Posted By Kyle J. Norton
Health article writer and
researcher; Over 10.000 articles and research papers have been written
and published on line, including world wide health, ezine articles,
article base, healthblogs, selfgrowth, best before it's news, the karate
GB daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS &
AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters
Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such
as international journal Pharma and Bio science, ISSN 0975-6299.
Recipe contributed by Everything Busy Moms' Cook Book By Susan Whetzel Published by Adamsmedia. You can view its website at www.everything.com.
If you don't have left over cooked chicken and rice, you can get some
cooked chicken from your local deli and purchase cooked rice from any
Chinese takeout place.
Serves 4
Ingredients
2 cooked Chicken Breast
2 tablespoon olive oil
2 cups cooked Jasmin rice
1 cup frozen snap peas, thawed
and drained
1/3 cup apricot jam
2 tablespoons soy sauce
1/4 cup water
1. remove cooked meat from chicken; discard skin and bones. Cut chicken into 1-inch piece.
2. Heat olive oil in wok or heavy skillet. Add chicken and rice, stir
fry for 4-5 minutes until heated, stirring gently to separate rice
grains.
3. Add peas, jams, soy sauce, and water and stir-fry for 4-5 minutes
longer, until peas are hot and favors are blended. Serve immediately.
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Thursday 20 November 2014
Wednesday 19 November 2014
(Preview) Most common diseases of 50 plus - Thyroid Disease - Hypothyroidism : Preventions, Managements and Treatments
By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Thyroid disease
Thyroid disease is defined as a condition of malfunction of thyroid gland
Thyroid disease: Hypothyroidism
Hypothyroidism is a condition in which the thyroid gland is under active produced very little thyroid hormones.
A. Symptoms
Symptoms of the Hypothyroidism is depended to the severe stage of the disease, due to its progression slowly over years. Most common symptoms include
1. Weight gain and fatigue
Hyperthyroidism is associated to weight gain, especially in patients with co-existence of diabetes(1).
The comparable study of patients with thyroid carcinoma (DTC) and 138 with autoimmune hypothyroidism (AIH), also indicated a significantly higher levels of fatigue in hypothyroidism patients(1b). Statistics of study of 198 consecutive breast cancer patients receiving adjuvant chemotherapy, 22.2% of this patient population showed a significant and progressive weight gain of 6.7 lbs, and 94% of all patients with reported fatigue caused cytotoxic agents influence hypothyroidism in breast cancer patients(1a).
2. Vitiligo and alopecia areata
Vitiligo is associated with autoimmune endocrine disorders, especially with hypothyroidism(2). Primary hypothyroidism patients is at increased risk to develop vitiligo, depigmentation of parts of the skin and hair lost from some or all areas of the body, especially in the scalp(2a)
3. Chronic constipation(3a)
Hypothyroidism may induce the pathogenesis of constipation, according to the study by the University of California at Los Angele(3).
4. Urticaria and puffiness of hands and feet, yellow ivory skin, coarse rough dry skin
Hypothyroid women showed a significantly higher frequency of urticaria and puffiness of hands and feet, yellow ivory skin, coarse rough dry skin(4).
5. Depression
Patients with hypothyroidism have a higher occurrence of depressive syndrome, caused by alterations in blood flow and glucose metabolism in the brain(5).
6. Mood and motor learning
Oral administration of usual dose l-T(4) (euthyroid arm) vs. higher dose l-T(4) (subclinical thyrotoxicosis arm) , showed to improve confusion, mood and motor learning in patients with hypothyroidism(6).
B. Risk Factors and Causes
B.1. Risk factors
1. Family history
The risk of progression to overt hypothyroidism is related to number of factors including, family history(11a). Family members of patients with autoimmune thyroid disorder(AITD) are at increased risk for AITD, but not all will develop overt hypothyroidism or hyperthyroidism, according to the study by the Academic Medical Center, Netherlands(11).
2. Smoking
Smoking is a powerful risk factor for thyroid disease, especially in populations with a high smoking frequency, according to the study by the Aarhus University Hospital(12). Smoking reduced the risk of hypothyroidism but increased the risk of hypothyroidism in patients with Hashimoto's thyroiditis(13)(13a).
3. Age
Hypothyroidism is associated to increased age. In the old rat, the pituitary thyrotrophs increase hormonal secretion in response to decreased levels of thyroid hormones due to aging, even when the thyroid hormone levels are dramatically reduced, according to study of Dutch-Miranda and Wistar rats(14).
4. Autoimmune disorders, thyroid injury, post partum state, are common signs of patients with hypothyroidism, according to Dr. Zulewski H. at Universitätsspital Basel(15).
5. Radiation
Light microscopy, electron microscopy and immunohistochemical methods, can cause pathological changes in the thyroid gland throuigh altering the gland structure and enhancing apoptosis(16).
6. Post pregnancy
Women with autoimmune thyroiditis are associated to increase risk of hypothyroidism at 3-6 months post-partum(17).
7. Partial thyroidectomy
Partial thyroidectomy, a removal of part of thyroid gland induces overall prevalence of 16% of hypothyroidism(18).
B.2. Causes
1. Autoimmune response
Autoimmune disease is an over reaction of immune response of the body against substances and tissues normally presented in the body. Primary overt autoimmune hypothyroidism is divided into primary idiopathic hypothyroidism with thyroid atrophy (Ord’s disease) and hypothyroidism with goitre (Hashimoto’s disease)(7).
2. Congenital Hypothyroidism(CH)
Baby with postdate delivery and macrosomia are associated to increased risk od congenital hypothyroidism(8a).The incidence of CH was greater in our population for 2007 to 2010, after an unexplained decline, according to the study by the Columbia University Medical Center(8).
3. Pituitary disorder
Pituitary disorders, is associated to reduce or increase secretion of hormones, affected growth and the functions of other glands in the body. A normal TSH does not exclude central hypothyroidism, but pituitary disease, with potential for deficiency of other anterior pituitary hormones, may contribute to correctly diagnosed hypothyroidism(9).
4. Pregnancy
Women with TSH values at or above the 97.5th percentile for gestational age with free thyroxine more than 0.680 ng/dL at the time screening and were retrospectively identified with subclinical hypothyroidism, according to University of Texas Southwestern Medical Center(10).
2. Iodine deficiency
Iodine is a key element in the synthesis of thyroid hormones, severe iodine deficiency is associated to risks of hypothyroidism, goiter, and cretinism due to biochemical alterations, according to Verheesen RH and Schweitzer CM(11).
C. Complications
1. Coronary heart disease and mortality
Subclinical hypothyroidism is associated with an increased risk of the development of coronary heart disease (CHD). CHD mortality is higher in patients with diagnosed elevated TSH levels, particularly in those TSH concentration of 10 mIU/L or greater(19).
2. Pre-eclampsia, perinatal mortality, and miscarriage
Thyroid dysfunction interferes with women reproductive physiology, reduces the likelihood of pregnancy and adversely affects pregnancy outcome. According to the study by the MGM Medical College, pregnant women with subclinical hypothyroidism has an increased risk of complications, especially pre-eclampsia, perinatal mortality, and miscarriage(21).
3. Ovulatory dysfunction, pregnancy loss
Subclinical hypothyroidism may be associated with ovulatory dysfunction and adverse pregnancy outcome(22).
4. Increased susceptibility to inflammatory diseases
Hypothyroidism during gestation can influence the outcome of a CNS inflammatory disease, such as EAE, according to the study by the Universidad Andres Bello, Ciencias Biologicas(23).
5. Auditory function
Iodine deficiency may contribute auditory function (deaf and hard of hearing) in process information. Hearing deficit, an invisible abnormality, has major consequences for educational and social skills if not detected, according to the study by the Wageningen University, Wageningen(24).
6. Hearing loss
Hearing loss contribute a significant problem, in adult patients with severe chronic hypothyroidism(25).
D. Diseases associated to hypothyroidism
1. Systemic Sclerosis
Systemic sclerosis (SSc) is a connective tissue disease of unknown etiology, and several studies reported its association with thyroid autoimmune disorders, including hypothyroidism and thyroid dysfunction(26).
2. Osteoarthritis and fibromyalgia
Thyroid dysfunction is seen at least three times more often in women with RA than in women with similar demographic features with non-inflammatory rheumatic diseases such as osteoarthritis and fibromyalgia(27).
3. Type 1 diabetes mellitus (T1DM)
8% of patients with T1DM had hypothyroidism, according to the data presented to department of Endocrinology from May 1997 to December 2011(28).
4. Adrenal insufficiency
According to study, long-term hypothyroidism is associated with adrenal insufficiency with abnormalities of hypothalamic–pituitary–adrenal(HPA) axis. Short-term hypothyroidism, on the other hand, is associated with increased pituitary corticotropic cells responsiveness to corticotropin-releasing hormone (CRH) produced by the hypothalamus(29).
5. Hyponatremia
Hypothyroidism is associated to 8% of patients with hyponatremia. Hyponatremia in hypothyroidism is due to a pure renal mechanism, and cannot be ascribed to inappropriate secretion of antidiuretic hormone(30) and severe primary hypothyroidism alone may not be enough to cause hyponatremia in the otherwise healthy individuals(30a).
6. Hashimoto’s Thyroiditis
Hashimoto’s thyroiditis is the most common cause of hypothyroidism as a result of an autoimmune disease.
7. Solitary toxic thyroid nodules
Treatment of patients with solitary toxic thyroid adenomas with 131I (mean dose, 10.3 mCi) showed a possibility in contribution to to late recurrent hyperthyroidism in patients at 4.5, 6, and 10 years after treatment(31).
8. Rhabdomyolysis
Although it is rare, rhabdomyolys, which is damaged skeletal muscle tissue breaks down rapidly, can be associated to hypothyroidism, according to the study by the Selcuk University(32).
9. Thyroid cancer
Thyroid hormone withdrawal may induce acute hypothyroidism in patients with differentiated thyroid cancer and can impair quality of life, according to the study by the University of Athens(33).
10. Restless leg syndrome
Restless leg syndrome may be a result of moderate hypothyroidism(34).
11. Myxedema coma
Myxedema coma, a state of decompensated hypothyroidism, is the extreme process of hypothyroidism, typically seen in patients with severe biochemical hypothyroidism,, according to the study by the Prince Charles Hospital(35).
12. Tarsal Tunnel Syndrome
Tarsal tunnel syndrome, a compression neuropathy and painful foot condition is associated to hypothyroidism, according to the study by the Atkinson Morley’s Hospital, Wimbledon(36).
13. Carpal Tunnel Syndrome
Treatment with radioactive iodine may induce hypothyroidism causes of developed symptoms of bilateral carpal tunnel syndrome(37).
14. Fatty liver
Subclinical hypothyroidism may contribute to the development of non-alcoholic fatty liver disease(38) as a result of impaired liver enzyme levels, according to a cross-sectional study from Korean researchers(38a).
15. Sleep apnea and sleep disorders
Central, obstructive, and mixed patterns of sleep apnea and sleep disorder are commonly observed in hypothyroidism, according to the study by the Medical College of Georgia(39).
E. Misdiagnosis
1. Normal aging process
A diagnosis of hypothyroidism in the elderly can easily be overlooked, easily misdiagnosis due to the signs and symptoms of the disease are common to other diseases typical of old age(40).
2. Reversal deterioration of renal function
Ageing with the deterioration of renal function may delay the diagnosis of hypothyroidism, according to the study by the Military Medical Academy, Clinic of Endocrinology(41).
3. Respiratory failure
Hypothyroid may delay correct diagnosis, due to unexplained respiratory failure in effects of lower than normal thyroid hormone secretion, according to the study by the Servicio de Medicina del Hospital(42).
4. Brain stem infarct
The diagnosis of myxedema coma with longstanding low level of thyroid hormone in the blood was often missed or delayed due to various clinical findings and concomitant medical conditions and precipitating factors, especially for patients with no medical history of hypothyroidism, according to the study by the Hallym University(43).
5. Statin intolerance
Hypothyroidism may be misdiagnosed as statin intolerance, according to the study by Krieger EV, and Knopp RH(44).
6. Hypercholesterolaemia
With no measurement of the concentration of thyroid-stimulating hormone and free hypothyroidism may be misdiagnosed as hypercholesterolaemia, thyroxine(45).
F. Diagnosis
If you are experience certain symptoms of above and/or have had previous thyroid problems or goiter, your doctor may suspect that you have underactive thyroid. Blood test to measure the level of TSH and the level of the thyroid hormone thyroxine and triiodothyronine, depending to the stage of the diseases, are necessary(46).
G. Prevention
G.1. Diet to prevent Hypothyroidism
1. Seaweed, kelp or laver, seafood and seawater fish
Adequate consumption of Seaweed, kelp or laver, seafood and seawater fish may reduce risk for the development of hypothyroidism. According to a study, population inHong Kong, a coastal city in the southern part of China showed a high incidence of transient neonatal hypothyroidism and a relatively high mean cord blood thyrotropin (TSH) concentration(47).
