Kyle J. Norton
Andrographis paniculata is also known as Andrographis, is a herbaceous plant, genus Andrographis, belonging to the family Acanthaceae, native to India and Sri Lanka, used in traditional Siddha and Ayurvedic in treating the common cold, flu, upper respiratory infections, infectious diseases, diarrhea, dysentery, cholera, pneumonia,.. .....
Wound healing is a natural response to restore injured tissues.
Andrographis paniculata leaf showed to process a significant wound healing effect in restoring injured tissues, a mentioned institute suggested.
According to the Universiti Teknologi MARA, the topical application of Andrographis paniculata exerted a strong effect on the rate of wound enclosure with markedly less scar width and contained large amounts of fibroblast proliferation.
In a study of the wound created in four groups of rats in the posterior neck region. A blank placebo applied topically to the wounds of Group 1 and Groups 2 and 3 dressed with a placebo containing 5% and 10% extracts of A. paniculata, groups treated with topical showed a rate of wound healing significantly accelerated in the wound dressed compared to the placebo group.
The wound healing is also increased collagen and less formation of new blood vessels with the absence of inflammatory cells.
Another study, in the evaluation of the effects of andrographis wound healing activity of Swiss Wistar strain rats with either sex with topical application, 2%w/w ointment of ethanol extract and petroleum ether extract prepared in 2% w/w PEG-4000 in comparison to the left untreated control group, treatment groups showed a faster rate of complete healing in day 12 after topical application with wound contractions in petroleum ether extract, the ethanolic extract was at 10.17 and 16.33, respectively.
Dr. Arnabaditya Mohanty, the lead author in the joint study said, "Andrographis paniculate ethanolic extract possesses better wound healing property in comparison to control and also with petroleum ether extract".
Taken together, topical application of Andrographis paniculata leaf and extract may be used as a wound-healing agent in accelerated restored injured tissues with lesser scarring without induced adverse effects.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
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Sources
(1) Effect of Andrographis paniculata leaf extract on wound healing in rats by Al-Bayaty FH1, Abdulla MA, Abu Hassan MI, Ali HM.(PubMed) and(University of Malaya)
(2) Preliminary Pytochemical Screening and Wound Healing Activity of Andrographis Peniculata by Arnabaditya Mohanty1 , Dusmanta Kumar Pradhan1 , Manas Ranjan Mishra1 , Jitendra Kumar Sahoo1 , Ashutosh Mishra *2, Bankim Chan(Journal of Chemical and Pharmaceutical Research)
Tuesday, 15 August 2023
#Formula OptiBerry IH141 Including all Berries and Blueberry #Extract Process Superior Anti-Angiogenic Properties, Studies Find
Kyle J. Norton
According to studies, Bilberry may process a unique function in blocking the formation of new blood vessels to fuel tumor growth.
Angiogenesis is the development of new blood vessels from the existing vasculature. The process has occurred throughout life in humans in the form of health and disease.
Normal angiogenesis ensures that developing or healing tissues receive an adequate supply of nutrients,
In a tumor, the availability of nutrients is limited, therefore, for the tumor to survive and grow continuously, the tumor cells induce the formation of a new blood supply from the preexisting vasculature by stimulating the protein associated with the pro-angiogenesis and facilitation of angiogenesis, such as vascular endothelial growth factor.
In other words, if we can cut off the blood vessels that provide nutrients to the tumor, we may cure cancers.
Dr. Adair TH, the lead scientists in the investigation of the angiogenesis in diseases and cancer said, "Stimulation of angiogenesis can be therapeutic in ischemic heart disease, peripheral arterial disease, and wound healing. Decreasing or inhibiting angiogenesis can be therapeutic in cancer, ophthalmic conditions, rheumatoid arthritis, and other diseases".
And, "Capillaries grow and regress in healthy tissues according to functional dem bands. Exercise stimulates angiogenesis in skeletal muscle and heart. A lack of exercise leads to capillary regression. Capillaries grow in adipose tissue during weight gain and regress during weight loss.
The results strongly suggested that by allowing or blocking the growth of new blood vessels, angiogenesis may be used as a primary target for the treatment of chronic diseases and cancers
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The herbal plant has been used as foods and herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, psoriasis, diabetes, etc.
Researchers on finding a natural compound that blocks the progression of cancer examined the anti-angiogenic activity of berry anthocyanins.
Six berry extracts (wild blueberry, bilberry, cranberry, elderberry, raspberry seeds, and strawberry) included in the study were analyzed for the anti-angiogenic (the ability to reduce unwanted growth of blood vessels, which can lead to varicose veins and tumor formation) properties.
Formula OptiBerry IH141, including all berries used in the study, demonstrated superior anti-angiogenic properties compared to the other combinations tested.
OptiBerry significantly inhibited free radical and proinflammatory cytokines in the expression of VEGF (Vascular Endothelial Growth Factor) associated with the formation of the new blood vessels.
According to the Matrigel assay using human microvascular endothelial cells, OptiBerry reduced the new blood vessel formation by impairing angiogenesis.
Furthermore, endothelioma cells pretreated with OptiBerry showed a diminished ability to form hemangioma and markedly decreased tumor growth by more than 50% through its anti-angiogenic, and anti-carcinogenic properties.
In order to reveal more information about berry's anti-angiogenic activity to prevent and treat cancer, researchers investigated the six berry extracts (wild blueberry, bilberry, cranberry, elderberry, raspberry seed, and strawberry) and a grape seed proanthocyanidin extract (GSPE) against the formation of new blood vessels for cancer proliferation.
Wild bilberry and blueberry extracts possessed the highest antioxidant activity observed by the ORAC values compared to other berries.
In other words, wild bilberry and blueberry extracts inhibited the overexpression of free radicals and proinflammatory cytokines in stimulating the production of VEGF (Vascular Endothelial Growth Factor) in enhancing angiogenesis.
Interestingly, these activities of wild bilberry and blueberry extracts were not shared by other antioxidants such as alpha-tocopherol or GSPE but were commonly shared by pure flavonoids.
Taken together, bilberry used alone or combined with other berries may be considered functional remedies for the prevention of angiogenesis and treatment of cancer cell proliferation by stimulating the formation of a new blood vessel, pending the confirmation of large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Anti-angiogenic, antioxidant, and anti-carcinogenic properties of a novel anthocyanin-rich berry extract formula by Bagchi D1, Sen CK, Bagchi M, Atalay M. (PubMed)
(2) Anti-angiogenic property of edible berries by Roy S1, Khanna S, Alessio HM, Vider J, Bagchi D, Bagchi M, Sen CK. (PubMed)
(3) Chapter 1Overview of Angiogenesis by Adair TH, Montani JP.. (NCBI)
According to studies, Bilberry may process a unique function in blocking the formation of new blood vessels to fuel tumor growth.
