By Kyle J. Norton
Indole-3-carbinol is a phytochemical in the class of Indoles, by the breaking down of the glucosinolate glucobrassicin, found abundantly in cabbage, kale, Brussels sprouts, rutabaga, mustard greens, broccoli, etc.
Cervical cancer is malignant neoplasm of the cervix uteri or cervical area caused by abnormal cells growth with alternation of cells DNA. According to the American Cancer Society's, in 2014, 12,360 new cases of invasive cervical cancer will be diagnosed with the death of 4,020 patients. The risk of cervical cancer is higher in Hispanic women followed by African-Americans, Asians and Pacific Islanders, and whites(a).
Depending to the stage and grade of the cancer, if the cancer is found in the early stahe, hysterectomy may not be needed. Other while after sugery, chemotherapy including Cisplatin, Fluorouracil (5-FU), Mitomycin, Paclitaxel, Ifosfamide, Carboplatin, Bevacizumab and radiotherapy may be necesary, but with certain side effects. Emerging suggestion of a healthy and balanced diet to improve high serum levels of antioxidants may reduce cervical neoplasia risk(b)(c) but other suggested that the role of diet and nutrition in the etiology of cervical cancer is not yet resolved(d) and Catalan Institute of Oncology study showed statistically nonsignificant inverse associations were also observed for leafy vegetables, root vegetables, garlic and onions, citrus fruits, vitamin C, vitamin E and retinol for invasive squamous cervical cancer (ISC)(e).
Dietary indole-3-carbinol (I3C) prevented the development of estrogen-enhanced cancers including breast, endometrial and cervical cancers(1) due to its antitumor activities associated not only with regulation of estrogen activity and metabolism, but also modulation of ER transcription activity(2) through both antiestrogenic and estrogenic activity(3). In human cervical cancer cells, in comparison to diindolylmethane (DIM), a major in vivo product of indole-3-carbinol (I3C), both I3C and DIM caused accumulation of DNA strand breaks in three cervical cancer cell lines. I3C increased apoptosis in target tissues in vivo.(4). In mice study, according to the The Long Island Campus of Albert Einstein College of Medicine, showed to prevent the cervical-vaginal cancer promoted high doses of estrogen in these mices(5) and increased PTEN expression in the cervical epithelium of the transgenic mouse in vivo(6)
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References
(a) Cerical cancer (Amerrican cancer society)
(b) Diet and serum micronutrients in relation to cervical neoplasia and cancer among low-income Brazilian women by Tomita LY1, Longatto Filho A, Costa MC, Andreoli MA, Villa LL, Franco EL, Cardoso MA; Brazilian Investigation into Nutrition and Cervical Cancer Prevention (BRINCA) Study Team.(PubMed)
(c) Associations of dietary dark-green and deep-yellow vegetables and fruits with cervical intraepithelial neoplasia: modification by smoking by Tomita LY1, Roteli-Martins CM, Villa LL, Franco EL, Cardoso MA; BRINCA Study Team.(PubMed)
(d) Diet and the risk of in situ cervical cancer among white women in the United States by Ziegler RG1, Jones CJ, Brinton LA, Norman SA, Mallin K, Levine RS, Lehman HF, Hamman RF, Trumble AC, Rosenthal JF, et al.(PubMed)
(e) Dietary factors and in situ and invasive cervical cancer risk in the European prospective investigation into cancer and nutrition study by González CA1, Travier N, Luján-Barroso L, Castellsagué X, Bosch FX, Roura E, Bueno-de-Mesquita HB, Palli D, Boeing H, Pala V, Sacerdote C, Tumino R, Panico S, Manjer J, Dillner J, Hallmans G, Kjellberg L, Sanchez MJ, Altzibar JM, Barricarte A, Navarro C, Rodriguez L, Allen N, Key TJ, Kaaks R, Rohrmann S, Overvad K, Olsen A, Tjønneland A, Munk C, Kjaer SK, Peeters PH, van Duijnhoven FJ, Clavel-Chapelon F, Boutron-Ruault MC, Trichopoulou A, Benetou V, Naska A, Lund E, Engeset D, Skeie G, Franceschi S, Slimani N, Rinaldi S, Riboli E.(PubMed)
