Tuesday, 5 November 2013

Chinese Herbs – Lu Tou (Semen Phaseoli radiati)

Lu Tou is also known as Mung bean or Rice bean. The sweet, cold and non toxic herb has been used in TCM as antipyretic, diuretic and antidote for toxicity of arsenic, and poisons from plants or minerals agent and to treat edema, headache, etc., as it clears Heat, expels toxins, disperses Summer-Heat, etc., by enhancing the functions of heart and spleen channels

Ingredients
1. Protein
2. Fat
3. Carbohydrate
4. Fiber
5. Calcium
6. Iron
7. Magnesium
8. Phosphorus
9. Potassium
10. Selenium
11. Vitamin C
12. Phytosterols
13. Amino acids
14. Tryptophan
15. Threonine
16. Isoleucine
17. Leucine
18. Lysine
19. Methionine
20. Cystine
21. Phenylalanine
22. Tyrosine
23.  Valine
24. Arginine
25. Histidine
26. Alanine
27. Aspartic acid
28.  Glutamic acid
29. Glycine
30. Proline
31. Serine
32. Etc.

Health Benefits
1. Antioxidants
In the study to evaluate the AOA of cereals, millets, pulses and legumes, commonly consumed in India and assessed the relationship with their total phenolic content (TPC). AOA was assessed by DPPH (2,2-Diphenyl-1-picryl hydrazyl) radical scavenging assay, ferric reducing antioxidant power (FRAP) assay and reducing power. Among cereals and legumes, Finger millet (Ragi) and black gram dhal (Phaseolus mungo Roxb) had the highest TPC, the values being 373 and 418 mg/100 g respectively, while rice (Oryza sativa) and green gram dhal (Phaseolus aureus Roxb) showed the least (47.6 and 62.4 mg/100 g). In the present study, FRAP (r = 0.91) and reducing power (r = 0.90) showed significant correlation with TPC in cereals and millets, but not in pulses and legumes(1)
2. Oxidative properties 
In the investiagtion of the effects of kaempferol on the oxidative and phosphorylative properties of plant mitochondria from potato tubers and etiolated mung bean (Phaseolus aureus Roxb.) hypocotyls, showed that Kaempferol inhibited the state 3 oxidation rate of malate, NADH, and succinate, but was without effect on the ascorbate-tetramethyl p-phenylenediamine oxidation rate. The inhibition was almost the same whether the mitochondria were in state 3 or in an uncoupled state 3. When 180 micromolar kaempferol was added during state 4, the tight coupling of succinate or NADH oxidation was not released(2)
3. Etc.

Side Effects
1. Do not use the herb in Patient with weak digestion, chronic pain in the lower back with kidney deficiency
2. Do not use the herb in case of spleen deficiency
3. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/19374263
(2) http://www.ncbi.nlm.nih.gov/pubmed/16662212

Chinese Herbs– Lu Hui (Herba Aloes)

Lu Hui is also known as Aloe vera. The bitter and cold herb has been used in TCM as anti certain tumors, antihepatic carcinoma, anti-diabetic, antifungal agent and to strengthen immune system. promote healing wounds and burns, etc., as it clears the Liver, eliminates parasites, etc., by enhancing the functions of large intestine, liver and stomach channels.


Ingredients
1. Barbaloin
2.Isobarbaloin
3. Homonataloin
4. Chrysophanol
5. Chrysophanol glucoside
6. Anthranol
7. Isoelutherol glucoside
8. Aloesaponarin
9. Helminthosporin
10 Aloesin
11. Aloenin
12. Tetrahydroanthracene glucoside
13. Etc.

