Monday, 2 October 2023

#Cabbage #Extract Inhibits CardiovascularDisease Agaisnt Oxidative Stress, Researchers Suggest

Kyle J. Norton

The expression of oxidative stress is a medical condition characterized by the imbalance of the ratio of free radicals and antioxidant enzymes produced by the host tissue.

In some cases, this reaction also causes long-term accumulation of toxic substances in the body, such as lead, cadmium, mercury, and arsenic.

Dr. Ercal N, the lead author in the study of the relation of toxic metals and oxidative stress, wrote, "Antioxidants may play an important role in abating some hazards of heavy metals. In order to prove the importance of using antioxidants in heavy metal poisoning, pertinent biochemical mechanisms for metal-induced oxidative stress".

There is no single cause of oxidative stress. Some researchers suggested that a number of factors can facilitate the onset of oxidative stress, including cigarette smoke, oxidative bursts from activated macrophages, particularly, the free radicals chain reaction.

Sadly, a prolonged period of oxidative stress presented in the human body can cause oxidative damage to biomolecules, (lipids, proteins, DNA) and the death of healthy cells through cytotoxicity.

Liver oxidative stress markers such as serum MDA refer to oxidative stress in the liver tissues caused by the overexpression of free radicals or reduced levels of antioxidant enzymes in the liver.


Dr. Halina Cichoż-Lach, the lead scientist said, "Redox state constitutes an important background of numerous liver disorders. The redox state participates in the course of inflammatory, metabolic and proliferative liver diseases.".

And, "Hepatocytic proteins, lipids, and DNA are among the cellular structures primarily affected by ROS and reactive nitrogen species. The process results in structural and functional abnormalities in the liver".

In other words, liver oxidative stress over the long-term induced damage of proteins, and lipid and alternation of cell DNA can lead to liver diseases, including cancer.

Cabbage is a species of Brassica oleracea belonging to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem with a crowded mass of leaves, usually green but in some varieties, it may be red or purplish.

In finding a natural wholefood for the treatment of cardio-diseases, researchers examined the effects of cabbage extract on oxidative stress in H9c2 cardiomyoblasts.


Based on the results of the experiment,* Cabbage extract protected against H2O2-induced cell death and did not elicit any cytotoxic effects.

* Cabbage extract suppressed ROS production and increased expression of antioxidant proteins (SOD-1, catalase, and GPx).

* Cabbage extract also inhibited apoptotic responses and activation of MAPK proteins in initiating cellular response in oxidative stress-exposed H9c2 cells.


* Cabbage extract preserved mitochondrial functions upon oxidative stress.

Based on the results, researchers wrote, "Cabbage extract protects against oxidative stress and suggests that it can be used as an alternative therapeutic strategy to prevent the oxidative stress in the heart".

Taken together, cabbage may be used to treat oxidative stress-induced cardiovascular diseases, pending confirmation of the larger sample size and multicenter human study.


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Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Cabbage (Brassica oleracea var. capitata) Protects against H2o2-induced oxidative Stress by Preventing Mitochondrial Dysfunction in H9c2 Cardiomyoblasts by Yang DK. (PubMed)
(2) Oxidative stress as a crucial factor in liver diseases by Halina Cichoż-Lach and Agata Michalak (PMC)

Sunday, 1 October 2023

#Greentea #Polyphenols (GTP) Supplement and/or Tai Chi Show a Protective Effect on Bone health, Reserachers Show

Kyle J. Norton

Evidence from laboratory studies opinionated, that regular drinking of green tea improved bone health and reduced the risk of osteoporosis and fractures.

Bone health is measured by bone mineral density which has a direct influence on the risk of osteoporosis and fractures.

Green tea, a precious drink processes a number of health benefits known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine, or food, long-term injection of large amounts may obstruct the balance of yin-yang, inducing "yin excessive syndrome" or "yang vacuity syndrome" including weakened immunity and painful cases of GERD,... according to traditional Chinese medicine's Yin-Yang theory. But adding a slice of ginger will benign the problem.

According to the Texas Tech University Health Sciences Center, green tea lovers have a reduced risk of lower bone mineral density due to its bioactive components with bone-protective properties.


The study also found that regular green tea drinking promotes bone health in bone mineral loss menopausal women through increased bone mass, thus reducing the risk of osteoporosis, a common disease in the aging population.


Furthermore, the intake of green also protected the early onset of bone mineral loss in obese subjects.

Another study conducted by the same group of researchers also stated the bone density protective effect of green tea may involve the bioactive components' effects in decreasing the risk of fracture by supporting osteoblastic activities while suppressing osteoclastic activities as well as attenuating oxidative stress in promoting healthy levels of bone mineral density.

