#GreenTea, Bioactive Epigallocatechin-3-O-(3-O-methyl) Gallate (EGCG3"Me)Enhances the Immune Function Against the Allergic Initiation, Researchers Say

Kyle J. Norton

Green tea may have a particular and special effect in ameliorating autoimmunity in the precipitation of allergic diseases, some scientists opinionated.

Green tea, a precious drink processes a number of health benefits known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine or food, long-term injection of large amounts may obstruct the balance of yin-yang, inducing "yin excessive syndrome" or "yang vacuity syndrome" including weakened immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory.

Allergic diseases are a class of conditions characterized by an overreaction of the immune system to substances that cause little or no harm to the body.

Investigation of the effect of green tea bioactive compounds in reduced abnormal immune allergic expression was found to associate with certain mechanisms.

According to the Kyushu University, Epigallocatechin-3-O-(3-O-methyl) gallate (EGCG3"Me) isolated from cv. "Benifuuki" green tea expressed strong and positive activities in inhibiting the mast cell production in precipitated allergic inflammatory responses and suppressed the high-affinity IgE receptor (FcεRI) function in the expression of immunoglobulin E (IgE), an antibody isotype involved in allergy disorder through 67 kDa laminin receptor in the mediation of the suppressive effect by epigallocatechin-3-O-gallate.

Further analysis also found that the bioactive compound binds to 67 kDa laminin receptor to attenuate allergic expression induced by mast cells by suppressing the myosin light chain phosphorylation in the regulated immune response to eosinophil (a type of disease-fighting white blood cell) migration in the tissue, a characteristic feature of allergic diseases and ERK1/2 phosphorylation signaling by modulation of inflammatory cytokines expression.


In a double-blind clinical study of the green tea effect on subjects exposed to Japanese cedar pollinosis, administration of Benifuuki green tea containing O-methylated catechins showed significantly relieving allergic symptoms induced by pollen such as nose blowing, and eye itching compared with the placebo group without affecting the In normal immune responses.

More interestingly, in mouse bone marrow-derived mast cells activated by antigens, bioactive compound epigallocatechin-3-O-(3-O-methyl) gallate (EGCG3″Me) in combination with ginger extract also demonstrated a strongly anti-delay-type allergic effect by suppressing cytokines secretion of tumor necrosis factor (TNF-α), a cell-signaling protein (cytokine) in response to systemic inflammation in the acute phase infection. and macrophage Inflammatory Proteins(MIP-1α), a chemokine-involved host response to invading bacteria and viruses.

Compared to the dose of 5.1 times higher in EGCG, injection of 8.5 mg of EGCG3″Me exhibited much stronger anti-allergic activity than 43.5 mg of EGCG, observed by the area under the curve AUC (area under the drug concentration-time curve; min μg/ml) of 6.72 ± 2.87 in EGCG and 8.48 ± 2.54 in EGCG3″Me.

Taken together, green tea with abundantly bioactive Epigallocatechin-3-O-(3-O-methyl) gallate (EGCG3"Me) may be considered a functional food for protection against autoimmune response stimulated by unharmful allergens.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, healthblogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.

Sources
(*) Anti-Allergic Action of O-methylated EGCG in Green Tea Cultivar Benifuuki by MARI MAEDA-YAMAMOTO1 * AND HIROFUMI TACHIBANA2(Journal of Food and Drug Analysis, Vol. 20, Suppl. 1, 2012, Pages 313-317)
(1) Human clinical studies of tea polyphenols in allergy or life style-related diseases by Maeda-Yamamoto M1.(PubMed)(2) In vitro and in vivo anti-allergic effects of ‘benifuuki’ green tea containing O-methylated catechin and ginger extract enhancement by Mari Maeda-Yamamoto,1 Kaori Ema,1 and Ikuo Shibuichi2(PubMed)

#Garlic Phytocompounds Poccess Anticancer Activity, According to Studies

Kyle J. Norton

Garlic (Allium sativum) is a species in the onion genus, belonging to the family Amaryllidaceae, native to central Asia. It has been used popularly in traditional and Chinese medicine in treating the common cold and flu, blood pressure cholesterol levels, natural antibiotics, etc. but Garlic appears to be generally safe although allergic reactions may occur.