Health Benefits

1. Cancer
Eventhough Aloe Vera is not one of the herb used in herbal medicine in treating cancer, but according to some studies, Aloe Vera has a property of inhibiting the growth of cancer and apoptosis, according to the study of “Medicinal plants used as antitumor agents in Brazil: an ethnobotanical approach” by de Melo JG, Santos AG, de Amorim EL, do Nascimento SC, de Albuquerque UP., posted in PubMed (1), researchers found that our analysis included papers published between 1980 and 2008. A total of 84 medicinal plant species were reported to be used for cancer and tumor prevention or treatment; 69.05% of these were cited as being used for the treatment of tumors and cancer in general and 30.95% for specific tumors or cancers. The plants that were cited at a higher frequency were Aloe vera, Euphorbia tirucalli, and Tabebuia impetiginosa.
2. Antiaging (Prevent wrinkle)
There are many products of Aloe Vera sold commercially as an natural anti wrinkle magic in health perspective, is Aloe Vera really has that property? according to the study of “Dietary Aloe Vera Supplementation Improves Facial Wrinkles and Elasticity and It Increases the Type I Procollagen Gene Expression in Human Skin in vivo” by Cho S, Lee S, Lee MJ, Lee DH, Won CH, Kim SM, Chung JH., posted in PubMed(2), researchers filed the conclusion that Aloe gel significantly improves wrinkles and elasticity in photoaged human skin, with an increase in collagen production in the photoprotected skin and a decrease in the collagen-degrading MMP-1 gene expression. However, no dose-response relationship was found between the low-dose and high-dose groups.
3. Laxation
Aloe Vera beside enhances motility of the intestines, but also increases fecal volume and normalizes body weight, that can reduce the risk of constipation, according to the study of “The effect of Aloe ferox Mill. in the treatment of loperamide-induced constipation in Wistar rats” by Wintola OA, Sunmonu TO, Afolayan AJ., posted in PubMed(3)
4. Skin
Aloe Vesa has been used as skin care as a cosmetic and pharmaceutical ingredients, according to the study of ” Innovations in natural ingredients and their use in skin care’ by Fowler JF Jr, Woolery-Lloyd H, Waldorf H, Saini R., posted in PubMed(4), researchers wrote that Certain ingredients, such as colloidal oatmeal and aloe vera, have been identified as beneficial in the treatment of psoriasis and atopic dermatitis, respectively, due to their anti-inflammatory properties.
5. Wound
Aloe Vera has been used in herbal medicine beside improves wound healing as a result of the presence of mannose-6-phosphate, according to the study of “Anti-inflammatory and wound healing activity of a growth substance in Aloe vera” by Davis RH, Donato JJ, Hartman GM, Haas RC., posted in PubMed(5), but also enhances burn healing, according to the study of “Effect of aloe cream versus silver sulfadiazine for healing burn wounds in rats” by Hosseinimehr SJ, Khorasani G, Azadbakht M, Zamani P, Ghasemi M, Ahmadi A., posted in PubMed(6), researchers concluded that this study showed aloe cream to significantly increase reepithelialization in burn wounds as compared with silver sulfadiazine.
6. Diabetes
Aloe Vesa helps to treat diabetes by controlling the blood glucose, reducing hepatic transaminases plasma and tissue (liver and kidney) cholesterol, triglycerides, free fatty acids and phospholipids and improvement in plasma insulin levels, according to the study of “Beneficial effects of aloe vera leaf gel extract on lipid profile status in rats with streptozotocin diabetes” by Rajasekaran S, Ravi K, Sivagnanam K, Subramanian S., posted in PubMed(7)
7. Immune system
Aloe Vera enhances the immune system by enhancing the immunological parameters in cellular immune response and phagocytosis, according to the study of “Modulation of Immune Response of BALB/Mice Bearing Lymphoma L5178Y Treated with Bitter Yellow Juice of Aloe vera (L) in vivo” by Oronzo-Barocio A, Zaitseva G, Chavez-Anaya A, Arceta-Gonzalez VI, Puebla-Perez AM, Alfaro-Bustamante F, Zimina IV, Arion VY., posted in PubMed(8)
8. Human papillomavirus (HPV)
The herb beside contains a antibactera and fungal properties, it also enhance the immune system infifgting against Human papillomavirus, according tothe study of “A novel polyherbal microbicide with inhibitory effect on bacterial, fungal and viral genital pathogens” Talwar GP, Dar SA, Rai MK, Reddy KV, Mitra D, Kulkarni SV, Doncel GF, Buck CB, Schiller JT, Muralidhar S, Bala M, Agrawal SS, Bansal K, Verma JK., posted in PubMed(9)
9. Antioxidants
Aloe Vera also is popular used in treating infection and inflamation as a result of its antioxidant property. according to the study of ” In Vitro Antimicrobial and Antioxidant Activities of Anthrone and Chromone from the Latex of Aloe harlana Reynolds” by Asamenew G, Bisrat D, Mazumder A, Asres K., posted in PuibMed(10)
10. Weight loss
Since aloe Vera contains high amounts of collagen fiber, it can use as a weight loss program as more energy are needed for the digestive process, according to the article of “Collegen” posted in Wikipedia in the “use” section(11)
11. Low levels of cholesterol
Aloe Vera can help to reduce the levels of total cholesterol, LDL-cholesterol, VLDL-cholesterol and triglycerides in blood serum, thus reducing the risk of cardivascular disease, according to the study of “Lipid lowering activity of hydrosoluble chitosan and association with Aloe vera L. and Brassica olearaceae” L’ by Geremias R, Pedrosa RC, Locatelli C, de Fávere VT, Coury-Pedrosa R, Laranjeira MC., posted in PubMed(12)
12. Etc.

Side Effects

1. Do not use the herb in case of spleen deficiency
2. Overdose or prolonged period of use can cause kidney damage
3. Do not use the herb in newborn, children or if you are pregnant or breast feeding with out approval first with the related field specialist
4. Etc.
 
 Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/21528006
(2) http://www.ncbi.nlm.nih.gov/pubmed/20548848
(3) http://www.ncbi.nlm.nih.gov/pubmed/20723249
(4) http://www.ncbi.nlm.nih.gov/pubmed/20626172
(5) http://www.ncbi.nlm.nih.gov/pubmed/8169808
(6) http://www.ncbi.nlm.nih.gov/pubmed/20361881
(7) http://www.ncbi.nlm.nih.gov/pubmed/16487267
(8) http://www.ncbi.nlm.nih.gov/pubmed/12687115
(9) http://www.ncbi.nlm.nih.gov/pubmed/18571386
(10) http://www.ncbi.nlm.nih.gov/pubmed/21452374
(11) http://en.wikipedia.org/wiki/Collagen
(12) http://www.ncbi.nlm.nih.gov/pubmed/16557611
(13) http://www.ncbi.nlm.nih.gov/pubmed/17726067

Chinese Herbs – Lu Lu Tong(Fructus Liquidambaris)

Lu Lu Tong or Feng Xiang is also known as Sweetgum Fruit. The bitter and neutral herb has been used in TCM to treat stiffness and tightness of arms and legs, irregular menses, hypomenorrhea, lactation obstruction promote urination, get rid of edema, piles, parasites, etc. as it clears Heat, expels Wind; eliminates Water, calms pain,etc., by enhancing the functions of liver and stomach channels.

Ingredients
1. Cinnamic acid
2. L-borneol
3. Resin
4. Benzine
5. Etc.
Health Benefits
1. Chemical composition
In the study to investigate the chemical composition in the fruits of Liquidambar formana Hance, Eleven compounds were isolated and identified as beta-sitosterol (1), 3-oxo-11 alpha, 12 alpha-epoxyleanan-28, 13 beta-olide (2), 3-oxo-12 alpha-hydroxy-oleanan-28, 13 beta-olide (3), 3 alpha-acetyloxy-25-hydroxyolean-12-en-28-oic acid (4), oleanolic acid (5), ursolic acid (6), daucosterol (7), betulonic acid (8), gallic acid (9), nonacosane (10) and n-triacontanoic acid (11).(1)
2. Mammary gland growth and function
In the study to examine the fruits of Lulutong and the seeds of Wangbuliouxing, which are the natural products used widely as the components of herbal medicine in China for the improvement of lactation and the therapy of breast disorders, found that The chronic administration of each agent in drinking water improved several parameters; however, the mode of action differed markedly among agents.(2)
3. Etc.

