Kyle J. Norton
Cancer is a class of diseases associated with cell growth disorderly and uncontrollably in the tissue of a specific organ. Over time cancer can become progressively worse and damage other healthy tissues.
Head and neck cancer is a class of cancer including the mouth, nose, throat, larynx, sinuses, or salivary glands.
Most cases of head and neck cancer start in the cells of the inner lining of the affected tissue. Patients with head and neck cancer at the very early stage are asymptomatic due to the very small size of the tumor. However, at the later stage, the cancer cell can travel a distance away from the original site to infect other healthy tissues and organs, leading to secondary metastasis.
The exact causes of head and neck cancer are not identified. However, researchers found that excessive alcohol intake, smoking, infection by the HPV virus, poor oral health, race, long-term exposure to wood dust are prevalent factors associated with an increased risk of head and neck cancer.
Dr. Shu-Chun Chuang in the investigation of the risk of diet on head and neck cancer (HNC) wrote, "An inverse association was observed for higher frequency intake of fruit (4th vs. 1st quartile OR=0.52, 95% CI=0.43–0.62, ptrend<0.01) and vegetables (OR=0.66, 95% CI=0.49–0.90, ptrend=0.01). Intake of red meat (OR=1.40, 95% CI=1.13–1.74, ptrend=0.13) and processed meat (OR=1.37, 95% CI=1.14–1.65, ptrend<0.01) were positively associated with HNC risk. Higher dietary pattern scores, reflecting high fruit/vegetable and low red meat intake, were associated with reduced HNC risk (per score increment OR=0.90, 95% CI=0.84–0.97)". wrote, "
In other words, a diet rich with fruits and vegetables and low red meat intake reduces the risk of HNC, whereas, a diet rich with red meat and processed meat is associated with a higher risk of the disease.
The onion is a plant in the genus Allium, belonging to the family Alliaceae, which a close relation of garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.
Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild or sweet.
In the urgency to find a potential compound for the treatment of head and neck cancer, researchers investigated the potentially favorable role of garlic and onion within the International Head and Neck Cancer Epidemiology (INHANCE) Consortium.
By analyzing the pooled individual-level data from eight case-control studies, including 4590 cases and 7082 controls, researchers found that at the 95% confidence intervals (CIs) for associations between garlic and onion intakes and HNC
* The ORs of 0.95 were associated with participants with no or low garlic use, and 0.74 for high garlic use participants.
* Increasing onion intake OR was 0.91 ( for >1 to ≤3 portions per week) and 0.83 ( for >3 portions per week) compared to <1 portion per week.
* Furthermore, higher onion intake showed a significant inverse association with laryngeal cancer risk (OR = 0.69; 95% CI 0.54-0.88).
In other words, the risk of head and neck cancer are decreased proportionally with the amount intake of onion daily and weekly, particularly in laryngeal cancer.
Based on the findings, researchers wrote, "The results of this pooled analysis support a possible moderate inverse association between... onion intake and HNC risk".
Taken together, onion may be considered a remedy for the prevention and treatment of head and neck cancer, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Relation of allium vegetables intake with head and neck cancers: evidence from the INHANCE consortium by Galeone C1, Turati F1, Zhang ZF2, Guercio V3, Tavani A1, Serraino D4, Brennan P5, Fabianova E6, Lissowska J7, Mates D8, Rudnai P9, Shangina O10, Szeszenia-Dabrowska N11, Vaughan TL12, Kelsey K13, McClean M14, Levi F15, Hayes RB16, Purdue MP17, Bosetti C1, Brenner H18,19, Pelucchi C1, Lee YC20, Hashibe M21, Boffetta P22, La Vecchia C. (PubMed)
(2) Diet and the Risk of Head and Neck Cancer: A Pooled Analysis in the INHANCE Consortium by Shu-Chun Chuang,1,2 Mazda Jenab,2 Julia E. Heck,3 Cristina Bosetti,4 Renato Talamini,5Keitaro Matsuo,6 Xavier Castellsague,7 Silvia Franceschi,2 Rolando Herrero,8Deborah M. Winn,9 Carlo La Vecchia,4,10 Hal Morgenstern,11 Zuo-Feng Zhang,3 Fabio Levi,12Luigino Dal Maso,5 Karl Kelsey,13 Michael D. McClean,14 Thomas Vaughan,15Philip Lazarus,16 Joshua Muscat,16 Heribert Ramroth,17 Chu Chen,15 Stephen M. Schwartz,15Jose Eluf-Neto,18 Richard B. Hayes,19 Mark Purdue,9 Stefania Boccia,20,21 Gabriella Cadoni,22David Zaridze,23 Sergio Koifman,24 Maria Paula Curado,2 Wolfgang Ahrens,25Simone Benhamou,26 Elena Matos,27 Pagona Lagiou,28 Neonilla Szeszenia-Dabrowska,29Andrew F. Olshan,30 Leticia Fernandez,31 Ana Menezes,32 Antonio Agudo,33Alexander W. Daudt,34 Franco Merletti,35 Gary J. Macfarlane,36 Kristina Kjaerheim,37Dana Mates,38 Ivana Holcatova,39 Stimson Schantz,40 Guo-Pei Yu,40 Lorenzo Simonato,41Hermann Brenner,42 Heiko Mueller,42 David I. Conway,43 Peter Thomson,44Eleonora Fabianova,45 Ariana Znaor,46 Peter Rudnai,47 Claire M. Healy,48 Gilles Ferro,2Paul Brennan,2 Paolo Boffetta,49,50 and Mia Hashibe. (PMC)
Thursday, 26 October 2023
#Herbal #Turmeric and Its #Curcumin in the Promotiopn of Reproductive System Functioning, Researchers Find
Kyle J. Norton
The reproductive system is a system of sex organs with a function to produce offspring.
In males, the reproductive system consists of the testes, where sperm is produced, and the penis.
In females, the structures of the reproductive system include the clitoris, labia minora, labia majora, and Bartholin's glands and internal structures include the vagina, uterus, and ovaries.
The most common cause of reproductive organ disease is an infection. In females, reproductive tract infections can affect the upper reproductive tract (fallopian tubes, ovaries, and uterus) and the lower reproductive tract (vagina, cervix, and vulva).
In males, most cases of infection are found on the penis, testicles, urethra, or the vas deferens.
Some cases of reproductive diseases such as cancer have been found to affect reproductive functioning, leading to infertility.
Fertility is a natural capability to produce offspring. Infertility is a condition in which the couple fails to conceive after 12 months of unprotected sexual intercourse or the female cannot carry the pregnancy to full term.