Cancer is a class of diseases in which a group of cells growing and multiplying disordered and uncontrollable way in our body, have become progressively worse and damaged other healthy tissues. Sometimes cancer cells spread to other organs in the body via lymph or blood and results may be in death.

A recent study led by author Dr. Oommen S indicated that allicin, the main ingredient found in garlic induced the formation of apoptotic bodies, nuclear condensation, and a typical DNA ladder in cancer cells, causing cell death.

Researchers in the study of ingredient allicin also showed that the phytochemical was capable of inducing an increase in the rate of apoptosis by affecting the expression of the cell cycle division and negation of pro-inflammation.


In cancer HL60 and U937 cell lines, allicin inhibits cell growth and induces apoptosis through the mitochondrial pathway by involving the activation of the mitochondrial apoptotic pathway by GSH depletion and by changes in the intracellular redox status.

In the research of the function of 20 compounds from garlic, researchers at the Kerala Agricultural University, Kerala, suggested that garlic Phytocompounds Possess Anticancer Activity by Specifically Targeting Breast Cancer Biomarkers.


Other compounds found in garlic such as organosulfur, its extract, and phytocompounds also suppress cancer cell proliferation and induced cell cycle arrest.

Therefore, people with or without cancers may consider adding a portion of garlic whole food into their diet for the prevention, management, and treatment of the disease.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.


Sources
(1) Allicin (from garlic) induces caspase-mediated apoptosis in cancer cells by Oommen S1, Anto RJ, Srinivas G, Karunagaran D.(PubMed)
(2) Caspase-independent cell death by allicin in human epithelial carcinoma cells: involvement of PKA by Park SY1, Cho SJ, Kwon HC, Lee KR, Rhee DK, Pyo S.(PubMed)
(3) Allicin inhibits cell growth and induces apoptosis through the mitochondrial pathway in HL60 and U937 cells by Miron T1, Wilchek M, Sharp A, Nakagawa Y, Naoi M, Nozawa Y, Akao Y.(PubMed)
(4) Garlic Phytocompounds Possess Anticancer Activity by Specifically Targeting Breast Cancer Biomarkers - an in Silico Study by Roy N1, Davis S, Narayanankutty A, Nazeem P, Babu T, Abida P, Valsala P, Raghavamenon AC. (PubMed)
(5) Garlic-derived organosulfur compound exerts antitumor efficacy via activation of MAPK pathway and modulation of cytokines in SGC-7901 tumor-bearing mice by Jiang X1, Zhu X1, Huang W1, Xu H1, Zhao Z2, Li S1, Li S3, Cai J3, Cao J3. (PubMed)
(6) Garlic extract in bladder cancer prevention: Evidence from T24 bladder cancer cell xenograft model, tissue microarray, and gene network analysis by Kim WT1, Seo SP2, Byun YJ1, Kang HW1, Kim YJ1, Lee SC1, Jeong P1, Seo Y3, Choe SY3, Kim DJ4, Kim SK5, Moon SK6, Choi YH7, Lee GT8, Kim IY8, Yun SJ1, Kim WJ1.(PubMed)
(7) EGFR gene regulation in colorectal cancer cells by garlic phytocompounds with special emphasis on S-Allyl-L-Cysteine Sulfoxide by Roy N1, Nazeem PA2, Babu TD3, Abida PS2, Narayanankutty A3, Valsalan R2, Valsala PA2, Raghavamenon AC3.(PubMed)

#Andrographis Inhibits Parameters Associated with the Onset of #NeurodegenerativeDiseases including #Alzheimer's disease AD, Researchers Say

Kyle J. Norton

The good news for aging people with neurodegenerative diseases, Andrographis paniculata possesses potent anti-inflammatory activity in the expression of neurodegeneration a study by a renowned institute suggested.
Andrographis paniculata, also known as Andrographis is a herbaceous plant, genus Andrographis, belonging to the family Acanthaceae, native to India and Sri Lanka, used in traditional Siddha and Ayurvedic in treating the common cold, flu, upper respiratory infections, infectious diseases, diarrhea, dysentery, cholera, pneumonia,......

