Cirrhosis is defined as a condition of irreversible scarring liver as a
result of liver tissue by fibrosis due to final phase of chronic liver diseases
of that can lead to poor function of the liver and liver failure. According to
the statistics, Number of discharges with chronic liver disease or cirrhosis as
the first-listed diagnosis: 101,000 in 2009 and Deaths per 100,000 population:
10.3 in 2010(a). Hepatitis B infection cause of the disease is very prevalent in
South-East Asia.
Treatment of the complications of cirrhosis
A.2.1. Edema
A.2.1.1. In conventional medicine perspective
Diuretic is a type of medication used to elevates the rate of urination
to reduce swelling as a result of fluid retention, including
1. High ceiling loop diuretic
2 Thiazides
3 Carbonic anhydrase inhibitors
4 Potassium-sparing diuretics
5 Calcium-sparing diuretics
6 Osmotic diuretics
7. Low ceiling diuretics
Side effects are not limit to increased thirst, Irregular menstruation,
High blood sugar levels, blood sodium levels, Abnormal heart rhythm,
Weakness, Extreme tiredness / Fatigue, Dizziness, Light headedness, Skin
rash, Loss of appetite, etc.
A.2.1.2. In herbal medicine perspective
In the study to review these studies and identify which extracts promote diuresis
(which we assessed on terms of urine excreted and urinary sodium
excretion) and also to identify the research needs in this area, found that a number of species and genuses reporting diuretic
effects. Of these, the most promising, at the present time, are the
species Foeniculum vulgare, Fraxinus excelsior, Hibiscus sabdariffa,
Petroselinum sativum and Spergularia purpurea, and species from the
genuses Cucumis (Cucumis melo and Cucumis trigonus), Equisetum
(Equisetum bogotense, Equisetum fluviatile, Equisetum giganteum,
Equisetum hiemale var. affine and Equisetum myriochaetum), Lepidium
(Lepidium latifolium and Lepidium sativum), Phyllanthus (Phyllanthus
amarus, Phyllanthus corcovadensis and Phyllanthus sellowianus) and
Sambucus (Sambucus mexicana and Sambucus nigra)(87).
A.2.1.3. In traditional Chinese medicine perspective
In a clinical trial to evaluate the method of removing Heat and eliminating Dampness (RHED) with febrifugal and diuretic medicinal herbs in treating chronic glomerulonephritis (CGN) patients, found that
CGN patient's serum levels of lipid peroxide (LPO) increased, superoxide
dismutase (SOD) and trace elements such as Zn, Cu, Se dropped down.
After treatment with RHED the activity of LPO, SOD, catalase (CAT)
revealed significant improvement. Serum levels of Zn, Cu, Se increased(88).
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to General health http://kylejnorton.blogspot.ca/p/general-health.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(a) http://www.cdc.gov/nchs/fastats/liverdis.htm
(87) http://www.ncbi.nlm.nih.gov/pubmed/17804183
(88) http://www.ncbi.nlm.nih.gov/pubmed/8111197
Tuesday, 3 December 2013
Cirrhosis - Treatments of Medication causes of cirrhosis
Cirrhosis is defined as a condition of irreversible scarring liver as a
result of liver tissue by fibrosis due to final phase of chronic liver diseases
of that can lead to poor function of the liver and liver failure. According to
the statistics, Number of discharges with chronic liver disease or cirrhosis as
the first-listed diagnosis: 101,000 in 2009 and Deaths per 100,000 population:
10.3 in 2010(a). Hepatitis B infection cause of the disease is very prevalent in
South-East Asia.
Treatments
A. Treatments of cirrhosis depend not on the underline causes and stage of the diseases
Medication causes of cirrhosis
According to the study by the Seoul National University College of Medicine, anti-tuberculosis (TB) drug-induced liver injury (DILI) in patients with chronic liver disease including cirrhosis, but the drugs may be safely used in the patients with chronic liver disease including compensated cirrhosis if number of hepatotoxic drugs used is adjusted appropriately(85). In other study by University "Magna Græcia" of Catanzaro, there is a case of a male patient who developed severe drug-induced hepatotoxicity during the treatment with Cyproterone acetate (CPA). The case, presenting sub-acute hepatitis, was characterized by a rapid evolution of cirrhosis and a protracted activity during the period of a few months despite the treatment withdrawal and an apparent benefits of corticosteroids, suggesting their indication in life threatening cases(86). Please consult your doctor for replacement medication.
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to General health http://kylejnorton.blogspot.ca/p/general-health.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(a) http://www.cdc.gov/nchs/fastats/liverdis.htm
(85) http://www.ncbi.nlm.nih.gov/pubmed/20670648
Treatments
A. Treatments of cirrhosis depend not on the underline causes and stage of the diseases
Medication causes of cirrhosis
According to the study by the Seoul National University College of Medicine, anti-tuberculosis (TB) drug-induced liver injury (DILI) in patients with chronic liver disease including cirrhosis, but the drugs may be safely used in the patients with chronic liver disease including compensated cirrhosis if number of hepatotoxic drugs used is adjusted appropriately(85). In other study by University "Magna Græcia" of Catanzaro, there is a case of a male patient who developed severe drug-induced hepatotoxicity during the treatment with Cyproterone acetate (CPA). The case, presenting sub-acute hepatitis, was characterized by a rapid evolution of cirrhosis and a protracted activity during the period of a few months despite the treatment withdrawal and an apparent benefits of corticosteroids, suggesting their indication in life threatening cases(86). Please consult your doctor for replacement medication.
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to General health http://kylejnorton.blogspot.ca/p/general-health.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(a) http://www.cdc.gov/nchs/fastats/liverdis.htm
(85) http://www.ncbi.nlm.nih.gov/pubmed/20670648
Cirrhosis - Treatments of Hepatitis causes of cirrhosis
Cirrhosis is defined as a condition of irreversible scarring liver as a
result of liver tissue by fibrosis due to final phase of chronic liver diseases
of that can lead to poor function of the liver and liver failure. According to
the statistics, Number of discharges with chronic liver disease or cirrhosis as
the first-listed diagnosis: 101,000 in 2009 and Deaths per 100,000 population:
10.3 in 2010(a). Hepatitis B infection cause of the disease is very prevalent in
South-East Asia.
Treatments
A. Treatments of cirrhosis depend not on the underline causes and stage of the diseases
A.3. Hepatitis causes of cirrhosis
Hepatitis is characterized by the destruction of a number of liver cells and the presence of inflammatory cells in the liver tissue caused by excessive alcohol drinking, disorders of the gall bladder or pancreas, including medication side effects, and infections. There are many other infective agents that can cause inflammation of the liver, or hepatitis. However, the term is unfortunately commonly used to refer to a particular group of viruses such as Hepatitis A, B, and C.
A.3.1. In conventional medicine perspective(82)
1. Liver Detoxification
Strengthens the immune system with vitamins, nutritional supplements and herbs that we have been discussed lengthily in other articles.
2. Ozone therapy
Ozone oxidizes the cells of the body systemically. It stimulates enzymes and phagocytes of the white blood cells which chew up the viruses and the bacteria in the blood. It also activates alpha interferon, gamma interferon, interleukin II and tumor necrosis factor. It is effective in treating hepatitis B patients with high successful rate.