2. Iodized salt
Regular consumption of iodized salt may reduce risk of hypothyroidism and enhance urine iodine concentration in iodine sufficiency areas(48).
3. Seaweed
Intake of seaweed regularly is associated to reduce risk of hypothyroidism through its function in increased I/C concentrations (P < .0001) and serum TSH concentrations(49).
G.2. Antioxidants and phytochemicals to prevent Hypothyroidism
1. Iodine
Iodine, found abundantly in seaweed has been in Japanese diet for many centuries
may induce a protective effect on hypothyroidism and improve prognosis of thyroid autoimmunity (50).
2. Resveratrol
Resveratrol influences thyroid function by enhancing iodide trapping and increasing TSH secretion(51).
3. Polyphenolic flavonoids
Green tea extract at 2.5 g% and 5.0 g% doses and black tea extract only at 5.0 g% dose have the potential to alter the thyroid gland physiology and architecture, through significant decrease in serum T3 and T4, and increase serum thyroid stimulating hormone (TSH)(52).
H. Treatments
H.1. In conventional medicine perspective
Patients with hypothyroidism are treated by thyroid hormone therapy with doses depending to the stage and types of the diseases
1, Levothyroxine
The medication is a prohormone activated by deiodination(a peroxidase enzyme involved in the activation or deactivation of thyroid hormones) in the organs to triiodothyronine(T3 thyroid hormone) for treatment of overt hypothyroidism with low FT4 and elevated TSH or TSH > 10 mU/L, and subclinical hypothyroidism with a TSH between 4 and 10 mU/L and normal FT4, dependjng on the underlying disease and symptoms, according to the study by Medizinische Klinik IV der Universität München(52a).
2. Synthetic thyroxine
In patients with primary hypothyroidism, standard therapy synthetic thyroxine showed effectively in increased triiodothyronine through peripheral conversion(52b).
3. Combination levothyroxine plus liothyronine
Combination levothyroxine plus liothyronine produces same effect as of synthetic thyroxine with no beneficial changes in body weight, serum lipid levels, hypothyroid symptoms, according to University College Dublin(53)(54).
H.2. In Herbal medicine perspective
1. Echinacea
a. Immune modulator
Ethanolic extract of fresh Echinacea purpurea exerts its immune modulator activity in regulation of cell signalling for immune responses against threads, depending to exogenous stimuli, viral infection and exposure to stress(55).
b. Anxiety
Some extracts from Echinacea preparations shoed effectively in decreased anxiety, depending to doses manner(56).
2. Ashwagandha
Ashwagandha, also known as Withania somnifera, a Indian ginseng, used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory and anti-aging, is a nightshape plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean. Ashwagandha enhanced immune function by increasing immunoglobulin production and regulating antibody production through cell signalling, according to the studd(57).
3. Fucus vesiculosus
Fucus vesiculosus, also known as Bladderwrack, has been used extensively to treat goitre, swelling of the thyroid gland related to iodine deficiency and thyroid disorders including underactive thyroid (myxedema), over-sized thyroid gland, according to the study by Unidad de Salud Mental Hospital de Laredois, is a source of iodine, discovered in 1811(57a).
4. Kelp
Kelp, containing high amount of iodine, showed to exert its protective effect on hypothyroidism through improvement of the prognosis of thyroid autoimmunity(50), but excessive intake of iodine-rich seaweed (kelp) may induce hypothyroidism and chronic thyroiditis, according to the study of Japanese study(58).
H.3. In traditional Chinese medicine perspective
1. Yang tonifying herbs
Thyroidectomized rabbits treated by the Yang tonifying herbs showed to increase serum levels of thyroxine (T4) and triiodothyronine (T3), according to the study by the Department of Medicine, University of Western Australia, in a randomly study(59).
2. Baji Zibugao
Baji Zibugao (BJZBG), a medicinal plaster mainly consisting of Radix Morindae Officinalis), showed to maintain the levels of thyroxine (T4), triiodothyronine (T3) on total thyroidectomized rabbits(60).
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
References
(a) http://www.ncbi.nlm.nih.gov/pubmed/17933284
(1) http://www.ncbi.nlm.nih.gov/pubmed/22770939
(1a) http://www.ncbi.nlm.nih.gov/pubmed/14997046
(1b) http://www.ncbi.nlm.nih.gov/pubmed/22989469
(2) http://www.ncbi.nlm.nih.gov/pubmed/22629523
(2a) http://www.ncbi.nlm.nih.gov/pubmed/21675503
(3) http://www.ncbi.nlm.nih.gov/pubmed/17219073
(3a) http://www.ncbi.nlm.nih.gov/pubmed/24693400
(4) http://www.ncbi.nlm.nih.gov/pubmed/21475555
(5) http://www.ncbi.nlm.nih.gov/pubmed/24285104
(6) http://www.ncbi.nlm.nih.gov/pubmed/18285414
(7) http://www.ncbi.nlm.nih.gov/pubmed/19088156
(8) http://www.ncbi.nlm.nih.gov/pubmed/23785061
(8a) http://www.ncbi.nlm.nih.gov/pubmed/23292624
(9) http://www.ncbi.nlm.nih.gov/pubmed/23242401
(10) http://www.ncbi.nlm.nih.gov/pubmed/15684146
(11)http://www.ncbi.nlm.nih.gov/pubmed/18695079
(11a) http://www.ncbi.nlm.nih.gov/pubmed/24910826
(12) http://www.ncbi.nlm.nih.gov/pubmed/11838733
(13) http://www.ncbi.nlm.nih.gov/pubmed/23808881
(13a) http://www.ncbi.nlm.nih.gov/pubmed/8957745
(14) http://www.ncbi.nlm.nih.gov/pubmed/15820614
(15) http://www.ncbi.nlm.nih.gov/pubmed/21656490
(16) http://www.ncbi.nlm.nih.gov/pubmed/20807179
(17) http://www.ncbi.nlm.nih.gov/pubmed/946603
(18) http://www.ncbi.nlm.nih.gov/pubmed/871623
(19) http://www.ncbi.nlm.nih.gov/pubmed/20858880
(20) http://www.ncbi.nlm.nih.gov/pubmed/23565424
(21) http://www.ncbi.nlm.nih.gov/pubmed/16794427
(22) http://www.ncbi.nlm.nih.gov/pubmed/23565424
(23) http://www.ncbi.nlm.nih.gov/pubmed/23777566
(24) http://www.ncbi.nlm.nih.gov/pubmed/23759468
(25) http://www.ncbi.nlm.nih.gov/pubmed/23780375
(25a) http://www.ncbi.nlm.nih.gov/pubmed/23750835
(26) http://www.ncbi.nlm.nih.gov/pubmed/23780374
(27) http://www.ncbi.nlm.nih.gov/pubmed/8323398
(28) http://www.ncbi.nlm.nih.gov/pubmed/23153973
(29) http://www.ncbi.nlm.nih.gov/pubmed/22695985
(30) http://www.ncbi.nlm.nih.gov/pubmed/11246114
(30a) http://www.ncbi.nlm.nih.gov/pubmed/22982798
(30b) http://www.ncbi.nlm.nih.gov/pubmed/24600116
(31) http://www.ncbi.nlm.nih.gov/pubmed/6476634
(32) http://www.ncbi.nlm.nih.gov/pubmed/12803243
(33) http://www.ncbi.nlm.nih.gov/pubmed/17218721
(34) http://www.ncbi.nlm.nih.gov/pubmed/3158897
(35) http://www.ncbi.nlm.nih.gov/pubmed/21058937
(36) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1027394/
(37) http://www.ncbi.nlm.nih.gov/pubmed/7310927
(38) http://www.ncbi.nlm.nih.gov/pubmed/22940010
(38a) http://www.endocrineweb.com/professional/research-updates/thyroid-disorders/connection-between-hypothyroidism-non-alcoholic-fatt
(39) http://www.ncbi.nlm.nih.gov/pubmed/2764018
(40) http://www.ncbi.nlm.nih.gov/pubmed/21640396
(41) http://www.ncbi.nlm.nih.gov/pubmed/22500378
(42) http://www.ncbi.nlm.nih.gov/pubmed/15379058
(43) http://www.ncbi.nlm.nih.gov/pubmed/20808690
(44) http://www.ncbi.nlm.nih.gov/pubmed/19581652
(45) http://www.ncbi.nlm.nih.gov/pubmed/11177166
(46) http://www.ncbi.nlm.nih.gov/pubmed/22443971
(47) http://www.ncbi.nlm.nih.gov/pubmed/8863020
(48) http://www.ncbi.nlm.nih.gov/pubmed/6437632
(49) http://www.ncbi.nlm.nih.gov/pubmed/?term=Seaweed+consumption+increased+I%2FC+concentrations+(P+%3C+.0001)+and+serum+TSH+concentrations
(50) http://www.ncbi.nlm.nih.gov/pubmed/14757962
(51) http://www.ncbi.nlm.nih.gov/pubmed/21946130
(52) http://www.ncbi.nlm.nih.gov/pubmed/20801949
(52a) http://www.ncbi.nlm.nih.gov/pubmed/23801264
(52b) http://www.ncbi.nlm.nih.gov/pubmed/23900472
(55) http://www.ncbi.nlm.nih.gov/pubmed/21726792
(56) http://www.ncbi.nlm.nih.gov/pubmed/21031616
(57) http://www.ncbi.nlm.nih.gov/pubmed/21619924
(57a) http://www.ncbi.nlm.nih.gov/pubmed/22127913
(58) http://www.ncbi.nlm.nih.gov/pubmed/8106628
(59) http://www.ncbi.nlm.nih.gov/pubmed/9533431
(60) http://www.ncbi.nlm.nih.gov/pubmed/7744389
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Thyroid disease
Thyroid disease is defined as a condition of malfunction of thyroid gland
Thyroid disease: Hypothyroidism
Hypothyroidism is a condition in which the thyroid gland is under active produced very little thyroid hormones.
A. Symptoms
Symptoms of the Hypothyroidism is depended to the severe stage of the disease, due to its progression slowly over years. Most common symptoms include
1. Weight gain and fatigue
Hyperthyroidism is associated to weight gain, especially in patients with co-existence of diabetes(1).
The comparable study of patients with thyroid carcinoma (DTC) and 138 with autoimmune hypothyroidism (AIH), also indicated a significantly higher levels of fatigue in hypothyroidism patients(1b). Statistics of study of 198 consecutive breast cancer patients receiving adjuvant chemotherapy, 22.2% of this patient population showed a significant and progressive weight gain of 6.7 lbs, and 94% of all patients with reported fatigue caused cytotoxic agents influence hypothyroidism in breast cancer patients(1a).
2. Vitiligo and alopecia areata
Vitiligo is associated with autoimmune endocrine disorders, especially with hypothyroidism(2). Primary hypothyroidism patients is at increased risk to develop vitiligo, depigmentation of parts of the skin and hair lost from some or all areas of the body, especially in the scalp(2a)
3. Chronic constipation(3a)
Hypothyroidism may induce the pathogenesis of constipation, according to the study by the University of California at Los Angele(3).
4. Urticaria and puffiness of hands and feet, yellow ivory skin, coarse rough dry skin
Hypothyroid women showed a significantly higher frequency of urticaria and puffiness of hands and feet, yellow ivory skin, coarse rough dry skin(4).
5. Depression
Patients with hypothyroidism have a higher occurrence of depressive syndrome, caused by alterations in blood flow and glucose metabolism in the brain(5).
6. Mood and motor learning
Oral administration of usual dose l-T(4) (euthyroid arm) vs. higher dose l-T(4) (subclinical thyrotoxicosis arm) , showed to improve confusion, mood and motor learning in patients with hypothyroidism(6).
B. Risk Factors and Causes
B.1. Risk factors
1. Family history
The risk of progression to overt hypothyroidism is related to number of factors including, family history(11a). Family members of patients with autoimmune thyroid disorder(AITD) are at increased risk for AITD, but not all will develop overt hypothyroidism or hyperthyroidism, according to the study by the Academic Medical Center, Netherlands(11).
2. Smoking
Smoking is a powerful risk factor for thyroid disease, especially in populations with a high smoking frequency, according to the study by the Aarhus University Hospital(12). Smoking reduced the risk of hypothyroidism but increased the risk of hypothyroidism in patients with Hashimoto's thyroiditis(13)(13a).
3. Age
Hypothyroidism is associated to increased age. In the old rat, the pituitary thyrotrophs increase hormonal secretion in response to decreased levels of thyroid hormones due to aging, even when the thyroid hormone levels are dramatically reduced, according to study of Dutch-Miranda and Wistar rats(14).
4. Autoimmune disorders, thyroid injury, post partum state, are common signs of patients with hypothyroidism, according to Dr. Zulewski H. at Universitätsspital Basel(15).
