#Healthy Veggie #Broccoli Inhibits Parameters Associated with the Onset of #Hyperlipidemia, According to Studies

Kyle J. Norton

High blood cholesterol is the most common cause of hyperlipidemia. According to statistics provided by the CDC, more than 12% of adults age 20 and older are living with high blood cholesterol with a total cholesterol higher than 240 mg/dL. and more than 18% had high-density lipoprotein (HDL, or “good”) cholesterol levels less than 40 mg/dL.

In other words, hyperlipidemia has a high prevalence ratio that affects over 100 million Americans and the condition is increasing at an alarming rate due to overweight and obesity.

Hyperlipidemia is a medical condition of abnormally high levels of cholesterol and fat in the bloodstream.

The condition is normally known as high blood cholesterol in the general population.

Cholesterol is a waxy substance produced by the liver. In a moderate amount, it helps to improve the gastrointestinal tract in food digestion, builds strong cell membranes, and produces vitamin D and steroid hormones.

Cholesterol can either be produced by the liver or consumed from food sources. There are 2 types of cholesterol
*The high-density lipoprotein also known as "good" cholesterol processes a function to return cholesterol to the liver.

* The low-density lipoprotein is also known as "bad" cholesterol processed a function aforementioned health benefits in a moderate amount.

In a healthy individual, the bad cholesterol is returned to the liver.

People with hyperlipidemia are asymptomatic. Over time, the fat collection in the arteries accompanied by calcium or other substances forms plaque, leading to narrowing arteries and reduced function of the arteries to transport oxygen-rich blood to the parts of the body.

Broccoli is a mustard/cabbage plant, belonging to the family Brassicaceae. The vegetable has large flower heads, usually green in color and the mass of flower heads is surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.

On finding a potential plant that processes anti-anti-hyperlipidemia, researchers examined the serum LDL-cholesterol (LDL-C)-lowering effects of two types of canned beverages containing mixed green vegetables and fruits, with or without broccoli and cabbage (B&C).

The randomized double-blind study design included 77 adult subjects with mild to moderate hypercholesterolemia (Forty-nine out of 77 subjects, whose LDL-C levels were greater than or equal to 140 mg/dl and less than 180 mg/dl) were randomly divided into groups either by a placebo sample made from the same materials but without B&C. The subjects were administered 2 cans of 160 g contents/can) per day for 12 weeks.

According to the results of the experiment,
* Serum LDL-C levels in the test group were significantly reduced at 3, 6, and 9 weeks after administration in comparison to the baseline levels (155.7 mg/dl on average).

* The average LDL-C value at 9 weeks was 142.5 mg/dl and the reduction rate was 8.5% compared to serum LDL-C levels in the control group that was not significantly reduced.

* Significant differences(p < 0.05) between the groups were observed in the LDL-C levels at 6 and 9 weeks and also in the total cholesterol levels at 9 weeks.

Collectively, researchers said, "Intake of the beverage tested containing B&C is useful for lowering serum LDL-C levels in hypercholesterolemic subjects".

Taken altogether, broccoli used combination with cabbage may be considered a functional food for the prevention and treatment of hyperlipidemia, pending to the confirmation of the larger sample size and multicenter human study.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) [LDL-cholesterol-lowering effect of a mixed green vegetable and fruit beverage containing broccoli and cabbage in hypercholesterolemic subjects].[Article in Japanese] by Takai M1, Suido H, Tanaka T, Kotani M, Fujita A, Takeuchi A, Makino T, Sumikawa K, Origasa H, Tsuji K, Nakashima M. (PubMed)

#TualangHoney Inhibits #CervicalCancer Through Its Cytotoxic and Apoptotic Activity, Researchers Suggest

Kyle J. Norton


Scientists may have located a natural whole food for the prevention and treatment of cervical cancer with no side effects, some studies found.
Cervical cancer is a chronic condition caused by cell growth in the tissue of the cervix.


Most cases of cervical cancer start on the cells on the surface of the inner lining tissue of the cervix.
Most patients at this stage of cervical cancer do not experience any symptoms.

As cancer progresses, most patients may experience the symptoms of blood spots or light bleeding between or following periods, longer than usual and heavy menstrual bleeding, increased vaginal discharge, particularly, bleeding after intercourse, and douching.

