Saturday, 29 November 2014

Quick and #healthy #recipe: #Apple #Cinnamon #Oatmeal

Posted By Kyle J. Norton  Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Recipe contributed by Yum-O, the family cook book by Rachel Ray, Published by Clarkson Potter, New York.You can view her website at yum-o.org  



Swap
2 Granny smith apples, peeled, cored, and chopped, for the dried fruit

Add 2 teaspoons ground cinnamon, plus more for serving

Instructions
Follow the directions for the original recipe(click here), adding the cinnamon along with the apples. Serve with additional milk and a sprinkle of cinnamon.


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Friday, 28 November 2014

Women's Health - Premenstrual syndrome(PMS): The Adverse effects of Salt(Revised edition with references)

By Kyle J. Norton 
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

 Premenstrual syndrome is defined as faulty function of the ovaries related to the women's menstrual cycle, effected over 70% to 90% of women in the US and lesser for women in Southeast Asia because of difference in living style and social structure. The syndrome also interferes women's physical and emotional states, and daily activities as a result of hormone fluctuation and occurs one to two weeks before menstruation and then declines when the period starts.

1. Water retention
 Women with PMS are found to have low levels of potassium, increasing intake of sodium (salt)may enhance the abnormal function of pituitary gland(1) and lymphatic function(2)(3)causing  breast tenderness and water retention accordingly.

2. Adrenaline hormone
High sodium diet, increases the risk of over production of adrenaline hormone(4) effecting levels of blood sugar(5) in triggering more symptoms of PMS(6).

4. High blood pressure
High sodium diet for a prolong period of time causes high blood pressure(7), causes hydration and stiffness of the vascular wall(8) that interfere with the function of our in regulating the blood flow in the arteries and transport nutrients for brain health(9), leading nervous tension such as mood swing, anxiety and physical and emotional stress for some women with PMS.


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References
(1) http://en.wikipedia.org/wiki/Pituitary_gland(wikipedia)
(2) [Regulation of the interstitial fluid volume]. [Article in Japanese] by  Kawahara K1, Yasuoka Y, Kawada H.(PubMed)
(3) Impairment of lymphatic function in women with gynoid adiposity and swelling syndrome by L'Hermitte F1, Behar A, Pariès J, Cohen-Boulakia F, Attali JR, Valensi P.(PubMed)
(4) Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride by Graudal NA1, Hubeck-Graudal T, Jurgens G.(PubMed)
(5) Study on blood glucose concentration in patients with diabetes undergoing dental extraction under local anesthesia with and without adrenaline by Haji IU1, Siddiq M, Rao S, Rai G, Hiregoudar JS, Pitale U.(PubMed)
(6) [Correlation between neurotransmitters and neurosteroids and premenstrual syndrome patients of Gan-yang ascending syndrome and Gan-qi stagnation syndrome].[Article in Chinese] by Gao H1, Xia T, Qiao MQ.(PubMed)
(7) Sodium intake and hypertension by Karppanen H1, Mervaala E.(PubMed)
(8) Sodium in blood vessels. A brief review by Friedman SM.(PubMed)
(9) Nutrients and brain health: an overview by Spencer JP.(PubMed)

Quick and #healthy #recipe: #Banana #nut oatmeal

Posted By Kyle J. Norton  Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Recipe contributed by Yum-O, the family cook book by Rachel Ray, Published by Clarkson Potter, New York.You can view her website at yum-o.org  



Swap
1/2 cup pure maple syrup for the brown sugar
2 bananas, chopped, for the dried fruit

Add
3/4 cup toasted walnut pieces, chopped

Instructions
Follow the directions for the original recipe(click here), stirring in the chopped nuts just before serving the oatmeal. Top with additional milk if desired.
Serves 8


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Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html

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Thursday, 27 November 2014

Women's Health - Premenstrual syndrome(PMS): The Adverse effects of Smoking(Revised edition with references)

By Kyle J. Norton 
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

 Premenstrual syndrome is defined as faulty function of the ovaries related to the women's menstrual cycle, effected over 70% to 90% of women in the US and lesser for women in Southeast Asia because of difference in living style and social structure. The syndrome also interferes women's physical and emotional states, and daily activities as a result of hormone fluctuation and occurs one to two weeks before menstruation and then declines when the period starts.