According to the statistics, over 5 million couples in the U. S. and many times more in the world, because of unawareness of treatments, only 10% seek help from a professional specialist.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
With an aim to find a natural compound for the improvement of reproductive functioning, researchers
examined the effects of Curcuma longa and curcumin (CUR) on reproductive systems, by searching the detailed literature survey concentrated on the protective effects of C. longa and curcumin on the activity of the reproductive organs.
According to the results of the searching from PubMed, Web of Science, Google Scholar, Scopus, and Iran- Medex, injection of C. longa and curcumin decreased the risk of cancer and other malignant diseases in the reproductive system by inhibiting the production of the proinflammatory cytokines and promoting the proteins associated with anti-apoptosis in the cells of the reproductive system.
Furthermore, C. longa and curcumin exerted a protective effect on the activity of the reproductive organs through their antioxidant effects in normal cells.
Moreover, C. longa and curcumin also exhibited different reproductive effects depending on the doses and the type of cells.
In order to discover more information about CUR reproductive activity, researchers examined the effect of on testis and testosterone, follicle-stimulating hormone (FSH), and luteinizing hormone (LH) in rats with establishing chronic variable stress (CVS).
A total of 21 adult male Sprague-Dawley rats included in the study were divided into three groups: 1) control, 2) CVS and 3) CVS+ CUR (100 mg/kg/day dissolved in 0.5 mL of olive oil). All of the animals in control, CVS, and CVS+CUR groups were sacrificed after 15 days.
Injection CUR showed a significant effect in protecting the reproductive functioning by inhibiting the change of normal range testosterone, follicle-stimulating hormone (FSH) and luteinizing hormone (LH) serum levels and seminiferous tubule apoptotic cells in the CVS group compared to the control.
Based on the results, Dr. the lead scientist said, "Our findings propose that curcumin might have curative potential on the reproductive system function and its impairment. It's regulated by stress and reproductive-related hormones".
Taken together, turmeric and its bioactive compound may be considered remedies for the treatment of reproductive dysfunction, pending the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The effects of Curcuma longa and curcumin on reproductive systems by Mohebbati R1, Anaeigoudari A1, Khazdair MR. (PubMed)
(2) Protective effects of curcumin co-treatment in rats with establishing chronic variable stress on testis and reproductive hormones by Mohamadpour M1,2, Noorafshan A1,2, Karbalay-Doust S1,2, Talaei-Khozani T2, Aliabadi E. (PubMed)
The reproductive system is a system of sex organs with a function to produce offspring.
In males, the reproductive system consists of the testes, where sperm is produced, and the penis.
In females, the structures of the reproductive system include the clitoris, labia minora, labia majora, and Bartholin's glands and internal structures include the vagina, uterus, and ovaries.
The most common cause of reproductive organ disease is an infection. In females, reproductive tract infections can affect the upper reproductive tract (fallopian tubes, ovaries, and uterus) and the lower reproductive tract (vagina, cervix, and vulva).
In males, most cases of infection are found on the penis, testicles, urethra, or the vas deferens.
Some cases of reproductive diseases such as cancer have been found to affect reproductive functioning, leading to infertility.
Fertility is a natural capability to produce offspring. Infertility is a condition in which the couple fails to conceive after 12 months of unprotected sexual intercourse or the female cannot carry the pregnancy to full term.
According to the statistics, over 5 million couples in the U. S. and many times more in the world, because of unawareness of treatments, only 10% seek help from a professional specialist.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
With an aim to find a natural compound for the improvement of reproductive functioning, researchers
examined the effects of Curcuma longa and curcumin (CUR) on reproductive systems, by searching the detailed literature survey concentrated on the protective effects of C. longa and curcumin on the activity of the reproductive organs.
According to the results of the searching from PubMed, Web of Science, Google Scholar, Scopus, and Iran- Medex, injection of C. longa and curcumin decreased the risk of cancer and other malignant diseases in the reproductive system by inhibiting the production of the proinflammatory cytokines and promoting the proteins associated with anti-apoptosis in the cells of the reproductive system.
Furthermore, C. longa and curcumin exerted a protective effect on the activity of the reproductive organs through their antioxidant effects in normal cells.
Moreover, C. longa and curcumin also exhibited different reproductive effects depending on the doses and the type of cells.
In order to discover more information about CUR reproductive activity, researchers examined the effect of on testis and testosterone, follicle-stimulating hormone (FSH), and luteinizing hormone (LH) in rats with establishing chronic variable stress (CVS).
A total of 21 adult male Sprague-Dawley rats included in the study were divided into three groups: 1) control, 2) CVS and 3) CVS+ CUR (100 mg/kg/day dissolved in 0.5 mL of olive oil). All of the animals in control, CVS, and CVS+CUR groups were sacrificed after 15 days.
Injection CUR showed a significant effect in protecting the reproductive functioning by inhibiting the change of normal range testosterone, follicle-stimulating hormone (FSH) and luteinizing hormone (LH) serum levels and seminiferous tubule apoptotic cells in the CVS group compared to the control.
Based on the results, Dr. the lead scientist said, "Our findings propose that curcumin might have curative potential on the reproductive system function and its impairment. It's regulated by stress and reproductive-related hormones".
Taken together, turmeric and its bioactive compound may be considered remedies for the treatment of reproductive dysfunction, pending the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The effects of Curcuma longa and curcumin on reproductive systems by Mohebbati R1, Anaeigoudari A1, Khazdair MR. (PubMed)
(2) Protective effects of curcumin co-treatment in rats with establishing chronic variable stress on testis and reproductive hormones by Mohamadpour M1,2, Noorafshan A1,2, Karbalay-Doust S1,2, Talaei-Khozani T2, Aliabadi E. (PubMed)
#Phytochemical 3,3'-Diindolylmethane Exerts a Strong Effect on #Cellular and Molecular Levels Associated with a Reduced Risk of Chronic Diseases
Kyle J. Norton
Scientists may have found a bioactive ingredient for the treatment of chronic diseases, with no side effects, according to studies.
Chronic diseases are a group of medical conditions most commonly associated with aging, including
arthritis, cardiovascular diseases such as heart attacks and stroke, cancer, diabetes, epilepsy and seizures, and obesity.
The exact causes of chronic diseases are not identified. Aging, unhealthy lifestyle such as excessive alcohol drinking smoking, poor diet, lack of physical activity are the most common risk factors associated with the onset of the disease.
According to the joint study led by Fordham University, chronic diseases are among the most prevalent and costly health conditions in the US, affecting over 133 million US population as many of them suffer from at least one chronic disease and the number is growing at a rapid rate.
Some chronic diseases such as cancer have been found to be the leading causes of hospitalization, long-term disability, reduced quality of life, and death.
