Hormone Therapy: Progesterone in Reduced Risk of Pre Term Birth

By Kyle J. Norton

Women with history of pre mature birth may be benefits from injection of hormone progesterone to reverse the incidence of recurrence, a renowned institute study suggested,

Progesterone is a steroid hormone, produced by the women body to regulate part of the menstrual cycle and supporting the gestation and the process of sperm in egg fertilization.

Preterm birth is a term for any infant born less than 37 weeks gestational age.

According to the joint study lead by the Universitätsklinikum Heidelberg, progesterone has a profound effect in protect the cervix in strengthen the layers of the uterine wall, reduced the myometrial contractility and inhibited the production of pro inflammatory cytokins.

In the review of literature of database from PubMed published from 1956 to August 2014, women with previous preterm birth incidience received vaginal progesterone daily (200 mg capsule or 90 mg containing gel) at from 16+0 to 36+0 weeksm showed a significant improvement in reduced risk of preterm incidence and infant mortality.

The same term of progesterone injected to women with short cervix also benefits in attenuated risk of preterm birth <28, <33, and <35 weeks of gestation.

Unfortunately, progesterone therapy showed inconclusive evidences as maintenance therapy after arrest of preterm labor.

Dr. Kuon RJ, the lead author said, " The vaginal administration of progesterone is well-tolerated by the patients and has only minor maternal side effects".

Other researchers in the finding of pre term incidience suggested that a short cervix may be a clinically silent sonographic in the midtrimester in induced pre term accident. Injection of  vaginal progesterone showed a huge improvement in reduced rate of preterm delivery by 45% as well as the rate of neonatal morbidity.

According to the study, the hormone therapy substantially decrease rate of spontaneous preterm birth with a short cervix in both women with and without a prior history of preterm birth in compared to conventional medicine 17α-Hydroxyprogesterone caproate.

In support to the above analysis, a reviewed analysis of 36 randomised controlled trials (8523 women and 12,515 infants) indicated that progesterone treatment for women with a past history of spontaneous preterm birth showed a statistically significant reduction in the risk of perinatal mortality in compared to placebo, particular in the risk of preterm birth less than 34 weeks' gestation.

In compared to placebo, the study also found that progesterone therapy addressed a significant reduction in the risk of infant birthweight less than 2500 g in other risk factors not related to history and short cervix.

Taking altogether, application of hormone progesterone showed a increadible result in reduced risk of preterm birth between 28  - 34 weeks of gestation in both women with or without previous history of preterm  incidence.

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You Can Eliminate Osteoarthritis
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Impact In Rice, Pasta, And Potatoes In Half

Author biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Source

(1) [Progesterone for Prevention of Preterm Birth--Evidence-based Indications]. [Article in German] by Kuon RJ1, Abele H2, Berger R3, Garnier Y4, Maul H5, Schleußner E6, Rath W7; Experts for the Prediction and Prevention of Preterm Birth (X4PB) – www.x4pb.de.(PubMed)
(2) Progesterone to prevent spontaneous preterm birth by Romero R1, Yeo L2, Chaemsaithong P2, Chaiworapongsa T2, Hassan SS2.(PubMed)
(3) Prenatal administration of progesterone for preventing preterm birth in women considered to be at risk of preterm birth by Dodd JM1, Jones L, Flenady V, Cincotta R, Crowther CA.(PubMed)

 

Food Therapy: Kidney beans( Phaseolus), The Best Function Food for Reduced Risk and Treatment of Chronic Diseases

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


The use of plants for healing purposes has been predated long before the existence of  modern medicine. Herbal plants have formed a fundamental source for conventional medicine in discovery of single ingredient medication, including aspirin (from willow bark), quinine (from cinchona bark), and morphine (from the opium poppy)......

Recent study suggested regular intake of kidney bean may be beneficial in the prevention and treatment of chronic diseases.
Kidney bean is popular because of its kidney shape, strong flavor and color of reddish brown in nature.  The bean often is an excellent dietary selection with no cholesterol, but a good source of protein and minerals.

Chronic disease is a medical condition last more than 3 months or more and can not be cured.

According to the University of Colorado Colorado Springs, consumption of kidney bean regularly  attenuated the increased glycaemic stress (hyperglycaemia and hyperinsulinaemia) including diabetes, CVD and cancer.