At this stage, cervical cancer can travel a distance away to cause metastasis to other healthy tissues and organs through fluids and blood circulation.

If you have experienced some of the above symptoms, please check with your doctor to rule out the cervical cancer possibility.


Although certain risk factors such as having many sexual partners, long-term use of birth control pills (oral contraceptives), and early engagement in sexual contact are associated with the onset of the disease, Human papillomavirus (HPV) infection is one of major cause that has been under intensive investigation.

Believe it or not, there are over 100 different HPV types have been identified and classified as high-risk in almost all cervical cancers (>99.7%).

Out of this 100 different HPV, HPV16 is the most prevalent type in both low-grade disease and cervical neoplasia.

Dr. Doorbar J at the National Institute for Medical Research, said, "Most cervical cancers arise within the cervical transformation zone at the squamous/columnar junction, and it has been suggested that this is a site where productive infection may be inefficiently supported"


"Cancers usually arise in individuals who fail to resolve their infection and who retain oncogene expression for years or decades. In most individuals, immune regression eventually leads to clearance of the virus, or to its maintenance in a latent or asymptomatic state in the basal cells".

These results clearly state, that most of the initiation of HPV infection is stopped by the immune system's first line of defense before the virus penetrates through the cervical cell membrane on the surface of the inner lining.

In other words, women who have a weakened immune system are at substantial risk of the disease.

Honey is the miraculous product made by bees using nectar from flowers.

The rich golden liquid is considered one of the healthy sweet foods for replacing the use of white sugar and artificial sweeteners by many people.

In finding a natural ingredient or whole food for the prevention and treatment of cervical cancer, researchers examined the Tualang honey (Agromas) anti-cancer effect.

Tualang honey (Agromas) (TH) were applied with increasing doses of TH (1-10%) for up to 72 h to the human breast (MCF-7 and MDA-MB-231) and cervical (HeLa) cancer cell lines; as well as in the normal breast epithelial cell line, MCF-10A.

At concentrations (EC(50)) of 2.4-2.8%., Tualang honey increased lactate dehydrogenase (LDH) leakage from the cancer cell membranes, an indication of cytotoxicity to all three cancer cells.

Furthermore, the application of TH also reduced the mitochondrial membrane potential (Δψ(m)) in response to energy storage in the cancer cell lines after 24h of treatment.

TH also stimulated the proteins associated with cancer cells apoptosis.

The evidence suggested that TH has significant anticancer activity against human cervical cancer cell lines.

Additionally, in the evaluation of bee bread (BB), a fermented mixture of plant pollen, honey, and bee saliva against the HeLa (cervical carcinoma) cancer cells line, researchers found that the application of BB displays moderate activity in the inhibition of the cancer cell line through cytotoxicity with doses ranging from >400 to 68 µg/mL).

The inhibition of the human cervical cancer cell line was attributed to the main phenolic compounds also found abundantly in the Tualang honey.


The in-depth analysis suggested that BB induces HeLa cell death by stimulating the function of free radicals in the induction of oxidative stress to cause cytotoxicity.

Taken together, honey or Tualang honey may be considered a functional food for the prevention and combined with the primary therapy for the treatment of cervical cancer.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.

Sources
(1) Tualang honey induces apoptosis and disrupts the mitochondrial membrane potential of human breast and cervical cancer cell lines by Fauzi AN1, Norazmi MN, Yaacob NS. (PubMed)
(2) Flavonoid Composition and Antitumor Activity of Bee Bread Collected in Northeast Portugal by Sobral F1, Calhelha RC2, Barros L3,4, Dueñas M5, Tomás A6, Santos-Buelga C7, Vilas-Boas M8, Ferreira IC9. (PubMed)
(3) Molecular biology of human papillomavirus infection and cervical cancer by Doorbar J. (PubMed)

Intake of #Coffee and #Coffee Caffeine Regularly Reduces the Risk of Gallstone and Gallstone Diseases, Researchers Show

Kyle J. Norton

Epidemiological studies, linking coffee consumption to reduced risk of gallstone, but not gallstone disease have been contradictory.
Gallstone is a stone formed within the gallbladder out of bile components as a result of the building up of undissolved cholesterol over a prolonged period of time.