5. Radiation
Light microscopy, electron microscopy and immunohistochemical methods, can cause pathological changes in the thyroid gland throuigh altering the gland structure and enhancing apoptosis(16).
6. Post pregnancy
Women with autoimmune thyroiditis are associated to increase risk of hypothyroidism at 3-6 months post-partum(17).
7. Partial thyroidectomy
Partial thyroidectomy, a removal of part of thyroid gland induces overall prevalence of 16% of hypothyroidism(18).
B.2. Causes
1. Autoimmune response
Autoimmune disease is an over reaction of immune response of the body against substances and tissues normally presented in the body. Primary overt autoimmune hypothyroidism is divided into primary idiopathic hypothyroidism with thyroid atrophy (Ord’s disease) and hypothyroidism with goitre (Hashimoto’s disease)(7).
2. Congenital Hypothyroidism(CH)
Baby with postdate delivery and macrosomia are associated to increased risk od congenital hypothyroidism(8a).The incidence of CH was greater in our population for 2007 to 2010, after an unexplained decline, according to the study by the Columbia University Medical Center(8).
3. Pituitary disorder
Pituitary disorders, is associated to reduce or increase secretion of hormones, affected growth and the functions of other glands in the body. A normal TSH does not exclude central hypothyroidism, but pituitary disease, with potential for deficiency of other anterior pituitary hormones, may contribute to correctly diagnosed hypothyroidism(9).
4. Pregnancy
Women with TSH values at or above the 97.5th percentile for gestational age with free thyroxine more than 0.680 ng/dL at the time screening and were retrospectively identified with subclinical hypothyroidism, according to University of Texas Southwestern Medical Center(10).
2. Iodine deficiency
Iodine is a key element in the synthesis of thyroid hormones, severe iodine deficiency is associated to risks of hypothyroidism, goiter, and cretinism due to biochemical alterations, according to Verheesen RH and Schweitzer CM(11).
C. Complications
1. Coronary heart disease and mortality
Subclinical hypothyroidism is associated with an increased risk of the development of coronary heart disease (CHD). CHD mortality is higher in patients with diagnosed elevated TSH levels, particularly in those TSH concentration of 10 mIU/L or greater(19).
2. Pre-eclampsia, perinatal mortality, and miscarriage
Thyroid dysfunction interferes with women reproductive physiology, reduces the likelihood of pregnancy and adversely affects pregnancy outcome. According to the study by the MGM Medical College, pregnant women with subclinical hypothyroidism has an increased risk of complications, especially pre-eclampsia, perinatal mortality, and miscarriage(21).
3. Ovulatory dysfunction, pregnancy loss
Subclinical hypothyroidism may be associated with ovulatory dysfunction and adverse pregnancy outcome(22).
4. Increased susceptibility to inflammatory diseases
Hypothyroidism during gestation can influence the outcome of a CNS inflammatory disease, such as EAE, according to the study by the Universidad Andres Bello, Ciencias Biologicas(23).
5. Auditory function
Iodine deficiency may contribute auditory function (deaf and hard of hearing) in process information. Hearing deficit, an invisible abnormality, has major consequences for educational and social skills if not detected, according to the study by the Wageningen University, Wageningen(24).
6. Hearing loss
Hearing loss contribute a significant problem, in adult patients with severe chronic hypothyroidism(25).
D. Diseases associated to hypothyroidism
1. Systemic Sclerosis
Systemic sclerosis (SSc) is a connective tissue disease of unknown etiology, and several studies reported its association with thyroid autoimmune disorders, including hypothyroidism and thyroid dysfunction(26).
2. Osteoarthritis and fibromyalgia
Thyroid dysfunction is seen at least three times more often in women with RA than in women with similar demographic features with non-inflammatory rheumatic diseases such as osteoarthritis and fibromyalgia(27).
3. Type 1 diabetes mellitus (T1DM)
8% of patients with T1DM had hypothyroidism, according to the data presented to department of Endocrinology from May 1997 to December 2011(28).
4. Adrenal insufficiency
According to study, long-term hypothyroidism is associated with adrenal insufficiency with abnormalities of hypothalamic–pituitary–adrenal(HPA) axis. Short-term hypothyroidism, on the other hand, is associated with increased pituitary corticotropic cells responsiveness to corticotropin-releasing hormone (CRH) produced by the hypothalamus(29).
5. Hyponatremia
Hypothyroidism is associated to 8% of patients with hyponatremia. Hyponatremia in hypothyroidism is due to a pure renal mechanism, and cannot be ascribed to inappropriate secretion of antidiuretic hormone(30) and severe primary hypothyroidism alone may not be enough to cause hyponatremia in the otherwise healthy individuals(30a).
6. Hashimoto’s Thyroiditis
Hashimoto’s thyroiditis is the most common cause of hypothyroidism as a result of an autoimmune disease.
7. Solitary toxic thyroid nodules
Treatment of patients with solitary toxic thyroid adenomas with 131I (mean dose, 10.3 mCi) showed a possibility in contribution to to late recurrent hyperthyroidism in patients at 4.5, 6, and 10 years after treatment(31).
8. Rhabdomyolysis
Although it is rare, rhabdomyolys, which is damaged skeletal muscle tissue breaks down rapidly, can be associated to hypothyroidism, according to the study by the Selcuk University(32).
9. Thyroid cancer
Thyroid hormone withdrawal may induce acute hypothyroidism in patients with differentiated thyroid cancer and can impair quality of life, according to the study by the University of Athens(33).
10. Restless leg syndrome
Restless leg syndrome may be a result of moderate hypothyroidism(34).
11. Myxedema coma
Myxedema coma, a state of decompensated hypothyroidism, is the extreme process of hypothyroidism, typically seen in patients with severe biochemical hypothyroidism,, according to the study by the Prince Charles Hospital(35).
12. Tarsal Tunnel Syndrome
Tarsal tunnel syndrome, a compression neuropathy and painful foot condition is associated to hypothyroidism, according to the study by the Atkinson Morley’s Hospital, Wimbledon(36).
13. Carpal Tunnel Syndrome
Treatment with radioactive iodine may induce hypothyroidism causes of developed symptoms of bilateral carpal tunnel syndrome(37).
14. Fatty liver
Subclinical hypothyroidism may contribute to the development of non-alcoholic fatty liver disease(38) as a result of impaired liver enzyme levels, according to a cross-sectional study from Korean researchers(38a).
15. Sleep apnea and sleep disorders
Central, obstructive, and mixed patterns of sleep apnea and sleep disorder are commonly observed in hypothyroidism, according to the study by the Medical College of Georgia(39).
E. Misdiagnosis
1. Normal aging process
A diagnosis of hypothyroidism in the elderly can easily be overlooked, easily misdiagnosis due to the signs and symptoms of the disease are common to other diseases typical of old age(40).
2. Reversal deterioration of renal function
Ageing with the deterioration of renal function may delay the diagnosis of hypothyroidism, according to the study by the Military Medical Academy, Clinic of Endocrinology(41).
3. Respiratory failure
Hypothyroid may delay correct diagnosis, due to unexplained respiratory failure in effects of lower than normal thyroid hormone secretion, according to the study by the Servicio de Medicina del Hospital(42).
4. Brain stem infarct
The diagnosis of myxedema coma with longstanding low level of thyroid hormone in the blood was often missed or delayed due to various clinical findings and concomitant medical conditions and precipitating factors, especially for patients with no medical history of hypothyroidism, according to the study by the Hallym University(43).
5. Statin intolerance
Hypothyroidism may be misdiagnosed as statin intolerance, according to the study by Krieger EV, and Knopp RH(44).
6. Hypercholesterolaemia
With no measurement of the concentration of thyroid-stimulating hormone and free hypothyroidism may be misdiagnosed as hypercholesterolaemia, thyroxine(45).
F. Diagnosis
If you are experience certain symptoms of above and/or have had previous thyroid problems or goiter, your doctor may suspect that you have underactive thyroid. Blood test to measure the level of TSH and the level of the thyroid hormone thyroxine and triiodothyronine, depending to the stage of the diseases, are necessary(46).
G. Prevention
G.1. Diet to prevent Hypothyroidism
1. Seaweed, kelp or laver, seafood and seawater fish
Adequate consumption of Seaweed, kelp or laver, seafood and seawater fish may reduce risk for the development of hypothyroidism. According to a study, population inHong Kong, a coastal city in the southern part of China showed a high incidence of transient neonatal hypothyroidism and a relatively high mean cord blood thyrotropin (TSH) concentration(47).
2. Iodized salt
Regular consumption of iodized salt may reduce risk of hypothyroidism and enhance urine iodine concentration in iodine sufficiency areas(48).
3. Seaweed
Intake of seaweed regularly is associated to reduce risk of hypothyroidism through its function in increased I/C concentrations (P < .0001) and serum TSH concentrations(49).
G.2. Antioxidants and phytochemicals to prevent Hypothyroidism
1. Iodine
Iodine, found abundantly in seaweed has been in Japanese diet for many centuries
may induce a protective effect on hypothyroidism and improve prognosis of thyroid autoimmunity (50).
2. Resveratrol
Resveratrol influences thyroid function by enhancing iodide trapping and increasing TSH secretion(51).
3. Polyphenolic flavonoids
Green tea extract at 2.5 g% and 5.0 g% doses and black tea extract only at 5.0 g% dose have the potential to alter the thyroid gland physiology and architecture, through significant decrease in serum T3 and T4, and increase serum thyroid stimulating hormone (TSH)(52).
H. Treatments
H.1. In conventional medicine perspective
Patients with hypothyroidism are treated by thyroid hormone therapy with doses depending to the stage and types of the diseases
1, Levothyroxine
The medication is a prohormone activated by deiodination(a peroxidase enzyme involved in the activation or deactivation of thyroid hormones) in the organs to triiodothyronine(T3 thyroid hormone) for treatment of overt hypothyroidism with low FT4 and elevated TSH or TSH > 10 mU/L, and subclinical hypothyroidism with a TSH between 4 and 10 mU/L and normal FT4, dependjng on the underlying disease and symptoms, according to the study by Medizinische Klinik IV der Universität München(52a).
2. Synthetic thyroxine
In patients with primary hypothyroidism, standard therapy synthetic thyroxine showed effectively in increased triiodothyronine through peripheral conversion(52b).
3. Combination levothyroxine plus liothyronine
Combination levothyroxine plus liothyronine produces same effect as of synthetic thyroxine with no beneficial changes in body weight, serum lipid levels, hypothyroid symptoms, according to University College Dublin(53)(54).
H.2. In Herbal medicine perspective
1. Echinacea
a. Immune modulator
Ethanolic extract of fresh Echinacea purpurea exerts its immune modulator activity in regulation of cell signalling for immune responses against threads, depending to exogenous stimuli, viral infection and exposure to stress(55).
b. Anxiety
Some extracts from Echinacea preparations shoed effectively in decreased anxiety, depending to doses manner(56).
2. Ashwagandha
Ashwagandha, also known as Withania somnifera, a Indian ginseng, used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory and anti-aging, is a nightshape plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean. Ashwagandha enhanced immune function by increasing immunoglobulin production and regulating antibody production through cell signalling, according to the studd(57).
3. Fucus vesiculosus
Fucus vesiculosus, also known as Bladderwrack, has been used extensively to treat goitre, swelling of the thyroid gland related to iodine deficiency and thyroid disorders including underactive thyroid (myxedema), over-sized thyroid gland, according to the study by Unidad de Salud Mental Hospital de Laredois, is a source of iodine, discovered in 1811(57a).
4. Kelp
Kelp, containing high amount of iodine, showed to exert its protective effect on hypothyroidism through improvement of the prognosis of thyroid autoimmunity(50), but excessive intake of iodine-rich seaweed (kelp) may induce hypothyroidism and chronic thyroiditis, according to the study of Japanese study(58).
H.3. In traditional Chinese medicine perspective
1. Yang tonifying herbs
Thyroidectomized rabbits treated by the Yang tonifying herbs showed to increase serum levels of thyroxine (T4) and triiodothyronine (T3), according to the study by the Department of Medicine, University of Western Australia, in a randomly study(59).
2. Baji Zibugao
Baji Zibugao (BJZBG), a medicinal plaster mainly consisting of Radix Morindae Officinalis), showed to maintain the levels of thyroxine (T4), triiodothyronine (T3) on total thyroidectomized rabbits(60).