Dr. Hutchins AM, the lead author said, " (The efficacy of kidney in reduced risk of chronic illness may be attributed to the) glycaemic response and the impact that relationship may have on the risk of developing diabetes, CVD and cancer".

In the study to compared two different illumination conditions during germination (12 h light/12 h dark vs 24 h dark) in lentils (Lensculinaris L.) and kidney beans (Phaseolus vulgaris L.), melatonin content exerted a significantly antioxidant activity in protection against free radicals as well as showing the use of food as  preventive strategies in combating chronic diseases through the diet.

Furthermore, the investigation of phenolic rich extracts obtained from two kinds of common beans, white kidney beans (WKB) and round purple beans (RPB), extracts Phenolic acids and phenolic compounds expressed a strong antioxidants and anti inflammatory activities in reduced the incidence of several chronic diseases that share an inflammatory component.

Dr. García-Lafuente A, the lead researcher in the study said, "common bean extracts may be used as a source of anti-inflammatory agents as well as a dietary complement for health promotion".

Taking together, intake kidney beans regularly may reduce risk and progression chronic illness through the immunomodutory effects involved increased antioxidant and ameliorated inflammatory activities.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half  

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) Phaseolus beans: impact on glycaemic response and chronic disease risk in human subjects by Hutchins AM1, Winham DM, Thompson SV.(PubMed)
(2) Effect of illumination on the content of melatonin, phenolic compounds, and antioxidant activity during germination of lentils (Lens culinaris L.) and kidney beans (Phaseolus vulgaris L.) by Aguilera Y1, Liébana R, Herrera T, Rebollo-Hernanz M, Sanchez-Puelles C, Benítez V, Martín-Cabrejas MA.(PubMed)
(3) In vitro anti-inflammatory activity of phenolic rich extracts from white and red common beans by García-Lafuente A1, Moro C2, Manchón N2, Gonzalo-Ruiz A3, Villares A2, Guillamón E2, Rostagno M2, Mateo-Vivaracho L2.(PubMed)

Food therapy: Intake of Coffee Caffeine > 300mg/day Increased Risk of Delay Conception

By Kyle J. Norton


In compared to herbal medicine, food therapy even takes longer to ease symptoms, depending to stage of the treatment which directly addresses to the cause of disease.

Caffeine found in coffee consumption may increase risk of delayed conception depending to amount of caffeine intake per day, a renowned European institute study suggested.

Infertility is defined as inability of a couple to conceive after 12 months of unprotected sexual intercourse or can not carry the pregnancy to full term. It effects over 5 millions couple alone in the U. S. and many times more in the world.

Coffee, becoming a popular and social beverage all over the world, particular in the West, is a drink made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.

In a collected retrospectively on time of unprotected intercourse for the first pregnancy of a randomly selected sample of 3,187 women aged 25-44 years from five European countries (Denmark, Germany, Italy, Poland, and Spain) between August 1991 and February 1993, women drinking more than 500 mg of caffeine per day,  showed significantly increased odds ratio (OR) of 1.45, in risk of delay first pregnancy, in compared to women who consumed less than the maximum amounts.

The study also mentioned that, fertile women who are smokers and consumes over 500mg caffeine per day are associated higher related risk of 1.56 in compared to non smokers with same amounts of caffeine intake,

In first pregnancy, maximum or over maximum amounts of caffeine intake showed an increased time of waiting by 11%..

Other, in the examine of the retrospective study of 1,430 non-contracepting, parous women interviewed between July 1989 and June 1990 at Fishkill, New York, and Burlington, Vermont. and 2,501 pregnancies since 1980. Women's reported consumption of caffeinated beverage during the first month of pregnancy, range of daily caffeine intake of none, 1-150, 151-300, and > or = 301 mg with women who did not smoke and who consumed no caffeine used as a reference group, we found that women who drank none to 300 mg of caffeine showed a same relative risk of  in delay of conception among nonsmokers in compared to reference group.

Women, who do not smoke, intake more than 300 mg caffeine, showed a significantly increased delay conception odd ratio of 2,65.

Dr. Stanton CK, the lead author said, "Fecundability was reduced among nonsmokers who consumed more than 300 mg caffeine daily (fecundability ratio = 0.74, 95% CI 0.59-0.92)".

