Kyle J. Norton
Cystic fibrosis (CF) is a genetic preposition that leads to diseases mostly in the lungs in children and young adults.
Most cases of CF have been found to cause persistent infection in the lungs, leading to the destruction of lung tissues and reduced lung function, depending on the severity of the condition.
The most common complication of CF is difficulty digesting fats, proteins, and nutrient absorption, progressive lung damage caused by ongoing infections chronic low-grade inflammation, and CF-related diabetes.
According to statistics provided by the Canadian Cystic Fibrosis Foundation, approximately 1 in every 3,600 children born in Canada has CF.
In age perspective,
* 60% of patients are diagnosed in the first year of life, and 90% by 10 years of age.
* More than 47% of all Canadians with CF are over the age of 18 years.
* As of 2002, the median age of survival of Canadians with CF is 37 years of age.
The most common symptoms of CF are persistent cough with productive thick mucous, wheezing and shortness of breath, frequent chest infections, weight loss or failure to gain weight, infertility in men, and decreased fertility in women.
Conventionally, as of today, there is no cure for CF. Medications are focusing on reducing symptoms and improving quality of life, including
* Antibiotics for the treatment of lung infections.
* Anti-inflammatory medications to protect the lung airways.
* Medication to reduce cough up the mucus
* Inhaled medications to keep your airways open by relaxing the muscles around your bronchial tubes
* Medication to help the digestive tract in absorbing nutrients
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
In finding a natural compound for the treatment of cystic fibrosis, researchers compared identical capsules half-filled with mini-tablets of a new high lipase preparation in a randomized double-blind crossover study in children with cystic fibrosis.
All children who participated in the study received his/her usual number of capsules and the same dose of lipase during each period of the study.
According to the results from the 18 children who completed the study, the pancreatic enzyme applied in the high lipase preparation showed fewer gastrointestinal symptoms compared to the low lipase group.
Compared to the baseline, the pancreatic enzyme group showed a significant improvement in fat absorption and a reduction in fecal fat output.
Fecal energy loss was also improved in the treatment group.
Based on the findings, researchers at the St James's Hospital wrote, " (The) half-filled capsules of the new high lipase preparation are more effective than the standard preparation and it is likely that filled capsules would allow patients to use fewer than half the number of pancreatic enzyme capsules".
Taken together, bromelain may be considered a supplement for the prevention and treatment of symptoms of cystic fibrosis, pending the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Gut inflammation in children with cystic fibrosis on high-dose enzyme supplements by Croft NM1, Marshall TG, Ferguson A. (PubMed)
(2) A double-blind lipase for lipase comparison of a high lipase and standard pancreatic enzyme preparation in cystic fibrosis by Bowler IM1, Wolfe SP, Owens HM, Sheldon TA, Littlewood JM, Walters MP. (PubMed)
Wednesday, 27 September 2023
Tuesday, 26 September 2023
#Capsicum Frutescens (#Cayenne)Inhibit Symptoms and Improve Quality of Life of Unspecific #LowBackPain, According to Studies
Kyle J. Norton
Low back pain is a musculoskeletal disorder (MSD) of degenerative disc disease, with pain persisting for longer than 3 months, affecting over 80% of the population in the US alone at some point in their life.
Chronic LBP prevalence in older adults was significantly higher than the 21-to-44-year age group and inflicted more disabled, longer symptom duration, etc.(2). The unique impact of CLBP is unknown(3).
Acute lower back pain is a common musculoskeletal disorder (MSD) caused by injury to the muscles, ligaments, joints, or discs that last less than a few months.
Chronic lower back pain that lasts longer than 6 months, is normally caused by damage to nerves in the lower back which supplies sensation and power to the muscles in the pelvis, legs, and feet.
According to the statistics, up to 80% of the population will experience back pain at some time in their lives. The condition affects people of all ages, particularly in occupations requiring the use of muscles of the lower back.
Worldwide, years lived with a disability caused by low back pain have increased by 54% between 1990 and 2015.
Depending on the severity of the condition, chronic lower back pain can induce symptoms of numbness, tingling, or weakness in one or both legs and intense, constant pain that gets worse at night.
Some people with chronic lower back pain may also experience symptoms of loss of bowel or bladder control and unexplained weight loss.
According to the statistics, the lifetime prevalence of non-specific (common) low back pain is estimated at 60% to 70% in industrialized countries with a one-year prevalent rate ranging from 15% to 45%. The adult incidence of lower back pain is 5% per year.
Comfrey is a perennial plant in the genus of Symphytum, belonging to the family Boraginaceae, native to Europe. It has been used in herbal and traditional medicine to ease excessive bleeding or on open wounds, relieve pain and swelling, treat circulation issues, reduce cholesterol, etc.
In finding a potential compound for the treatment of diseases associated with neuro and muscle pain, researchers examined the effectiveness of herbal medicine, including comfrey for nonspecific low back pain (LBP).
A systematic review of randomized controlled trials (RCTs) involved in the searching of studies published on numerous electronic databases up to September 2014 found 14 RCTs with 2050 participants/
Capsicum frutescens (cayenne) reduces pain more than placebo.
Although Harpagophytum procumbens (devil's claw), Salix alba (white willow bark), Symphytum officinale L. (comfrey), Solidago chilensis (Brazilian arnica), and Lavender essential oil also seem to reduce pain more than placebo, evidence for these substances was of moderate quality at best.