Side Effects
1. Do not use the herb in Newborn, children, or if you are pregnant or breast feeding without consulting firast with the related field specialist.
2. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed?term=Fructus%20Liquidambaris
(2) http://www.ncbi.nlm.nih.gov/pubmed/1381968

#Healthy Foods - Honey


Honey
The rich golden liquid is the miraculous product made by bees using nectar from flowers. It is considered as one of healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.

Nutritional Supplements
1. Carbohydrates
2. Sugars
3. Protein
4. Water
5. Riboflavin (Vitamin B2)
6. Niacin (Vitamin B3)
7. Pantothenic acid (Vitamin B5)
8. Vitamin B6
9. Folate (Vitamin B9)
10. Vitamin C
11. Calcium
12. Iron
13. Magnesium
14. Phosphorus
15. Potassium
16. Sodium
17. Zinc
18. Etc.

Health benefits
A. health benefits according to studies
1. Acute cough in children
In the investigation of the effectiveness of honey for acute cough in children in ambulatory settings found that Dextromethorphan and honey did not differ significantly on cough frequency (MD -0.49; 95% CI -1.15 to 0.17); cough severity (MD -0.50; 95% CI -1.28 to 0.29), bothersome cough (MD -0.29; 95% CI -1.14 to 0.56) and sleep quality of the children (MD -0.70; 95% CI -1.57 to 0.17) or their parents (MD -0.34; 95% CI -1.24 to 0.55) and concluded that we found insufficient evidence to advise for or against the use of honey for acute cough in children, according to "Honey for acute cough in children" by Oduwole O, Meremikwu MM, Oyo-Ita A, Udoh EE.(a)

2. Wound healing
In the assessment of Potential role of honeyon wound healing found that honey may improve healing times in mild to moderate superficial and partial thickness burns compared with some conventional dressings. Honey dressings as an adjuvant to compression do not significantly increase leg ulcer healing at 12 weeks. There is insufficient evidence to guide clinical practice in other areas. according to "Honey as a topical treatment for wounds" by Jull AB, Rodgers A, Walker N.(b)

3. Antiproliferative effect
In the identification of honey and its effect on keloid fibroblasts found that the methanolic honey extraction has an antiproliferative effect on keloid fibroblasts and a range of volatile compounds has been identified from Tualang honey. The antiproliferative effect of keloid fibroblasts towards Tualang honey may involve cell signaling pathway. Identifying other volatile compounds from different organic solvents should be carried out in future, according to "Antiproliferative effect of methanolic extraction of tualang honey on human keloid fibroblasts" by Nurul Syazana MS, Halim AS, Gan SH, Shamsuddin S.(c)

4. Antibacterial properties
In the classification of Honey possesses therapeutic potential on antibiotic resistance of bacteria
found that Tualang honey exhibited variable activities against different microorganisms, but they were within the same range as those for manuka honey. This result suggests that tualang honey could potentially be used as an alternative therapeutic agent against certain microorganisms, particularly A. baumannii and S. maltophilia, according to "The antibacterial properties of Malaysian tualang honey against wound and enteric microorganisms in comparison to manuka honey" by Tan HT, Rahman RA, Gan SH, Halim AS, Hassan SA, Sulaiman SA, Kirnpal-Kaur B.(d)

5. Anti-inflammatory and antioxidant effects
In assessment of Tualang honey and its anti-inflammatory and antioxidant effects found that Tualang honey has almost the equal effects when compared with the conventional treatment in treating alkali injury on rabbit's eye. Future research with more number of rabbits and control group is warranted to explore the anti-inflammatory and antioxidant effects of Tualang honey, according to "Anti-inflammatory and antioxidant effects of Tualang honey in alkali injury on the eyes of rabbits: experimental animal study" by Bashkaran K, Zunaina E, Bakiah S, Sulaiman SA, Sirajudeen K, Naik V.(e)

6. Etc.

B. Health benefits according to concentration
Energy
Honey contains high amount of glucose and fructose that are simple sugar (monosaccharide) played an important role to enhance energy production in carbohydrate metabolism, as they
are absorbed by the body quickly through insulin and potassium.

C. Other health benefits
1. Antiseptic and antibacterial properties
Recently research study that honey have the antiseptic and antibacterial properties as it increases the immune system in fighting the forming of free radicals causes of inflammation and infection causes of infection due to enzyme glucose oxidase, according to the study of `Antibacterial properties of tualang honey and its effect in burn wound management: a comparative study`by Nasir NA, Halim AS, Singh KK, Dorai AA, Haneef MN., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/20576085), researchers found that Tualang honey has a bactericidal as well as bacteriostatic effect. It is useful as a dressing, as it is easier to apply and is less sticky compared to Manuka honey. However, for Gram positive bacteria, tualang honey is not as effective as usual care products such as silver-based dressing or medical grade honey dressing.

2. Diabetes chronic wound
External used is proven to be effective for treating diabetes chronic wound that antibiotic can not be used, according to the study of `Safety and efficacy of a new honey ointment on diabetic foot ulcers: a prospective pilot study`by Abdelatif M, Yakoot M, Etmaan M., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/18376651, researchers indicated that Ninety-six per cent of the patients in groups 1 and 2 responded well, with a complete cure, defined as'complete closure of the ulcer without signs of underlying bone infection' by the end of week 9 and for the duration of the six-month follow-up period. All of the ulcers in group 1 healed, as did 92% of those in group 2. All patients in group 3 healed following surgical excision, debridement of necrotic tissue and conservative treatment with PEDYPHAR ointment.

3. Phosphorus
Beside providing strength to bones and teeth by working together with calcium according to the study of `[The effect of one year therapy with recombinant human growth hormone (rhGH) on growth velocity, calcium-phosphorus metabolism, bone mineral density and changes in body composition in children with growth hormone deficiency (GHD)].[Article in Polish]`by Zak T, Basiak A, Zubkiewicz-Kucharska A, Noczyńska A., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/20529605), it also works with riboflavin and niacin to improve the digestive system in absorbing vital nutrients.