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References
(a) http://www.ncbi.nlm.nih.gov/pubmed/17933284
(1) http://www.ncbi.nlm.nih.gov/pubmed/22770939
(1a) http://www.ncbi.nlm.nih.gov/pubmed/14997046
(1b) http://www.ncbi.nlm.nih.gov/pubmed/22989469
(2) http://www.ncbi.nlm.nih.gov/pubmed/22629523
(2a) http://www.ncbi.nlm.nih.gov/pubmed/21675503
(3) http://www.ncbi.nlm.nih.gov/pubmed/17219073
(3a) http://www.ncbi.nlm.nih.gov/pubmed/24693400
(4) http://www.ncbi.nlm.nih.gov/pubmed/21475555
(5) http://www.ncbi.nlm.nih.gov/pubmed/24285104
(6) http://www.ncbi.nlm.nih.gov/pubmed/18285414
(7) http://www.ncbi.nlm.nih.gov/pubmed/19088156
(8) http://www.ncbi.nlm.nih.gov/pubmed/23785061
(8a) http://www.ncbi.nlm.nih.gov/pubmed/23292624
(9) http://www.ncbi.nlm.nih.gov/pubmed/23242401
(10) http://www.ncbi.nlm.nih.gov/pubmed/15684146
(11)http://www.ncbi.nlm.nih.gov/pubmed/18695079
(11a) http://www.ncbi.nlm.nih.gov/pubmed/24910826
(12) http://www.ncbi.nlm.nih.gov/pubmed/11838733
(13) http://www.ncbi.nlm.nih.gov/pubmed/23808881
(13a) http://www.ncbi.nlm.nih.gov/pubmed/8957745
(14) http://www.ncbi.nlm.nih.gov/pubmed/15820614
(15) http://www.ncbi.nlm.nih.gov/pubmed/21656490
(16) http://www.ncbi.nlm.nih.gov/pubmed/20807179
(17) http://www.ncbi.nlm.nih.gov/pubmed/946603
(18) http://www.ncbi.nlm.nih.gov/pubmed/871623
(19) http://www.ncbi.nlm.nih.gov/pubmed/20858880
(20) http://www.ncbi.nlm.nih.gov/pubmed/23565424
(21) http://www.ncbi.nlm.nih.gov/pubmed/16794427
(22) http://www.ncbi.nlm.nih.gov/pubmed/23565424
(23) http://www.ncbi.nlm.nih.gov/pubmed/23777566
(24) http://www.ncbi.nlm.nih.gov/pubmed/23759468
(25) http://www.ncbi.nlm.nih.gov/pubmed/23780375
(25a) http://www.ncbi.nlm.nih.gov/pubmed/23750835
(26) http://www.ncbi.nlm.nih.gov/pubmed/23780374
(27) http://www.ncbi.nlm.nih.gov/pubmed/8323398
(28) http://www.ncbi.nlm.nih.gov/pubmed/23153973
(29) http://www.ncbi.nlm.nih.gov/pubmed/22695985
(30) http://www.ncbi.nlm.nih.gov/pubmed/11246114
(30a) http://www.ncbi.nlm.nih.gov/pubmed/22982798
(30b) http://www.ncbi.nlm.nih.gov/pubmed/24600116
(31) http://www.ncbi.nlm.nih.gov/pubmed/6476634
(32) http://www.ncbi.nlm.nih.gov/pubmed/12803243
(33) http://www.ncbi.nlm.nih.gov/pubmed/17218721
(34) http://www.ncbi.nlm.nih.gov/pubmed/3158897
(35) http://www.ncbi.nlm.nih.gov/pubmed/21058937
(36) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1027394/
(37) http://www.ncbi.nlm.nih.gov/pubmed/7310927
(38) http://www.ncbi.nlm.nih.gov/pubmed/22940010
(38a) http://www.endocrineweb.com/professional/research-updates/thyroid-disorders/connection-between-hypothyroidism-non-alcoholic-fatt
(39) http://www.ncbi.nlm.nih.gov/pubmed/2764018
(40) http://www.ncbi.nlm.nih.gov/pubmed/21640396
(41) http://www.ncbi.nlm.nih.gov/pubmed/22500378
(42) http://www.ncbi.nlm.nih.gov/pubmed/15379058
(43) http://www.ncbi.nlm.nih.gov/pubmed/20808690
(44) http://www.ncbi.nlm.nih.gov/pubmed/19581652
(45) http://www.ncbi.nlm.nih.gov/pubmed/11177166
(46) http://www.ncbi.nlm.nih.gov/pubmed/22443971
(47) http://www.ncbi.nlm.nih.gov/pubmed/8863020
(48) http://www.ncbi.nlm.nih.gov/pubmed/6437632
(49) http://www.ncbi.nlm.nih.gov/pubmed/?term=Seaweed+consumption+increased+I%2FC+concentrations+(P+%3C+.0001)+and+serum+TSH+concentrations
(50) http://www.ncbi.nlm.nih.gov/pubmed/14757962
(51) http://www.ncbi.nlm.nih.gov/pubmed/21946130
(52) http://www.ncbi.nlm.nih.gov/pubmed/20801949
(52a) http://www.ncbi.nlm.nih.gov/pubmed/23801264
(52b) http://www.ncbi.nlm.nih.gov/pubmed/23900472
(55) http://www.ncbi.nlm.nih.gov/pubmed/21726792
(56) http://www.ncbi.nlm.nih.gov/pubmed/21031616
(57) http://www.ncbi.nlm.nih.gov/pubmed/21619924
(57a) http://www.ncbi.nlm.nih.gov/pubmed/22127913
(58) http://www.ncbi.nlm.nih.gov/pubmed/8106628
(59) http://www.ncbi.nlm.nih.gov/pubmed/9533431
(60) http://www.ncbi.nlm.nih.gov/pubmed/7744389
Endometriosis: The Effects of Green Pepper(Revised edition with references)
By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
During the last stage of the menstrual cycle, normally a layer of endometriosis lining on the inside of the uterus is expelled, known as menstruation blood, instead some of the endometriosis tissues grow somewhere in the body to cause endometriosis. Endometriosis also react to hormone signals of the monthly menstrual cycle, by building and breaking up tissues and eliminating them through menstrual period.
Green Pepper, cultivated all over the world in suitable climate as vegetable for commercial profits, is a genus Capsicum, belonging to the family Solanaceae, native to southern North America and northern South America.
1. Bioflavonoids
Bioflavonoids in the green pepper beside helping to improve the function of vitamin C(1), it's quercetin is the vital substance that helps to reduce inflammation(2) resulting in reducing the risk of forming of endometrial implants and adhesion(3).
2. Immune system
Green pepper also helps to increase lymphocytes production that plays an important and integral role in the body's defenses from both tumor(4), virally infected cells and endometrial implants and adhesion(4).
3. Digestive system
The mild spicy vegetable also plays an important role in digestive absorption(5) of vital vitamins and minerals, thereby increasing the normal body function in reducing the tension of nervous system(6)(7) during menstrual cycle.
4. Vitamin C
Beside helping to strengthen the small veins in the abdomen(8), it also increase the production of blood platelets(10) that helps to reduce menstrual bleeding(9).
5. Circulation System
Green pepper is said to enhance the blood circulation by inhibiting bad cholesterol(11) and strengthening the arterial wall(11), thereby helping to increase blood flow(9) to the abdominal region resulting in lessening the period pain(12) caused by blood stagnation.
6. Potassium
Potassium in green pepper besides helping our body in transmission of electrochemical impulses(16), it also is vital for maintaining the proper ratio with sodium in the body tissues(13). Without controlling the levels of sodium(14), it causes fluid retention(14) in the body tissues and hypertension(15).
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Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
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References
(1) [Effect of bioflavonoids on the utilization of the vitamin C activity of crystalline L-dehydroascorbic acid].[Article in German] by Zloch Z.(PubMed)
(2) In vivo quercitrin anti-inflammatory effect involves release of quercetin, which inhibits inflammation through down-regulation of the NF-kappaB pathway by Comalada M1, Camuesco D, Sierra S, Ballester I, Xaus J, Gálvez J, Zarzuelo A.(PubMed)
(3) [Perspectives on endometriosis: new physiopathologic approaches and treatments].[Article in French] by Vigano P1; D'après la communication de.(PubMed)
(4) Luteolin inhibits hyperglycemia-induced proinflammatory cytokine production and its epigenetic mechanism in human monocytes by Kim HJ1, Lee W, Yun JM.(PubMed)
(5) Dietary agonists of TRPV1 inhibit gastric acid secretion in mice by Okumi H1, Tashima K, Matsumoto K, Namiki T, Terasawa K, Horie S.(PubMed)
(6) Effects of nutrients (in food) on the structure and function of the nervous system: update on dietary requirements for brain. Part 1: micronutrients by Bourre JM.(PubMed)
(7) [The role of nutritional factors on the structure and function of the brain: an update on dietary requirements].[Article in French] by Bourre JM.(PubMed)
(8) Effects of benfluorex-vitamin C supplementation on cutaneous capillaries of diabetic rats by Sari Kiliçaslan SM1, Ozer C.(PubMed)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
During the last stage of the menstrual cycle, normally a layer of endometriosis lining on the inside of the uterus is expelled, known as menstruation blood, instead some of the endometriosis tissues grow somewhere in the body to cause endometriosis. Endometriosis also react to hormone signals of the monthly menstrual cycle, by building and breaking up tissues and eliminating them through menstrual period.
Green Pepper, cultivated all over the world in suitable climate as vegetable for commercial profits, is a genus Capsicum, belonging to the family Solanaceae, native to southern North America and northern South America.
1. Bioflavonoids
Bioflavonoids in the green pepper beside helping to improve the function of vitamin C(1), it's quercetin is the vital substance that helps to reduce inflammation(2) resulting in reducing the risk of forming of endometrial implants and adhesion(3).
2. Immune system
Green pepper also helps to increase lymphocytes production that plays an important and integral role in the body's defenses from both tumor(4), virally infected cells and endometrial implants and adhesion(4).
3. Digestive system
The mild spicy vegetable also plays an important role in digestive absorption(5) of vital vitamins and minerals, thereby increasing the normal body function in reducing the tension of nervous system(6)(7) during menstrual cycle.
4. Vitamin C
Beside helping to strengthen the small veins in the abdomen(8), it also increase the production of blood platelets(10) that helps to reduce menstrual bleeding(9).
5. Circulation System
Green pepper is said to enhance the blood circulation by inhibiting bad cholesterol(11) and strengthening the arterial wall(11), thereby helping to increase blood flow(9) to the abdominal region resulting in lessening the period pain(12) caused by blood stagnation.
6. Potassium
Potassium in green pepper besides helping our body in transmission of electrochemical impulses(16), it also is vital for maintaining the proper ratio with sodium in the body tissues(13). Without controlling the levels of sodium(14), it causes fluid retention(14) in the body tissues and hypertension(15).
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
References
(1) [Effect of bioflavonoids on the utilization of the vitamin C activity of crystalline L-dehydroascorbic acid].[Article in German] by Zloch Z.(PubMed)
(2) In vivo quercitrin anti-inflammatory effect involves release of quercetin, which inhibits inflammation through down-regulation of the NF-kappaB pathway by Comalada M1, Camuesco D, Sierra S, Ballester I, Xaus J, Gálvez J, Zarzuelo A.(PubMed)
(3) [Perspectives on endometriosis: new physiopathologic approaches and treatments].[Article in French] by Vigano P1; D'après la communication de.(PubMed)
(4) Luteolin inhibits hyperglycemia-induced proinflammatory cytokine production and its epigenetic mechanism in human monocytes by Kim HJ1, Lee W, Yun JM.(PubMed)
(5) Dietary agonists of TRPV1 inhibit gastric acid secretion in mice by Okumi H1, Tashima K, Matsumoto K, Namiki T, Terasawa K, Horie S.(PubMed)
(6) Effects of nutrients (in food) on the structure and function of the nervous system: update on dietary requirements for brain. Part 1: micronutrients by Bourre JM.(PubMed)
(7) [The role of nutritional factors on the structure and function of the brain: an update on dietary requirements].[Article in French] by Bourre JM.(PubMed)
(8) Effects of benfluorex-vitamin C supplementation on cutaneous capillaries of diabetic rats by Sari Kiliçaslan SM1, Ozer C.(PubMed)
(9) Tetrahydrobiopterin, L-arginine and vitamin C act synergistically to decrease oxidant stress and increase nitric oxide that increases blood flow recovery after hindlimb ischemia in the rat by Yan J1, Tie G, Messina LM.(PubMed)
(11) Red pepper attenuates cholesteryl ester transfer protein activity and atherosclerosis in cholesterol-fed rabbits by Kwon MJ1, Song YS, Choi MS, Song YO.(PubMed)
(12) The two faces of capsaicin by Bode AM1, Dong Z.(PubMed)
(13) Are large amounts of sodium stored in an osmotically inactive form during sodium retention? Balance studies in freely moving dogs by Seeliger E1, Ladwig M, Reinhardt HW.(PubMed)
(14) Some sodium, potassium and water changes in the elderly and their treatment by Andreucci VE1, Russo D, Cianciaruso B, Andreucci M.(PubMed)
(15) A risk-benefit assessment of losartan potassium in the treatment of hypertension by Burrell LM.(PubMed)
(14) Some sodium, potassium and water changes in the elderly and their treatment by Andreucci VE1, Russo D, Cianciaruso B, Andreucci M.(PubMed)
(15) A risk-benefit assessment of losartan potassium in the treatment of hypertension by Burrell LM.(PubMed)
(16) Electrochemical Impulse
#Healthy #recipe for Busy #Mom: Asian #Beef Rolls
Posted By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Recipe contributed by Everything Busy Moms' Cook Book By Susan Whetzel Published by Adamsmedia. You can view its website at www.everything.com.