Angiogenesis is the development of new blood vessels from the existing vasculature. The process has occurred throughout life in humans in the form of health and disease.
Normal angiogenesis ensures that developing or healing tissues receive an adequate supply of nutrients,
In a tumor, the availability of nutrients is limited, therefore, for the tumor to survive and grow continuously, the tumor cells induce the formation of a new blood supply from the preexisting vasculature by stimulating the protein associated with the pro-angiogenesis and facilitation of angiogenesis, such as vascular endothelial growth factor.
In other words, if we can cut off the blood vessels that provide nutrients to the tumor, we may cure cancers.
Dr. Adair TH, the lead scientists in the investigation of the angiogenesis in diseases and cancer said, "Stimulation of angiogenesis can be therapeutic in ischemic heart disease, peripheral arterial disease, and wound healing. Decreasing or inhibiting angiogenesis can be therapeutic in cancer, ophthalmic conditions, rheumatoid arthritis, and other diseases".
And, "Capillaries grow and regress in healthy tissues according to functional dem bands. Exercise stimulates angiogenesis in skeletal muscle and heart. A lack of exercise leads to capillary regression. Capillaries grow in adipose tissue during weight gain and regress during weight loss.
The results strongly suggested that by allowing or blocking the growth of new blood vessels, angiogenesis may be used as a primary target for the treatment of chronic diseases and cancers
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The herbal plant has been used as foods and herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, psoriasis, diabetes, etc.
Researchers on finding a natural compound that blocks the progression of cancer examined the anti-angiogenic activity of berry anthocyanins.
Six berry extracts (wild blueberry, bilberry, cranberry, elderberry, raspberry seeds, and strawberry) included in the study were analyzed for the anti-angiogenic (the ability to reduce unwanted growth of blood vessels, which can lead to varicose veins and tumor formation) properties.
Formula OptiBerry IH141, including all berries used in the study, demonstrated superior anti-angiogenic properties compared to the other combinations tested.
OptiBerry significantly inhibited free radical and proinflammatory cytokines in the expression of VEGF (Vascular Endothelial Growth Factor) associated with the formation of the new blood vessels.
According to the Matrigel assay using human microvascular endothelial cells, OptiBerry reduced the new blood vessel formation by impairing angiogenesis.
Furthermore, endothelioma cells pretreated with OptiBerry showed a diminished ability to form hemangioma and markedly decreased tumor growth by more than 50% through its anti-angiogenic, and anti-carcinogenic properties.
In order to reveal more information about berry's anti-angiogenic activity to prevent and treat cancer, researchers investigated the six berry extracts (wild blueberry, bilberry, cranberry, elderberry, raspberry seed, and strawberry) and a grape seed proanthocyanidin extract (GSPE) against the formation of new blood vessels for cancer proliferation.
Wild bilberry and blueberry extracts possessed the highest antioxidant activity observed by the ORAC values compared to other berries.
In other words, wild bilberry and blueberry extracts inhibited the overexpression of free radicals and proinflammatory cytokines in stimulating the production of VEGF (Vascular Endothelial Growth Factor) in enhancing angiogenesis.
Interestingly, these activities of wild bilberry and blueberry extracts were not shared by other antioxidants such as alpha-tocopherol or GSPE but were commonly shared by pure flavonoids.
Taken together, bilberry used alone or combined with other berries may be considered functional remedies for the prevention of angiogenesis and treatment of cancer cell proliferation by stimulating the formation of a new blood vessel, pending the confirmation of large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Anti-angiogenic, antioxidant, and anti-carcinogenic properties of a novel anthocyanin-rich berry extract formula by Bagchi D1, Sen CK, Bagchi M, Atalay M. (PubMed)
(2) Anti-angiogenic property of edible berries by Roy S1, Khanna S, Alessio HM, Vider J, Bagchi D, Bagchi M, Sen CK. (PubMed)
(3) Chapter 1Overview of Angiogenesis by Adair TH, Montani JP.. (NCBI)
Monday, 14 August 2023
#Herbal #Artichoke's Ethanolic #Extract Show An Inhibited Effect on Liver Oxidative Stress Markers Associated with the Onset of #LiverDiseases, According to Studies
Kyle J. Norton
The hepatoprotective or liver protective effect is an action that maintains the liver's healthy functioning against any harmful toxins.
The liver is the largest internal organ in the human body and the only organ which can regenerate itself. The liver is the first line of the bodily toxin defense by filtering the blood that comes from the digestive tract, before passing it to the rest of the body.
Furthermore, the liver also processes a function of detoxifying chemicals and metabolizes drugs.
Symptoms of liver diseases include jaundice, abdominal pain, swelling, swelling in the legs and ankles, itchy skin, dark urine, pale stool color, and a tendency to bruise easily.
If you experience some of the above symptoms, please make sure that you check with your doctor to rule out the possibility of liver disease.
Most cases of liver disease are associated with hepatitis viral infection and autoimmune diseases. However, excessive alcohol drinking has been found to induce alcoholic liver disease in many parts of Asia and America.
Dr. Suthat Liangpunsakul, the lead scientist, in the comparison of alcoholic disease in different regions, wrote, "Alcoholic liver diseases (ALD) comprise a spectrum of clinical disorders and changes in liver tissue that can be detected by pathology analysis. These range from steatosis to more severe signs and symptoms of liver disease associated with inflammation, such as those observed in patients with alcoholic hepatitis or cirrhosis".
And, " Inter-individual differences in susceptibility to the toxic effects of alcohol have been extensively studied—they include a pattern of alcohol consumption, sex, environmental factors (such as diet), and genetic factors, which vary widely among different parts of the world. ALD is becoming more common in many parts of Asia but is decreasing in Western Europe".
The results clearly and strongly suggested that reducing the intake of alcohol and following a healthy diet pattern is the best way to decrease the risk of liver diseases, including ALD.
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detox agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
Scientists on finding a natural ingredient that processes liver protective effects evaluated the preventive effects of ethanolic extract from artichoke against acute alcohol-induced liver injury in mice.
Selected male mice were treated with an ethanolic extract of artichoke (0.4, 0.8, and 1.6 g/kg body weight) by gavage once daily before administrated up to 40% alcohol (12 mL/kg body weight) orally 1 h after artichoke treatment for 10 consecutive days.
Injection of artichoke extract not only significantly prevented elevated levels of aspartate aminotransferase, alanine aminotransferase, and the liver oxidative stress markers but also reduced the levels of triglyceride, and total cholesterol.
