Kyle J. Norton
Cholesterol produced by the liver and from dietary sources is needed for the cell to build strong membranes, produce steroid hormone, bile acids, and vitamin D, and aid digestive functioning.
Most people with high blood cholesterol at the early do not experience any symptoms, however, as the levels of blood cholesterol continue to grow, at some points, patients may experience heart-related symptoms, including chest pain or angina, pain while walking caused by reduced blood flow to the legs.
In serious cases, elevated blood cholesterol can also induce symptoms of stroke and heart attack.
There are 2 types of blood cholesterol
* Low-density lipoprotein (LDL) also is known as “bad cholesterol”. Bad cholesterol is a major cause of plaque build-up in the arteries and a leading cause of coronary heart disease.
*High-density lipoprotein (HDL) is known as “good cholesterol”. HDL removes LDL cholesterol from your arteries back to the liver.
The healthy ratio of blood cholesterol is 4 LDL)/ 1HLD
Besides a high-fat diet, certain risk factors such as a family history of high cholesterol, being overweight or obese, physical inactivity, excessive alcohol intake, smoking and some health conditions including diabetes, kidney disease, and liver disease have been found to increase the risk of high blood cholesterol.
Epidemiological studies also suggested that a high level of blood cholesterol is associated with an increased risk of cardiovascular disease.
The endothelium is a thin membrane that lines the inside of the heart and blood vessels. The endothelium cells process an essential function in controlling vascular relaxation and contraction.
Furthermore, the endothelium cells also control enzymes associated with blood clotting, immune function, and platelet adhesion.
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
In finding a potential compound for the treatment of prostate diseases, researchers examined the effect of chronic cranberry juice consumption on cholesterol profiles and vascular functions in an estrogen-deficient animal model.
The study included ovariectomized rats that were treated daily with commercial cranberry juice at 7 mg/kg for 8 weeks, and a dosage comparable to recent clinical studies.
According to the tested analysis, cranberry juice consumption reduced circulating levels of total cholesterol, triacylglycerols, HDL, nHDL, and nHDL/HDL ratio.
Furthermore, cranberry juice consumption improved endothelium-dependent relaxation in the aorta of ovariectomized rats by restoring p-eNOS level (endothelial nitric oxide synthase.
Overexpression of renin-angiotensin system markers (angiotensin-converting enzyme, angiotensin II, and angiotensin II type 1 receptor) associated with blood pressure was also inhibited by commercial cranberry juice.
Furthermore, commercial cranberry juice also normalizes the elevated NAD(P)H oxidase expression and oxidative stress involved in the increased levels of ROS.
Based on the findings, researchers concluded. " the novel cardiovascular benefits of cranberry juice consumption in improving both vascular functions and cholesterol profiles".
Taken together, cranberry may be considered a remedy for the prevention and treatment of cardiovascular disease, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Chronic cranberry juice consumption restores cholesterol profiles and improves endothelial function in ovariectomized rats by Yung LM1, Tian XY, Wong WT, Leung FP, Yung LH, Chen ZY, Lau CW, Vanhoutte PM, Yao X, Huang Y. (PubMed)
Health Researcher and Article Writer. Expert in Health Benefits of Foods, Herbs, and Phytochemicals. Master in Mathematics & Nutrition and BA in World Literature and Literary criticism. All articles written by Kyle J. Norton are for information & education only.
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Any inquiry of published articles, please e mail kylenorton@hotmail.ca
Thursday, 17 August 2023
#Phytochemical #Sinigrin Stimulates a Protein and Gene Associated with A Reduced Risk of #LiverCancer, Researchers Say
Kyle J. Norton
Sinigrin may be the next-generation natural and bioactive compound processed an antiproliferative activity against the progression of cancer, according to studies.
In cancer, antiproliferation is a process in which the cancer cells are killed or limited to grow through many mechanisms, including the use of chemo drugs.
From the immune perspective, anti-proliferation can be carried out by activating the genes associated with cancer suppression, programming cell death,.... and cell cycle arrest.
A suppressive gene, such as pro-apoptotic p53 induces cancer cell death through cell cycle arrest. In other words, the gene inhibits tumor growth by interrupting the cancer cell cycle division.
The programmed cell death gene, such as BCL-2 induce cell death by either inducing or inhibiting apoptosis. In other words, If cells are no longer needed or damaged, activating an intracellular death program will cause cell death.
In phytochemicals, anti-proliferation can also be carried out by antioxidants in which they stimulate the free radicals overexpression to induce toxicity to tumor cells without causing harm to the nearby healthy cells.
Some cancers can stimulate the production of a new blood vessel for cancer cells to grow and others can make enzymes that break down normal cells and tissues as they grow.
Dr. Albanes D, in the study of cell proliferation as a major risk factor for cancer, said, "Caloric restriction strongly inhibits the development of neoplasia in rodents, and there is evidence of a positive relationship between cancer and body weight in humans".
And, "A recent link between adult stature and cancer incidence similarly implicates a lasting effect for growth and possibly for early nutrition in carcinogenesis. It is postulated that cancer risk is proportional to the number of proliferating cells, which in turn depends on both the number of cells and the rate of cell division within the tissue".
Sinigrin is a phytochemical glucosinolate, belonging to the family of glucosides found abundantly in Brussels sprouts, broccoli, the seeds of black mustard, etc.
Researchers on finding a bioactive compound for the treatment of liver cancer, one of the leading causes of cancer death worldwide. investigated the anti-proliferative activity of sinigrin, the major ingredient present in Brassica nigra.
In a model of carcinogen-induced hepatotoxicity in rats, the selected animals were orally administered with sinigrin on a daily basis for three months before sacrifice.