All tested herbal medicines showed no significant adverse events within the included trials.
Taken altogether, Comfrey and other herbal medicines may be considered a remedy for the treatment of unspecific low back pain, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Herbal Medicine for Low Back Pain: A Cochrane Review by Gagnier JJ1, Oltean H, van Tulder MW, Berman BM, Bombardier C, Robbins CB. (PubMed)
(2) Herbal medicine for low-back pain by Oltean H1, Robbins C, van Tulder MW, Berman BM, Bombardier C, Gagnier JJ. (PubMed)
Low back pain is a musculoskeletal disorder (MSD) of degenerative disc disease, with pain persisting for longer than 3 months, affecting over 80% of the population in the US alone at some point in their life.
Chronic LBP prevalence in older adults was significantly higher than the 21-to-44-year age group and inflicted more disabled, longer symptom duration, etc.(2). The unique impact of CLBP is unknown(3).
Acute lower back pain is a common musculoskeletal disorder (MSD) caused by injury to the muscles, ligaments, joints, or discs that last less than a few months.
Chronic lower back pain that lasts longer than 6 months, is normally caused by damage to nerves in the lower back which supplies sensation and power to the muscles in the pelvis, legs, and feet.
According to the statistics, up to 80% of the population will experience back pain at some time in their lives. The condition affects people of all ages, particularly in occupations requiring the use of muscles of the lower back.
Worldwide, years lived with a disability caused by low back pain have increased by 54% between 1990 and 2015.
Depending on the severity of the condition, chronic lower back pain can induce symptoms of numbness, tingling, or weakness in one or both legs and intense, constant pain that gets worse at night.
Some people with chronic lower back pain may also experience symptoms of loss of bowel or bladder control and unexplained weight loss.
According to the statistics, the lifetime prevalence of non-specific (common) low back pain is estimated at 60% to 70% in industrialized countries with a one-year prevalent rate ranging from 15% to 45%. The adult incidence of lower back pain is 5% per year.
Comfrey is a perennial plant in the genus of Symphytum, belonging to the family Boraginaceae, native to Europe. It has been used in herbal and traditional medicine to ease excessive bleeding or on open wounds, relieve pain and swelling, treat circulation issues, reduce cholesterol, etc.
In finding a potential compound for the treatment of diseases associated with neuro and muscle pain, researchers examined the effectiveness of herbal medicine, including comfrey for nonspecific low back pain (LBP).
A systematic review of randomized controlled trials (RCTs) involved in the searching of studies published on numerous electronic databases up to September 2014 found 14 RCTs with 2050 participants/
Capsicum frutescens (cayenne) reduces pain more than placebo.
Although Harpagophytum procumbens (devil's claw), Salix alba (white willow bark), Symphytum officinale L. (comfrey), Solidago chilensis (Brazilian arnica), and Lavender essential oil also seem to reduce pain more than placebo, evidence for these substances was of moderate quality at best.
All tested herbal medicines showed no significant adverse events within the included trials.
Taken altogether, Comfrey and other herbal medicines may be considered a remedy for the treatment of unspecific low back pain, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Herbal Medicine for Low Back Pain: A Cochrane Review by Gagnier JJ1, Oltean H, van Tulder MW, Berman BM, Bombardier C, Robbins CB. (PubMed)
(2) Herbal medicine for low-back pain by Oltean H1, Robbins C, van Tulder MW, Berman BM, Bombardier C, Gagnier JJ. (PubMed)
#Healthy Food #Broccoli's #Sulforaphane (SFN) Inhibits #DiabeticCardiomyopathy by Decreasing Cardiac Lipid Accumulation in Diabetes, Researchers Say
Kyle J. Norton
Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate the glucose.
In other words, diabetes occurs when cells in the pancreas die off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.
Diabetic complications are any diseases associated with hyperglycemia if the blood glucose is not managed properly. Patients with diabetes may experience a number of complications including cardiovascular disease, neuropathy, nephropathy, retinopathy, and foot ulcers.
Cardiomyopathy is a disease associated with heart muscle, leading to reduced functions of the heart to pump blood to the rest of the body.
Diabetic cardiomyopathy is a complication found in patients with diabetes associated with reducing the heart function in circulating blood through the body, leading to heart failure and increased accumulation of fluid in the lungs.
Diabetic cardiomyopathy is classified into different types, depending on the damage that has been affected, including
* Microangiopathy is a disorder that affects small blood vessels, leading to impaired myocardial blood flow reserve.
* Autonomic neuropathy is a disorder that affects the nerves that manage everyday body functions, leading to abnormal blood pressure, heart rate.
* Endothelial dysfunction is a disorder associated with the damage of vascular endothelium. The condition is considered an early event of cardiovascular disease.
The most common causes of diabetic cardiomyopathy are myocardial dysfunction in the absence of overt clinical coronary artery disease, valvular disease, and other conventional cardiovascular risk factors, such as hypertension and dyslipidemia.
Broccoli is a mustard/cabbage plant, belonging to the family Brassicaceae. The veggie has large flower heads, usually green in color with a mass of flower heads surrounded by leaves and evolved from a wild cabbage plant from the continent of Europe.
