Monday, 9 October 2023

#ChineseCabbage Reduces the Incidence of Liver Cancer Induced by Aflatoxin B1, Researchers Find

Kyle J. Norton

The liver is the largest internal organ found in the human which plays an essential role in filtering the blood from the digestive system before passing it to other parts of the body.

The liver also produces cholesterol, a waxy substance that aids digestion, builds cell membranes, and produces vitamin D and steroid hormones.

Liver disease is a class of medical conditions characterized by the reduction of partly or completely the function of the liver, including liver failure.

Liver cancer is a medical condition characterized by cell growth irregularly in the liver tissue.

Liver cancer at an early stage does not cause any symptoms. However, at the advanced stage, liver cancer cells can cause a wide range of symptoms including jaundice, abdominal swelling and pain, and dark urine and white stool accompanied by the general symptoms of cancers such as unintended weight loss, loss of appetite, chronic fatigue and tiredness and gastrointestinal discomforts.

The causes of liver cancer are associated with the alternation of cell DNA which normally begins in the cells on the surface of the inner lining.

The most common risk factor of liver cancer is infected by the hepatitis virus. However, in North America, due to the overexpression of the overweight and obese population, liver cancer may slowly progress from nonalcoholic fatty liver disease through cirrhosis to liver cancer.


According to the statistics provided by the Canadian Cancer Society, every year, approximately, 1,900 men and 580 women are diagnosed with liver cancer, causing the death of 950 men and 270 women.

In 2017, 2,500 Canadians were diagnosed with liver cancer and 1,200 Canadians died from liver cancer.

Compared to the early stage of other cancers, the 5 years survival rate in the early stage diagnosis is only 31%, and 43% of people with liver cancer are diagnosed at stages 0 and 1.

In finding a potential plant that processes anti-invasive tumor activity researchers compared the potential anticancer ability of Chinese cabbage powder, which is a complex water-soluble extract from Chinese cabbage by spray-drying at an outlet temperature of 130 °C on liver cancer.
According to the chemical analysis, Chinese cabbage powder processed at least 11 potential anticancer substances.

In a 90-day animal experiment, 10% of Chinese cabbage powder in drinking water could improve the plasma micronutrient status, and inhibit the formation of aflatoxin B1-DNA adducts in liver cells in the initiation of tumor growth.

Furthermore, in vivo, 10% of Chinese cabbage powder effectively reduced the incidence of liver tumors induced by aflatoxin B1 from 6.67% to 0%.

The dose analysis assays suggested that 10% may be the minimal effective dose to prevent the occurrence of early liver tumors.

Collectively, researchers wrote, "This study will help elucidate the basis of epidemiological observations of dietary cancer prevention in humans, as well as explore related mechanisms".

Taken together, Chinese cabbage may be considered a functional food for the prevention and treatment of liver cancer, pending the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Inhibition effects of Chinese cabbage powder on aflatoxin B1-induced liver cancer by Wang T1, Li C2, Liu Y2, Li T3, Zhang J4, Sun Y. (PubMed)

#CynometraCauliflora Inhibits Parameters Associated with the Onset of Obedity, Researchers Say

Kyle J. Norton

Obesity is a chronic medical condition caused by excess body fat accumulated to some extent that impacts personal health. The hallmark of obesity is attenuated metabolism and structural cell changes in the obese fat observed by reducing metabolic activity.

According to the statistics provided by the National Center for Health Statistics (2015-2016), in the US, approximately 39.8% of adults aged 20 and over were obese accompanied by another 31.8% overweight.

Visceral fat is a layer of fat that surrounds the organs. Overexpression of visceral fat has been found to promote insulin resistance, diabetes, heart disease, and inflammation.


In obese, accumulation of visceral fat is predominant in the intra-abdominal cavity.


According to the BMI index, a person is considered overweight, if he/she has a BMI between 25 to 29.9 kg/m2. A BMI of 30 kg/m2 or more is an indication of obesity.

In other words, obesity is a progressive chronic disease characterized by abnormal fat accumulation in the body tissues that may impair health.

Similar to other chronic medical conditions including diabetes, cardiovascular disease, or high blood pressure, obesity has recently become a serious health problem in the US as nearly 35% of Americans are obese accompanied by a similar percentage of overweight adults.