Coffee is a popular and social beverage all over the world, particularly in the West, made from roast beans from the Coffea plant, native to tropical Africa and Madagascar.

In the review of 174 cases of gallstones determined by ultrasonography, 104 cases of postcholecystectomy, and 6889 controls of the normal gallbladder a total of 7637 men received a health examination at four hospitals of the Self-Defense Forces (SDF) with 174 cases of prevalent gallstones, 50 had been aware of having gallstones, researchers found that coffee and coffee caffeine drinkers express a high risk of gallstone incidence in compared to non-drinkers.

In this group of middle-aged Japanese men, the relative odds ratio of gallstone disease is 1.7 for coffee consumption of five cups or more per day vs. no consumption and 2.2 for caffeine intake of 300 mg/day or more vs. less than 100 mg/day.

Obviously, these findings contradicted other studies in support of the risk of gallstones reduced by coffee and caffeine intake, including the study conducted by the Harvard School of Public Health.


In the review literature of database from PubMed and EMBASE of all published studies before June 2015 researchers at The First Affiliated Hospital of Zhengzhou University filed the following results
1. Coffee intake regularly and daily had a significantly reduced risk of gallstone disease, in related females, but not in males. based on prospective studies.

2. For patients drinking one cup of coffee per day, the risk of gallstone disease was 0.95
3. For patients drinking 2, 4, and 6 cups of coffee per day, the estimated RRs of gallstone disease reduced to 0.89 (95% CI, 0.79 to 0.99), 0.81, and .75 respectively.
4, Coffee intake showed a linear association with the ameliorated risk of gallstone diseases.


Interestingly, in a cohort of 80,898 women aged 34-59 years in 1980 who had no history of gallstone disease, during 20 years of follow-up, researchers filed the below results
1. Compared to non-caffeine coffee drinkers women, the multivariate relative risks of gallstone disease with cholecystectomy in comparison to a consistent intake of caffeinated coffee (0, 1, 2-3, and > or =4 cups/day) were 1.0, 0.91, 0.78, and 0.72 respectively.
2. Coffee caffeine intake was inversely associated with the risk of cholecystectomy.
3. Caffeine intake (< or =25, 26-100, 101-200, 201-400, 401-800, and >800 mg/day) is linearly associated with a reduced risk of gallstone disease with the multivariate relative ratio of 1.0, 1.03, 1.01, 0.94, 0.85, and 0.85 4. Decaffeinated coffee was not associated with risk.

There is no doubt that the study addresses a significantly inverse association in reduced risk of gallstone disease among coffee drinkers linearly.


Taken together, the contradictory result may warrant further study before one can make a decision on the effect of coffee and coffee caffeine in concern of risk of gallstone, but not in the attenuated risk of symptomatic gallstone disease.


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months



Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, healthblogs, selfgrowth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.

Sources
(1) Relation of coffee, green tea, and caffeine intake to gallstone disease in middle-aged Japanese men by Ishizuk H1, Eguchi H, Oda T, Ogawa S, Nakagawa K, Honjo S, Kono S.(PubMed)
(2) Systematic review with meta-analysis: coffee consumption and the risk of gallstone disease by Zhang YP1, Li WQ1, Sun YL1, Zhu RT1, Wang WJ1.(PubMed)
(3) A prospective study of coffee consumption and the risk of symptomatic gallstone disease in men by Leitzmann MF1, Willett WC, Rimm EB, Stampfer MJ, Spiegelman D, Colditz GA, Giovannucci E.(PubMed)

#Garlic #Allicin Induces #Cancer Cell Death Through Its Effects on Formation of Apoptotic Bodies, Nuclear Condensation, and a Typical DNA Ladder in Cancer Cells, According to Studies

Kyle J. Norton

Garlic (Allium sativum) may have a potential effect in the prevention and treatment of cancers by gobbling up cancer cells before they can proliferate to the invasive tumor, some studies suggested.
Cancers are a class of chronic diseases characterized by uncontrollable cells grown in tissue in the body.

At the later stage, the cancerous cells can infect other healthy cells and tissue far away from the original site by traveling through blood and lymph.

The diseases are the second cause of death in the US.