The cold entrée wraps tender roast beef around crunchy coleslaw mix seasoned with Asian ingredients. Yum!
Serves 4
Ingredients
3 tablespoon hoisin sauce
1/4 cup plum sauce
11/2 cups coleslaw mix
1/4 chopped green onion
6 sliced cooked deli roast beef
1. In medium bowl, combine hoisin sauce and plum sauce and mix well. Stir in coleslaw mix and green onion and mix gently.
2. Place roast beef slices on work surface and divide coleslaw mixture among them. Roll up beef slices. enclosing filling. Serve immediately, or cover and refrigerate up to 8 hours before serving.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to Healthy Foods Index http://kylejnorton.blogspot.ca/p/healthy-foods-index.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Recipe contributed by Everything Busy Moms' Cook Book By Susan Whetzel Published by Adamsmedia. You can view its website at www.everything.com.
The cold entrée wraps tender roast beef around crunchy coleslaw mix seasoned with Asian ingredients. Yum!
Serves 4
Ingredients
3 tablespoon hoisin sauce
1/4 cup plum sauce
11/2 cups coleslaw mix
1/4 chopped green onion
6 sliced cooked deli roast beef
1. In medium bowl, combine hoisin sauce and plum sauce and mix well. Stir in coleslaw mix and green onion and mix gently.
2. Place roast beef slices on work surface and divide coleslaw mixture among them. Roll up beef slices. enclosing filling. Serve immediately, or cover and refrigerate up to 8 hours before serving.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
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Tuesday 18 November 2014
(Preview) Most common diseases of 50 plus - Thyroid Disease - Thyroid cancer : Preventions, Managements and Treatments
By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Thyroid disease
Thyroid disease is defined as a condition of malfunction of thyroid.
Types of thyroid cancer
The most common types of thyroid cancer include
1. Papillary thyroid cancer
Papillary thyroid cancer, the most common type of thyroid cancer with high proclivity for recurrence or persistence found in patients with BRAF(a protein, involved in directing cell growth) mutation(1), makes up about 80 percent of all thyroid cancers. The cancer tends to develop in the women age group between 30-40 and grows slowly. Papillary thyroid cancer can be cured if diagnosed early.
2. Follicular thyroid cancer
Follicular thyroid cancer, a slowly grew cancer with peak onset between ages 40 to 60, and second most common thyroid cancer, makes up about 15 percent of all cases with mostly in women over 50 years of age(2). Follicular thyroid cancer can be treated successful, if diagnosed early, depending to site of metastasis, histology, and iodine avidity of the metastasis(3).
3. Medullary thyroid cancer
Medullary thyroid cancer, third most common thyroid cancer made up about 5 percent of all cases(4), arises from thyroid hormone producing cells with abnormally high levels of calcitonin(6). Medullary thyroid cancer tends to grow slowly but can spread to distant parts of the body, if not treated early, depending to interdisciplinary communication, and patient education and encouragement of enhance compliance and safety, etc.(5).
4. Anaplastic thyroid cancer
Anaplastic thyroid cancer the rare case of thyroid cancer, makes up less than 2 percent of all cases(7). The cancer cells tend to grow and spread very quickly responsible for the majority of death from all thyroid cancers and have a median survival of 6 months(7). Anaplastic thyroid cancer is deadly, with only 10% of survival rate, and median survival of 3 to 5 months(8) after it is diagnosed.
A. Symptoms
1. Lump in the neck(9)(10)(11)
Due to uncontrollable cells growth and only 5% of this lumps are found to be cancerous.
2. Enlarged lymph node(12)(14)
Cancer has invaded the lymph nodes and its surrounding
3. Change of voice(13)
Hoarseness or difficulty speaking in a normal voice as the tumor has affected the voice-box region.
4. Pain or discomfort in the throat or neck(15)(16).
5. Problem of swallowing(17)
As a result of tumor has affected the esophagus or of enlarged lymph node
6. Difficult breathing(18)
Cancer may have invaded the lung or may affect either the upper or lower of respiratory track or due to enlarged lymph node
7. Other local compressive symptoms, such as dysphagia, dysphonia, stridor, neck tenderness and dyspnea(19)
B. Causes and risk factors
1. Age
Risk of thyroid cancer increases with age(20).
2. Gender
Women are twice at risk to develop thyroid cancer than men(20).
3. Race
In US, according to statistic, Caucasians are at greater risk than African Americans to develop thyroid cancer(21). Women in ethnic Asian/Pacific Islander and Hispanic origin are associated to higher risk of thyroid cancer(21).
5. Exposure to radiation(22)(23)
People who exposed to the radiation therapy at a young age for treatment of certain cancer are at higher risk to develop thyroid cancer at later age(24).
6. Family history(25)
Increased risk of thyroid cancer if your direct family has a history of thyroid cancer(26).
7. Chronic goiter(27)
Risk of thyroid cancer increased if you have a history of enlargement of the thyroid gland.
8. Exposure to certain chemical agents(28)(29)
In a study by Copenhagen researchers, the effect of chemicals such as polychlorinated biphenyls and dioxins on the thyroid. is associated with the of correlation between chemicals and increased TSH cause of an increased opportunity for mutations and the development of cancer.
9. Low level of iodine
People with life-long iodine deficiency are more likely to develop thyroid cancer(30)(31).
10. Heredity
People born with mutation in the RET proto-oncogene are at risk in developing medullary thyroid cancer (MTC)(32)(33).
11. Etc.
C. Diagnosis and tests
After family history and careful physical examination, If you have a family history of medullary thyroid cancer, blood test for calcitoninis is necessary
1. Blood test
The blood is to determine the levels of calcitoninis. Elevation of calcitoninis may be a sign of thyroid cancer(34).
2. Thyroid scan(35)
With the inject of asotope, your doctor can view the images capture and classify them, according the amount asotope of absorption by the thyroid gland. If the gland is actively taking up the isotope, ultrasound will show whether the abnormality is a cyst or not. Thyroid biopsy may be required to further assessment.
3. Thyroid biopsy(36)
In thyroid biopsy, a sample of the effected area is taken by a thin needle instrument (thin needle aspirate) under local anesthesia and examined by a pathologist under microscopy to view the type and stage of the cancer.
4. CT Scan (computerized tomography)(37)(38)
A CT scan generates is a large series of two-dimensional X-ray images taken around a single axis of rotation, to create a three-dimensional picture of the inside of the body in details.The pictures are viewed by your doctor to see the extent of the tumors abnormalities, such as spreading of cancer to the nearby structure and lymph nodes.
5. Etc.
D. Grades
The Grades of Thyroid cancer are depending to the tendency of spreading. Low grade cancers(39) in most cases, usually grow more slowly and are less likely to spread while high grade cancer indicates otherwise(40)(41).
E. Stages(42)
Thyroid cancer is classified as 5 stages
1. Stage 0
If the cancerous cell have not penetrated in deeper tissue but in the surface of the thyroid lining.
a.1. Stage IA1:
The spreading is not less than 3mm(1/8 inch) deep and & less than 7mm (1/4 inch) wide.
a.2. Stage IA2: The invasion area is ≥ 3 mm but ≤ 5 mm (about 1/5 inch) deep and & less than 7 mm (about 1/4 inch) wide.
b. Stage IB:
The cancer in this stage have invaded the connective tissue, & less than 5mm (1/5 inch).
b.1. Stage IB1:
Cancer is 4 cm large (1 3/4 inches).
b.2. Stage IB2:
Cancer is ≥ 4 cm (1 3/4 inches) but & less than 5cm (1/5 inch)
3. Stage II
In stage II, the cancerous cells have spread to distant tissues, but is still within the thyroid gland.
4. Stage III
In this stage, cancerous cells has spread to the tissues immediately surrounding the thyroid gland
5. Stage IV
In this stage, cancerous cells has spread to the tissues immediately outside of the thyroid gland, other distant parts of the body.
G. Prevention
G.1. What to avoid
1. Potassium Iodide
Potassium Iodide (KI) is one of the drug used to absorb radioactive iodine cause of thyroid disease and cancer. Today it has been used worldwide to prevent thyroid cancer in people who are exposed to radioactive iodides(43)(44).
2. Avoid exposure to radiation(22)(23)
People who exposed to the radiation therapy at a young age to treat certain cancer are at higher risk to develop thyroid cancer at later age. Extra precaution to prevent exposure the thyroid gland when X ray is taken.
3. Avoid Iodine deficiency(30)(31)
Increase Iodine intake from diet to prevent iodine deficiency cause of thyroid cancer.
4. Avoid certain chemical agents(28)(29)
Chemicals such as polychlorinated biphenyls and dioxins can increase risks of thyroid cancer
5. Lose weight
In an article published in the journal Cancer Epidemiology, Biomarkers and Prevention the meta-study indicated that the risk of thyroid cancer increases for obese men at roughly the same rate as it does for women(45), but in men over the age of 45 years and women under 45 years, a BMI in the obesity range was linked to a lower incidence of malignancy(46).
5. Avoid chlorine and fluoride(47)
Chlorine and fluoride are chemically related to iodine and they can block iodine receptors
6. Etc.
G.2. Diet
1. Cruciferous vegetables(48)
Cruciferous vegetables such as cauliflower, broccoli, cabbage, etc. beside containing high amount of antioxidants, it also contains high amount phytonutrients which have shown to prevent the onset and halt the progression of certain cancers. Unfortunately, according to National Cancer Center, intake of Cruciferous vegetables is associated with risk of thyroid cancer(49).
2. Green tea
Epigallocatechin gallate found in green tea, showed to reduce thyroid cell motility and migration associated with modulation in the expression of several proteins involved in cell adhesion and reorganization of actin proteins(50).
3. Garlic
Garlic consumption is associated to reduced risk of common cancers, according an analysis of several case-controlled studies in Europe. Diallyl sulfide, a phytochemical found in garlic showed to induces growth inhibition and apoptosis of anaplastic thyroid cancer cells by mitochondrial signaling pathway(51), with functions of cell regulatory and signaling events, in the responses of cells multiplication, communication, cell proliferation and death(52).
4. Tomato
Many studies showed that antioxidant lycopene in tomato inhibits cancer cell growth and exhibits apoptosis, in inducing cell death. Unfortunately, high consumption of tomatoes (> 200/year) was associated with an elevated risk of > 2.5 for malignant tumor(53)
5. Organic Soy
6. Etc.
G.3. Nutritional supplements
1. Free radicals scavengers
Vitamin A, C, E are free radical scavengers enhanced the immune system against the forming of free radicals and prevent the alternation of cell DNA cause of abnormal cell growth(56). According to Fujita Health University School of Medicine, patients tissues with papillary carcinoma and follicular adenoma were found to contain significantly higher concentrations of xanthine oxidase (XOD) and gluthathione peroxidase (GSH-PX), in comparison to those in the normal thyroid tissues(57)
2. Modified citrus pectin
Strong evidences in studies found that Modified citrus pectin may help block the growth and metastasis of solid tumors(58)(59).
3. Selenium
Selenium may haves a protective effect on various stages of cancer(60). In a study in large groups of people, researchers found that in areas of the world where selenium levels in the soil are high, death rates from cancer are significantly lower than in areas where selenium levels are low(61). According to Weill Medical College of Cornell University, selenium inhibits thyroid cancer cell proliferation through upregulation of family of gene (GADD)responsible for growth arrest DNA damage(62).
5. Etc.
H.Treatments
H.1. In conventional medicine
Treatment of thyroid cancer not only depends on the stage, grade but also ages of the patient. Thyroid cancer occurs in older people tend to be aggressive, while in young adulthood and adolescence are curative.
1. Surgery
The objective of the surgery is to cure, especial in the younger age group. If the cancer is a slow-grow and in the early stage, in most case after the thyroid gland was removed, patient will need to take thyroxine tablets for the rest of his/her life. According to Northwast University, total thyroidectomy showed to lower recurrence rates and improved survival compared with lobectomy(63). If the cancer has spread to the nearby lymph nodes, the lymph nodes are also removed in the same surgery.
If your blood indicates that you have an elevation of calcitoninis, an inherited medullary thyroid cancer, then surgery may be only treatment(64).
2. Radioactive Iodine
Radioactive iodine usually is also used to treat hyperthyroidism(65). In case of thyroid cancer, treatment of radioactive iodine showed to improve the survivors rate through reduction of its spreading(66). The use of radioactive therapy must follow certain guideline(67).