3. Lamivudine therapy
Combining vaccine therapy with lamivudine has improved therapeutic potential for chronic hepatitis B. It helps to strengthen the immune system fighting against the hepatitis B virus specially with patients with chronic HBV infection and active viral replication.
4. Interferon-alpha therapy
Chronic hepatitis B virus (HBV) infection is a serious health problem because of its worldwide distribution. There are over 350 million people in the world infected with chronic HBV, 75% of whom live in the Asia-Pacific region. Interferon-alfa and direct antiviral agents such as lamivudine and adefovir are effective in the therapy of chronic HBV infection but only with some success, particularly in perinatally infected patients, patients with lower ALT levels and those with negative chronic hepatitis B.
5. Pegylated interferon
Pegylated interferon may be considered the best choice of treatment for patients with chronic hepatitis B infection. This therapy has been shown to be superior to both conventional interferon as well as lamivudine in the treatment of both hepatitis B positive and negative chronic hepatitis B with successful rates of 35-45%.
A.3.2. In herbs medicine perspective(83)
1. Red clover
Rich in micro-nutrients it possesses activity against several bacteria. A good dietary supplement of vitamin A and Iron, it also contains B- complex, vitamins C,F, and P, some selenium, cobalt, nickel, manganese, sodium and is particularly rich in magnesium, calcium and copper.
2. Oregon grape root
The herb stimulates the action on the liver and is one of the best blood cleansers. Mild stimulant to the thyroid functions and aids in the assimilation of nutrients.
3. Echinacea
Echinacea is an immuno stimulant. Enhancing the body's resistance against both bacterial and viral infections it is probably the best detoxifying agent in Western Herbalism. It cleanses the blood and lymph systems, helps arrest pus formation and tissue putrefaction.
4. Sarsaparilla
Sarsaparilla purifies the urino-genital tract, dispelling all infection and inflammation. It's purifying action extends to the nervous system and is therefore useful in many nervous disorders. Sarsaparilla's diaphoretic and blood cleansing action is useful for rheumatic inflammation.
5. Licorice root
Licorice root is a natural anti-inflammatory agent. It helps to increase the secretion of digestive enzymes and bile and is widely regarded as the supreme liver tonic.
6. Burdock
It clears congestion, reduces swelling and dispels toxins via the skin, kidneys and bowel. It is a nutritive and rejuvenatory tonic . Historically it has been used to support the action of the kidneys in urinary tract infections.
7. Dandelion
Dandelion cleanses the liver, kidneys, lymph and bowel and is ideal for toxic blood conditions. It increases the secretion of digestive enzymes and bile and is widely regarded as the supreme liver tonic.
A.3.3 In Traditional Chinese medicine perspective(84)
1. Natural schisandra,
Schisandradra contains essential oils, acids and lignans that help to regenerate liver tissue caused by excessive drinking of alcohol and hepatitis virus.
2. Milk thistle,
consists of three components silybin, silydianin, and silychristin that help to reverse liver damage from alcohol, liver injure in result of chronic hepatitis and sloe the advance of cirrhosis.
3. Dan shen Danshen
is frequently used for these problems in combination with other herbs in treating liver diseases such as cirrhosis, fibrosis, and chronic hepatitis B.
4. Lycii
Lycii contains high amount of beta-carotene that helps to nourish and tonify liver and kidney.
5. Chinese licorice
Licorice contains a compound called glycyrrhizin and has a long history of medicinal use in both Eastern and Western systems of medicine in treating infections caused by viruses, such as hepatitis.
6. Astragalus
Astragalus is used conbination with other Chinese herbs are thought to possess properties in treating cancer, viral infection and immune system disorder. Astragalus is an ingredient in
7. Baikal scullcap
Baikal scullcap contains a chemical of baikalin that helps liver to detoxification and fight against liver infection.
8. Gynostemma,
Gynostemma pentaphylla
This herb has been used over thousand years in Chinese history in treating a variety of diseases such as high blood fat, heart disease, strengthen immune system as well as hepatitis.
9. American ginseng
American ginseng contain the ginsenosides ingredient that is effective in preventing GalN-induced liver cell damage and is a useful agent for chemoprevention of cancer or inflammatory diseases such as liver infection by hepatitis virus
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to General health http://kylejnorton.blogspot.ca/p/general-health.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(a) http://www.cdc.gov/nchs/fastats/liverdis.htm
(82) http://medicaladvisorjournals.blogspot.ca/2012/01/hepatitis-hepatitis-treatments.html
(83) http://medicaladvisorjournals.blogspot.ca/2012/01/hepatitis-how-to-prevent-and-treat.html
(84) http://medicaladvisorjournals.blogspot.ca/2012/01/hepatitis-how-to-prevent-hepatitis-with_11.html
Treatments
A. Treatments of cirrhosis depend not on the underline causes and stage of the diseases
A.3. Hepatitis causes of cirrhosis
Hepatitis is characterized by the destruction of a number of liver cells and the presence of inflammatory cells in the liver tissue caused by excessive alcohol drinking, disorders of the gall bladder or pancreas, including medication side effects, and infections. There are many other infective agents that can cause inflammation of the liver, or hepatitis. However, the term is unfortunately commonly used to refer to a particular group of viruses such as Hepatitis A, B, and C.
A.3.1. In conventional medicine perspective(82)
1. Liver Detoxification
Strengthens the immune system with vitamins, nutritional supplements and herbs that we have been discussed lengthily in other articles.
2. Ozone therapy
Ozone oxidizes the cells of the body systemically. It stimulates enzymes and phagocytes of the white blood cells which chew up the viruses and the bacteria in the blood. It also activates alpha interferon, gamma interferon, interleukin II and tumor necrosis factor. It is effective in treating hepatitis B patients with high successful rate.
3. Lamivudine therapy
Combining vaccine therapy with lamivudine has improved therapeutic potential for chronic hepatitis B. It helps to strengthen the immune system fighting against the hepatitis B virus specially with patients with chronic HBV infection and active viral replication.
4. Interferon-alpha therapy
Chronic hepatitis B virus (HBV) infection is a serious health problem because of its worldwide distribution. There are over 350 million people in the world infected with chronic HBV, 75% of whom live in the Asia-Pacific region. Interferon-alfa and direct antiviral agents such as lamivudine and adefovir are effective in the therapy of chronic HBV infection but only with some success, particularly in perinatally infected patients, patients with lower ALT levels and those with negative chronic hepatitis B.
5. Pegylated interferon
Pegylated interferon may be considered the best choice of treatment for patients with chronic hepatitis B infection. This therapy has been shown to be superior to both conventional interferon as well as lamivudine in the treatment of both hepatitis B positive and negative chronic hepatitis B with successful rates of 35-45%.
A.3.2. In herbs medicine perspective(83)
1. Red clover
Rich in micro-nutrients it possesses activity against several bacteria. A good dietary supplement of vitamin A and Iron, it also contains B- complex, vitamins C,F, and P, some selenium, cobalt, nickel, manganese, sodium and is particularly rich in magnesium, calcium and copper.