Andrographolide, a major phytochemical isolated from Andrographis paniculata, exerted significant anti-neuro deficits in reduced infarct volume with a maximum reduction of approximately 50% at a dose of 0.1 mg·kg(-1).


According to the National University of Singapore, the efficacy of the chemical compound in neuroprotective effects is the result of the suppression of NF-κB, a protein in regulated cell survival and function of microglia in the activated response to brain injuries and immunological stimuli together with the reduction in the production of inflammatory cytokines.

Dr. Chan SJ, the lead research said, "Andrographolide, given i.p. 1 h after pMCAO, reduced infarct volume with a maximum reduction of approximately 50% obtained at 0.1 mg·kg(-1)".

Octodon degus (degu) is the only wild-type South American rodent that develops Alzheimer's-like pathology with age. the progression of AD in these animals is associated with aging on the loss of cognitive function, causing a decrease in the synaptic functions and an increase in the main hallmarks of Alzheimer's disease (AD).

Natural product (Andrographolide, ANDRO), administered to aged degus (56-month old) for 3 months, in compared 2 control groups (young degus: 12-month old and aged degus: 56-month old), showed a recovery of spatial memory and learning performance, synaptic basal transmission; and enhancing the neuroprotective effect, through reduced phosphorylated tau protein and reduced amyloid beta aggregate maturation in involving neurodegeneration in Alzheimer's disease (AD) in Andrographolide, ANDRO treated subjects.

Taken together, Andrographis could be used as a functional food in potential therapy for AD-associated neural damage due to aging processes and neuropathological hallmarks of aging-related diseases such as AD.



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Sources
(1) Neuroprotective effects of andrographolide in a rat model of permanent cerebral ischemia by Chan SJ1, Wong WS, Wong PT, Bian JS(PubMed)
(2) Andrographolide recovers cognitive impairment in a natural model of Alzheimer's disease (Octodon degus) by Rivera DS1, Lindsay C2, Codocedo JF2, Morel I3, Pinto C2, Cisternas P4, Bozinovic F5, Inestrosa NC6.(PubMed)

#Herbal Turmeric's #Curcumin Decreases Levels of #Hyperlipidemia by Reducing Body Weight, Liver Weight, and Adipose Weight, Researchers say

Kyle J. Norton

Hyperlipidemia is a chronic condition of abnormally high levels of any or all lipoproteins in the bloodstream, including cholesterol and triglycerides.
The condition is normally known as high blood cholesterol in the general population.

People with hyperlipidemia are asymptomatic. Over time, the fat collection in the arteries accompanied by calcium or other substances form plague, leading to narrowing arteries and reduced function of the arteries to transport oxygen-rich blood to the parts of the body.

According to the statistics provided by the CDC, in 2015–2016, more than 12% of adults age 20 and older had total cholesterol higher than 240 mg/dL, and more than 18% had high-density lipoprotein (HDL, or “good”) cholesterol levels less than 40 mg/dL.

Believe it or not, about half of the U.S. adults (55%, or 43 million) are currently taking medicine associated with lower blood cholesterol.

There are many risk factors that cause the onset of hyperlipidemia, such as people with diabetes, being overweight gain, physical activity, and smoking.

Some researchers suggested the promotion of a high-fat diet over the past decades may be one of the silent causes of hyperlipidemia in the Western world.

Dr. Charles Desmarchelier in the examined the risk of high blood cholesterol in a high-fat diet model said, "Mice on Western diet showed increased plasma cholesterol levels, associated with the higher dietary cholesterol supply, yet, significantly reduced cholesterol levels were found in intestine and liver".

And, "(The) intestine and liver react to a high dietary fat intake by activation of de novo cholesterol synthesis and other cholesterol-saving mechanisms, as well as with major changes in phospholipid metabolism, to accommodate to the fat load'.

Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.

The herb has been used in traditional medicine as antioxidant, hypoglycemic, antiseptic, wound healing agent, and to treat flatulence, bloating, appetite loss, ulcers, eczema, inflammations, etc.
With an aim to find a natural ingredient for the treatment of hyperlipidemia, researchers investigated the effects of curcumin on hyperlipidemia and hepatic steatosis in high-fructose-fed Wistar rats.