Interestingly, even though smoking reduced the ratio of delay conception, but caffeine consumption showed no effects on fecundability among women who smoked.

In support to the above differentiation, the Danish study also indicated that
nonsmoking women with a caffeine intake less than 300 mg/day in compared to nonsmoking women who consumed 300-700 mg/day of caffeine had a fecundability odds ratio (FR) of 0.88 against FR of 0.63 in higher consumption group.

The finding evidences suggested that women who want to get pregnant should reduce intake of caffeine to less than 300mg per day.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half

Author biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Caffeine intake and delayed conception: a European multicenter study on infertility and subfecundity. European Study Group on Infertility Subfecundity by Bolúmar F1, Olsen J, Rebagliato M, Bisanti L.(PubMed)
(2) Effects of caffeine consumption on delayed conception by Stanton CK1, Gray RH.(PubMed)
(3) Caffeine intake and fecundability: a follow-up study among 430 Danish couples planning their first pregnancy by Jensen TK1, Henriksen TB, Hjollund NH, Scheike T, Kolstad H, Giwercman A, Ernst E, Bonde JP, Skakkebaek NE, Olsen J.(PubMed)

Herbal Therapy, Chaste Tree Berry, the Best Functional Food for Treatment of Female Sex Hormone Deficiency

By Kyle J. Norton

 Herbal medicine can only ease the symptoms of your illness gradually, depending to stages of the treatment which directly address to the causes of the disease.

A renowned institue study suggested that Chaste tree berry may be a functional food for treatment of female sex hormone deficiency.

Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of year as anaphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.

According to a joint study lead by the Ahvaz Jundishapur University of Medical Sciences, oral administrated Vitex agnus-castus fruit improved hypothalamic-pituitary-gonadal axis in regulation of the reproductive system and immune system in free radical scavenger activities involved natural aging, in a d-galactose induced aging model in female mice.

Mice injected with d-galactose (500 mg/kg/d for 45 days) in seventy-two female NMRI mice (48 3-month-old normal mice and 24 18-24-month-old mice), weighing 30-35 g randomly divided into six groups: control, Vitex, d-galactose, Vitex + d-galactose, Aging, and Vitex + Aging, groups treated with Chaste tree berry or combination with herbal medicine showed a strong effects in increased the levels of malondialdehyde (MDA), follicle-stimulating hormone, and luteinizing hormone.

Dr. Ahangarpour A, the lead researcher said, " Vitex can be suitable for some aging problems such as oxidative stress, female sex hormone deficiency, and an atrophic endometrium".

Further more, the testing of flavonoid glycosides, orientin and apigenin 3, 8-di-C-glycosides and iridoid compound, aucubin isolated from the ethanolic extract of Vitex agnus-castus fruits, also showed a significant increase in plasma progesterone and total estrogens levels and reduction in luteinizing and plasma prolactin hormones in two dose levels 0.6 and 1.2 g kg(-1) per body weight (b.w.).

Additionally, the study also found that the ethanolic extract induced significant increase in the uterine weight which showed an interaction of sexual hormone of progesterone and estrogen of ovariectomized rats at two dose levels comparable to that of control group.

Dr. Dr Jillian Stansbury, not the author of the above studies said,"Consumption of Vitex fruits by female chimpanzees as part of their natural diets has been found to dramatically increase progesterone levels in the urine, indicating an overall progesteronic effect.34 One hypothesis is that reduced LH allows follicle-stimulating hormone to dominate and can lead to decreased estrogen and testosterone and a relative increase in progesterone".

Taking together, in women, Chaste Tree Berry may have a strong effect in influence sex hormones

production in expression of antioxidant, anti aging and normalized hormone activities.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half  

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Effects of Vitex agnus-castus fruit on sex hormones and antioxidant indices in a d-galactose-induced aging female mouse model by Ahangarpour A1, Najimi SA2, Farbood Y3.(PubMed)
(2) Gynecological efficacy and chemical investigation of Vitex agnus-castus L. fruitsgrowing in Egypt by Ibrahim NA1, Shalaby AS, Farag RS, Elbaroty GS, Nofal SM, Hassan EM.(PubMed)
(3) WOMEN’S HERBS” FOR MEN By Editor1 Posted November 8, 2010
In Botanical Medicine, Endocrinology, Fertility, Men's Health, Nature Cure, Oncology, Dr Jillian Stansbury

Food Therapy: Coffee Adverse effect in Increased Risk of Iron Deficient Anemia

By Kyle J. Norton

In compared to herbal medicine, food therapy even takes longer to ease symptoms, depending to stage of the treatment which directly address to the cause of disease.