(1) Indole-3-carbinol is a negative regulator of estrogen by Auborn KJ1, Fan S, Rosen EM, Goodwin L, Chandraskaren A, Williams DE, Chen D, Carter TH.(PubMed)
(2) Indole-3-carbinol is a negative regulator of estrogen receptor-alpha signaling in human tumor cells. by Meng Q1, Yuan F, Goldberg ID, Rosen EM, Auborn K, Fan S.(PubMed)
(3) Indolo[3,2-b]carbazole: a dietary-derived factor that exhibits both antiestrogenic and estrogenic activity by Liu H1, Wormke M, Safe SH, Bjeldanes LF.(PubMed)
(4) Indole-3-carbinol and diindolylmethane induce apoptosis of human cervical cancer cells and in murine HPV16-transgenic preneoplastic cervical epithelium by Chen DZ1, Qi M, Auborn KJ, Carter TH.(PubMed)
(5) Indole-3-carbinol prevents cervical cancer in human papilloma virus type 16 (HPV16) transgenic mice by Jin L1, Qi M, Chen DZ, Anderson A, Yang GY, Arbeit JM, Auborn KJ.(PubMed)
(6) Indole-3-carbinol prevents PTEN loss in cervical cancer in vivo by Qi M1, Anderson AE, Chen DZ, Sun S, Auborn KJ.(PubMed)
Thursday 31 July 2014
Obesity Complication of Varicose Vein
By Kyle J. Norton
Obesity is defined as a medical condition of excess body fat has accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.
B. How to calculate your BMI indexBMI= weight (kg)/ height (m2)
Varicose Vein is defined as a condition of enlarged and tortuous veins appearing blue and purple squiggly just under the skin. It can lead to blood flowing backwards, causing pain in standing or walking.
How Obesity associates with Varicose Vein
1. According to the study of "Associations of moderate and severe overweight with self-reported illness and medical care in Dutch adults" by Seidell JC, de Groot LC, van Sonsbeek JL, Deurenberg P, Hautvast JG., posted in PubMed, researchers wrote that In men, severe overweight was associated with hypertension, especially in men under 50 years of age. In women, severe overweight was associated with hypertension, diabetes, varicose veins, asthma/bronchitis, and hemorrhoids. Increased utilization of medical care and medications were also associated with severe overweight. For moderately overweight subjects, these associations were less clear or absent.
2. In a study of "Epidemiology and risk factors for varicose veins among older people: cross-sectional population study in the UK" by Clark A, Harvey I, Fowkes FG., posted in PubMed, researchers found that Trunk varices occur very commonly in older age groups with increasing age, obesity and possibly female sex as risk factors. Associations found with DVT and hypertension were based on history alone and must be interpreted with caution.
3. According to the abstract of "The risk of congestive heart failure is increased in persons with varicose veins" by Mäkivaara LA, Ahti TM, Luukkaala T, Hakama M, Laurikka JO., posted in PubMed, researchers filed the result that Marginally higher prevalence of CHF was found in persons with varicose veins than in those without (2.9% vs. 1.9%) with OR 1.6 (1.0-2.3) and sex and age adjusted OR 1.2 (0.8-1.9). The incidence of CHF was higher in subjects with varicose veins than in others (4.9 vs. 2.6 per 1000 person-years) with IDR 1.9 (1.1-2.9) and sex and age adjusted IOR 2.5 (1.4-4.6). The result was further adjusted for body mass index, arterial disease and hypertension; multi-adjusted IOR for the incidence of CHF by varicose veins was 2.1 (1.1-4.0).
4. In the study of "Incidence of varicose veins in Finland" byMäkivaara LA, Jukkola TM, Sisto T, Luukkaala T, Hakama M, Laurikka JO., posted in PubMed, researchers wrote that 157 individuals reported new varicose veins during the follow-up. The overall incidence was 13.5 per 1000 person years (8.5 for men and 19.2 for women). Female sex was an independent and statistically significant risk indicator of varicose veins (adjusted odds ratio, OR 2.4). The incidence was significantly higher at the age of 50-55 years (OR 1.6). Higher body mass index seemed to be related to higher risk of new varicose veins (OR 1.2-1.8), but the association failed to reach statistical significance. The level of education did not affect the incidence.