Artichoke treatment mice also restored the levels of antioxidant enzymes which were reduced by the injection of alcohol.
According to the immunohistochemical analysis, artichoke also suppressed the levels of toll-like receptor (TLR) 4 which plays a critical role in the production of several pro-inflammatory, antiviral, and anti-bacterial cytokines and protein, nuclear factor-kappa B (NF-κB) associated with liver cells apoptosis in liver tissues.
The results indicated a liver protective activity in artichoke was attributed to the inhibition of the pro-inflammatory proteins in acute alcohol-induced liver injury mice.
In order to reveal more information about the liver protective effect of artichokes, researchers examined the herbal medicine against liver fibrosis, the main pathology of schistosomiasis, and its complications are the major cause of death in infected cases.
Mice selected for the study infected with Schistosoma mansoni (S. mansoni) were divided into 5 groups. The first three groups were given artichoke leaf extract (ALE), ALE + praziquantel (PZQ), and PZQ respectively. The 4th was a positive control and the 5th was the negative control group. and were compared to PZQ.
Injection of ALE and ALE + praziquantel (PZQ) caused a significant reduction of granuloma diameter, improvement of liver functions, and liver fibrosis.
Furthermore, ALE induced statistically significant changes in hepatic stellate cells (HSCs) distribution.
Moreover, ALE also reduced granuloma size by increasing HSCs recruitment inside granuloma and limited liver fibrosis by their inhibition in the peri- and inter-granuloma liver tissue.
Unfortunately, although, the herbal extract exerted a strong liver protective activity, it failed to treat S. mansoni infection.
Taken altogether, artichoke may be considered a functional remedy for the prevention and treatment of liver disease, pending the confirmation of large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Liver protective effects
(1) Protective Effects of Ethanolic Extracts from Artichoke, an Edible Herbal Medicine, against Acute Alcohol-Induced Liver Injury in Mice by Tang X1, Wei R2, Deng A3, Lei T. (PubMed)
(2) Artichoke leaf extract protects the liver of Schistosoma mansoni infected mice through modulation of hepatic stellate cell recruitment by Sharaf El-Deen SA1, Barakat RM2, Mohamed ASED. (PubMed)
(3) [Artichoke--the untapped potential of herbal medicine in the treatment of atherosclerosis and liver diseases].[Article in Polish] by Horoszkiewicz M1, Kulza M, Malinowska K, Woźniak A, Seńczuk-Przybyłowska M, Wachowiak A, Florek E.(PubMed)
(4) Alcoholic Liver Disease in Asia, Europe, and North America by Suthat Liangpunsakul, Paul Haber, and Geoff McCaughan. (PMC)
The hepatoprotective or liver protective effect is an action that maintains the liver's healthy functioning against any harmful toxins.
The liver is the largest internal organ in the human body and the only organ which can regenerate itself. The liver is the first line of the bodily toxin defense by filtering the blood that comes from the digestive tract, before passing it to the rest of the body.
Furthermore, the liver also processes a function of detoxifying chemicals and metabolizes drugs.
Symptoms of liver diseases include jaundice, abdominal pain, swelling, swelling in the legs and ankles, itchy skin, dark urine, pale stool color, and a tendency to bruise easily.
If you experience some of the above symptoms, please make sure that you check with your doctor to rule out the possibility of liver disease.
Most cases of liver disease are associated with hepatitis viral infection and autoimmune diseases. However, excessive alcohol drinking has been found to induce alcoholic liver disease in many parts of Asia and America.
Dr. Suthat Liangpunsakul, the lead scientist, in the comparison of alcoholic disease in different regions, wrote, "Alcoholic liver diseases (ALD) comprise a spectrum of clinical disorders and changes in liver tissue that can be detected by pathology analysis. These range from steatosis to more severe signs and symptoms of liver disease associated with inflammation, such as those observed in patients with alcoholic hepatitis or cirrhosis".
And, " Inter-individual differences in susceptibility to the toxic effects of alcohol have been extensively studied—they include a pattern of alcohol consumption, sex, environmental factors (such as diet), and genetic factors, which vary widely among different parts of the world. ALD is becoming more common in many parts of Asia but is decreasing in Western Europe".
The results clearly and strongly suggested that reducing the intake of alcohol and following a healthy diet pattern is the best way to decrease the risk of liver diseases, including ALD.
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detox agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
Scientists on finding a natural ingredient that processes liver protective effects evaluated the preventive effects of ethanolic extract from artichoke against acute alcohol-induced liver injury in mice.
Selected male mice were treated with an ethanolic extract of artichoke (0.4, 0.8, and 1.6 g/kg body weight) by gavage once daily before administrated up to 40% alcohol (12 mL/kg body weight) orally 1 h after artichoke treatment for 10 consecutive days.
Injection of artichoke extract not only significantly prevented elevated levels of aspartate aminotransferase, alanine aminotransferase, and the liver oxidative stress markers but also reduced the levels of triglyceride, and total cholesterol.
Artichoke treatment mice also restored the levels of antioxidant enzymes which were reduced by the injection of alcohol.
According to the immunohistochemical analysis, artichoke also suppressed the levels of toll-like receptor (TLR) 4 which plays a critical role in the production of several pro-inflammatory, antiviral, and anti-bacterial cytokines and protein, nuclear factor-kappa B (NF-κB) associated with liver cells apoptosis in liver tissues.
The results indicated a liver protective activity in artichoke was attributed to the inhibition of the pro-inflammatory proteins in acute alcohol-induced liver injury mice.
In order to reveal more information about the liver protective effect of artichokes, researchers examined the herbal medicine against liver fibrosis, the main pathology of schistosomiasis, and its complications are the major cause of death in infected cases.
Mice selected for the study infected with Schistosoma mansoni (S. mansoni) were divided into 5 groups. The first three groups were given artichoke leaf extract (ALE), ALE + praziquantel (PZQ), and PZQ respectively. The 4th was a positive control and the 5th was the negative control group. and were compared to PZQ.
Injection of ALE and ALE + praziquantel (PZQ) caused a significant reduction of granuloma diameter, improvement of liver functions, and liver fibrosis.
Furthermore, ALE induced statistically significant changes in hepatic stellate cells (HSCs) distribution.
Moreover, ALE also reduced granuloma size by increasing HSCs recruitment inside granuloma and limited liver fibrosis by their inhibition in the peri- and inter-granuloma liver tissue.
Unfortunately, although, the herbal extract exerted a strong liver protective activity, it failed to treat S. mansoni infection.
