Inflammation is a natural response of the immune system to protect our body against injury and damage-induced infection.
Black bean, a small roughly ovoid legume with glossy black shells, genus Phaseolus, belongings to the family Fabaceae can be bought in most grocery stores all around the year in dried and canned forms. It is believed that the black bean was the first domesticated growth in South America.
Black or common beans with abundant phytochemicals may be considered functional foods in attenuated pro-inflammatory expression induced by immunity during injured, a respectable institute postulated.
In a randomized, controlled, crossover trial of 12 adults with metabolic syndrome (MetS) who consumed one of three meals (black bean (BB), fiber matched (FM), and antioxidant capacity matched (AM)) study, researchers found that blood sample collection before (fasting) and five hours after the meal, black bean intake group showed a significant expression of plasma antioxidant capacity and inflammatory cytokines in response to meals differences over time.
This result showed strong support for black bean intake reduced levels of oxidative stress-induced inflammation and enhanced production of antioxidants.
Dr. Reverri EJ the lead researcher said, " Inclusion of black beans with a typical Western-style meal attenuates postprandial insulin and moderately enhances postprandial antioxidant endpoints".
In other words, adding a portion of black bean may improve insulin resistance and induce antioxidant activity to modify the risk and treatment of inflammatory metabolic syndrome.
In colon inflammation triggered by high-fat diet (HD)-induced obesity in mice, mice fed with black bean showed a remarkable effect in a reduced pro-inflammatory expression such as tumor necrosis factor (TNF)-α, interleukin (IL)-1β, and IL-6, by attenuating changes associated with HD-induced colon inflammation.
Additionally, black bean-fed mice also demonstrated a significant improvement of antioxidants through modulated colon mRNA expression and reduced macrophage infiltration into adipose tissue, causing inflammation.
Furthermore, Dr. the lead author expressed, " BAB ameliorates HD-induced disorders such as obesity and colitis by improving mucosal barrier protection and reducing endotoxemia, as well as by inactivating NF-κB to decrease the production of proinflammatory cytokines".
Another study in support of the efficacy of black beans in ameliorated inflammation suggested that bean diets reduced not only mRNA expression of exhibited production of colonic inflammatory cytokines (IL-6, IL-9, IFN-γ, and IL-17A) and increased anti-inflammatory IL-10 (P< 0·05), but also systemically reduced circulating cytokines (IL-1β, TNFα, IFNγ, and IL-17A, P< 0·05) and dextran sodium sulfate-induced oxidative stress and colitis in animal model.
The findings suggested that black beans may be used as a functional food for the prevention of inflammation after body injury or damage by reduced levels of pro-inflammatory and increased levels of anti-inflammatory cytokines.
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(1) Black Beans, Fiber, and Antioxidant Capacity Pilot Study: Examination of Whole Foods vs. Functional Components on Postprandial Metabolic, Oxidative Stress, and Inflammation in Adults with Metabolic Syndrome by Reverri EJ1, Randolph JM2, Steinberg FM3, Kappagoda CT4, Edirisinghe I5, Burton-Freeman BM6,7.(PubMed)
(2) Black Adzuki Bean (Vigna angularis) Attenuates High-Fat Diet-Induced Colon Inflammation in Mice by Yook JS1, Kim KA2, Kim M1, Cha YS1.(PubMed)
(3) Cooked navy and black bean diets improve biomarkers of colon health and reduce inflammation during colitis by Zhang C1, Monk JM1, Lu JT1, Zarepoor L1, Wu W1, Liu R1, Pauls KP2, Wood GA3, Robinson L4, Tsao R1, Power KA1. (PubMed)
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