Obesity and overweight in the U.S. economy have eclipsed $1.7 trillion, equivalent to 9.3 percent of the nation's gross domestic product, according to a new overweight report on chronic diseases.


Dr. Maximilian Tremmel, the lead scientist in a systematic literature review of the economic burden of obesity, wrote, "Almost half of the world’s adult population will be overweight or obese by 2030 if the prevalence continues on the current trend [6] and consequently also the costs attributable to obesity will increase"

And, "A useful example of rapidly rising costs attributable to obesity from these selected studies are the two mentioned studies from Germany [44,46]. The results of the two papers together show that total societal costs in Germany due to obesity have increased from €9.8 million to €12.2 million between 2002 and 2008. Therefore, public health interventions should focus on the prevention of obesity as soon as possible, ideally at a young age".


Description
Cynometra cauliflora is a species of the genus Cynometra, native to Malaysia, and found mainly in northern Peninsular Malaysia.

In finding a potential phytochemical for the prevention and treatment of chronic diseases, researchers examined the anti-obesity and lipid-lowering effects of ethanolic extract of C. cauliflora leaves and its major compound (vitexin) in C57BL/6 obese mice induced by high-fat diet (HFD).

The study included male C57BL/6 mice induced obesity by feeding with HFD (60% fat) for 16 weeks followed by the treatment that starts during the last 8 weeks of HFD feeding with C. cauliflora leaf extract at 200 and 400 mg/kg/day, orlistat (10 mg/kg) and vitexin (10 mg/kg).

According to the chemical analysis,
* The oral administration of C. cauliflora (400 and 200 mg/kg) and vitexin significantly reduced body weight, adipose tissue and liver weight, and lipid accumulation in the liver compared to the control HFD group.

* Both doses of C. cauliflora also significantly (P ≤ 0.05) decreased serum triglyceride, LDL, lipase, IL-6, peptide YY, resistin levels, hyperglycemia, hyperinsulinemia, and hyperleptinemia compared to the control HFD group.

* C. cauliflora significantly up-regulated the expression of adiponectin, Glut4, Mtor, IRS-1, and InsR genes associated with sustaining weight loss and significantly decreased the expression of Lepr in white adipose tissue involved in stimulating weight gain.

Based on the findings, researchers said, "This study shows interesting outcomes of C. cauliflora against HFD-induced obesity and associated metabolic abnormalities".

Taken altogether, beta-sitosterol may be considered a supplement for the prevention and treatment of bacterial infectious diseases, pending the confirmation of the larger sample size and multicenter human study.

Intake of beta-sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Cynometra cauliflora Linn. Attenuates metabolic abnormalities in high-fat diet-induced obese mice by Seyedan A1, Mohamed Z2, Alshagga MA3, Koosha S4, Alshawsh MA. (PubMed)
(2) Economic Burden of Obesity: A Systematic Literature Review by Maximilian Tremmel,1,* Ulf-G. Gerdtham,2,3,4 Peter M. Nilsson,5 and Sanjib Saha. (PMC)

Intake of #CruciferousVegetables Daily and Regularly Shows an Inverse Association with the Risk of Coronary Heart Disease, According to Studies

Kyle J. Norton

Heart diseases are a medical condition associated with any disruption of blood vessels and heart function.
There are 5 types of heart diseases, including
* Heart disease affected by the arteries to the heart, such as coronary artery heart disease.

* heart disease affected by heart valve functions in regulating blood flow such as valvular heart disease.

* heart disease affects electrical conduction such as arrhythmias.

* Heart disease affected by heart muscles such as cardiomyopathy. And

* Congenital heart disease caused by heart defect at birth

According to the statistics, heart disease is the leading cause of death in the US, approximately 610,000 people die of heart disease every year.

Coronary heart disease (CHD) kills over 370,000 people annually.


Furthermore, the most common heart disease in North America is CHD, the type of heart disease caused by plaque buildup on artery walls, leading to narrow, thickened, and stiffened arteries. Some researchers suggested that the causes of plaque build-up on the arterial wall were the results of several factors including an unhealthy diet, lack of exercise, being overweight, and smoking.

What causes plaques to build up on the arterial is debatable. However, researchers suggested that the Western diet is associated with a significantly increased risk of coronary artery disease.