Taken altogether, artichoke may be considered a functional remedy for the prevention and treatment of liver disease, pending the confirmation of large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Liver protective effects
(1) Protective Effects of Ethanolic Extracts from Artichoke, an Edible Herbal Medicine, against Acute Alcohol-Induced Liver Injury in Mice by Tang X1, Wei R2, Deng A3, Lei T. (PubMed)
(2) Artichoke leaf extract protects the liver of Schistosoma mansoni infected mice through modulation of hepatic stellate cell recruitment by Sharaf El-Deen SA1, Barakat RM2, Mohamed ASED. (PubMed)
(3) [Artichoke--the untapped potential of herbal medicine in the treatment of atherosclerosis and liver diseases].[Article in Polish] by Horoszkiewicz M1, Kulza M, Malinowska K, Woźniak A, Seńczuk-Przybyłowska M, Wachowiak A, Florek E.(PubMed)
(4) Alcoholic Liver Disease in Asia, Europe, and North America by Suthat Liangpunsakul, Paul Haber, and Geoff McCaughan. (PMC)
#Herbal #Artichoke Promotes Bowel Health through Its Probiotic Property, Researchers Suggest
Kyle J. Norton
Bowel problems may be a condition associated with some underlying diseases or syndrome including bowel incontinence, IBS, Colitis, Crohn's, constipation, or other bowel conditions.
Bowel problems can be cured if the causes of the problem are found.
The most common syndrome that does not associate with the underlying disease is constipation, a condition that affects bowel movements.
According to the statistics in the US, constipation affects approximately 2% of the population and the condition is more common in women than men.
Patients with constipation may experience symptoms of abdominal pain, bloating, and the feeling of not completely passing the bowel movement.
Chronic constipation is one of the common causes of hemorrhoids, anal fissures or fecal impaction.
Conventionally, constipation in most cases is treated by the use of a laxative. However long-term use of laxatives may induce diarrhea, intestinal obstruction, and particularly unbalanced levels of salts and minerals in your body.
Therefore, if you currently use one of the over-counter laxatives for the treatment of constipation, please make you know all the side effects for preventive measures.
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
In finding a natural compound with bowel health promotion activity, researchers compared the effects of probiotic-enriched artichokes on the treatment of the symptom profile and short-chain fatty acid (SCFA) production in constipated subjects with ordinary artichokes.
20 chronically constipated participants including 3 males and 17 female have selected to a double-blind method and a computer-generated randomization list.
Each patient consumed 180 g per day of ordinary artichokes or artichokes enriched with Lactobacillus paracasei IMPC 2.1 for 15 days.
According to the returned questionnaires, 80% of patients preferred probiotic-enriched artichokes compared to ordinary ones.
The satisfactory relief of symptoms was significantly higher in the probiotic-enriched artichoke compared to ordinary ones.
According to the Bristol stool scale the measurement of fecal retention was lower in the probiotic-enriched artichokes compared to higher in the artichoke group seconded to the control.
GSRS (Gastrointestinal Symptom Rating Scale) of constipation was significantly lower in the probiotic group compared with the baseline.
Furthermore, the short-chain fatty acid (SCFA) production and propionic acid were significantly higher in the probiotic group compared with the baseline.
In order to reveal more information on artichokes in the promotion of bowel health, researchers investigated the chemical compounds inulin and oligofructose, a class of fructans found in the Jerusalem artichoke.
Injection of inulin and oligofructose was found to stimulate the immune system of the body, decrease the pathogenic bacteria in the intestine, and relieve constipation.
Furthermore, inulin and oligofructose also displayed significant effects in the promotion of bowel health by protecting the colon against colon cancer.
Taken together, artichoke, particularly Jerusalem artichoke alone or combined with probiotics may be considered functional remedies for the improvement of bowel health, pending the validation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Randomised clinical trial: efficacy of Lactobacillus paracasei-enriched artichokes in the treatment of patients with functional constipation--a double-blind, controlled, crossover study by Riezzo G1, Orlando A, D'Attoma B, Guerra V, Valerio F, Lavermicocca P, De Candia S, Russo F. (PubMed)
(2) Applications of inulin and oligofructose in health and nutrition by Kaur N1, Gupta AK. (PubMed)
Bowel problems may be a condition associated with some underlying diseases or syndrome including bowel incontinence, IBS, Colitis, Crohn's, constipation, or other bowel conditions.
Bowel problems can be cured if the causes of the problem are found.
The most common syndrome that does not associate with the underlying disease is constipation, a condition that affects bowel movements.
According to the statistics in the US, constipation affects approximately 2% of the population and the condition is more common in women than men.
Patients with constipation may experience symptoms of abdominal pain, bloating, and the feeling of not completely passing the bowel movement.
Chronic constipation is one of the common causes of hemorrhoids, anal fissures or fecal impaction.
Conventionally, constipation in most cases is treated by the use of a laxative. However long-term use of laxatives may induce diarrhea, intestinal obstruction, and particularly unbalanced levels of salts and minerals in your body.
Therefore, if you currently use one of the over-counter laxatives for the treatment of constipation, please make you know all the side effects for preventive measures.
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
In finding a natural compound with bowel health promotion activity, researchers compared the effects of probiotic-enriched artichokes on the treatment of the symptom profile and short-chain fatty acid (SCFA) production in constipated subjects with ordinary artichokes.
20 chronically constipated participants including 3 males and 17 female have selected to a double-blind method and a computer-generated randomization list.
Each patient consumed 180 g per day of ordinary artichokes or artichokes enriched with Lactobacillus paracasei IMPC 2.1 for 15 days.
According to the returned questionnaires, 80% of patients preferred probiotic-enriched artichokes compared to ordinary ones.
The satisfactory relief of symptoms was significantly higher in the probiotic-enriched artichoke compared to ordinary ones.
According to the Bristol stool scale the measurement of fecal retention was lower in the probiotic-enriched artichokes compared to higher in the artichoke group seconded to the control.
GSRS (Gastrointestinal Symptom Rating Scale) of constipation was significantly lower in the probiotic group compared with the baseline.
Furthermore, the short-chain fatty acid (SCFA) production and propionic acid were significantly higher in the probiotic group compared with the baseline.
In order to reveal more information on artichokes in the promotion of bowel health, researchers investigated the chemical compounds inulin and oligofructose, a class of fructans found in the Jerusalem artichoke.
Injection of inulin and oligofructose was found to stimulate the immune system of the body, decrease the pathogenic bacteria in the intestine, and relieve constipation.
Furthermore, inulin and oligofructose also displayed significant effects in the promotion of bowel health by protecting the colon against colon cancer.