With an aim to find a natural food for the prevention and treatment of diabetic complications, researchers examined the effect of sulforaphane (SFN) on T2DM-induced cardiac lipid accumulation and subsequent cardiomyopathy.
The study included male C57BL/6J mice fed a high-fat diet for 3months to induce insulin resistance, followed by treatment with 100mg/kg body-weight streptozotocin to induce hyperglycemia as the T2DM mouse model compared to age-matched mice fed a normal diet as control.
According to the tested analysis,
* SFN treatment significantly attenuated cardiac remodeling and dysfunction induced by T2DM.
* SFN treatment also significantly inhibited cardiac lipid accumulation, measured by Oil Red O staining, and improved cardiac inflammation oxidative stress and fibrosis, shown by down-regulating diabetes-induced PAI-1, TNF-α, CTGF, TGF-β, 3-NT, and 4-HNE expression involved in oxidation.
* SFN upregulated the expression of the gene associated with the promotion of antioxidant enzyme and decreased the expression in enhancing the initiation of oxidative stress.
* SFN also reversed diabetes-induced inhibition of LKB1/AMPK and its downstream targets associated with the regulation of lipid, cholesterol and glucose metabolism.
Based on the results, researchers wrote, " SFN treatment to T2DM mice may attenuate the cardiac oxidative stress-induced inhibition of LKB1/AMPK signaling pathway, thereby preventing T2DM-induced lipotoxicity and cardiomyopathy".
Taken altogether, broccoli processed abundantly SFN may be considered supplements for the prevention of diabetic cardiomyopathy, pending to the confirmation of the larger sample size and multicenter human study.
Intake of SFN in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Sulforaphane prevents the development of cardiomyopathy in type 2 diabetic mice probably by reversing oxidative stress-induced inhibition of LKB1/AMPK pathway by Zhang Z1, Wang S1, Zhou S1, Yan X2, Wang Y1, Chen J3, Mellen N3, Kong M4, Gu J5, Tan Y2, Zheng Y6, Cai L. (PubMed)
Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate the glucose.
In other words, diabetes occurs when cells in the pancreas die off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.
Diabetic complications are any diseases associated with hyperglycemia if the blood glucose is not managed properly. Patients with diabetes may experience a number of complications including cardiovascular disease, neuropathy, nephropathy, retinopathy, and foot ulcers.
Cardiomyopathy is a disease associated with heart muscle, leading to reduced functions of the heart to pump blood to the rest of the body.
Diabetic cardiomyopathy is a complication found in patients with diabetes associated with reducing the heart function in circulating blood through the body, leading to heart failure and increased accumulation of fluid in the lungs.
Diabetic cardiomyopathy is classified into different types, depending on the damage that has been affected, including
* Microangiopathy is a disorder that affects small blood vessels, leading to impaired myocardial blood flow reserve.
* Autonomic neuropathy is a disorder that affects the nerves that manage everyday body functions, leading to abnormal blood pressure, heart rate.
* Endothelial dysfunction is a disorder associated with the damage of vascular endothelium. The condition is considered an early event of cardiovascular disease.
The most common causes of diabetic cardiomyopathy are myocardial dysfunction in the absence of overt clinical coronary artery disease, valvular disease, and other conventional cardiovascular risk factors, such as hypertension and dyslipidemia.
Broccoli is a mustard/cabbage plant, belonging to the family Brassicaceae. The veggie has large flower heads, usually green in color with a mass of flower heads surrounded by leaves and evolved from a wild cabbage plant from the continent of Europe.
With an aim to find a natural food for the prevention and treatment of diabetic complications, researchers examined the effect of sulforaphane (SFN) on T2DM-induced cardiac lipid accumulation and subsequent cardiomyopathy.
The study included male C57BL/6J mice fed a high-fat diet for 3months to induce insulin resistance, followed by treatment with 100mg/kg body-weight streptozotocin to induce hyperglycemia as the T2DM mouse model compared to age-matched mice fed a normal diet as control.
According to the tested analysis,
* SFN treatment significantly attenuated cardiac remodeling and dysfunction induced by T2DM.
* SFN treatment also significantly inhibited cardiac lipid accumulation, measured by Oil Red O staining, and improved cardiac inflammation oxidative stress and fibrosis, shown by down-regulating diabetes-induced PAI-1, TNF-α, CTGF, TGF-β, 3-NT, and 4-HNE expression involved in oxidation.
* SFN upregulated the expression of the gene associated with the promotion of antioxidant enzyme and decreased the expression in enhancing the initiation of oxidative stress.
* SFN also reversed diabetes-induced inhibition of LKB1/AMPK and its downstream targets associated with the regulation of lipid, cholesterol and glucose metabolism.
Based on the results, researchers wrote, " SFN treatment to T2DM mice may attenuate the cardiac oxidative stress-induced inhibition of LKB1/AMPK signaling pathway, thereby preventing T2DM-induced lipotoxicity and cardiomyopathy".
Taken altogether, broccoli processed abundantly SFN may be considered supplements for the prevention of diabetic cardiomyopathy, pending to the confirmation of the larger sample size and multicenter human study.