4. Iron and iron deficiency anemia
Iron is essential for the production of red blood cells and carrying life-giving oxygen to human cells. Deficiency of iron causes anemia, anemia of chronic disease, cough, anemia in pregnancy, etc., leading to reducing blood flow to the reproductive organ according to the study of `The effects of iron deficiency on estradiol-induced suppression of erythropoietin induction in rats: implications of pregnancy-related anemia` by Horiguchi H, Oguma E, Kayama F., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/15784734)

5. Etc

Side effects
1. Because of the presence of botulinum endospores, children under one year of age should not be given honey
2. Honey may be poison if produced from the flowers of oleanders, rhododendrons, mountain laurels, sheep laurel, and azaleas etc.
3. It may contain traces of heavy metals, pesticides, etc.


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Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/20091616
(b) http://www.ncbi.nlm.nih.gov/pubmed/22050652
(c) http://www.ncbi.nlm.nih.gov/pubmed/21943200
(d) http://www.ncbi.nlm.nih.gov/pubmed/19754926
(e) http://www.ncbi.nlm.nih.gov/pubmed/21982267

#Healthy Foods - Blackstrap molasses



Blackstrap molasses
Molasses is the juice is boiled to concentration which promotes the crystallization of the sugar, made by extracting from the canes, usually by crushing or mashing, after the sugar cane plant is harvested and stripped of its leaves. The concentration of this first boiling and of the sugar crystals is first molasses, which has the highest sugar content.
Blackstrap molasses is the third boiling of the sugar syrup with of sucrose from the original juice has been crystallized and removed.


Nutritional Supplements
1. Glucose
2. Fructose
3. Biotin
4. Calcium
5. Potassium
6. Chloride
7. Manganese
8. Selenium
9. Copper
10. Iron
11. Magnesium
12. Potassium
13. Etc.

Health benefits
A. Health benefits according to studies
1. Antioxidant
In the investigation of raw cane sugar, plant saps/syrups (eg, maple syrup, agave nectar), molasses, honey, and fruit sugars (eg, date sugar) and the total antioxidant content of natural sweeteners found that ark and blackstrap molasses had the highest FRAP (4.6 to 4.9 mmol/100 g), while maple syrup, brown sugar, and honey showed intermediate antioxidant capacity (0.2 to 0.7 mmol FRAP/100 g). Based on an average intake of 130 g/day refined sugars and the antioxidant activity measured in typical diets, substituting alternative sweeteners could increase antioxidant intake an average of 2.6 mmol/day, similar to the amount found in a serving of berries or nuts, according to "Total antioxidant content of alternatives to refined sugar" by Phillips KM, Carlsen MH, Blomhoff R.(a)

2. Vibrio furnissii M1
In the observation of "Production of alternatives to fuel oil from organic waste by the alkane-producing bacterium, found that Crude blackstrap molasses were also converted into alkanes with a conversion ratio of 20% (half of that in an authentic sucrose medium) of the total carbon consumption, according to "Production of alternatives to fuel oil from organic waste by the alkane-producing bacterium, Vibrio furnissii M1" by Park MO, Heguri K, Hirata K, Miyamoto K.(b)

3. Microbial production
In the observation of microbial production of fermentation of blackstrap molasses
found that A two-stage fermentation process was developed for the conversion of sugar or molasses of various types to propionic acid and vitamin B12. By fermentation of blackstrap molasses (from sugar beet and sugar cane) in the first fermentation stage 17.7 g propionic acid l-1 with a yield of 0.5 g propionic acid g-1 carbohydrate was produced with a dilution rate of 0.25 h-1. In the second stage 49 mg vitamin B12 1-1 was produced at a dilution rate of 0.03 h-1.(c)

4. Etc.

B. Health benefits according to concentration
1. Manganese
Beside it is important in forming connective tissues and building of essential enzymes for building healthy bones, manganese also helps in regulating the normal function of of thyroid growth hormone, according to the study of "The effect of manganese supply on thyroid hormone metabolism in the offspring of manganese-depleted dams" by Eder K, Kralik A, Kirchgessner M., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/8971361) and blood sugar level, according to the study of "Manganese corroles prevent intracellular nitration and subsequent death of insulin-producing cells" by Okun Z, Kupershmidt L, Amit T, Mandel S, Bar-Am O, Youdim MB, Gross Z., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/19715343)

2. Copper and Iron
Copper plays a role in a wide range of physiological processes, such as iron utilization of enhancing the hemoglobin. and reduction of malabsorption syndrome. according to the study of "Beneficial effect of goat milk on nutritive utilization of iron and copper in malabsorption syndrome" by Barrionuevo M, Alferez MJ, Lopez AI, Sanz SM, Campos MS., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/11949871). Iron is an integral component of hemoglobin in transporting oxygen from the lungs to all body cells, thus increasing the energy use for daily activities.

3. Calcium
In the investigation of micronutrients, calcium (Ca) and inorganic (i) phosphate (P) ,the two main constituents of hydroxyapatite and theirs effect on bone health found that they are endowed with a transport system that accumulates Pi inside the matrix vesicles, followed by the influx of Ca ions. This process leads to the formation of hydroxyapatite crystal and its subsequent association with the organic matrix collagen fibrils. In addition to this structural role, both Ca and Pi positively influence the activity of bone-forming and bone-resorbing cells. Pi plays a role in the maturation of osteocytes, the most abundant cells in bone. Osteocytes are implicated in bone mineralization and systemic Pi homeostasis, according to "Calcium and phosphate: a duet of ions playing for bone health" by Bonjour JP.(1)

4. Potassium
Potassium beside is important in maintaining the regular contraction and relaxation of the muscle, that helps to reducing the risk of hypokalemia, it also helps the lymphatic system in regulating the levels of fluid in the body, thus lessening the risk of lymphedema, swelling caused by the accumulation of lymph fluid. In a study of "Narrative review: evolving concepts in potassium homeostasis and hypokalemia" by Greenlee M, Wingo CS, McDonough AA, Youn JH, Kone BC., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/19414841), researchers found that recent experimental insights into the participation of feedback and feedforward control mechanisms in potassium homeostasis. New data make clear that feedforward homeostatic responses activate when decreased potassium intake is sensed, even when plasma potassium concentration is still within the normal range and before frank hypokalemia ensues, in addition to the classic feedback activation of renal potassium conservation when plasma potassium concentration decreases.

