Sunday, 28 December 2014

Most common diseases of 50 plus - Diseases of Central Nervous system - The Preventive Do's and Do Not's list

By Kyle J. Norton Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

         Diseases of Central Nervous system

                           Dementia



About 5-8% of all people over the age of 65 have some form of dementia, and this number doubles every five years above that age. Dementia is the loss of mental ability, severe enough to interfere with people's every life and Alzheimer's disease is the most common type of dementia in aging people.

V.  Preventions
A. Do's and Do Not's list
 1. Mediterranean diet
If you are typical American dieter, you are at increased risk for the development of dementia when you get older as the diet is classified as one of the most unhealthy diet in the existence, according to studies. Mediterranean diet, high monounsaturated fatty acids energy intake appeared to be associated with a high protection against cognitive decline and reduced the prevalence of AD in older people(208). Also recent research supports the hypothesis of calorie intake, among other non-genetic factors, in influence of the risk of clinical dementia.(209).

2. Yoga  
Senile dementia is the mental deterioration, i.e, loss of intellectual ability associated with old age. Yoga is believed to have beneficial effects on cognition, probaby through attenuation of emotional intensity and stress reduction. Yoga participation showed to improve the memory performance, and all other psychophysiological parameters, in patient with dementia(3), including intellect, attention, thinking, comprehension and personality, with preservation of normal level of consciousness(210), according to G.J. Patel Ayurved College.

3. Aging of theory of mind
According to Aging of theory of mind, educational level and cognitive processing are two factors influencing the pattern of the aging.Younger and older group with equally high education outperformed the older group with less education in false-belief and faux-pas tasks, with younger group outperformed the other two groups in the cognitive processing tasks, according to Anhui Medical University(211)

3. Moderate alcohol drinking
Moderate alcohol drinking of less than 2 cups for men and 1 cups for women are said to offers possible health benefits(3), but Binge drinking (ie, alcohol exceeding the amount of 5 bottles of beer or a bottle of wine on 1 occasion at least monthly) in midlife is associated with an increased risk of dementia, according to the follow-up, 103 participants had developed dementia(212).

4.  Stop Smoking or never smoke before
Smoking is a risk factor for several life-threatening diseases, but its long-term association with dementia is controversial and somewhat understudied.  According to a total of 5367 people (25.4%), heavy smoking in midlife was associated with a greater than 100% increase in risk of dementia, AD, and VaD more than 2 decades later(213).

5. Drink you tea and coffee
Caffeine in tea and coffee may enhance cognitive function acutely, but its link to dementia is somewhat inconsistent, but most studies support coffee's favorable and protective effects against cognitive decline, dementia or AD. Coffee drinking of 3-5 cups per day at midlife was associated with a decreased risk of dementia/AD by about 65% at late-life(214).

6. Eat you fruits and veggies 
Fruits and veggies containing high amounts of antioxidant enhance the immune system in fighting against forming of free radicals cause to damage to the brain cells of that can lead to dementia. Vitamin E and vitamin C supplements in combination were associated with reduced prevalence and incidence of AD, according to The Johns Hopkins University(215).

7. Regular and moderate exercise for elder
 Regular and moderate exercise may attenuate  the cognitive dysfunctioning, but theirs' induced changes in cognition were not correlated with changes in mood/anxiety, probably through some separate neural systems mediation(216).

8.  Avoid nutritional deficiency with balance diet
a. Beyond our believe, an excess of dietary carbohydrates, particularly fructose, alongside a relative deficiency in dietary fats and cholesterol, may lead to the development of Alzheimer's disease(217).
b. For more of Avoid nutritional deficiency with balance diet, please visit(218)

9. Avoid environment risk of dementia
Certain environment toxins produced as a result of industrialization or naturally have been linked to cognitive degenerative diseases. According to University of British Columbia, novel environmental toxins: steryl glycosides, a potential etiological factor for age-related neurodegenerative diseases, showed   signs of mimicked ALS-PDC, including progressive deficits in motor, cognitive, and olfactory functions associated with neuron loss in the spinal cord, nigrostriatal system, cortex, hippocampus, and olfactory bulb in fed mice(219).

10. No illicit drug, please(220)
Illicit drug used may cause nervous system impairment as a result of direct and indirect effects on the integrity and function of nervous system tissue and, potentially, through immune effects, especially, up to 40% risk of nervous system impairment for patients with  HIV-1 infection.