The study included 40 male Wistar rats divided into four groups with 10 rats in each. Two groups were fed with a standard rodent diet and the other two with a 60% high-fructose diet for 10 weeks. Curcumin (200 mg/kg body weight) was administered along with the diets simultaneously to each of the aforementioned diet groups.

After 10 weeks of the experiment, researchers found that curcumin decreased the levels of hyperlipidemia observed by reducing body weight, liver weight, and adipose weight.

The plasma levels of triglyceride inhibited the proteins associated with fat cell fat metabolism, and lipid ratios, and increased HDL-C (28.4 ± 4.5 mg/dL) in fructose-fed rats were also lower by the injection of curcumin.

Furthermore, curcumin also suppressed the lipogenic enzymes involved in regulating lipogenesis in fat cells.

Taken altogether, turmeric processed with a high amount of curcumin may be used for the prevention and treatment of hyperlipidemia, pending the confirmation of the larger sample size and multicenter human study.


Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Curcumin inhibits hyperlipidemia and hepatic fat accumulation in high-fructose-fed male Wistar rats by Maithilikarpagaselvi N1, Sridhar MG1, Swaminathan RP2, Sripradha R1, Badhe B. (PubMed)
(2) Highly bioavailable micellar curcuminoids accumulate in blood, are safe and do not reduce blood lipids and inflammation markers in moderately hyperlipidemic individuals by Kocher A1, Bohnert L1, Schiborr C1, Frank J, (PubMed)
(3) C57Bl/6 N mice on a western diet display reduced intestinal and hepatic cholesterol levels despite a plasma hypercholesterolemia by Charles Desmarchelier,1 Christoph Dahlhoff,1,2 Sylvia Keller,3 Manuela Sailer,1Gerhard Jahreis,3 and Hannelore Daniel. (PMC)

#Aloe Vera Reduces Aging Wrinkle by Stimulating the Production of Collagen and Hyaluronic Acid, Researchers Suggest

Kyle J. Norton

Aloe Vera or Aloe Vera supplements may be used to delay skin aging degeneration in the induced expression of wrinkles.
Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan. It is very popular for commercial cultivation due to its health benefits, used in herbal medicine in treating many kinds of diseases, including wounds, burn healing, minor skin infections, sebaceous cysts, diabetes, elevated cholesterol, etc.

The wrinkle is a skin degenerative condition caused by the loss of the dermis and the subcutaneous fat layer underneath the skin, leading to a slight line or fold on the skin, particularly in the face.


According to the Food Ingredients & Technology Institute, daily oral intake of plant sterols of Aloe vera gel (Aloe sterol) significantly increases the skin barrier function, moisture, and elasticity in photoprotected skin that may reduce the risk of skin wrinkles.

In a 12-week, randomized, double-blind, placebo-controlled study, in 48 apparently healthy men (age range: 30-59 years; average: 45 years), intake of oral Aloe sterol supplementation after 12 weeks showed a significant improvement of the skin elasticity index in comparison in the baseline value.

Dr. Tanaka M, the lead author said, "Aloe sterol ingestion increased skin elasticity in the photodamaged skin of men aged <46 years, and "No Aloe sterol intake-dependent harmful phenomenon was observed during the intake period".

Furthermore, in vitro, Aloe sterols increased the production of collagen and hyaluronic acid, a natural substance in skin response to connective, epithelial, and neural tissues. approximately two-fold and 1.5-fold, and promoted gene expression levels in human dermal fibroblasts.


In fact, daily oral Aloe sterol-containing Aloe vera gel powder (AVGP) significantly reduced facial wrinkles in women aged ≥40 years as well as stimulated collagen and hyaluronic acid production by human dermal fibroblasts.

In support of the above evaluation, intake of Aloe Vera gel enhanced healthy skin through promoting elasticity (R2), net elasticity (R5), and biological elasticity (R7) scores and skin fatigue area F3, the Food Ingredients and Technology Institute 12 weeks study suggested.