Dr. Venegas-Pino DE in the classification of the effect of diet on heart diseases said," the western-diet-fed male ApoE-/-: Ins2+/Akita mouse, with profound cardiovascular disease involving extensive atherosclerosis, coronary artery disease, and myocardial infarct resulting in shortened lifespan(4)".

The most common symptoms of coronary artery disease are angina, the condition characterized by chest pain or discomfort, and shortness of breath as a result of the weakening of the heart muscle which can not pump enough blood to the body's needs.

Over time, the prolonged weakened heart muscle can lead to complications of heart failure, irregular heartbeat, or arrhythmia.

Cruciferous vegetables are a group of vegetables, belongings to the family Brassicaceae (also called Cruciferae) with many genera, and species, and cultivated all over the world in suitable climates for commercial profits, including cauliflower, cabbage, kale, garden cress, bok choy, broccoli, Brussels sprouts, and green leafy vegetables.

In finding a potential remedy for the prevention of plaque accumulated on the arterial wall, researchers investigated the association of intake of glucosinolates with the risk of coronary heart disease (CHD).

A total of 74,241 women in the Nurses' Health Study (NHS; 1984-2012), 94,163 women in the NHSII (1991-2013), and 42,170 men in the Health Professionals Follow-Up Study (1986-2012), who were free of cardiovascular disease and cancer at baseline were given Glucosinolate intake that was assessed using validated semi-quantitative food frequency questionnaires at baseline and updated every 2-4 years during follow-up.


According to the food questionnaire returned
* During 4,824,001 person-years of follow-up, 8,010 cases of CHD were identified in the three cohorts.

* After adjustment for major lifestyle and dietary risk factors of CHD, weak but significant positive associations were observed for glucosinolates with CHD risk when comparing the top with bottom quintiles (hazard ratio [HR]:1.09; 95% CI: 1.01, 1.17; Ptrend<0.001).


* Higher intakes of three major subtypes of glucosinolates were consistently associated with a higher CHD risk, although the association for indolyl glucosinolates did not achieve statistical significance. Regarding cruciferous vegetable intake.

Moreover, participants who consumed one or more servings per week of Brussels sprouts (HR: 1.16; 95% CI: 1.06, 1.26; P<0.001) and cabbage (HR: 1.09; 95% CI: 1.02, 1.17; P=0.009) had a significantly higher CHD risk than those who consumed these cruciferous vegetables less than once per month.

Based on the results, researchers said, " dietary glucosinolate intake was associated with a slightly higher risk of CHD in US adults".

Taken together, cruciferous vegetables may be considered functional remedies for the prevention of coronary heart disease, pending the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye FloatersContrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How to Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Intake of glucosinolates and risk of coronary heart disease in three large prospective cohorts of US men and women by Ma L1,2, Liu G1, Zong G1, Sampson L1, Hu FB1,3,4, Willett WC1,3,4, Rimm EB1,3,4, Manson JE3,5,6, Rexrode KM6, Sun Q. (PubMed)
(2) Evidence of extensive atherosclerosis, coronary artery disease, and myocardial infarction in the ApoE-/-:Ins2+/Akita mouse fed a western diet by Venegas-Pino DE1, Lagrotteria A2, Wang PW3, Morphet J3, Clapdorp C3, Shi Y3, Werstuck GH(PubMed)

#Ginger #Extract Processes Antibiofilm Formation Associated with a Reduced Risk of Infectious Diseases, Reserachers Show

Kyle J. Norton

Scientists may have a kitchen remedy that processes the potential to improve the immune function against infection, some studies suggested.

A biofilm is a system that can be adapted internally to environmental conditions by its inhabitants. In other words, biofilm-forming from bacteria is one of the common forms of bacterial infection affecting up to 80% of human bacterial infections.

In biology, biofilm is used by bacteria as a natural defense mechanism of bacteria to survive under harsh environments, by attaching to a solid surface in a large community, including the skin, teeth, and mucosa.

Bacterial initiate biofilm formation with an aim to greatly enhance survival in hosts and cause chronic infections, leading to long-term inflammation and tissue damage.

The formation of a biofilm of bacteria may go through 2 stages, the adhesion phase is the stage in the bacteria attach to the surface or accumulate on a surface, After the adhesion phase, the bacteria enter the colonial phase, where the bacteria continue to grow, leading to the formation of dense bacterial aggregates.