Intake of SFN in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Sulforaphane prevents the development of cardiomyopathy in type 2 diabetic mice probably by reversing oxidative stress-induced inhibition of LKB1/AMPK pathway by Zhang Z1, Wang S1, Zhou S1, Yan X2, Wang Y1, Chen J3, Mellen N3, Kong M4, Gu J5, Tan Y2, Zheng Y6, Cai L. (PubMed)
#CruciferousVegetables Reduce the Risk of #ColonCancer by Decreasing Aberrant Crypt Foci (ACF), Cialomucin-Producing Foci, or Mucin-Depleted Foci (MDF) Numbers
Kyle J. Norton
The colon forms part of the digestive system including a large intestine that connects to the small intestines and the rectum plays a critical role in reabsorbing fluids processing waste products from the body and preparing for their elimination through the rectum.
Colon cancer is relatively very common and slowly growing and progresses cancer in a predictable way. The disease is the third most commonly diagnosed cancer in developed countries, including the US and Canada.
Most cases of primary colon cancer start in the cells on the surface of the inner lining of the colon. At the early stage. most patients with colon cancer do not experience any symptoms.
However, at the advanced stage, the tumor not only can spread to other healthy tissue and organs a distance away through blood and fluid circulation but also suppress the nearby tissue and nerve cells.
The progression of colon cancer at this stage not only induces symptoms of the change in bowel habits, the change in the consistency of your stool, that lasts longer than four weeks but also causes rectal bleeding and persistent abdominal severe pain.
According to the statistics by the American Cancer Society, in the US, there are
97,220 new cases of colon cancer were diagnosed in 2018. The lifetime risk of developing colorectal cancer is 1 in 22 (4.49%) for men and 1 in 24 (4.15%) for women.
The 5-year survival rate for patients diagnosed with localized stage colorectal cancer is 90%. About 39% of patients are diagnosed at this early stage.
Researchers do not know the exact causes of the disease. However, they do know a history of polyps, ethnicity, a high-fat diet, and low fiber, an increase in age, and the long-term infection of colon diseases are some of the prevalent factors associated with the onset and progression of colon cancer.
Cruciferous vegetables are a group of vegetables, belongings to the family Brassicaceae (also called Cruciferae) with many genera, and species, and cultivated all over the world in suitable climates for commercial profits, including cauliflower, cabbage, kale, garden cress, bok choy, broccoli, Brussels sprouts, and green leafy vegetables.
On finding a potential compound for the treatment of cancers, researchers examined the effects of diets containing cruciferous vegetables on colon cancer risk.
According to the experiments of* Expt. 1, with rats that were fed a vegetable-free (basal) diet or diets containing different lyophilized cruciferous vegetables in concentrations between 4 and 10%.
* Expt. 2, rats that were fed the basal diet or diets containing 10-22.6% fresh cruciferous vegetables. Diets were fed for 2 wk (Expt. 1) or 3 wk (Expt. 2) before and 7 wk (Expt. 1) or 12 wk (Expt. 2) after administration of the colon carcinogen 1,2-dimethylhydrazine.
Moreover, rats fed fresh vegetables were also injected with a low dose of carcinogen 18-24 h prior to termination.
According to the dietary information,
* Groups fed lyophilized vegetables did not differ in aberrant crypt foci (ACF), sialomucin-producing foci, or mucin-depleted foci (MDF) numbers.
Furthermore, all fresh vegetable diets significantly decreased ACF (approximately 40%) and MDF numbers, and the activities of the hepatic phase I enzyme CYP2E1 involved in drugs and alcohol metabolism did not differ among groups in either experiment.
Additionally, the levels of liver glutathione S-transferase (GST) and quinone reductase activities associated with detoxification did not differ among groups fed fresh vegetables, whereas the lyophilized cabbage diets decreased GST activity, compared with the basal diet.
Taken together, cruciferous vegetables may be considered functional foods for reducing the risk of colon cancer, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cruciferous vegetables reduce morphological markers of colon cancer risk in dimethylhydrazine-treated rats by Arikawa AY1, Gallaher DD. (PubMed)
The colon forms part of the digestive system including a large intestine that connects to the small intestines and the rectum plays a critical role in reabsorbing fluids processing waste products from the body and preparing for their elimination through the rectum.
Colon cancer is relatively very common and slowly growing and progresses cancer in a predictable way. The disease is the third most commonly diagnosed cancer in developed countries, including the US and Canada.
Most cases of primary colon cancer start in the cells on the surface of the inner lining of the colon. At the early stage. most patients with colon cancer do not experience any symptoms.
However, at the advanced stage, the tumor not only can spread to other healthy tissue and organs a distance away through blood and fluid circulation but also suppress the nearby tissue and nerve cells.
The progression of colon cancer at this stage not only induces symptoms of the change in bowel habits, the change in the consistency of your stool, that lasts longer than four weeks but also causes rectal bleeding and persistent abdominal severe pain.
According to the statistics by the American Cancer Society, in the US, there are
97,220 new cases of colon cancer were diagnosed in 2018. The lifetime risk of developing colorectal cancer is 1 in 22 (4.49%) for men and 1 in 24 (4.15%) for women.
The 5-year survival rate for patients diagnosed with localized stage colorectal cancer is 90%. About 39% of patients are diagnosed at this early stage.
Researchers do not know the exact causes of the disease. However, they do know a history of polyps, ethnicity, a high-fat diet, and low fiber, an increase in age, and the long-term infection of colon diseases are some of the prevalent factors associated with the onset and progression of colon cancer.