According to statistics, between 2011-2015, the National Cancer Institute, 440 per 100,000 adults are diagnosed with cancers, inducing 163.5 per 100,000 death

Depending on the type of cancer, patients may experience certain general and specific symptoms.


DNA alternation caused by an inherited gene mutation in the induction of abnormal cell proliferation is the major cause of cancers.

The National Cancer Institute suggested that age, excessive alcohol consumption, unhealthy diet and lifestyle, smoking, radiation, viruses, carcinogens, obesity,... and chronic inflammation, are also considered some major risk factors that can cause cancers. (As these factors are accumulated through many studies which all point to a similar association between a potential risk factor and an increased risk of cancer).


Garlic (Allium sativum) is a species in the onion genus, belonging to the family Amaryllidaceae, native to central Asia.

The pungent herb has been used popularly in traditional and Chinese medicine for treating common cold and flu, blood pressure cholesterol levels,..... and as a natural antibiotic.

Garlic appears to be generally safe although some people may suffer mild allergic reactions.

A recent study led by author Dr. Oommen S indicated that allicin, the main ingredient found in garlic induces the formation of apoptotic bodies, nuclear condensation, and a typical DNA ladder in cancer cells, causing cell death.

Researchers in the study of the ingredient allicin also showed that the phytochemical is capable of inducing an increase in the rate of apoptosis by obstructing the expression of the cell cycle division and pro-inflammation.

On cancer HL60 and U937 cell lines, allicin inhibits cell growth and induces apoptosis through the mitochondrial pathway by involving the activation of the mitochondrial apoptotic pathway through promoted GSH depletion and changes in the intracellular redox status.

In the research of the function of 20 compounds from garlic, researchers at the Kerala Agricultural University, Kerala, suggested that garlic Phytocompounds Possess Anticancer Activity by Specifically Targeting Breast Cancer Biomarkers.

Other compounds found in garlic such as organosulfur, its extract, and phyto-compounds also suppressed cancer cell proliferation and induced cell cycle arrest.

Therefore, people who are at higher risk of the disease may consider adding a portion of garlic whole food into their diet for preventive measures.

However, further data collection on large example size and multi-center studies performed with human consumption of whole food during the course of the disease will be necessary to complete the picture of garlic anti-cancer possibilities.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Allicin (from garlic) induces caspase-mediated apoptosis in cancer cells by Oommen S1, Anto RJ, Srinivas G, Karunagaran D.(PubMed)
(2) Caspase-independent cell death by allicin in human epithelial carcinoma cells: involvement of PKA by Park SY1, Cho SJ, Kwon HC, Lee KR, Rhee DK, Pyo S.(PubMed)
(3) Allicin inhibits cell growth and induces apoptosis through the mitochondrial pathway in HL60 and U937 cells by Miron T1, Wilchek M, Sharp A, Nakagawa Y, Naoi M, Nozawa Y, Akao Y.(PubMed)
(4) Garlic Phytocompounds Possess Anticancer Activity by Specifically Targeting Breast Cancer Biomarkers - an in Silico Study by Roy N1, Davis S, Narayanankutty A, Nazeem P, Babu T, Abida P, Valsala P, Raghavamenon AC.(PubMed)
(5) Garlic-derived organosulfur compound exerts antitumor efficacy via activation of MAPK pathway and modulation of cytokines in SGC-7901 tumor-bearing mice by Jiang X1, Zhu X1, Huang W1, Xu H1, Zhao Z2, Li S1, Li S3, Cai J3, Cao J3.(PubMed)
(6) Garlic extract in bladder cancer prevention: Evidence from T24 bladder cancer cell xenograft model, tissue microarray, and gene network analysis by Kim WT1, Seo SP2, Byun YJ1, Kang HW1, Kim YJ1, Lee SC1, Jeong P1, Seo Y3, Choe SY3, Kim DJ4, Kim SK5, Moon SK6, Choi YH7, Lee GT8, Kim IY8, Yun SJ1, Kim WJ1.(PubMed)
(7) EGFR gene regulation in colorectal cancer cells by garlic phytocompounds with special emphasis on S-Allyl-L-Cysteine Sulfoxide by Roy N1, Nazeem PA2, Babu TD3, Abida PS2, Narayanankutty A3, Valsalan R2, Valsala PA2, Raghavamenon AC3.(PubMed)

#CruciferousVegetables Decrease the Risk of Kidney Cancer, Reserachers Suggest

Kyle J. Norton

The kidneys are two bean-shaped organs located just below the rib cage, one on each side of your spine.
The kidneys formed a second detoxed organ in the body after the liver not only plays an essential role in regulating electrolytes, and blood pressure, maintains acid-base balance, and produces hormone calcitriol, renin, and erythropoietin,... but also filters blood that passes into the tubules.