According to the Centers for Disease Control, chronic diseases also are the major driver of healthcare costs accounted for nearly 75 percent of aggregate healthcare spending, and increased absenteeism impacts workforce patterns.
Each chronic patient has cost the health care spending $5300 annually.
Believe it or not, chronic diseases in the US, chronic diseases are responsible for 7 out of 10 deaths yearly. In other words, chronic diseases kill more than 1.7 million Americans each year.
Some researchers suggested by changing unhealthy lifestyle patterns, chronic diseases may be preventable.
Dr. Walter C. Willett, the lead scientist in the concern about the risk chronic disease in poor lifestyle individuals wrote, "Several lines of evidence indicate that realistic modifications of diet and lifestyle can prevent most CAD, stroke, diabetes, colon cancer, and smoking-related cancers".
And, "Among U.S. adults, more than 90 percent of type 2 diabetes, 80 percent of CAD, 70 percent of stroke, and 70 percent of colon cancer are potentially preventable by a combination of nonsmoking, avoidance of overweight, moderate physical activity, healthy diet, and moderate alcohol consumption".
Researchers on finding a natural ingredient for the treatment of chronic diseases analyzed 3,3'-diindolylmethane (DIM) several biological activities on cellular and molecular levels against chronic diseases, including cancer.
DIM enhanced the function of the drug-metabolizing enzyme by blocking activity involved in the promotion of cancer expression.
DIM affects multiple signaling pathways and target molecules that controls cell division, apoptosis, or angiogenesis deregulated in cancer cells.
DIM also prevented the development of hormone-dependent cancers.
Injection of DIM also was found to inhibit the onset of cardiovascular disease, obesity, and diabetes reduction through its antioxidant property in reducing oxidative stress caused by overexpression of free radicals.
Dr. Licznerska B, the lead scientist after taking into account other factors wrote in the final report, "the current experimental data on the I3C and DIM activity and the results of clinical studies indicating their role in the prevention of chronic diseases".
Taken altogether, 3,3'-Diindolylmethane derived from the digestion of indole-3-carbinol may be considered a supplement for the prevention and treatment of chronic diseases, pending to the confirmation of the larger sample size and multicenter human study.
Intake of 3,3'-diindolylmethane in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Indole-3-Carbinol and Its Role in Chronic Diseases by Licznerska B1, Baer-Dubowska W. (PubMed)
(2) An Empirical Study of Chronic Diseases in the United States: A Visual Analytics Approach to Public Health by Wullianallur Raghupathi1 and Viju Raghupathi. (PubMed)
(3) Prevention of Chronic Disease by Means of Diet and Lifestyle Changes by Walter C. Willett, Jeffrey P. Koplan, Rachel Nugent, Courtenay Dusenbury, Pekka Puska, and Thomas A. Gaziano. (PubMed)
Scientists may have found a bioactive ingredient for the treatment of chronic diseases, with no side effects, according to studies.
Chronic diseases are a group of medical conditions most commonly associated with aging, including
arthritis, cardiovascular diseases such as heart attacks and stroke, cancer, diabetes, epilepsy and seizures, and obesity.
The exact causes of chronic diseases are not identified. Aging, unhealthy lifestyle such as excessive alcohol drinking smoking, poor diet, lack of physical activity are the most common risk factors associated with the onset of the disease.
According to the joint study led by Fordham University, chronic diseases are among the most prevalent and costly health conditions in the US, affecting over 133 million US population as many of them suffer from at least one chronic disease and the number is growing at a rapid rate.
Some chronic diseases such as cancer have been found to be the leading causes of hospitalization, long-term disability, reduced quality of life, and death.
According to the Centers for Disease Control, chronic diseases also are the major driver of healthcare costs accounted for nearly 75 percent of aggregate healthcare spending, and increased absenteeism impacts workforce patterns.
Each chronic patient has cost the health care spending $5300 annually.
Believe it or not, chronic diseases in the US, chronic diseases are responsible for 7 out of 10 deaths yearly. In other words, chronic diseases kill more than 1.7 million Americans each year.
Some researchers suggested by changing unhealthy lifestyle patterns, chronic diseases may be preventable.
Dr. Walter C. Willett, the lead scientist in the concern about the risk chronic disease in poor lifestyle individuals wrote, "Several lines of evidence indicate that realistic modifications of diet and lifestyle can prevent most CAD, stroke, diabetes, colon cancer, and smoking-related cancers".
And, "Among U.S. adults, more than 90 percent of type 2 diabetes, 80 percent of CAD, 70 percent of stroke, and 70 percent of colon cancer are potentially preventable by a combination of nonsmoking, avoidance of overweight, moderate physical activity, healthy diet, and moderate alcohol consumption".
Researchers on finding a natural ingredient for the treatment of chronic diseases analyzed 3,3'-diindolylmethane (DIM) several biological activities on cellular and molecular levels against chronic diseases, including cancer.
DIM enhanced the function of the drug-metabolizing enzyme by blocking activity involved in the promotion of cancer expression.
DIM affects multiple signaling pathways and target molecules that controls cell division, apoptosis, or angiogenesis deregulated in cancer cells.
DIM also prevented the development of hormone-dependent cancers.
Injection of DIM also was found to inhibit the onset of cardiovascular disease, obesity, and diabetes reduction through its antioxidant property in reducing oxidative stress caused by overexpression of free radicals.
Dr. Licznerska B, the lead scientist after taking into account other factors wrote in the final report, "the current experimental data on the I3C and DIM activity and the results of clinical studies indicating their role in the prevention of chronic diseases".
Taken altogether, 3,3'-Diindolylmethane derived from the digestion of indole-3-carbinol may be considered a supplement for the prevention and treatment of chronic diseases, pending to the confirmation of the larger sample size and multicenter human study.
Intake of 3,3'-diindolylmethane in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Indole-3-Carbinol and Its Role in Chronic Diseases by Licznerska B1, Baer-Dubowska W. (PubMed)
(2) An Empirical Study of Chronic Diseases in the United States: A Visual Analytics Approach to Public Health by Wullianallur Raghupathi1 and Viju Raghupathi. (PubMed)
(3) Prevention of Chronic Disease by Means of Diet and Lifestyle Changes by Walter C. Willett, Jeffrey P. Koplan, Rachel Nugent, Courtenay Dusenbury, Pekka Puska, and Thomas A. Gaziano. (PubMed)
#Herbal #Arctostaphylos uva-ursi's Water extract (UW-ext) Processes a Strong Antiinflammatory Activity, Researchers Suggest
Kyle J. Norton
Arctostaphylos uva-ursi is one of the species of Bearberry, in the genus Arctostaphylos, belonging to the family Ericaceae, native to northern North America, Asia, and Europe. The herb has been used in traditional medicine as a diuretic agent and to treat urinary problems, including bladder infections, kidney infections, kidney stones, pelvic pain, etc. Inflammation is a condition of the Immune system's self-protection to remove harmful stimuli, including damaged cells, irritants, and pathogens... from our body.
