Salad Recipe - Spinach Make ahead

Company Coming salads  by Jean Pare

 This is a green that can be made "the day before"

6 cups (1.5 L) spinach leaves, torn, lightly packed
1/2 cup (125ml) grated or cubed Swiss cheese
1/2 cup (125 ml) grated or cubed Cheddar cheese
2 cups (500 ml) sliced fresh mushroom
4 hard-boiled eggs, sliced

1 cup (250 ml) salad dressing (mayonnaise)
1/2 cup (125 ml) sour cream
3 tbsp. (50ml) milk
2 tsp. (10ml) lemon juice
2 tsp. (10ml) granulated sugar
1/4 cup (50ml) thinly slice green onions
4 bacon slice, cooked and crumbled

Arrange torn green spinach leaves in bottom of the medium size glass bowl. Put grated cheese on top. Spread mushrooms over cheese. Cover with sliced eggs.
In a small cream well, salad dressing, sour cream, milk, lemon juice and sugar. Stir in onions. Bread over top of salad right to the slices of bowl. Cover. Chilled overnight.
To serve remove cover, sprinkle bacon over top. Serve 8.

Romaine make ahead: Omit spinach and use Romaine lettuce in above salad. Every bit as good.

Variation: Omit salad dressing and sour cream. Add 8 oz. (250g) cream cheese mixed with1/2 cup (125 ml) sour cream



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Cervical cancer in Vitamin B6 Points of View

Kyle J. Norton  

Epidemiological studies focusing vitamin B6 in reduced risk of cervical  cancer have produced conflict results(a)(b)(c)(d). According to the American Cancer Society's, in 2014, 12,360 new cases of invasive cervical cancer will be diagnosed with the death of  4,020 patients. The risk of cervical cancer is higher in Hispanic women followed by African-Americans, Asians and Pacific Islanders, and whites(e).
Vitamin B6, also known as pyridoxine, is a water soluble vitamin found abundantly in green peas, yams, broccoli, asparagus and turnip greens, Peanuts, sunflower seeds, cashews and hazelnuts, meat, fish etc., with functions of amino acid, carbohydrate  metabolism, brain health, and liver detoxification, etc.

Suggestions of polymorphisms in genes related to folate metabolism modify the association of dietary and circulating folate and vitamin B-6 with cervical neoplasia, according to the study of Dr.Cardoso MA and the research team(1). In the study of Vitamin B6 status in patients with cancer of the uterine cervix, researchers found that  23-35%the patients with cervical cancer, a 23-35% are associated with deficiency of vitamin B6(2). Other in the research of serum homocysteine  and cervical cancer risk indicated a strongly and significantly predictive of invasive cervical cancer risk associated with folate, B12 and/or B6 inadequacy, or genetic polymorphisms affecting one-carbon metabolism(3). In a multiethnic case-control study for examination of the association of dietary folate and MTHFR genotype with the odds ratios (ORs) for cervical dysplasia among women identified from several clinics on Oahu, Hawaii, between 1992 and 1996 indicated that dietary intakes of folate, vitamin B(6), and vitamin B(12) were inversely related to the ORs for cervical squamous intraepithelial lesions (SILs)(4). The study at the University of Arizona, showed that folate, vitamin B12, vitamin B6, and methionine may function to prevent cervical cancer through their role in DNA methylation(5)

Taken altogether, intake of Vitamin B6 may be related to reduced risk of cervical cancer in patients with deficiency and through its function in in DNA methylation. Over doses may induced the symptoms of difficulty coordinating movement, numbness, sensory changes, etc., please make sure you follow the guideline of the Institute of Medicine of the National Academies. As always, all articles written by Kyle J. Norton are for information & education only, please consult your Doctor & Related field specialist before applying