The adverse effects of Smoking on premenstrual syndrome
1. Hormone imbalance
Smoking not only increases the risk of lung cancer(1), it also depletes the levels of good estrogen and exhibit the levels of bad estrogen(3) causing hormone imbalance resulting in increasing the risk of pre menstrual syndrome(4) and PMS symptoms(5) for some smoking women.

 2. Immune system
 Cadmium is very toxins(), it has an ability to attach to arteries wall(plagues)(8) and make the wall thinner, leading to increased cardiovascular mortality and increased incidence of cardiovascular disease(7) and decreasing heart function in blood transportation of nutrients and oxygen to our body cells need, which contributes to nutrients deficiency(9) cause of symptoms of premenstrual syndrome(10)

 3. Toxin accumulation
Cigarette contain high levels of toxic chemical compound(6) that may danger to your health including increasing nervous tension(11) and weakening the immune system(12) such as negative allergic reaction(12) and irregular cells growth(12), etc.

 4. Mineral deficiency
Cigarette contain high levels of cadmium which inhibits the minerals Ca, Zn, Se, Cr and Fe and deficiencies(13) causing minerals deficiency(9) elevating symptoms of PMS.

 5. Vitamin deficiency
Women with premenstrual syndrome are found to have a low levels of B vitamins(14), namely
Thiamine, riboflavin, niacin, vitamin B-6, folate, and vitamin B-12. Smoking decreased concentrations of several antioxidant vitamins, thus increasing risk of premenstrual syndrome(15).


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References
(1) Lifetime probability of developing lung cancer, by smoking status, Canada by Villeneuve PJ1, Mao Y.(PubMed)
(2) Predicting lung cancer deaths from smoking prevalence data by Winkler V1, Ng N, Tesfaye F, Becher H.(PubMed)
(3) Impact of smoking on estrogenic efficacy by Ruan X1, Mueck AO.(PubMed)
(4) Association of menstrual phase with smoking behavior, mood and menstrual phase-associated symptoms among young Japanese women smokers by Sakai H1, Ohashi K.(PubMed)
(5) Global epidemiological study of variation of premenstrual symptoms with age and sociodemographic factors by Dennerstein L1, Lehert P, Heinemann K.(PubMed)
(6) Toxic metal concentrations in cigarettes obtained from U.S. smokers in 2009: results from the International Tobacco Control (ITC) United States survey cohort by Caruso RV1, O'Connor RJ2, Stephens WE3, Cummings KM4, Fong GT5.(PubMed)
(7) Cadmium exposure and incident cardiovascular disease by Tellez-Plaza M1, Guallar E, Howard BV, Umans JG, Francesconi KA, Goessler W, Silbergeld EK, Devereux RB, Navas-Acien A.(PubMed)
(8) Metal pollutants and bioelements: retrospective of interactions between magnesium and toxic metals by Soldatovic D1, Matovic V, Vujanovic D, Guiet-Bara A, Bara M, Durlach J.(PubMed)
(9) [Nutrition and chronic alcohol abuse]. [Article in Spanish] Moreno Otero R1, Cortés JR.(PubMed)
(10) Zinc and copper levels in premenstrual syndrome. Chuong CJ1, Dawson EB.(PubMed)
(11) Assessment of narghile (shisha, hookah) smokers' actual exposure to toxic chemicals requires further sound studies by Chaouachi K.(PubMed)
(12) Effects of cigarette smoking on the immune system. Follow-up studies in normal subjects after cessation of smoking by Hersey P, Prendergast D, Edwards A.(PubMed)
(13) Molecular basis of cadmium toxicity by Nath R, Prasad R, Palinal VK, Chopra RK.(PubMed)
(14) Long- and short-term effects of tobacco smoking on circulating concentrations of B vitamins by
Ulvik A1, Ebbing M, Hustad S, Midttun Ø, Nygård O, Vollset SE, Bønaa KH, Nordrehaug JE, Nilsen DW, Schirmer H, Ueland PM.(PubMed)
(14) Dietary B vitamin intake and incident premenstrual syndrome by Chocano-Bedoya PO1, Manson JE, Hankinson SE, Willett WC, Johnson SR, Chasan-Taber L, Ronnenberg AG, Bigelow C, Bertone-Johnson ER.(PubMed)

