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By Kyle J. Norton Health article writer and researcher; Over 10.000
articles and research papers have been written and published on line,
including world wide health, ezine articles, article base, healthblogs,
selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by
Disilgold.com Named 50 of the best health Tweeters Canada - Huffington
Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as
international journal Pharma and Bio science, ISSN 0975-6299.
What is Candida Albicans
Candida
albicans is a member of a large group of micro organism whose cells contain
complex structures enclosed within the membranes, including yeast(2)(3), fungi(4)(5)(6), and
mold(6) that live among the gut flora in the human mouth and
gastrointestinal tract. In fact, under normal circumstances, Candida
albicans that does not cause harmful effects, but overgrowth results in
candidiasis. Non-
albicans Candida
(NAC) species cause 35-65% of all candidaemias in the general patient
population(1). According to joint study, in many cases, biofilm(
microorganisms with cells stick to each other on a surface) formation(7) gene mutations(8) and overexpression of genes(9)(10) are often associated with increased
Candida resistance toward antifungal agents.
Causes of Candida Albicans
1. Amalgam filling
Amalgam filling is the use of amalgam as a
filling material
containing mainly mercury to treat cavity of your teeth by dentist. As a
highly toxic chemical(59)(60), mercury causes damage to the kidneys(61) and central
nervous system(62). Chelation therapy can be effective in removing all
forms of mercury from the body(63), but cannot reverse the damage of central
nervous system. As it weakens the immune system(64)(65), it can cause the over
growth of bad microorganisms, candidiasis(66)(67).
2. Anti fungus drugs
Antifungal
drug is a medication used to treat fungal infections and serious
systemic infections(68) by exploiting differences between mammalian and
fungal cells(69), to kill the fungal organism without dangerous effects on
the host(70). Unfortunately, people successfully treated with antifungal
drugs, 5 to 15% develop another infection in the next year(71)(72). The use of
the medication may also cause serious side effects associated with their use,
including liver damage(73), weakened immune system(74) and heart
failure(75)(76).
3. Genetic due to blood types and secretors status
3.1. Genetic mutations
a. People with
autosomal
dominant hyper-IgE syndrome, due to mutations in signal transducer and
activator of transcription1(STAT1)(78)(79), 3 (STAT3), a protein
responded to cytokines and growth factors, are at increased risk of
mucocutaneous
candidiasis caused by percentage of STAT1, STAT3 mutant neutrophils migrating into blisters and in peripheral
blood(77)(80).
b. Autoimmune regulator (AIRE) gene
Patient with
Autoimmune polyendocrine syndrome type 1 (APS-1) caused by mutations in the
autoimmune regulator (
AIRE)
gene,
may susceptible to risk of Chronic mucocutaneous candidiasis, due to
Increased IL-17A secretion, mediators of cellular inflammatory
responses, in response(81).
3.2. Blood types and secretors status
Secretors
status and blood types are defined as a person who secretes their blood
type antigens into body fluids and secretions such as the saliva,
mucus, etc. People with certain blood type and secretor status are
susceptible to mold allergies and molds. According to Rambam Medical
Center, individuals with blood group O with non-secretors of antigens
showed to have a higher carrier frequency of
Candida(82)(83). In dispute of that result, the study by Seoul National University, Korea indicted of no significantly related to blood group or secretor status in oral
Candida carriage(84)
4. Steroid in foods
Steroid
has been used for commercial profits in order to produce larger food
stock both in animals(85) and vegetation(86). Steroid in foods suppresses the
immune response such as medroxyprogesterone acetate (DMPA) in inhibition of innate and adaptive
immune mechanisms(87), thereby increasing colonization and promoting the
spread of candida(88)(89).
5. Blood sugar imbalance
Blood
sugar
imbalance cause fluctuation of glucose in the blood stream in patients
with diabetes, may lead to Candida albicans overgrowth, due to increased
extracellular enzyme activity(90) and production of hydrolytic
enzymes(91), as yeast
organisms craving for sugar, their natural diet.
6. Immune system deficiency
Immune
system deficiency allows candida over growth(92)(93) as it is not longer
perform its function in regulating the balance of all microorganism(94) in
the intestine track(95)(97).
7. Biochemical and metabolic individually
Slow
metabolizers' bodies chemistry is often more alkaline due to lower
production of lactic acid and low levels of gastric hydrochloric acid,
leading to constipation(96). The combination of these factors can result in
candida overgrowth(97).
8. Drugs due to suppress immune system during transplant
Drugs
suppressing immune system disrupt function of immune system in
rpoduction of T cells and phagocytic cells, and the cytokines that
mediate the interactions with fungal pathogen(98) and regulation the
balance of microorganism in the body(99)(100).
9. Stress
Stress
can cause insulin imbalance(101)(102) and weaken the liver(103) and
immune function(104), that allow unchecked of over growth candida
albicans(105)(106).
10. Deficiency of nutrient
Deficiency
of nutrient weakens the body systems in performing their function
properly, including the immune system in regulating the balance of
microorganism(107)(108).
11. Chronic use of antibiotics
Antibiotic therapy use are
known to increase the tendency for chronic infection due its
effect in killing bacteria indiscriminately, leading to bad
microorganism over growth(109)(110).
12. The pill
The use of the pill
can suppress the hormonal balance(111), causing fluctuation of sugar
levels(112) and significantly increasing the risk for candida yeast overgrowth(113).
14. Sexual transmitting diseases
Sex
with several partners without precautions increases the risk of
candida, if your partner happens to have a candida infection at the time
you have sex then you could get it too(114).
15. Acidity
Gastric
hydrochloric acid deficiency is widespread and allows yeast to
survive passage through the stomach, causing over growth of
candidiasis(115)(116).
16. Etc.
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