During the experiment, the injection of sinigrin significantly inhibited the proliferation of liver tumor cells, observed by the reduction of the number of surface tumors in the rat liver.
Sinigrin induced apoptosis of liver cancer cells by exhibiting the expression of a protein associated with tumor suppression in the host rats, namely, the p53.
Furthermore, the application of sinigrin-induced cancer apoptosis by stimulating the production of a protein involved in cell death programming and a gene involved in cellular differentiation.
Interestingly, in the additional analysis of the sinigrin anti-liver cancer activity, researchers showed that the bioactive compound not only inhibits cancer cells from proliferation through cell cycle arrest but also restores liver function without inducing liver toxicity.
The results strongly suggested that sinigrin processed significant anti-liver cancer properties via several genes and pathways.
Dr. Jie M, the lead scientist wrote in the final report, "Sinigrin exerts important anti-proliferative activities in carcinogen-induced hepatocarcinogenesis in rats, and highlights the potential of sinigrin as an anti-cancer agent for liver cancer".
Taken altogether, sinigrin found in Brassica nigra may be considered a functional supplement for the prevention and treatment of liver cancer, pending the confirmation of a large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Anti-proliferative activities of sinigrin on carcinogen-induced hepatotoxicity in rats by Jie M1, Cheung WM1, Yu V1, Zhou Y1, Tong PH1, Ho JW. (PubMed)
(2) Are cell number and cell proliferation risk factors for cancer? by Albanes D1, Winick M. (PubMed)
Sinigrin may be the next-generation natural and bioactive compound processed an antiproliferative activity against the progression of cancer, according to studies.
In cancer, antiproliferation is a process in which the cancer cells are killed or limited to grow through many mechanisms, including the use of chemo drugs.
From the immune perspective, anti-proliferation can be carried out by activating the genes associated with cancer suppression, programming cell death,.... and cell cycle arrest.
A suppressive gene, such as pro-apoptotic p53 induces cancer cell death through cell cycle arrest. In other words, the gene inhibits tumor growth by interrupting the cancer cell cycle division.
The programmed cell death gene, such as BCL-2 induce cell death by either inducing or inhibiting apoptosis. In other words, If cells are no longer needed or damaged, activating an intracellular death program will cause cell death.
In phytochemicals, anti-proliferation can also be carried out by antioxidants in which they stimulate the free radicals overexpression to induce toxicity to tumor cells without causing harm to the nearby healthy cells.
Some cancers can stimulate the production of a new blood vessel for cancer cells to grow and others can make enzymes that break down normal cells and tissues as they grow.
Dr. Albanes D, in the study of cell proliferation as a major risk factor for cancer, said, "Caloric restriction strongly inhibits the development of neoplasia in rodents, and there is evidence of a positive relationship between cancer and body weight in humans".
And, "A recent link between adult stature and cancer incidence similarly implicates a lasting effect for growth and possibly for early nutrition in carcinogenesis. It is postulated that cancer risk is proportional to the number of proliferating cells, which in turn depends on both the number of cells and the rate of cell division within the tissue".
Sinigrin is a phytochemical glucosinolate, belonging to the family of glucosides found abundantly in Brussels sprouts, broccoli, the seeds of black mustard, etc.
Researchers on finding a bioactive compound for the treatment of liver cancer, one of the leading causes of cancer death worldwide. investigated the anti-proliferative activity of sinigrin, the major ingredient present in Brassica nigra.
In a model of carcinogen-induced hepatotoxicity in rats, the selected animals were orally administered with sinigrin on a daily basis for three months before sacrifice.
During the experiment, the injection of sinigrin significantly inhibited the proliferation of liver tumor cells, observed by the reduction of the number of surface tumors in the rat liver.
Sinigrin induced apoptosis of liver cancer cells by exhibiting the expression of a protein associated with tumor suppression in the host rats, namely, the p53.
Furthermore, the application of sinigrin-induced cancer apoptosis by stimulating the production of a protein involved in cell death programming and a gene involved in cellular differentiation.
Interestingly, in the additional analysis of the sinigrin anti-liver cancer activity, researchers showed that the bioactive compound not only inhibits cancer cells from proliferation through cell cycle arrest but also restores liver function without inducing liver toxicity.
The results strongly suggested that sinigrin processed significant anti-liver cancer properties via several genes and pathways.
Dr. Jie M, the lead scientist wrote in the final report, "Sinigrin exerts important anti-proliferative activities in carcinogen-induced hepatocarcinogenesis in rats, and highlights the potential of sinigrin as an anti-cancer agent for liver cancer".
Taken altogether, sinigrin found in Brassica nigra may be considered a functional supplement for the prevention and treatment of liver cancer, pending the confirmation of a large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Anti-proliferative activities of sinigrin on carcinogen-induced hepatotoxicity in rats by Jie M1, Cheung WM1, Yu V1, Zhou Y1, Tong PH1, Ho JW. (PubMed)
(2) Are cell number and cell proliferation risk factors for cancer? by Albanes D1, Winick M. (PubMed)
#Phytochemical 3,3'-#Diindolylmethane Inhibits #GastrointestinalCancer by Acting Upon Several Cellular and Molecular Processes
Kyle J. Norton
Scientists may have found a bioactive ingredient for the treatment of gastrointestinal cancer with no side effects, according to studies.
Gastrointestinal (GI) cancer is a group of cancers, affecting the digestive system, including esophagus, gallbladder & biliary tract, liver, pancreas, stomach, small intestine, bowel, and anus
The digestive system consists of the gastrointestinal tract and other parts of the accessory organs of digestion including the tongue, salivary glands, pancreas, liver, and gallbladder), involved in the function of breaking down food into smaller and smaller components then absorbed before passing them as nutrients and fluids to the body.