Quick and #healthy #recipe: Dried #Fruit Oatmeal

Posted By Kyle J. Norton  Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Recipe contributed by Yum-O, the family cook book by Rachel Ray, Published by Clarkson Potter, New York.You can view her website at yum-o.org  


Ingredients
3 cups of old fashioned (not instant) oatmeal
 3 cups skim milk, plus more for serving
1/2 half cup brown sugar
1/2 cup dried dates, chopped
1/2 cup currants or raisins
1/2 teaspoon salt

Instructions

Combine oatmeal, milk, and 4 cups water in large, deep saucepan and bring to a boil over medium-high heat. When it boils, quickly turn the heat down to very low. Stir in brown sugar, dried fruits and salt and cook at a low simmer for 15 to 20 minutes, or until very thick and creamy. Stir often to prevent the bottom from scorching.
Serve with additional milk, or cool and refrigerate to reheat later in the wee;.
Serves 8



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Wednesday, 26 November 2014

(Preview) Most common diseases of 50 plus - Thyroid Disease - Hashimoto’s thyroiditis : Preventions, Managements and Treatments

By Kyle J. Norton 
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                                          Thyroid disease
          Thyroid disease is defined as a condition of malfunction of thyroid gland.

     Thyroid disease : Hashimoto’s thyroiditis

Hashimoto’s thyroiditis (chronic lymphocytic thyroiditis) is an autoimmune disease in which the immune system attacks the thyroid gland, causing an underactive thyroid gland (hypothyroidism).
According to the study by the University of Pisa, Women with Hashimoto’s thyroiditis (HT) suffer from symptoms independently from hypothyroidism and regardless thyroid dysfunction(a).

A. Symptoms
1. Dysphagia, shortness of breath, voice changes, and odynophagia
 According to the ata of patients who underwent thyroidectomy from 2005 through 2009, by the Medical University of South Carolina, 52%,  26% and 8% of patients experienced symptoms of dysphagia and shortness of breath; voice changes, and complained of odynophagia, respectively(1).

2. Anxiety, negative mood, depression, dry skin, cold intolerance, puffy eyes, muscle cramps and fatigue, deep voice, constipation, slow thinking and poor memory.
Hashimoto’s thyroiditis is a common auto-immune disorder. The most common presenting symptoms may include anxiety, negative mood, depression, dry skin, cold intolerance, puffy eyes, muscle cramps and fatigue, deep voice, constipation, slow thinking and poor memory, according to the study by the Leiden University Medical Center(2).

3. General health
Women with Hashimoto’s thyroiditis (HT) also with positive anti-thyroid autoantibodies(anti-TPO) are experience to a significantly higher prevalence of general health symptoms as compared to those without HT(2a).

4. Other symptoms
Swelling in front of the neck along with constipation, anorexia, weight gain and increasing pallor may also be symptoms of hypothyroid goiter (autoimmune thyroiditis, Hashimoto’s thyroidits), due to high level of  thyroid stimulating hormone (TSH), low level of  T4 with presence of thyroid specific antibodies in blood(2b).

B. Causes
1. Autoimmune disorder
The current knowledge on Hashimoto’s thyroiditis associated with concept of autoimmune thyroid disease is caused by autoimmune process in stimulation of  abnormal production of antibodies, reacting with thyroglobulin and thyroid peroxidase(3a).