Since it is highly radioactive, avoid exposing radioactivity to your family members or other people are absolutely necessary. There are some instructions that you must follow for the first 5 days after your treatment(68).
a. Drink plenty of fluids.
b. Avoid contact with children and pregnant women.
c. Sleep in your own room.
d. Use separate towels, face cloths, and sheets.
e. Wash above and your personal clothing separately for 5 days
f. Etc.
For more information of http://www.eanm.org/publications/guidelines/gl_radio_ther_259_883.pdf
3. Radiotherapy
a. Radiation may be used for stages II, III, and IV to kill any cancer cells remaining in the body, after surgery. By using high-energy x-rays or other types of radiation(70)(71), radiation therapy kills the cancer cells and keep them from growing or regrowing.
b. Side effects
b.1. Fatigue
b.2. Chest pain
b.3. Heart problem
b.4. Short of breath
b.5. Skin discoloration or pinkness, irritation.
b.6. Etc.
In elder, and if the cancer has spread, chemotherapy may be recommended. Combination of chemotherapy after treatment of radiotherapy(72) or surgery and intensive radiotherapy have resulted in long-term survival in patients in most cases of invasive thyroid cancer,(73).
4. Chemotherapy
Chemotherapy is most used to treat with advance stage of cancer combined with radio therapy(74), as cancer has spread to a distant parts of the body, by using drugs taken by mouth or injected into a vein or muscle of the patient to stop the growth of or to kill cancer cells(75).
b. Side effects
b.1. Nausea
b.2. Vomiting
b.3. Hair loss
b.4. Fatigue
b.5. Anemia
b.6. Mouth sores taste and smell changes
b.7. Infection
b.8. Etc.
H.2. Herbal medicine
1. Aloe
Antioxidant, antiproliferative, and immunostimulatory found in aloe may be next potential herbal medicine for treatment of cancers(76) due to its chemical compounds, such as acemannan(77), and di(2-ethylhexyl)phthalate (DEHP)(78)(79) in immunomodulating and anticancer effects.
2. Absinthe
Absinthe is also known as Wormwood, a distilled, highly alcoholic beverage flowers extracted from leaves of the herb Artemisia absinthium. According to studies, wormwood maybe used as a promising potential treatment for cancer treatment(80)(81).
3. Fenugreek
Fenugreek is used both as a herb (the leaves) and as a spice (the seed), genus Trigonella, belonging to family Fabaceae. Studies have shown that fenugreek exhibits chemopreventive properties against certain cancers(82)(83)(84).
4. Devil's Claw
The extract of Harpagophytum procumbens, in vitro demonstrated anticancer effects against several cancer cell lines(85)(86) and has been reported to be effective in the treatment of lymphoma cancer, according to a study conducted by K. S. Wilson, M.D., published in the journal "Current Oncology" in August 2009.
5. Celandine
Celandine is a herbaceous perennial plant, genus Chelidonium, belonging to the family Papaveraceae, native to Europe and western Asia and introduced widely in North America. According to studies, the herb has demonstrated cytotoxicity activity as a natural resource for treatment potential antitumor agents(87.) Ukrain (Ukrain is an anticancer drug based on the extract of Celandine), in a systematic review of randomised clinical trials, showed a potential as an anticancer drug(88)(89)(90)
6. Etc
H.3. Traditional Chinese medicine
1. Pu Kong Yin (Dandelion Root)
According to numbers of studies(91)(92)(93), dandelion root extract showed to exhibit its anti cancer effects in some cancer cell lines.
In drug-resistant human melanoma cells, dandelion root extract induced apoptosis of chemoresistant melanoma, without toxicity to healthy cells(94).
2. Qing hao
Qing hao, also known as wormwood, a Chinese folk medicine may be used as a promising potential treatment for cancer(80)(81).
3. Jie Geng
Aponins in Jie Geng showed to exhibit a very significantly augment of the cytotoxicity of immunotoxins and other targeted toxins directed against human cancer cells(95)(96)(97).
4. Gan Cao
Gan Cao is also known as Licorice root. The herbs showed to inhibit progression of certain cancer cell lines(98)(99)(100). In-vitro, saponins in Gan Cao stimulates the immune system and inhibits Epstein-Barr virus expression and possess anti-cancer activities(101).
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References
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Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Thyroid disease
Thyroid disease is defined as a condition of malfunction of thyroid.
Thyroid disease: Thyroid Cancer
Thyroid cancer is a condition in which the cells in the thyroid gland have become cancerous.Types of thyroid cancer
The most common types of thyroid cancer include
1. Papillary thyroid cancer
Papillary thyroid cancer, the most common type of thyroid cancer with high proclivity for recurrence or persistence found in patients with BRAF(a protein, involved in directing cell growth) mutation(1), makes up about 80 percent of all thyroid cancers. The cancer tends to develop in the women age group between 30-40 and grows slowly. Papillary thyroid cancer can be cured if diagnosed early.
2. Follicular thyroid cancer
Follicular thyroid cancer, a slowly grew cancer with peak onset between ages 40 to 60, and second most common thyroid cancer, makes up about 15 percent of all cases with mostly in women over 50 years of age(2). Follicular thyroid cancer can be treated successful, if diagnosed early, depending to site of metastasis, histology, and iodine avidity of the metastasis(3).
3. Medullary thyroid cancer
Medullary thyroid cancer, third most common thyroid cancer made up about 5 percent of all cases(4), arises from thyroid hormone producing cells with abnormally high levels of calcitonin(6). Medullary thyroid cancer tends to grow slowly but can spread to distant parts of the body, if not treated early, depending to interdisciplinary communication, and patient education and encouragement of enhance compliance and safety, etc.(5).
4. Anaplastic thyroid cancer
Anaplastic thyroid cancer the rare case of thyroid cancer, makes up less than 2 percent of all cases(7). The cancer cells tend to grow and spread very quickly responsible for the majority of death from all thyroid cancers and have a median survival of 6 months(7). Anaplastic thyroid cancer is deadly, with only 10% of survival rate, and median survival of 3 to 5 months(8) after it is diagnosed.
A. Symptoms
1. Lump in the neck(9)(10)(11)
Due to uncontrollable cells growth and only 5% of this lumps are found to be cancerous.
2. Enlarged lymph node(12)(14)
Cancer has invaded the lymph nodes and its surrounding
3. Change of voice(13)
Hoarseness or difficulty speaking in a normal voice as the tumor has affected the voice-box region.
4. Pain or discomfort in the throat or neck(15)(16).
5. Problem of swallowing(17)
As a result of tumor has affected the esophagus or of enlarged lymph node
6. Difficult breathing(18)
Cancer may have invaded the lung or may affect either the upper or lower of respiratory track or due to enlarged lymph node
7. Other local compressive symptoms, such as dysphagia, dysphonia, stridor, neck tenderness and dyspnea(19)
B. Causes and risk factors
1. Age
Risk of thyroid cancer increases with age(20).
2. Gender
Women are twice at risk to develop thyroid cancer than men(20).
3. Race
In US, according to statistic, Caucasians are at greater risk than African Americans to develop thyroid cancer(21). Women in ethnic Asian/Pacific Islander and Hispanic origin are associated to higher risk of thyroid cancer(21).
5. Exposure to radiation(22)(23)
People who exposed to the radiation therapy at a young age for treatment of certain cancer are at higher risk to develop thyroid cancer at later age(24).
6. Family history(25)
Increased risk of thyroid cancer if your direct family has a history of thyroid cancer(26).
7. Chronic goiter(27)
Risk of thyroid cancer increased if you have a history of enlargement of the thyroid gland.
8. Exposure to certain chemical agents(28)(29)
In a study by Copenhagen researchers, the effect of chemicals such as polychlorinated biphenyls and dioxins on the thyroid. is associated with the of correlation between chemicals and increased TSH cause of an increased opportunity for mutations and the development of cancer.
9. Low level of iodine
People with life-long iodine deficiency are more likely to develop thyroid cancer(30)(31).
10. Heredity
People born with mutation in the RET proto-oncogene are at risk in developing medullary thyroid cancer (MTC)(32)(33).
11. Etc.
C. Diagnosis and tests
After family history and careful physical examination, If you have a family history of medullary thyroid cancer, blood test for calcitoninis is necessary
1. Blood test
The blood is to determine the levels of calcitoninis. Elevation of calcitoninis may be a sign of thyroid cancer(34).
2. Thyroid scan(35)
With the inject of asotope, your doctor can view the images capture and classify them, according the amount asotope of absorption by the thyroid gland. If the gland is actively taking up the isotope, ultrasound will show whether the abnormality is a cyst or not. Thyroid biopsy may be required to further assessment.
3. Thyroid biopsy(36)
In thyroid biopsy, a sample of the effected area is taken by a thin needle instrument (thin needle aspirate) under local anesthesia and examined by a pathologist under microscopy to view the type and stage of the cancer.
4. CT Scan (computerized tomography)(37)(38)
A CT scan generates is a large series of two-dimensional X-ray images taken around a single axis of rotation, to create a three-dimensional picture of the inside of the body in details.The pictures are viewed by your doctor to see the extent of the tumors abnormalities, such as spreading of cancer to the nearby structure and lymph nodes.
5. Etc.
D. Grades
The Grades of Thyroid cancer are depending to the tendency of spreading. Low grade cancers(39) in most cases, usually grow more slowly and are less likely to spread while high grade cancer indicates otherwise(40)(41).
E. Stages(42)
Thyroid cancer is classified as 5 stages
1. Stage 0
If the cancerous cell have not penetrated in deeper tissue but in the surface of the thyroid lining.
2. Stage I
In stage I, The cancerous cells are no longer in the surface but have invaded into deep thyroid lining, but still completely inside the thyroid gland.
Stage IA
The cancer is not ≤ 3 mm (1/8 inch) deep and ≤ 7 mm (1/4 inch) wide.In stage I, The cancerous cells are no longer in the surface but have invaded into deep thyroid lining, but still completely inside the thyroid gland.
Stage IA
a.1. Stage IA1:
The spreading is not less than 3mm(1/8 inch) deep and & less than 7mm (1/4 inch) wide.
a.2. Stage IA2: The invasion area is ≥ 3 mm but ≤ 5 mm (about 1/5 inch) deep and & less than 7 mm (about 1/4 inch) wide.
b. Stage IB:
The cancer in this stage have invaded the connective tissue, & less than 5mm (1/5 inch).
b.1. Stage IB1:
Cancer is 4 cm large (1 3/4 inches).
b.2. Stage IB2:
Cancer is ≥ 4 cm (1 3/4 inches) but & less than 5cm (1/5 inch)
3. Stage II
In stage II, the cancerous cells have spread to distant tissues, but is still within the thyroid gland.
4. Stage III
In this stage, cancerous cells has spread to the tissues immediately surrounding the thyroid gland
5. Stage IV
In this stage, cancerous cells has spread to the tissues immediately outside of the thyroid gland, other distant parts of the body.
G. Prevention
G.1. What to avoid
1. Potassium Iodide
Potassium Iodide (KI) is one of the drug used to absorb radioactive iodine cause of thyroid disease and cancer. Today it has been used worldwide to prevent thyroid cancer in people who are exposed to radioactive iodides(43)(44).
2. Avoid exposure to radiation(22)(23)
People who exposed to the radiation therapy at a young age to treat certain cancer are at higher risk to develop thyroid cancer at later age. Extra precaution to prevent exposure the thyroid gland when X ray is taken.
3. Avoid Iodine deficiency(30)(31)
Increase Iodine intake from diet to prevent iodine deficiency cause of thyroid cancer.
4. Avoid certain chemical agents(28)(29)
Chemicals such as polychlorinated biphenyls and dioxins can increase risks of thyroid cancer
5. Lose weight
In an article published in the journal Cancer Epidemiology, Biomarkers and Prevention the meta-study indicated that the risk of thyroid cancer increases for obese men at roughly the same rate as it does for women(45), but in men over the age of 45 years and women under 45 years, a BMI in the obesity range was linked to a lower incidence of malignancy(46).
5. Avoid chlorine and fluoride(47)
Chlorine and fluoride are chemically related to iodine and they can block iodine receptors
6. Etc.
G.2. Diet
1. Cruciferous vegetables(48)
Cruciferous vegetables such as cauliflower, broccoli, cabbage, etc. beside containing high amount of antioxidants, it also contains high amount phytonutrients which have shown to prevent the onset and halt the progression of certain cancers. Unfortunately, according to National Cancer Center, intake of Cruciferous vegetables is associated with risk of thyroid cancer(49).
2. Green tea
Epigallocatechin gallate found in green tea, showed to reduce thyroid cell motility and migration associated with modulation in the expression of several proteins involved in cell adhesion and reorganization of actin proteins(50).