5. In the observation during a five-year follow-up period were studied of the study of "The risk of congestive heart failure is increased in persons with varicose veins" by Mäkivaara LA, Ahti TM, Luukkaala T, Hakama M, Laurikka JO., posted in Pubmed, researchers filed the conclusion that Our longitudinal observation is consistent with the hypothesis that persons with varicose veins have a higher risk of CHF which is not mediated through sex, age, overweight, arterial disease or hypertension.
6. Etc.
Treatments of Obesity and Varicose Vein
1. In the abstract of " [Varicose vein surgery and obesity--experience with a new Boazul cuff in leg circumference up to 90 cm]",[Article in German], by Hermanns HJ., posted in PubMed, researcher found that The use of the bloodless limb technique for varicose vein surgery is very comfortable, especially in cases of severe varicose veins and obesity. Maintenance of operation standards and utmost care of the cuffs lead to the successful use of this procedure.
2. According to the study of "Using the Boazul cuff to reduce blood loss in varicose vein surgery" by Robinson J, Macierewicz J, Beard JD., posted in PubMed, researchers concluded that use of the Boazul cuff significantly decreases the blood loss from the avulsion sites during routine varicose vein surgery, and may encourage the surgeon to perform more avulsions.
3. Etc.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
At Last! The Natural PCOS Diet
A Naturopath’s Easy Step-by-Step Guide to Overcome PCOS
by Qualified Australian Naturopath And Hormone Health Expert
Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Obesity is defined as a medical condition of excess body fat has accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.
B. How to calculate your BMI indexBMI= weight (kg)/ height (m2)
Varicose Vein is defined as a condition of enlarged and tortuous veins appearing blue and purple squiggly just under the skin. It can lead to blood flowing backwards, causing pain in standing or walking.
How Obesity associates with Varicose Vein
1. According to the study of "Associations of moderate and severe overweight with self-reported illness and medical care in Dutch adults" by Seidell JC, de Groot LC, van Sonsbeek JL, Deurenberg P, Hautvast JG., posted in PubMed, researchers wrote that In men, severe overweight was associated with hypertension, especially in men under 50 years of age. In women, severe overweight was associated with hypertension, diabetes, varicose veins, asthma/bronchitis, and hemorrhoids. Increased utilization of medical care and medications were also associated with severe overweight. For moderately overweight subjects, these associations were less clear or absent.
2. In a study of "Epidemiology and risk factors for varicose veins among older people: cross-sectional population study in the UK" by Clark A, Harvey I, Fowkes FG., posted in PubMed, researchers found that Trunk varices occur very commonly in older age groups with increasing age, obesity and possibly female sex as risk factors. Associations found with DVT and hypertension were based on history alone and must be interpreted with caution.
3. According to the abstract of "The risk of congestive heart failure is increased in persons with varicose veins" by Mäkivaara LA, Ahti TM, Luukkaala T, Hakama M, Laurikka JO., posted in PubMed, researchers filed the result that Marginally higher prevalence of CHF was found in persons with varicose veins than in those without (2.9% vs. 1.9%) with OR 1.6 (1.0-2.3) and sex and age adjusted OR 1.2 (0.8-1.9). The incidence of CHF was higher in subjects with varicose veins than in others (4.9 vs. 2.6 per 1000 person-years) with IDR 1.9 (1.1-2.9) and sex and age adjusted IOR 2.5 (1.4-4.6). The result was further adjusted for body mass index, arterial disease and hypertension; multi-adjusted IOR for the incidence of CHF by varicose veins was 2.1 (1.1-4.0).
4. In the study of "Incidence of varicose veins in Finland" byMäkivaara LA, Jukkola TM, Sisto T, Luukkaala T, Hakama M, Laurikka JO., posted in PubMed, researchers wrote that 157 individuals reported new varicose veins during the follow-up. The overall incidence was 13.5 per 1000 person years (8.5 for men and 19.2 for women). Female sex was an independent and statistically significant risk indicator of varicose veins (adjusted odds ratio, OR 2.4). The incidence was significantly higher at the age of 50-55 years (OR 1.6). Higher body mass index seemed to be related to higher risk of new varicose veins (OR 1.2-1.8), but the association failed to reach statistical significance. The level of education did not affect the incidence.