In the postmenopausal osteopenic women study, green tea with an optimized dose of polyphenols showed an enhanced osteoprotective efficacy in improved bone mass, microarchitecture integrity, and bone strength observed through the advanced imaging technology.


Dr, Shen CL, the lead author in the studies said, " Tea polyphenols enhance osteoblastogenesis and suppress osteoclastogenesis in vitro" and "Animal studies reveal that intake of tea polyphenols have pronounced positive effects on bone as shown by higher bone mass and trabecular bone volume, number, and thickness and lower trabecular separation via increasing bone formation and inhibition of bone resorption, resulting in greater bone strength".


Promisingly, in a total study of 171 postmenopausal osteopenic women to compare the efficacy of green tea polyphenols (GTP) supplement and/or Tai Chi in the risk of osteoporosis, randomly assigned to four groups: (1) placebo (500 mg starch/day), (2) GTP (500 mg GTP/day), (3) placebo + TC (placebo plus TC training at 60 min/session, three sessions/week), and (4) GTP + TC (GTP plus TC training).for 6 months, intake of green and tai chi exercise groups increased bone-specific alkaline phosphatase(bone protective glycoprotein found on the surface of osteoblasts) and improved BAP/(tartrate-resistant acid phosphatase, osteoclast increased risk of bone turnover)/TRAP ratio.

Additionally, the group that received green tea showed significantly improved muscle strength in postmenopausal women with osteopenia.


Taken together, green tea may be served as a functional food to protect bone mineral density in all people with/ without risk of osteoporosis.


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Sources
(1) Green tea and bone health: Evidence from laboratory studies by Shen CL1, Yeh JK, Cao JJ, Chyu MC, Wang JS. (PubMed)
(2) Green tea and bone metabolism by Shen CL1, Yeh JK, Cao JJ, Wang JS. (PubMed)
(3) Tea and bone health: steps forward in translational nutrition by Shen CL1, Chyu MC, Wang JS.(PubMed)
(4) Effect of green tea and Tai Chi on bone health in postmenopausal osteopenic women: a 6-month randomized placebo-controlled trial by Shen CL1, Chyu MC, Yeh JK, Zhang Y, Pence BC, Felton CK, Brismée JM, Arjmandi BH, Doctolero S, Wang JS. (PubMed)

#Coffee and Coffee Caffeine inversely Are Asscoiated with a Reduced Risk of Cancers But Esophageal Cancer, Researchers Suggest

Kyle J. Norton

Intake of coffee regularly may have a profound effect on the reduced risk of cancers, a recent study proposed.
Cancer is a group of diseases characterized by irregular cell growth in any tissue and organ in the body.

Coffee, becoming a popular and social beverage all over the world, particularly in the West, is a drink made from roast beans from the Coffea plant, native to tropical Africa and Madagascar.

According to the joint study led by the Università Degli Studi di Milano-Bicocca, the consumption of healthy foods, particularly coffee rich in polyphenols might have a substantial influence on reduced prevalence of cancer incidence.

Coffee extract with high chlorogenic acids (CGAs) exhibited beneficial biological effects in the ameliorated risk of cancer through anti-inflammatory activity and anti-carcinogenic activity.

In Ras-dependent breast cancer cell line MDA-MB-231, CGAs also displayed a molecular basis of the activity and chemoprotective in the induction of cell apoptosis.


Furthermore, in the review of literature in the expression of the association between total, caffeinated, and decaffeinated coffee consumption and melanoma risk in a dose-response meta-analysis on prospective cohort studies by searching the database of PubMed and Embase, researchers indicated, seven studies eligible for meta-analysis, comprised 1,418,779 participants and 9211 melanoma cases. caffeine attenuated melanoma risk with a linear dose-response association between total coffee consumption.

Prevalence risk of melanoma is reduced by 3% for an additional cup of coffee intake per day.Dr. Micek A, the lead author said, "Coffee intake may be inversely associated with the incidence of melanoma".


In further demonstrated coffee and coffee caffeine in the ameliorated risk of cancer, the Cox proportional hazards regression was used to estimate multivariable-adjusted hazard ratios (HR) for coffee consumption associated with death from all cancers combined and from specific cancer types among 922,896 Cancer with 1982 as a baseline, researchers at joint study lead by the American Cancer Society found that only smokers showed a non-linear association between coffee consumption and all-cancer death but not in never smokers.