Taken together, artichoke, particularly Jerusalem artichoke alone or combined with probiotics may be considered functional remedies for the improvement of bowel health, pending the validation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Randomised clinical trial: efficacy of Lactobacillus paracasei-enriched artichokes in the treatment of patients with functional constipation--a double-blind, controlled, crossover study by Riezzo G1, Orlando A, D'Attoma B, Guerra V, Valerio F, Lavermicocca P, De Candia S, Russo F. (PubMed)
(2) Applications of inulin and oligofructose in health and nutrition by Kaur N1, Gupta AK. (PubMed)
#Bromelain Shows A Clinically Relevant Improvement in the WOMAC Disability Subscale in Osteoarthritis (OA) Similar to Those of Diclofenac with No Side Effects
By Kyle J. Norton
Osteoarthritis (OA), a form of arthritis, is a condition associated with aging-induced wear and tear on a joint or joint.
The condition is very common in older adults, affecting over 25 million people in the US with no sign of stopping.
According to the University of Porto Medical School, the differences in prevalence and incidence estimates of osteoarthritis (OA), according to the case definition, are in the knee, hip, and hand joints(3).
The characteristics of osteoarthritis are aching pain(5), stiffness(6), or difficulty in moving the joint or joints(7). The pain usually gets worse in a change of weather, at night.
In advanced diseases, pain can occur even at rest(8).
Today management of osteoarthritis (OA) focuses on pain relief and improved physical function through pharmacological, nonpharmacological, and surgical treatments(4).
Some researchers suggested that OA is not simply a disease related to aging or mechanical stress of joints but rather a “metabolic disorder(70)(71)” interrelated to lipid, metabolic, and humoral mediators(70).
Indeed, OA has been linked not only to obesity(46)(47) but also to other cardiovascular risk factors(72)(73), namely, diabetes(74), dyslipidemia, hypertension, and insulin resistance(75).
More precisely, the majority of patients with OA also suffer from one or more of the below conditions
* Hypertension
According to the University Health Network Research Institute, the economic burden incurred by RA significantly exceeds that related to OA and HBP(76)(77).
* Cardiovascular disease
According to Erasmus University Medical Centre, there is an association of atherosclerosis with osteoarthritis of the knee and hand joints in women(72)(73)(78).
*Peripheral vascular disease
According to Himchan Hospital, patients with osteoarthritis are associated with a risk of asymptomatic peripheral vascular disease(80). The average vessel wall thickness of the popliteal artery was 1.09 mm in patients with generalized OA, and 0.96 mm in the matched normal reference population(79).
* Congestive heart failure
Hypertension, diabetes, and older age have been shown to increase the risk of Congestive heart failure modestly(81).
* Renal function impairment
According to the Southampton University Hospitals NHS Trust, pain pharmacotherapies such as osteoarthritis (OA) or mixed OA and rheumatoid arthritis may increase the risk of adverse events in patients with concurrent cardiovascular (CV) or renal disease(83).
6. Diabetes
Several epidemiological and experimental data support the hypothesis that diabetes could be an independent risk factor for osteoarthritis (OA)(76)(85).
* Respiratory disease
People with respiratory disease are also at a higher risk to develop osteoarthritis (OA), including chronic cough and bilateral infiltrates on chest roentgenogram(86).
* High serum of cholesterol
There is an association between high serum cholesterol levels and both knee and generalized OA, according to the study of 113 females and 133 males with average ages 46 14.2 and 51.54 16.0 years by King Khalid University Hospital(87).
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
In finding a natural compound from healthy food for the treatment of inflammatory diseases, researchers examined the effects of bromelain on patients with osteoarthritis of the knee.
The randomized, double-blind placebo-controlled trial included 47 patients with a confirmed diagnosis of moderate to severe knee OA randomized to 12 weeks of bromelain 800 mg/day or placebo, with a 4-week follow-up.
According to the results from 31 patients who completed the trial, including 14 in the bromelain group and 17 in the placebo group, both treatment groups showed clinically relevant improvement in the WOMAC disability subscale only with a mild adverse outcome.
In order to reveal and confirm the effects of bromelain on OA, a joint randomized, single-blind, active-controlled pilot study. led by Mahidol University was conducted in patients with OA for 16 weeks.
40 knee OA patients enrolled in the study were randomized to receive oral bromelain (500 mg/day) or diclofenac (100 mg/day).
According to the tested assays,
* At week 4, the improvement of total WOMAC and pain subscales from baseline was observed in both groups, however, two patients in the diclofenac treatment group showed adverse effects that lead to discontinuation of diclofenac.
* At week 16, the bromelain treatment group showed a significant improvement in all aspects, including total WOMAC scores (12.2 versus 25.5), pain subscales (2.4 versus 5.6), stiffness subscales (0.8 versus 2.0), and function subscales (9.1 versus 17.9), and physical component of SF-36 (73.3 versus 65.4), compared to baseline values.
* Also compared to the based line, the bromelain-treated group also showed a decrease of plasma MDA and LPS-stimulated PGE2 production,
* Bromelain exerted a similar effect to those of diclofenac after 4 weeks.
Taken altogether, bromelain used alone may be considered supplements for the prevention and treatment of osteoarthritis, pending the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Bromelain as an adjunctive treatment for moderate-to-severe osteoarthritis of the knee: a randomized placebo-controlled pilot study by Brien S1, Lewith G, Walker AF, Middleton R, Prescott P, Bundy R. (PubMed)
(2) Improved WOMAC score following 16-week treatment with bromelain for knee osteoarthritis by Kasemsuk T1, Saengpetch N2, Sibmooh N1, Unchern S. (PubMed)
(3) Most Common Disease of Elder: The Clinical Trials and Studies of musculoskeletal disorders(MSDs) - Osteoarthritis: Diseases associated with Osteoarthritis by Kyle J. Norton
Osteoarthritis (OA), a form of arthritis, is a condition associated with aging-induced wear and tear on a joint or joint.
The condition is very common in older adults, affecting over 25 million people in the US with no sign of stopping.
According to the University of Porto Medical School, the differences in prevalence and incidence estimates of osteoarthritis (OA), according to the case definition, are in the knee, hip, and hand joints(3).
The characteristics of osteoarthritis are aching pain(5), stiffness(6), or difficulty in moving the joint or joints(7). The pain usually gets worse in a change of weather, at night.
In advanced diseases, pain can occur even at rest(8).
Today management of osteoarthritis (OA) focuses on pain relief and improved physical function through pharmacological, nonpharmacological, and surgical treatments(4).
Some researchers suggested that OA is not simply a disease related to aging or mechanical stress of joints but rather a “metabolic disorder(70)(71)” interrelated to lipid, metabolic, and humoral mediators(70).
Indeed, OA has been linked not only to obesity(46)(47) but also to other cardiovascular risk factors(72)(73), namely, diabetes(74), dyslipidemia, hypertension, and insulin resistance(75).