2. Oregon grape root
The herb stimulates the action on the liver and is one of the best blood cleansers. Mild stimulant to the thyroid functions and aids in the assimilation of nutrients.
3. Echinacea
Echinacea is an immuno stimulant. Enhancing the body's resistance against both bacterial and viral infections it is probably the best detoxifying agent in Western Herbalism. It cleanses the blood and lymph systems, helps arrest pus formation and tissue putrefaction.
4. Sarsaparilla
Sarsaparilla purifies the urino-genital tract, dispelling all infection and inflammation. It's purifying action extends to the nervous system and is therefore useful in many nervous disorders. Sarsaparilla's diaphoretic and blood cleansing action is useful for rheumatic inflammation.
5. Licorice root
Licorice root is a natural anti-inflammatory agent. It helps to increase the secretion of digestive enzymes and bile and is widely regarded as the supreme liver tonic.
6. Burdock
It clears congestion, reduces swelling and dispels toxins via the skin, kidneys and bowel. It is a nutritive and rejuvenatory tonic . Historically it has been used to support the action of the kidneys in urinary tract infections.
7. Dandelion
Dandelion cleanses the liver, kidneys, lymph and bowel and is ideal for toxic blood conditions. It increases the secretion of digestive enzymes and bile and is widely regarded as the supreme liver tonic.
A.3.3 In Traditional Chinese medicine perspective(84)
1. Natural schisandra,
Schisandradra contains essential oils, acids and lignans that help to regenerate liver tissue caused by excessive drinking of alcohol and hepatitis virus.
2. Milk thistle,
consists of three components silybin, silydianin, and silychristin that help to reverse liver damage from alcohol, liver injure in result of chronic hepatitis and sloe the advance of cirrhosis.
3. Dan shen Danshen
is frequently used for these problems in combination with other herbs in treating liver diseases such as cirrhosis, fibrosis, and chronic hepatitis B.
4. Lycii
Lycii contains high amount of beta-carotene that helps to nourish and tonify liver and kidney.
5. Chinese licorice
Licorice contains a compound called glycyrrhizin and has a long history of medicinal use in both Eastern and Western systems of medicine in treating infections caused by viruses, such as hepatitis.
6. Astragalus
Astragalus is used conbination with other Chinese herbs are thought to possess properties in treating cancer, viral infection and immune system disorder. Astragalus is an ingredient in
7. Baikal scullcap
Baikal scullcap contains a chemical of baikalin that helps liver to detoxification and fight against liver infection.
8. Gynostemma,
Gynostemma pentaphylla
This herb has been used over thousand years in Chinese history in treating a variety of diseases such as high blood fat, heart disease, strengthen immune system as well as hepatitis.
9. American ginseng
American ginseng contain the ginsenosides ingredient that is effective in preventing GalN-induced liver cell damage and is a useful agent for chemoprevention of cancer or inflammatory diseases such as liver infection by hepatitis virus
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to General health http://kylejnorton.blogspot.ca/p/general-health.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(a) http://www.cdc.gov/nchs/fastats/liverdis.htm
(82) http://medicaladvisorjournals.blogspot.ca/2012/01/hepatitis-hepatitis-treatments.html
(83) http://medicaladvisorjournals.blogspot.ca/2012/01/hepatitis-how-to-prevent-and-treat.html
(84) http://medicaladvisorjournals.blogspot.ca/2012/01/hepatitis-how-to-prevent-hepatitis-with_11.html
Cirrhosis Treatments of Obesity and Fatty liver Causes of Cirrhosis
Cirrhosis is defined as a condition of irreversible scarring liver as a
result of liver tissue by fibrosis due to final phase of chronic liver diseases
of that can lead to poor function of the liver and liver failure. According to
the statistics, Number of discharges with chronic liver disease or cirrhosis as
the first-listed diagnosis: 101,000 in 2009 and Deaths per 100,000 population:
10.3 in 2010(a). Hepatitis B infection cause of the disease is very prevalent in
South-East Asia.
Treatments
A. Treatments of cirrhosis depend not on the underline causes and stage of the diseases
Obesity and Fatty liver
The prevalence of overweight and obesity are increasing in World wide, especially in the Emerging world, as a result of recently economic prosperity.
Obesity is defined as a medical condition of excess body fat accumulated overtime. Overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. In US, 68% of population are either overweight or obese. According to the study by Department of Pediatrics, Nanjing Maternity and Child Health Care Hospital, for age-specific subgroup analyses, both overweight and obesity increased more rapidly in the toddler stage than in other developmental stages. Toddlers and urban boys were at particularly high risk; the prevalence in these groups increased more rapidly than in their counterparts(73a)).
The Obesity Society and the American Society of Hypertension agreed to jointly sponsor a position paper on obesity-related hypertension to be published jointly in the journals of each society(2). Other researchers suggested that in light of the worldwide epidemic of obesity, and in recognition of hypertension as a major factor in the cardiovascular morbidity and mortality associated with obesity(73b).
Recent study showed that evidence has emerged for an association between genetic variability at the APOA5 locus and increased risk of obesity and metabolic syndrome(73c).
Fatty liver disease is defined as a condition of accumulation of fat in the liver, including people who drink little or no alcohol (Non alcohol fatty disease) or who are excessive alcohol drinking (Alcohol fatty liver disease). The disease can even occur after a short period of heavy drinking (acute alcoholic liver disease). More than 15 million people in the U.S. either abuse or overuse alcohol with fatty liver diseases with fat makes up 5-10 percent of liver weight.
Non-alcoholic fatty liver disease (NAFLD) encompasses a wide spectrum of clinical conditions, actually representing an emerging disease of great clinical interest(73).
There is no standard treatment in conventional medicine. If you are obese, you are advised to lose weight. If excessive drinking alcohol is the cause, you are advised to stop drinking.
Some researchers suggested that Vitamin E plus C combination treatment is a safe, inexpensive and effective treatment option in patients with fatty liver disease, with results comparable to those obtained with ursodeoxycholic acid(74). But some researchers suggested that Neither vitamin E nor metformin was superior to placebo in attaining the primary outcome of sustained reduction in ALT level in patients with pediatric NAFLD(75).
In traditional Chinese medicine, fatty liver is associated closely to obesity, as a result of over intake of "bad" fat and excessive alcohol drinking. Even though fatty liver is a result of too much fat, but trying to eliminate all fats from the diet won't help to prevent or relieve the disease as malnutrition can also trigger fatty liver as fat and protein stored elsewhere in the body move to the liver for storage and conversion to energy as needed. That's why some women who eat almost nothing but vegetables can also develop fatty liver(76).
Many traditional Chinese medicine practitioners believe, no way that one can lose weight if fatty liver diseases are not cured. Syndromes of fatty liver could be typed into 4 TCM types of the asthenia Pi-Shen with Gan-stagnation type, the asthenia Pi-Shen type, the asthenia Pi with phlegm-heat type and the unclassified type. Among them the asthenia Pi-Shen with Gan-stagnation type was the commonest one, which accounted to 62.32%(77).