5. Etc.

C. Other health benefits
1. Bone density
Since blackstrap molassaes contains high amount of calcium, it helps to build stronger, denser bones early in life and keeps bones strong and healthy later in life, thus reducing the risk of osteoporosis. Vitamin D is necessary for the absorption of calcium, according to the article of "Calcium supplements in people with osteoporosi" by John G F Cleland, Klaus Witte, Sue Steel, posted in BMJ (http://www.bmj.com/content/341/bmj.c3856.full), researchers wrote that Calcium supplements, given alone, improve bone mineral density,but they are ineffective in reducing the risk of fractures and might even increase risk.

3. Glucose and Fructose
Glucose and Fructose are simple sugar (monosaccharide) played an important role to enhance energy production in carbohydrate metabolism for brain cells need, through a chain chemical action of insulin produced by pancreas and potassium.

4. Magnesium
Beside helping to maintain the healthy bone through the proper ratio with calcium, according to the study of "Magnesium deficiency and osteoporosis: animal and human observations" by Rude RK, Gruber HE., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/15607643) magnesium also plays an essential role in relieving acute asthma by promoting the relaxation of bronchial muscles and normalizing breathing, according to the study of "Inhaled magnesium sulfate in the treatment of acute asthma" by Blitz M, Blitz S, Beasely R, Diner BM, Hughes R, Knopp JA, Rowe BH., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/16235345) researchers found that Nebulised inhaled magnesium sulfate in addition to beta2-agonist in the treatment of an acute asthma exacerbation, appears to have benefits with respect to improved pulmonary function in patients with severe asthma and there is a trend towards benefit in hospital admission. Heterogeneity between trials included in this review precludes a more definitive conclusion.

5. Etc

Side effects
Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/19103324
(b) http://www.ncbi.nlm.nih.gov/pubmed/15659187
(c) http://www.ncbi.nlm.nih.gov/pubmed/7765100
(1) http://www.ncbi.nlm.nih.gov/pubmed/22081690

#Healthy Foods - Raspberries




Raspberries are perennial, the edible fruit of a multitude of plant species in the genus Rubus belong to the family Rosaceae, originated from Europe. Because of their commercial values and health benefits, they have been grown for processing of quick frozen (IQF) fruit, purée, juice, or as dried fruit used in a variety of grocery products.

Nutritional Supplements
1. Carbohydrates
2. Glucose
3. Fiber
4. monounsaturated fat
5. polyunsaturated fat
6. Protein
7. Vitamin A and beta-carotene
8. Vitamin B2
9. Vitamin B3
10. Folate
11. Vitamin C
12. Calcium
13. Iron
14. Sodium
15. Magnesium
16. Manganese
17. Copper
18. Potassium
19. Etc.

Health benefits
A. Health benefits according to studies
1.
Human healthIn the investigation of Raspberries and its effect on human health found that the nutritional and phytochemical compositions of red raspberries and their absorption, metabolism, and biological activity are reviewed. Finally, future directions of research are also identified, according to "Raspberries and human health: a review" by Rao AV, Snyder DM.(a)

2. Bioavailability of anthocyanins and ellagitannins

In the assessment of raspberries and its Bioavailability of anthocyanins and ellagitannins effects found that no intact or conjugated forms of ellagitannins were detected in urine from either healthy subjects or ileostomy volunteers. However, in healthy subjects, but not the ileostomists, ellagitannins were catabolized with the appearance of urolithin A-O-glucuronide, two of its isomers, and urolithin B-O-glucuronide in urine collected 7-48 h after raspberry consumption. There was marked variation in the urolithin profile of individual volunteers, indicating differences in the colonic microflora responsible for ellagitannin degradation, according to "Bioavailability of anthocyanins and ellagitannins following consumption of raspberries by healthy humans and subjects with an ileostomy" by
González-Barrio R, Borges G, Mullen W, Crozier A.(b)

3. Anti cancers
In the analyzing black raspberries extract and its effect on inhibition of preclinical models of epithelial cancer cell growth and tumor formation found that black raspberries and their bioactive components represent promising candidates for future phytochemical-based mechanistic pathway-targeted cancer prevention strategies, according to "A black raspberry extract inhibits proliferation and regulates apoptosis in cervical cancer cells' By Zhang Z, Knobloch TJ, Seamon LG, Stoner GD, Cohn DE, Paskett ED, Fowler JM, Weghorst CM.(c)

4. Intestinal tumorigenesis
In the observation of Freeze-dried black raspberries (BRB)and its effect on intestinal carcinogenesis found that BRBs inhibit tumor development in Apc1638+/- mice by suppressing β-catenin signaling and in Muc2-/- mice by reducing chronic inflammation. Intestinal cell proliferation was inhibited by BRBs in both animal models; however, the extent of mucus cell differentiation was not changed in either model. Collectively, our data suggest that BRBs are highly effective in preventing intestinal tumor development in both Apc1638+/- and Muc2-/- mice through targeting multiple signaling pathways, according to "Black raspberries inhibit intestinal tumorigenesis in apc1638+/- and Muc2-/- mouse models of colorectal cancer" by Bi X, Fang W, Wang LS, Stoner GD, Yang W.(d)