Among non-smokers, drinking 2 cups/day or more showed a significant inverse associated with death from colorectal, head and neck, and female breast cancers, but positively associated with esophageal cancer death.

Taken together, coffee and coffee caffeine have profound effects in reducing the risk of many types of cancer, except esophageal cancer which may be attributed to the long-term themo effect of hot beverage intake.


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Sources
(1) Natural Compounds in Cancer Prevention: Effects of Coffee Extracts and Their Main Polyphenolic Component, 5-O-Caffeoylquinic Acid, on Oncogenic Ras Proteins by Palmioli A1, Ciaramelli C1, Tisi R1,2, Spinelli M1, De Sanctis G1, Sacco E1,3, Airoldi C1,2,3.(PubMed)
(2) Caffeinated and decaffeinated coffee consumption and melanoma risk: a dose-response meta-analysis of prospective cohort studies by Micek A1, Godos J2, Lafranconi A3, Marranzano M2, Pajak A1.(PubMed)
(3) Associations of Coffee Drinking and Cancer Mortality in the Cancer Prevention Study-II by Gapstur SM1, Anderson RL2, Campbell PT2, Jacobs EJ2, Hartman TJ3, Hildebrand JS4, Wang Y2, McCullough ML2.(PubMed)

#Herbal #oltsfoot Inhibits Parameters Associated with Convalescent Stage in the Treatment of Asthma, Researchers Show

Kyle J. Norton

Respiratory disease is a medical condition that affects the breathing organs and tissues including Inflammatory lung disease, obstructive lung diseases, restrictive lung diseases, respiratory tract infections, trachea, bronchi, bronchioles, alveoli, nerves, and muscle breathing,...
The most common symptom of respiratory disease is shortness of breath.

The lungs formed part of the respiratory symptoms, are a pair of spongy, air-filled organs located on either side of the chest (thorax). The organ plays a critical role in inhaling oxygen to the body and exhaling carbon dioxide from the body.

Asthma is a medical and chronic condition characterized by the long-term inflammation of the airways of the lungs.

The most common symptoms of asthma are episodes of wheezing, coughing, chest tightness, shortness of breath, reversible airflow obstruction, and bronchospasm.

Asthma attack in most cases is triggered by exposure to various irritants and substances that trigger allergies (allergens). However, genetic preposition and family history are also found in patients with asthma.

Asthma not only interferes with daily activities and also can lead to a life-threatening asthma attack. Treatment of asthma is to reduce the frequent episodes and severity of the attacks.

According to the statistics provided by the Centers for Disease Control and Prevention (CDC), in the US, 1 in 13 people have asthma. In other words, over 26 million Americans have asthma and half of that is children.

Believe it or not, African Americans in the U.S. die from asthma at a higher rate than people of other races or ethnicities.

Dr. Laurent Guilleminault, in the environmental effect in the risk asthma, said, "The rates of asthma and allergy (Type 1 hypersensitivity disorders) have been increasing worldwide for the last few decades. Various theories have been proposed to account for this alarming trend. One of these is the impact of environmental toxicants".


And, "depletion of glutathione levels (with oral supplementation of N-acetylcysteine), and enhancement of glutathione transferase function (using sulforaphane) might be therapeutic options for countering type 1 hypersensitivity disorders caused by environmental chemicals".

In other words, environmental toxins cause reduced levels of antioxidants in the body and are associated with the risk of asthma onset

Coltsfoot(Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belonging to the family Asteraceae, native to Europe and Asia. The herb has been used for thousands of years to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches obstruction in the nasal passage, etc.

In finding a potential compound for the treatment of respiratory disease, researchers examined the effect of invigorating Kidney (Viscum coloratum 15g, Psoralea corylifolia 15g, Eucommia ulmoides 15g, Lycium chinense 9g, Tussilago farfara 15g, Artemisia capillaris 9g, and Pogostemon cablin 9g as daily dosage) on asthma by measuring maximal expiratory flow-volume curve (MEFV) in the convalescent stage.

In a total of 66 cases of asthmatics were examined, researchers found that before treatment by the invigorating Kidney decoction, the results of FEV, PEF, V75, V50, and V25 in 35 cases or 53.03% of the total demonstrated a significantly negative effect compared with healthy persons.

In other words, in the convalescent stage, convalescent stage, over half of the asthmatics showed obstruction of airways and chiefly of small airways.

According to the tested analysis after treatment of the decoction only exerted effects on different parameters associated with the improvement of MEFV to some extent, but also reversed the airway obstruction of asthmatics in the convalescent stage.