The Ingredients It contains arbutin, ursolic acid, tannic acid, gallic acid, some essential oil and resin, hydroquinones tannins, phenolic glycosides, and flavonoids.
Water extract (UW-ext) collected from the leaf of Arctostaphylos uva-ursi (L.) Spreng (Bearberry leaf), is found to exhibit anti-inflammatory effects in ear swelling by picryl chloride-induced contact dermatitis (PC-CD) and carrageenin-induced paw edema. arbutin isolated from the leaves of Arctostaphylos uva-ursi (L.) Spreng., when combined with indomethacin on Type IV allergic reaction-induced immuno-inflammation, carrageenin-induced edema, and adjuvant-induced arthritis, found to be effective as arbutin may increase the inhibitory action of indomethacin on PC-CD, SRBC-DTH, carrageenin-induced edema, and adjuvant-induced arthritis, but further investigations are required to understand the mechanism involved. Other studies also indicated that 50% methanolic extract (U-ext), containing arbutin, possesses a therapeutic effect against immuno-inflammation induced by picryl chloride (PC-CD) and also increases the inhibitory effect of prednisolone.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Herbal Therapy http://kylejnorton.blogspot.ca/p/herbal-therapies.html
References
(1) [Pharmacological studies on leaf of Arctostaphylos uva-ursi (L.) Spreng. V. Effect of water extract from Arctostaphylos uva-ursi (L.) Spreng. (bearberry leaf) on the antiallergic and antiinflammatory activities of dexamethasone ointment].[Article in Japanese] by Matsuda H, Nakamura S, Tanaka T, Kubo M.(PubMed)
(2) [Pharmacological studies on leaf of Arctostaphylos uva-ursi (L.) Spreng. III. Combined effect of arbutin and indomethacin on immuno-inflammation].[Article in Japanese] by Matsuda H, Tanaka T, Kubo M.(PubMed)
(3) [Pharmacological studies on leaf of Arctostaphylos uva-ursi (L.) Spreng. I. Combined effect of 50% methanolic extract from Arctostaphylos uva-ursi (L.) Spreng. (bearberry leaf) and prednisolone on immuno-inflammation].[Article in Japanese] by Kubo M, Ito M, Nakata H, Matsuda H.(PubMed)
Arctostaphylos uva-ursi is one of the species of Bearberry, in the genus Arctostaphylos, belonging to the family Ericaceae, native to northern North America, Asia, and Europe. The herb has been used in traditional medicine as a diuretic agent and to treat urinary problems, including bladder infections, kidney infections, kidney stones, pelvic pain, etc. Inflammation is a condition of the Immune system's self-protection to remove harmful stimuli, including damaged cells, irritants, and pathogens... from our body.
The Ingredients It contains arbutin, ursolic acid, tannic acid, gallic acid, some essential oil and resin, hydroquinones tannins, phenolic glycosides, and flavonoids.
Water extract (UW-ext) collected from the leaf of Arctostaphylos uva-ursi (L.) Spreng (Bearberry leaf), is found to exhibit anti-inflammatory effects in ear swelling by picryl chloride-induced contact dermatitis (PC-CD) and carrageenin-induced paw edema. arbutin isolated from the leaves of Arctostaphylos uva-ursi (L.) Spreng., when combined with indomethacin on Type IV allergic reaction-induced immuno-inflammation, carrageenin-induced edema, and adjuvant-induced arthritis, found to be effective as arbutin may increase the inhibitory action of indomethacin on PC-CD, SRBC-DTH, carrageenin-induced edema, and adjuvant-induced arthritis, but further investigations are required to understand the mechanism involved. Other studies also indicated that 50% methanolic extract (U-ext), containing arbutin, possesses a therapeutic effect against immuno-inflammation induced by picryl chloride (PC-CD) and also increases the inhibitory effect of prednisolone.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Herbal Therapy http://kylejnorton.blogspot.ca/p/herbal-therapies.html
References
(1) [Pharmacological studies on leaf of Arctostaphylos uva-ursi (L.) Spreng. V. Effect of water extract from Arctostaphylos uva-ursi (L.) Spreng. (bearberry leaf) on the antiallergic and antiinflammatory activities of dexamethasone ointment].[Article in Japanese] by Matsuda H, Nakamura S, Tanaka T, Kubo M.(PubMed)
(2) [Pharmacological studies on leaf of Arctostaphylos uva-ursi (L.) Spreng. III. Combined effect of arbutin and indomethacin on immuno-inflammation].[Article in Japanese] by Matsuda H, Tanaka T, Kubo M.(PubMed)
(3) [Pharmacological studies on leaf of Arctostaphylos uva-ursi (L.) Spreng. I. Combined effect of 50% methanolic extract from Arctostaphylos uva-ursi (L.) Spreng. (bearberry leaf) and prednisolone on immuno-inflammation].[Article in Japanese] by Kubo M, Ito M, Nakata H, Matsuda H.(PubMed)
#Healthy #Tomatoes' Lycopene Inhibits Primary Lung Cancer Induced by Tobacco Carcinogen 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-Butanone (NNK)
Kyle J. Norton
Primary lung cancer is a medical and chronic condition characterized by irregular cell growth in the tissues of the lung.
The lungs are a pair of spongy, air-filled organs located on either side of the chest, with the function of inspiration that takes oxygen from incoming air to the blood and releases carbon dioxide.
In other words, the lung exchanges carbon dioxide from the blood to oxygen.
Furthermore, the lung also filters out a small blood clot, balancing the Ph levels in the body, protecting the body from infection as well as speech.
According to the statistics, in the US, approximately 228,000 people in the US will be diagnosed with lung cancer in 2019 or 1 in 16 people in the US will be diagnosed with lung cancer in their lifetime.
About 60% to 65% of all new lung cancer diagnoses are among people who have never smoked or are former smokers.
Most cases of lung cancer at the early stage are asymptomatic due to the very small size of the tumor. However, at the later stage, the oversize of the tumor not only reduces the lung function but also presses on the nearby nerve cells and blood vessels, leading to symptoms of lung cancer, accompanied by general symptoms shared by other types of cancer.
The most common symptoms of lung cancer include a persistent cough, cough-up blood with rust-colored sputum (spit or phlegm) due to the oversized tumor that has pressed on nearby blood vessels, chest pain due to the oversize tumor that has pressed on the nerve cells and shortness of breath. Feeling tired or weak.