Taken together, there is no doubt that oral administration of Aloe Vera or Aloe Vera supplements may improve skin conditions caused by skin aging degeneration, but the quality of amount intake should only be prescribed by related field specialists.



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Sources
(1) Effects of plant sterols derived from Aloe vera gel on human dermal fibroblasts in vitro and on skin condition in Japanese women by Tanaka M1, Misawa E1, Yamauchi K1, Abe F1, Ishizaki C2.(PubMed)
(2) Effects of Aloe Sterol Supplementation on Skin Elasticity, Hydration, and Collagen Score: A 12-Week Double-Blind, Randomized, Controlled Trial by Tanaka M1, Yamamoto Y, Misawa E, Nabeshima K, Saito M, Yamauchi K, Abe F, Furukawa F.(PubMed)
(3) Aloe sterol supplementation improves skin elasticity in Japanese men with sunlight-exposed skin: a 12-week double-blind, randomized controlled trial by Tanaka M1, Yamamoto Y2, Misawa E1, Nabeshima K1, Saito M1, Yamauchi K1, Abe F1, Furukawa F2. (PubMed)

#BlackBean Inhibits #ProstateCancer by Decreasing Cancer Cell Energy Molecules and Formation of Cell Structure, Researchers Find

Kyle J. Norton

Intake of black beans regularly may associate with ameliorated risk and treatment of prostate cancer, an Asian study reported. Particularly, people who follow the Southern pattern of diet showed a reduction in the risk of prostate cancer with approached statistical significance.

Black bean, a small roughly ovoid legume with glossy black shells, genus Phaseolus, belongings to the family Fabaceae can be bought in most grocery stores all around the year in dried and canned forms. It is believed that black bean was the first domesticated growth in South America.

According to the National Taiwan University, fermentation products BN999, including black bean processed an anti-prostate cancer effect through the expression of the prostate adenocarcinoma PC-3 cell line.

BN999, the product mixture induced cancer cell death by activating the protein gene involved in pro-cancer cell apoptosis via cell mediatory activities, including a network of membranous anatomical structures and double membrane-bound organelle in energy conversion.

Most importantly, BN999 targets the prostate and other cancer cells without affecting normal human cells and inducing obvious side effects.

Furthermore, water-soluble black bean condensed tannins isolated from black beans showed significant activity in induced cancer cell death by apoptosis without affecting the growth of normal cells, in a dose-dependent manner.

Additionally, the study also addressed that the efficacy of water-soluble in induced prostate cancer cell death may be attributed to a direct effect in decreasing cancer cell energy molecules and formation of cell structure.

Dr. Bawadi HA, the lead author indicated, after 24 h of injection, water-soluble black bean condensed tannins showed strongly reduced coagulation of blood in stimulated cancer cell migration and regulated mechanisms involved in the growth of prostate cancer in the formation of new blood vessels.

The findings suggested that black beans with plenty of phytochemicals may be considered a functional food used alone or in combination with other superfoods for attenuated risk and treatment of prostate cancer.


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, healthblogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.

Sources
(1) Fermentation product of soybean, black bean, and green bean mixture induces apoptosis in a wide variety of cancer cells by Chia JS1, Du JL, Wu MS, Hsu WB, Chiang CP, Sun A, Lu JJ, Wang WB.(PubMed)
(2) Dietary patterns and prostate cancer risk in the National Health and Nutrition Examination Survey Epidemiological Follow-up Study cohort by Tseng M1, Breslow RA, DeVellis RF, Ziegler RG.(PubMed)

#Ginger #Extract Inhibits Symptoms of Nausea and Vomiting Induced by #ChemoDrug or #Pregnancy, Researchers Say

Kyle J. Norton

Scientists may have discovered a pungent kitchen spice that processes a significant effect in reducing nausea and vomiting with no side effects, according to some studies.

Nausea and vomiting are the natural protection of the digestive system reacted to many causes, including food poisoning, gastritis (inflammation of the stomach lining), an ulcer, or bulimia.

Morning sickness or nausea and vomiting are common experiences in pregnancy, affecting 70–80% of all pregnant women.

Nausea and vomiting that often develop by five to six weeks of pregnancy are the results of the rise of the hormone estrogen in the early stage of pregnancy. The syndrome may get even worse in women who have sensitive stomach that tries to adapt to the changes of pregnancy.