Based on the findings, researchers said, "the authors indicated that the prompt treatment for asthmatics in the convalescent stage was conducive early to prevent emphysema and confirmed that the treatment with Chinese herbs of chiefly invigorating Kidney deserved to be propagated.".

Taken together, coltsfoot used alone and combined with other herbal medicines may be considered a remedy for the treatment of asthmatics in the convalescent stage, pending the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) [Measurement of MEFV in 66 cases of asthma in the convalescent stage and after treatment with Chinese herbs].[Article in Chinese] by Fu JX. (PubMed)
(2) Do environmental toxicants contribute to allergy and asthma? by Crinnion WJ. (PubMed)

Saturday, 30 September 2023

#Herbal #Angelica Sinensis Inhibits Parameters Associated with #WeightControl in #Obesity, Researchers Find

Kyle J. Norton

Obesity is a medical condition caused by excess body fat accumulated to some extent that impacts personal health. The hallmark of obesity is attenuated metabolism and structural cell changes in the obese fat observed by reducing metabolic activity.

According to the Body Mass Index(BMI), people who have a BMI between 25 to 29.9 are considered overweight and a BMI of over 30 is an indication of obesity.

The formula of the BMI indexBMI= weight (kg)/ height (m2)

According to the statistics, 68% of the American population is either overweight or obese. However,
in 2016, more than 1.9 billion adults, 18 years and older, were overweight, including over 650 million who were obese worldwide.

Visceral fat obesity is associated with 90% of patients with ischemic heart disease. In obese, the accumulation of visceral fat is predominant in the intra-abdominal cavity.

Visceral fat is a layer of fat that surrounds the organs. Overexpression of visceral fat has been found to promote insulin resistance, diabetes, heart disease, and inflammation.

However, in non-obese subjects, visceral fat accumulation is correlated with glucose intolerance, hyperlipidemia, and hypertension.

Obesity rates have increased for all age groups in the US over the last several decades, coincidently with the periods that promoted the Western diet.

Weight gain is an increase in body weight associated with some parameters, including increased muscle mass, fat deposits, excess fluids such as water, or other factors.


However, weight gain has also been found to be induced by serious medical conditions.

In finding a natural ingredient for the prevention and treatment of obesity, scientists examined the radix Angelica sinensis (RAS) suppressed body weight by altering the expression of the fat mass and obesity-associated (FTO) gene in an animal model.

Angelica or Dang Gui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.

The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen the heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.

According to tested analysis in mice fed with high-fat diet (HFD)-induced obesity,
* 36 differentially expressed genes (DEGs) associated with the increased onset of obesity were found in adipose tissues from the RAS supplementation group (DH) and control group (HC).


* Six out of the 36 DEGs identified to be involved in lipid metabolism, with the APOA2 gene a potential anti-obesogenic influence were inhibited by the injection of RAS compared to control.

In other words, RAS supplementation in HFD-induced obese mice was associated with an anti-obesogenic global transcriptomic response.

Based on the results, researchers suggest, "This study provides insight into potential applications of RAS in obesity therapy".


Taken together, Dandelion may be considered a remedy for the treatment of weight gain in obese, pending the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Anti-obesity effect of radix Angelica sinensis and candidate causative genes in transcriptome analyses of adipose tissues in high-fat diet-induced mice by Zhong T1, Zhang H1, Duan X1, Hu J1, Wang L1, Li L1, Zhang H1, Niu L. (PubMed)

#Coffee Reduces the Serum Uric Acid Level Depending on Gender and Number of Cup Intake Daily and Regularly, Scientists Show

Kyle J. Norton

Good News for coffee lovers, intake of coffee is associated with ameliorated levels of uric acid, a marker of gout incidence, a renowned institute study suggested.

However, intake of foods with high amounts of purines may cause an excess of uric acid in your blood.

According to the observation of data from 14,758 participants ages >/=20 years in the Third National Health and Nutrition Examination Survey (1988-1994), decreased serum uric acid level is associated with increased coffee intake.

Serum uric acid level was significantly lower with coffee intake of 4 to 5 and >/=6 cups daily compared to non-drinkers.


The study also indicated that serum uric acid was not affected by total caffeine from coffee and other beverages.

Additionally, researchers in the review of databases of MEDLINE, EMBASE, the Cochrane Library, and KoreaMed for all articles published before January 2015, 9 studies published between 1999 and 2014, containing a total of 175,310 subjects, demonstrated that coffee has a significantly lowering effect on serum UA.

The amount of coffee required to lower serum UA is different by gender. Women are required to consumse more cups of coffee (4-6 cups/day) compared to their male counterparts (1-3 cups/day) to exhibit the same effects

Significantly, the incidence of gout was even reduced linearly in participants with the intake of 1 cup/day or more with no different in both genders.