The other lung, adrenal gland, bones, brain, and liver are most common in primary lung cancer metastasis.
Some researchers suggested lung cancer in the US may be correlated to the rise of obesity.
Dr. Khemayanto Hidayat, the lead scientist said, "Several meta-analyses of observational studies have been performed to examine the association between general obesity, as measured by body mass index (BMI), and lung cancer. These meta-analyses suggest an inverse relationship between high BMI and this cancer. In contrast to general obesity, abdominal obesity appears to play a role in the development of lung cancer".
And, "greater WC was associated with increased lung cancer risk among never smokers (RR 1.11; 95% CI 1.00, 1.23), former smokers (RR 1.12; 95% CI 1.03, 1.22) and current smokers (RR 1.16; 95% CI 1.08, 1.25). The summary RRs for the highest versus lowest categories of WC and WHR were 1.32 (95% CI 1.13, 1.54; I2 = 18.2%, p-heterogeneity = 0.281) and 1.10 (95% CI 1.00, 1.23; I2 = 24.2%, p-heterogeneity = 0.211), respectively".
Tomato is a red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.
In finding a natural compound for the treatment of lung cancer, researchers in the cancer team at Tufts University investigated the effects of tomato's lycopene against tobacco carcinogen 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induced lesions in both lungs in an animal model.
The study included elected male ferrets (6 groups, n = 8-10) who were treated either with NNK (50 mg/kg BW, i.p., once a month for four consecutive months) or saline with or without dietary lycopene supplementation (2.2 and 6.6 mg/kg BW/day, respectively) for 26 weeks.
Before the treatment of lycopene, NNK-exposure ferrets showed higher incidences of lung tumors, HCC, and steatohepatitis, and elevations in bilirubin and AST levels.
Lycopene supplementation treatment at two doses prevented NNK-induced lung toxicity and inflammation. The expression of levels of CYP2E1 in the liver associated with the metabolism of xenobiotics in the liver was also inhibited by the injection of lycopene.
In other words, lycopene prevented the NNK in the induction of lung and liver damage in the tested animals.
Based on the findings, researchers said, "The present study provided strong experimental evidence that the tobacco carcinogen NNK can induce both HCC and steatohepatitis in the ferrets and can be a useful model for studying tobacco carcinogen-associated NAFLD and liver cancer".
Furthermore, in a mouse model associated with colon cancer metastatic to the lungs, Dr. Chattopadhyay A, the lead scientist wrote, "adding 0.06% of Tg6F, but not a control tomato concentrate (EV), to standard mouse chow reduced tumor-associated neutrophils by 94 ± 1.1%, and reduced tumor burden by two-thirds".
Taken together, cooked tomatoes processed with abundantly bioactive compound lycopene may be considered supplements for the prevention and treatment of complications caused by oxidative stress, pending the confirmation of the larger sample size and multicenter human study.
Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Efficacy of tomato concentrates in mouse models of dyslipidemia and cancer by Chattopadhyay A1, Grijalva V1, Hough G1, Su F2, Mukherjee P1, Farias-Eisner R2, Anantharamaiah GM3, Faull KF4, Hwang LH4, Navab M1, Fogelman AM1, Reddy ST. (PubMed)
(2) Tobacco carcinogen induces both lung cancer and non-alcoholic steatohepatitis and hepatocellular carcinomas in ferrets which can be attenuated by lycopene supplementation by Aizawa K1,2, Liu C1, Tang S1, Veeramachaneni S1, Hu KQ1, Smith DE3, Wang XD. (PubMed)
(3) Abdominal Obesity and Lung Cancer Risk: Systematic Review and Meta-Analysis of Prospective Studies by Khemayanto Hidayat,1 Xuan Du,1 Guochong Chen,2 Minhua Shi,3 and Bimin Shi. (PMC)
Primary lung cancer is a medical and chronic condition characterized by irregular cell growth in the tissues of the lung.
The lungs are a pair of spongy, air-filled organs located on either side of the chest, with the function of inspiration that takes oxygen from incoming air to the blood and releases carbon dioxide.
In other words, the lung exchanges carbon dioxide from the blood to oxygen.
Furthermore, the lung also filters out a small blood clot, balancing the Ph levels in the body, protecting the body from infection as well as speech.
According to the statistics, in the US, approximately 228,000 people in the US will be diagnosed with lung cancer in 2019 or 1 in 16 people in the US will be diagnosed with lung cancer in their lifetime.
About 60% to 65% of all new lung cancer diagnoses are among people who have never smoked or are former smokers.
Most cases of lung cancer at the early stage are asymptomatic due to the very small size of the tumor. However, at the later stage, the oversize of the tumor not only reduces the lung function but also presses on the nearby nerve cells and blood vessels, leading to symptoms of lung cancer, accompanied by general symptoms shared by other types of cancer.
The most common symptoms of lung cancer include a persistent cough, cough-up blood with rust-colored sputum (spit or phlegm) due to the oversized tumor that has pressed on nearby blood vessels, chest pain due to the oversize tumor that has pressed on the nerve cells and shortness of breath. Feeling tired or weak.
The other lung, adrenal gland, bones, brain, and liver are most common in primary lung cancer metastasis.
Some researchers suggested lung cancer in the US may be correlated to the rise of obesity.
Dr. Khemayanto Hidayat, the lead scientist said, "Several meta-analyses of observational studies have been performed to examine the association between general obesity, as measured by body mass index (BMI), and lung cancer. These meta-analyses suggest an inverse relationship between high BMI and this cancer. In contrast to general obesity, abdominal obesity appears to play a role in the development of lung cancer".
And, "greater WC was associated with increased lung cancer risk among never smokers (RR 1.11; 95% CI 1.00, 1.23), former smokers (RR 1.12; 95% CI 1.03, 1.22) and current smokers (RR 1.16; 95% CI 1.08, 1.25). The summary RRs for the highest versus lowest categories of WC and WHR were 1.32 (95% CI 1.13, 1.54; I2 = 18.2%, p-heterogeneity = 0.281) and 1.10 (95% CI 1.00, 1.23; I2 = 24.2%, p-heterogeneity = 0.211), respectively".
Tomato is a red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.
In finding a natural compound for the treatment of lung cancer, researchers in the cancer team at Tufts University investigated the effects of tomato's lycopene against tobacco carcinogen 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induced lesions in both lungs in an animal model.
The study included elected male ferrets (6 groups, n = 8-10) who were treated either with NNK (50 mg/kg BW, i.p., once a month for four consecutive months) or saline with or without dietary lycopene supplementation (2.2 and 6.6 mg/kg BW/day, respectively) for 26 weeks.
