Tuesday 19 April 2016

Most Common Disease of 50+: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs)- Gout - Diseases associated with Gout - Heart diseases

Kyle J. Norton (Scholar and Master of Nutrients, all right reserved)Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(*).

Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                          Gout

Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in blood, inducing joint inflammation.

                                        Diseases associated with  Gout


According to the UK Gout Society,  diseases associated to gout may include
8. Heart diseases
Beside cancer, heart disease kills more than 2,000 Americans everyday. Approximately 60 million Americans have heart disease.  Most of heart diseases are caused by high blood pressure contributes to hardening of the arteries. High levels of bad cholesterol (LDL) build up in the arteries as a result of tuncontrolled diet with high levels of saturated fat and trans fat. According to study, risk of heart attached is increased in older women with gout(80).
In a total of 8,656,413 participants with a total of 1000 MI events included in the study conducted by Taizhou Municipal Hospital, patients with gout have an increased risk of myocardial infarction(81).
Recent studies conducted by some well known institutions suggested that the combination of Blueberry(82), Avocado(83) were found to have a potential effect for Reduced Risk and Treatment of Heart Disease. and recommended that People who are at increased of heart disease due to family history, obesity, gout.....should drink at least one serving daily and people with heart disease should drink no more than 4 servings a day, depending to digestive toleration.
Change of life style and diet pattern are also recommended(84).

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(80) Gout raises heart-attack risk in older women. Take steps to prevent this unexpected consequence.[No authors listed](PubMed)
(81) Gout and Risk of Myocardial Infarction: A Systematic Review and Meta-Analysis of Cohort Studies by Liu SC1, Xia L2, Zhang J1, Lu XH3, Hu DK1, Zhang HT4, Li HJ5.(PubMed)
(82) Blueberry Anthocyanins-Enriched Extracts Attenuate Cyclophosphamide-Induced Cardiac Injury. by Liu Y1, Tan D2, Shi L1, Liu X1, Zhang Y1, Tong C1, Song D2, Hou M1.(PubMed)
(83) Cardiovascular effects of Persea americana Mill (Lauraceae) (avocado) aqueous leaf extract in experimental animals by Ojewole JA1, Kamadyaapa DR, Gondwe MM, Moodley K, Musabayane CT.(PubMed)
(84) The Curable and Delicious smoothie of Blueberry, Avocado for Reduced Risk and Treatment of Heart Disease by Kyle J. Norton


Monday 18 April 2016

Most Common Disease of 50+: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Gout - Diseases associated with Gout - Obesity

Kyle J. Norton (Scholar and Master of Nutrients, all right reserved)Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(*).

Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                          Gout

Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in blood, inducing joint inflammation.

                                        Diseases associated with  Gout


According to the UK Gout Society,  diseases associated to gout may include
7.  Obesity
Obesity, one of the disease of metabolic syndrome is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height.
According to the joint study led by the Catholic University of Korea, gout is a chronic inflammatory disease the development of which is associated with obesity-induced metabolic abnormalities(72). And General obesity in women may potentiate an sUA effect for gout development in the study of a total of 261,500 person-years conducted by the China Medical University(73).
Recent studies conducted by some renowned institutions suggested that green tea(75)(76), avocado and(77) blueberry(78)979) may be a potent drink for reduced weight and treatment of overweight and obese subjects.
People who are at increased risk of overweight due to family history, gene mutation, .....should drink at least one serving daily and overweight and obese people should drink the smoothie as much as they can depending to digestive toleration.
Change of life style and diet pattern are also recommended(74).