Most cases of gastrointestinal cancer start in the cells on the surface of the inner lining tissues, depending on the location of the affected organs.
At the early stage, most patients are asymptomatic due to the small size of the tumor. However, at the later stage, after penetrating into deeper layers of the organ, cancer cells can travel through blood and fluids circulation to infect other healthy tissues or organs, leading to secondary metastasis.
At this stage, besides sharing the general symptoms of other types of cancer, gastrointestinal cancer also cause symptoms of severe pain and bleeding due to the overgrowth of tumor size that has suppressed the nearby blood vessels and nerve cells.
The exact causes of gastrointestinal cancer are not identified. However, genetic preposition, unhealthy lifestyle and medical conditions are some of the prevalent risks of the disease.
Some researchers suggested that a poor diet may have a strong implication on the incidence of gastrointestinal cancer.
Dr. Reilly T. Enos, the lead scientist said, "High-fat-diet (HFD) consumption is associated with colon cancer risk".
And, "HFDs with the highest SF content had the greatest concentration of Muc2. Our data suggest that high dietary SF is protective in the AOM/DSS model of colon cancer, which may be due, at least in part, to the ability of SF to maintain intestinal barrier integrity through increased colonic Muc2".
With an aim to find a natural compound for the treatment of gastrointestinal cancers, researchers examined the 3,3'-Diindolylmethane (DIM) activity against effective gastrointestinal cancers.
In vivo and vitro, injection of the DIM acted upon several cellular and molecular processes in gastrointestinal cancer cells.
In cancer cells apoptosis, DIM initiated production reactive oxygen species (ROS) in generating stress, triggering DNA damage by increasing the cytotoxicity.
In angiogenesis, DIM inhibited the protein associated with the generation of a new blood vessel for cell survival and proliferation.
In cell cycle regulation, DIM deactivated the expression of protein kinases which play critical roles in cancer cell division.
Furthermore, DIM triggers cellular endoplasmic reticulum (ER) stress and apoptosis within the cancer cells.
In autophagy, DIM inhibited autophagy that leads to cell death.
In metastasis, DIM inhibited the growth of human cancer cells by interfering with multiple signaling pathways, involved restraining invasion, migration, and promoting apoptosis.
Furthermore, DIM used combined with conventional chemo drugs or therapeutic chemicals increased the efficacy of other drugs for the treatment of gastrointestinal cancer.
Taken together, 3,3'-Diindolylmethane derived from the digestion of indole-3-carbinol may be considered a supplement for the prevention and treatment of gastrointestinal cancers, pending to the confirmation of the larger sample size and multicenter human study.
Intake of 3,3'-diindolylmethane in form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cellular and Molecular Mechanisms of 3,3'-Diindolylmethane in Gastrointestinal Cancer by Kim SM. (PubMed)
Scientists may have found a bioactive ingredient for the treatment of gastrointestinal cancer with no side effects, according to studies.
Gastrointestinal (GI) cancer is a group of cancers, affecting the digestive system, including esophagus, gallbladder & biliary tract, liver, pancreas, stomach, small intestine, bowel, and anus
The digestive system consists of the gastrointestinal tract and other parts of the accessory organs of digestion including the tongue, salivary glands, pancreas, liver, and gallbladder), involved in the function of breaking down food into smaller and smaller components then absorbed before passing them as nutrients and fluids to the body.
Most cases of gastrointestinal cancer start in the cells on the surface of the inner lining tissues, depending on the location of the affected organs.
At the early stage, most patients are asymptomatic due to the small size of the tumor. However, at the later stage, after penetrating into deeper layers of the organ, cancer cells can travel through blood and fluids circulation to infect other healthy tissues or organs, leading to secondary metastasis.
At this stage, besides sharing the general symptoms of other types of cancer, gastrointestinal cancer also cause symptoms of severe pain and bleeding due to the overgrowth of tumor size that has suppressed the nearby blood vessels and nerve cells.
The exact causes of gastrointestinal cancer are not identified. However, genetic preposition, unhealthy lifestyle and medical conditions are some of the prevalent risks of the disease.
Some researchers suggested that a poor diet may have a strong implication on the incidence of gastrointestinal cancer.
Dr. Reilly T. Enos, the lead scientist said, "High-fat-diet (HFD) consumption is associated with colon cancer risk".
And, "HFDs with the highest SF content had the greatest concentration of Muc2. Our data suggest that high dietary SF is protective in the AOM/DSS model of colon cancer, which may be due, at least in part, to the ability of SF to maintain intestinal barrier integrity through increased colonic Muc2".
With an aim to find a natural compound for the treatment of gastrointestinal cancers, researchers examined the 3,3'-Diindolylmethane (DIM) activity against effective gastrointestinal cancers.
In vivo and vitro, injection of the DIM acted upon several cellular and molecular processes in gastrointestinal cancer cells.
In cancer cells apoptosis, DIM initiated production reactive oxygen species (ROS) in generating stress, triggering DNA damage by increasing the cytotoxicity.
In angiogenesis, DIM inhibited the protein associated with the generation of a new blood vessel for cell survival and proliferation.
In cell cycle regulation, DIM deactivated the expression of protein kinases which play critical roles in cancer cell division.
Furthermore, DIM triggers cellular endoplasmic reticulum (ER) stress and apoptosis within the cancer cells.
In autophagy, DIM inhibited autophagy that leads to cell death.
In metastasis, DIM inhibited the growth of human cancer cells by interfering with multiple signaling pathways, involved restraining invasion, migration, and promoting apoptosis.