Before the treatment of lycopene, NNK-exposure ferrets showed higher incidences of lung tumors, HCC, and steatohepatitis, and elevations in bilirubin and AST levels.
Lycopene supplementation treatment at two doses prevented NNK-induced lung toxicity and inflammation. The expression of levels of CYP2E1 in the liver associated with the metabolism of xenobiotics in the liver was also inhibited by the injection of lycopene.
In other words, lycopene prevented the NNK in the induction of lung and liver damage in the tested animals.
Based on the findings, researchers said, "The present study provided strong experimental evidence that the tobacco carcinogen NNK can induce both HCC and steatohepatitis in the ferrets and can be a useful model for studying tobacco carcinogen-associated NAFLD and liver cancer".
Furthermore, in a mouse model associated with colon cancer metastatic to the lungs, Dr. Chattopadhyay A, the lead scientist wrote, "adding 0.06% of Tg6F, but not a control tomato concentrate (EV), to standard mouse chow reduced tumor-associated neutrophils by 94 ± 1.1%, and reduced tumor burden by two-thirds".
Taken together, cooked tomatoes processed with abundantly bioactive compound lycopene may be considered supplements for the prevention and treatment of complications caused by oxidative stress, pending the confirmation of the larger sample size and multicenter human study.
Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Efficacy of tomato concentrates in mouse models of dyslipidemia and cancer by Chattopadhyay A1, Grijalva V1, Hough G1, Su F2, Mukherjee P1, Farias-Eisner R2, Anantharamaiah GM3, Faull KF4, Hwang LH4, Navab M1, Fogelman AM1, Reddy ST. (PubMed)
(2) Tobacco carcinogen induces both lung cancer and non-alcoholic steatohepatitis and hepatocellular carcinomas in ferrets which can be attenuated by lycopene supplementation by Aizawa K1,2, Liu C1, Tang S1, Veeramachaneni S1, Hu KQ1, Smith DE3, Wang XD. (PubMed)
(3) Abdominal Obesity and Lung Cancer Risk: Systematic Review and Meta-Analysis of Prospective Studies by Khemayanto Hidayat,1 Xuan Du,1 Guochong Chen,2 Minhua Shi,3 and Bimin Shi. (PMC)
#Herbal #Bilberry's #Anthocyanoside Protects the Stomach Against HCl/Ethanol-Induced Gastric Ulcer and Chronic Gastric Ulcer, Studies Say
Kyle J. Norton
Gastric, stomach ulcer is an oval sore found on the lining of the stomach.
A gastric ulcer is one of the most common types of peptic ulcer disease which affects both the stomach and small intestines.
According to epidemiological studies, gastric ulcer is caused either by the infection of the bacterium Helicobacter pylori (H. pylori) or long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin.
The most common symptoms are a burning sensation or pain in the stomach. Most patients with gastric ulcers have pain that intensifies on an empty stomach, depending on the severity of the condition.
Some patients with gastric ulcers also experience persistent dull pain in the stomach, unintended weight loss, nausea or vomiting, and bloating and acid reflux.
If you have some of the aforementioned symptoms, please check with your doctor to rule out the possibility of a gastric ulcer.
Conventionally, most cases of gastric ulcer can be treated successfully depending on the cause, including medicine or surgery if the medicine fails.
Out of many risk factors that cause a gastric ulcer, some researchers suggested there is a correlation between obesity and gastritis as well as gastric ulcers.
Dr. Nadia B. Pietrzykowska said, "Excess body weight has been linked to various abdominal ailments. These may include abdominal pain, bloating, vomiting, heartburn, diarrhea or constipation".
And, "Scientific studies are also increasingly reporting a correlation between obesity and gastritis as well as gastric ulcers. A recent, large study that specifically focused on analyzing gastric and duodenal ulcers confirmed that excess weight predisposed individuals to gastric ulcers when compared to their normal-weight counterparts".
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant berry has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, psoriasis, diabetes, etc.
In the testing of the effect of Vaccinium myrtillus L. anthocyanoside (VMA) used as a folk medicine to treat diseases related to gastric ulcers in northern Europe, researchers investigated the protective effects of VMA on gastric mucosal damage in a murine gastric ulcer model.
During the experiment, oral administration of VMA (10, 30, and 100 mg/kg) significantly protected gastric mucosa against HCl/ethanol-induced gastric ulcers.
VMA protects the stomach by inhibiting lipid peroxide levels in a concentration-dependent manner and exhibiting high scavenging activity against the superoxide anion radical (·O(2) (-) ) and the hydroxyl radical (·OH).
The antioxidant activity in VMA was found to be attributed to the presence of anthocyanidins and delphinidin.
Based on the findings, Dr. Ogawa K, the lead scientist said, "These findings indicate that the protective effects of VMA on HCl/ethanol-induced gastric mucosal injury may be partially due to the antiperoxidative effects of anthocyanidins".
In order to provide more information about VMA gastric protective effects, researchers examined the antiulcer effects of 3,5,7-trihydroxy-2-(3,4-dihydroxyphenyl)-1-benzopyrylium chloride (IdB 1027,
an anthocyanidin from Vaccinium myrtillus) in various experimental models.
Orally, IdB 1027 inhibited all parameters associated with the onset of gastric ulcerations including anti-inflammatory drugs, ethanol, reserpine, histamine, and duodenal ulceration induced by mercaptamine.
Furthermore, IdB 1027 also protects the stomach against chronic gastric ulcers induced by acetic acid.
Moreover, IdB 1027 in the rat model did not affect gastric secretion in pylorus-ligated rats and increased gastric mucus in normal animals both in the absence and in the presence of indomethacin treatment.
In other words, IdB 1027 possessed a promising antiulcer activity, probably by potentiating the defensive barriers of the gastrointestinal mucosa.
Taken together, bilberry may be considered a functional remedy for the prevention and treatment of gastric ulcers, pending to the validation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) The protective effect and action mechanism of Vaccinium myrtillus L. on gastric ulcer in mice by Ogawa K1, Oyagi A, Tanaka J, Kobayashi S, Hara H. (PubMed)
(2) Antiulcer activity of an anthocyanidin from Vaccinium myrtillus by Magistretti MJ1, Conti M, Cristoni A. (PubMed)
(3) Obesity and Gastric Ulcers by Dr. Nadia B. Pietrzykowska. (OMC community)
Gastric, stomach ulcer is an oval sore found on the lining of the stomach.
A gastric ulcer is one of the most common types of peptic ulcer disease which affects both the stomach and small intestines.