Dr. Liu T, and the research team at the Shanghai University of Traditional Chinese Medicine, in the study to explore the pathogenesis of nonalcoholic fatty liver (NAFL) in traditional Chinese medicine (TCM) by comparing the therapeutic efficacy of methods for fortifying the spleen and replenishing qi, warming yang and fortifying the spleen and warming yang to move water, showed that body weight, liver and epididymal fat indexes and liver TAG level of rats all significantly increased in the model group as compared with the normal group (P<0.05). Hepatic fatty infiltration, TAG concentration and the levels of serum TAG and ALT were significantly decreased in the LGZG and SZ groups when compared to those in the model group (P<0.05). Method of warming yang or moving water can promote the lipid metabolism. It may be an effective strategy in preventing and treating NAFL by treating with warming yang and moving water together(978
Other studies showed that Zhi Zi has a very strong inhibitory action on lipidosis and inflammatory injury in the rat model of NAFLD. This mechanism may possibly be related to the inhibition of the free fatty acid metabolism pathway(79).
In the study to investigate the effect of Cigu Xiaozhi pills on expression of tumor necrosis factor alpha (TNF-alpha) in rat with nonalcoholic steatoheptatitis (NASH), found that Cigu Xiaozhi pills can effectively treat experimental nonalcoholic steatohepatitis in rats, and its mechanism may be associated with ameliorating hepatocellular steatosis, removing the free radicals and enhancing the capability of anti-oxidation and anti-inflammatory(80).
Most people with fatty liver disease are experience no symptoms at all, but Fatty liver disease is associated with high blood pressure, heart disease and diabetes can, in time, cause life threatening cirrhosis of the liver. According to the article By Donald Norfolk, "Today, as a direct effect of the obesity plague, it's reckoned that one in five British adults is now suffering from fatty liver disease, unconnected with virus infections or heavy drinking. This malady, known medically as steatosis, is believed to affect 90 per cent of morbidly obese patients, in whom it may remain totally symptomless for many years"(81).
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to General health http://kylejnorton.blogspot.ca/p/general-health.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(a) http://www.cdc.gov/nchs/fastats/liverdis.htm
(73a) http://www.ncbi.nlm.nih.gov/pubmed/23284829
(73b) http://www.ncbi.nlm.nih.gov/pubmed/23282121
(73c) http://www.ncbi.nlm.nih.gov/pubmed/23279260
(73) http://www.ncbi.nlm.nih.gov/pubmed/23278163
(74) http://www.ncbi.nlm.nih.gov/pubmed/16245220
(75) http://www.ncbi.nlm.nih.gov/pubmed/21521847
(76) http://www.ncbi.nlm.nih.gov/pubmed/15768875
(77) http://live.shanghaidaily.com/column_detail.asp?type=column&id=718
(78) http://www.ncbi.nlm.nih.gov/pubmed/23073195
(79) http://www.ncbi.nlm.nih.gov/pubmed/22594108
(80) http://www.ncbi.nlm.nih.gov/pubmed/20707200
(81) http://ezinearticles.com/?Fatty-Livers:-A-Silent-Cause-of-Premature-Death&id=7065449
Treatments
A. Treatments of cirrhosis depend not on the underline causes and stage of the diseases
Obesity and Fatty liver
The prevalence of overweight and obesity are increasing in World wide, especially in the Emerging world, as a result of recently economic prosperity.
Obesity is defined as a medical condition of excess body fat accumulated overtime. Overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. In US, 68% of population are either overweight or obese. According to the study by Department of Pediatrics, Nanjing Maternity and Child Health Care Hospital, for age-specific subgroup analyses, both overweight and obesity increased more rapidly in the toddler stage than in other developmental stages. Toddlers and urban boys were at particularly high risk; the prevalence in these groups increased more rapidly than in their counterparts(73a)).
The Obesity Society and the American Society of Hypertension agreed to jointly sponsor a position paper on obesity-related hypertension to be published jointly in the journals of each society(2). Other researchers suggested that in light of the worldwide epidemic of obesity, and in recognition of hypertension as a major factor in the cardiovascular morbidity and mortality associated with obesity(73b).
Recent study showed that evidence has emerged for an association between genetic variability at the APOA5 locus and increased risk of obesity and metabolic syndrome(73c).
Fatty liver disease is defined as a condition of accumulation of fat in the liver, including people who drink little or no alcohol (Non alcohol fatty disease) or who are excessive alcohol drinking (Alcohol fatty liver disease). The disease can even occur after a short period of heavy drinking (acute alcoholic liver disease). More than 15 million people in the U.S. either abuse or overuse alcohol with fatty liver diseases with fat makes up 5-10 percent of liver weight.
Non-alcoholic fatty liver disease (NAFLD) encompasses a wide spectrum of clinical conditions, actually representing an emerging disease of great clinical interest(73).
There is no standard treatment in conventional medicine. If you are obese, you are advised to lose weight. If excessive drinking alcohol is the cause, you are advised to stop drinking.
Some researchers suggested that Vitamin E plus C combination treatment is a safe, inexpensive and effective treatment option in patients with fatty liver disease, with results comparable to those obtained with ursodeoxycholic acid(74). But some researchers suggested that Neither vitamin E nor metformin was superior to placebo in attaining the primary outcome of sustained reduction in ALT level in patients with pediatric NAFLD(75).
In traditional Chinese medicine, fatty liver is associated closely to obesity, as a result of over intake of "bad" fat and excessive alcohol drinking. Even though fatty liver is a result of too much fat, but trying to eliminate all fats from the diet won't help to prevent or relieve the disease as malnutrition can also trigger fatty liver as fat and protein stored elsewhere in the body move to the liver for storage and conversion to energy as needed. That's why some women who eat almost nothing but vegetables can also develop fatty liver(76).
Many traditional Chinese medicine practitioners believe, no way that one can lose weight if fatty liver diseases are not cured. Syndromes of fatty liver could be typed into 4 TCM types of the asthenia Pi-Shen with Gan-stagnation type, the asthenia Pi-Shen type, the asthenia Pi with phlegm-heat type and the unclassified type. Among them the asthenia Pi-Shen with Gan-stagnation type was the commonest one, which accounted to 62.32%(77).
Dr. Liu T, and the research team at the Shanghai University of Traditional Chinese Medicine, in the study to explore the pathogenesis of nonalcoholic fatty liver (NAFL) in traditional Chinese medicine (TCM) by comparing the therapeutic efficacy of methods for fortifying the spleen and replenishing qi, warming yang and fortifying the spleen and warming yang to move water, showed that body weight, liver and epididymal fat indexes and liver TAG level of rats all significantly increased in the model group as compared with the normal group (P<0.05). Hepatic fatty infiltration, TAG concentration and the levels of serum TAG and ALT were significantly decreased in the LGZG and SZ groups when compared to those in the model group (P<0.05). Method of warming yang or moving water can promote the lipid metabolism. It may be an effective strategy in preventing and treating NAFL by treating with warming yang and moving water together(978
Other studies showed that Zhi Zi has a very strong inhibitory action on lipidosis and inflammatory injury in the rat model of NAFLD. This mechanism may possibly be related to the inhibition of the free fatty acid metabolism pathway(79).