5. In the observation during a five-year follow-up period were studied of the study of "The risk of congestive heart failure is increased in persons with varicose veins" by Mäkivaara LA, Ahti TM, Luukkaala T, Hakama M, Laurikka JO., posted in Pubmed, researchers filed the conclusion that Our longitudinal observation is consistent with the hypothesis that persons with varicose veins have a higher risk of CHF which is not mediated through sex, age, overweight, arterial disease or hypertension.
6. Etc.
Treatments of Obesity and Varicose Vein
1. In the abstract of " [Varicose vein surgery and obesity--experience with a new Boazul cuff in leg circumference up to 90 cm]",[Article in German], by Hermanns HJ., posted in PubMed, researcher found that The use of the bloodless limb technique for varicose vein surgery is very comfortable, especially in cases of severe varicose veins and obesity. Maintenance of operation standards and utmost care of the cuffs lead to the successful use of this procedure.
2. According to the study of "Using the Boazul cuff to reduce blood loss in varicose vein surgery" by Robinson J, Macierewicz J, Beard JD., posted in PubMed, researchers concluded that use of the Boazul cuff significantly decreases the blood loss from the avulsion sites during routine varicose vein surgery, and may encourage the surgeon to perform more avulsions.
3. Etc.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
At Last! The Natural PCOS Diet
A Naturopath’s Easy Step-by-Step Guide to Overcome PCOS
by Qualified Australian Naturopath And Hormone Health Expert
Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Guacamole - The Dip for crispy nacho.
Recipe attributed to 30 minutes vegetarian recipes by Marie-laude Morin, Publisher Robert Rose at www,robertrose.ca
You will love the texture of this dip. Serve with crispy nacho.
Tip: If you like a touch of heat in your guacamole, add hot pepper sauce or a small amount of minced jalapeno pepper.
2 very ripe avocados 2
2 tbsp. freshly squeezed lemon juice 30mL
2 tsp. olive oil 10mL
1 tomato, seeded and diced 1
1 gloved garlic, minced 1
Pinch granulated sugar
Salt and freshly ground pepper
1. In food processor puree avocados until smooth. Or use a fork to smash avocado.
1. Stir in lemon juice, olive oil, tomato, garlic, sugar and salt and pepper to taste. Serve immediately as avocados have a tendency to blacken quickly. Serve 4.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
At Last! The Natural PCOS Diet
A Naturopath’s Easy Step-by-Step Guide to Overcome PCOS
by Qualified Australian Naturopath And Hormone Health Expert
Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
You will love the texture of this dip. Serve with crispy nacho.
Tip: If you like a touch of heat in your guacamole, add hot pepper sauce or a small amount of minced jalapeno pepper.
2 very ripe avocados 2
2 tbsp. freshly squeezed lemon juice 30mL
2 tsp. olive oil 10mL
1 tomato, seeded and diced 1
1 gloved garlic, minced 1
Pinch granulated sugar
Salt and freshly ground pepper
1. In food processor puree avocados until smooth. Or use a fork to smash avocado.
1. Stir in lemon juice, olive oil, tomato, garlic, sugar and salt and pepper to taste. Serve immediately as avocados have a tendency to blacken quickly. Serve 4.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
At Last! The Natural PCOS Diet
A Naturopath’s Easy Step-by-Step Guide to Overcome PCOS
by Qualified Australian Naturopath And Hormone Health Expert
Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Tasty Italian with Mexican format - Prosciutto Pepper Quesadillas
Everyday Italian by Jean Pare and Sophia De Luca (Original series), Publisher Company's Coming.
You can view their website at www.companycoming.com
Tasty Italian flavours in a decidedly Mexican format.
This is fusion cuisine at it finest!