According to epidemiological studies, gastric ulcer is caused either by the infection of the bacterium Helicobacter pylori (H. pylori) or long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin.
The most common symptoms are a burning sensation or pain in the stomach. Most patients with gastric ulcers have pain that intensifies on an empty stomach, depending on the severity of the condition.
Some patients with gastric ulcers also experience persistent dull pain in the stomach, unintended weight loss, nausea or vomiting, and bloating and acid reflux.
If you have some of the aforementioned symptoms, please check with your doctor to rule out the possibility of a gastric ulcer.
Conventionally, most cases of gastric ulcer can be treated successfully depending on the cause, including medicine or surgery if the medicine fails.
Out of many risk factors that cause a gastric ulcer, some researchers suggested there is a correlation between obesity and gastritis as well as gastric ulcers.
Dr. Nadia B. Pietrzykowska said, "Excess body weight has been linked to various abdominal ailments. These may include abdominal pain, bloating, vomiting, heartburn, diarrhea or constipation".
And, "Scientific studies are also increasingly reporting a correlation between obesity and gastritis as well as gastric ulcers. A recent, large study that specifically focused on analyzing gastric and duodenal ulcers confirmed that excess weight predisposed individuals to gastric ulcers when compared to their normal-weight counterparts".
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant berry has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, psoriasis, diabetes, etc.
In the testing of the effect of Vaccinium myrtillus L. anthocyanoside (VMA) used as a folk medicine to treat diseases related to gastric ulcers in northern Europe, researchers investigated the protective effects of VMA on gastric mucosal damage in a murine gastric ulcer model.
During the experiment, oral administration of VMA (10, 30, and 100 mg/kg) significantly protected gastric mucosa against HCl/ethanol-induced gastric ulcers.
VMA protects the stomach by inhibiting lipid peroxide levels in a concentration-dependent manner and exhibiting high scavenging activity against the superoxide anion radical (·O(2) (-) ) and the hydroxyl radical (·OH).
The antioxidant activity in VMA was found to be attributed to the presence of anthocyanidins and delphinidin.
Based on the findings, Dr. Ogawa K, the lead scientist said, "These findings indicate that the protective effects of VMA on HCl/ethanol-induced gastric mucosal injury may be partially due to the antiperoxidative effects of anthocyanidins".
In order to provide more information about VMA gastric protective effects, researchers examined the antiulcer effects of 3,5,7-trihydroxy-2-(3,4-dihydroxyphenyl)-1-benzopyrylium chloride (IdB 1027,
an anthocyanidin from Vaccinium myrtillus) in various experimental models.
Orally, IdB 1027 inhibited all parameters associated with the onset of gastric ulcerations including anti-inflammatory drugs, ethanol, reserpine, histamine, and duodenal ulceration induced by mercaptamine.
Furthermore, IdB 1027 also protects the stomach against chronic gastric ulcers induced by acetic acid.
Moreover, IdB 1027 in the rat model did not affect gastric secretion in pylorus-ligated rats and increased gastric mucus in normal animals both in the absence and in the presence of indomethacin treatment.
In other words, IdB 1027 possessed a promising antiulcer activity, probably by potentiating the defensive barriers of the gastrointestinal mucosa.
Taken together, bilberry may be considered a functional remedy for the prevention and treatment of gastric ulcers, pending to the validation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) The protective effect and action mechanism of Vaccinium myrtillus L. on gastric ulcer in mice by Ogawa K1, Oyagi A, Tanaka J, Kobayashi S, Hara H. (PubMed)
(2) Antiulcer activity of an anthocyanidin from Vaccinium myrtillus by Magistretti MJ1, Conti M, Cristoni A. (PubMed)
(3) Obesity and Gastric Ulcers by Dr. Nadia B. Pietrzykowska. (OMC community)
Unpasteurized Frozen Pineapple Juice with Proteolytically Active Bromelain Enzymes process Anti Inflammatory Bowel Disease (IBD) Activity, Researchers Find
Kyle J. Norton
Inflammatory bowel disease (IBD) is a digestive condition characterized by an inflammation of the large intestine. The disease affects over 1.6 million Americans today.
The most common types of IBD are
*Crohn’s disease (CD) is an inflammation of any part of the digestive tract. Most cases of CD affect the tail end of the small intestine.
* Ulcerative colitis is an inflammation of the large intestine.
The exact causes of inflammatory bowel disease are unknown. However, some researchers do know that
* The disease may be caused by the weakened immune system that fails to kill off the invasion of infectious micro-organisms in the acute phase of digestive infection caused by tissue injury and damage.
* IBD may be a result of the immune dysfunction mistakenly attacking the digestive tract, a case of autoimmune disease.
* Imbalance of ratio of good and bad bacteria in the colon, caused by long-term intake of certain medicines.
* IBD is also associated with age, family history, ethnicity, parasite, and smoking.
* Genetic mutation of NOD2, ATG16L1and IL23R involved in innate immunity, in autophagy, and in the inflammatory response may also elevate the risk of IBD.
Believe it or not, if you are living in the Western world, you are also at a higher risk of the disease. For example, people who live in Western countries such as the United States and Europe have a higher IBD risk than those in other parts of the world.
Some researchers suggest an individual diet pattern may influence the risk of IBD.
Dr. Donjete Statovci, the lead scientist wrote, "Westernized diet, defined as high dietary intake of saturated fats and sucrose and low intake of fiber, represent a growing health risk contributing to the increased occurrence of metabolic diseases, e.g., diabetes and obesity in countries adopting a westernized lifestyle. Inflammatory bowel diseases (IBD) and asthma are chronic mucosal inflammatory conditions of unknown etiology with increasing prevalence worldwide".
And, "Recent reports indicate that the gut microbiota and modifications thereof, due to the consumption of a diet high in saturated fats and low in fibers, can trigger factors regulating the development and/or progression of both conditions".
In other words, by pursuing a healthy diet with a higher in fruits and vegetables and reducing intake of red meat, saturated and trans fat, and processed foods, IBD is preventable.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
In an aim to find the potential compound for the treatment of inflammatory bowel disease, researchers examined the efficacy of bromelain in colitis in an animal study.
According to the tested assays, daily treatment with oral bromelain at the age of 5 weeks showed a significant effect on decreasing the incidence and severity of spontaneous colitis in C57BL/6 IL-10-/- mice.
Furthermore, bromelain also significantly decreased the severity of colonic inflammation by inhibiting the production of the pro-inflammatory cytokine in mice colitis induced by piroxicam exposure.
Moreover, bromelain anti-inflammatory effects were associated with the exertion of proteolytical activity.