Dr. Li XH, the lead scientist in examining the new anti-biofilm agents, said, "In biofilms, microorganisms become much more resistant to antimicrobial treatments, harsh environmental conditions, and host immunity".

And, "Currently, it is believed over 80% of chronic infectious diseases are mediated by biofilms, and it is known that conventional antibiotic medications are inadequate at eradicating this biofilm-mediated infection".

Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.

The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.

Scientists on finding a natural compound with anti-biofilm activity for the treatment of microbial infection evaluated the ginger anti-biofilm formation effects.

Injection of ginger exerted a strong inhibition against Pseudomonas aeruginosa PA14 biofilm formation.


The anti-biofilm activity of ginger caused a reduction of 39–56% when the ginger extract was added to the culture.

The ginger extract also decreased the production of extracellular polymeric substances, the fundamental component that determines the physiochemical properties of a biofilm, according to chemical analysis and confocal laser scanning microscopy.

Furthermore, ginger extract formed noticeably less rugose colonies on agar plates containing Congo red and facilitated swarming motility on soft agar plates.

The ginger extract also inhibited biofilm formation in both Gram-positive and Gram-negative bacteria.


The efficacy of ginger extract was attributed to the reduced level of a second messenger, bis-(3′-5′)-cyclic dimeric guanosine monophosphate in the induction of biofilm formation.

Also, surface biofilm cells formed with ginger extract detached more easily with surfactant than did those without ginger extract.

The results strongly support the use of ginger as a broad-spectrum biofilm inhibitor, in the reduction of bacterial biofilm formation, a major cause of serious health problems.

In order to reveal more information about the ginger effect against biofilm formation, researchers examined the bioactive compounds on Candida albicans.

6-gingerol, 8-gingerol, and 6-shogaol effectively inhibited biofilm formation, and 6-shogaol at 10 μg/ml significantly reduced C. Albicans biofilm formation with no harm to the planktonic cell growth.

Moreover, 6-gingerol and 6-shogaol inhibited hyphal growth in embedded colonies and free-living planktonic cells and prevented cell aggregation.


Additionally, 6-gingerol and 6-shogaol reduced C. Albicans virulence in a nematode infection model without causing toxicity at the tested concentrations.

Dr. Jin-Hyung Lee,, the lead scientist wrote in the final report, "These results highlight the anti-biofilm and antivirulence activities of the ginger components, 6-gingerol, and 6-shogaol, against a drug-resistant C. Albicans strain".

Taken altogether, ginger processed with a high amount of bioactive compounds may be considered a functional remedy for the prevention of bacterial infection by inhibiting the biofilm activity of micro pathogens.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.

Sources
(1) Ginger Extract Inhibits Biofilm Formation by Pseudomonas aeruginosa PA14 by Han-Shin Kim and Hee-Deung Park. (PMC)
(2) Antibiofilm and Antivirulence Activities of 6-Gingerol and 6-Shogaol Against Candida albicans Due to Hyphal Inhibition by Jin-Hyung Lee,1,† Yong-Guy Kim,1,† Pilju Choi,2 Jungyeob Ham,2 Jae Gyu Park,3,* andJintae Lee. (PMC)
(3) Antibiofilm agents: A new perspective for antimicrobial strategy by Li XH1, Lee JH2. (PubMed)

#GreenLeafyVeggies Lower the Risk of Cardiovascular Disease and Cancer, According to Studies

Kyle J. Norton

Bile acids are synthesized by oxidation from cholesterol in the liver, flowing to the gallbladder to aid digestion.
Cholesterol is a waxy substance that is produced either by the liver or injected from animal food sources.

Cholesterol found in our body is needed for our body to build cell walls, hormones, and vitamin D, and create bile salts that aid digestion. However, too much of them, in most cases due to the intake of animal protein can cause plaques to build up on the arterial wall, the major cause of heart disease and stroke.

Bile acid-binding is a process that interferes with normal fat digestion and absorption including the prevention of absorption of fat-soluble vitamins such as A, D, E, and K.

In other words, the binding of bile acids (BAs) may have a strong effect on lowering blood cholesterol levels by increasing the excretion of bile acids in the stool and reducing the amount of bile acid returning to the liver.