More precisely, the majority of patients with OA also suffer from one or more of the below conditions
* Hypertension
According to the University Health Network Research Institute, the economic burden incurred by RA significantly exceeds that related to OA and HBP(76)(77).
* Cardiovascular disease
According to Erasmus University Medical Centre, there is an association of atherosclerosis with osteoarthritis of the knee and hand joints in women(72)(73)(78).
*Peripheral vascular disease
According to Himchan Hospital, patients with osteoarthritis are associated with a risk of asymptomatic peripheral vascular disease(80). The average vessel wall thickness of the popliteal artery was 1.09 mm in patients with generalized OA, and 0.96 mm in the matched normal reference population(79).
* Congestive heart failure
Hypertension, diabetes, and older age have been shown to increase the risk of Congestive heart failure modestly(81).
* Renal function impairment
According to the Southampton University Hospitals NHS Trust, pain pharmacotherapies such as osteoarthritis (OA) or mixed OA and rheumatoid arthritis may increase the risk of adverse events in patients with concurrent cardiovascular (CV) or renal disease(83).
6. Diabetes
Several epidemiological and experimental data support the hypothesis that diabetes could be an independent risk factor for osteoarthritis (OA)(76)(85).
* Respiratory disease
People with respiratory disease are also at a higher risk to develop osteoarthritis (OA), including chronic cough and bilateral infiltrates on chest roentgenogram(86).
* High serum of cholesterol
There is an association between high serum cholesterol levels and both knee and generalized OA, according to the study of 113 females and 133 males with average ages 46 14.2 and 51.54 16.0 years by King Khalid University Hospital(87).
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
In finding a natural compound from healthy food for the treatment of inflammatory diseases, researchers examined the effects of bromelain on patients with osteoarthritis of the knee.
The randomized, double-blind placebo-controlled trial included 47 patients with a confirmed diagnosis of moderate to severe knee OA randomized to 12 weeks of bromelain 800 mg/day or placebo, with a 4-week follow-up.
According to the results from 31 patients who completed the trial, including 14 in the bromelain group and 17 in the placebo group, both treatment groups showed clinically relevant improvement in the WOMAC disability subscale only with a mild adverse outcome.
In order to reveal and confirm the effects of bromelain on OA, a joint randomized, single-blind, active-controlled pilot study. led by Mahidol University was conducted in patients with OA for 16 weeks.
40 knee OA patients enrolled in the study were randomized to receive oral bromelain (500 mg/day) or diclofenac (100 mg/day).
According to the tested assays,
* At week 4, the improvement of total WOMAC and pain subscales from baseline was observed in both groups, however, two patients in the diclofenac treatment group showed adverse effects that lead to discontinuation of diclofenac.
* At week 16, the bromelain treatment group showed a significant improvement in all aspects, including total WOMAC scores (12.2 versus 25.5), pain subscales (2.4 versus 5.6), stiffness subscales (0.8 versus 2.0), and function subscales (9.1 versus 17.9), and physical component of SF-36 (73.3 versus 65.4), compared to baseline values.
* Also compared to the based line, the bromelain-treated group also showed a decrease of plasma MDA and LPS-stimulated PGE2 production,
* Bromelain exerted a similar effect to those of diclofenac after 4 weeks.
Taken altogether, bromelain used alone may be considered supplements for the prevention and treatment of osteoarthritis, pending the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Bromelain as an adjunctive treatment for moderate-to-severe osteoarthritis of the knee: a randomized placebo-controlled pilot study by Brien S1, Lewith G, Walker AF, Middleton R, Prescott P, Bundy R. (PubMed)
(2) Improved WOMAC score following 16-week treatment with bromelain for knee osteoarthritis by Kasemsuk T1, Saengpetch N2, Sibmooh N1, Unchern S. (PubMed)
(3) Most Common Disease of Elder: The Clinical Trials and Studies of musculoskeletal disorders(MSDs) - Osteoarthritis: Diseases associated with Osteoarthritis by Kyle J. Norton
Short-Chain Fructooligosaccharides (FOS) Found in #Herbal #Artichoke Health Benefits in the Inhibition of #Diabetes and #CardiovascularDisease
Kyle J. Norton
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
Fructooligosaccharides (FOS), are oligosaccharides, a molecule made up of a small group of these sugar,
Due to its nature as a natural source of sugar and low in calories, FOS may be used as an alternative sweetener as intake of FOS does not cause a spike in blood sugar.
FOS are considered prebiotics. Intake of FOS can increase the levels of good bacteria in the intestine, leading to a healthy ratio of gut microbiota.
Digestively, FOS contains high levels of soluble fiber which has been found to improve bowel function. Consumption of FOS also increased fecal bolus and the frequency of depositions, while a dose of 4-15 g/day given to healthy subjects has been found to reduce constipation.
According to the study, FOS also showed anti-toxicity, carcinogenicity, and genotoxic effects.
FOS improved mineral absorption by decreasing levels of pH in the colon, thus facilitating the absorption of mineral ions from the intestine, mainly calcium and magnesium
Furthermore, FOS has also been found in studies to decrease levels of serum cholesterol, and triacylglycerols, the lead causes of cardiovascular diseases.
By modulating the levels of phospholipids, FOS lowers the risk of coronary heart disease, inflammation, or cancer, particularly colon cancer.
In foods, FOS are increasingly included in food products and infant formulas for their prebiotic effect in stimulating the growth of nonpathogenic intestinal microflora.
In the examined the effects of chronic ingestion of short-chain fructooligosaccharides (FOS), an indigestible carbohydrate, on hepatic glucose production, insulin-mediated glucose metabolism, erythrocyte insulin binding, and blood lipids in 12 healthy volunteers selected received either 20 g FOS/d or sucrose for 4 wk in a double-blind crossover design, researchers found that the mean (+/- SEM) basal hepatic glucose production was lower after FOS than after sucrose consumption, through the effects on insulin-stimulated glucose metabolism in healthy subjects.
Taken together, artichoke processes many health benefits that may be used as a functional remedy for disease prevention in healthy subjects, pending to the validation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Dietary fructooligosaccharides and potential benefits on health by Sabater-Molina M1, Larqué E, Torrella F, Zamora S. (PubMed)
(2) Chronic consumption of short-chain fructooligosaccharides by healthy subjects decreased basal hepatic glucose production but had no effect on insulin-stimulated glucose metabolism by Luo J1, Rizkalla SW, Alamowitch C, Boussairi A, Blayo A, Barry JL, Laffitte A, Guyon F, Bornet FR, Slama G. (PubMed)
(3) Fructooligosaccharides: a review by Fishbein L1, Kaplan M, Gough M. (PubMed)
(4) Fructooligosaccharides: Applications and Health benefits- a review by SHUBHANGI S. KHANVILKAR, Shalini S. Arya*
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
Fructooligosaccharides (FOS), are oligosaccharides, a molecule made up of a small group of these sugar,
Due to its nature as a natural source of sugar and low in calories, FOS may be used as an alternative sweetener as intake of FOS does not cause a spike in blood sugar.