In the study to investigate the effect of Cigu Xiaozhi pills on expression of tumor necrosis factor alpha (TNF-alpha) in rat with nonalcoholic steatoheptatitis (NASH), found that Cigu Xiaozhi pills can effectively treat experimental nonalcoholic steatohepatitis in rats, and its mechanism may be associated with ameliorating hepatocellular steatosis, removing the free radicals and enhancing the capability of anti-oxidation and anti-inflammatory(80).
Most people with fatty liver disease are experience no symptoms at all, but Fatty liver disease is associated with high blood pressure, heart disease and diabetes can, in time, cause life threatening cirrhosis of the liver. According to the article By Donald Norfolk, "Today, as a direct effect of the obesity plague, it's reckoned that one in five British adults is now suffering from fatty liver disease, unconnected with virus infections or heavy drinking. This malady, known medically as steatosis, is believed to affect 90 per cent of morbidly obese patients, in whom it may remain totally symptomless for many years"(81).
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to General health http://kylejnorton.blogspot.ca/p/general-health.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(a) http://www.cdc.gov/nchs/fastats/liverdis.htm
(73a) http://www.ncbi.nlm.nih.gov/pubmed/23284829
(73b) http://www.ncbi.nlm.nih.gov/pubmed/23282121
(73c) http://www.ncbi.nlm.nih.gov/pubmed/23279260
(73) http://www.ncbi.nlm.nih.gov/pubmed/23278163
(74) http://www.ncbi.nlm.nih.gov/pubmed/16245220
(75) http://www.ncbi.nlm.nih.gov/pubmed/21521847
(76) http://www.ncbi.nlm.nih.gov/pubmed/15768875
(77) http://live.shanghaidaily.com/column_detail.asp?type=column&id=718
(78) http://www.ncbi.nlm.nih.gov/pubmed/23073195
(79) http://www.ncbi.nlm.nih.gov/pubmed/22594108
(80) http://www.ncbi.nlm.nih.gov/pubmed/20707200
(81) http://ezinearticles.com/?Fatty-Livers:-A-Silent-Cause-of-Premature-Death&id=7065449
Cirrhosis - Treatments of Alcohol causes of Cirrhosis
Cirrhosis is defined as a condition of irreversible scarring liver as a
result of liver tissue by fibrosis due to final phase of chronic liver diseases
of that can lead to poor function of the liver and liver failure. According to
the statistics, Number of discharges with chronic liver disease or cirrhosis as
the first-listed diagnosis: 101,000 in 2009 and Deaths per 100,000 population:
10.3 in 2010(a). Hepatitis B infection cause of the disease is very prevalent in
South-East Asia.
Treatments
A. Treatments of cirrhosis depend not on the underline causes and stage of the diseases
A.1. Alcohol causes of cirrhosis
A.1.2. In conventional medicine perspective
If the the disease is caused by excessive alcohol drinking, patients will be asked to stop drinking. with help from the professional teams and certain medication. The long-term management of alcoholic liver disease stresses the following(67).
(1) Abstinence of alcohol (Grade 1A), with referral to an alcoholic rehabilitation program;
(2) Adequate nutritional support (Grade 1B), emphasizing multiple feedings and a referral to a nutritionist; (3) Routine screening in alcoholic cirrhosis to prevent complications;
(4) Timely referral to a liver transplant program for those with decompensated cirrhosis;
(5) Avoid pharmacologic therapies, as these medications have shown no benefit.
But according to the study by the Catholic University of Rome, in the intervention to achieve alcohol abstinence represents the most effective treatment for alcohol-dependent patients with liver cirrhosis by investigating the effectiveness and safety of Baclofen, is a GABA(B) receptor agonist in achieving and maintaining alcohol abstinence in patients with liver cirrhosis, showed that baclofen is effective at promoting alcohol abstinence in alcohol-dependent patients with liver cirrhosis. The drug is well tolerated and could have an important role in treatment of these individuals(68).
A.1.2. In herbal medicine perspective
1. Kudzu (Pueraria lobata) and St. John's Wort
In the study to summarizes the findings of the effects on alcohol intake in alcohol-preferring rats of extracts or purified compounds from two of the most promising herbs: kudzu (Pueraria lobata) and St. John's Wort (Hypericum perforatum), a symposium presented at the 2002 RSA meeting in San Francisco. found that
(1) Introduction to the symposium, by David Y. W. Lee and David H. Overstreet; (2) Effects of daidzin on alcohol intake-search for mechanisms of action, by Wing-Ming Keung; (3) Long-term suppressive effects of puerarin on alcohol drinking in rats, by David Overstreet and David Y. W. Lee; (4) St. John's Wort extract reduces alcohol intake in FH and P rats, by Amir Rezvani and David Overstreet; and (5) extracts reduce alcohol intake in Marchigian Sardinian alcohol-preferring rats, by Maurizio Massi(69).
2. Pueraria lobata, Tabernanthe iboga, Panax ginseng, Salvia miltiorrhiza and Hypericum perforatum
In the study to review the most relevant experimental data on the reducing effect of some medicinal herbs on voluntary alcohol intake in animal models of alcoholism, showed that Pueraria lobata, Tabernanthe iboga, Panax ginseng, Salvia miltiorrhiza and Hypericum perforatum proved to be effective in decreasing alcohol consumption. Reduction of alcohol absorption from the gastrointestinal system appears to be a common feature among most of the above plants(70).
3. Other herbs
According to the study by, A number of medicinal plants and pure natural compounds are reported to have preventive and therapeutic effects on alcoholism and alcohol dependency, but their constituents, efficacy and mechanism of action are mostly unknown so far. Recently, kudzu [Pueraria lobata (Willd.) Ohwi], St. John's wort (Hypericum perforatum L.), danshen (Salvia miltiorrhiza Bge.), ginseng (Panax ginseng C.A. Mey.), Japanese raisin tree (Hovenia dulcis Thunb.), ibogaine (Tabernanthe iboga H. Bn.), evening primrose (Oenothera biennis L.), prickly pear fruit (Opuntia ficus indica (L.) Mill.), purple passionflower (Passiflora incarnata L.), thyme (Thymus vulgaris L.), fenugreek seed (Trigonella foenum-graecum L.), ginger (Zingiber officinale Roscoe) and many others drew the attention of researchers. Can, therefore, drugs of natural origin be helpful in the treatment of alcoholism or in decreasing alcohol consumption?(71)
A.1.3. In TCM medicine perspective
Alcohol has long been used as a daily beverage in China and around the world. It is a medicinal substance with various biological activities. According to study by Peking University, in the summarized clinical and primary studies concerning various remedies of TCM for alcohol abuse, including herbal components (such as Kudzu/Pueraria Lobata, Pediculus melo, Hypericumpperforatum L.), decoctions and acupuncture(72).
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to General health http://kylejnorton.blogspot.ca/p/general-health.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
Sources
(a) http://www.cdc.gov/nchs/fastats/liverdis.htm
(67) http://www.ncbi.nlm.nih.gov/pubmed/23101981
(68) http://www.ncbi.nlm.nih.gov/pubmed/18068515
(69) http://www.ncbi.nlm.nih.gov/pubmed/12605067
(70) http://www.ncbi.nlm.nih.gov/pubmed/10930711
(71) http://www.ncbi.nlm.nih.gov/pubmed/22474979
(72) http://www.ncbi.nlm.nih.gov/pubmed/21213394
Treatments
A. Treatments of cirrhosis depend not on the underline causes and stage of the diseases
A.1. Alcohol causes of cirrhosis
A.1.2. In conventional medicine perspective
If the the disease is caused by excessive alcohol drinking, patients will be asked to stop drinking. with help from the professional teams and certain medication. The long-term management of alcoholic liver disease stresses the following(67).