Furthermore, DIM used combined with conventional chemo drugs or therapeutic chemicals increased the efficacy of other drugs for the treatment of gastrointestinal cancer.
Taken together, 3,3'-Diindolylmethane derived from the digestion of indole-3-carbinol may be considered a supplement for the prevention and treatment of gastrointestinal cancers, pending to the confirmation of the larger sample size and multicenter human study.
Intake of 3,3'-diindolylmethane in form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cellular and Molecular Mechanisms of 3,3'-Diindolylmethane in Gastrointestinal Cancer by Kim SM. (PubMed)
#FermentedCucumbers Exhibit Probiotic Properties in the Improvement of the Digestive Health, Researchers Find
Kyle J. Norton
Scientists may have found a bioactive ingredient for the prevention and treatment of neurodegeneration with no side effects, according to studies.
Probiotics are live bacteria and yeasts that play an essential role in the improvement of digestive functioning.
In other words, probiotics balanced the ratio of the gut microbiota by improving the levels of healthy organisms in the gut, particularly in people who are taking antibiotics, leading to the optimization of the digestive system in the absorption of nutrients for the body's needs such as supplying essential nutrients, synthesizing vitamin K, aiding in the digestion of cellulose, and promoting angiogenesis and enteric nerve function.
Where gut microbiota is the complex community of microorganisms that live in our gastrointestinal tracts.
Microbial imbalance or dysbiosis-induced intestinal inflammation as a result of overexpression of bad organisms in the gut has been found to utilize a complex arsenal of virulence factors to colonize and persist in the intestine, implicating the development of intestinal diseases.
Some virulence factors such as the genotoxin colibactin, produced by overexpression of bad bacteria in the gut were found to promote colorectal cancer and chronic intestinal inflammatory diseases.
Dr. Yu-Jie Zhang, the lead scientist in the examined the importance of gut bacteria on Human Health wrote, "Gut bacteria are an important component of the microbiota ecosystem in the human gut, which is colonized by 1014 microbes, ten times more than the human cells".
And, " they (imbalanced ratio of gut microbiota) can also be potentially harmful due to the change of their composition when the gut ecosystem undergoes abnormal changes in the light of the use of antibiotics, illness, stress, aging, bad dietary habits, and lifestyle. Dysbiosis of the gut bacteria communities can cause many chronic diseases, such as inflammatory bowel disease, obesity, cancer, and autism".
The cucumber plant is a species of Cucumis Sativus, belongs to the family Cucurbitaceae, and is native to Western Asia. It is a creeping vine with roots in the ground and grows up with the support of frames.
With an aim to find potential and natural compounds for the improvement of digestive health, researchers investigation the probiotic activity of cucumber.
According to the novel strain of lactic acid bacterium isolated from fermented cucumber, fermented carbohydrates such as sucrose, dextrose, and arabinose showed a significant gastroprotective effect against antibiotics, including ciprofloxacin, kanamycin, and vancomycin.
Furthermore, the isolate displayed potential probiotic properties in the improvement of the digestive health observed by hydrophobicity, autoaggregation, coaggregation, and in vitro cell adhesion ability.
Moreover, the isolate also exhibited resistance against bad bacteria and simulated gastric juice at pH 3.0.
Based on the findings researchers suggested that a novel strain of lactic acid bacterium isolated from fermented cucumber protected the digestive tract against the injection of antibiotics, inhibited the production of bad bacteria such as gram-positive bacterial and utilized the effects of prebiotics such as inulin and raffinose.
Dr. Shukla R, the lead scientist said, " These results indicate both probiotic property and the glucan-sucrase-producing ability of P. pentosaceus CRAG3".
In vitro, in the evaluation of the probiotic potentials of three Bacillus strains 437F, 1630F, and 1020G obtained from the traditional pickle researchers found that
* All strains only showed high acid, and bile tolerance but also exhibited antagonistic activity against various pathogens.
* All strains exhibited antioxidant activity, auto- and co-aggregation ability and surface hydrophobicity and attachment capacity against the Caco-2 cells were similar to those of well-known probiotic strains.
* All strains are safe without causing harm to healthy colon cells.
Based on the findings, researchers said, "With respect to their characteristics and safety aspect, these Bacillus species may have the potential to consider as probiotics for animal and/or human applications".
Taken altogether, cucumber may be considered supplements for the protection of digestive functioning, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Probiotic Potential of Pediococcus pentosaceus CRAG3: A New Isolate from Fermented Cucumber by Shukla R1, Goyal A. (PubMed)
(2) Three novel Bacillus strains from a traditional lacto-fermented pickle as potential probiotics by Talebi S1, Makhdoumi A1, Bahreini M1, Matin MM1,2, Moradi HS. (PubMed)
(3) Impacts of Gut Bacteria on Human Health and Diseases by Yu-Jie Zhang,1 Sha Li,2 Ren-You Gan,3 Tong Zhou,1 Dong-Ping Xu,1 and Hua-Bin Li1. (PubMed)
Scientists may have found a bioactive ingredient for the prevention and treatment of neurodegeneration with no side effects, according to studies.
Probiotics are live bacteria and yeasts that play an essential role in the improvement of digestive functioning.
In other words, probiotics balanced the ratio of the gut microbiota by improving the levels of healthy organisms in the gut, particularly in people who are taking antibiotics, leading to the optimization of the digestive system in the absorption of nutrients for the body's needs such as supplying essential nutrients, synthesizing vitamin K, aiding in the digestion of cellulose, and promoting angiogenesis and enteric nerve function.
Where gut microbiota is the complex community of microorganisms that live in our gastrointestinal tracts.