3. Garlic
Garlic consumption is associated to reduced risk of common cancers, according an analysis of several case-controlled studies in Europe. Diallyl sulfide, a phytochemical found in garlic showed to induces growth inhibition and apoptosis of anaplastic thyroid cancer cells by mitochondrial signaling pathway(51), with functions of cell regulatory and signaling events, in the responses of cells multiplication, communication, cell proliferation and death(52).
4. Tomato
Many studies showed that antioxidant lycopene in tomato inhibits cancer cell growth and exhibits apoptosis, in inducing cell death. Unfortunately, high consumption of tomatoes (> 200/year) was associated with an elevated risk of > 2.5 for malignant tumor(53)
5. Organic Soy
In
laboratory studies, saponins have shown the ability to inhibit the
reproduction of cancer cells and slowed the growth of tumors in several different tissues(54).
According
to Dankook University, Combination of Photodynamic therapy (PDT) and
genistein found in organic soy, showed to induce apoptosis in SNU 80
thyroid cancer cell line much higher in comparison of individual
treatment with genistein or PDT(55).
6. Etc.
G.3. Nutritional supplements
1. Free radicals scavengers
Vitamin A, C, E are free radical scavengers enhanced the immune system against the forming of free radicals and prevent the alternation of cell DNA cause of abnormal cell growth(56). According to Fujita Health University School of Medicine, patients tissues with papillary carcinoma and follicular adenoma were found to contain significantly higher concentrations of xanthine oxidase (XOD) and gluthathione peroxidase (GSH-PX), in comparison to those in the normal thyroid tissues(57)
2. Modified citrus pectin
Strong evidences in studies found that Modified citrus pectin may help block the growth and metastasis of solid tumors(58)(59).
3. Selenium
Selenium may haves a protective effect on various stages of cancer(60). In a study in large groups of people, researchers found that in areas of the world where selenium levels in the soil are high, death rates from cancer are significantly lower than in areas where selenium levels are low(61). According to Weill Medical College of Cornell University, selenium inhibits thyroid cancer cell proliferation through upregulation of family of gene (GADD)responsible for growth arrest DNA damage(62).
5. Etc.
H.Treatments
H.1. In conventional medicine
Treatment of thyroid cancer not only depends on the stage, grade but also ages of the patient. Thyroid cancer occurs in older people tend to be aggressive, while in young adulthood and adolescence are curative.
1. Surgery
The objective of the surgery is to cure, especial in the younger age group. If the cancer is a slow-grow and in the early stage, in most case after the thyroid gland was removed, patient will need to take thyroxine tablets for the rest of his/her life. According to Northwast University, total thyroidectomy showed to lower recurrence rates and improved survival compared with lobectomy(63). If the cancer has spread to the nearby lymph nodes, the lymph nodes are also removed in the same surgery.
If your blood indicates that you have an elevation of calcitoninis, an inherited medullary thyroid cancer, then surgery may be only treatment(64).
2. Radioactive Iodine
Radioactive iodine usually is also used to treat hyperthyroidism(65). In case of thyroid cancer, treatment of radioactive iodine showed to improve the survivors rate through reduction of its spreading(66). The use of radioactive therapy must follow certain guideline(67).
Since it is highly radioactive, avoid exposing radioactivity to your family members or other people are absolutely necessary. There are some instructions that you must follow for the first 5 days after your treatment(68).
a. Drink plenty of fluids.
b. Avoid contact with children and pregnant women.
c. Sleep in your own room.
d. Use separate towels, face cloths, and sheets.
e. Wash above and your personal clothing separately for 5 days
f. Etc.
For more information of http://www.eanm.org/publications/guidelines/gl_radio_ther_259_883.pdf
3. Radiotherapy
a. Radiation may be used for stages II, III, and IV to kill any cancer cells remaining in the body, after surgery. By using high-energy x-rays or other types of radiation(70)(71), radiation therapy kills the cancer cells and keep them from growing or regrowing.
b. Side effects
b.1. Fatigue
b.2. Chest pain
b.3. Heart problem
b.4. Short of breath
b.5. Skin discoloration or pinkness, irritation.
b.6. Etc.
In elder, and if the cancer has spread, chemotherapy may be recommended. Combination of chemotherapy after treatment of radiotherapy(72) or surgery and intensive radiotherapy have resulted in long-term survival in patients in most cases of invasive thyroid cancer,(73).
4. Chemotherapy
Chemotherapy is most used to treat with advance stage of cancer combined with radio therapy(74), as cancer has spread to a distant parts of the body, by using drugs taken by mouth or injected into a vein or muscle of the patient to stop the growth of or to kill cancer cells(75).
b. Side effects
b.1. Nausea
b.2. Vomiting
b.3. Hair loss
b.4. Fatigue
b.5. Anemia
b.6. Mouth sores taste and smell changes
b.7. Infection
b.8. Etc.
H.2. Herbal medicine
1. Aloe
Antioxidant, antiproliferative, and immunostimulatory found in aloe may be next potential herbal medicine for treatment of cancers(76) due to its chemical compounds, such as acemannan(77), and di(2-ethylhexyl)phthalate (DEHP)(78)(79) in immunomodulating and anticancer effects.
2. Absinthe
Absinthe is also known as Wormwood, a distilled, highly alcoholic beverage flowers extracted from leaves of the herb Artemisia absinthium. According to studies, wormwood maybe used as a promising potential treatment for cancer treatment(80)(81).
3. Fenugreek
Fenugreek is used both as a herb (the leaves) and as a spice (the seed), genus Trigonella, belonging to family Fabaceae. Studies have shown that fenugreek exhibits chemopreventive properties against certain cancers(82)(83)(84).
4. Devil's Claw
The extract of Harpagophytum procumbens, in vitro demonstrated anticancer effects against several cancer cell lines(85)(86) and has been reported to be effective in the treatment of lymphoma cancer, according to a study conducted by K. S. Wilson, M.D., published in the journal "Current Oncology" in August 2009.
5. Celandine
Celandine is a herbaceous perennial plant, genus Chelidonium, belonging to the family Papaveraceae, native to Europe and western Asia and introduced widely in North America. According to studies, the herb has demonstrated cytotoxicity activity as a natural resource for treatment potential antitumor agents(87.) Ukrain (Ukrain is an anticancer drug based on the extract of Celandine), in a systematic review of randomised clinical trials, showed a potential as an anticancer drug(88)(89)(90)
6. Etc
H.3. Traditional Chinese medicine
1. Pu Kong Yin (Dandelion Root)
According to numbers of studies(91)(92)(93), dandelion root extract showed to exhibit its anti cancer effects in some cancer cell lines.
In drug-resistant human melanoma cells, dandelion root extract induced apoptosis of chemoresistant melanoma, without toxicity to healthy cells(94).
2. Qing hao
Qing hao, also known as wormwood, a Chinese folk medicine may be used as a promising potential treatment for cancer(80)(81).
3. Jie Geng
Aponins in Jie Geng showed to exhibit a very significantly augment of the cytotoxicity of immunotoxins and other targeted toxins directed against human cancer cells(95)(96)(97).
4. Gan Cao
Gan Cao is also known as Licorice root. The herbs showed to inhibit progression of certain cancer cell lines(98)(99)(100). In-vitro, saponins in Gan Cao stimulates the immune system and inhibits Epstein-Barr virus expression and possess anti-cancer activities(101).
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References
(1) http://www.ncbi.nlm.nih.gov/pubmed/22932786
(2) http://www.ncbi.nlm.nih.gov/pubmed/25287965
(3) http://www.ncbi.nlm.nih.gov/pubmed/17705176
(4) http://www.ncbi.nlm.nih.gov/pubmed/25366585
(6) http://www.ncbi.nlm.nih.gov/pubmed/22564994
(7) http://www.ncbi.nlm.nih.gov/pubmed/25260367
(8) http://www.ncbi.nlm.nih.gov/pubmed/21772843
(9) http://www.ncbi.nlm.nih.gov/pubmed/24846559
(10) http://www.ncbi.nlm.nih.gov/pubmed/22531042
(11) http://www.ncbi.nlm.nih.gov/pubmed/24780013
(12) http://www.ncbi.nlm.nih.gov/pubmed/25197391
(13) http://www.ncbi.nlm.nih.gov/pubmed/24618295
(14) http://www.ncbi.nlm.nih.gov/pubmed/20713342
(15) http://www.ncbi.nlm.nih.gov/pubmed/21509150
(16) http://www.ncbi.nlm.nih.gov/pubmed/12548045
(17) http://www.ncbi.nlm.nih.gov/pubmed/8125784
(18) http://www.ncbi.nlm.nih.gov/pubmed/24944660
(19) http://www.ncbi.nlm.nih.gov/pubmed/18923370
(20) http://www.cancerresearchuk.org/cancer-info/cancerstats/types/thyroid/incidence/uk-thyroid-cancer-incidence-statistics
(21) http://cancer.emedtv.com/thyroid-cancer/thyroid-cancer-statistics.html
(22) http://www.ncbi.nlm.nih.gov/pubmed/21296564
(23) http://www.ncbi.nlm.nih.gov/pubmed/12852471
(24) http://www.ncbi.nlm.nih.gov/pubmed/23694687
(25) http://www.ncbi.nlm.nih.gov/pubmed/25361888
(26) http://www.ncbi.nlm.nih.gov/pubmed/22136209
(27) http://www.ncbi.nlm.nih.gov/pubmed/22075140
(28) http://www.ncbi.nlm.nih.gov/pubmed/10457919
(29) http://www.ncbi.nlm.nih.gov/pubmed/10457907
(30) http://www.ncbi.nlm.nih.gov/pubmed/12913034
(31) http://www.ncbi.nlm.nih.gov/pubmed/12762643
(32) http://www.ncbi.nlm.nih.gov/pubmed/16029119
(33) http://www.ncbi.nlm.nih.gov/pubmed/9167949
(34) http://www.ncbi.nlm.nih.gov/pubmed/23314540
(35) http://www.ncbi.nlm.nih.gov/pubmed/25318409
(36) http://www.ncbi.nlm.nih.gov/pubmed/20028902
(37) http://www.ncbi.nlm.nih.gov/pubmed/25210279
(38) http://www.ncbi.nlm.nih.gov/pubmed/24848831
(39) http://www.ncbi.nlm.nih.gov/pubmed/19209127
(40) http://www.ncbi.nlm.nih.gov/pubmed/25051728
(41) http://www.ncbi.nlm.nih.gov/pubmed/21969055
(42) http://www.thyca.org/about/types/
(43) http://www.ncbi.nlm.nih.gov/pubmed/23475155
(44) http://www.ncbi.nlm.nih.gov/pubmed/10832925
(45) http://www.ncbi.nlm.nih.gov/pubmed/22914989
(46) http://www.ncbi.nlm.nih.gov/pubmed/19415996
(47) http://www.enerex.ca/en/articles/chlorine-the-paradox
(48) http://www.ncbi.nlm.nih.gov/pubmed/25256273
(49) http://www.ncbi.nlm.nih.gov/pubmed/25136535
(50) http://www.ncbi.nlm.nih.gov/pubmed/23553645
(51) http://www.ncbi.nlm.nih.gov/pubmed/20219414
(52) http://www.ncbi.nlm.nih.gov/pubmed/15532704
(53) http://www.ncbi.nlm.nih.gov/pubmed/11048335
(54) http://www.ncbi.nlm.nih.gov/pubmed/20550961
(55) http://www.ncbi.nlm.nih.gov/pubmed/23143780
(56) http://www.ncbi.nlm.nih.gov/pubmed/17395018
(57) http://www.ncbi.nlm.nih.gov/pubmed/9288568
(58) http://www.ncbi.nlm.nih.gov/pubmed/23673419
(59) http://www.ncbi.nlm.nih.gov/pubmed/24460334
(60) http://www.ncbi.nlm.nih.gov/pubmed/24683040
(61) www.cancer.org
(62) http://www.ncbi.nlm.nih.gov/pubmed/20043261
(63) http://www.ncbi.nlm.nih.gov/pubmed/17717441
(64) http://www.ncbi.nlm.nih.gov/pubmed/17915054
(65) http://www.ncbi.nlm.nih.gov/pubmed/25285284
(66) http://www.ncbi.nlm.nih.gov/pubmed/19281429
(67) http://www.eanm.org/publications/guidelines/gl_radio_ther_259_883.pdf
(68) http://www.stjoes.ca/patients-visitors/patient-education/f-j/PD%206177%20I131RadioactiveIodineTherapySJH-trh.pdf
(69) http://www.ncbi.nlm.nih.gov/pubmed/24137562
(70) http://www.ncbi.nlm.nih.gov/pubmed/16542796
(71) http://www.ncbi.nlm.nih.gov/pubmed/19623515
(72) http://www.ncbi.nlm.nih.gov/pubmed/24393873
(73) http://www.ncbi.nlm.nih.gov/pubmed/22311136
(74) http://www.ncbi.nlm.nih.gov/pubmed/25396774
(75) http://www.ncbi.nlm.nih.gov/pubmed/24092989
(76) http://www.ncbi.nlm.nih.gov/pubmed/22516934
(77) http://www.ncbi.nlm.nih.gov/pubmed/8956975
(78) http://www.ncbi.nlm.nih.gov/pubmed/24454344
(79) http://www.ncbi.nlm.nih.gov/pubmed/24646702
(80) http://www.ncbi.nlm.nih.gov/pubmed/25295671
(81) http://www.ncbi.nlm.nih.gov/pubmed/25370606
(82) http://www.ncbi.nlm.nih.gov/pubmed/24973886
(83) http://www.ncbi.nlm.nih.gov/pubmed/24679057
(84) http://www.ncbi.nlm.nih.gov/pubmed/23110539
(85) http://www.ncbi.nlm.nih.gov/pubmed/15630188
(86) http://www.ncbi.nlm.nih.gov/pubmed/15639337
(87) http://www.ncbi.nlm.nih.gov/pubmed/24312877
(88) http://www.ncbi.nlm.nih.gov/pubmed/23991464
(89) http://www.ncbi.nlm.nih.gov/pubmed/23302993
(90) http://www.ncbi.nlm.nih.gov/pubmed/20693969
(91) http://www.ncbi.nlm.nih.gov/pubmed/22647733
(92) http://www.ncbi.nlm.nih.gov/pubmed/22363452
(93) http://www.ncbi.nlm.nih.gov/pubmed/20849941
(94) http://www.ncbi.nlm.nih.gov/pubmed/21234313
(95) http://www.ncbi.nlm.nih.gov/pubmed/25250884
(96) http://www.ncbi.nlm.nih.gov/pubmed/25019244
(97) http://www.ncbi.nlm.nih.gov/pubmed/24854572
(98) http://www.ncbi.nlm.nih.gov/pubmed/15313200
(99) http://www.ncbi.nlm.nih.gov/pubmed/24998545
(100) http://www.ncbi.nlm.nih.gov/pubmed/24944769
(101) http://www.weiku.com/products/13593181/Radix_Glycyrrhiza_gan_cao_.html
Endometriosis: The Effects of Peanuts(Revised edition with references)
By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
During the last stage of the menstrual cycle, normally a layer of endometriosis lining on the inside of the uterus is expelled, known as menstruation blood, instead some of the endometriosis tissues grow somewhere in the body to cause endometriosis. Endometriosis also react to hormone signals of the monthly menstrual cycle, by building and breaking up tissues and eliminating them through menstrual period.