2. Primary hyperparathyroidism (PHPT)
Patients with primary hyperparathyroidism (PHPT) are susceptible to develop Hashimoto’s thyroiditis due to similar autoimmune inflammatory process with the rate ofoccurrenceof 1.89%(3).

2. Cerebellar ataxia
Both hypothyroidism and Hashimoto’s thyroiditis (HT) can rarely be associated with cerebellar ataxia.
but patients with hypothyroidism with history of severe essential tremor may develop Hashimoto’s thyroiditis(4).

C. Risk factors
1. Childhood weight gain and childhood overweight
Childhood weight gain and childhood overweight conferred an increased risk to later hypothyroidism and thyroid autoimmunity, particularly in women, according to the study by the Medical Research Council Unit for Lifelong Health and Ageing(5).

2. Genetic factors
CTLA-4 gene located in chromosome 2q33 region has a strong association with several autoimmune diseases, including Hashimoto’s thyroiditis(6).

3. Female
If you are female with type I diabetes, you are at increased risk for the development of HT,
according to the study of thyroid autoimmunity in a very large nationwide cohort of children and adolescents with type 1 diabetes, 63% of type I diabetes patients with positive antibodies were girls, compared with 45% of patients without antibodies(7).

4. Other risk factors
According to the study by the Kaunas University of Medicine, pregnancy, drugs, age, sex, infection, and irradiation may also be associated to the risk factors of Hashimoto's thyroiditis (HT)(8).

D.  Diseases associated to Hashimoto’s thyroiditis
1. Hashimoto’s encephalopathy (HE)
Hashimoto’s encephalopathy (HE) is a rarely recognized neurocognitive syndrome associated with thyroid autoimmunity and occurred more common in women(14).

2. Neurofibromatosis Type 1
Hashimoto’s thyroiditis is a common form of chronic autoimmune thyroid disease (AITD) and often coexists with other autoimmune diseases, including Hashimoto’s thyroiditis(15).

3. Chronic hepatitis C(CHC)
The prevalence of of thyroid dysfunction is significantly higher among Chronic hepatitis C patients with Hashimoto’s thyroiditis(HT) than CHC patients without HT(16).

4. Reactive thrombocytosis
 Reactive thrombocytosis, an elevated platelet count (> 450,000/μL) developed secondary to another disorder, including Hashimoto’s thyroiditis and/or subclinical hypothyroidism(17).

5. Thyroid papillary carcinoma
Patients with Thyroid papillary carcinoma are associated to 26.8% risk of HT without differences in relation to tumor size(18).

E. Misdiagnosis
Although fine-needle aspiration (FNA)is extremely valuable in the initial evaluation of thyroid lesions,  with an accuracy of 98.6% and 80% positive predictive value, and 100% negative predictive value, misdiagnosis can be abserved(19).

1. Overlapping thyroid follicular lesions coexisting with Hashimoto’s thyroiditis
 Overlapping cytological features of FN and HT were showed to be the main causes of false-positive results in diagnosis of thyroid follicular lesions coexisting with Hashimoto’s thyroiditis' dominant in some patients, if not taken account of presented forms of follicular-cell  and/or moderate to excessive numbers of lymphoid cells(20).

2. Papillary thyroid carcinoma (PTC)
An association between papillary thyroid carcinoma (PTC) and Hashimoto’s thyroiditis (HT) is well recognized, but papillary thyroid carcinoma (PTC)  is most often misdiagnosed as either follicular neoplasm or colloid nodule with or without HT(21).

3. Follicular adenoma, nodular goiter, macrofollicular adenoma and malignant lymphoma
 Hashimoto’s thyroiditis (HT) can be misdiagnosed as follicular adenoma, nodular goiter, macrofollicular adenoma and malignant lymphoma, if  FNABs an associated lesion was not sampled or some of the cellular features of HT were misinterpreted(22).

