Tuesday, 8 August 2023

#Amine Oxidase Found in #Green Pea (GP) Inhibits the Risk of #AllergicAsthma, Researchers Say

Kyle J. Norton

Respiratory disease is a class of medical conditions that affect the breathing organ and tissues. The most common respiratory diseases are inflammatory lung disease, obstructive lung disease, restrictive lung disease, and respiratory tract infections.
Asthma is a chronic inflammatory disease affecting the airway of the lung with recurring symptoms, such as wheezing, chest tightness, shortness of breath, and coughing.

The medical condition affects people of all ages and mostly starts during childhood.

Besides episodes of wheezing, coughing, chest tightness, and shortness of breath, patients with asthma also experience symptoms of reversible airflow obstruction and bronchospasm.

Asthma attack in most cases is triggered by exposure to various irritants and substances that trigger allergies (allergens). However, genetic preposition and family history are also found in patients with asthma.

Asthma in some cases can interfere with daily activities and may lead to a life-threatening asthma attack. Treatment of asthma is to reduce the frequent episode and severity of the attacks.

According to the statistics provided by the Centers for Disease Control and Prevention (CDC), in the US, 1 in 13 people have asthma. In other words, over 26 million Americans have asthma and half of that is children.

Allergic asthma is the most common form of asthma, triggered by inhaling allergens such as dust mites, pet dander, pollen, or mold.

The condition, in most cases, is involved in the overreaction of the immune system against unharmful allergens, leading to the tightening of the muscle of the airway.

Green peas are species of Pisum Sativum belongings to the family Fabaceae and native to western Asia from the Mediterranean Sea to the Himalayas Mountains. The pea is a green, pod-shaped vegetable and a cool-season crop grown in many parts of the world.

In finding a potent ingredient for the treatment of asthma, researchers investigated the impact of amine oxidase green pea (GP) effects on allergic asthma shock.

According to the tested analysis, the plant amine oxidase (Cu-AO, histaminase, EC1.4.3.6) purified from pea seedlings showed strong activity against the onset of allergic asthma by modulating IgE-mediated allergic reactions.

Where the IgE antibodies formed to an antigen (or allergen) are determined by many factors including genetic, flea, food, and environmental allergens.

In other words, plant amine oxidase purified from pea seeding mediates the hypersensitive response of immune functioning against allergic asthma shock.

Taken together, green peas may be considered a functional food for the prevention of allergic asthma, pending the confirmation of the larger sample size and multicenter human study.



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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Pea seedling histaminase as a novel therapeutic approach to anaphylactic and inflammatory disorders. A plant histaminase in allergic asthma and ischemic shock by Masini E1, Bani D, Marzocca C, Mateescu MA, Mannaioni PF, Federico R, Mondovì B. (PubMed)

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