In wild-type mice treated orally with up to 1000 mg bromelain/kg/day for 18 weeks, researchers do not observe ant adverse effects such as dermatitis, hair loss, and weight loss due to mucositis.
Based on the findings, researchers wrote, " the results justify additional studies of this complementary biologically based approach to the treatment of IBD".
Also in the animal model, short-term oral treatment with bromelain was found to decrease the severity of colonic inflammation in C57BL/6 Il10(-/-) mice with chronic colitis.
Mice treated with fresh pineapple juice at a level equivalent to 14 mg bromelain purified from the stem decreased histologic colon inflammation scores and a lower incidence of inflammation-associated colonic neoplasia (35% versus 66%; P < 0.02), with fewer neoplastic lesions/colon.
According to the flow cytometric analysis, murine splenocytes exposed to fresh pineapple juice in vitro affect leukocyte trafficking and activation in facilitating the production of pro-inflammatory cytokines associated with immune response.
Dr. Hale LP, the lead scientist after taking into account co and confounders wrote, "Long-term dietary supplementation with fresh or unpasteurized frozen pineapple juice with proteolytically active bromelain enzymes is safe and decreases inflammation severity and the incidence and multiplicity of inflammation-associated colonic neoplasia in this commonly used murine model of inflammatory bowel disease".
Taken together, bromelain may be considered a remedy for the prevention and treatment of inflammatory bowel disease, pending the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Treatment with oral bromelain decreases colonic inflammation in the IL-10-deficient murine model of inflammatory bowel disease by Hale LP1, Greer PK, Trinh CT, Gottfried MR. (PubMed)
(2) Dietary supplementation with fresh pineapple juice decreases inflammation and colonic neoplasia in IL-10-deficient mice with colitis by Hale LP1, Chichlowski M, Trinh CT, Greer PK. (PubMed)
(3) The Impact of Western Diet and Nutrients on the Microbiota and Immune Response at Mucosal Interfaces by Donjete Statovci,1 Mònica Aguilera,1 John MacSharry,1,2 and Silvia Melgar. (PMC)
Inflammatory bowel disease (IBD) is a digestive condition characterized by an inflammation of the large intestine. The disease affects over 1.6 million Americans today.
The most common types of IBD are
*Crohn’s disease (CD) is an inflammation of any part of the digestive tract. Most cases of CD affect the tail end of the small intestine.
* Ulcerative colitis is an inflammation of the large intestine.
The exact causes of inflammatory bowel disease are unknown. However, some researchers do know that
* The disease may be caused by the weakened immune system that fails to kill off the invasion of infectious micro-organisms in the acute phase of digestive infection caused by tissue injury and damage.
* IBD may be a result of the immune dysfunction mistakenly attacking the digestive tract, a case of autoimmune disease.
* Imbalance of ratio of good and bad bacteria in the colon, caused by long-term intake of certain medicines.
* IBD is also associated with age, family history, ethnicity, parasite, and smoking.
* Genetic mutation of NOD2, ATG16L1and IL23R involved in innate immunity, in autophagy, and in the inflammatory response may also elevate the risk of IBD.
Believe it or not, if you are living in the Western world, you are also at a higher risk of the disease. For example, people who live in Western countries such as the United States and Europe have a higher IBD risk than those in other parts of the world.
Some researchers suggest an individual diet pattern may influence the risk of IBD.
Dr. Donjete Statovci, the lead scientist wrote, "Westernized diet, defined as high dietary intake of saturated fats and sucrose and low intake of fiber, represent a growing health risk contributing to the increased occurrence of metabolic diseases, e.g., diabetes and obesity in countries adopting a westernized lifestyle. Inflammatory bowel diseases (IBD) and asthma are chronic mucosal inflammatory conditions of unknown etiology with increasing prevalence worldwide".
And, "Recent reports indicate that the gut microbiota and modifications thereof, due to the consumption of a diet high in saturated fats and low in fibers, can trigger factors regulating the development and/or progression of both conditions".
In other words, by pursuing a healthy diet with a higher in fruits and vegetables and reducing intake of red meat, saturated and trans fat, and processed foods, IBD is preventable.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
In an aim to find the potential compound for the treatment of inflammatory bowel disease, researchers examined the efficacy of bromelain in colitis in an animal study.
According to the tested assays, daily treatment with oral bromelain at the age of 5 weeks showed a significant effect on decreasing the incidence and severity of spontaneous colitis in C57BL/6 IL-10-/- mice.
Furthermore, bromelain also significantly decreased the severity of colonic inflammation by inhibiting the production of the pro-inflammatory cytokine in mice colitis induced by piroxicam exposure.
Moreover, bromelain anti-inflammatory effects were associated with the exertion of proteolytical activity.
In wild-type mice treated orally with up to 1000 mg bromelain/kg/day for 18 weeks, researchers do not observe ant adverse effects such as dermatitis, hair loss, and weight loss due to mucositis.
Based on the findings, researchers wrote, " the results justify additional studies of this complementary biologically based approach to the treatment of IBD".
Also in the animal model, short-term oral treatment with bromelain was found to decrease the severity of colonic inflammation in C57BL/6 Il10(-/-) mice with chronic colitis.
Mice treated with fresh pineapple juice at a level equivalent to 14 mg bromelain purified from the stem decreased histologic colon inflammation scores and a lower incidence of inflammation-associated colonic neoplasia (35% versus 66%; P < 0.02), with fewer neoplastic lesions/colon.
According to the flow cytometric analysis, murine splenocytes exposed to fresh pineapple juice in vitro affect leukocyte trafficking and activation in facilitating the production of pro-inflammatory cytokines associated with immune response.
Dr. Hale LP, the lead scientist after taking into account co and confounders wrote, "Long-term dietary supplementation with fresh or unpasteurized frozen pineapple juice with proteolytically active bromelain enzymes is safe and decreases inflammation severity and the incidence and multiplicity of inflammation-associated colonic neoplasia in this commonly used murine model of inflammatory bowel disease".
Taken together, bromelain may be considered a remedy for the prevention and treatment of inflammatory bowel disease, pending the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Treatment with oral bromelain decreases colonic inflammation in the IL-10-deficient murine model of inflammatory bowel disease by Hale LP1, Greer PK, Trinh CT, Gottfried MR. (PubMed)
(2) Dietary supplementation with fresh pineapple juice decreases inflammation and colonic neoplasia in IL-10-deficient mice with colitis by Hale LP1, Chichlowski M, Trinh CT, Greer PK. (PubMed)
(3) The Impact of Western Diet and Nutrients on the Microbiota and Immune Response at Mucosal Interfaces by Donjete Statovci,1 Mònica Aguilera,1 John MacSharry,1,2 and Silvia Melgar. (PMC)
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