Peanuts is belong to the legume related to the bean family and first cultivated in the in the Chaco region of Paraguay and Bolivia.
2. Sugars
3. Dietary fiber
4. Fat
a. saturated
b. monounsaturated
c. polyunsaturated
5. Protein
6. Tryptophan
7. Threonine
8. Isoleucine
9. Leucine
10. Lysine
11. Methionine
12. Cystine
13. Phenylalanine
14. Tyrosine
15. Valine
16. Arginine
17. Histidine
18. Alanine
19. Aspartic acid
20. Glutamic acid
21. Glycine
22. Proline
23. Serine
24. Water
25. Thiamine (Vit. B1)
26. Riboflavin (Vit. B2)
27. Niacin (Vit. B3)
28. Pantothenic acid (B5)
29. Vitamin B6
30. Folate (Vit. B9)
31. Calcium
32. Iron
33. Magnesium
34. Phosphorus
35. Zinc
The effects
1. Menstrual cramp
Peanut contains high amount of essential acid that helps to increase the liver in protein and fat metabolism(2) leading to balance the hormone in the prostaglandins family(3) resulting in lessening the menstrual cramps(4) caused by over active of uterine muscles(1).
2. Protein and Coenzyme Q10
High sources of protein and coenezyme Q10 in peanut help to regulate the cell growth and cell duplication(5), thereby reducing the risk of cell abnormality such as tumors, cancers(6) an forming of endometrial cells in the abdomen.
3. Immune system
The antioxidant property in peanut helps the immune system in fighting and winning the battle against the abnormal forming of endometriosis caused inflammation(8) in the body(7).
4. Niacin
Since niacin in the peanut increases the blood flow in the body including the abdominal region, through improvement of lipid profile, it calms and relaxes the muscle(10) in the abdomen resulting in lessening the menstrual pain caused by over active abdominal muscles(10).
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will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
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Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
References
(1) Endometriosis, dysmenorrhoea and diet by Hansen SO1, Knudsen UB.(PubMed)
(2) Beneficial effects of enteral fat administration on liver dysfunction, liver lipid accumulation, and protein metabolism in septic rats by Hayashi N1, Kashiwabara N, Yoshihara D, Takeshita Y, Handa H, Yanai M, Maeda J, Yamakawa M.(PubMed)
(3) Synthesis of prostaglandins and thromboxane B2 by cholesterol-fed rabbits by Wang T1, Falardeau P, Powell WS.(PubMed)
(4) Beneficial effects of enteral fat administration on liver dysfunction, liver lipid accumulation, and protein metabolism in septic rats by Hayashi N1, Kashiwabara N, Yoshihara D, Takeshita Y, Handa H, Yanai M, Maeda J, Yamakawa M.(PubMed)
(5) Coenzyme Q10 protects Pc12 cells from cisplatin-induced DNA damage and neurotoxicity by da Silva Machado C1, Mendonça LM, Venancio VP, Bianchi ML, Antunes LM.(PubMed)
(6) A randomized, double-blind, placebo-controlled study of oral coenzyme Q10 to relieve self-reported treatment-related fatigue in newly diagnosed patients with breast cancer by Lesser GJ1, Case D, Stark N, Williford S, Giguere J, Garino LA, Naughton MJ, Vitolins MZ, Lively MO, Shaw EG; Wake Forest University Community Clinical Oncology Program Research Base.(PubMed)
(7) Coenzyme Q10 and immunity: A case report and new implications for treatment of recurrent infections in metabolic diseases by Farough S1, Karaa A2, Walker MA3, Slate N4, Dasu T5, Verbsky J5, Fusunyan R4, Canapari C4, Kinane TB4, Van Cleave J4, Sweetser DA4, Sims KB3, Walter JE4.(PubMed)
(8) Functions of coenzyme Q10 in inflammation and gene expression by Schmelzer C1, Lindner I, Rimbach G, Niklowitz P, Menke T, Döring F.(PubMed)
(9) Niacin improves lipid profile but not endothelial function in patients with coronary artery disease on high dose statin therapy by Philpott AC1, Hubacek J, Sun YC, Hillard D, Anderson TJ.(PubMed)
(10) Role of prostaglandin D2 and the autonomic nervous system in niacin-induced flushing by Parson HK1, Harati H, Cooper D, Vinik AI.(PubMed)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
During the last stage of the menstrual cycle, normally a layer of endometriosis lining on the inside of the uterus is expelled, known as menstruation blood, instead some of the endometriosis tissues grow somewhere in the body to cause endometriosis. Endometriosis also react to hormone signals of the monthly menstrual cycle, by building and breaking up tissues and eliminating them through menstrual period.
Peanuts is belong to the legume related to the bean family and first cultivated in the in the Chaco region of Paraguay and Bolivia.
Nutrients
1. Carbohydrates2. Sugars
3. Dietary fiber
4. Fat
a. saturated
b. monounsaturated
c. polyunsaturated
5. Protein
6. Tryptophan
7. Threonine
8. Isoleucine
9. Leucine
10. Lysine
11. Methionine
12. Cystine
13. Phenylalanine
14. Tyrosine
15. Valine
16. Arginine
17. Histidine
18. Alanine
19. Aspartic acid
20. Glutamic acid
21. Glycine
22. Proline
23. Serine
24. Water
25. Thiamine (Vit. B1)
26. Riboflavin (Vit. B2)
27. Niacin (Vit. B3)
28. Pantothenic acid (B5)
29. Vitamin B6
30. Folate (Vit. B9)
31. Calcium
32. Iron
33. Magnesium
34. Phosphorus
35. Zinc
36. Etc.
1. Menstrual cramp
Peanut contains high amount of essential acid that helps to increase the liver in protein and fat metabolism(2) leading to balance the hormone in the prostaglandins family(3) resulting in lessening the menstrual cramps(4) caused by over active of uterine muscles(1).
2. Protein and Coenzyme Q10
High sources of protein and coenezyme Q10 in peanut help to regulate the cell growth and cell duplication(5), thereby reducing the risk of cell abnormality such as tumors, cancers(6) an forming of endometrial cells in the abdomen.
3. Immune system
The antioxidant property in peanut helps the immune system in fighting and winning the battle against the abnormal forming of endometriosis caused inflammation(8) in the body(7).
4. Niacin
Since niacin in the peanut increases the blood flow in the body including the abdominal region, through improvement of lipid profile, it calms and relaxes the muscle(10) in the abdomen resulting in lessening the menstrual pain caused by over active abdominal muscles(10).
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple WaySuper foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
References
(1) Endometriosis, dysmenorrhoea and diet by Hansen SO1, Knudsen UB.(PubMed)
(2) Beneficial effects of enteral fat administration on liver dysfunction, liver lipid accumulation, and protein metabolism in septic rats by Hayashi N1, Kashiwabara N, Yoshihara D, Takeshita Y, Handa H, Yanai M, Maeda J, Yamakawa M.(PubMed)
(3) Synthesis of prostaglandins and thromboxane B2 by cholesterol-fed rabbits by Wang T1, Falardeau P, Powell WS.(PubMed)
(4) Beneficial effects of enteral fat administration on liver dysfunction, liver lipid accumulation, and protein metabolism in septic rats by Hayashi N1, Kashiwabara N, Yoshihara D, Takeshita Y, Handa H, Yanai M, Maeda J, Yamakawa M.(PubMed)
(5) Coenzyme Q10 protects Pc12 cells from cisplatin-induced DNA damage and neurotoxicity by da Silva Machado C1, Mendonça LM, Venancio VP, Bianchi ML, Antunes LM.(PubMed)
(6) A randomized, double-blind, placebo-controlled study of oral coenzyme Q10 to relieve self-reported treatment-related fatigue in newly diagnosed patients with breast cancer by Lesser GJ1, Case D, Stark N, Williford S, Giguere J, Garino LA, Naughton MJ, Vitolins MZ, Lively MO, Shaw EG; Wake Forest University Community Clinical Oncology Program Research Base.(PubMed)
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#Healthy #recipe for Busy #Mom: #Veggie-Load #salad Rolls
Posted By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Recipe contributed by Everything Busy Moms' Cook Book By Susan Whetzel Published by Adamsmedia. You can view its website at www.everything.com.
Serves 4
Ingredients
1/3 cup soy sauce
1 tablespoon white vinegar
1tablespoon granulated sugar
1 tablespoon bottled minced garlic
1 tablespoon bottle chopped jalapeno peppers
11/2 cup packaged salad greens
1 cup cooked shrimp
1/4 cup chopped fresh Thai basil leaves
8 vegetable-favored tortilla wrappers
1. In a small bowl, stir together the soy sauce, vinegar, sugar, garlic and jalapeno peppers.
2. In a separate bowl, stir together the salad greens, cooked shrimp and basil leaves.
3. Lay a tortilla wrapper on the cutting board in front of you. Place about h1/4 cup of shrimp and salad mix on the bottom half of the wrapper, being careful not to come to close to the edges.
4. Rollup the wrapper like a taco, tucking in the sides. Combine filling and roll up the remainder of the wrapper.
5. Serve the roll cold with soy dipping sauce.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to Healthy Foods Index http://kylejnorton.blogspot.ca/p/healthy-foods-index.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Recipe contributed by Everything Busy Moms' Cook Book By Susan Whetzel Published by Adamsmedia. You can view its website at www.everything.com.
Serves 4
Ingredients
1/3 cup soy sauce
1 tablespoon white vinegar
1tablespoon granulated sugar
1 tablespoon bottled minced garlic
1 tablespoon bottle chopped jalapeno peppers
11/2 cup packaged salad greens
1 cup cooked shrimp
1/4 cup chopped fresh Thai basil leaves
8 vegetable-favored tortilla wrappers
1. In a small bowl, stir together the soy sauce, vinegar, sugar, garlic and jalapeno peppers.
2. In a separate bowl, stir together the salad greens, cooked shrimp and basil leaves.
3. Lay a tortilla wrapper on the cutting board in front of you. Place about h1/4 cup of shrimp and salad mix on the bottom half of the wrapper, being careful not to come to close to the edges.
4. Rollup the wrapper like a taco, tucking in the sides. Combine filling and roll up the remainder of the wrapper.
5. Serve the roll cold with soy dipping sauce.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to Healthy Foods Index http://kylejnorton.blogspot.ca/p/healthy-foods-index.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
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