Cruciferous vegetables are a group of vegetables, belongings to the family Brassicaceae (also called Cruciferae) with many genera, and species, and cultivated all over the world in suitable climates for commercial profits, including cauliflower, cabbage, kale, garden cress, bok choy, broccoli, Brussels sprouts, and green leafy vegetables.
On finding a potential compound for the treatment of cancers, researchers examined the effects of diets containing cruciferous vegetables on colon cancer risk.
According to the experiments of* Expt. 1, with rats that were fed a vegetable-free (basal) diet or diets containing different lyophilized cruciferous vegetables in concentrations between 4 and 10%.
* Expt. 2, rats that were fed the basal diet or diets containing 10-22.6% fresh cruciferous vegetables. Diets were fed for 2 wk (Expt. 1) or 3 wk (Expt. 2) before and 7 wk (Expt. 1) or 12 wk (Expt. 2) after administration of the colon carcinogen 1,2-dimethylhydrazine.
Moreover, rats fed fresh vegetables were also injected with a low dose of carcinogen 18-24 h prior to termination.
According to the dietary information,
* Groups fed lyophilized vegetables did not differ in aberrant crypt foci (ACF), sialomucin-producing foci, or mucin-depleted foci (MDF) numbers.
Furthermore, all fresh vegetable diets significantly decreased ACF (approximately 40%) and MDF numbers, and the activities of the hepatic phase I enzyme CYP2E1 involved in drugs and alcohol metabolism did not differ among groups in either experiment.
Additionally, the levels of liver glutathione S-transferase (GST) and quinone reductase activities associated with detoxification did not differ among groups fed fresh vegetables, whereas the lyophilized cabbage diets decreased GST activity, compared with the basal diet.
Taken together, cruciferous vegetables may be considered functional foods for reducing the risk of colon cancer, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cruciferous vegetables reduce morphological markers of colon cancer risk in dimethylhydrazine-treated rats by Arikawa AY1, Gallaher DD. (PubMed)
#Fennel #Exact Inhibits #Hypertension by Lowering Systolic Blood Pressure of SHR, Studies Show
Kyle J. Norton
Fennel may have a potential and positive effect on the improvement of cardiovascular activity, some scientists suggested.
The results of vascular and cardiovascular protective effects were reported by a number of universities including Birzeit University and published in online medical literature.
Fennel (Foeniculum vulgare) is a plant species of genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean, used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...
In the study to investigate the vascular effects of aqueous extracts of Foeniculum vulgare leaves in pentobarbital-anaesthetised rats, researchers found that intravenous administration of the lyophilized boiled water extract exerted a significant dose-related reduction in arterial blood pressure, without affecting the heart rate or respiratory rate in compared to histamine antagonists.
However, the application of non-boiled aqueous extract showed very little hypotensive activity.
In contrast to the conventional medicine histamine antagonists, the hypotensive effect of the boiling water extract appeared not to be mediated by adrenergic, muscarinic, ganglionic, or serotonergic receptors.
Furthermore, in the examination of the cardiovascular effect of the main component of the oil, anethole isolated from tested guinea pig fennel oil in inhibited arachidonic acid, collagen-, ADP- and U46619-induced aggregation, researchers found that application of anethole displayed comparable NO-independent vasorelaxant activity at antiplatelet concentrations.
Anethole also prevented thrombin-induced clot retraction at concentrations similar to fennel oil in comparison of U46619-induced aggregation (IC(50) from 4 to 147 microg ml(-1)). These results were confirmed in tested mice with application F. Vulgare essential oil and anethole in a subacute treatment of 30 mg kg(-1)day(-1) for 5 days.
F. Vulgare essential oil and anethole also showed significant antithrombotic activity in preventing paralysis induced by collagen-epinephrine intravenous injection with 70% and 83% protection, respectively.
In the rat model, both F. Vulgare essential oil and anethole (100 mg kg(-1) oral administration) provided significant protection against ethanol-induced gastric lesions.
After taking into account other co and confounders, together with the collected information Dr. Tognolini M, the lead author said, " F. vulgare essential oil, and its main component anethole, a safe antithrombotic activity that seems due to their broad spectrum antiplatelet activity, clot destabilizing effect, and vasorelaxant action".
Further to reassess other cardiovascular activity of Foeniculum vulgare L, researchers at the UFR Physiologie-Pharmacologie, launched an investigation to compare the effects of Marrubium vulgare L. and Foeniculum vulgare L. in spontaneously hypertensive rats (SHR).
Interestingly, the oral application of Foeniculum extract exerted lowered the systolic blood pressure of SHR without induced change of normotensive Wistar-Kyoto rats (WKY).
These results were probably associated with to function of Foeniculum in increased water, sodium, and potassium excretion.
More importantly, Foeniculum extract hypertensive efficacy was decreased substantially in rats and mice presented with N-nitro-L-arginine.
The results indicated that fennel demonstrated vascular protective activity as a diuretic and a natriuretic.
Taken together, Fennel and its essential oil and bioactive compound anethole may be considered as a function substance in promoting cardiovascular and vascular activity, particularly in animal models with a high risk of cardiovascular disease.
Intake of fennel extract should be taken with extreme care as overdoses may induce liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, healthblogs, selfgrowth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.