11. Prevent prolonged period of using certain drug
As aging, accumulation of toxins of certain medication used to treat certain diseases, such as antidepressants, sedatives, cardiovascular drugs and anti-anxiety medications may cause increased risk of cognitive dysfunction causes of dementia-like symptoms(221).

12. Etc.
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References
(209) http://www.ncbi.nlm.nih.gov/pubmed/18466323
(210) http://www.ncbi.nlm.nih.gov/pubmed/22342535
(211) http://www.ncbi.nlm.nih.gov/pubmed/22408297
(212) http://www.ncbi.nlm.nih.gov/pubmed/22515730
(213) http://www.ncbi.nlm.nih.gov/pubmed/16222166
(214) http://www.ncbi.nlm.nih.gov/pubmed/20182054
(215) http://www.ncbi.nlm.nih.gov/pubmed/14732624
(216) http://www.ncbi.nlm.nih.gov/pubmed/22554780
(217) http://www.ncbi.nlm.nih.gov/pubmed/21402242
(218) http://healthyliving50over.blogspot.ca/2012/04/delay-dementia-causes-of-dementia.html
(219) http://healthyliving50over.blogspot.ca/2012/05/environment-toxin-causes-of-dementia.html
(220) http://healthyliving50over.blogspot.ca/2012/05/substance-abuse-causes-of-dementia.html
(221) http://healthyliving50over.blogspot.ca/2012/05/medication-causes-of-dementia.html


The Easy and Home made recipe: Smoked paprika mayonnaise

Posted By Kyle J. Norton 
  Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Recipe attributed to "Good Food to go- healthy lunch your kids will love" by Brenda Bradshaw and Cheryl Mutch, M.D. published by Random house Canada. You can view its website at randomhouse.ca 

1/3 cup mayonnaise
3/4 cup tbsp. smoke paprika
In small bowl, combine mayonnaise and paprika.
Yield 3/4 cup .


Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

For over 1000 healthy recipes, visit  http://kylejnorton.blogspot.ca/p/recipes.html

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Saturday, 27 December 2014

(Preview) Most common diseases of 50 plus - Diseases of Central Nervous system - The Complications of Dementia

By Kyle J. Norton Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

         Diseases of Central Nervous system

                           Dementia



About 5-8% of all people over the age of 65 have some form of dementia, and this number doubles every five years above that age. Dementia is the loss of mental ability, severe enough to interfere with people's every life and Alzheimer's disease is the most common type of dementia in aging people.

V. The Symptoms and Complications
B. The Complications
 According to physical complications of patients with dementia occurred in ward in the 12 months from April 2007 to March 2008 recorded in Ichinomiya City Hospital, Ichinomiya, the physical complications can be divided into two categories: (i) serious emergencies occurring in the ward with a possible high risk of mortality within a few days (e.g. pneumonia and upper airway obstruction); and (ii) life-threatening complications arising in the ward that required diagnosis and treatment by specialists from other medical departments (e.g. bone fracture and cancer)(202).
1. Pneumonia
 Pneumonia is common among patients with advanced dementia, especially toward the end of life, due to microbial  inffection, according to Beth Israel Deaconess Medical Center(203).

2. Obstructive Sleep Apnea Syndrome (OSAS) 
The prevalence of OSAS increased with aging, occurring in up to 25% of older adults and up to 48% in patients with Alzheimer's disease, showed to induce symptoms of hypoxia, fragmented sleep, daytime sleepiness, cognitive dysfunction, functional decline, and brain damage, due to reduced cerebral blood flow, ischemic brain lesions, microvascular reactivity, white matter lesions, and grey matter loss(204)

3. Bone fracture
Bone mass and dementia in elderly hip fracture patients may be associated to levels of different aluminium concentrations in water supplies in the areas affecting the negative calcium balance of age-related osteoporosis together predispose to senile dementia.(205)

4. Urinary incontinence
 Urinary incontinence is a common problem in dementia. Almost invariably, the person with dementia will develop incontinence as the disease progresses. However, the primary reasons for incontinence are often not because of any significant pathology in the urinary system. Rather, it is due to factors outside the urinary system, including insertion of tube in assisting urinary flow(206)

5. Venous thromboembolism
 Venous thromboembolism (VTE), caused by a blood clot breaking loose and traveling in the blood, in patients with dementia had a high incidence of fatal pulmonary embolism (PE) and fatal bleeding, according to the study of 37988 patients with 1316 (3.5%) having dementia(207).