By inhibiting the levels of bile acid caused by a certain type of liver/bile duct disease such as partial biliary obstruction, levels of cholesterol can be controlled.

Conventionally, the effects of bile acid sequestrants are limited. Low doses of 8 grams/day of Cholestyramine, a bile acid sequestrant, which binds bile in the gastrointestinal tract to prevent its reabsorption can lower LDL cholesterol by 10%-15% compared to high doses of 24 grams/day of only 25%.

In other words, bile acid-binding medicines such as Cholestyramine, used alone are less effective, compared to statins in lowering LDL cholesterol.

The most common symptoms associated with the intake of Cholestyramine are constipation, diarrhea, stomach/abdominal pain, bloating, nausea, vomiting, and loss of appetite.

In finding a potential plant that processes anti-high blood cholesterol activity, researchers compared the bile acid-binding potential that lowers the risk of heart disease and cancer of various vegetables.

Compared to Cholestyramine (a cholesterol-lowering, bile acid-binding drug) that was used as the positive control treatment and cellulose as the negative control, researchers found that* Relative to cholestyramine, in vitro bile acid binding on dry matter basis was for the collard greens, kale, and mustard greens, 13%; broccoli, 10%; Brussels sprouts and spinach, 8%; green bell pepper, 7%; and cabbage, 5%.

In other words, collard greens = kale = mustard greens showed the strongest healthy-promoting potential in bile acid-binding compared to the following lesser extent of > broccoli > Brussels sprouts = spinach = green bell pepper > cabbage.

More importantly, steam cooking significantly improved the in vitro bile acid binding of collard greens, kale, mustard greens, broccoli, green bell pepper, and cabbage compared to vegetables raw (uncooked).

More precisely, the Inclusion of steam-cooked collard greens, kale, mustard greens, broccoli, green bell pepper, and cabbage in our daily diet may have the potential to improve healthy levels of blood cholesterol.

Collectively, researchers said, "These green/leafy vegetables, when consumed regularly after steam cooking, would lower the risk of cardiovascular disease and cancer, advance human nutrition research, and improve public health".

Taken together, green leafy veggies may be considered functional foods for lowering blood cholesterol, pending the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Steam cooking significantly improves in vitro bile acid binding of collard greens, kale, mustard greens, broccoli, green bell pepper, and cabbage by Kahlon TS1, Chiu MC, Chapman MH. (PubMed)

#RapeseedOil Reduces Body Weight and Metabolic Factors Associated with Cardiovascular Risk, According to Studies

Kyle J. Norton

A dietary pattern is the measurement of the quantity, variety, or combination of different foods and beverages in a diet as well as the frequency of the foods that are habitually consumed.
The most common dietary patterns are
* The traditional diet, Wikipedia wrote, "Traditional foods are foods and dishes that are passed through generations or which have been consumed many generations. Traditional foods and dishes are traditional in nature, and may have a historic precedent in a national dish, regional cuisine, or local cuisine".

* The Western diet is a standard American diet (SAD) associated with high intakes of red meat, processed meat, pre-packaged and refined foods, fried foods, high-fat dairy products, and high salt, and sugar foods.

Metabolic syndrome is a cluster of conditions associated with the increased risk of cardiovascular disease and diabetes.

The health problems found in the group include too much fat around the waist, elevated blood pressure, high triglycerides, elevated blood sugar, and low HDL cholesterol.

In other words, if you have 3 of the conditions in the group, your risk of CVD and diabetes is increased substantially compared to those who have less.

According to the statistics, approximately 30% of people in the US are living with metabolic syndrome.

Believe it or not, among US adults aged 18 years or older, the prevalence of metabolic syndrome rose by more than 35% from 1988–1994 to 2007–2012, increasing from 25.3% to 34.2%.

Rapeseed, also known as rape, or oilseed rape, is a member of the family Brassicaceae (mustard or cabbage family), cultivated in suitable climate regions for its oil-rich seed for commercial profits.

In finding a potential compound for the prevention of heart disease, researchers at the University of Applied Sciences investigated the effects of a hypoenergetic diet with low energy density (ED) enriched in rapeseed oil-derived n-3 fatty acid α-linolenic acid (ALA), in patients with metabolic syndrome.