Coffee, a popular and social beverage all over the world, particular in the West, is a drink made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.

Dietary iron is an important mineral for our body to make oxygen-carrying proteins hemoglobin for red blood cells and myoglobin for muscle functioning as well as wide variety of metabolic processes, including oxygen and electron transport, deoxyribonucleic acid (DNA) synthesis......

Coffee may interfere digestive track function in absorbed nonheme iron from dietary sources, a respectable study suggested.

According to the lead author of the study, a cup of coffee intake showed to reduce iron absorption from a hamburger meal by 39%, in compared to 64% of tea, a potent inhibitor of iron absorption.

Even more interestingly, ingested a cup of drip coffee or instant coffee with a meal composed of semipurified ingredients, rate of iron absorption was reduced from 5.88% to 1.64 and 0.97%, respectively

In the time length basic, coffee exhibited same degree of iron inhibition regardless an hour before or after the meals. 

Furthermore, the authors also found that change of concentration of coffee intake may also interfere with rate of inhibition.

In the prevention of dietary consumption of induced iron deficiency, intake of  iron inhibited beverage such as tea and coffee are recommended to add iorn enhanced absorption foods into their diet such as ascorbic acid and meat, fish and poultry;... and reduced intake calcium.

Importantly, depletion of iron stores may only have minimum effect on enhanced iron absorption in people who follow an inadequate dietary situation, thus increased risk iron deficient anemia without even knowing it.

There is an algorithm established by the the University of Göteborg, to calculate the amount of iron absorption without injection of dietary enhancers and inhibitors, using basal dose absorption of 40% in compared to different amounts of dietary factors known to influence iron absorption by measuring iron absorption from 24 complete meals with mean iron absorption in 31 subjects served a varied whole diet labeled with heme- and nonheme-iron tracers over a period of 5 days.

However, researchers of the study also said, "This algorithm has several applications. It can be used to predict iron absorption from various diets, to estimate the effects expected by dietary modification, and to translate physiologic into dietary iron requirements from different types of diets".

The findings suggested that coffee may have inhibited effect in reduced digestive system functioning in absorption of dietary iron. Therefore, people with iron deficient anemia should take only coffee with an extra portion of iron enhancers in their meal.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half

Author biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Inhibition of food iron absorption by coffee by Morck TA, Lynch SR, Cook JD.(PubMed)
(2) Effect of tea and other dietary factors on iron absorption by Zijp IM1, Korver O, Tijburg LB.(PubMed)
(3) Prediction of dietary iron absorption: an algorithm for calculating absorption and bioavailability of dietary iron by Hallberg L1, Hulthén L.(PubMed)

Food Therapy: Beet, A Potent Attenuated Risk and Anti Skin Cancer Biomedical Whole Food

By Kyle J. Norton

In compared to herbal medicine; food therapy even takes longer to ease symptoms, depending to stages of the treatment which directly address to the cause of disease.

Skin caner is a medical condition characterized by abnormal skin cell growth in disordered and uncontrollable ways.

Beet, best known as the beetroot or garden beet and belonging to the amaranth family, is a perennial plant with leafy stems growing to 1–2 m tall.

Beet with high amount of organic nitrate may have a profound effect on risk factor and treatment of skin cancer.

According to the Howard University, in the analysis of beet root, anti skin cancer effect in vivo, measurement from bioassays indicated that beet root has a chemo preventive effect in expressed a significant inhibition on skin tumors of tested mice.

In skin tumor initiation with 390 nmol of 7,12-dimethylbenz(a)anthracene (DMBA) in 100 microl of acetone together with mouse skin tumor promotion with 3430 J/m(2) of ultraviolet light-B (UV-B), oral administration of 0.0025% and topical application of 390 nmol of betanin, the major chemical constituent isolated from beet root, revealed a strong protection in the mouse skin cancer model.

Beside skin cancer, betanin, a regularly consumed natural product colorant found abundance in beet root may also be effective chemopreventive agent in treating other types of cancer , such as lung and liver cancers.