6. Etc. 
Chinese Secrets To Fatty Liver And Obesity Reversal
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Optimal Health And Loose Weight

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html

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References
(202) http://www.ncbi.nlm.nih.gov/pubmed/20377817
(203) http://www.ncbi.nlm.nih.gov/pubmed/20625013
(204) http://www.ncbi.nlm.nih.gov/pubmed/20739254
(205) http://www.ncbi.nlm.nih.gov/pubmed/3239502
(206) http://www.ncbi.nlm.nih.gov/pubmed/16642241
(207) http://www.ncbi.nlm.nih.gov/pubmed/22374336

The Best and healthy recipe: The Dilly delicious Dip

Posted By Kyle J. Norton 
  Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Recipe attributed to "Good Food to go- healthy lunch your kids will love" by Brenda Bradshaw and Cheryl Mutch, M.D. published by Random house Canada. You can view its website at randomhouse.ca


1/2 cup mayonnaise
1/2 cup fat plain yogurt
2 tbsp. plus 1 tsp. finely chopped fresh dill
Kosher salt and freshly ground pepper
In small bowl, combine mayonnaise, yogurt and dill. Add salt and pepper to taste and refrigerate for at least 1 hour before serving.
Yield 1 cup

Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

For over 1000 healthy recipes, visit  http://kylejnorton.blogspot.ca/p/recipes.html

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Friday, 26 December 2014

(Preview) Most common diseases of 50 plus - Diseases of Central Nervous system - The Symptoms of Dementia

By Kyle J. Norton Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

         Diseases of Central Nervous system

                           Dementia



About 5-8% of all people over the age of 65 have some form of dementia, and this number doubles every five years above that age. Dementia is the loss of mental ability, severe enough to interfere with people's every life and Alzheimer's disease is the most common type of dementia in aging people.

IV. Symptoms and Complications of Dementia
Dementia is a neuropsychiatric disorder induced of cognitive impairment and behavioral disturbances. The behavioral and psychological symptoms of dementia (BPSD) are common, with a progressive loss of memory and other mental abilities, affecting a person's ability to perform usual tasks in everyday life.
A. Symptoms
A.1. Symptoms of Alzheimer's disease 
Alzheimer's disease is a brain disorder, affecting over 1 million people in US alone with well known  symptoms of lack of concentration (56%), tremors (56%), depression (44%), lack of cooperation (36%), and delusions (32%), psychotic symptoms (delusions, hallucinations, and delirium) and tremors, and emotional symptoms (tearfulness and apathy, lack of concentration and appetite change), according to Hospital de Cruces, Plaza de Cruces s/n, Barakaldo in a study of total of 1014 patients(177) and other symptoms of 

1. Increasing forgetfulness(178)
2. Communication difficulty(179)
3. Anxiety(180)
4. Mood and personal change(181)
5. Delay recall(183)
6. Repeat question(183)
7. Memory loss(182)
8 Aberrant motor behavior (184)
9. Sleep problems (184)
10. Eating problems (184) and
11. Agitation/aggression (184)
10. Etc.

A.2. Symptoms of Diminished quality of acetylcholine
If the nerves located in front of the brain perish, diminished quality of acetylcholine, it can cause language difficulty, memory loss, concentration problem and reduce mobile skills because of lacking reaction in muscular activity and refection.
Symptoms of deficiency of acetylcholine include(185)
1. Difficulty remembering names and faces after meeting people
2. Difficulty remembering peoples birthdays and numbers
3. Difficulty remembering lists, directions or instructions
4. Forgetting common facts
5. Trouble understanding spoken or written language
6. Forget where I put things 
7. Slowed and/or confused thinking
8. Difficulty finding the right words before speaking
9. Disorientation
10. Prefer to do things alone than in groups / social withdrawal
11. Rarely feel passionate
12. Feel despair and lack joy
13. Lost some of my creativity / lack imagination
14 Dry mouth
15. Etc.