4. Solitary thyroid nodule
 Solitary thyroid nodule also can be misdiagnosed as Hurthle cell neoplasm on FNAC in patients of Hashimoto’s thyroiditis with marked Hurthle cell change(22a).

F.  Diagnosis
After recording the past and present history and completing a physical exam, including assessing symptoms and complaints commonly seen in hypothyroidism and neck examination. The tests which your doctor orders may include
1. Blood test
The aim of the test is to determine the level of thyroid function. Underactive thyroid gland is presented with the low level of thyroid hormone with elevated TSH as your pituitary gland tries to stimulate your thyroid gland to produce more thyroid hormone.

2. An antibody test
The aim of the test is to check for the presence of antibodies against thyroid peroxidase, the an enzyme which plays an important role in the production of thyroid hormones.

3. Thyroid scan
Thyroid scan in Hashimoto’s thyroiditis can mimic a wide range of thyroid disorders, due to overlapping (23).

4. Fine needle aspiration cytology
FNAC can accurately diagnose Hashimoto’s thyroidits in most patients. However, a small percentage of cases may be missed due to the limitations of this procedure and the varied sell structures of the disease (24).

G. Prevention
G.1. Diet to prevent Hashimoto’s thyroiditis

1. Brazil Nuts and Sunflower Seeds
Selenium found abundantly in Brazil Nuts and sunflower seeds was significantly related to the production of thyroid gland. A low selenium status significantly increased the risk for thyroid enlargementand and  development of multiple nodules(25a). Overdose may have a toxic effect on growth hormone, causing adverse effects of anorexia, diarrhea, depression, hemorrhage, liver and kidney necrosis, blindness, ataxia and respiratory disturbances(25).

2. Sea buckthorn
Sea buckthorn (Hippophae rhamnoides L.) constitutes thorny nitrogen fixing deciduous shrub. Sea buckthorn(SBT) is primarily valued for its very rich vitamins A, B(1), B(12), C, E, K, and P; flavonoids, lycopene, carotenoids, and phytosterols. and therapeutically important since it is rich with potent antioxidants. Scientifically evaluated pharmacological actions of SBT are like inflammation inhibited by reduced permeability, loss of follicular aggregation of lymphocytes from the inflamed synovium and suppress lymphocyte proliferation(26).

3. Balanced diet
Several trace minerals, including iodine, iron, selenium, and zinc. and trace elements are essential for normal thyroid hormone metabolism, Coexisting deficiencies of these elements can impair thyroid function. Iron deficiency impairs thyroid hormone synthesis and reduces the efficacy of iodine. Combined selenium and iodine deficiency leads to severely stunted physical and mental growths(27).

G.2. Phytochemicals and Antioxidants to prevent and treat Hashimoto’s thyroiditis
Patients with in Hashimoto’s thyroiditis (HT)  were found to significant increase in oxidative stress parameters in serum and LDL-fraction(28).
1. Resveratrol
Resveratrol, found in skin and seed of grape regulates several biological processes, including sell cycle arrest, in both papillary and follicular thyroid cancer. resveratrol also influences thyroid function by enhancing iodide trapping and increasing TSH secretion(29).

2. Polyphenolic flavonoids
Polyphenolic flavonoids found in black and green tea extracts showed to alter the thyroid gland physiology and architecture, including inhibited enlargement of thyroid gland, decreased serum T3 and T4, and a parallel increase in serum thyroid stimulating hormone (TSH) at green tea extract at 2.5 g% and 5.0 g% doses and black tea extract at 5.0 g% dose(30).

3. Selenium
According to the study by the Hôpital du Cluzeau, selenium supplementation decreases anti-thyroid antibody levels and improves the ultrasound structure of the thyroid gland(31).

2. Vitamin D
Vitamin D deficiency may have a role in the autoimmune process in Hashimoto thyroiditis in children.
 Children with Hashimoto thyroiditis showed to associate with higher vitamin D deficiency rates in comparison to vitamin D levels in the Hashimoto group(32).