(1) Abstinence of alcohol (Grade 1A), with referral to an alcoholic rehabilitation program;
(2) Adequate nutritional support (Grade 1B), emphasizing multiple feedings and a referral to a nutritionist; (3) Routine screening in alcoholic cirrhosis to prevent complications;
(4) Timely referral to a liver transplant program for those with decompensated cirrhosis;
(5) Avoid pharmacologic therapies, as these medications have shown no benefit.
But according to the study by the Catholic University of Rome, in the intervention to achieve alcohol abstinence represents the most effective treatment for alcohol-dependent patients with liver cirrhosis by investigating the effectiveness and safety of Baclofen, is a GABA(B) receptor agonist in achieving and maintaining alcohol abstinence in patients with liver cirrhosis, showed that baclofen is effective at promoting alcohol abstinence in alcohol-dependent patients with liver cirrhosis. The drug is well tolerated and could have an important role in treatment of these individuals(68).
A.1.2. In herbal medicine perspective
1. Kudzu (Pueraria lobata) and St. John's Wort
In the study to summarizes the findings of the effects on alcohol intake in alcohol-preferring rats of extracts or purified compounds from two of the most promising herbs: kudzu (Pueraria lobata) and St. John's Wort (Hypericum perforatum), a symposium presented at the 2002 RSA meeting in San Francisco. found that
(1) Introduction to the symposium, by David Y. W. Lee and David H. Overstreet; (2) Effects of daidzin on alcohol intake-search for mechanisms of action, by Wing-Ming Keung; (3) Long-term suppressive effects of puerarin on alcohol drinking in rats, by David Overstreet and David Y. W. Lee; (4) St. John's Wort extract reduces alcohol intake in FH and P rats, by Amir Rezvani and David Overstreet; and (5) extracts reduce alcohol intake in Marchigian Sardinian alcohol-preferring rats, by Maurizio Massi(69).
2. Pueraria lobata, Tabernanthe iboga, Panax ginseng, Salvia miltiorrhiza and Hypericum perforatum
In the study to review the most relevant experimental data on the reducing effect of some medicinal herbs on voluntary alcohol intake in animal models of alcoholism, showed that Pueraria lobata, Tabernanthe iboga, Panax ginseng, Salvia miltiorrhiza and Hypericum perforatum proved to be effective in decreasing alcohol consumption. Reduction of alcohol absorption from the gastrointestinal system appears to be a common feature among most of the above plants(70).
3. Other herbs
According to the study by, A number of medicinal plants and pure natural compounds are reported to have preventive and therapeutic effects on alcoholism and alcohol dependency, but their constituents, efficacy and mechanism of action are mostly unknown so far. Recently, kudzu [Pueraria lobata (Willd.) Ohwi], St. John's wort (Hypericum perforatum L.), danshen (Salvia miltiorrhiza Bge.), ginseng (Panax ginseng C.A. Mey.), Japanese raisin tree (Hovenia dulcis Thunb.), ibogaine (Tabernanthe iboga H. Bn.), evening primrose (Oenothera biennis L.), prickly pear fruit (Opuntia ficus indica (L.) Mill.), purple passionflower (Passiflora incarnata L.), thyme (Thymus vulgaris L.), fenugreek seed (Trigonella foenum-graecum L.), ginger (Zingiber officinale Roscoe) and many others drew the attention of researchers. Can, therefore, drugs of natural origin be helpful in the treatment of alcoholism or in decreasing alcohol consumption?(71)
A.1.3. In TCM medicine perspective
Alcohol has long been used as a daily beverage in China and around the world. It is a medicinal substance with various biological activities. According to study by Peking University, in the summarized clinical and primary studies concerning various remedies of TCM for alcohol abuse, including herbal components (such as Kudzu/Pueraria Lobata, Pediculus melo, Hypericumpperforatum L.), decoctions and acupuncture(72).
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to General health http://kylejnorton.blogspot.ca/p/general-health.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
Sources
(a) http://www.cdc.gov/nchs/fastats/liverdis.htm
(67) http://www.ncbi.nlm.nih.gov/pubmed/23101981
(68) http://www.ncbi.nlm.nih.gov/pubmed/18068515
(69) http://www.ncbi.nlm.nih.gov/pubmed/12605067
(70) http://www.ncbi.nlm.nih.gov/pubmed/10930711
(71) http://www.ncbi.nlm.nih.gov/pubmed/22474979
(72) http://www.ncbi.nlm.nih.gov/pubmed/21213394
Cirrhosis Treatments of Alcohol causes of Cirrhosis
Cirrhosis is defined as a condition of irreversible scarring liver as a
result of liver tissue by fibrosis due to final phase of chronic liver diseases
of that can lead to poor function of the liver and liver failure. According to
the statistics, Number of discharges with chronic liver disease or cirrhosis as
the first-listed diagnosis: 101,000 in 2009 and Deaths per 100,000 population:
10.3 in 2010(a). Hepatitis B infection cause of the disease is very prevalent in
South-East Asia.
Treatments
A. Treatments of cirrhosis depend not on the underline causes and stage of the diseases
A.1. Alcohol causes of cirrhosis
A.1.2. In conventional medicine perspective
If the the disease is caused by excessive alcohol drinking, patients will be asked to stop drinking. with help from the professional teams and certain medication. The long-term management of alcoholic liver disease stresses the following(67).
(1) Abstinence of alcohol (Grade 1A), with referral to an alcoholic rehabilitation program;
(2) Adequate nutritional support (Grade 1B), emphasizing multiple feedings and a referral to a nutritionist; (3) Routine screening in alcoholic cirrhosis to prevent complications;
(4) Timely referral to a liver transplant program for those with decompensated cirrhosis;
(5) Avoid pharmacologic therapies, as these medications have shown no benefit.
But according to the study by the Catholic University of Rome, in the intervention to achieve alcohol abstinence represents the most effective treatment for alcohol-dependent patients with liver cirrhosis by investigating the effectiveness and safety of Baclofen, is a GABA(B) receptor agonist in achieving and maintaining alcohol abstinence in patients with liver cirrhosis, showed that baclofen is effective at promoting alcohol abstinence in alcohol-dependent patients with liver cirrhosis. The drug is well tolerated and could have an important role in treatment of these individuals(68).
A.1.2. In herbal medicine perspective
1. Kudzu (Pueraria lobata) and St. John's Wort
In the study to summarizes the findings of the effects on alcohol intake in alcohol-preferring rats of extracts or purified compounds from two of the most promising herbs: kudzu (Pueraria lobata) and St. John's Wort (Hypericum perforatum), a symposium presented at the 2002 RSA meeting in San Francisco. found that
(1) Introduction to the symposium, by David Y. W. Lee and David H. Overstreet; (2) Effects of daidzin on alcohol intake-search for mechanisms of action, by Wing-Ming Keung; (3) Long-term suppressive effects of puerarin on alcohol drinking in rats, by David Overstreet and David Y. W. Lee; (4) St. John's Wort extract reduces alcohol intake in FH and P rats, by Amir Rezvani and David Overstreet; and (5) extracts reduce alcohol intake in Marchigian Sardinian alcohol-preferring rats, by Maurizio Massi(69).