A.3. Dementia due to long-term alcohol abuse
Dementia is common in patients with alcoholism. Most symptoms of alcohol dementia are also presented in other types of dementia, with a few qualitative differences(186) involved both cortical and subcortical pathology. According to the article, "What's alcohol-related dementia?" Alcohol dementia induced deterioration in intellectual function with memory not being specifically affected, such as disinhibition, loss of planning, and executive functions and a blithe disregard for the consequences of their behaviour,  affecting mostly of women in  the ages between 30 - 70  with the better rates better than for Korsakoff's Psychosis(187).
Other symptoms in deficits are most frequently observed on tasks of visuospatial function, memory(188) and higher-order (executive) tasks(189)

A.4. Multi-infarct dementia
Also known as vascular dementia, is the second most common form of dementia after Alzheimer's disease in older adults, caused by different mechanisms, affecting the vascular lesions in the brain.with major neurovegetative symptoms of depression unaccompanied by depressed mood/anhedonia in patients with clinically-diagnosed Alzheimer's disease (AD) and multi-infarct dementia (MID)(190).
Symptoms include memory deficits(192) such as
1. Confusion
2. Memory problems
3. Wandering Getting lost
and
4. At least one of behavioural or psychological symptom, such as appetite disturbances irritability and anxiety and emotional suppresion(such as laughing inappropriately, crying inappropriately)
(193), and
5. Difficulty following instructions, and 
6. Bladder incontinence
7. Bowel incontinence(191)

A.5. Dementia associated with Parkinson's disease
Parkinson disease (PD) is a disabling, progressive condition cause of cognitive deficits due to the interruption of frontal-subcortical loops that facilitate cognition and that parallel the motor loop, affecting motor function. These include olfactory deficit, sleep problems such as rapid eye movement behaviour disorder, constipation and male erectile dysfunction.(194).
Other symptoms due to to dopamine (DA) deficiency, include, dysexecutive behaviors(196), such as planning, abstract thinking, flexibility and behavioural control and postural disabilities(197) and
1. Constipation
2. Difficulty swallowing
3. Choking, coughing, or drooling
4. Excessive salivation
5. Excessive sweating
6. Loss of bowel and/or bladder control(195)

A.6. Creutzfeldt-Jakob disease (CJD)
People who have eaten contaminated beef in many years, may be infected with Creutzfeldt-Jakob disease (CJD) without even knowing it. Creutzfeldt-Jakob disease is a quickly progressing and fatal disease,  characterized by rapidly progressive dementia. Initially, individuals experience problems with muscular coordination, personality changes, including impaired memory, judgment, and thinking and impaired vision. People with the disease also may experience insomnia, depression, or unusual sensations.(198).

A.7. Subdural hematoma
 Subdural hemorrhages, the accumulation of blood beneath the outer covering of the brain resulted from the rupture of blood vessel may cause an increase in tracranial pressure, leading compression and damage to delicate brain tissue. Acute subdural hematoma has a high mortality rate.
Other symptoms include
1. Intermittent numbness and weakness of extremity(199) and
2. Loss of consciousnes(201)
3. Irritability
4. Seizures
5. Pain
6. Headache
7. Dizziness
8. Disorientation
9. Weakness
10. Weakness or lethargy
11. Nausea or vomiting
12. Loss of appetite
13. Personality changes
14. Confused speech
15. Difficulty with balance or walking
16. Altered breathing patterns
17. Hearing loss or hearing ringing (tinnitus)
18. Blurred Vision
19. Deviated gaze, or abnormal movement of the eyes(200)
20. Etc.

Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html

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References
(177) http://www.ncbi.nlm.nih.gov/pubmed/20920205
(178) http://www.ncbi.nlm.nih.gov/pubmed/21315756
(179) http://www.ncbi.nlm.nih.gov/pubmed/25356002
(180) http://www.ncbi.nlm.nih.gov/pubmed/16166409
(181) http://www.ncbi.nlm.nih.gov/pubmed/10796526
(182) http://www.ncbi.nlm.nih.gov/pubmed/25481271
(183) http://www.ncbi.nlm.nih.gov/pubmed/22122408
(184) http://www.ncbi.nlm.nih.gov/pubmed/25065098
(185) http://www.ncbi.nlm.nih.gov/pubmed/18849899
(186) http://www.nutritional-healing.com.au/content/articles-content.php?heading=Acetylcholine%20deficiency
(187) http://neurology.health-cares.net/alcohol-related-dementia.php
(188) http://www.ncbi.nlm.nih.gov/pubmed/25119654
(189) http://www.ncbi.nlm.nih.gov/pubmed/23347747
(190) http://www.ncbi.nlm.nih.gov/pubmed/22164676
(191) http://www.rightdiagnosis.com/m/multi_infarct_dementia/symptoms.htm
(192) http://www.ncbi.nlm.nih.gov/pubmed/24685627
(193) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006603/
(194) http://www.ncbi.nlm.nih.gov/pubmed/20642073
(195) http://www.helpguide.org/elder/parkinsons_disease.htm
(196) http://www.ncbi.nlm.nih.gov/pubmed/25511521
(197) http://www.ncbi.nlm.nih.gov/pubmed/25510818
(198) http://www.ninds.nih.gov/disorders/cjd/detail_cjd.htm#186463058
(199) http://www.ncbi.nlm.nih.gov/pubmed/11558288
(200) http://www.nlm.nih.gov/medlineplus/ency/article/000713.htm