Microbial imbalance or dysbiosis-induced intestinal inflammation as a result of overexpression of bad organisms in the gut has been found to utilize a complex arsenal of virulence factors to colonize and persist in the intestine, implicating the development of intestinal diseases.
Some virulence factors such as the genotoxin colibactin, produced by overexpression of bad bacteria in the gut were found to promote colorectal cancer and chronic intestinal inflammatory diseases.
Dr. Yu-Jie Zhang, the lead scientist in the examined the importance of gut bacteria on Human Health wrote, "Gut bacteria are an important component of the microbiota ecosystem in the human gut, which is colonized by 1014 microbes, ten times more than the human cells".
And, " they (imbalanced ratio of gut microbiota) can also be potentially harmful due to the change of their composition when the gut ecosystem undergoes abnormal changes in the light of the use of antibiotics, illness, stress, aging, bad dietary habits, and lifestyle. Dysbiosis of the gut bacteria communities can cause many chronic diseases, such as inflammatory bowel disease, obesity, cancer, and autism".
The cucumber plant is a species of Cucumis Sativus, belongs to the family Cucurbitaceae, and is native to Western Asia. It is a creeping vine with roots in the ground and grows up with the support of frames.
With an aim to find potential and natural compounds for the improvement of digestive health, researchers investigation the probiotic activity of cucumber.
According to the novel strain of lactic acid bacterium isolated from fermented cucumber, fermented carbohydrates such as sucrose, dextrose, and arabinose showed a significant gastroprotective effect against antibiotics, including ciprofloxacin, kanamycin, and vancomycin.
Furthermore, the isolate displayed potential probiotic properties in the improvement of the digestive health observed by hydrophobicity, autoaggregation, coaggregation, and in vitro cell adhesion ability.
Moreover, the isolate also exhibited resistance against bad bacteria and simulated gastric juice at pH 3.0.
Based on the findings researchers suggested that a novel strain of lactic acid bacterium isolated from fermented cucumber protected the digestive tract against the injection of antibiotics, inhibited the production of bad bacteria such as gram-positive bacterial and utilized the effects of prebiotics such as inulin and raffinose.
Dr. Shukla R, the lead scientist said, " These results indicate both probiotic property and the glucan-sucrase-producing ability of P. pentosaceus CRAG3".
In vitro, in the evaluation of the probiotic potentials of three Bacillus strains 437F, 1630F, and 1020G obtained from the traditional pickle researchers found that
* All strains only showed high acid, and bile tolerance but also exhibited antagonistic activity against various pathogens.
* All strains exhibited antioxidant activity, auto- and co-aggregation ability and surface hydrophobicity and attachment capacity against the Caco-2 cells were similar to those of well-known probiotic strains.
* All strains are safe without causing harm to healthy colon cells.
Based on the findings, researchers said, "With respect to their characteristics and safety aspect, these Bacillus species may have the potential to consider as probiotics for animal and/or human applications".
Taken altogether, cucumber may be considered supplements for the protection of digestive functioning, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Probiotic Potential of Pediococcus pentosaceus CRAG3: A New Isolate from Fermented Cucumber by Shukla R1, Goyal A. (PubMed)
(2) Three novel Bacillus strains from a traditional lacto-fermented pickle as potential probiotics by Talebi S1, Makhdoumi A1, Bahreini M1, Matin MM1,2, Moradi HS. (PubMed)
(3) Impacts of Gut Bacteria on Human Health and Diseases by Yu-Jie Zhang,1 Sha Li,2 Ren-You Gan,3 Tong Zhou,1 Dong-Ping Xu,1 and Hua-Bin Li1. (PubMed)
#Phytochemical #Lycopene Protects the Bone Density Against the Onset of Osteoporopsis, Researchers Find
Kyle J. Norton
The osteoclast is a type of cell differentiated from another type of cell called a macrophage that breaks down the bone which leads to bone resorption.
In patients with osteoporosis, this balance shifts in favor of osteoclasts compared to those of osteoblasts.
In other words, in osteoporotic patients, bone resorption is far more exceedingly to bone formation.
Furthermore, the imbalance of osteoclasts and osteoblasts also is found in patients with Paget's disease, rheumatoid arthritis, osteopetrosis, periodontal disease, and bone cancer metastases.
Osteoclastogenesis is a procedure that included many stages, that interferes with the specific stage of the process, diseases associated with imbalanced osteoclasts, and osteoblast that may be preventable in the future.
Dr. Tobias Braun wrote, "Bone loss in RA patients is a frequent and clinically serious event. Considering bone remodeling in general, the balance between bone formation and bone resorption determines the net effect. In the past decade, significant gains in knowledge about the role of bone resorption during chronic erosive arthritis have been made. There is good evidence that inflammation itself triggers bone resorption by osteoclasts ".
And, "Pro-inflammatory cytokines are potent mediators of bone loss. These cytokines act both, directly and indirectly, to enhance osteoclastogenesis in the inflamed joint and systemic bone: first, many pro-inflammatory cytokines can alter the RANKL/OPG ratio in mesenchymal cells, such as osteoblasts and fibroblasts; second, some cytokines, such as M-CSF and RANKL, also directly affect osteoclast differentiation, survival, and activity".
Lycopene is a phytochemical in the class of carotenoids, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,
Tomatoes provide about 80% of the lycopene in the world's diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.
With an aim to find a potential phytochemical to protect bone density, researchers examined the osteoclastogenetic effect of lycopene.
According to the tested differentiation
* The ingestion of lycopene-containing products such as tomato showed a significant effect on decreased osteoclast differentiation. In other words, lycopene protected bone density by inhibiting bone reabsorption.
* Lycopene not only did not affect cell density/survival but also protected the bone by decreasing the calcium-phosphate resorption.