Sources
(1) Protective effect of Foeniculum vulgare essential oil and anethole in an experimental model of thrombosis by Tognolini M1, Ballabeni V, Bertoni S, Bruni R, Impicciatore M, Barocelli E.(PubMed)
(2) Pharmacological evidence of hypotensive activity of Marrubium vulgare and Foeniculum vulgare in spontaneously hypertensive rat by El Bardai S1, Lyoussi B, Wibo M, Morel N.(PubMed)
(3) The vascular action of aqueous extracts of Foeniculum vulgare leaves by Abdul-Ghani AS1, Amin R.(PubMed)
Fennel may have a potential and positive effect on the improvement of cardiovascular activity, some scientists suggested.
The results of vascular and cardiovascular protective effects were reported by a number of universities including Birzeit University and published in online medical literature.
Fennel (Foeniculum vulgare) is a plant species of genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean, used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...
In the study to investigate the vascular effects of aqueous extracts of Foeniculum vulgare leaves in pentobarbital-anaesthetised rats, researchers found that intravenous administration of the lyophilized boiled water extract exerted a significant dose-related reduction in arterial blood pressure, without affecting the heart rate or respiratory rate in compared to histamine antagonists.
However, the application of non-boiled aqueous extract showed very little hypotensive activity.
In contrast to the conventional medicine histamine antagonists, the hypotensive effect of the boiling water extract appeared not to be mediated by adrenergic, muscarinic, ganglionic, or serotonergic receptors.
Furthermore, in the examination of the cardiovascular effect of the main component of the oil, anethole isolated from tested guinea pig fennel oil in inhibited arachidonic acid, collagen-, ADP- and U46619-induced aggregation, researchers found that application of anethole displayed comparable NO-independent vasorelaxant activity at antiplatelet concentrations.
Anethole also prevented thrombin-induced clot retraction at concentrations similar to fennel oil in comparison of U46619-induced aggregation (IC(50) from 4 to 147 microg ml(-1)). These results were confirmed in tested mice with application F. Vulgare essential oil and anethole in a subacute treatment of 30 mg kg(-1)day(-1) for 5 days.
F. Vulgare essential oil and anethole also showed significant antithrombotic activity in preventing paralysis induced by collagen-epinephrine intravenous injection with 70% and 83% protection, respectively.
In the rat model, both F. Vulgare essential oil and anethole (100 mg kg(-1) oral administration) provided significant protection against ethanol-induced gastric lesions.
After taking into account other co and confounders, together with the collected information Dr. Tognolini M, the lead author said, " F. vulgare essential oil, and its main component anethole, a safe antithrombotic activity that seems due to their broad spectrum antiplatelet activity, clot destabilizing effect, and vasorelaxant action".
Further to reassess other cardiovascular activity of Foeniculum vulgare L, researchers at the UFR Physiologie-Pharmacologie, launched an investigation to compare the effects of Marrubium vulgare L. and Foeniculum vulgare L. in spontaneously hypertensive rats (SHR).
Interestingly, the oral application of Foeniculum extract exerted lowered the systolic blood pressure of SHR without induced change of normotensive Wistar-Kyoto rats (WKY).
These results were probably associated with to function of Foeniculum in increased water, sodium, and potassium excretion.
More importantly, Foeniculum extract hypertensive efficacy was decreased substantially in rats and mice presented with N-nitro-L-arginine.
The results indicated that fennel demonstrated vascular protective activity as a diuretic and a natriuretic.
Taken together, Fennel and its essential oil and bioactive compound anethole may be considered as a function substance in promoting cardiovascular and vascular activity, particularly in animal models with a high risk of cardiovascular disease.
Intake of fennel extract should be taken with extreme care as overdoses may induce liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, healthblogs, selfgrowth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.
Sources
(1) Protective effect of Foeniculum vulgare essential oil and anethole in an experimental model of thrombosis by Tognolini M1, Ballabeni V, Bertoni S, Bruni R, Impicciatore M, Barocelli E.(PubMed)
(2) Pharmacological evidence of hypotensive activity of Marrubium vulgare and Foeniculum vulgare in spontaneously hypertensive rat by El Bardai S1, Lyoussi B, Wibo M, Morel N.(PubMed)
(3) The vascular action of aqueous extracts of Foeniculum vulgare leaves by Abdul-Ghani AS1, Amin R.(PubMed)
#Lutein and #Zeaxanthin Foound in #Carotenoids Inhibit the Early Onset of Age-Related Macular Degeneration (#AMD), Researchers Say
Kyle J. Norton
Age-related macular degeneration (AMD) is a medical condition that causes slow and progressive vision loss in the central vision found in people over age 60. Over time, AMD may affect the reading as the blurred area increases in size.
In other words, AMD may cause significant visual disability.
Most cases of the early stage of AMD were diagnosed during routine eye health examinations.
At the early stage, age-related macular degeneration is asymptomatic. However, most patients experience symptoms of shadowy areas in their central vision or unusually fuzzy or distorted vision, particularly in seeing wavy or blurred, with some dark areas at the center.
If you have some of the aforementioned symptoms, please check with your doctor to rule out the possibility.
According to statistics, approximately 11 million people in the US have some form of age-related macular degeneration. The risk of getting advanced age-related macular degeneration increases from 2% for those ages 50-59 to nearly 30% for those over the age of 75.
Besides aging, some researchers suggest that other factors such as smoking, family history, gender, race, sun exposure, diet, and obesity also increase the risk of AMD developing.