The Best and healthy recipe: The Homemade Hummus

Posted By Kyle J. Norton Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Recipe attributed to "Good Food to go- healthy lunch your kids will love" by Brenda Bradshaw and Cheryl Mutch, M.D. published by Random house Canada. You can view its website at randomhouse.ca

1 can (540ml/190oz.) chick-peas, rinsed and drained, preserve 1/2 cup of the liquid
1/4 cup fresh lemon juice
1/4 cup tahini
2 - 3 garlic cloves, minced
1 tsp. ground cumin
Drizzled of extra-virgin olive oil
In bowl of food processor, place chickpeas, chickpeas liquid lemon juice, tahini, 2 garlic cloves, and cumin and process until smooth. Refrigerate for 30 minutes.
Taste and add another minced garlic clove if needed. To serve, drizzle with olive oil.
Yield 2 cups 

Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html

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Thursday, 25 December 2014

The Science of Soy - The East Viewpoints: Part A5 - Soy and Menopause Symptoms in Japanese

By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Soy foods, including tofu have been in traditional Chinese diet over thousands of year, according to Chinese literature. The reduced risk of chronic disease, including metabolic syndrome such as cardiovascular diseases, obesity and diabetes and lesser menopause symptoms in advanced age, may be aided by eating a lot of soy food accompanied with large portion of vegetables and fruits. Indeed, according to the study, only 10% of women in the East are experience symptoms of menopause in advanced age compared to over 70% of their Western counterparts.
According to Dr. Mark Messina, Ph.D., Soy foods contributed from 6.5%8 to 12.8%7 of total protein intake in older adult in Japan.(b)

The approval of cardiovascular benefit of soy by FDA in 1999 accompanied with the discovery of health benefits in clinical studies over past decade, prompted the promotion and advertisement of soy's health benefits in every aspect in Western society. Evidences could be seen by walking through the supermarkets and drug stores. Soy supplements and products such as tofu, soy milk, soy-based infant formula, and meatless “texturized vegetable protein” burgers were widely available. According to the United Soybean Board’s 2004–2005, 25% of Americans consume soy foods or beverages at least once per week, and 74% view soy products as healthy.

Today, the promotion of soy are no longer existed, it may be results of discovery of adverse effect in single ingredient and animal studies, as intake of soy is associated to induce risk certain mammary cancers and infertility. The publication of the result have drawn many criticisms. According to Thomas Badger, director and senior investigator at the Arkansas Children’s Nutrition Center in Little Rock, these effects are seen only under certain experimental conditions that are not likely to occur in humans—and therein lies the crux of the debate(a). Equol (4',7-isoflavandiol), an isoflavandiol metabolized from daidzein may be the causes, as 90% of Eastern population are equol producers but only 30% in the West.
The explanation of the positive effect of soy isoflavones in reduced risk of mammary cancers by University of Goettingen may be interesting, as researchers said" Most importantly, there is dispute as to whether isoflavones derived from soy or red clover have negative, positive or any effect at all on the mammary gland or endometrium. It is beyond any doubt that soy products may have cancer preventing properties in a variety of organs including the mammary gland. However, these properties may only be exerted if the developing organ was under the influence of isoflavones during childhood and puberty.