2. Pueraria lobata, Tabernanthe iboga, Panax ginseng, Salvia miltiorrhiza and Hypericum perforatum
In the study to review the most relevant experimental data on the reducing effect of some medicinal herbs on voluntary alcohol intake in animal models of alcoholism, showed that Pueraria lobata, Tabernanthe iboga, Panax ginseng, Salvia miltiorrhiza and Hypericum perforatum proved to be effective in decreasing alcohol consumption. Reduction of alcohol absorption from the gastrointestinal system appears to be a common feature among most of the above plants(70).
3. Other herbs
According to the study by, A number of medicinal plants and pure natural compounds are reported to have preventive and therapeutic effects on alcoholism and alcohol dependency, but their constituents, efficacy and mechanism of action are mostly unknown so far. Recently, kudzu [Pueraria lobata (Willd.) Ohwi], St. John's wort (Hypericum perforatum L.), danshen (Salvia miltiorrhiza Bge.), ginseng (Panax ginseng C.A. Mey.), Japanese raisin tree (Hovenia dulcis Thunb.), ibogaine (Tabernanthe iboga H. Bn.), evening primrose (Oenothera biennis L.), prickly pear fruit (Opuntia ficus indica (L.) Mill.), purple passionflower (Passiflora incarnata L.), thyme (Thymus vulgaris L.), fenugreek seed (Trigonella foenum-graecum L.), ginger (Zingiber officinale Roscoe) and many others drew the attention of researchers. Can, therefore, drugs of natural origin be helpful in the treatment of alcoholism or in decreasing alcohol consumption?(71)
A.1.3. In TCM medicine perspective
Alcohol has long been used as a daily beverage in China and around the world. It is a medicinal substance with various biological activities. According to study by Peking University, in the summarized clinical and primary studies concerning various remedies of TCM for alcohol abuse, including herbal components (such as Kudzu/Pueraria Lobata, Pediculus melo, Hypericumpperforatum L.), decoctions and acupuncture(72).
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to General health http://kylejnorton.blogspot.ca/p/general-health.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
Sources
(a) http://www.cdc.gov/nchs/fastats/liverdis.htm
(67) http://www.ncbi.nlm.nih.gov/pubmed/23101981
(68) http://www.ncbi.nlm.nih.gov/pubmed/18068515
(69) http://www.ncbi.nlm.nih.gov/pubmed/12605067
(70) http://www.ncbi.nlm.nih.gov/pubmed/10930711
(71) http://www.ncbi.nlm.nih.gov/pubmed/22474979
(72) http://www.ncbi.nlm.nih.gov/pubmed/21213394
Treatments
A. Treatments of cirrhosis depend not on the underline causes and stage of the diseases
A.1. Alcohol causes of cirrhosis
A.1.2. In conventional medicine perspective
If the the disease is caused by excessive alcohol drinking, patients will be asked to stop drinking. with help from the professional teams and certain medication. The long-term management of alcoholic liver disease stresses the following(67).
(1) Abstinence of alcohol (Grade 1A), with referral to an alcoholic rehabilitation program;
(2) Adequate nutritional support (Grade 1B), emphasizing multiple feedings and a referral to a nutritionist; (3) Routine screening in alcoholic cirrhosis to prevent complications;
(4) Timely referral to a liver transplant program for those with decompensated cirrhosis;
(5) Avoid pharmacologic therapies, as these medications have shown no benefit.
But according to the study by the Catholic University of Rome, in the intervention to achieve alcohol abstinence represents the most effective treatment for alcohol-dependent patients with liver cirrhosis by investigating the effectiveness and safety of Baclofen, is a GABA(B) receptor agonist in achieving and maintaining alcohol abstinence in patients with liver cirrhosis, showed that baclofen is effective at promoting alcohol abstinence in alcohol-dependent patients with liver cirrhosis. The drug is well tolerated and could have an important role in treatment of these individuals(68).
A.1.2. In herbal medicine perspective
1. Kudzu (Pueraria lobata) and St. John's Wort
In the study to summarizes the findings of the effects on alcohol intake in alcohol-preferring rats of extracts or purified compounds from two of the most promising herbs: kudzu (Pueraria lobata) and St. John's Wort (Hypericum perforatum), a symposium presented at the 2002 RSA meeting in San Francisco. found that
(1) Introduction to the symposium, by David Y. W. Lee and David H. Overstreet; (2) Effects of daidzin on alcohol intake-search for mechanisms of action, by Wing-Ming Keung; (3) Long-term suppressive effects of puerarin on alcohol drinking in rats, by David Overstreet and David Y. W. Lee; (4) St. John's Wort extract reduces alcohol intake in FH and P rats, by Amir Rezvani and David Overstreet; and (5) extracts reduce alcohol intake in Marchigian Sardinian alcohol-preferring rats, by Maurizio Massi(69).
2. Pueraria lobata, Tabernanthe iboga, Panax ginseng, Salvia miltiorrhiza and Hypericum perforatum
In the study to review the most relevant experimental data on the reducing effect of some medicinal herbs on voluntary alcohol intake in animal models of alcoholism, showed that Pueraria lobata, Tabernanthe iboga, Panax ginseng, Salvia miltiorrhiza and Hypericum perforatum proved to be effective in decreasing alcohol consumption. Reduction of alcohol absorption from the gastrointestinal system appears to be a common feature among most of the above plants(70).
3. Other herbs
According to the study by, A number of medicinal plants and pure natural compounds are reported to have preventive and therapeutic effects on alcoholism and alcohol dependency, but their constituents, efficacy and mechanism of action are mostly unknown so far. Recently, kudzu [Pueraria lobata (Willd.) Ohwi], St. John's wort (Hypericum perforatum L.), danshen (Salvia miltiorrhiza Bge.), ginseng (Panax ginseng C.A. Mey.), Japanese raisin tree (Hovenia dulcis Thunb.), ibogaine (Tabernanthe iboga H. Bn.), evening primrose (Oenothera biennis L.), prickly pear fruit (Opuntia ficus indica (L.) Mill.), purple passionflower (Passiflora incarnata L.), thyme (Thymus vulgaris L.), fenugreek seed (Trigonella foenum-graecum L.), ginger (Zingiber officinale Roscoe) and many others drew the attention of researchers. Can, therefore, drugs of natural origin be helpful in the treatment of alcoholism or in decreasing alcohol consumption?(71)
A.1.3. In TCM medicine perspective
Alcohol has long been used as a daily beverage in China and around the world. It is a medicinal substance with various biological activities. According to study by Peking University, in the summarized clinical and primary studies concerning various remedies of TCM for alcohol abuse, including herbal components (such as Kudzu/Pueraria Lobata, Pediculus melo, Hypericumpperforatum L.), decoctions and acupuncture(72).
