Kyle J. Norton
Celery may be used as natural food therapy in reducing symptoms of acute and chronic painful or inflammatory conditions, such as arthritis.
According to a recent study, Celery Seed Extract (CSE) has been found to be more effective in comparison to aspirin, ibuprofen, and naproxen in suppressing arthritis symptoms in a model of polyarthritis without interaction with compared medication intake.
Dr. Powanda MC, the lead researcher said, "Unlike many dietary supplements, the available data suggest that CSE does not significantly affect the p450 enzyme systems( function in interaction with medication intake) and thus is less likely to alter the metabolism of drugs the individual may be taking"
Celery is a species of Apium graveolens, belonging to the family Apiaceae, cultivated all around the globe as a vegetable. Celery can grow to 1/2 m tall with stalks (leaf on the top) arranged in a conical shape joined at a common base.
The over-the-counter (OTC) oral remedies for arthritis and rheumatism classified celery seed extracts have an effective efficacy as ibuprofen in the anti-arthritic assay without causing gastric bleeding, but the treatment ranged from almost zero to highly effective depending on a certain class of product.
In support of the above differentiation, A. graveolens (AGE) against liver oxidative stress in an adjuvant-induced arthritic rat model study found that oral administration of AGE (250, 500, and 1,000 mg/kg) for 24 consecutive days in the rat model, reduced symptoms of arthritis through reduced liver oxidative stress and enhanced liver antioxidant properties.
Taking it all together, the intake of celery may be effective in ameliorated symptoms of arthritis through binding to the expression of proinflammation cytokines. But oral administrated a large number of celery supplements such as celery seed should be consulted with related field specialists.
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Sources
(1) Celery Seed and Related Extracts with Antiarthritic, Antiulcer, and Antimicrobial Activitie by Powanda MC, Whitehouse MW, Rainsford KD. (PubMed)
(2) Over-the-counter (OTC) oral remedies for arthritis and rheumatism: how effective are they? by Whitehouse MW1, Roberts MS, Brooks PM. ( PubMed)
(3) Effects of Apium graveolens Extract on the Oxidative Stress in the Liver of Adjuvant-Induced Arthritic Rats bySukketsiri W1, Chonpathompikunlert P2, Tanasawet S3, Choosri N1, Wongtawatchai T3.(PubMed)
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