FOS are considered prebiotics. Intake of FOS can increase the levels of good bacteria in the intestine, leading to a healthy ratio of gut microbiota.
Digestively, FOS contains high levels of soluble fiber which has been found to improve bowel function. Consumption of FOS also increased fecal bolus and the frequency of depositions, while a dose of 4-15 g/day given to healthy subjects has been found to reduce constipation.
According to the study, FOS also showed anti-toxicity, carcinogenicity, and genotoxic effects.
FOS improved mineral absorption by decreasing levels of pH in the colon, thus facilitating the absorption of mineral ions from the intestine, mainly calcium and magnesium
Furthermore, FOS has also been found in studies to decrease levels of serum cholesterol, and triacylglycerols, the lead causes of cardiovascular diseases.
By modulating the levels of phospholipids, FOS lowers the risk of coronary heart disease, inflammation, or cancer, particularly colon cancer.
In foods, FOS are increasingly included in food products and infant formulas for their prebiotic effect in stimulating the growth of nonpathogenic intestinal microflora.
In the examined the effects of chronic ingestion of short-chain fructooligosaccharides (FOS), an indigestible carbohydrate, on hepatic glucose production, insulin-mediated glucose metabolism, erythrocyte insulin binding, and blood lipids in 12 healthy volunteers selected received either 20 g FOS/d or sucrose for 4 wk in a double-blind crossover design, researchers found that the mean (+/- SEM) basal hepatic glucose production was lower after FOS than after sucrose consumption, through the effects on insulin-stimulated glucose metabolism in healthy subjects.
Taken together, artichoke processes many health benefits that may be used as a functional remedy for disease prevention in healthy subjects, pending to the validation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Dietary fructooligosaccharides and potential benefits on health by Sabater-Molina M1, Larqué E, Torrella F, Zamora S. (PubMed)
(2) Chronic consumption of short-chain fructooligosaccharides by healthy subjects decreased basal hepatic glucose production but had no effect on insulin-stimulated glucose metabolism by Luo J1, Rizkalla SW, Alamowitch C, Boussairi A, Blayo A, Barry JL, Laffitte A, Guyon F, Bornet FR, Slama G. (PubMed)
(3) Fructooligosaccharides: a review by Fishbein L1, Kaplan M, Gough M. (PubMed)
(4) Fructooligosaccharides: Applications and Health benefits- a review by SHUBHANGI S. KHANVILKAR, Shalini S. Arya*
#Anthocyanin-rich #Bilberry Inhibits the Active-#UlcerativeColitis, through Its Antioxidative and Anti-Inflammatory Activity
Kyle J. Norton
Ulcerative colitis (UC) is a type of inflammatory bowel disease (IBD) caused by the inflammation associated with the colon and rectum.
Symptoms of UC is totally depending on the severity of the disease, including diarrhea, often with blood or pus, persistent abdominal pain, rectal pain, and bleeding, particularly the inability to defecate despite the urgency.
Some patients with UC may also have symptoms of weight loss, and fatigue fever.
According to the statistics in the US, out of 1.6 million Americans with inflammatory bowel disease, 907,000 of them have ulcerative colitis.
Depending on the location, the most common types of UC can be classified into
* Acute severe ulcerative colitis is a medical emergency that requires immediate hospitalization. The condition affects the entire colon with severe acute symptoms of pain, profuse diarrhea, bleeding, and fever.
* Ulcerative proctitis is an Inflammation of the anus (rectum), inducing symptoms of rectal bleeding.
* Proctosigmoiditis is an Inflammation involved in the rectum and sigmoid colon (lower end of the colon).
The exact causes of UC are not cleared. Some researchers suggested there are a complex interaction of genetics, immune response, and environmental triggers that cause the onset of the disease.
The most common risk factors of UC include genetic preposition, autoimmune diseases, smoking, use of certain medications such as antibiotics, and smoking.
Some researchers suggested that UC may be correlated with the increase of age as the disease affected 10–30% of the population older than 60 years.
Dr. Wei-Chen, the lead scientist wrote, " Elderly patients with UC will be seen more frequently with the aging of the population and increasing incidence of UC. The management of UC in the elderly population is more complex due to comorbidities and polypharmacy".
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant has been used as herb in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, psoriasis, diabetes, etc.
In finding a natural compound or whole food for the treatment of ulcerative colitis (UC), as a significant fraction of patients with ulcerative colitis (UC) is not sufficiently controlled with conventional therapy or suffer from therapy-related side effects, researchers examined the anthocyanin-rich bilberry extract (ARBE) on the colon specimens obtained during an open pilot study using ARBE for the treatment of mild-to-moderate UC.
Pretreatment of ARBE inhibited the expression of IFN-γ-receptor 2 which plays a critical role in the regulation of mediated immune responses and organ-specific autoimmunity in human THP-1 monocytic cells.
After 6 weeks of treatment, ARBE treatment revealed reduced production of the pro-inflammatory cytokines including IFN-γ and TNF-α.
Furthermore, ARBE treatment featured enhanced levels of Th17-cell-specific cytokine IL-22 and immunoregulatory cytokine IL-10 by restoring the balance between Th17 and Treg cells and preventing the risk of chronic inflammation and pathogenesis of many autoimmune diseases.
Dr. Roth S, the lead scientist after taking other factors into account wrote, "a molecular mechanism underlying the anti-inflammatory effects of ARBE treatment in UC patients by modulating T-cell cytokine signaling and inhibiting IFN-γ signal transduction".
In order to reveal more information about the bilberry (Vaccinium myrtillus) property on UC, researchers analyzed the antioxidative and anti-inflammatory effects with an aim to explore the therapeutic potential of bilberries in the active UC.
The open pilot trial with a total follow-up of 9 weeks the effect of a daily standardized anthocyanin-rich bilberry preparation included 13 patients with mild to moderate UC.
At the end of the 6-week treatment interval, 63.4% of patients achieved remission, the primary endpoint, while 90.9% of patients showed a response.
In all patients, a decrease in total Mayo score was detected (mean: 6.5 and 3.6 at screening and week 7, respectively; p<0.001).