Silvered red pepper 1 cup 250mL
Chopped arugula, lightly packed 1/2 cup 125mL
Chopped prosciutto (or deli) ham 1/4 cup 60mL
Grated mozzarella cheese 1 cup 250mL
Flour tortillas (9inch, 23cm diameter) 2 2
Cooking oil 1/2tsp. 2mL
Combine first 3 ingredients in small bowl.
Sprinkle 1/4 cup (60mL) cheese over half of each tortilla. Spoon red pepper mixture over cheese. Sprinkle remaining cheese over top. Fold tortillas in half to cover filling. Press down lightly.
Brush both sides of quesadilla with cooking oil. Heat large frying pan on medium. Add quesadillas. Cook for about 4 minutes until bottom is golden. Turn. Cook for about 2 minutes until bottom is golden and cheese is melted. Cuts into 4 wedges each for a total of 8 wedges.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
At Last! The Natural PCOS Diet
A Naturopath’s Easy Step-by-Step Guide to Overcome PCOS
by Qualified Australian Naturopath And Hormone Health Expert
Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
You can view their website at www.companycoming.com
Tasty Italian flavours in a decidedly Mexican format.
This is fusion cuisine at it finest!
Silvered red pepper 1 cup 250mL
Chopped arugula, lightly packed 1/2 cup 125mL
Chopped prosciutto (or deli) ham 1/4 cup 60mL
Grated mozzarella cheese 1 cup 250mL
Flour tortillas (9inch, 23cm diameter) 2 2
Cooking oil 1/2tsp. 2mL
Combine first 3 ingredients in small bowl.
Sprinkle 1/4 cup (60mL) cheese over half of each tortilla. Spoon red pepper mixture over cheese. Sprinkle remaining cheese over top. Fold tortillas in half to cover filling. Press down lightly.
Brush both sides of quesadilla with cooking oil. Heat large frying pan on medium. Add quesadillas. Cook for about 4 minutes until bottom is golden. Turn. Cook for about 2 minutes until bottom is golden and cheese is melted. Cuts into 4 wedges each for a total of 8 wedges.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
At Last! The Natural PCOS Diet
A Naturopath’s Easy Step-by-Step Guide to Overcome PCOS
by Qualified Australian Naturopath And Hormone Health Expert
Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Wednesday 30 July 2014
Obesity Complication of Chronic Venus Insufficiency
By Kyle J. Norton
Obesity is defined as a medical condition of excess body fat has accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.
How to calculate your BMI indexBMI= weight (kg)/ height (m2)
Chronic venous insufficiency or CVI is defined as a condition of swelling in the veins in the leg due to blood accumulation as result of the veins no longer working effective in pumping oxygen-depleting blood back to the heart.
How Obesity associates with Chronic Venus Insufficiency
1. In the examination of 36 limbs in 23 nonobese individuals and 44 limbs in 22 obese individuals of the study of "Impact of obesity on venous hemodynamics of the lower limbs" by Willenberg T, Schumacher A, Amann-Vesti B, Jacomella V, Thalhammer C, Diehm N, Baumgartner I, Husmann M., posted in PubMed, researchers filed the conclusion that Lower limb venous flow parameters differ significantly between healthy obese and nonobese individuals. These findings support the mechanical role of abdominal adipose tissue potentially leading to elevated risk for both venous thromboembolism and chronic venous insufficiency.
2. According to the study of "Obesity and impaired venous function" by van Rij AM, De Alwis CS, Jiang P, Christie RA, Hill GB, Dutton SJ, Thomson IA., posted in PubMed, researchers found that The CEAP clinical stage of venous disease is more advanced in obese patients than non-obese patients with comparable anatomical patterns of venous incompetence. This may be the result of raised intra-abdominal pressure reported in previous studies, leading to greater reflux, increased vein diameter and venous pressures.
3. In the study of "Clinical presentation and patterns of venous reflux in Thai patients with chronic venous insufficiency (CVI)" by Kanchanabat B, Wongmahisorn Y, Stapanavatr W, Kanchanasuttirak P, Manomaiphiboon A., posted in PubMed, the group found that Thai patients with CVI were relatively young. Visible varicose veins, pain, oedema and inflammation were uncommon and most patients could maintain their usual activities despite advanced venous disease. An association with obesity was not common. Despite a low prevalence of a history of previous DVT, the prevalence of deep vein reflux was high and commonly combined with superficial venous reflux.