* Lycopene also acted as an MEK signaling inhibitor to promote bone formation.
* Additionally, lycopene also promoted an anabolic state of bone metabolism, through the regulation of the protein kinase C pathway associated with osteoclast formation and function potentially.
Based on the findings, lycopene protects bone mineral density by inhibiting the expression of osteoclastogenesis.
Researchers after taking into account co and confounders said, "This information might be relevant for the prevention and delay in the progression of osteolytic bone conditions".
Taken together, lycopene found in tomatoes may be considered supplements for the promotion of osteoclastogenesis, pending the confirmation of the larger sample size and multicenter human study.
Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Modulation of human osteoclastogenesis and osteoblastogenesis by lycopene by Costa-Rodrigues J1, Fernandes MH2, Pinho O3, Monteiro PRR. (PubMed)
(2) Lycopene treatment against loss of bone mass, microarchitecture, and strength in relation to regulatory mechanisms in a postmenopausal osteoporosis model by Ardawi MM1, Badawoud MH2, Hassan SM2, Rouzi AA3, Ardawi JMS4, AlNosani NM4, Qari MH5, Mousa SA6. (PubMed)
(3) Positive regulators of osteoclastogenesis and bone resorption in rheumatoid arthritis by Tobias Braun1 and Jochen Zwerina. (PMC)
The osteoclast is a type of cell differentiated from another type of cell called a macrophage that breaks down the bone which leads to bone resorption.
In patients with osteoporosis, this balance shifts in favor of osteoclasts compared to those of osteoblasts.
In other words, in osteoporotic patients, bone resorption is far more exceedingly to bone formation.
Furthermore, the imbalance of osteoclasts and osteoblasts also is found in patients with Paget's disease, rheumatoid arthritis, osteopetrosis, periodontal disease, and bone cancer metastases.
Osteoclastogenesis is a procedure that included many stages, that interferes with the specific stage of the process, diseases associated with imbalanced osteoclasts, and osteoblast that may be preventable in the future.
Dr. Tobias Braun wrote, "Bone loss in RA patients is a frequent and clinically serious event. Considering bone remodeling in general, the balance between bone formation and bone resorption determines the net effect. In the past decade, significant gains in knowledge about the role of bone resorption during chronic erosive arthritis have been made. There is good evidence that inflammation itself triggers bone resorption by osteoclasts ".
And, "Pro-inflammatory cytokines are potent mediators of bone loss. These cytokines act both, directly and indirectly, to enhance osteoclastogenesis in the inflamed joint and systemic bone: first, many pro-inflammatory cytokines can alter the RANKL/OPG ratio in mesenchymal cells, such as osteoblasts and fibroblasts; second, some cytokines, such as M-CSF and RANKL, also directly affect osteoclast differentiation, survival, and activity".
Lycopene is a phytochemical in the class of carotenoids, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,
Tomatoes provide about 80% of the lycopene in the world's diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.
With an aim to find a potential phytochemical to protect bone density, researchers examined the osteoclastogenetic effect of lycopene.
According to the tested differentiation
* The ingestion of lycopene-containing products such as tomato showed a significant effect on decreased osteoclast differentiation. In other words, lycopene protected bone density by inhibiting bone reabsorption.
* Lycopene not only did not affect cell density/survival but also protected the bone by decreasing the calcium-phosphate resorption.
* Lycopene also acted as an MEK signaling inhibitor to promote bone formation.
* Additionally, lycopene also promoted an anabolic state of bone metabolism, through the regulation of the protein kinase C pathway associated with osteoclast formation and function potentially.
Based on the findings, lycopene protects bone mineral density by inhibiting the expression of osteoclastogenesis.
Researchers after taking into account co and confounders said, "This information might be relevant for the prevention and delay in the progression of osteolytic bone conditions".
Taken together, lycopene found in tomatoes may be considered supplements for the promotion of osteoclastogenesis, pending the confirmation of the larger sample size and multicenter human study.
Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Modulation of human osteoclastogenesis and osteoblastogenesis by lycopene by Costa-Rodrigues J1, Fernandes MH2, Pinho O3, Monteiro PRR. (PubMed)
(2) Lycopene treatment against loss of bone mass, microarchitecture, and strength in relation to regulatory mechanisms in a postmenopausal osteoporosis model by Ardawi MM1, Badawoud MH2, Hassan SM2, Rouzi AA3, Ardawi JMS4, AlNosani NM4, Qari MH5, Mousa SA6. (PubMed)
(3) Positive regulators of osteoclastogenesis and bone resorption in rheumatoid arthritis by Tobias Braun1 and Jochen Zwerina. (PMC)
#Navy Bean Inhibits Parameters Associated with a Reduced Risk of #CardiovascularDisease, Researchers Find
Kyle J. Norton
Cardiovascular disease (CVD) is a class of diseases involved in the heart or blood vessels. In other words, CVD includes heart disease and stroke.
Heart Disease is a medical condition associated with reduced function of the heart in pumping blood to the body through its blood vessels.
In the US, heart disease causes the death of approximately 610,000 Americans every year. More precisely 1 in every 4 deaths in the US is associated with heart disease.
Most cases of heart disease are caused by high blood pressure that contributes to the hardening of the arteries, and high levels of bad cholesterol (LDL) that cause the build-up of plaque in the arteries.
High levels of bad cholesterol (LDL) have been found epidemiologically, associated with an uncontrolled diet with high levels of saturated fat and trans fat, which lead to the formation of atherosclerosis lesions and eventually arterial blockage.
In other words, anything that serves to damage the inner lining of blood vessels and impedes the transportation of oxygen and nutrition to the heart is a risk of heart disease.