Promisingly, in a total of 11.662 men and women aged 49-76 years, excluding those with medication for gout and hyperuricemia, use of diuretic drugs, and medical care for cancer or chronic kidney disease, daily consumption of coffee has significantly inverse associations with serum UA concentrations in men.

Compared to women participants, male participants expressed a statistically significant elevation of an inverse association between coffee and serum UA levels.

Taken together, the intake of coffee is associated with a reduced level of serum uric acid in the blood depending on the number of cups intake per day.


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca


Biography
Kyle J. Norton(Scholar, Master of Nutrients), all rights reserved.
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, healthblogs, selfgrowth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio science, ISSN 0975-6299.


Sources
(1) Coffee, tea, and caffeine consumption and serum uric acid level: the third national health and nutrition examination survey by Choi HK1, Curhan G.(PubMed)
(2) Effects of coffee consumption on serum uric acid: systematic review and meta-analysis by Park KY1, Kim HJ2, Ahn HS2, Kim SH1, Park EJ1, Yim SY3, Jun JB4.(PubMed)
(3) The relation of coffee consumption to serum uric Acid in Japanese men and women aged 49-76 years by Pham NM1, Yoshida D, Morita M, Yin G, Toyomura K, Ohnaka K, Takayanagi R, Kono S.(PubMed)

#ChasteTreeBerry Fruit #Extract Processes Anti-Androgenic Effect Against Male Sexual Libido, Acne and Prostate Disease, Researchers Say

Kyle J. Norton

A recent study conducted by a renowned institute suggested that Vitex agnus castus (Vac.) may have the potential to decrease the overproduction of testosterone in male reproductive physiology.

Testosterone is a male steroid hormone that plays an important role in male reproductive organs and building bone and muscle mass as well as stimulating sexual desire in both sexes.

Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as an aphrodisiac herb and considered a Queen herb in treating menstrual problems and discomforts.

In the study of hydroalcoholic Vac. extract (extraction by percolation technique) with the following doses: 65, 165, 265, 365, and 465 mg kg-', bromocriptine as a dopamine receptor agonist (5, 10, 20 mg kg(-1)) and haloperidol as a dopamine receptor antagonist (1, 1.5, 2, 2.5, 3 mg kg(-1)) injection male mice treated with chaste tree berry extract or combination of the extract showed a significant decrease of levels of testosterone in compared to other treatment groups.

Dr. Nasri S, the lead author said, ". LH and testosterone were measured by Radio Immuno Assay (RIA). LH and testosterone showed a significant decrease in the bromocriptine group and haloperidol increased these hormones. Vac. extract decreased significantly the LH and testosterone levels. The coadministration of Vac. extract and bromocriptine decreased LH and testosterone".

The study also found that Vitex agnus castus extract influences neurotransmitters such as dopamine in regulated LH and testosterone secretion.

In confirming the efficacy of chaste tree berry in reduced testosterone production, Vitex agnus castus L. (Vit.) fruit extract with 1650 mg/kg was tested on male mice models with the doses (65, 165, 265, 365, 465 mg/kg) injected intraperitoneally for 30 days in 5 groups of animals, all tested mice showed a decreased testosterone levels in dose depending manner.

The researchers also insisted that through the Radio Immuno Assay (RIA), Vit. the fruit extract has an anti-androgenic effect and probably acts through the Hypothalamic-Pituitary-Gonadal (HPG) axis and the side effects only appear after a long time of their usage.

Dr Jillian Stansbury, not the author of the studies said, " (due to the effects of chaste tree berry in reduced LH levels and testosterone levels ) that Vitex may improve symptoms of high testosterone levels in men, including excessive libido, acne, and prostatic disease."

The reduced levels of testosterone in herbal medicine may be beneficial for patients with high levels of testosterone-induced sexual libido, acne, and abnormal prostate expression.


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months



Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10,000 articles and research papers have been written and published on line, including worldwide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.

Sources
(1) The effects of Vitex agnus castus extract and its interaction with dopaminergic system on LH and testosterone in male mice by Nasri S1, Oryan S, Rohani AH, Amin GR.(PubMed)
(2) The Effects of Vitex agnus castus L. Extract on Gonadotrophines and Testosterone in Male Mice(Researchgate)
(3) WOMEN’S HERBS” FOR MEN By Editor1 Posted November 8, 2010
In Botanical Medicine, Endocrinology, Fertility, Men's Health, Nature Cure, Oncology, Dr Jillian Stansbury