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(72) Visceral fat obesity is highly associated with primary gout in a metabolically obese but normal weighted population: a case control study by Lee J1, Lee JY2, Lee JH3, Jung SM4, Suh YS5, Koh JH6, Kwok SK7, Ju JH8, Park KS9, Park SH10.(PubMed)
(73) Impact of obesity and hypertriglyceridemia on gout development with or without hyperuricemia: a prospective study by Chen JH1, Pan WH, Hsu CC, Yeh WT, Chuang SY, Chen PY, Chen HC, Chang CT, Huang WL.(PubMed)
(74) The Fabulous and Neverfailed smoothies of Green Tea, Avocado and Blueberry for Weight Loss by Kyle J. Norton
(75) The effects of green tea on weight loss and weight maintenance: a meta-analysis by Hursel R1, Viechtbauer W, Westerterp-Plantenga MS.(PubMed)
(76) Body weight loss and weight maintenance in relation to habitual caffeine intake and green tea supplementation by Westerterp-Plantenga MS1, Lejeune MP, Kovacs EM.(PubMed)
(77) The modulating effect of Persea americana fruit extract on the level of expression of fatty acid synthase complex, lipoprotein lipase, fibroblast growth factor-21 and leptin--A biochemical study in rats subjected to experimental hyperlipidemia and obesity by Monika P1, Geetha A2.(PubMed)
(78) Blueberry peel extracts inhibit adipogenesis in 3T3-L1 cells and reduce high-fat diet-induced obesity by Song Y1, Park HJ, Kang SN, Jang SH, Lee SJ, Ko YG, Kim GS, Cho JH.(PubMed)
(79) Blueberry and mulberry juice prevent obesity development in C57BL/6 mice by Wu T1, Tang Q, Gao Z, Yu Z, Song H, Zheng X, Chen W.(PubMed)






Most Common Disease of 50+: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Gout - Diseases associated with Gout - Diabetes

Kyle J. Norton (Scholar and Master of Nutrients, all right reserved)Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(*).

Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                          Gout

Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in blood, inducing joint inflammation.

                                        Diseases associated with  Gout


According to the UK Gout Society,  diseases associated to gout may include
6. Diabetes
Diabetes is a condition caused by insufficient insulin entering the bloodstream to regulate the glucose. It is either caused by cells in pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.
According to the University of Chicago, diabetic gout patients were older, more frequently female, and had longer gout duration(65).It is said that conventional treatment with 80 mg febuxostat may be more efficacious in female gout subjects with high rates of comorbidities in comparison of commonly prescribed doses of allopurinol(66).
Dr. Donath MY said, " an inflammatory process also seems to be involved in the development of cardiovascular, renal and ophthalmological complications of this disease. Interestingly, several other inflammatory diseases are associated with the metabolic syndrome(particular diabetes) such as psoriasis, gout and rheumatic arthritis"(67).

Recent studies back by renowned institution suggested that Cinnamon(69), Whole Food Papaya(70) and Green Tea(71) reduced Risk and Treatment of Diabetes through their effects in improved fasting blood glucose levels and glucose tolerance without altering the insulin secretion and in regulation of metabolism (carbohydrate, lipid, protein))-medicated glucose and lipid metabolism(68).

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(56) Prevalence of gout with comorbidity aggregations in southern Taiwan by Tu FY1, Lin GT2, Lee SS3, Tung YC4, Tu HP5, Chiang HC6.(PubMed)
(57) Lipid abnormalities in Taiwan aborigines with gout by Chou CT1, Chao PM.(PubMed)
(58) A Snack Dietary Pattern Increases the Risk of Hypercholesterolemia in Northern Chinese Adults: A Prospective Cohort Study by Na L1, Han T1, Zhang W1, Wu X1, Na G1, Du S1, Li Y1, Sun C1.(PubMed)
(59) Dietary supplementation contributes to lifestyle improvement in hypercholesterolemic patients in real-life contexts by Bruckert E1, Masana L, Chapman MJ, Descamps O, Bosi E, Allaert FA.(PubMed)
(60) [Studies on association between nonalcoholic fatty liver disease and hyperuricemia: current status and future prospects].[Article in Chinese] by Li YM1.(PubMed)


(65) Diabetes and gout: efficacy and safety of febuxostat and allopurinol by Becker MA1, MacDonald PA, Hunt BJ, Jackson RL.(PubMed)
(66) Women with gout: efficacy and safety of urate-lowering with febuxostat and allopurinol by Chohan S1, Becker MA, MacDonald PA, Chefo S, Jackson RL.(PubMed)
(67) Multiple benefits of targeting inflammation in the treatment of type 2 diabetes by Donath MY1.(PubMed)
(68) The Smoothie of Cinnamon, Whole Food Papaya and Green Tea reduced Risk and Treatment of Diabetes by Kyle J. Norton


Sunday 17 April 2016

Most Common Disease of 50+: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Gout - Diseases associated with Gout - Hypercholesterolemia

Kyle J. Norton (Scholar and Master of Nutrients, all right reserved)Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(*).

Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                          Gout

Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in blood, inducing joint inflammation.

                                        Diseases associated with  Gout



According to the UK Gout Society,  diseases associated to gout may include
4. Hypercholesterolemia
Unhealthy diet such as typical American diet with high in satyrated and trans fat and lower intake of vegetables and fruits has been found to associated to Hypertriglyceridemia and Hypercholesterolemia in epidemiological literature in data bases of PubMed(41)(42)(43).
Dr. Tu FY and colleagues of some well known institutions in Taiwan, according to the data from the Taiwan national health insurance database for 2004 to 2006, showed that hypercholesterolemia, were the common comorbidities of gout(56).
Furthermore, the association of gout and hypercholesterolemia may be due to poor quality of  life style implications(59) such as alcohol intake(57) as well as dietary low in vegetables and fruits(58)
Recent studies suggested that avocado(49)(50), Almond(51)(52) and green tea(53)(54) may consist a therapeutic values used combination for reduced risk and treatment of high blood cholesterol in patients with gout. 

For more information of above effectiveness, please visit, The Smoothie of avocado, Almond and green tea for prevention and treatment of Hyperlipidemia(High blood Cholesterol)(55).





References
(49) The modulating effect of Persea americana fruit extract on the level of expression of fatty acid synthase complex, lipoprotein lipase, fibroblast growth factor-21 and leptin--A biochemical study in rats subjected to experimentalhyperlipidemia and obesity by Monika P1, Geetha A2.(PubMed)
(50) Effect of Persea americana (avocado) fruit extract on the level of expression of adiponectin and PPAR-γ in rats subjected to experimental hyperlipidemia and obesity by Padmanabhan M, Arumugam G.(PubMed)
(51) Almonds inhibit dyslipidemia and vascular dysfunction in rats through multiple pathways by Jamshed H1, Gilani AH2.(PubMed)
(52) Statins and almonds to lower lipoproteins (the STALL Study). by Ruisinger JF1, Gibson CA2, Backes JM3, Smith BK4, Sullivan DK5, Moriarty PM6, Kris-Etherton P7.(PubMed)
(53) Green, oolong and black tea extracts modulate lipid metabolism in hyperlipidemia rats fed high-sucrose diet by Yang M1, Wang C, Chen H.(PubMed)
(54) Comparative studies on the hypolipidemic and growth suppressive effects of oolong, black, pu-erh, and greentea leaves in rats by Kuo KL1, Weng MS, Chiang CT, Tsai YJ, Lin-Shiau SY, Lin JK.(PubMed)
(55) The Smoothie of avocado, Almond and green tea for prevention and treatment of Hyperlipidemia(High blood Cholesterol) by Kyle J. Norton




Most Common Disease of 50+: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Gout - Diseases associated to- Hyperuricemia

Kyle J. Norton (Scholar and Master of Nutrients, all right reserved)Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(*).

Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                          Gout

Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in blood, inducing joint inflammation.

                                        Diseases associated with  Gout


According to the UK Gout Society,  diseases associated to gout may include
5. Hyperuricemia
Hyperuricemia, a condition with over expression of uric acid in the blood through liver most often found in patients with gout. According to Dr. Li YM. said, "It has been widely accepted that the increase in the level of uric acid significantly raises the risks of gout, cardiovascular disease, and type 2 diabetes."
It is acceptance epidemiological studies that high fruit and soybean products dietary intervention could be an effective alternative to a standard diet for achieving clinically important reductions in SUA for asymptomatic hyperuricemia patients(61). And major dietary patterns such as animal products and fried food are associated to risk of hyperuricemia(62).
According to the Chiang Mai University, green tea extract (GTE) also promoted hypouricemic and anti gout effects through modestly lowering serum uric acid (SUA) level and decreasing uric acid clearance(63). 
Reduced intake of food with rich purine, alcohol intake as well as controlling obesity and blood pressure, improving the status of lipid metabolic disorder together with programs as hypertension control etc.(64).