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References
(a) Diet and premalignant lesions of the cervix: evidence of a protective role for folate, riboflavin, thiamin, and vitamin B12 by Hernandez BY¹, McDuffie K, Wilkens LR, Kamemoto L, Goodman MT.(PubMed)
(b) A case control study of nutritional factors and cervical dysplasia by Liu T¹, Soong SJ, Wilson NP, Craig CB, Cole P, Macaluso M, Butterworth CE Jr.(PubMed)
(c) [Chemoprevention of cervical cancer--intervention study of cervical precancerous lesions by retinamide II and riboflavin].[Article in Chinese] byChen RD.(PubMed)
(d) Epidemiologic studies of vitamins and cancer of the lung, esophagus, and cervix by Ziegler RG.(PubMed)
(a) Cerical cancer (Amerrican cancer society)
(1) Nutritional and genetic inefficiencies in one-carbon metabolism and cervical cancer risk. by Ziegler RG¹, Weinstein SJ, Fears TR.(PubMed)
(2) Vitamin B6 status in patients with cancer of the uterine cervix by Ramaswamy PG, Natarajan R.(PubMed)
(3) Elevated serum homocysteine levels and increased risk of invasive cervical cancer in US women by Weinstein SJ¹, Ziegler RG, Selhub J, Fears TR, Strickler HD, Brinton LA, Hamman RF, Levine RS, Mallin K, Stolley PD.(PubMed)
(4) Association of methylenetetrahydrofolate reductase polymorphism C677T and dietary folate with the risk of cervical dysplasia by Goodman MT¹, McDuffie K, Hernandez B, Wilkens LR, Bertram CC, Killeen J, Le Marchand L, Selhub J, Murphy S, Donlon TA.(PubMed)
(5) Human papillomavirus persistence and nutrients involved in the methylation pathway among a cohort of young women by Sedjo RL¹, Inserra P, Abrahamsen M, Harris RB, Roe DJ, Baldwin S, Giuliano AR.(PubMed)

Almond bread slice

Contributed by 4 Ingredients by Kim McCosker and Rachael Bermingham (Atria Books)

 Make 15 slices
4 egg whites
1/2 cup sugar
1 cup oil purpose flour 1 cup sliced almonds
Preheat the oven to 350 degrees F. beat egg whites until stiff, then add sugar and bear for 1 minutes. Stir in a lined loaf pan and bake for 40 minutes. Re move loaf from oven but leave oven on. When cool enough to handle, thinly slice loaf and place slices on a baking sheet.
Return to oven for 10 minutes or until browned.



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Hot Chili Cheese Dip

From Quick and easy family favorites by Vickie and JoAnn

Be sure to know this hearty dip on your menu the next time family & friends are over to watch the big game..... it will be a hit.
1 lb. mild or spicy ground pork sausage, browned and drained
2 (103/4-oz. cans nacho cheese soup
15-oz. can chili with beans
141/2 oz. can tomatoes with chiles
16-oz. pkg. pasteurized process cheese spread, cubed
Combine all ingredients except cheese in a large saucepan over medium heat; cook until bubbly. Add cheese. Reduced heat; cook and stir until cheese is completely melted.
Make 6 to 7 cups.

David Wink
Gooseberry Patch



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Cervical cancer in Vitamin B2 Points of View

 Kyle J. Norton

 According to the American Cancer Society's, in 2014, 12,360 new cases of invasive cervical cancer will be diagnosed with the death of  4,020 patients. The risk of cervical cancer is higher in Hispanic women followed by African-Americans, Asians and Pacific Islanders, and whites(a).

Vitamin B2 also known as  Riboflavin, is a water-soluble, yellow-orange organic compound found abundantly in milk, meat, eggs, nuts, enriched flour, green vegetables, etc. The vitamin is essential for normal cellular growth and function and best known for converting energy from protein, fat, and carbohydrates during metabolism and its antioxidant effects in oxidation-reduction reactions.

Epidemiological studies, linking vitamin B2 in reduced risk and treatment of cervical cancer have been inclusive(a)(b)(c)(d). Suggestion of serum homocysteine was strongly and significantly predictive of invasive cervical cancer risk. In the study of cervical cancer risk factors through at-home interview and blood drawn at least 6 months after completion of cancer treatment from 51% and 68% of interviewed cases and controls, suggested that elevated serum homocysteine increased risk of cervical cancer are associated to the inadequacy of folate, B12 and/or B6, or genetic polymorphisms affecting one-carbon metabolism(1)(2). Other researchers indicated that deficiencies in dietary B-vitamin input and genetic polymorphisms for the enzymes in one-carbon metabolism are associated with a host of human health concerns,including cancer(3). Vitamin B2 deficiency may lead to with cervical cancer and precancerous lesions. Researchers at the the First Affiliated Hospital of Xinjiang Medical University, found that the inverse association  between tissue riboflavin levels and C20orf54 mRNA and protein expression in cervical squamous cell carcinoma (CSCC)(4), serum and tissues of vitamin B2 may be linked to the risk of the cervical cancer development. In the methylenetetrahydrofolate reductase (MTHFR) gene, the ¹University of Alabama at Birmingham, Birmingham showed that women who have the MTHFR polymorphism and low riboflavin status, were less likely to develop cervical intraepithelial neoplasia (CIN) 2 or 3, than women who was without the polymorphism and high riboflavin status(5). In the analysis of the cancer site, MTHFR C677T polymorphism interacted with folate and riboflavin in modulating cancer risk in a manner, depending to the types of cancer but  the effect on cervical cancer risk is not clear(6).