Fecal calprotectin levels significantly decreased during the treatment phase (baseline: mean 778 μg/g, range 192-1790 μg/g; end of treatment: mean 305 μg/g, range <30-1586 μg/g; p=0.049), including 4 patients achieving undetectable levels at end of treatment.
No serious adverse events were observed.
The finding strongly supports the regular use of standardized anthocyanin-rich bilberry preparation in UC in humans.
Dr. Biedermann L, said at the end of the experience, "These results clearly indicate a therapeutic potential of bilberries in UC. Further studies on mechanisms and randomized clinical trials are warranted".
Taken together, bilberry-processed abundantly bioactive compound anthocyanin may be considered a functional remedy for the prevention and treatment of UC, pending to the validation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Bilberry-Derived Anthocyanins Modulate Cytokine Expression in the Intestine of Patients with Ulcerative Colitis by Roth S1, Spalinger MR1, Gottier C1, Biedermann L1, Zeitz J1, Lang S1, Weber A2, Rogler G1,3, Scharl M. (PubMed)
(2) Bilberry ingestion improves disease activity in mild to moderate ulcerative colitis - an open pilot study by Biedermann L1, Mwinyi J, Scharl M, Frei P, Zeitz J, Kullak-Ublick GA, Vavricka SR, Fried M, Weber A, Humpf HU, Peschke S, Jetter A, Krammer G, Rogler G. (PubMed)
(3) Ulcerative Colitis in Elderly People: An Emerging Issue by Wei-ChenLin, Ming-JenChen, Cheng-HsinChua, Tsang-EnWang, Horng-YuanWang, Chen-WangChang. (Science Direct)
Ulcerative colitis (UC) is a type of inflammatory bowel disease (IBD) caused by the inflammation associated with the colon and rectum.
Symptoms of UC is totally depending on the severity of the disease, including diarrhea, often with blood or pus, persistent abdominal pain, rectal pain, and bleeding, particularly the inability to defecate despite the urgency.
Some patients with UC may also have symptoms of weight loss, and fatigue fever.
According to the statistics in the US, out of 1.6 million Americans with inflammatory bowel disease, 907,000 of them have ulcerative colitis.
Depending on the location, the most common types of UC can be classified into
* Acute severe ulcerative colitis is a medical emergency that requires immediate hospitalization. The condition affects the entire colon with severe acute symptoms of pain, profuse diarrhea, bleeding, and fever.
* Ulcerative proctitis is an Inflammation of the anus (rectum), inducing symptoms of rectal bleeding.
* Proctosigmoiditis is an Inflammation involved in the rectum and sigmoid colon (lower end of the colon).
The exact causes of UC are not cleared. Some researchers suggested there are a complex interaction of genetics, immune response, and environmental triggers that cause the onset of the disease.
The most common risk factors of UC include genetic preposition, autoimmune diseases, smoking, use of certain medications such as antibiotics, and smoking.
Some researchers suggested that UC may be correlated with the increase of age as the disease affected 10–30% of the population older than 60 years.
Dr. Wei-Chen, the lead scientist wrote, " Elderly patients with UC will be seen more frequently with the aging of the population and increasing incidence of UC. The management of UC in the elderly population is more complex due to comorbidities and polypharmacy".
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant has been used as herb in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, psoriasis, diabetes, etc.
In finding a natural compound or whole food for the treatment of ulcerative colitis (UC), as a significant fraction of patients with ulcerative colitis (UC) is not sufficiently controlled with conventional therapy or suffer from therapy-related side effects, researchers examined the anthocyanin-rich bilberry extract (ARBE) on the colon specimens obtained during an open pilot study using ARBE for the treatment of mild-to-moderate UC.
Pretreatment of ARBE inhibited the expression of IFN-γ-receptor 2 which plays a critical role in the regulation of mediated immune responses and organ-specific autoimmunity in human THP-1 monocytic cells.
After 6 weeks of treatment, ARBE treatment revealed reduced production of the pro-inflammatory cytokines including IFN-γ and TNF-α.
Furthermore, ARBE treatment featured enhanced levels of Th17-cell-specific cytokine IL-22 and immunoregulatory cytokine IL-10 by restoring the balance between Th17 and Treg cells and preventing the risk of chronic inflammation and pathogenesis of many autoimmune diseases.
Dr. Roth S, the lead scientist after taking other factors into account wrote, "a molecular mechanism underlying the anti-inflammatory effects of ARBE treatment in UC patients by modulating T-cell cytokine signaling and inhibiting IFN-γ signal transduction".
In order to reveal more information about the bilberry (Vaccinium myrtillus) property on UC, researchers analyzed the antioxidative and anti-inflammatory effects with an aim to explore the therapeutic potential of bilberries in the active UC.
The open pilot trial with a total follow-up of 9 weeks the effect of a daily standardized anthocyanin-rich bilberry preparation included 13 patients with mild to moderate UC.
At the end of the 6-week treatment interval, 63.4% of patients achieved remission, the primary endpoint, while 90.9% of patients showed a response.
In all patients, a decrease in total Mayo score was detected (mean: 6.5 and 3.6 at screening and week 7, respectively; p<0.001).
Fecal calprotectin levels significantly decreased during the treatment phase (baseline: mean 778 μg/g, range 192-1790 μg/g; end of treatment: mean 305 μg/g, range <30-1586 μg/g; p=0.049), including 4 patients achieving undetectable levels at end of treatment.
No serious adverse events were observed.
The finding strongly supports the regular use of standardized anthocyanin-rich bilberry preparation in UC in humans.
Dr. Biedermann L, said at the end of the experience, "These results clearly indicate a therapeutic potential of bilberries in UC. Further studies on mechanisms and randomized clinical trials are warranted".
Taken together, bilberry-processed abundantly bioactive compound anthocyanin may be considered a functional remedy for the prevention and treatment of UC, pending to the validation of larger sample size and multicenter human study.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Bilberry-Derived Anthocyanins Modulate Cytokine Expression in the Intestine of Patients with Ulcerative Colitis by Roth S1, Spalinger MR1, Gottier C1, Biedermann L1, Zeitz J1, Lang S1, Weber A2, Rogler G1,3, Scharl M. (PubMed)
(2) Bilberry ingestion improves disease activity in mild to moderate ulcerative colitis - an open pilot study by Biedermann L1, Mwinyi J, Scharl M, Frei P, Zeitz J, Kullak-Ublick GA, Vavricka SR, Fried M, Weber A, Humpf HU, Peschke S, Jetter A, Krammer G, Rogler G. (PubMed)
(3) Ulcerative Colitis in Elderly People: An Emerging Issue by Wei-ChenLin, Ming-JenChen, Cheng-HsinChua, Tsang-EnWang, Horng-YuanWang, Chen-WangChang. (Science Direct)
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