However, most people with some of the risk factors have never developed AMD.
Dr. Sara Velilla, the lead scientist in the investigation of the risk of smoking on AMD wrote, "Smoking is the most important modifiable risk factor for AMD development and progression".
And, "...smoking by itself promotes molecular and pathological changes that may establish an ideal macular microenvironment for the development of AMD: vascular inflammation and endothelial dysregulation [47–56], oxidative damage [57–80], toxic damage, and histopathological changes [81–87]".
The results strongly suggested, that if you smoke, your risk of age-related macular degeneration is increased by many folds.
Carotenoids are a class of mainly yellow, orange, or red fat-soluble pigments, including lycopene and carotene, found abundantly in ripe tomatoes, pumpkins, carrots, corn, and daffodils.
With an aim to find the potential compound for the prevention and treatment of age-related macular degeneration, researchers evaluated lutein and zeaxanthin (L/Z) are the predominant carotenoids accumulated in the retina of the eye.
Lutein and zeaxanthin (L/Z) have been found to improve and enhance eye health in the general population, particularly in the elderly.
According to the chemical analysis, the effective levels of L/Z achieved through diet alone, with values of 5 mg and 10 mg per day have a strong implication among people at high risk of AMD or with early signs and symptoms of AMD.
In other words, dietary sources of carotenoids can prevent the onset of progression of age-related macular degeneration even with people at a higher risk of AMD.
In order to confirm the effect of lutein and zeaxanthin (L/Z) activity in the protection of AMD, the University of Melbourne. conducted an experiment containing 254 who were identified with early age-related macular degeneration (AMD).
Intakes of L/Z and fatty acids were estimated from food frequency questionnaires.
According to the results, researchers surprisingly found that
* L/Z has a strong implication in reducing the risk of AMD in a dose-dependent manner.
* Increasing L/Z intake was associated with the progression of AMD. Too much of a good thing (L/Z) might be harmful.
After taking other factors into account, researchers wrote, " It is possible that in this study participants adopted a more healthy diet, having been aware of their AMD status at the beginning of the study. This healthy diet was then reflected in the dietary questionnaire completed at the end of the study".
And, " However, this explanation may not adequately explain why those whose AMD had progressed, on the basis of fundus signs and not symptoms such as visual acuity decline, adopted a healthier lifestyle more aggressively than those without progression".
Based on the findings, daily intake of L/Z intake up to 10 mg per day was associated with decreasing the risk of AMD
Taken together, carotenoids processed abundantly L/Z may be considered a remedy for the prevention and treatment of age-related macular degeneration, pending the confirmation of the larger sample size and multicenter human study.
Intake of carotenoids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Lutein and Zeaxanthin-Food Sources, Bioavailability and Dietary Variety in Age-Related Macular Degeneration Protection by Eisenhauer B1, Natoli S2, Liew G3, Flood VM. (PubMed)
(2) Dietary lutein, zeaxanthin, and fats and the progression of age-related macular degeneration by Robman L1, Vu H, Hodge A, Tikellis G, Dimitrov P, McCarty C, Guymer R. (PubMed)
(3) Smoking and Age-Related Macular Degeneration: Review and Update by Sara Velilla, 1, 2 José Javier García-Medina, 3 , 4 , 5 Alfredo García-Layana, 2 , 6Rosa Dolz-Marco, 5 , 7 Sheila Pons-Vázquez, 5 M. Dolores Pinazo-Durán, 2 , 5 , 8Francisco Gómez-Ulla, 2 , 9 , 10 J. Fernando Arévalo, 11 , 12 Manuel Díaz-Llopis, 2 , 7 , 8 andRoberto Gallego-Pinazo. (PMC)
Coffee Exerts A Protective Effect Against the Risk of #Depression, According to Clinical Trials
Kyle J. Norton
Epidemiological studies do not agree that coffee and coffee caffeine have a positive effect on reduced depression, a review literature study suggested.
Coffee, second to green tea, is a popular and social beverage all over the world, particularly in the West, made from roast beans from the Coffea plant, native to tropical Africa and Madagascar.
Depression is a normal neuro response as part of our daily lives such as the loss of s job, the death of a loved one, and illness.
Over 30 million Americans suffer from depression and the amounts are increasing at an alarming rate.
According to the University of Naples Federico II, over 2 decades, many studies addressed the concerns that coffee intake may have an implication of incidence of depression, but several phytochemical studies indicated a different outcome as caffeine and certain major phytoconstituents exhibited antidepressant effects through multiple molecular mechanisms.
Dr. Tenore GC, the lead researcher said, "Coffee can be considered a drink which has different positive effects on human health such as cardioprotective, neuroprotective, hepatoprotective, nephroprotective, etc. However, heavy coffee consumption may be related to some unpleasant symptoms, mainly anxiety, headache, increased blood pressure, nausea, and restlessness".
Contrastively, caffeine in coffee showed a strong inverse association in cases of postpartum depression and comorbid panic disorder.
Other researchers in the search for the efficacy of coffee and the risk of depression through databases from PubMed and PsychINFO insisted that although literature data are conflicting, caffeine found in coffee indicated a significantly reduced effect on symptoms of clinical depression.