In the urinary system, kidneys reabsorb some necessary substances back into the blood, while waste, such as urea and ammonium is deposited into the pelvis and then into the ureter to the bladder for secretion.

Kidney Cancer is a medical condition characterized by irregular cell growth in the tissue of the kidneys.
At the later stage, the cancerous cells may travel a distance way to infect other organs' tissues.
For example, if kidney cancer spreads to the lung is called kidney cancer with lung metastases.

At the very early stage of the kidney, cancerous tumors are localized on the surface of the kidneys.


The most common type of kidney cancer is renal cell cancer.

The causes of kidney cancer are unknown. Some researchers suggested that genetic mutation, cigarette smoking, obesity, family history,..... and exposure to chemicals, such as asbestos and benzene are all associated with increased risk of kidney cancer.

Kidney cancer affects only 2% of the general population. Approximately 14 percent of the US population suffers some form of chronic kidney disease (CKD), including 661,000 cases of kidney failure.

Cruciferous vegetables are a group of vegetables, belongings to the family Brassicaceae (also called Cruciferae) with many genera, and species, and cultivated all over the world in suitable climates for commercial profits, including cauliflower, cabbage, kale, garden cress, bok choy, broccoli, Brussels sprouts, and green leafy vegetables.

In finding a potential remedy for reducing the risk of chronic diseases, researchers examined the effects of cruciferous vegetable consumption in the risk of renal cell carcinoma.

The meta-analysis included 3 cohort and 7 case-control studies retrieved via both computerized searches and review of references.

According to the summary of the calculation of the relative risks (RRs) with 95% confidence interval (CI) for the highest vs. the lowest consumption of cruciferous vegetables,

in cruciferous vegetable consumption group (RR = 0.73; 95% CI, 0.63-0.83) and a subgroup of case-control studies (RR = 0.69; 95% CI, 0.60-0.78), compared to statistically insignificant in cohort studies (RR = 0.96; 95% CI, 0.71-1.21).

No heterogeneity and publication bias was detected across studies.


In other words, the meta-analysis supported cruciferous vegetable consumption for decreasing the risk of renal cell carcinoma.

However, because of the limited number of studies, researchers said, "further well-designed prospective studies and researches need to be conducted to better clarify the protective effect of cruciferous vegetables on renal cell carcinoma and potential mechanism".


Taken together, cruciferous vegetables may be considered functional remedies for the prevention of kidney cancer, pending the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Cruciferous vegetable consumption and risk of renal cell carcinoma: a meta-analysis by Liu B1, Mao Q, Wang X, Zhou F, Luo J, Wang C, Lin Y, Zheng X, Xie L. (PubMed)

#GreenTea EGCG Enhances #Antioxidant Status-Induced Neuroprotective Effect Against the Onset of #Dementia, Reserachers Reveal

Kyle J. Norton

Dementia is the loss of mental ability that is severe enough to interfere with people's every life and Alzheimer's disease is the most common type of dementia in aging people. About 5-8% of all people over the age of 65 have some form of dementia, and this number doubles every five years above that age.
Green tea may be used as a functional food for the prevention of early-onset and treatment of dementia due to aging progression, a renowned institute study suggested

Green tea, a precious drink processes a number of health benefits known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine, or food, long-term injection of large amounts may obstruct the balance of yin-yang, inducing "yin excessive syndrome" or "yang vacuity syndrome", according to traditional Chinese medicine's Yin-Yang theory. Adding a slice of ginger will do the neutralization trick.

In the 5.7-year prospective cohort study, using a questionnaire, information on daily green tea consumption, and other lifestyle factors collected from elderly Japanese individuals aged 65 years or more, green tea consumption is associated with a reduced risk of dementia with an incidence of the occurrent rate of 8.7%.