4. In the observation of 40,095 individuals from 803 registers of primary care in Poland of the study of "The influence of environmental factors in chronic venous insufficiency" by Jawien A., posted in PubMed, Jawien A. indicated that in the other developed countries was reported. It was more common in women, but female sex was not found to be a strong risk factor. Among the risk factors most closely associated with CVI were age, family history of varicose veins, and constipation, whatever the sex. This is in keeping with findings from recent epidemiologic studies. Obesity and lack of physical activity were strongly associated with CVI in women, more so than in men.
5. According to the study of "[Influence of environmental risk factors on the development of chronic vein insufficiency]" [Article in Polish] by Sudoł-Szopińska I, Błachowiak K, Koziński P., posted in PubMed, researchers wrote that this paper presents basic information on CVI epidemiology, etiopathogenesis and pathophysiology and also reviews the literature on the following CVI risk factors: obesity, lack of physical activity, dietary habits, including constipation, pregnancy, genetic factors as well as prolonged sedentary or upright position during job performance.
6. Etc.
Treatments of Obesity and Chronic Venus Insufficiency
1. According to the study of "In situ hemodynamics of perforating veins in chronic venous insufficiency" by Delis KT, Husmann M, Kalodiki E, Wolfe JH, Nicolaides AN., posted in PubMed, researchers found that In addition to an increase in diameter, perforator incompetence is characterized by significantly higher mean and peak flow velocities, volume flow, and venous volume displaced outward, and a lower flow pulsatility. Differences in early reflux enable a better hemodynamic stratification of incompetent perforators in CVI classes. In the presence of deep reflux, incompetent perforators sustain further hemodynamic impairment. In situ hemodynamics enable quantification of the function of perforators and can be used in the identification of the clinically relevant perforators and the impact of surgery.
2. In the study of "Effect of external valvuloplasty of the deep vein in the treatment of chronic venous insufficiency of the lower extremity" by Wang SM, Hu ZJ, Li SQ, Huang XL, Ye CS., posted in PubMed, researchers concluded that External valvuloplasty of the femoral vein combined with surgical repair of the superficial venous system improved the hemodynamic status of the lower limbs, restored valvular function more effectively, and achieved better outcomes than surgical repair of the superficial venous system alone.
3. Etc.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
At Last! The Natural PCOS Diet
A Naturopath’s Easy Step-by-Step Guide to Overcome PCOS
by Qualified Australian Naturopath And Hormone Health Expert
Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Obesity is defined as a medical condition of excess body fat has accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.
How to calculate your BMI indexBMI= weight (kg)/ height (m2)
Chronic venous insufficiency or CVI is defined as a condition of swelling in the veins in the leg due to blood accumulation as result of the veins no longer working effective in pumping oxygen-depleting blood back to the heart.
How Obesity associates with Chronic Venus Insufficiency
1. In the examination of 36 limbs in 23 nonobese individuals and 44 limbs in 22 obese individuals of the study of "Impact of obesity on venous hemodynamics of the lower limbs" by Willenberg T, Schumacher A, Amann-Vesti B, Jacomella V, Thalhammer C, Diehm N, Baumgartner I, Husmann M., posted in PubMed, researchers filed the conclusion that Lower limb venous flow parameters differ significantly between healthy obese and nonobese individuals. These findings support the mechanical role of abdominal adipose tissue potentially leading to elevated risk for both venous thromboembolism and chronic venous insufficiency.
2. According to the study of "Obesity and impaired venous function" by van Rij AM, De Alwis CS, Jiang P, Christie RA, Hill GB, Dutton SJ, Thomson IA., posted in PubMed, researchers found that The CEAP clinical stage of venous disease is more advanced in obese patients than non-obese patients with comparable anatomical patterns of venous incompetence. This may be the result of raised intra-abdominal pressure reported in previous studies, leading to greater reflux, increased vein diameter and venous pressures.