Additionally, in a cross-sectional study of 10,177 Korean individuals aged 20-97 years the prevalence of self-reported depression of 14.0%, and of self-reported clinical depression of 3.7%. participated in the fifth Korean National Health and Nutrition Examination Survey. to determine the effect of the consumption of coffee and the risk of depression, after adjusting to other factors, the returned survey from patients can be cataloged into the following
For general depression
1. The relative odd ratio of patients drinking less than one cup/week was 0.84
2. The relative odd ratio of patients drinking one to six cups/week was 0.63
3. The relative odd ratio of patients drinking for one cup/day was 0.69
4. The relative odd ratio of patients drinking for two cups/day was 0.54
5. The relative odd ratio of patients drinking for three or more cups/day was .58
For clinical depression, similar observations also have been recorded
1. The relative odd ratio of patients drinking less than one cup/week was 1.00
2. The relative odd ratio of patients drinking one to six cups/week was 0.51
3. The relative odd ratio of patients drinking for one cup/day was 0.57
4. The relative odd ratio of patients drinking for two cups/day was 0.57
5. The relative odd ratio of patients drinking for three or more cups/day was 0.41
The findings although not linearly, coffee and coffee caffeine intake expressed a protective effect in the ameliorated risk of depression.
Taken together, there is no doubt that coffee and coffee caffeine intake daily and regularly have a profound effect on depression but further cohost large sample-sized studies are necessary to find out other factors that may contribute to either outcome.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, healthblogs, selfgrowth, Best Before it's news, the Karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.
Sources
(1) Coffee and Depression: A Short Review of Literature by Tenore GC1, Daglia M, Orlando V, D'Urso E, Saadat SH, Novellino E, Nabavi SF, Nabavi SM.(PubMed)
(2) [Coffee consumption in depressive disorders: it's not one size fits all].[Article in Italian] by Rusconi AC, Valeriani G, Carluccio GM, Majorana M, Carlone C, Raimondo P, Ripà S, Marino P, Coccanari de Fornari MA, Biondi M.(PubMed)
Epidemiological studies do not agree that coffee and coffee caffeine have a positive effect on reduced depression, a review literature study suggested.
Coffee, second to green tea, is a popular and social beverage all over the world, particularly in the West, made from roast beans from the Coffea plant, native to tropical Africa and Madagascar.
Depression is a normal neuro response as part of our daily lives such as the loss of s job, the death of a loved one, and illness.
Over 30 million Americans suffer from depression and the amounts are increasing at an alarming rate.
According to the University of Naples Federico II, over 2 decades, many studies addressed the concerns that coffee intake may have an implication of incidence of depression, but several phytochemical studies indicated a different outcome as caffeine and certain major phytoconstituents exhibited antidepressant effects through multiple molecular mechanisms.
Dr. Tenore GC, the lead researcher said, "Coffee can be considered a drink which has different positive effects on human health such as cardioprotective, neuroprotective, hepatoprotective, nephroprotective, etc. However, heavy coffee consumption may be related to some unpleasant symptoms, mainly anxiety, headache, increased blood pressure, nausea, and restlessness".
Contrastively, caffeine in coffee showed a strong inverse association in cases of postpartum depression and comorbid panic disorder.
Other researchers in the search for the efficacy of coffee and the risk of depression through databases from PubMed and PsychINFO insisted that although literature data are conflicting, caffeine found in coffee indicated a significantly reduced effect on symptoms of clinical depression.
Additionally, in a cross-sectional study of 10,177 Korean individuals aged 20-97 years the prevalence of self-reported depression of 14.0%, and of self-reported clinical depression of 3.7%. participated in the fifth Korean National Health and Nutrition Examination Survey. to determine the effect of the consumption of coffee and the risk of depression, after adjusting to other factors, the returned survey from patients can be cataloged into the following
For general depression
1. The relative odd ratio of patients drinking less than one cup/week was 0.84
2. The relative odd ratio of patients drinking one to six cups/week was 0.63
3. The relative odd ratio of patients drinking for one cup/day was 0.69
4. The relative odd ratio of patients drinking for two cups/day was 0.54
5. The relative odd ratio of patients drinking for three or more cups/day was .58
For clinical depression, similar observations also have been recorded
1. The relative odd ratio of patients drinking less than one cup/week was 1.00
2. The relative odd ratio of patients drinking one to six cups/week was 0.51
3. The relative odd ratio of patients drinking for one cup/day was 0.57
4. The relative odd ratio of patients drinking for two cups/day was 0.57
5. The relative odd ratio of patients drinking for three or more cups/day was 0.41
The findings although not linearly, coffee and coffee caffeine intake expressed a protective effect in the ameliorated risk of depression.
Taken together, there is no doubt that coffee and coffee caffeine intake daily and regularly have a profound effect on depression but further cohost large sample-sized studies are necessary to find out other factors that may contribute to either outcome.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, healthblogs, selfgrowth, Best Before it's news, the Karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.
Sources
(1) Coffee and Depression: A Short Review of Literature by Tenore GC1, Daglia M, Orlando V, D'Urso E, Saadat SH, Novellino E, Nabavi SF, Nabavi SM.(PubMed)
(2) [Coffee consumption in depressive disorders: it's not one size fits all].[Article in Italian] by Rusconi AC, Valeriani G, Carluccio GM, Majorana M, Carlone C, Raimondo P, Ripà S, Marino P, Coccanari de Fornari MA, Biondi M.(PubMed)
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