Morning sickness in pregnancy may seem obvious in the general population, however in a group of women with severe nausea and vomiting during pregnancy due to hyperemesis gravidarum (HG), an entity distinct from nausea and vomiting during pregnancy (NVP), may lead to significant maternal and fetal morbidity if untreated.

Dr.Noel M. Lee, the lead author at the University of Wisconsin School of Medicine and Public Health in the study " Nausea and Vomiting of Pregnancy" said, "Various metabolic and neuromuscular factors have been implicated in the pathogenesis of NVP and HG; however, their exact cause is unknown. Consequently, treatment of NVP and HG can be difficult as neither the optimal targets for treatment nor the full effects of potential treatments on the developing fetus are known".

Where hyperemesis gravidarum (HG) is a pregnancy complication characterized by severe nausea, vomiting, weight loss, and possibly dehydration.

Other causes of nausea and vomiting are due to prolonged period of exposure to stress and long-term fatigue.

Patients who are having chemotherapy are associated with an increased risk of nausea and vomiting because the injection of chemo drugs can affect parts of the stomach and brain that detect toxic (poisonous) substances.

Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.

The pungent spice has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.

With an aim to clarify the effect of ginger extract in treating chemotherapy-induced nausea and vomiting (CINV), a joint study led by Taipei Medical University-Shuang Ho Hospital was conducted to determine whether ginger could be used to treat CINV, which was interpreted using the PICOS (patient, problem/population, intervention, comparison, outcome, study) framework, with P being patients who underwent chemotherapy.

After searching the studies in English from 2000 to 2017 databases. 2 on a total of 10 studies with complete data. was included in the meta-analysis using Comprehensive Meta-analysis.

Ginger exerted a significant effect in reducing the symptoms of nausea and vomiting with the odds ratio (OR) of 0.71

Further analysis also discovered that ginger could only reduce acute CINV in patients, particularly acute vomiting.

After taking an additional ]assessment of the co and confounders, Dr. Chang WP the lead scientist said, "Ginger displayed significant efficacy with regard to controlling CINV in the experimental groups".

In reaffirming the effect of ginger on the early pregnancy symptoms of nausea and vomiting of pregnancy (NVP), a joint study led by the Iran University of Medical Sciences launched an evaluation to compare the effects of ginger, pyridoxine (vitamin B6), and placebo.

The triple-blind clinical trial on pregnant women suffering mild to moderate NVP between 6 and 16 weeks of pregnancy.

In these women ginger, 500 mg twice daily, vitamin B6 40 mg twice daily, and placebo twice daily were administered for 4 d.

The severity of NVP was evaluated 24 h before entering the study and up to 4 d after using medications and results were compared among the three groups.

The women of the three groups did not have significant differences according to age, gestational age, parity, and severity of each symptom before treatment and educational status.

After assessing the returned questionnaires, researchers indicated
* Ginger and vitamin B6 could reduce the severity of all items of the Rhodes questionnaire significantly.

* Ginger and vitamin B6 were more effective than placebo

* total score of Rhodes did not show a significant difference between ginger and vitamin B6 (p = .128). Ginger was more effective for nausea (intensity and distress).

These results once against illustrate the efficacy of ginger in the treatment of nausea and vomiting in early pregnancy.


Taken together, there is no doubt that ginger may be used as a functional food for the treatment of nausea and vomiting in both early pregnancy and the side effects of chemo treatment.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.


Sources
(1) A Meta-analysis of 10 Randomized Controlled Trials by Chang WP1, Peng YX.(PubMed)
(2) A comparison between the effects of ginger, pyridoxine (vitamin B6) and placebo for the treatment of the first trimester nausea and vomiting of pregnancy (NVP) by Sharifzadeh F1, Kashanian M1, Koohpayehzadeh J2, Rezaian F1, Sheikhansari N3, Eshraghi N. (PubMed)
(3) Nausea and Vomiting of Pregnancy by Noel M. Lee, M.D., Gastroenterology Fellow and Sumona Saha, M.D., Assistant Professor of Medicine. (PMC)