H. Treatments
A. In conventional Medicine
1. Levothyroxine therapy
Beside monitoring thyroid functions of the patients with HT periodically for hypothyroidism, treatment of Levothyroxine therapy is necessary to improve positively affect the clinical course of the disease and the antibody titers(33).

2. Combination of liothyronine (T3) and levothyroxine
Although ombinations of levothyroxine plus liothyronine appear to have beneficial effects on the mood, quality of life, and psychometric performance of the patients over levothyroxine alone with the possibility of adverse effects, large sample size is necessary for further study(34).

H.2.In Herbal Medicine
1. Alkaloid tetrandrine
According to the study by the Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, TTetrandrine (Tet), purified from a creeper Stephania tetrandra S Moore, used to treat patients with silicosis, autoimmune disorders, and hypertension in Mainland China for decades. exhibited a wide variety of immunosuppressive effects both in vitro and in vivo(38).

2. Salvia miltiorrhiza, Tripterygium wilfordi, Tanacetum parthenium and Curcuma longa
A number of herbal products used for their immunosuppressive effects, may be useful in immune-mediated disorders including autoimmune diseases and organ transplant rejection, including  Salvia miltiorrhiza and Tripterygium wilfordii functions in reduced inflammatory cytokines and mediators, Tanacetum parthenium function in  inhibited the release of pro-inflammatory mediators and Curcuma longa function in down regulates the expression of inflammation(39).

3. Radix Bupleuri
Radix Bupleuri, used most frequently prescribed crude herbs in the prescriptions of traditional Chinese medicine for the treatment of inflammatory diseases and auto-immune diseases showed to inhibit production of serum autoantibodies and total immunoglobulin G (IgG) with doses depended for 35 days
(40).

4. Polygonum multiflorum and Artemisia scoparia
According to the study by the National Taiwan University, emodin and scoparone, the active principles isolated from Polygonum multiflorum and Artemisia scoparia, respectively, both exhibit vasorelaxant and immunosuppressive effects. In dose depended the phytochemicals also suppressed the responses of white blood cells with a one-lobed nucleus, and cell proliferation(41).

H.3.  In traditional Chinese Medicine
1. Aconite cake-separated moxibustion and option the better therapeutic program
Application of aconite cake-separated moxibustion therapy with acupoints of [(1) Danzhong (CV 17), Zhongwan (CV 12), Guanyuan (CV 4); (2) Dazhui (GV 14), Shenshu (BL 23), Mingmen (GV 4)] alternatively with oral administration of 25 microg Euthyrox everyday, showed to improve clinical symptoms and thyroid function in patients of Hashimoto’s thyroiditis, in comparison of simple oral administration of Euthyrox (levothyroxine)(35).

2. Brown seaweed Sargassum
 Sargassum spp., a brown seaweed, used in Traditional Chinese Medicine (TCM) to treat a variety of diseases over 2000 years including thyroid disease, exhibited its immunomodulator effects and could be useful in the treatment of thyroid related diseases such as Hashimoto’s thyroiditis(36).

Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight

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References
(1) http://www.ncbi.nlm.nih.gov/pubmed/22191404
(2) http://www.ncbi.nlm.nih.gov/pubmed/23744563
(2a) http://www.ncbi.nlm.nih.gov/pubmed/21112862
(2b) http://www.ncbi.nlm.nih.gov/pubmed/21381622 
(3a) http://www.ncbi.nlm.nih.gov/pubmed/19667753
(3) http://www.ncbi.nlm.nih.gov/pubmed/23865082
(4) http://www.ncbi.nlm.nih.gov/pubmed/23439792
(5) http://www.ncbi.nlm.nih.gov/pubmed/23436917
(6) http://www.ncbi.nlm.nih.gov/pubmed/22851994
(7) http://www.ncbi.nlm.nih.gov/pubmed/12145233
(8) http://www.ncbi.nlm.nih.gov/pubmed/19667753 
(14) http://www.ncbi.nlm.nih.gov/pubmed/23767389
(15) http://www.ncbi.nlm.nih.gov/pubmed/23691379
(16) http://www.ncbi.nlm.nih.gov/pubmed/23663880
(17) http://www.ncbi.nlm.nih.gov/pubmed/23518829
(18) http://www.ncbi.nlm.nih.gov/pubmed/23306572
(19) http://www.ncbi.nlm.nih.gov/pubmed/22619157
(20) http://www.ncbi.nlm.nih.gov/pubmed/12508180
(21) http://www.ncbi.nlm.nih.gov/pubmed/11403259
(22) http://www.ncbi.nlm.nih.gov/pubmed/10349369
(22a) http://www.ncbi.nlm.nih.gov/pubmed/22090699 
(23) http://www.ncbi.nlm.nih.gov/pubmed/2847097
(24) http://www.ncbi.nlm.nih.gov/pubmed/22090699 
(25) http://www.ncbi.nlm.nih.gov/pubmed/20883174
(25a) http://www.ncbi.nlm.nih.gov/pubmed/21242171
(26) http://www.ncbi.nlm.nih.gov/pubmed/22530142
(27) http://www.ncbi.nlm.nih.gov/pubmed/12487769
(28) http://www.ncbi.nlm.nih.gov/pubmed/22951187
(29) http://www.ncbi.nlm.nih.gov/pubmed/21946130
(30) http://www.ncbi.nlm.nih.gov/pubmed/20801949
(31) http://www.ncbi.nlm.nih.gov/pubmed/23046013
(32) http://www.ncbi.nlm.nih.gov/pubmed/22876540
(33) http://www.ncbi.nlm.nih.gov/pubmed/22155461
(34) http://jcem.endojournals.org/content/90/8/4946.full
(35) http://www.ncbi.nlm.nih.gov/pubmed/?term=Hashimoto+thyroiditis+in+TCM
(37) http://www.ncbi.nlm.nih.gov/pubmed/2268942 
(38) http://www.ncbi.nlm.nih.gov/pubmed/12466046
(39) http://www.ncbi.nlm.nih.gov/pubmed/22761185
(40) http://www.ncbi.nlm.nih.gov/pubmed/19467314
(41) http://www.ncbi.nlm.nih.gov/pubmed/1830846

Women's Health - Premenstrual syndrome(PMS): The Adverse effects of Caffeine(Revised edition with references)

By Kyle J. Norton 
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

 Premenstrual syndrome is defined as faulty function of the ovaries related to the women's menstrual cycle, effected over 70% to 90% of women in the US and lesser for women in Southeast Asia because of difference in living style and social structure. The syndrome also interferes women's physical and emotional states, and daily activities as a result of hormone fluctuation and occurs one to two weeks before menstruation and then declines when the period starts.

Caffeine
1. Vitamins and minerals deficiency
Food containing caffeine also contains tannin(1) which block the digestive system in absorbing of vitamins and minerals in the digestive tract(1)t including iron, zinc, copper(2), magnesium(3), etc.,  the vital vitamins and minerals for women with PMS.

2. Unbalance of blood sugar
Caffeine is a stimulant, it helps to improve the function of nervous system(4) if it is taken in a right dose. Over dose of caffeine causes suddenly surge and fall of blood sugar(5) in the blood stream resulting in over production of adrenaline hormone(6)(7) leading to symptoms of PMS(8).

3. Methylxathines
Methylxathines in food containing caffeine inhibits the actions of sleepiness induces adenosine(11) and treat symptoms of asthma(12)(13), but may exhibit side effects of breast tenderness(9), begnin lumps(9)(10) and breast pain(10).