Taking altogether, Vitamin B2 deficiency and defection of methylenetetrahydrofolate reductase (MTHFR) gene may be associated to increased risk of cervical cancer, but further studies are necessary to validate its claims. At the mean time, please make sure you follow the guideline of the Institute of Medicine of the National Academies as  over doses for a prolong period may cause symptoms of skin rashes, hypersensitivity, high blood pressure etc.,



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Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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References
(a) Diet and premalignant lesions of the cervix: evidence of a protective role for folate, riboflavin, thiamin, and vitamin B12 by Hernandez BY¹, McDuffie K, Wilkens LR, Kamemoto L, Goodman MT.(PubMed)
(b) A case control study of nutritional factors and cervical dysplasia by Liu T¹, Soong SJ, Wilson NP, Craig CB, Cole P, Macaluso M, Butterworth CE Jr.(PubMed)
(c) [Chemoprevention of cervical cancer--intervention study of cervical precancerous lesions by retinamide II and riboflavin].[Article in Chinese] byChen RD.(PubMed)
(d) Epidemiologic studies of vitamins and cancer of the lung, esophagus, and cervix by Ziegler RG.(PubMed)
(1) Elevated serum homocysteine levels and increased risk of invasive cervical cancer in US women.

Weinstein SJ¹, Ziegler RG, Selhub J, Fears TR, Strickler HD, Brinton LA, Hamman RF, Levine RS, Mallin K, Stolley PD.(PubMed)

(2) Nutritional and genetic inefficiencies in one-carbon metabolism and cervical cancer risk by Ziegler RG¹, Weinstein SJ, Fears TR.(PubMed) 

(3) Mathematical Models of Cell Metabolism(Fred Hutchinson cancer research center)
(4) Association of the plasma and tissue riboflavin levels with C20orf54 expression in cervical lesions and its relationship to HPV16 infection by Aili A¹, Hasim A, Kelimu A, Guo X, Mamtimin B, Abudula A, Upur H.(PubMed)
(5) Protective association of MTHFR polymorphism on cervical intraepithelial neoplasia is modified by riboflavin status by Piyathilake CJ¹, Azrad M, Macaluso M, Johanning GL, Cornwell PE, Partridge EE, Heimburger DC.(PubMed)
(6) Interaction among folate, riboflavin, genotype, and cancer, with reference to colorectal and cervical cancer. by Powers HJ.(PubMed)  


 

Button mushroom and Cardiovascular disease (CVD)

By Kyle J. Norton

Scientists may have found one of the natural food used in many different cultures with a potential in reduced risk and protected against CVD.

Strong evidences through epidemiological studies suggested that regular consumption of fruits and vegetables is strongly associated with a reduced risk of cardiovascular disease (CVD)(7)(8)(9). Dietary fungi, such as, mushrooms, can protect against chronic disease by altering inflammatory environments through inhibition of cellular processes under pro-inflammatory conditions which are associated with CVD(2)(3).

According to Dr. Martin KR., ergothioneine (ERT), a novel antioxidant, presented in edible mushrooms, accumulated through diet was found effective in interrupted pro-inflammatory induction of adhesion molecule expression associated with atherogenesis(1).

Mushroom, a standard name of white button mushroom, the fleshy, spore-bearing fruiting body of a fungus produced above ground on soil or on its food source, contains several important nutrients including Thiamine (Vitamin B1), Riboflavin (Vitamin B2), Niacin (Vitamin B3), Pantothenic acid (Vitamin B5),  Calcium, Phosphorus, Potassium, Sodium, Selenium, Iron, Copper and Zinc which are necessary to maintain the growth, body functions as well as protected against chronic diseases.