5. Neurodegenerative diseases
In the identification of Resveratrol found skin of grapes, raspberries, mulberries, pistachios and peanuts and theirs effect neurodegenerative diseases, found that resveratrol shows effects in in vitro models of epilepsy, Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, and nerve injury. However, evidences in vivo as well as in human beings are still lacking. Thus, further investigations on the pharmacological effects of resveratrol in vivo are necessary before any conclusions on its effects on neurodegenerative diseases can be obtained, according to "Resveratrol: a natural compound with pharmacological potential in neurodegenerative diseases" by Rocha-González HI, Ambriz-Tututi M, Granados-Soto V.(e)

6. Etc.

B. Health benefits according to concentration
1. Vitamin C
In the evaluation of pulmonary dysfunction. and it effects on pulmonary dysfunction found that At present, evidence from randomised-controlled trials is insufficient to recommend a specific role for vitamin C in the treatment of asthma. Further methodologically strong and large-scale randomised controlled trials are needed in order to address the question of the effectiveness of vitamin C in children with asthma but some outcome data showed effectiveness on lung function, symptom scores, IgE levels and inhaled steroid use. One small study showed a significant difference in % drop in FEV1 post-exercise, according to the study of "Vitamin C supplementation for asthma" by Kaur B, Rowe BH, Arnold E.(1)

2. Manganese
Manganese beside is a mineral essential for energy production and metabolism of foods, it also helps to improve immune-system functioning that reduces the risk of inflammation, according to the study of "The effects of 3, 4 or 5 amino salicylic acids on manganese-induced neuronal death: ER stress and mitochondrial complexes" by Yoon H, Lee GH, Kim DS, Kim KW, Kim HR, Chae HJ., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/21477646 researchers indicated that the salicylate analogues and the antioxidants did not mediate ER stress in this model. The salicylate analogues reduced reactive oxygen species (ROS) and reversed the deficient mitochondrial membrane potential that was induced by Mn. Taken together, the 3, 4, 5 ASA worked in a similar way, regulating the Mn-induced mitochondrial dysfunction and protecting cells.

3. Dietary Fibers
Daily intake of right amount of fibers can prvent and treata. Diabetes, as Increased consumption of vegetables, whole grains, and soluble and insoluble fiber is associated with improved glucose metabolism in both diabetic and nondiabetic individuals. Improvements in insulin sensitivity and glucose homeostasis were more evident in participants following a plant-based diet compared with other commonly used diets, according to the study of "Efficacy of high-fiber diets in the management of type 2 diabetes mellitus" by Wolfram T, Ismail-Beigi F.(2)

4. Vitamin K
a. Degenerative diseases of ageing
Long-term vitamin K inadequacy may reduce the function of supporting the carboxylation of at least some of these Gla-protein that can lead the development of degenerative diseases of ageing including osteoporosis and atherosclerosis, according to the study of "Vitamin K, osteoporosis and degenerative diseases of ageing" by Cees Vermeer and Elke Theuwissen(3)

b. Intracranial bleeding
In a study in the 4-year study period, 16/64 (25%) of the infants admitted with intracranial bleeding had late intracranial VKDB, resulting in an overall incidence of 2.1/100,000 live births (95% confidence interval 1.2-3.5) conducted by University Medical Center Utrecht(4) indicated that Intracranial bleeding may be associated with vitamin K deficiency

5. Magnesium
Magnesium not only important for bone health, according to the study of "Magnesium, zinc, copper, manganese, and selenium levels in postmenopausal women with osteoporosis. Can magnesium play a key role in osteoporosis?" by Odabasi E, Turan M, Aydin A, Akay C, Kutlu M(4) but also play and important role in protecting against Alzheimer's disease, according to the study of "Altered ionized magnesium levels in mild-to-moderate Alzheimer's disease" by Barbagallo M, Belvedere M, Di Bella G, Dominguez LJ.(5)

6. Etc.

C. Other health benefits
1. Anthocyanin
Anthocyanin pigments that produces the red color of the fruit, are assembled like all other flavonoids that inhibit the promotion and progression of tumor and cells by accelerating the rate of cell turnover effectively making the cancer cells die faster, according to the study of "Anticancer activities of an anthocyanin-rich extract from black rice against breast cancer cells in vitro and in vivo" by Hui C, Bin Y, Xiaoping Y, Long Y, Chunye C, Mantian M, Wenhua L., posted in PebMed (http://www.ncbi.nlm.nih.gov/pubmed/21058201)
2. Antioxidant
Vitamin C or ascorbic acid is a powerful antioxidant which inhibits the forming of the free radical due to oxidative stress. It also enhances the function of immune system in guarding our body against foreign invasion, thus reducing the risk of inflammatory and infectious diseases, according to the study of "Role of ascorbic acid in scavenging free radicals and lead toxicity from biosystems" by Tariq SA., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/17914166)

3. Ellagic acid
Ellagic acid in raspberries helps to prevent unwanted damage to cell membranes caused by oxidative free radicals by directly inhibiting the DNA binding of certain carcinogens, According to the article of “BIOLOGICAL FUNCTIONALITY OF ELLAGIC ACID: A REVIEW” by D.A. VATTEM and K. SHETTY , Article first published online: 30 JUN 2005, posted in Wiley Online Library, researchers indicated that in abstract, in this article, we have revised the existing models and have proposed a comprehensive model for the antioxidant response-linked mechanism of the action of ellagic acid from fruits at the early stages of host cellular response by the modulation of enzyme response to maintain cellular homeostasis in eukaryotes and by inhibiting the survival in pathogenic prokaryotes.