A stroke is caused by the interruption or reduction of blood supply to part of the brain that deprives the brain tissue of oxygen and nutrients, leading to the death of brain cells.
According to the statistics, every year, more than 795,000 people in the US have a stroke, including 610,000 cases of new strokes.
Believe it or not, 1 of 4 cases of stroke are in people who have had a previous stroke.
There are similar causes of stroke and heart disease, but in stroke, the result is more severe. Any delay in rescuing will result in the death of the victim.
The small, white navy bean, also called pea bean or haricot, popular in both dry and green forms, is very popular in Britain and the US, native to Peru. The legume is now grown and consumed across the world, due to its numerous health benefits.
With an aim to find a potential ingredient for the prevention and treatment of cardiovascular disease, researchers examined the navy beans and rice bran effect on regulating blood lipids in adults and children.
The pilot, randomized-controlled, clinical trial included 38 children (10 ± 0.8 years old) with abnormal cholesterol who consumed a snack for 4 weeks containing either: no navy bean or rice bran (control); 17.5 g/day cooked navy bean powder; 15 g/day heat-stabilized rice bran; or 9 g/day navy beans and 8 g/day rice bran.
According to the analysis of the plasma metabolites extracted, navy bean and/or rice bran consumption influenced 71 plasma compounds compared to the control (p ≤ 0.05), with lipids representing 46% of the total plasma metabolome.
In other words, navy bean intake causes significant changes of 18 plasma lipids compared to only 10 plasma lipids for the rice bran group and 48 lipids compared to only 40 in the rice bran group compared to baseline.
More precisely, the intake of navy beans had a positive impact on blood lipid metabolism in reducing CVD risk in children.
Additional differentiation of the navy bean anti hyper cholesterol activity, researchers found that the efficacy of navy bean was attributed to the decrease of free fatty acids associated with metabolic diseases (palmitate and arachidonate) and an increase of the relative abundance of endogenous anti-inflammatory lipids.
Based on the results, researchers said, " Findings from this pilot study support the need for investigating the effects of these foods for longer durations to reduce CVD risk".
Taken together, the navy bean may be considered a remedy for the prevention and treatment of cardiovascular disease caused by high blood cholesterol, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Navy Bean and Rice Bran Intake Alters the Plasma Metabolome of Children at Risk for Cardiovascular Disease by Li KJ1, Borresen EC1, Jenkins-Puccetti N2, Luckasen G2, Ryan EP. (PubMed)
(2) Heart Diseases- Causes, Symptoms, Types, Preventions & Treatments by Kyle J. Norton
(3) Stroke -- The Causes by Kyle J. Norton
Cardiovascular disease (CVD) is a class of diseases involved in the heart or blood vessels. In other words, CVD includes heart disease and stroke.
Heart Disease is a medical condition associated with reduced function of the heart in pumping blood to the body through its blood vessels.
In the US, heart disease causes the death of approximately 610,000 Americans every year. More precisely 1 in every 4 deaths in the US is associated with heart disease.
Most cases of heart disease are caused by high blood pressure that contributes to the hardening of the arteries, and high levels of bad cholesterol (LDL) that cause the build-up of plaque in the arteries.
High levels of bad cholesterol (LDL) have been found epidemiologically, associated with an uncontrolled diet with high levels of saturated fat and trans fat, which lead to the formation of atherosclerosis lesions and eventually arterial blockage.
In other words, anything that serves to damage the inner lining of blood vessels and impedes the transportation of oxygen and nutrition to the heart is a risk of heart disease.
A stroke is caused by the interruption or reduction of blood supply to part of the brain that deprives the brain tissue of oxygen and nutrients, leading to the death of brain cells.
According to the statistics, every year, more than 795,000 people in the US have a stroke, including 610,000 cases of new strokes.
Believe it or not, 1 of 4 cases of stroke are in people who have had a previous stroke.
There are similar causes of stroke and heart disease, but in stroke, the result is more severe. Any delay in rescuing will result in the death of the victim.
The small, white navy bean, also called pea bean or haricot, popular in both dry and green forms, is very popular in Britain and the US, native to Peru. The legume is now grown and consumed across the world, due to its numerous health benefits.
With an aim to find a potential ingredient for the prevention and treatment of cardiovascular disease, researchers examined the navy beans and rice bran effect on regulating blood lipids in adults and children.
The pilot, randomized-controlled, clinical trial included 38 children (10 ± 0.8 years old) with abnormal cholesterol who consumed a snack for 4 weeks containing either: no navy bean or rice bran (control); 17.5 g/day cooked navy bean powder; 15 g/day heat-stabilized rice bran; or 9 g/day navy beans and 8 g/day rice bran.
According to the analysis of the plasma metabolites extracted, navy bean and/or rice bran consumption influenced 71 plasma compounds compared to the control (p ≤ 0.05), with lipids representing 46% of the total plasma metabolome.
In other words, navy bean intake causes significant changes of 18 plasma lipids compared to only 10 plasma lipids for the rice bran group and 48 lipids compared to only 40 in the rice bran group compared to baseline.
More precisely, the intake of navy beans had a positive impact on blood lipid metabolism in reducing CVD risk in children.
Additional differentiation of the navy bean anti hyper cholesterol activity, researchers found that the efficacy of navy bean was attributed to the decrease of free fatty acids associated with metabolic diseases (palmitate and arachidonate) and an increase of the relative abundance of endogenous anti-inflammatory lipids.
Based on the results, researchers said, " Findings from this pilot study support the need for investigating the effects of these foods for longer durations to reduce CVD risk".