References
(61) Comparison of the effect of high fruit and soybean products diet and standard diet interventions on serum uric acid in asymptomatic hyperuricemia adults: an open randomized controlled trial BY Zhang M1, Gao Y2, Wang X1, Liu W3, Zhang Y3, Huang G1.(PubMed)
(62) Major dietary patterns and risk of asymptomatic hyperuricemia in Chinese adults by Zhang M1, Chang H, Gao Y, Wang X, Xu W, Liu D, Li G, Huang G.(PubMed)
(63) Effects of green tea extract on serum uric acid and urate clearance in healthy individuals by Jatuworapruk K1, Srichairatanakool S, Ounjaijean S, Kasitanon N, Wangkaew S, Louthrenoo W.(PubMed)
(64) [Epidemiological study on hyperuricemia and gout in Foshan areas, Guangdong province.][Article in Chinese] by Yu JW1, Yang TG, Diao WX, Cai XQ, Li T, Zhong H, Hu DL, Chen CQ, Chen ZX.(PubMed)


Saturday 16 April 2016

Most Common Disease of 50+: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Diseases associated with Gout - Hypertriglyceridemia

Kyle J. Norton (Scholar and Master of Nutrients, all right reserved)Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(*).

Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                          Gout

Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in blood, inducing joint inflammation.

                                        Diseases associated with  Gout


According to the UK Gout Society,  diseases associated to gout may include
3. Hypertriglyceridemia
Unhealthy diet such as typical American diet with high in saturated and trans fat and lower intake of vegetables and fruits has been found to associated to hypertriglyceridemia in epiodemilogical literature in data bases of PubMed(41)(42)(43), particular to hypertriglyceridemia in men(46).
In the searching of the association of hypertriglyceridemia in patients with gout, according to the Osaka University Medical School, there is a close correlation between the degree of uric acid production and triglyceride (TG) metabolism in 148 male subjects with primary gout(45).
Dr. Naito HK and Dr. Mackenzie AH. insisted, " diet and, possibly, defective clearance of triglycerides may be etiologic factors associated with the abnormal serum triacylglycerol (triglyceride) and lipoprotein concentrations in these individuals"(44).
According to the Korean National Health and Nutrition Examination Surveys (KNHANES) 2007-2009, supported the potential beneficial role of vegetables and fruits consumption to reduce blood triglyceride levels in Asian populations(47).
Furthermore, High-fat ketogenic diets, the only treatment available for Glut1 deficiency (Glut1D) as od today, according to joint study led by the Children's Hospital Aschaffenburg Alzenau after 3 years intake, showed a gradual increase of blood lipids, followed by rapid, severe asymptomatic hypertriglyceridemia (1,910 mg/dL)(48).

(41) Dietary Glycemic Index and Glycemic Load Are Positively Associated with Risk of Developing Metabolic Syndrome in Middle-Aged and Elderly Adults by Juanola-Falgarona M1,2, Salas-Salvadó J1,2, Buil-Cosiales P2,3, Corella D2,4, Estruch R2,5, Ros E2,6, Fitó M2,7, Recondo J2,8, Gómez-Gracia E2,9, Fiol M2,10,Lapetra J2,11, Lamuela-Raventós RM2,12, Serra-Majem L2,13, Pintó X2,14, Muñoz MA2,15, Ruiz-Gutiérrez V2,16, Alfredo Martínez J2,17, Castro-Quezada I2,13,Bulló M1,2; PREvencion con DIeta MEDiterranea Study Investigators.(PubMed)
(42) Lipemia retinalis: a combination of genetics and the American diet and lifestyle by Nogales SL1, Grimes AL, Song HF.(PubMed)
(43) Effect of lysine, vitamin B(6), and carnitine supplementation on the lipid profile of male patients withhypertriglyceridemia: a 12-week, open-label, randomized, placebo-controlled trial by Hlais S1, Reslan DR, Sarieddine HK, Nasreddine L, Taan G, Azar S, Obeid OA.(PubMed)
(44) Secondary hypertriglyceridemia and hyperlipoproteinemia in patients with primary asymptomatic gout by Naito HK, Mackenzie AH.(PubMed)
(45) Relationship between hypertriglyceridemia and uric acid production in primary gout by Matsubara K1, Matsuzawa Y, Jiao S, Takama T, Kubo M, Tarui S.(PubMed)
(46) Impact of obesity and hypertriglyceridemia on gout development with or without hyperuricemia: a prospective study by Chen JH1, Pan WH, Hsu CC, Yeh WT, Chuang SY, Chen PY, Chen HC, Chang CT, Huang WL.(PubMed)
(47) Fruit and vegetable consumption and hypertriglyceridemia: Korean National Health and Nutrition Examination Surveys (KNHANES) 2007-2009 by Yuan C1,2, Lee HJ3, Shin HJ1,4, Stampfer MJ1,2,5, Cho E5,6,7.(PubMed)
(48) Severe Hypertriglyceridemia in Glut1D on Ketogenic Diet by Klepper J1, Leiendecker B2, Heussinger N1, Lausch E3, Bosch F4.(PubMed)