The human trial included eighty-one patients with metabolic syndrome randomly assigned to receive either rapeseed oil derived with high MUFA content and an ALA intake of 3.5 g/d on body weight or olive oil diet rich in MUFA but with a low ALA content.

According to the results, after a 6-month dietary intervention, the rapeseed oil and olive oil groups showed a significant in reduced body weight and metabolic factors associated with cardiovascular risk.

In other words, intervention groups with rapeseed oil not only significantly decrease the systolic blood pressure, but also reduce total cholesterol LDL-cholesterol, and insulin levels in patients with metabolic syndrome.


More interestingly, serum triglycerides (TAG) associated with cardiovascular and nonfatty liver disease risk factors were significantly reduced only in the high ALA intake, compared to no effect on the low ALA group.

Based on the findings, researchers said, "Our dietary food pattern with a low ED and high intakes of MUFA and ALA may be a practical approach for long-term dietary treatment in patients with the metabolic syndrome".

Taken together, rapeseed oil may be considered a supplement for the prevention and treatment of metabolic syndrome, pending the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Effects of a rapeseed oil-enriched hypoenergetic diet with a high content of α-linolenic acid on body weight and cardiovascular risk profile in patients with the metabolic syndrome by Baxheinrich A1, Stratmann B, Lee-Barkey YH, Tschoepe D, Wahrburg U. (PubMed)

#Herbal #Angelica Sinensis Inhibits Glioma Cells Growth and Proliferation, According to Studies

Kyle J. Norton

A glioma is a type of brain and spinal cord tumor characterized by the alternation of DNA of the glial cells.
Believe it or not, gliomas have been found to account for 30 percent of all brain tumors and central nervous system tumors, and 80 percent of all malignant brain tumors.

Glioma can be classified into 3 types, including
* Astrocytomas are found in glial cells, star-shaped brain cells in the cerebrum called astrocytes. Most astrocytomas are localized.

* Ependymomas are cancers that grow in your brain or any part of the spine, including your neck and upper and lower back starting from the ependymal cells in the middle of your spinal cord and fluid-filled spaces in your brain.

* Oligodendrogliomas are cancers that begin on the oligodendrocytes of the brain or from a glial precursor cell.

Primary glioblastoma is considered the most aggressive cancer that begins within the brain. Cancer may arise de novo, meaning it begins as a Grade IV tumor with no evidence.

According to the statistics, the median survival time of primary glioblastoma is approximately 3 months without medical treatment. Glioblastomas represent about 15% of all primary brain tumors.

Due to the rapid growth of the tumor, patients diagnosed with primary glioblastoma experience brain swelling and increased brain pressure, leading to symptoms of nausea, vomiting, severe headaches, and localized symptoms depending on the location of the tumor.

Radiation and chemotherapy are the most common forms of treatment for patients with glioblastoma particularly, in a tumor that cannot be removed with surgery.


In finding a natural ingredient for the prevention and treatment of neurological diseases, scientists examined the inhibitory effects of Angelica polysaccharides (APs), bioactive constituents of Angelica on a glioma cell line.

Angelica or Dang Gui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.

The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen the heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.

According to tested analysis of both in vitro and in vivo models,
* APs exerted a significant inhibition of the growth and proliferation of U251 cells and induced their apoptosis.

* APs effectively reduced the expression of several cell cycle regulators such as cyclins D1, B, and E in the induction of cell cycle division of the tested cell line.

* APs also inhibited the anti-apoptotic protein Bcl-2 and increased the expression of pro-apoptotic proteins Bax and cleaved-caspase-3.

* Most importantly, APs inhibited the transforming growth factor (TGF)-β signaling pathway and stimulated the expression of E-cadherin, associated with the inhibition of cell growth.

Based on the results, researchers suggest, " the results indicate that APs attenuate the tumorigenicity of glioma cells and promote their apoptosis by suppressing the TGF-β signaling pathway".

Taken together, Dandelion may be considered a neuroprotective remedy, pending the confirmation of the larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Angelica polysaccharides inhibit the growth and promote the apoptosis of U251 glioma cells in vitro and in vivo by Zhang WF1, Yang Y1, Li X1, Xu DY1, Yan YL1, Gao Q1, Jia AL1, Duan MH. (PubMed)