Its antioxidants such as Astraodorol, Psilocybin, Lectin, adustin, ribonuclease, nicotine, etc. may also consist the magic power in reduced risk and treatment of vary types of cancer, including colon(4), breast and gastric cancers(5) through inhibition of cell cycle arrest, significant suppression of  cellular proliferation, in tested cancer cell lines.

These findings showed to support the notion of dietary mushrooms in protection of CVD, but multi canters and large sample size studies to identify the main ingredients comparable to current medicine used are necessary to improve its validation.

But, the study of University of Gdańsk, in the reviews and updates data on macro and trace elements and radionuclides in edible wild-grown and cultivated mushrooms suggested that the coexistence of
minerals of nutritional value collected from natural habitats, and co-occurrence with some hazardous elements including Cd, Pb, Hg, Ag, As, and radionuclides should be taken certain precautions(6).


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References
(1) The bioactive agent ergothioneine, a key component of dietary mushrooms, inhibits monocyte binding to endothelial cells characteristic of early cardiovascular disease by Martin KR.(PubMed)
(2) Both common and specialty mushrooms inhibit adhesion molecule expression and in vitro binding of monocytes to human aortic endothelial cells in a pro-inflammatory environment by Martin KR.(PubMed)
(3) Macro and trace mineral constituents and radionuclides in mushrooms: health benefits and risks. by Falandysz J¹, Borovička J.(PubMed)
(4) Intracellular trafficking and release of intact edible mushroom lectin from HT29 human colon cancer cells Lu-Gang Yu¹, David G. Fernig² an Jonathan M. Rhodes (The Febs Journal)
(5) Commonly consumed and specialty dietary mushrooms reduce cellular proliferation in MCF-7 human breast cancer cells by Martin KR¹, Brophy SK.(PubMed)
(6) Macro and trace mineral constituents and radionuclides in mushrooms: health benefits and risks. by Falandysz J¹, Borovička J.(PubMed)
(7) Fruit and vegetable consumption and all-cause, cancer and CVD mortality: analysis of Health Survey for England data by Oyebode O¹, Gordon-Dseagu V, Walker A, Mindell JS.(PubMed)
(8) Seasonal consumption of salad vegetables and fresh fruit in relation to the development of cardiovascular disease and cancer by Cox BD¹, Whichelow MJ, Prevost AT.(PubMed)
(9) Intakes of fruits, vegetables and carbohydrate and the risk of CVD by Joshipura KJ¹, Hung HC, Li TY, Hu FB, Rimm EB, Stampfer MJ, Colditz G, Willett WC.(PubMed)

Spiced chili nuts and seeds

 From Fresh and Easy Meals by Better Homes and Gardens

Pick your favorite nuts and seed for this snack recipe. Orange juice concentration spiked with piquant spices gives the mixture a burst of favor.

Prep. 10 minutes
Bake 15 minutes
Oven 300 degrees F
Make 16 (1/4 cup) serving

2 tsp. frozen orange juice concentrate thawed.
2 tsp. Worcestershire sauce
1 tsp. garlic powder
1 tsp. ground cumin
1 tsp. chili powder
1/2 tsp. cayenne pepper
1/4 tsp. salt
1/4 tsp. ground allspice
1.4 tsp. onion salt
2 cups unsalted peanuts, hazelnuts, and/or Brazil nuts
1 cup pecan halves
6 tsp. unsalted shelled sunflower seeds
2 tsp. sesame seeds
Non stick cooking tray

In a large bowl, combined orange juice concentrate, Worcestershire sauce, garlic powder, cumin, chili powder, cayenne pepper,salt, allspice, black pepper and onion salt. Stir in nuts and seeds; toss to coat.
Line a 15x10x1 inch baking pan with foil; slightly coat with nonstick cooking spray. Spread nuts and seed on foil. Bake in a300 degrees oven for 15 to 20 minutes or until toasted, stirring once. Cool. Store in an airtight container at room temperature for up to 1 week.

Nutrition facts per serving: 186Cal, 16 g total fat(2 g sat. fat), 0mg cholesterol, 59 sodium, 7 g carbo, 3 g fiber, 6 g pro.
daily value: 2% vitamin A, 6% vitamin C, 2% calcium, 5% iron.



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