4. Theophylline and theobromine
Foods containing caffeine also contains methylxathines and theobromine which contrite to relaxed muscle(14) and improved blood pressure, if they are taken in small dose. Over dose of methylxathines and theobromine may increase the risk of blood sugar unbalance(15) leading to over production adrenaline hormone(16) causes of PMS symptoms(8).

5. Addictive
Caffeine is so additive(17),. It narrows your blood vessels(18) when taken. complete stop suddenly may induce symptoms of greater sleepiness, lower mental alertness, and poorer performance on simple reaction time, choice reaction time and recognition memory tasks, etc.(19). It is wise to stop it slowly over a period of time.


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References
(1) Assessment of Anti-nutritive Activity of Tannins in Tea By-products Based on In vitro Rumen Fermentation by Kondo M1, Hirano Y2, Ikai N3, Kita K4, Jayanegara A5, Yokota HO3.(PubMed)
(2) [Factors which modify the nutritional state of iron: tannin content of herbal teas].[Article in Spanish] by Pizarro F1, Olivares M, Hertrampf E, Walter T.(PubMed)
(3) Rhubarb tannins extract inhibits the expression of aquaporins 2 and 3 in magnesium sulphate-induced diarrhoea model by Liu C1, Zheng Y2, Xu W2, Wang H2, Lin N1.(PubMed)
(4) Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic and psychostimulant effects by Nehlig A1, Daval JL, Debry G.(PubMed)
(4) [Comparison of caffeine citrate and aminophylline for treating primary apnea in premature infants].[Article in Chinese] by Xu JL1, Wang RQ, Chen DM.(PubMed)
(5) Caffeine's impairment of insulin-mediated glucose disposal cannot be solely attributed to adrenaline in humans by Battram DS1, Graham TE, Dela F.(PubMed)
(6) Adrenaline rush: the role of adrenergic receptors in stimulant-induced behaviors by Schmidt KT1, Weinshenker D.(PubMed)
(7) [Correlation between neurotransmitters and neurosteroids and premenstrual syndrome patients of Gan-yang ascending syndrome and Gan-qi stagnation syndrome].[Article in Chinese] by Gao H1, Xia T, Qiao MQ.(PubMed)
(8) Adrenaline rush: the role of adrenergic receptors in stimulant-induced behaviors by Schmidt KT1, Weinshenker D.(PubMed)
(9) Methylxanthines and benign breast disease by Schairer C, Brinton LA, Hoover RN.(PubMed)
(10) Caffeine restriction as initial treatment for breast pain by Russell LC.(PubMed)
(11) Effect of caffeine on intravenous adenosine-induced hyperemia in fractional flow reserve measurement by Matsumoto H1, Nakatsuma K, Shimada T, Ushimaru S, Mikuri M, Yamazaki T, Matsuda T.(PubMed)
(12) [Asthma bronchiale: lung function is affected by coffeine].[Article in German] by Dinh QT1, Bals R.(PubMed)
(13) Can we find better bronchodilators to relieve asthma symptoms? by Townsend EA1, Yim PD, Gallos G, Emala CW.(PubMed)
(14) Opposite actions of caffeine and creatine on muscle relaxation time in humans by Hespel P1, Op't Eijnde B, Van Leemputte M.(PubMed)
(15) Differential effects of methylxanthines on local cerebral blood flow and glucose utilization in the conscious rat by Grome JJ, Stefanovich V.(PubMed)
(16) Mood, alertness and sympathetic-adrenal medullary activity during the menstrual cycle by Pátkai P, Johannson G, Post B.(PubMed)
(17) The buzz: is caffeine addiction real?[No authors listed](PubMed)
(18) Effects of chronic administration of ethanolic extract of kolanut (Cola nitida) and caffeine on vascular function by Salahdeen HM, Omoaghe AO, Isehunwa GO, Murtala BA, Alada AR.(PubMed)
(19) Faster but not smarter: effects of caffeine and caffeine withdrawal on alertness and performance by Rogers PJ1, Heatherley SV, Mullings EL, Smith JE.(PubMed)