Friday 15 April 2016

Most Common Disease of 50+: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs)- Diseases associated with Gout - Renal insufficiency

Kyle J. Norton (Scholar and Master of Nutrients, all right reserved)Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(*).

Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                          Gout

Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in blood, inducing joint inflammation.

                                        Diseases associated with  Gout


According to the UK Gout Society,  diseases associated to gout may include

2. Renal insufficiency
Patients with gout are associated to chronic kidney disease has been well documented in epidemiological literature(26). The joint study led by the Keele University suggested, "Chronic kidney disease and nephrolithiasis are commonly found amongst patients with gout. Gout is independently associated with both chronic kidney disease and nephrolithiasis. Patients with gout should be actively screened for chronic kidney disease and its consequences"(33).
Dr. Krishnan E said, "Chronic kidney disease manifesting as reduced glomerular function or as presence of blood or protein in the urine increases the risk of incident gout"(34).
Chronic Kidney disease is defined as a condition of the progression loss of kidney function over period of many years. Stage of chronic kidney disease according to the National Kidney Foundation's Kidney Disease Outcomes Quality Initiative (KDOQ). 

In the review of literature from data base of PubMed, Brazil Nut(35)(36), Flax Seed(37) and Honey(38)(39) found effectively in treatment of renal insufficiency back by recent studies from some well known institutions  may serve as cornerstones of pharmaceutical target for further studies as well as a potential medication for treatment of Chronic Kidney disease in patient with gout. For more information, please visit The Impossible Smoothie of Brazil Nut, Flax Seed and Honey For Prevention and Treatment of Chronic Kidney disease(40).

(33) Gout and risk of chronic kidney disease and nephrolithiasis: meta-analysis of observational studies by Roughley MJ1, Belcher J2, Mallen CD3, Roddy E4.(PubMed)
(34) Chronic kidney disease and the risk of incident gout among middle-aged men: a seven-year prospective observational study by Krishnan E1.(PubMed)
(35) A follow-up study of the chronic kidney disease patients treated with Brazil nut: focus on inflammation and oxidative stress by Stockler-Pinto MB1, Malm O, Moraes C, Farage NE, Silva WS, Cozzolino SM, Mafra D.(PubMed)
(36) Brazil nut (Bertholletia excelsa, H.B.K.) improves oxidative stress and inflammation biomarkers in hemodialysis patients. by Stockler-Pinto MB1, Mafra D, Moraes C, Lobo J, Boaventura GT, Farage NE, Silva WS, Cozzolino SF, Malm O.(PubMed)
(37) Patient with hypertriglyceridemia, type 2 diabetes, and chronic kidney disease treated with atorvastatin andomega-3 Fatty Acid ethyl esters by Athyros VG1, Mikhailidis DP.(PubMed)
(38) Honey: a novel antioxidant by Erejuwa OO1, Sulaiman SA, Ab Wahab MS.(PubMed)
(39) Randomized, controlled trial of topical exit-site application of honey (Medihoney) versus mupirocin for the prevention of catheter-associated infections in hemodialysis patients by Johnson DW1, van Eps C, Mudge DW, Wiggins KJ, Armstrong K, Hawley CM, Campbell SB, Isbel NM, Nimmo GR, Gibbs H.(PubMed)
(40) The Impossible Smoothie of Brazil Nut, Flax Seed and Honey For Prevention and Treatment of Chronic Kidney disease by Kyle J. Norton.