Furthermore, in the intracerebroventricular (ICV) infusion of streptozotocin (STZ) animal model explicted chronic brain dysfunction involved long-term and progressive deficits in learning, memory, and cognitive behavior, along with a permanent and ongoing cerebral energy deficit, mice treated with green tea EGCG at a dose of 10mg/kg/day for 4 weeks, showed a significant improvement in reduced oxidative stress parameter against the production of inflammatory and free radical expression.

These inhibitions can be seen in the diminished AChE activity, glutathione peroxidase activity as well as NO metabolites, and reactive oxygen species contents

More importantly, the enhanced antioxidant status-induced neuroprotective effect is a result of EGCG injection in ameliorated inflammatory and free radical causes of cell death in the brain of treated mice.


Dr. Tomata Y, the lead author of the study said, "The lower risk of incident dementia was consistent even after selecting participants who did not have subjective memory complaints at the baseline."


More explicitly, in the finding of natural food for reverse or delay risk factors of dementia and AD, vascular, metabolic, and lifestyle-related factors involved in the development of dementia and late-life cognitive disorders, green tea with a high amount of caffeine stimulates the psychoactive effects in attenuated cognitive impairment/decline and dementia through heightened alertness and arousal and improvement of cognitive performance.

Promisingly, such results have been proposed by several cross-sectional and longitudinal population-based studies, particularly in patients with mild cognitive impairment and progression to dementia.


There is no doubt that green tea may be considered as a function of foods for reduced risk of early-onset and delayed progression of dementia, but longer follow-up periods are necessary before the use of green tea can open new ways for diet-related prevention and treatment of dementia.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Sources
(1) Green Tea Consumption and the Risk of Incident Dementia in Elderly Japanese: The Ohsaki Cohort 2006 Study by Tomata Y1, Sugiyama K2, Kaiho Y2, Honkura K2, Watanabe T2, Zhang S2, Sugawara Y2, Tsuji I2(PubMed)
(2) Green tea (-)epigallocatechin-3-gallate reverses oxidative stress and reduces acetylcholinesterase activity in a streptozotocin-induced model of dementia by Biasibetti R1, Tramontina AC, Costa AP, Dutra MF, Quincozes-Santos A, Nardin P, Bernardi CL, Wartchow KM, Lunardi PS, Gonçalves CA.(PubMed)
(3) Coffee, tea, and caffeine consumption and prevention of late-life cognitive decline and dementia: a systematic review by Panza F1, Solfrizzi V, Barulli MR, Bonfiglio C, Guerra V, Osella A, Seripa D, Sabbà C, Pilotto A, Logroscino G.(PubMed)

#ManukaHoney Protectes the Mucosa from Lesions and Preserved Gastric Mucosal Glycoprotein Against the Risk of Ulccers through Its Antioxidant Activity, Researchers Say

Kyle J. Norton

Honey may be the next pharmaceutical target to identify the single ingredient medicine for the treatment of diseases associated with oxidative stress, some scientists suggested.

Oxidative stress is a result of an imbalance in the ratio of free radicals and antioxidants in the body.

Free radicals are highly reactive molecules with an unpaired electron on the outer ring of the atom.
Due to its nature to become stable, free radicals readily to donate or steal an electron from other molecules, leading to the chain of domino's effect that can not be stopped until either the electrons are paired or inhibited by antioxidants.

This chain of reaction is the cause of oxidative stress, a condition associated with either overexpression of free radicals or depletion of antioxidant enzymes produced by the host organs.

Overexpression of free radicals is known to cause damage in contributing to the etiology many chronic health problems such as cardiovascular and inflammatory disease, cataract, and cancer.
Antioxidants, on the other hand, are stable molecules with a unique function in the inhibition of oxidation.

Dr. V. Lobo, the lead author in the study "Free radicals, antioxidants, and functional foods: Impact on human health" wrote, " A balance between free radicals and antioxidants is necessary for proper physiological function. If free radicals overwhelm the body's ability to regulate them, a condition known as oxidative stress ensues", and

"Free radicals thus adversely alter lipids, proteins, and DNA and trigger a number of human diseases. Hence application of an external source of antioxidants can assist in coping with this oxidative stress. Synthetic antioxidants such as butylated hydroxytoluene and butylated hydroxyanisole have recently been reported to be dangerous for human health".