4. Mucular Degeneration
Muscular degeneration is a medical condition of aging, causing a loss of vision in the center of the visual field. Antioxidant such as vitamins and zinc reduce the risk of the diseases from vision loss due to aging, according to the study of "Age-related macular degeneration" by Coleman HR, Chan CC, Ferris FL 3rd, Chew EY., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/19027484), researchers wrote in abstract that Treatment with antioxidant vitamins and zinc can reduce the risk of developing advanced age-related macular degeneration by about a quarter in those at least at moderate risk.
5. Bone structure
Manganese beside is an essential for proper and normal growth of human bone structure by increasing the mineral density of spinal bone, it also prevents the damage of oxidation cause of pulmonary hypertension and respiratory distress syndrome, according to the study of "Cell-specific expression of manganese superoxide dismutase protein in the lungs of patients with respiratory distress syndrome, chronic lung disease, or persistent pulmonary hypertension" by Asikainen TM, Heikkilä P, Kaarteenaho-Wiik R, Kinnula VL, Raivio KO., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/11536448)
6. Constipation
Dietary fiber helps to increase the size and soften the stool, thus reducing the risk of constipation, according to the study of "A dietary fiber mixture versus lactulose in the treatment of childhood constipation: a double-blind randomized controlled trial" by Kokke FT, Scholtens PA, Alles MS, Decates TS, Fiselier TJ, Tolboom JJ, Kimpen JL, Benninga MA., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/18979582). Since it is hard to digest, it makes out stomach feeling full longer, resulting in weight loss, according to the study of 'Whole-grain ready-to-eat oat cereal, as part of a dietary program for weight loss, reduces low-density lipoprotein cholesterol in adults with overweight and obesity more than a dietary program including low-fiber control foods" by Maki KC, Beiseigel JM, Jonnalagadda SS, Gugger CK, Reeves MS, Farmer MV, Kaden VN, Rains TM., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/20102847)

7. Etc.

Side effects
1. Oxalation
Oxalates can become too concentrated in body fluids, if eaten in large amount.
2. Etc.

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Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/20178390
(b) http://www.ncbi.nlm.nih.gov/pubmed/20218618
(c) http://www.ncbi.nlm.nih.gov/pubmed/21831414
(d) http://www.ncbi.nlm.nih.gov/pubmed/21045162
(e) http://www.ncbi.nlm.nih.gov/pubmed/18684235
(1) http://www.ncbi.nlm.nih.gov/pubmed/19160185
(2) http://www.ncbi.nlm.nih.gov/pubmed/20713332
(3) http://mi.rsmjournals.com/content/17/1/19.abstract
(4) http://www.ncbi.nlm.nih.gov/pubmed/21967159
(5) http://www.ncbi.nlm.nih.gov/pubmed/21951617

#Healthy Foods - Aarden Strawberries (Fragaria × ananassa)



Strawberries
Strawberries is a genius of Fragaria × ananassa belongs to the family Roseaceae. They have been grown all over the world with suitable climate for commercial profits and for health benefits.

Nutritional supplements1. Carbohydrate
2. Dietary fiber
3. Omega 3 fatty acid
4. Calcium
5. Iron
6. Magnesium
7. Phosphorus
8. Potassium
9. Sodium
10. Zinc
11. Copper
12. Manganese
13. Selenium
14. Vitamin C
15. Thiamin
16. Niacin
17. Pantothenic acid
18. Vitamin B-6
19. Folate
20. Vitamin B-12
21. Vitamin A
22. Vitamin E
23. Vitamin K
24. Etc.

Health benefits
A. Health benefits according to studies
1.
Atherosclerosis
In the investigation of Strawberries and its antioxidants and reduce cardiovascular risk effects found that short-term freeze-dried strawberry supplementation improved selected atherosclerotic risk factors, including dyslipidemia and circulating adhesion molecules in subjects with metabolic syndrome, and these results need confirmation in future trials. according to "Strawberries decrease atherosclerotic markers in subjects with metabolic syndrome" by Basu A, Fu DX, Wilkinson M, Simmons B, Wu M, Betts NM, Du M, Lyons TJ.(a)

2.
Lipid peroxidation
In the evaluation of Strawberry flavonoids and its anti-inflammatory effect found that Total cholesterol and LDL-cholesterol levels were significantly lower at 4 weeks versus baseline (-5% and -6%, respectively, p < 0.05), as was lipid peroxidation in the form of malondialdehyde and hydroxynonenal (-14%, p < 0.01). Oxidized-LDL showed a decreasing trend at 4 weeks (p = 0.123). No effects were noted on markers of inflammation including C-reactive protein and adiponectin. A significant number of subjects (13/16) showed an increase in plasma ellagic acid at four weeks versus baseline, while no significant differences were noted in dietary intakes at four weeks versus baseline. Thus, short-term supplementation of freeze-dried strawberries appeared to exert hypocholesterolemic effects and decrease lipid peroxidation in women with metabolic syndrome., according to "Freeze-dried strawberry powder improves lipid profile and lipid peroxidation in women with metabolic syndrome: baseline and post intervention effects" by Basu A, Wilkinson M, Penugonda K, Simmons B, Betts NM, Lyons TJ.(b)

3.
Human health
In the
review and update of the current knowledge on the potential impact of strawberry on human health, found that the mechanisms responsible for the potential health-promoting effects of strawberry may not be necessarily searched in the activity of phytochemicals. Particularly, a greater interest should be addressed to show whether a prolonged strawberry consumption may effectively improve the folate status and reduce the incidence of folate-related pathological conditions. Furthermore, the hypouricaemic effects of cherries need to be evaluated also in respect to strawberry intake, and the mechanisms of actions and anti-gout potentialities need to be studied in detail. Future investigations involving human trials should be aimed at following these underestimated scientific tracks, according to "Impact of strawberries on human health: insight into marginally discussed bioactive compounds for the Mediterranean diet" by Tulipani S, Mezzetti B, Battino M.(c)

4. A
ntioxidant enzymes
In the identification of essential nutrient and beneficial phytochemicals of strawberry and their effects on gastrointestinal disorders such as gastric ulcer, colorectal cancer and inflammatory bowel disease found that Strawberry extracts prevented exogenous ethanol-induced damage to rats' gastric mucosa. These effects seem to be associated with the antioxidant activity and phenolic content in the extract as well as with the capacity of promoting the action of antioxidant enzymes. A diet rich in strawberries might exert a beneficial effect in the prevention of gastric diseases related to generation of reactive oxygen species, according to "Strawberry polyphenols attenuate ethanol-induced gastric lesions in rats by activation of antioxidant enzymes and attenuation of MDA increase" by Alvarez-Suarez JM, Dekanski D, Ristić S, Radonjić NV, Petronijević ND, Giampieri F, Astolfi P, González-Paramás AM, Santos-Buelga C, Tulipani S, Quiles JL, Mezzetti B, Battino M.(d)