Soybean, the genus Glycine, belonging to the family Fabaceae, one of the legumes contains twice as much protein per acre than any other major vegetable or grain crop, native to Southeast Asia. Now, it is grown worldwide with suitable climate for commercial profits.
Nutrients
1. Carbohydrates
2. Dietary fiber
3. Fat
4. Protein
5. Essential amino acid
6. Vitamin A
7. Vitamin B6
8. Vitamin B12
9. Vitamin C
10. Vitamin K
11. Calcium
12. Iron
13. Magnesium
14. Phosphorus
15. Potassium
16. Sodium
17. Zinc
18. Etc.
Phytochemicals
1. Isoflavones
2. Genistein
3. Saponins
4. Beta-sitosterol
5. Daidzein

I. Soy in Eastern population
A. The Japanese population
Japan, an island nation in the Pacific Ocean, lies to the east of the Sea of Japan, China, North Korea, South Korea and Russia, stretching from the Sea of Okhotsk in the north to the East China Sea and Taiwan in the south(1c). According to Moriyama, Japanese women and men live longer and healthier than everyone else on Earth, it may be result of healthier Japanese diet and lifestyle. According to the World Health Organization, the Japanese have an average of 75 years healthy living with disability-free, it may be due to average soy intake 10 to 70 times higher than in Western people(1a)(1b).

A5. Soy and menopause symptom in Japan
Menopause is defined as a condition in which women have not had a menstrual period in a minimum of 12 months period as a result of the inactive ovaries, assuming the women are not pregnant and experience the ease of visible symptoms of menopause such as hot flashes and night sweats but not the invisible effects of menopause. During post menopause, any bleeding or spotting should be reported to your doctor immediately, because it may be caused by tumors rarely but it is possible. Symptoms may include Bleeding or spotting, Vagina itching and dryness, Hot flash, Bone pain and fracture, Bladder infection, Skin wrinkle, Hypertension, Bone density loss, etc.

Eppidemiological studies, linking soy effects on menopause symptoms have been inconclusive(1)(2)(3)(4). In Japanese women, phytochemicals in soy found effectively in reduced vasomotor symptoms of menopause. In the study of a supplement containing equol on the menopausal symptoms in Japanese, researchers at the Tokyo Medical and Dental University, showed that the equol-ingesting group, not only significantly reduces severity and frequency of hot flashes, neck or shoulder but also exhibited trends of improvement in sweating and irritability and a significant improvement in the somatic category symptoms(5). Administration of 10-mg natural S-(-)equol supplement consumed daily for 12 weeks  also indicated an reduction of hot flushes and neck or shoulder muscle stiffness, in postmenopausal Japanese women(6). And fermented soy products have been also showed to alleviate the severity of hot flushes(14).
Some researchers suggested that the effectiveness of soy isoflavone  in relieved symptoms of menopause may link to equol-producing status. In a 1-year double-blind, randomized trial in comparison of the effects of isoflavone (75 mg of isoflavone conjugates/day) in early postmenopausal equol-producer phenotype Japanese women, found that isoflavones exhibit the preventive effects on bone loss and fat accumulation in early postmenopausal women, depending on an individual's equol-producing capacity(7) and S-equol supplement improved mood-related symptoms in perimenopausal/postmenopausal even in equol nonproducers in Japan women, in total of 127 participants completed the trial(8).

Soy isoflavone extracts on testing on lumbar spine or hip BMD in menopausal women of controlled trials published in English, Japanese, or Chinese, showed a result of varying effects on spine BMD(9). In compared the symptom of hot flash and chilliness in menopause women, Dr. Melby MK. suggested that Japanese women are experience important vasomotor symptom than hot flushes and sweats, it may be result of dietary high in soy(10).

In Osteoporosis, menaquinone-7, the major chemical compound found in Japanese fermented soybeans, showed to prevent postmenopausal bone loss(11) and promote bone formation(13)(15) as well alleviating early postmenopausal women symptoms, such as in palpitation and backaches(15). Other study also suggested that intake of supplementation of isoflavones (ISO) regular associates to risk reduction of osteoporosis in  middle-aged Japanese and menopausal Japanese women(12).

In fact, according to the study of cross-sectional relationships of dietary and other lifestyle variables to menopause by the Gifu University School of Medicine, such as smoking,  calcium and soy product intakes, intakes of fat, cholesterol, and coffee were significantly associated with the onset menopause in Japanese women(16).