3. In the study of "Clinical presentation and patterns of venous reflux in Thai patients with chronic venous insufficiency (CVI)" by Kanchanabat B, Wongmahisorn Y, Stapanavatr W, Kanchanasuttirak P, Manomaiphiboon A., posted in PubMed, the group found that Thai patients with CVI were relatively young. Visible varicose veins, pain, oedema and inflammation were uncommon and most patients could maintain their usual activities despite advanced venous disease. An association with obesity was not common. Despite a low prevalence of a history of previous DVT, the prevalence of deep vein reflux was high and commonly combined with superficial venous reflux.
4. In the observation of 40,095 individuals from 803 registers of primary care in Poland of the study of "The influence of environmental factors in chronic venous insufficiency" by Jawien A., posted in PubMed, Jawien A. indicated that in the other developed countries was reported. It was more common in women, but female sex was not found to be a strong risk factor. Among the risk factors most closely associated with CVI were age, family history of varicose veins, and constipation, whatever the sex. This is in keeping with findings from recent epidemiologic studies. Obesity and lack of physical activity were strongly associated with CVI in women, more so than in men.
5. According to the study of "[Influence of environmental risk factors on the development of chronic vein insufficiency]" [Article in Polish] by Sudoł-Szopińska I, Błachowiak K, Koziński P., posted in PubMed, researchers wrote that this paper presents basic information on CVI epidemiology, etiopathogenesis and pathophysiology and also reviews the literature on the following CVI risk factors: obesity, lack of physical activity, dietary habits, including constipation, pregnancy, genetic factors as well as prolonged sedentary or upright position during job performance.
6. Etc.
Treatments of Obesity and Chronic Venus Insufficiency
1. According to the study of "In situ hemodynamics of perforating veins in chronic venous insufficiency" by Delis KT, Husmann M, Kalodiki E, Wolfe JH, Nicolaides AN., posted in PubMed, researchers found that In addition to an increase in diameter, perforator incompetence is characterized by significantly higher mean and peak flow velocities, volume flow, and venous volume displaced outward, and a lower flow pulsatility. Differences in early reflux enable a better hemodynamic stratification of incompetent perforators in CVI classes. In the presence of deep reflux, incompetent perforators sustain further hemodynamic impairment. In situ hemodynamics enable quantification of the function of perforators and can be used in the identification of the clinically relevant perforators and the impact of surgery.
2. In the study of "Effect of external valvuloplasty of the deep vein in the treatment of chronic venous insufficiency of the lower extremity" by Wang SM, Hu ZJ, Li SQ, Huang XL, Ye CS., posted in PubMed, researchers concluded that External valvuloplasty of the femoral vein combined with surgical repair of the superficial venous system improved the hemodynamic status of the lower limbs, restored valvular function more effectively, and achieved better outcomes than surgical repair of the superficial venous system alone.
3. Etc.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
At Last! The Natural PCOS Diet
A Naturopath’s Easy Step-by-Step Guide to Overcome PCOS
by Qualified Australian Naturopath And Hormone Health Expert
Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
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Quesadillas, a perfect recipe for the end of summer
Recipe attributed to 30 minutes vegetarian recipes by Marie-laude Morin, Publisher Robert Rose at www,robertrose.ca
Fresh basil leaves add an explosion of flavor top this quesadillas. in a perfect recipe for the end of summer.
1/4 cup creamy goat cheese 60mL
3 large or small flour tortillas 3
1 zucchini thinly sliced into round 1
1/4 cup chopped onion 60mL
15 basil leaves 15
1/2 cup shredded Cheddar cheese
1. Spread goat cheese on half of each tortilla.
2. In a skillet, heat 1 tsp. (5mL) oil over medium high heat. Gently fry zucchini rounds, turning once until tender.
3. Place zucchini, tomatoes, onion, basil and cheddar cheese on top of goat cheese. Fold tortillas in half.
4. In a skillet heat 1 tsp. (5mL) oil over medium heat. Fry one quesadilla, turning once, for 2 -3 minutes per side until cheese is melted and tortilla is crispy. Repeat with remaining quesadilla, adding more oil between batches as necessary. Cut each quesadilla into 2 wedges.