These results suggested that regardless of the causes of the overexpression of free radicals, intake of dietary sources of antioxidants from a supplement, herbs, fruits, and vegetables can be beneficial in restoring the healthy ratio of free radicals and antioxidants and preventing the onset of oxidative stress.

Honey is the miraculous product made by bees using nectar from flowers.

The rich golden liquid It is considered one of healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.

In order to understand the honey antioxidant activity which has been under intensified study by the science community, a joint study led by the researchers conducted was conducted in an animal model.

Ethanol-induced gastric ulcers in rats were randomly assigned to control, ethanol (ulcer), omeprazole, and manuka honey.

Honey-treated rats displayed a clinically significant decrease in the ulcer index by completely protecting the mucosa from lesions and preserved gastric mucosal glycoprotein.

Application of manuka honey also decreased gastric mucosal MDA, the marker of oxidative stress and plasma TNF-α, IL-1β, and IL-6 concentrations, the set of proinflammatory cytokines produced by the ethanol injection.


These results were attributed to the manuka honey in stimulating the production of antioxidant enzymes which were suppressed by the injection of ethanol in the tested rats.

The finding suggested that manuka honey exerted a strong antioxidant activity by balancing the ratio of free radicals and antioxidant enzymes in the treatment group.


In other words, manuka honey inhibited the oxidative stress caused by overexpression of free radicals in the initiation of the onset of the ulcer.

Further differentiation to reaffirm the effects of manuka honey in the inhibition of gastric ulcers in the rat model, researchers examined three different concentrations of honey applied to the tested rats.

During the experiment, researchers found that all 3 different concentrations display a strong effect in It reducing the mucosal myeloperoxidase activity, lipid peroxidation (MDA), and the inflammatory cytokines (TNF-α, IL-1β, and IL-6) compared to the untreated control group.

In other words, manuka honey protects the rat stomach by inhibiting the overexpression of free radicals and pro-inflammatory cytokines inducing oxidative stress.

Application manuka honey also showed a significant increase in enzymatic (GPx and SOD) and non-enzymatic (GSH) antioxidants which were reduced due to ulcer and levels of the anti-inflammatory cytokine IL-10.


The Flow cytometry assay also indicated that treatment of rats with manuka honey has normalized cell cycle distribution and significantly lowered apoptosis in gastric mucosa.

The information collected strongly supports the use of manuka honey for the treatment of chronic ulcers and the preservation of mucosal glycoproteins.

Dr. Almasaudi SB wrote in the final report, "Its (manuka honey) effects are due to its antioxidant and anti-inflammatory properties that resulted in a significant reduction of the gastric mucosal MDA, TNF-α, IL-1β, and IL-6 and caused an elevation in IL-10 levels.


Taken all together, there is no doubt that manuka honey high in antioxidants can be considered a functional food for the prevention and combined with the primary medicine for the treatment of diseases associated with oxidative stress.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) Antioxidant, Anti-inflammatory, and Antiulcer Potential of Manuka Honey against Gastric Ulcer in Rats by Almasaudi SB1, El-Shitany NA2, Abbas AT3, Abdel-dayem UA4, Ali SS5, Al Jaouni SK6, Harakeh S. (PubMed)
(2) Manuka Honey Exerts Antioxidant and Anti-Inflammatory Activities That Promote Healing of Acetic Acid-Induced Gastric Ulcer in Rats by Almasaudi SB1, Abbas AT2, Al-Hindi RR1, El-Shitany NA3, Abdel-Dayem UA4, Ali SS5, Saleh RM6, Al Jaouni SK7, Kamal MA8, Harakeh SM. (PubMed)
(3) Protective effects of Manuka honey on LPS-treated RAW 264.7 macrophages. Part 2: Control of oxidative stress induced damage, increase of antioxidant enzyme activities and attenuation of inflammation by Gasparrini M1, Afrin S1, Forbes-Hernández TY1, Cianciosi D1, Reboredo-Rodriguez P2, Amici A1, Battino M1, Giampieri F3. (PubMed)
(4) The inflammation theory of diseas. The growing realization that chronic inflammation is crucial in many diseases opens new avenues for treatment by Philip Hunter. (PubMed)