Other in the validated sugar beet pectin/gelatin hydrogels, in vivo, conjunction with anti cancer chemodrug, doxorubicin, demonstrated a successfully suppressed growth of a solid tumor created by applied to skin of mouse melanoma B16F1 cells into nude mice. 

The findings reveal that beet, with high amounts of  nitrate may be used as therapeutic and functional food in attenuated risk and treatment of skin cancer alone or combined with other chemoagents. 

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Chemoprevention of lung and skin cancer by Beta vulgaris (beet) root extract by Kapadia GJ1, Tokuda H, Konoshima T, Nishino H.(PubMed)
(2) Chemoprevention of DMBA-induced UV-B promoted, NOR-1-induced TPA promoted skincarcinogenesis, and DEN-induced phenobarbital promoted liver tumors in mice by extract of beetroot by Kapadia GJ1, Azuine MA, Sridhar R, Okuda Y, Tsuruta A, Ichiishi E, Mukainake T, Takasaki M, Konoshima T, Nishino H, Tokuda H.(PubMed)
(3) Injectable and biodegradable sugar beet pectin/gelatin hydrogels for biomedical applications by Takei T1, Sugihara K, Yoshida M, Kawakami K.(PubMed)

Herbal Therapy: Andrographis, The Best Whole Herb for Reduced Risk and Treatment of Gastric/Stomach Cancer

By Kyle J. Norton


The use of plants for healing purposes has been predated long before the existence of  modern medicine. Herbal plants have formed a fundamental source for conventional medicine in discovery of single ingredient medication, including aspirin (from willow bark), quinine (from cinchona bark), and morphine (from the opium poppy)......

Scientists may have found a chemical constituent isolated from Andrographis paniculata, for reduced risk and treatment of gastric cancer, a respectable institute study suggested.

Andrographis paniculata is also known as Andrographis is a herbaceous plant, genus Andrographis, belonging to the family Acanthaceae, native to India and Sri Lanka, used in traditional Siddha and Ayurvedic in treating the common cold, flu, upper respiratory infections, infectious diseases, diarrhea, dysentery, cholera, pneumonia,....

Gastric/Stomach cancer is condition of abnormal growth of the mucus-producing cells of the inside lining of the stomach. Adenocarcinoma is the most common type of stomach cancer.

According to the joint study lead by the Chosun University, Andrographolide, a natural compound isolated from Andrographis paniculata, exerted a potentiated apoptosis and reduction of the ability of a cell to form clones triggered by recombinant human tumor necrosis factor of signaling systemic inflammation involved immune stimulation.

The study also found that Andrographolide enhances TRAIL(a protein functioning as a ligand in regulated the process of cell death)-induced apoptosis through interfering of cell division through a protein functioning involved the process of cell death and ROS generation in gastric cancer.

Dr. Lim SC, the lead author said, "Exposure of GC cells to andrographolide altered the expression level of several growth-inhibiting and apoptosis-regulating proteins, including death receptors".

Also in support of the analysis of the effects of Andrographis on gastric cancer, the First Affiliated Hospita study suggested, the effect of andrographolide on suppressed on adhesion of gastric cancer cells to the activated endothelial cells through blocking E-selectin(an antigen) expression in response to cancer cells in infiltrated the inflammatory system.

In three gastric cancer cell lines (SGC7901, MGC803, BGC823), with Andrographis significantly decreased gastric cancer cells adherence to stimulated endothelial cells by inhibited the E-selectin expression. through cytokins effect of the immune system.

Taking together, Andrographis paniculata may be used as a therapeutically promising product for reduced risk and treatment of gastric cancer, probably due to procession of Andrographolide, an active compound of the herb, but intake of large amount should only be prescribed by herbalist to avoid toxicity.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half  

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) [Advances in study on anti-tumor mechanism of andrographolide].[Article in Chinese] by Qi CL1, Wang LJ, Zhou XL.(PubMed)
(2) Andrographolide induces apoptotic and non-apoptotic death and enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in gastric cancer cells by Lim SC1, Jeon HJ1, Kee KH1, Lee MJ1, Hong R1, Han SI2(PubMed)
(3) Andrographolide inhibits the adhesion of gastric cancer cells to endothelial cells by blocking E-selectin expression by Jiang CG1, Li JB, Liu FR, Wu T, Yu M, Xu HM.(PubMed)