Serve 4 to 6.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
At Last! The Natural PCOS Diet
A Naturopath’s Easy Step-by-Step Guide to Overcome PCOS
by Qualified Australian Naturopath And Hormone Health Expert
Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Fresh basil leaves add an explosion of flavor top this quesadillas. in a perfect recipe for the end of summer.
1/4 cup creamy goat cheese 60mL
3 large or small flour tortillas 3
1 zucchini thinly sliced into round 1
1/4 cup chopped onion 60mL
15 basil leaves 15
1/2 cup shredded Cheddar cheese
1. Spread goat cheese on half of each tortilla.
2. In a skillet, heat 1 tsp. (5mL) oil over medium high heat. Gently fry zucchini rounds, turning once until tender.
3. Place zucchini, tomatoes, onion, basil and cheddar cheese on top of goat cheese. Fold tortillas in half.
4. In a skillet heat 1 tsp. (5mL) oil over medium heat. Fry one quesadilla, turning once, for 2 -3 minutes per side until cheese is melted and tortilla is crispy. Repeat with remaining quesadilla, adding more oil between batches as necessary. Cut each quesadilla into 2 wedges.
Serve 4 to 6.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
At Last! The Natural PCOS Diet
A Naturopath’s Easy Step-by-Step Guide to Overcome PCOS
by Qualified Australian Naturopath And Hormone Health Expert
Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Italian version of omelettes - Eggplant Frittata
Everyday Italian by Jean Pare and Sophia De Luca (Original series), Publisher Company's Coming.
You can view their website at www.companycoming.com
Frittatas are the Italian version of omelettes - except they aren't folded and they generally finish cooking under a broiler. This version includes plenty of Italian flavours from eggplant, red pepper and seasoning.
Cooking oil 2tsp. 10mL
Finely chopped peeled eggplant 11/2 cups 375 ml
Dried oregano 1/4tsp. 1mL
Large eggs 8 8
Finely chopped roasted red pepper 1/4 cup 60mL
Sliced green onion 2tbsp. 30mL
Garlic powder 1/4tsp. 2mL
Pepper 1/4tsp. 1mL
Heat cooking oil in large non-sticking frying pan on medium. Add eggplant and oregano. Cook for about 4 minutes, stirring occasionally, until eggplant is softened
Whisk remaining 6 ingredients in medium bowl. Pour over eggplant mixture. Reduce heat to medium-low, covered, for about 8 minutes until bottom is golden and top is almost set. Broil on centre rack oven for about 3 minutes until set. Cut into 6 wedges.
Tip: when baking or broiling food in a frying pan with a handle that isn't ovenproof. Wrap the handle in foil and keep it to the front of the oven, away from the element.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
At Last! The Natural PCOS Diet
A Naturopath’s Easy Step-by-Step Guide to Overcome PCOS
by Qualified Australian Naturopath And Hormone Health Expert
Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
You can view their website at www.companycoming.com
Frittatas are the Italian version of omelettes - except they aren't folded and they generally finish cooking under a broiler. This version includes plenty of Italian flavours from eggplant, red pepper and seasoning.
Cooking oil 2tsp. 10mL
Finely chopped peeled eggplant 11/2 cups 375 ml
Dried oregano 1/4tsp. 1mL
Large eggs 8 8
Finely chopped roasted red pepper 1/4 cup 60mL
Sliced green onion 2tbsp. 30mL
Garlic powder 1/4tsp. 2mL
Pepper 1/4tsp. 1mL
Heat cooking oil in large non-sticking frying pan on medium. Add eggplant and oregano. Cook for about 4 minutes, stirring occasionally, until eggplant is softened
Whisk remaining 6 ingredients in medium bowl. Pour over eggplant mixture. Reduce heat to medium-low, covered, for about 8 minutes until bottom is golden and top is almost set. Broil on centre rack oven for about 3 minutes until set. Cut into 6 wedges.
Tip: when baking or broiling food in a frying pan with a handle that isn't ovenproof. Wrap the handle in foil and keep it to the front of the oven, away from the element.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
At Last! The Natural PCOS Diet
A Naturopath’s Easy Step-by-Step Guide to Overcome PCOS
by Qualified Australian Naturopath And Hormone Health Expert
Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
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