5. Anti inflammation
In the observation of Ethanolic extract of Fragaria vesca (EFFV) of Fragaria vesca L. and its effect on Ulcerative colitis and Crohn's disease (chronic recurrent inflammatory bowel disease (IBD)) found that EFFV at 500 mg/kg showed significant amelioration of experimentally induced IBD, which may be attributed to its antioxidant and anti-inflammatory properties, according to "Effect of fruit extract of Fragaria vesca L. on experimentally induced inflammatory bowel disease in albino rats" by Kanodia L, Borgohain M, Das S.(e)

6. Etc.

B. Health benefits according to concentration
1. Vitamin C
In the evaluation of pulmonary dysfunction. and it effects on pulmonary dysfunction found that At present, evidence from randomised-controlled trials is insufficient to recommend a specific role for vitamin C in the treatment of asthma. Further methodologically strong and large-scale randomised controlled trials are needed in order to address the question of the effectiveness of vitamin C in children with asthma but some outcome data showed effectiveness on lung function, symptom scores, IgE levels and inhaled steroid use. One small study showed a significant difference in % drop in FEV1 post-exercise, according to the study of "Vitamin C supplementation for asthma" by Kaur B, Rowe BH, Arnold E.(1)

2. ManganeseIt is one of important trace in preventing osteoporosis, according to the study of "[Study of estrogen deficiency impact on manganese levels in teeth and mandible of rats after ovariectomy]. [Article in Polish]" by Rahnama M, Błoniarz J, Zareba S, Swiatkowski W.(1)and regulating blood sugar level, according to the study of "[An inadequate intake of manganese may favour insulin resistance in girls]. [Article in Spanish]" by Rodríguez-Rodríguez E, Bermejo LM, López-Sobaler AM, Ortega RM.(2)

3. Dietary fiberDaily intake of right amount of fibers can prvent and treata. Diabetes, as Increased consumption of vegetables, whole grains, and soluble and insoluble fiber is associated with improved glucose metabolism in both diabetic and nondiabetic individuals. Improvements in insulin sensitivity and glucose homeostasis were more evident in participants following a plant-based diet compared with other commonly used diets, according to the study of "Efficacy of high-fiber diets in the management of type 2 diabetes mellitus" by Wolfram T, Ismail-Beigi F.(3)

4. FolateIn the investigation of the prevalence and multifactorial etiology of anemia among Indian human immunodeficiency virus (HIV)-infected children and its effect on anemia, found that Anemia, particularly iron deficiency anemia and anemia of inflammation, is highly prevalent among children with HIV infection. Micronutrient supplements (iron and, folate) combined with ART(antiretroviral therapy) improved anemia in HIV-infected children, according to "The prevalence and etiology of anemia among HIV-infected children in India" by Shet A, Arumugam K, Rajagopalan N, Dinakar C, Krishnamurthy S, Mehta S, Shet AS.(4)

5. Etc.
C. Other health benefits
1. Common cold and hear diseases
Vitamin C is best known for its function in preventing and treating of common cold, according to the study of "Vitamin C for preventing and treating the common cold" by Douglas RM, Hemilä H, Chalker E, Treacy B., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/17636648)and as a powerful antioxidant, it not only promotes the immune system in protecting our body, but also improves the capillary from breaking off, thus reducing the risk of heart diseases and stroke, according to the study of "Effect of long-term treatment with antioxidants (vitamin C, vitamin E, coenzyme Q10 and selenium) on arterial compliance, humoral factors and inflammatory markers in patients with multiple cardiovascular risk factors" by Shargorodsky M, Debby O, Matas Z, Zimlichman R., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/20604917) researchers found that Antioxidant supplementation significantly increased large and small artery elasticity in patients with multiple cardiovascular risk factors. This beneficial vascular effect was associated with an improvement in glucose and lipid metabolism as well as decrease in blood pressure.
2. information transmitting of the nerve cell
Manganese is found mostly in your bones, kidneys, liver and pancreas, manganese acts as coenzymes to assist our body in biochemical transformations, especially in promoting the information transmitting of the nerve cells, according to the study of "Role of manganese in neurodegenerative diseases" by Bowman AB, Kwakye GF, Herrero Hernández E, Aschner M.,posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/21963226)
3. Waste removal
Fiber beside improves the function of the large intestine in stool removal, it also helps to release the glucose slowly into blood stream, thus reducing the stress of pancreas in insulin production, thus reducing the risk of type II diabetes, according to the study of "Efficacy of high-fiber diets in the management of type 2 diabetes mellitus" by Wolfram T, Ismail-Beigi F., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/20713332)
4. Iodine
Iodine is essential to enhance the production of tyrosine-based hormones - thyroxine(T4) and triiodothyronine (T3), thus increasing the function of thyroid in regulating the growth and development of the body and protecting against hyper and hypo-thyroidism, according to the article of "Thyroid Regulation" posted in Life Extension.
5. Potassium
This mineral is vital for nerve cells of the brain in enhancing the transmitting information between themselves and cells in the body, according to the article of "Potassium In Foods" By Shereen Jegtvig, About.com Guide, Updated October 08, 2011, posted in About.com
6. Breast cancer
Folate or vitamin B12 is important in prevent the forming breast cancer, according to the article of "Folate, Vitamin B6 Fight Breast Cancer" posted in WebMD, the writer wrote that women with the highest folate levels were 27% less likely to have breast cancer than those with the lowest folate levels.

7. Etc.
Side effects
1. Some people experience anaphylactoid reaction to the consumption of strawberries
2. Oxalation
Oxalates in high concentration can cause problem for people with kidney diseases.
3. Etc.

Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve 
Optimal Health And Loose Weight

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