Taken together, the navy bean may be considered a remedy for the prevention and treatment of cardiovascular disease caused by high blood cholesterol, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Navy Bean and Rice Bran Intake Alters the Plasma Metabolome of Children at Risk for Cardiovascular Disease by Li KJ1, Borresen EC1, Jenkins-Puccetti N2, Luckasen G2, Ryan EP. (PubMed)
(2) Heart Diseases- Causes, Symptoms, Types, Preventions & Treatments by Kyle J. Norton
(3) Stroke -- The Causes by Kyle J. Norton
#Beet Inhibits Lipid Peroxidation Associated with a Reduced Risk of #Parkinson's Disease(PD), Researchers Show
Kyle J. Norton
Beet or beetroot may be considered as a functional food for reduced risk of early-onset and treatment of Parkinson's disease(PD), a recent study suggested.
Parkinson's disease (PD) is a condition of neurodegenerative disease that progressed over time caused by dysfunction of nerve cells involving motor functioning, including signs of tremor of the hands, arms, legs, jaw, and face. bradykinesia ......
Beet, best known as the beetroot or garden beet and belonging to the amaranth family, is a perennial plant with leafy stems growing to 1–2 m tall.
According to the MVP Samaj's College of Pharmacy, in the animal model of PD induced by administration of reserpine (5 mg/kg/day, i.p for 5 consecutive days), haloperidol (1 mg/kg, i.p.), and tacrine (2.5 mg/kg, i.p.), rats fed with methanolic extract of Beta vulgaris (MEBV)at doses of 100, 200, and 300 mg/kg showed a significantly reduced the intensity of muscular rigidity, duration of catalepsy, akinesia, the number of tremors, dis-proportionally.
Concentrations of 200, and 300 mg/kg extract exhibited the most effects compared to dose of 100mg/kg.
Furthermore, at the higher doses, treatment animals also exerted an improvement in locomotor functioning and grip strength analyzed by MEBV.
The study also indicated that the efficacy of beet methanolic extract may be attributed to the increase of antioxidants in inhibiting the production of lipid peroxidation, an important process in causing cell dysfunction in PD patients.
Not only that, but injection of the extract also restored the defensive antioxidant enzymes SOD and CAT in the rat brain.
Dr. The lead author said, "The mechanism of protection may be due to augmentation of cellular antioxidants".
Other researchers also suggested that intake of beet juice may improve the blood circulation of the brain's white matter of the frontal lobes associated with the development of dementia and other cognitive conditions, including the risk of PD and PD progression in older adults.
Dr. Gary Miller,, the lead author of this study said, "I think these results are consistent and encouraging - that a good diet consisting of a lot of fruits and vegetables can contribute to overall good health".
Collectively, the evidence suggested that beet methanolic extract or nitrate-rich beet juice may have a profound effect on the reduced prevalence of early-onset and progression of Parkinson's disease (PD) and may be considered a functional food. for these purposes.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Sources
(1) Neuroprotective potential of Beta vulgaris L. in Parkinson's disease by Nade VS1, Kawale LA1, Zambre SS1, Kapure AB1.(PubMed)
(2) Daily Dose Of Beet Juice Promotes Brain Health In Older Adults
Published Thursday 4 November 2010 By Janet Epping(Medical news today)
Beet or beetroot may be considered as a functional food for reduced risk of early-onset and treatment of Parkinson's disease(PD), a recent study suggested.
Parkinson's disease (PD) is a condition of neurodegenerative disease that progressed over time caused by dysfunction of nerve cells involving motor functioning, including signs of tremor of the hands, arms, legs, jaw, and face. bradykinesia ......
Beet, best known as the beetroot or garden beet and belonging to the amaranth family, is a perennial plant with leafy stems growing to 1–2 m tall.
According to the MVP Samaj's College of Pharmacy, in the animal model of PD induced by administration of reserpine (5 mg/kg/day, i.p for 5 consecutive days), haloperidol (1 mg/kg, i.p.), and tacrine (2.5 mg/kg, i.p.), rats fed with methanolic extract of Beta vulgaris (MEBV)at doses of 100, 200, and 300 mg/kg showed a significantly reduced the intensity of muscular rigidity, duration of catalepsy, akinesia, the number of tremors, dis-proportionally.
Concentrations of 200, and 300 mg/kg extract exhibited the most effects compared to dose of 100mg/kg.
Furthermore, at the higher doses, treatment animals also exerted an improvement in locomotor functioning and grip strength analyzed by MEBV.
The study also indicated that the efficacy of beet methanolic extract may be attributed to the increase of antioxidants in inhibiting the production of lipid peroxidation, an important process in causing cell dysfunction in PD patients.
Not only that, but injection of the extract also restored the defensive antioxidant enzymes SOD and CAT in the rat brain.
Dr. The lead author said, "The mechanism of protection may be due to augmentation of cellular antioxidants".
Other researchers also suggested that intake of beet juice may improve the blood circulation of the brain's white matter of the frontal lobes associated with the development of dementia and other cognitive conditions, including the risk of PD and PD progression in older adults.
Dr. Gary Miller,, the lead author of this study said, "I think these results are consistent and encouraging - that a good diet consisting of a lot of fruits and vegetables can contribute to overall good health".
Collectively, the evidence suggested that beet methanolic extract or nitrate-rich beet juice may have a profound effect on the reduced prevalence of early-onset and progression of Parkinson's disease (PD) and may be considered a functional food. for these purposes.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Sources
(1) Neuroprotective potential of Beta vulgaris L. in Parkinson's disease by Nade VS1, Kawale LA1, Zambre SS1, Kapure AB1.(PubMed)
(2) Daily Dose Of Beet Juice Promotes Brain Health In Older Adults
Published Thursday 4 November 2010 By Janet Epping(Medical news today)
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