinensis) is a herb of Genus Angelica from the family Apiaceae, indigenous to China, used as a Queen herb in traditional Chinese medicine as anti inflammatory(889), antispasmodic(890) and vasodilatory agent(891)(890), and to balance the hormones in women for a normal menstrual cycle and menstruation(890), reduce menopausal syndromes(888) and improve digestive system(890) and immunity(890).
1. Reproductive organs tonic
Traditional Chinese medicine views angelica roots as queen herb which has been used to enhance the productive system(892) for treatment of gynecological diseases(897) such as dysmenorrhea, amenorrhoea, menopause and promote menstrual health(892). It is said that angelica roots has the power to restore any deficiency caused by hormone imbalance(894)(895)(896).
2. Blood tonic
A reproductive blood tonic herb(894) not only help to increase blood production(895) to replace blood loss for women after menstruation(893), but also increases the blood flow to abdominal region(890)(891), for induction of healthy conception.
3. Digestive system
Dangqui consists a didestice system protective effects(898) against gastrointestinal damage, but also increases the digestive system function(890) in absorbing essential vitamins and minerals(890), thereby reducing the risks of infertility caused by nutrients deficiency(899).
4. Blood and qi deficiency
Blood(896) and qi(890)deficiency may lead to irregular menstrual cycle, absence of period or painful period(896). Angelica roots increase blood and qi flow(890), resulting in normalizing the function of reproductive organs(892)(897).
5. Kidney tonic
It is said that angelica root also helps to improve kidney function not only in regulating water and fluid through urinary extraction(900), but also improving kidney normal function in regulating the natural menstrual process(900) of the reproductive organs, induced fertility.
6. Immune system
Angelica root containing variety chemicals strengthens the immune system(903) in fighting against infection and inflammation(894)(889), thereby decreasing the risk of yeast infection during menstruation(891) as well as forming of irregular cell growth in the reproductive organs(901)(902)(903).
Side effects
1. It may cause skin inflammation and rashes, if it is taken in high dose(904)
2. Since angelica root causes uterus constraction, the herb should be used on pregnant(904) unless with the approval of her herbalist(904).
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndrome and healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(827a) Diet and nutrition in polycystic ovary syndrome (PCOS): pointers for nutritional management by Farshchi H, Rane A, Love A, Kennedy RL(PubMed)
(828) The optimal diet for women with polycystic ovary syndrome? by Marsh K, Brand-Miller J.(PubMed)
(889) Inhibitory effects of Angelica sinensis
ethyl acetate extract and major compounds on NF-kappaB trans-activation
activity and LPS-induced inflammation by Chao WW, Hong YH, Chen ML, Lin
BF.(PubMed)
(890) Dang Qui(Complementary and Alternative Healing University)
(891) Angelica sinensis / Dong Quai(Golden Lotus Botanicals)
(892 Danggui to Angelica sinensis root: are potential benefits to European women lost in translation? A review by Hook IL1.(PubMed)
(893) Metabolomics study of hematopoietic function of Angelica sinensis on blood deficiency mice model by Li PL1, Sun HG1, Hua YL1, Ji P1, Zhang L1, Li JX1, Wei Y2(PubMed)
(894) Molecular screening of Chinese medicinal plants for progestogenic and anti-progestogenic activity by Ahmed HM1, Yeh JY, Tang YC, Cheng WT, Ou BR.(PubMed)
(895) Estrogenic activity of herbs commonly used as remedies for menopausal symptoms by Amato, Paula MD1; Christophe, Sylvie PhD2; Mellon, Pamela L. PhD(Menopause)
(896) Integrated standardization concept for Angelica
botanicals using quantitative NM by Received 9 July 2011, Revised 17
August 2011, Accepted 20 August 2011, Available online 1 September 2011(Sience direct)(894) [Experimental study on effects of 18 kinds of Chinese herbal medicine for synthesis of thromboxane A2 and PGI2].[Article in Chinese] by Wang SR1, Guo ZQ, Liao JZ.(PubMed)
(895) Polysaccharide isolated from Angelica sinensis inhibits hepcidin expression in rats with iron deficiency anemia by Liu JY1, Zhang Y, You RX, Zeng F, Guo D, Wang KP.(PubMed)
(896) [Hematopoietic effect of siwu decoction in the mice with blood deficiency induced by compound method of bleeding, starved feeding and exhausting].[Article in Chinese] by Tan W1, Song CS, Tan HL, Liu LL, Ma ZC, Wang YG, Gao Y.(PubMed)
(897) Chemical fingerprinting and quantitative constituent analysis of Siwu decoction categorized formulae by UPLC-QTOF/MS/MS and HPLC-DAD by Shulan Su1, Wenxia Cui12, Wei Zhou1, Jin-ao Duan1*, Erxin Shang1 and Yuping Tang(Chinese medicine)
(898) Study of the gastrointestinal protective effects of polysaccharides from Angelica sinensis in rats.
Cho CH1, Mei QB, Shang P, Lee SS, So HL, Guo X, Li Y.(PubMed)
(899) Glyphosate, pathways to modern diseases II: Celiac sprue and gluten intolerance by Samsel A1, Seneff S2.(PubMed)
(900) 36 Healing Herbs: The World's Best Medicinal Plants By Rebecca L. Johnson
(901) The antitumor effects of Angelica sinensis on malignant brain tumors in vitro and in vivo. by Tsai NM1, Lin SZ, Lee CC, Chen SP, Su HC, Chang WL, Harn HJ.(PubMed)
(902) A novel polysaccharide, isolated from Angelica sinensis (Oliv.) Diels induces the apoptosis of cervical cancer HeLa cells through an intrinsic apoptotic pathway. by Cao W1, Li XQ, Wang X, Fan HT, Zhang XN, Hou Y, Liu SB, Mei QB.(PubMed)
(903) Effects of a Chinese medical herbs complex on cellular immunity and toxicity-related conditions of breast cancer patients by Zhuang SR1, Chiu HF, Chen SL, Tsai JH, Lee MY, Lee HS, Shen YC, Yan YY, Shane GT, Wang CK.(PubMed)
(904) Dong Quai (the University of Marryland medical center)
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