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to General health http://kylejnorton.blogspot.ca/p/general-health.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
Sources
(a) http://www.cdc.gov/nchs/fastats/liverdis.htm
(67) http://www.ncbi.nlm.nih.gov/pubmed/23101981
(68) http://www.ncbi.nlm.nih.gov/pubmed/18068515
(69) http://www.ncbi.nlm.nih.gov/pubmed/12605067
(70) http://www.ncbi.nlm.nih.gov/pubmed/10930711
(71) http://www.ncbi.nlm.nih.gov/pubmed/22474979
(72) http://www.ncbi.nlm.nih.gov/pubmed/21213394
Cirrhosis Preventions - The Antioxidants
Cirrhosis is defined as a condition of irreversible scarring liver as a
result of liver tissue by fibrosis due to final phase of chronic liver diseases
of that can lead to poor function of the liver and liver failure. According to
the statistics, Number of discharges with chronic liver disease or cirrhosis as
the first-listed diagnosis: 101,000 in 2009 and Deaths per 100,000 population:
10.3 in 2010(a). Hepatitis B infection cause of the disease is very prevalent in
South-East Asia.
Antioxidants to prevent Cirrhosis
1. Probiotics and antioxidants
In the study to to determine the effect of Lactobacillus johnsonii La1 and antioxidants on intestinal flora, endotoxemia, and bacterial translocation in cirrhotic rats, found that rats treated with antioxidants and Lactobacillus johnsonii La1 showed a decrease in endotoxemia with respect to cirrhotic rats receiving water (P<0.05). Antioxidants alone or in combination with Lactobacillus johnsonii La1 can be useful in preventing bacterial translocation in cirrhosis(63).
2. Caryophyllene (CAR)
Caryophyllene (CAR) is a common constituent of the essential oil of numerous plants, vegetables, fruits and medicinal herbs, and has been used as a flavouring agent since the 1930 s. According to the study by Hospital Universitario Virgen de las Nieves, indicated that CAR significantly improved liver structure, and reduced fibrosis and the expression of Col1a1, Tgfb1 and Timp1 genes. Oxidative stress was used to establish a model of HSC activation with overproduction of extracellular matrix proteins. CAR (1 and 10 μm) increased cell viability and significantly reduced the expression of fibrotic marker genes. CAR, a sesquiterpene present in numerous plants and foods, is as a natural antioxidant that reduces carbon tetrachloride-mediated liver fibrosis and inhibits hepatic cell activation(64).
3. Vitamins C and E
Antioxidants vitamins C and E are free radical scavengers. In the study of undertaken to find the therapeutic efficacy of naringenin (NGN) plus vitamins C and E on Cd-induced oxidative hepatotoxicity in Wistar rats, by Annamalai University, showed that treatment with NGN and vitamins C and E in combination more significantly improved the altered biochemical and histopathological changes in the liver of Cd-intoxicated rats than the NGN or vitamins C and E treatment alone(65).
4. Selenium
In the study to investigte the effect of selenium deficiency Effects, induced by thioacetamide, showed that thioacetamide (0.3 g/L) given in drinking water, as expected, caused a significant loss of selenium from the liver. It was accompanied by liver cirrhosis and a significant increase in the liver weight as well as liver to body weight ratio. A significant loss of selenium from spleen was also accompanied by an increase in its weight. Weights of lungs, testis and kidney, however, were not affected by thioacetamide and there was no change in their selenium content. Plasma levels of selenium were significantly reduced in the thioacetamide treated group. All these changes were confirmed to be due to selenium deficiency caused by thioacetamide, as supplementation with selenium reversed these changes. The mode of action of selenium is unknown but may involve anti-oxidant defense mechanisms(66).
5. Etc.
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to General health http://kylejnorton.blogspot.ca/p/general-health.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(a) http://www.cdc.gov/nchs/fastats/liverdis.htm
(63) http://www.ncbi.nlm.nih.gov/pubmed/12217598
(64) http://www.ncbi.nlm.nih.gov/pubmed/22717234
(65) http://www.ncbi.nlm.nih.gov/pubmed/21697638
(66) http://www.ncbi.nlm.nih.gov/pubmed/9746205
Antioxidants to prevent Cirrhosis
1. Probiotics and antioxidants
In the study to to determine the effect of Lactobacillus johnsonii La1 and antioxidants on intestinal flora, endotoxemia, and bacterial translocation in cirrhotic rats, found that rats treated with antioxidants and Lactobacillus johnsonii La1 showed a decrease in endotoxemia with respect to cirrhotic rats receiving water (P<0.05). Antioxidants alone or in combination with Lactobacillus johnsonii La1 can be useful in preventing bacterial translocation in cirrhosis(63).
2. Caryophyllene (CAR)
Caryophyllene (CAR) is a common constituent of the essential oil of numerous plants, vegetables, fruits and medicinal herbs, and has been used as a flavouring agent since the 1930 s. According to the study by Hospital Universitario Virgen de las Nieves, indicated that CAR significantly improved liver structure, and reduced fibrosis and the expression of Col1a1, Tgfb1 and Timp1 genes. Oxidative stress was used to establish a model of HSC activation with overproduction of extracellular matrix proteins. CAR (1 and 10 μm) increased cell viability and significantly reduced the expression of fibrotic marker genes. CAR, a sesquiterpene present in numerous plants and foods, is as a natural antioxidant that reduces carbon tetrachloride-mediated liver fibrosis and inhibits hepatic cell activation(64).
3. Vitamins C and E
Antioxidants vitamins C and E are free radical scavengers. In the study of undertaken to find the therapeutic efficacy of naringenin (NGN) plus vitamins C and E on Cd-induced oxidative hepatotoxicity in Wistar rats, by Annamalai University, showed that treatment with NGN and vitamins C and E in combination more significantly improved the altered biochemical and histopathological changes in the liver of Cd-intoxicated rats than the NGN or vitamins C and E treatment alone(65).
4. Selenium
In the study to investigte the effect of selenium deficiency Effects, induced by thioacetamide, showed that thioacetamide (0.3 g/L) given in drinking water, as expected, caused a significant loss of selenium from the liver. It was accompanied by liver cirrhosis and a significant increase in the liver weight as well as liver to body weight ratio. A significant loss of selenium from spleen was also accompanied by an increase in its weight. Weights of lungs, testis and kidney, however, were not affected by thioacetamide and there was no change in their selenium content. Plasma levels of selenium were significantly reduced in the thioacetamide treated group. All these changes were confirmed to be due to selenium deficiency caused by thioacetamide, as supplementation with selenium reversed these changes. The mode of action of selenium is unknown but may involve anti-oxidant defense mechanisms(66).
5. Etc.
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to General health http://kylejnorton.blogspot.ca/p/general-health.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(a) http://www.cdc.gov/nchs/fastats/liverdis.htm
(63) http://www.ncbi.nlm.nih.gov/pubmed/12217598
(64) http://www.ncbi.nlm.nih.gov/pubmed/22717234
(65) http://www.ncbi.nlm.nih.gov/pubmed/21697638
(66) http://www.ncbi.nlm.nih.gov/pubmed/9746205
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