Taken altogether, High soy food intakes are associated to reduce symptoms of menopause in Japanese women, especially in the major menopausal symptom of chilliness. Intake of supplement containing equol are effective in symptom reduction even in non equol producers in these population as well. According to the Royal Hospital for Women, highest soy consumption in Japan lowered the rates of diseases, including breast, endometrial, colon and prostatic cancers atherosclerotic,  etc. The induced extremely high urinary levels of phytoestrogen metabolites may be a result of isoflavones in exhibited bioactivity when intake of high concentrations.(17)

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References
(a) The Science of Soy: What Do We Really Know? by Julia R. Barrett
(b) Guideline for healthy soy intake(the Unite Soybean board)
(1c) Japan, Wikipedia
(1a) Erdman JW Jr. AHA Science Advisory: soy protein and cardiovascular disease: a statement for healthcare professionals from the Nutrition Committee of the AHA. Circulation. 2000; 102: 2555–2559
(Soy protein and cardiovascular disease)
(1b) van der Schouw YT, Kreijkamp-Kaspers S, Peeters PH, Keinan-Boker L, Rimm EB, Grobbee DE. Prospective study on usual dietary phytoestrogen intake and cardiovascular disease risk in Western women. Circulation. 2005; 111: 465–471(Cardiovascular diseases in women)
(1) S-equol and the fermented soy product SE5-OH containing S-equol similarly decrease ovariectomy-induced increase in rat tail skin temperature in an animal model of hot flushes by Yoneda T1, Ueno T, Uchiyama S.(PubMed)
(2) A pilot study on the effects of S-equol compared to soy isoflavones on menopausal hot flash frequency by Jenks BH1, Iwashita S, Nakagawa Y, Ragland K, Lee J, Carson WH, Ueno T, Uchiyama S.(PubMed)
(3) Extracted or synthesized soybean isoflavones reduce menopausal hot flash frequency and severity: systematic review and meta-analysis of randomized controlled trials by Taku K1, Melby MK, Kronenberg F, Kurzer MS, Messina M.(PubMed)
(4) Treatment of vasomotor symptoms of menopause with black cohosh, multibotanicals, soy, hormone therapy, or placebo: a randomized trial by Newton KM1, Reed SD, LaCroix AZ, Grothaus LC, Ehrlich K, Guiltinan J.(PubMed)
(5) Equol improves menopausal symptoms in Japanese women by Aso T.(PubMed)
(6) A natural S-equol supplement alleviates hot flushes and other menopausal symptoms in equol nonproducing postmenopausal Japanese women by Aso T1, Uchiyama S, Matsumura Y, Taguchi M, Nozaki M, Takamatsu K, Ishizuka B, Kubota T, Mizunuma H, Ohta H.(PubMed)
(7) Possible role of equol status in the effects of isoflavone on bone and fat mass in postmenopausal Japanese women: a double-blind, randomized, controlled trial by Wu J1, Oka J, Ezaki J, Ohtomo T, Ueno T, Uchiyama S, Toda T, Uehara M, Ishimi Y.(PubMed)
(8) New equol supplement for relieving menopausal symptoms: randomized, placebo-controlled trial of Japanese women by Ishiwata N1, Melby MK, Mizuno S, Watanabe S.(PubMed)
(9) Effect of soy isoflavone extract supplements on bone mineral density in menopausal women: meta-analysis of randomized controlled trials by Taku K1, Melby MK, Takebayashi J, Mizuno S, Ishimi Y, Omori T, Watanabe S.(PubMed)
(10) Chilliness: a vasomotor symptom in Japan by Melby MK.(PubMed)
(11) Intake of fermented soybeans, natto, is associated with reduced bone loss in postmenopausal women: Japanese Population-Based Osteoporosis (JPOS) Study by Ikeda Y1, Iki M, Morita A, Kajita E, Kagamimori S, Kagawa Y, Yoneshima H.(PubMed)
(12) Soy isoflavone tablets reduce osteoporosis risk factors and obesity in middle-aged Japanese women by Mori M1, Aizawa T, Tokoro M, Miki T, Yamori Y.(PubMed)
(13) Promotion of bone formation by fermented soybean (Natto) intake in premenopausal women by Katsuyama H1, Ideguchi S, Fukunaga M, Fukunaga T, Saijoh K, Sunami S.(PubMed)
(14) Hot flushes and other menopausal symptoms in relation to soy product intake in Japanese women by Nagata C1, Shimizu H, Takami R, Hayashi M, Takeda N, Yasuda K.(PubMed)
(15) Soy intake related to menopausal symptoms, serum lipids, and bone mineral density in postmenopausal Japanese women by Somekawa Y1, Chiguchi M, Ishibashi T, Aso T.(PubMed)
(16) Association of diet and other lifestyle with onset of menopause in Japanese women by Nagata C1, Takatsuka N, Inaba S, Kawakami N, Shimizu H.(PubMed)
(17) Phytoestrogens and the menopause by Mackey R1, Eden J.(PubMed)